Amino acid dipepetide frequency for Apis mellifera associated microvirus 34

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.079AlaAla: 6.079 ± 2.348
0.76AlaCys: 0.76 ± 0.522
6.079AlaAsp: 6.079 ± 2.614
8.359AlaGlu: 8.359 ± 4.241
4.559AlaPhe: 4.559 ± 1.621
4.559AlaGly: 4.559 ± 2.619
2.28AlaHis: 2.28 ± 1.565
3.04AlaIle: 3.04 ± 1.126
3.799AlaLys: 3.799 ± 2.969
4.559AlaLeu: 4.559 ± 2.608
3.04AlaMet: 3.04 ± 1.227
3.799AlaAsn: 3.799 ± 1.969
2.28AlaPro: 2.28 ± 1.565
4.559AlaGln: 4.559 ± 3.072
3.04AlaArg: 3.04 ± 1.513
2.28AlaSer: 2.28 ± 0.568
3.799AlaThr: 3.799 ± 1.435
6.839AlaVal: 6.839 ± 1.297
0.76AlaTrp: 0.76 ± 0.522
2.28AlaTyr: 2.28 ± 1.565
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.76CysGlu: 0.76 ± 0.522
0.76CysPhe: 0.76 ± 0.743
0.76CysGly: 0.76 ± 0.743
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.28CysLeu: 2.28 ± 1.261
0.76CysMet: 0.76 ± 0.522
0.76CysAsn: 0.76 ± 0.743
0.76CysPro: 0.76 ± 0.743
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.76CysTrp: 0.76 ± 0.743
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.559AspAla: 4.559 ± 3.745
1.52AspCys: 1.52 ± 1.486
1.52AspAsp: 1.52 ± 1.486
1.52AspGlu: 1.52 ± 1.043
3.04AspPhe: 3.04 ± 1.785
4.559AspGly: 4.559 ± 1.469
0.76AspHis: 0.76 ± 0.522
3.04AspIle: 3.04 ± 1.602
3.04AspLys: 3.04 ± 1.126
3.04AspLeu: 3.04 ± 1.387
0.76AspMet: 0.76 ± 0.522
2.28AspAsn: 2.28 ± 0.996
1.52AspPro: 1.52 ± 1.265
4.559AspGln: 4.559 ± 3.189
4.559AspArg: 4.559 ± 1.733
3.04AspSer: 3.04 ± 0.876
2.28AspThr: 2.28 ± 0.997
4.559AspVal: 4.559 ± 2.455
3.04AspTrp: 3.04 ± 1.291
3.799AspTyr: 3.799 ± 1.001
0.0AspXaa: 0.0 ± 0.0
Glu
6.839GluAla: 6.839 ± 4.398
0.76GluCys: 0.76 ± 0.743
3.799GluAsp: 3.799 ± 1.41
4.559GluGlu: 4.559 ± 1.19
3.799GluPhe: 3.799 ± 1.13
2.28GluGly: 2.28 ± 0.996
0.0GluHis: 0.0 ± 0.0
3.04GluIle: 3.04 ± 1.269
10.638GluLys: 10.638 ± 4.607
6.839GluLeu: 6.839 ± 1.471
2.28GluMet: 2.28 ± 1.44
0.0GluAsn: 0.0 ± 0.0
2.28GluPro: 2.28 ± 0.867
3.04GluGln: 3.04 ± 0.788
3.04GluArg: 3.04 ± 1.628
4.559GluSer: 4.559 ± 3.072
3.04GluThr: 3.04 ± 1.45
3.799GluVal: 3.799 ± 2.006
3.04GluTrp: 3.04 ± 1.387
2.28GluTyr: 2.28 ± 1.261
0.0GluXaa: 0.0 ± 0.0
Phe
2.28PheAla: 2.28 ± 1.565
0.0PheCys: 0.0 ± 0.0
1.52PheAsp: 1.52 ± 1.043
2.28PheGlu: 2.28 ± 1.544
2.28PhePhe: 2.28 ± 1.261
2.28PheGly: 2.28 ± 1.261
0.0PheHis: 0.0 ± 0.0
1.52PheIle: 1.52 ± 1.043
1.52PheLys: 1.52 ± 1.265
4.559PheLeu: 4.559 ± 2.072
3.04PheMet: 3.04 ± 0.669
6.079PheAsn: 6.079 ± 1.861
2.28PhePro: 2.28 ± 0.867
1.52PheGln: 1.52 ± 1.432
0.76PheArg: 0.76 ± 0.522
3.04PheSer: 3.04 ± 0.625
2.28PheThr: 2.28 ± 0.996
6.079PheVal: 6.079 ± 0.92
0.76PheTrp: 0.76 ± 0.522
1.52PheTyr: 1.52 ± 0.893
0.0PheXaa: 0.0 ± 0.0
Gly
1.52GlyAla: 1.52 ± 1.043
0.0GlyCys: 0.0 ± 0.0
3.799GlyAsp: 3.799 ± 2.609
3.799GlyGlu: 3.799 ± 0.944
1.52GlyPhe: 1.52 ± 1.043
5.319GlyGly: 5.319 ± 2.386
0.0GlyHis: 0.0 ± 0.0
1.52GlyIle: 1.52 ± 1.077
3.04GlyLys: 3.04 ± 1.231
4.559GlyLeu: 4.559 ± 1.947
1.52GlyMet: 1.52 ± 0.961
2.28GlyAsn: 2.28 ± 1.31
1.52GlyPro: 1.52 ± 0.693
0.0GlyGln: 0.0 ± 0.0
3.799GlyArg: 3.799 ± 1.769
6.839GlySer: 6.839 ± 1.22
6.079GlyThr: 6.079 ± 1.991
3.799GlyVal: 3.799 ± 1.027
1.52GlyTrp: 1.52 ± 0.894
4.559GlyTyr: 4.559 ± 1.136
0.0GlyXaa: 0.0 ± 0.0
His
0.76HisAla: 0.76 ± 0.743
0.0HisCys: 0.0 ± 0.0
2.28HisAsp: 2.28 ± 1.261
0.76HisGlu: 0.76 ± 0.522
3.799HisPhe: 3.799 ± 1.186
1.52HisGly: 1.52 ± 1.043
0.76HisHis: 0.76 ± 0.522
0.76HisIle: 0.76 ± 0.716
0.0HisLys: 0.0 ± 0.0
3.04HisLeu: 3.04 ± 1.291
0.0HisMet: 0.0 ± 0.0
1.52HisAsn: 1.52 ± 1.043
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.52HisArg: 1.52 ± 0.616
0.76HisSer: 0.76 ± 0.716
0.0HisThr: 0.0 ± 0.0
0.76HisVal: 0.76 ± 0.522
0.0HisTrp: 0.0 ± 0.0
0.76HisTyr: 0.76 ± 0.743
0.0HisXaa: 0.0 ± 0.0
Ile
3.799IleAla: 3.799 ± 0.881
0.0IleCys: 0.0 ± 0.0
2.28IleAsp: 2.28 ± 0.832
1.52IleGlu: 1.52 ± 1.043
2.28IlePhe: 2.28 ± 1.31
0.76IleGly: 0.76 ± 0.743
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
3.04IleLys: 3.04 ± 1.895
4.559IleLeu: 4.559 ± 1.304
2.28IleMet: 2.28 ± 0.933
0.76IleAsn: 0.76 ± 0.522
0.76IlePro: 0.76 ± 0.522
1.52IleGln: 1.52 ± 0.894
2.28IleArg: 2.28 ± 0.997
1.52IleSer: 1.52 ± 1.043
4.559IleThr: 4.559 ± 1.167
0.76IleVal: 0.76 ± 0.743
1.52IleTrp: 1.52 ± 0.616
2.28IleTyr: 2.28 ± 0.997
0.0IleXaa: 0.0 ± 0.0
Lys
10.638LysAla: 10.638 ± 6.724
1.52LysCys: 1.52 ± 1.486
3.799LysAsp: 3.799 ± 1.435
8.359LysGlu: 8.359 ± 3.678
2.28LysPhe: 2.28 ± 1.565
2.28LysGly: 2.28 ± 0.832
0.76LysHis: 0.76 ± 0.522
3.799LysIle: 3.799 ± 1.027
5.319LysLys: 5.319 ± 2.862
1.52LysLeu: 1.52 ± 0.693
1.52LysMet: 1.52 ± 1.353
2.28LysAsn: 2.28 ± 0.568
1.52LysPro: 1.52 ± 1.043
2.28LysGln: 2.28 ± 1.441
5.319LysArg: 5.319 ± 3.492
0.76LysSer: 0.76 ± 0.522
2.28LysThr: 2.28 ± 1.846
9.878LysVal: 9.878 ± 5.946
0.76LysTrp: 0.76 ± 0.716
4.559LysTyr: 4.559 ± 1.136
0.0LysXaa: 0.0 ± 0.0
Leu
5.319LeuAla: 5.319 ± 2.23
0.0LeuCys: 0.0 ± 0.0
3.04LeuAsp: 3.04 ± 1.227
2.28LeuGlu: 2.28 ± 1.828
3.799LeuPhe: 3.799 ± 1.41
7.599LeuGly: 7.599 ± 2.835
0.0LeuHis: 0.0 ± 0.0
0.0LeuIle: 0.0 ± 0.0
1.52LeuLys: 1.52 ± 0.894
1.52LeuLeu: 1.52 ± 0.693
6.079LeuMet: 6.079 ± 3.2
7.599LeuAsn: 7.599 ± 2.021
7.599LeuPro: 7.599 ± 2.119
5.319LeuGln: 5.319 ± 1.488
4.559LeuArg: 4.559 ± 1.19
4.559LeuSer: 4.559 ± 1.847
3.799LeuThr: 3.799 ± 1.494
4.559LeuVal: 4.559 ± 1.347
0.76LeuTrp: 0.76 ± 0.522
0.76LeuTyr: 0.76 ± 0.522
0.0LeuXaa: 0.0 ± 0.0
Met
1.52MetAla: 1.52 ± 0.693
0.0MetCys: 0.0 ± 0.0
0.76MetAsp: 0.76 ± 0.522
3.04MetGlu: 3.04 ± 1.387
1.52MetPhe: 1.52 ± 0.616
0.76MetGly: 0.76 ± 0.522
0.0MetHis: 0.0 ± 0.0
0.76MetIle: 0.76 ± 0.716
4.559MetLys: 4.559 ± 1.657
3.04MetLeu: 3.04 ± 2.247
0.0MetMet: 0.0 ± 0.0
1.52MetAsn: 1.52 ± 1.043
1.52MetPro: 1.52 ± 1.043
3.04MetGln: 3.04 ± 1.817
3.799MetArg: 3.799 ± 1.813
6.079MetSer: 6.079 ± 1.809
3.799MetThr: 3.799 ± 1.636
1.52MetVal: 1.52 ± 0.616
0.0MetTrp: 0.0 ± 0.0
0.76MetTyr: 0.76 ± 0.716
0.0MetXaa: 0.0 ± 0.0
Asn
5.319AsnAla: 5.319 ± 0.962
0.76AsnCys: 0.76 ± 0.522
3.04AsnAsp: 3.04 ± 1.602
3.799AsnGlu: 3.799 ± 1.813
2.28AsnPhe: 2.28 ± 0.867
2.28AsnGly: 2.28 ± 1.285
0.0AsnHis: 0.0 ± 0.0
0.76AsnIle: 0.76 ± 0.522
4.559AsnLys: 4.559 ± 2.96
3.04AsnLeu: 3.04 ± 1.387
2.28AsnMet: 2.28 ± 1.2
0.76AsnAsn: 0.76 ± 0.522
3.799AsnPro: 3.799 ± 1.404
0.76AsnGln: 0.76 ± 0.716
4.559AsnArg: 4.559 ± 1.029
0.76AsnSer: 0.76 ± 0.522
1.52AsnThr: 1.52 ± 1.043
6.839AsnVal: 6.839 ± 1.077
0.0AsnTrp: 0.0 ± 0.0
0.76AsnTyr: 0.76 ± 0.743
0.0AsnXaa: 0.0 ± 0.0
Pro
2.28ProAla: 2.28 ± 0.867
0.76ProCys: 0.76 ± 0.743
3.799ProAsp: 3.799 ± 1.917
3.04ProGlu: 3.04 ± 1.089
0.76ProPhe: 0.76 ± 0.716
1.52ProGly: 1.52 ± 1.077
1.52ProHis: 1.52 ± 1.486
4.559ProIle: 4.559 ± 1.469
3.04ProLys: 3.04 ± 1.788
3.04ProLeu: 3.04 ± 1.602
0.0ProMet: 0.0 ± 0.0
4.559ProAsn: 4.559 ± 1.167
2.28ProPro: 2.28 ± 1.565
2.28ProGln: 2.28 ± 0.568
0.76ProArg: 0.76 ± 0.743
3.799ProSer: 3.799 ± 1.84
2.28ProThr: 2.28 ± 1.285
3.04ProVal: 3.04 ± 0.876
3.04ProTrp: 3.04 ± 2.087
1.52ProTyr: 1.52 ± 1.043
0.0ProXaa: 0.0 ± 0.0
Gln
3.04GlnAla: 3.04 ± 2.433
0.0GlnCys: 0.0 ± 0.0
2.28GlnAsp: 2.28 ± 0.997
3.799GlnGlu: 3.799 ± 1.955
0.0GlnPhe: 0.0 ± 0.0
2.28GlnGly: 2.28 ± 1.44
0.76GlnHis: 0.76 ± 0.716
0.76GlnIle: 0.76 ± 0.716
6.079GlnLys: 6.079 ± 2.201
1.52GlnLeu: 1.52 ± 0.616
1.52GlnMet: 1.52 ± 1.432
2.28GlnAsn: 2.28 ± 2.148
1.52GlnPro: 1.52 ± 1.132
2.28GlnGln: 2.28 ± 1.2
3.04GlnArg: 3.04 ± 1.387
3.799GlnSer: 3.799 ± 1.186
0.76GlnThr: 0.76 ± 0.716
3.04GlnVal: 3.04 ± 1.895
1.52GlnTrp: 1.52 ± 1.385
3.04GlnTyr: 3.04 ± 1.878
0.0GlnXaa: 0.0 ± 0.0
Arg
4.559ArgAla: 4.559 ± 1.627
0.0ArgCys: 0.0 ± 0.0
3.04ArgAsp: 3.04 ± 0.625
3.04ArgGlu: 3.04 ± 3.076
3.04ArgPhe: 3.04 ± 0.876
3.04ArgGly: 3.04 ± 0.625
1.52ArgHis: 1.52 ± 1.486
3.799ArgIle: 3.799 ± 0.881
4.559ArgLys: 4.559 ± 1.43
7.599ArgLeu: 7.599 ± 1.587
3.04ArgMet: 3.04 ± 1.291
3.799ArgAsn: 3.799 ± 1.287
0.76ArgPro: 0.76 ± 0.743
0.76ArgGln: 0.76 ± 0.716
3.04ArgArg: 3.04 ± 1.878
3.04ArgSer: 3.04 ± 1.291
2.28ArgThr: 2.28 ± 0.867
3.04ArgVal: 3.04 ± 1.126
0.76ArgTrp: 0.76 ± 0.743
4.559ArgTyr: 4.559 ± 1.847
0.0ArgXaa: 0.0 ± 0.0
Ser
5.319SerAla: 5.319 ± 2.854
0.0SerCys: 0.0 ± 0.0
3.799SerAsp: 3.799 ± 1.84
6.079SerGlu: 6.079 ± 2.181
3.04SerPhe: 3.04 ± 1.126
3.799SerGly: 3.799 ± 1.636
3.799SerHis: 3.799 ± 1.178
4.559SerIle: 4.559 ± 1.598
3.799SerLys: 3.799 ± 2.223
6.079SerLeu: 6.079 ± 0.944
2.28SerMet: 2.28 ± 1.085
1.52SerAsn: 1.52 ± 1.486
3.799SerPro: 3.799 ± 0.502
1.52SerGln: 1.52 ± 0.693
4.559SerArg: 4.559 ± 1.733
2.28SerSer: 2.28 ± 0.997
1.52SerThr: 1.52 ± 1.043
3.799SerVal: 3.799 ± 0.944
1.52SerTrp: 1.52 ± 0.616
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.799ThrAla: 3.799 ± 2.199
0.0ThrCys: 0.0 ± 0.0
2.28ThrAsp: 2.28 ± 0.568
6.079ThrGlu: 6.079 ± 1.576
3.04ThrPhe: 3.04 ± 1.45
4.559ThrGly: 4.559 ± 0.654
0.76ThrHis: 0.76 ± 0.522
1.52ThrIle: 1.52 ± 1.043
2.28ThrLys: 2.28 ± 1.2
3.04ThrLeu: 3.04 ± 1.976
0.0ThrMet: 0.0 ± 0.0
2.28ThrAsn: 2.28 ± 1.441
2.28ThrPro: 2.28 ± 1.2
1.52ThrGln: 1.52 ± 0.616
3.04ThrArg: 3.04 ± 0.876
5.319ThrSer: 5.319 ± 2.913
2.28ThrThr: 2.28 ± 1.085
4.559ThrVal: 4.559 ± 3.13
0.76ThrTrp: 0.76 ± 0.743
3.04ThrTyr: 3.04 ± 1.137
0.0ThrXaa: 0.0 ± 0.0
Val
5.319ValAla: 5.319 ± 1.947
0.76ValCys: 0.76 ± 0.743
6.839ValAsp: 6.839 ± 1.358
4.559ValGlu: 4.559 ± 0.776
2.28ValPhe: 2.28 ± 0.867
2.28ValGly: 2.28 ± 0.867
3.04ValHis: 3.04 ± 1.291
3.04ValIle: 3.04 ± 1.513
3.799ValLys: 3.799 ± 1.545
2.28ValLeu: 2.28 ± 1.565
2.28ValMet: 2.28 ± 1.565
1.52ValAsn: 1.52 ± 0.616
7.599ValPro: 7.599 ± 1.858
3.799ValGln: 3.799 ± 2.72
4.559ValArg: 4.559 ± 1.947
5.319ValSer: 5.319 ± 1.547
6.079ValThr: 6.079 ± 2.252
3.799ValVal: 3.799 ± 2.365
0.76ValTrp: 0.76 ± 0.743
2.28ValTyr: 2.28 ± 0.867
0.0ValXaa: 0.0 ± 0.0
Trp
2.28TrpAla: 2.28 ± 0.568
0.76TrpCys: 0.76 ± 0.522
0.76TrpAsp: 0.76 ± 0.98
0.76TrpGlu: 0.76 ± 0.522
0.76TrpPhe: 0.76 ± 0.716
0.76TrpGly: 0.76 ± 0.522
1.52TrpHis: 1.52 ± 0.616
0.0TrpIle: 0.0 ± 0.0
2.28TrpLys: 2.28 ± 0.997
0.76TrpLeu: 0.76 ± 0.522
2.28TrpMet: 2.28 ± 1.2
0.0TrpAsn: 0.0 ± 0.0
2.28TrpPro: 2.28 ± 1.261
0.76TrpGln: 0.76 ± 0.716
0.76TrpArg: 0.76 ± 0.743
1.52TrpSer: 1.52 ± 0.616
3.04TrpThr: 3.04 ± 1.231
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.76TrpTyr: 0.76 ± 0.522
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.52TyrAla: 1.52 ± 0.616
0.0TyrCys: 0.0 ± 0.0
2.28TyrAsp: 2.28 ± 1.31
1.52TyrGlu: 1.52 ± 0.893
0.76TyrPhe: 0.76 ± 0.522
3.799TyrGly: 3.799 ± 1.334
1.52TyrHis: 1.52 ± 0.616
0.76TyrIle: 0.76 ± 0.743
4.559TyrLys: 4.559 ± 1.029
3.799TyrLeu: 3.799 ± 0.944
2.28TyrMet: 2.28 ± 0.568
2.28TyrAsn: 2.28 ± 0.568
1.52TyrPro: 1.52 ± 0.616
3.799TyrGln: 3.799 ± 1.636
2.28TyrArg: 2.28 ± 1.565
3.799TyrSer: 3.799 ± 1.41
0.76TyrThr: 0.76 ± 0.743
1.52TyrVal: 1.52 ± 0.693
0.76TyrTrp: 0.76 ± 0.98
3.04TyrTyr: 3.04 ± 1.231
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1317 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski