Marek s disease virus serotype 2 MDV2

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus; Gallid alphaherpesvirus 3

Average proteome isoelectric point is 6.86

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 65 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1P7U0A2|A0A1P7U0A2_9ALPH Capsid vertex component 1 OS=Marek's disease virus serotype 2 MDV2 OX=36353 GN=ORF 22 PE=3 SV=1
MM1 pKa = 6.81PWYY4 pKa = 10.2RR5 pKa = 11.84RR6 pKa = 11.84GYY8 pKa = 8.48HH9 pKa = 4.6TTKK12 pKa = 9.62PTDD15 pKa = 3.42CDD17 pKa = 3.21ILLDD21 pKa = 4.21YY22 pKa = 11.04IGDD25 pKa = 3.93EE26 pKa = 3.99QLEE29 pKa = 4.55TNMQDD34 pKa = 2.99TEE36 pKa = 4.99SIVTRR41 pKa = 11.84VSDD44 pKa = 6.25DD45 pKa = 3.42IDD47 pKa = 5.28CEE49 pKa = 4.14DD50 pKa = 3.59AAEE53 pKa = 4.04YY54 pKa = 8.89ATMSSYY60 pKa = 11.33LSGSIFTISKK70 pKa = 9.63SCDD73 pKa = 3.23MNPKK77 pKa = 7.36FTRR80 pKa = 11.84YY81 pKa = 8.98VVLSWLSAFVLRR93 pKa = 11.84PSCCIIFLVYY103 pKa = 11.09AMDD106 pKa = 3.56GHH108 pKa = 6.9DD109 pKa = 3.95NRR111 pKa = 11.84FLILGATITAVFYY124 pKa = 8.44GTLLLEE130 pKa = 4.33TYY132 pKa = 10.92YY133 pKa = 10.11MYY135 pKa = 11.14RR136 pKa = 11.84NIKK139 pKa = 9.27NDD141 pKa = 3.56VMPMDD146 pKa = 4.13NCQQIFVGILSTLGAVIFGVFSYY169 pKa = 11.09RR170 pKa = 11.84MVFQDD175 pKa = 3.42PRR177 pKa = 11.84FMEE180 pKa = 4.29KK181 pKa = 10.24VLQLEE186 pKa = 4.69EE187 pKa = 3.97NDD189 pKa = 3.75KK190 pKa = 10.87TDD192 pKa = 3.17GAVVYY197 pKa = 10.05LLMGATITYY206 pKa = 7.92ATVAVSDD213 pKa = 3.92ALGFLLPRR221 pKa = 11.84LWTRR225 pKa = 11.84ALIKK229 pKa = 10.01TCVPFF234 pKa = 5.21

Molecular weight: 26.64 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|O89248|O89248_9ALPH Membrane protein OS=Marek's disease virus serotype 2 MDV2 OX=36353 GN=UL49.5 PE=3 SV=1
MM1 pKa = 7.7GDD3 pKa = 3.1SDD5 pKa = 3.61RR6 pKa = 11.84RR7 pKa = 11.84KK8 pKa = 9.0SSRR11 pKa = 11.84RR12 pKa = 11.84RR13 pKa = 11.84STMRR17 pKa = 11.84TSPDD21 pKa = 2.86NSAHH25 pKa = 6.24ISSTRR30 pKa = 11.84ARR32 pKa = 11.84RR33 pKa = 11.84DD34 pKa = 3.04SSKK37 pKa = 11.15NEE39 pKa = 3.82SPDD42 pKa = 3.78RR43 pKa = 11.84ISPPSHH49 pKa = 5.78SLQRR53 pKa = 11.84RR54 pKa = 11.84RR55 pKa = 11.84SVKK58 pKa = 9.89IEE60 pKa = 4.0RR61 pKa = 11.84KK62 pKa = 9.71DD63 pKa = 3.53SSSEE67 pKa = 4.02TQRR70 pKa = 11.84GEE72 pKa = 4.1SLSSKK77 pKa = 9.87VRR79 pKa = 11.84AKK81 pKa = 10.36PGARR85 pKa = 11.84AIEE88 pKa = 4.05KK89 pKa = 10.6GKK91 pKa = 10.1FAFSTTPASATSTWRR106 pKa = 11.84SNTLVYY112 pKa = 10.61NEE114 pKa = 5.31RR115 pKa = 11.84IFCGAVAAVAQYY127 pKa = 10.11HH128 pKa = 7.1AYY130 pKa = 10.29RR131 pKa = 11.84GALSLWRR138 pKa = 11.84RR139 pKa = 11.84NAPRR143 pKa = 11.84TNAEE147 pKa = 3.97LEE149 pKa = 4.22EE150 pKa = 4.1FLARR154 pKa = 11.84AIIKK158 pKa = 8.5ITIQEE163 pKa = 4.25GANLLDD169 pKa = 3.83EE170 pKa = 5.86AEE172 pKa = 4.13ACTRR176 pKa = 11.84KK177 pKa = 10.16LSEE180 pKa = 4.29EE181 pKa = 4.33SGLSPDD187 pKa = 3.2MGNPKK192 pKa = 9.99SRR194 pKa = 11.84SQYY197 pKa = 9.87GKK199 pKa = 10.05RR200 pKa = 11.84DD201 pKa = 3.55GDD203 pKa = 3.35EE204 pKa = 3.97STPVDD209 pKa = 3.36KK210 pKa = 10.49RR211 pKa = 11.84DD212 pKa = 3.64RR213 pKa = 11.84RR214 pKa = 11.84SKK216 pKa = 9.51TPGRR220 pKa = 11.84APTTSRR226 pKa = 11.84RR227 pKa = 11.84HH228 pKa = 4.88YY229 pKa = 10.07SSSRR233 pKa = 11.84GNYY236 pKa = 9.31SSEE239 pKa = 4.21SEE241 pKa = 4.1

Molecular weight: 26.88 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

65

0

65

34710

81

3064

534.0

59.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.199 ± 0.28

2.371 ± 0.163

5.725 ± 0.198

5.246 ± 0.139

3.881 ± 0.178

5.938 ± 0.143

2.285 ± 0.095

5.454 ± 0.155

3.786 ± 0.158

9.476 ± 0.147

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.452 ± 0.1

3.584 ± 0.111

5.056 ± 0.204

2.633 ± 0.11

7.312 ± 0.264

8.459 ± 0.258

6.384 ± 0.156

6.502 ± 0.152

1.066 ± 0.067

3.192 ± 0.12
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski