Amino acid dipepetide frequency for Planifilum fulgidum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.914AlaAla: 8.914 ± 0.126	0.837AlaCys: 0.837 ± 0.034	4.347AlaAsp: 4.347 ± 0.075	6.807AlaGlu: 6.807 ± 0.096	3.645AlaPhe: 3.645 ± 0.073	7.735AlaGly: 7.735 ± 0.104	1.563AlaHis: 1.563 ± 0.039	4.804AlaIle: 4.804 ± 0.063	3.806AlaLys: 3.806 ± 0.071	9.535AlaLeu: 9.535 ± 0.125	2.26AlaMet: 2.26 ± 0.043	1.715AlaAsn: 1.715 ± 0.036	3.057AlaPro: 3.057 ± 0.059	2.094AlaGln: 2.094 ± 0.052	6.041AlaArg: 6.041 ± 0.083	4.206AlaSer: 4.206 ± 0.068	3.223AlaThr: 3.223 ± 0.058	8.004AlaVal: 8.004 ± 0.1	1.03AlaTrp: 1.03 ± 0.036	2.313AlaTyr: 2.313 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.629CysAla: 0.629 ± 0.027	0.111CysCys: 0.111 ± 0.014	0.494CysAsp: 0.494 ± 0.023	0.384CysGlu: 0.384 ± 0.022	0.354CysPhe: 0.354 ± 0.02	0.975CysGly: 0.975 ± 0.028	0.24CysHis: 0.24 ± 0.019	0.423CysIle: 0.423 ± 0.016	0.212CysLys: 0.212 ± 0.015	0.901CysLeu: 0.901 ± 0.028	0.148CysMet: 0.148 ± 0.013	0.219CysAsn: 0.219 ± 0.015	0.53CysPro: 0.53 ± 0.023	0.2CysGln: 0.2 ± 0.013	0.827CysArg: 0.827 ± 0.036	0.485CysSer: 0.485 ± 0.025	0.403CysThr: 0.403 ± 0.02	0.481CysVal: 0.481 ± 0.025	0.113CysTrp: 0.113 ± 0.011	0.246CysTyr: 0.246 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.942AspAla: 3.942 ± 0.07	0.364AspCys: 0.364 ± 0.019	2.026AspAsp: 2.026 ± 0.048	3.927AspGlu: 3.927 ± 0.068	1.999AspPhe: 1.999 ± 0.049	4.034AspGly: 4.034 ± 0.075	1.174AspHis: 1.174 ± 0.039	2.563AspIle: 2.563 ± 0.049	1.879AspLys: 1.879 ± 0.05	5.343AspLeu: 5.343 ± 0.082	1.088AspMet: 1.088 ± 0.032	1.045AspAsn: 1.045 ± 0.036	3.479AspPro: 3.479 ± 0.062	1.57AspGln: 1.57 ± 0.04	4.558AspArg: 4.558 ± 0.075	2.064AspSer: 2.064 ± 0.051	1.812AspThr: 1.812 ± 0.05	3.842AspVal: 3.842 ± 0.066	0.859AspTrp: 0.859 ± 0.033	1.435AspTyr: 1.435 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	7.22GluAla: 7.22 ± 0.107	0.435GluCys: 0.435 ± 0.024	3.399GluAsp: 3.399 ± 0.064	8.198GluGlu: 8.198 ± 0.123	1.756GluPhe: 1.756 ± 0.043	5.996GluGly: 5.996 ± 0.087	1.396GluHis: 1.396 ± 0.04	4.49GluIle: 4.49 ± 0.077	5.475GluLys: 5.475 ± 0.089	6.462GluLeu: 6.462 ± 0.099	2.279GluMet: 2.279 ± 0.047	2.197GluAsn: 2.197 ± 0.049	2.662GluPro: 2.662 ± 0.047	2.719GluGln: 2.719 ± 0.063	6.489GluArg: 6.489 ± 0.114	3.135GluSer: 3.135 ± 0.052	3.621GluThr: 3.621 ± 0.059	5.431GluVal: 5.431 ± 0.089	1.169GluTrp: 1.169 ± 0.041	1.754GluTyr: 1.754 ± 0.052	0.0GluXaa: 0.0 ± 0.0
Phe	3.382PheAla: 3.382 ± 0.067	0.408PheCys: 0.408 ± 0.018	2.163PheAsp: 2.163 ± 0.049	2.09PheGlu: 2.09 ± 0.048	2.101PhePhe: 2.101 ± 0.061	3.374PheGly: 3.374 ± 0.069	0.945PheHis: 0.945 ± 0.033	1.97PheIle: 1.97 ± 0.048	1.16PheLys: 1.16 ± 0.037	4.644PheLeu: 4.644 ± 0.078	0.747PheMet: 0.747 ± 0.031	0.971PheAsn: 0.971 ± 0.034	2.135PhePro: 2.135 ± 0.047	1.255PheGln: 1.255 ± 0.033	3.139PheArg: 3.139 ± 0.058	2.634PheSer: 2.634 ± 0.063	1.904PheThr: 1.904 ± 0.045	3.004PheVal: 3.004 ± 0.057	0.569PheTrp: 0.569 ± 0.027	1.236PheTyr: 1.236 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	6.398GlyAla: 6.398 ± 0.102	0.87GlyCys: 0.87 ± 0.032	3.881GlyAsp: 3.881 ± 0.059	6.085GlyGlu: 6.085 ± 0.089	3.36GlyPhe: 3.36 ± 0.064	6.787GlyGly: 6.787 ± 0.095	1.566GlyHis: 1.566 ± 0.043	5.599GlyIle: 5.599 ± 0.086	5.101GlyLys: 5.101 ± 0.081	8.033GlyLeu: 8.033 ± 0.113	2.784GlyMet: 2.784 ± 0.058	2.229GlyAsn: 2.229 ± 0.052	2.887GlyPro: 2.887 ± 0.061	2.186GlyGln: 2.186 ± 0.049	5.869GlyArg: 5.869 ± 0.087	4.209GlySer: 4.209 ± 0.073	4.329GlyThr: 4.329 ± 0.085	6.186GlyVal: 6.186 ± 0.083	1.464GlyTrp: 1.464 ± 0.048	2.539GlyTyr: 2.539 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.596HisAla: 1.596 ± 0.043	0.214HisCys: 0.214 ± 0.017	0.786HisAsp: 0.786 ± 0.032	1.038HisGlu: 1.038 ± 0.037	1.043HisPhe: 1.043 ± 0.033	1.605HisGly: 1.605 ± 0.048	0.632HisHis: 0.632 ± 0.035	1.116HisIle: 1.116 ± 0.038	0.601HisLys: 0.601 ± 0.023	2.694HisLeu: 2.694 ± 0.062	0.43HisMet: 0.43 ± 0.023	0.466HisAsn: 0.466 ± 0.023	1.848HisPro: 1.848 ± 0.054	0.67HisGln: 0.67 ± 0.025	2.003HisArg: 2.003 ± 0.049	0.968HisSer: 0.968 ± 0.031	0.906HisThr: 0.906 ± 0.03	1.471HisVal: 1.471 ± 0.039	0.305HisTrp: 0.305 ± 0.017	0.659HisTyr: 0.659 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.615IleAla: 5.615 ± 0.09	0.519IleCys: 0.519 ± 0.02	3.131IleAsp: 3.131 ± 0.056	3.495IleGlu: 3.495 ± 0.063	2.049IlePhe: 2.049 ± 0.054	5.138IleGly: 5.138 ± 0.086	1.479IleHis: 1.479 ± 0.037	2.846IleIle: 2.846 ± 0.06	1.935IleLys: 1.935 ± 0.047	6.243IleLeu: 6.243 ± 0.094	1.09IleMet: 1.09 ± 0.037	1.573IleAsn: 1.573 ± 0.038	3.51IlePro: 3.51 ± 0.072	1.908IleGln: 1.908 ± 0.045	5.494IleArg: 5.494 ± 0.086	3.027IleSer: 3.027 ± 0.052	2.748IleThr: 2.748 ± 0.055	4.144IleVal: 4.144 ± 0.079	0.601IleTrp: 0.601 ± 0.024	1.659IleTyr: 1.659 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.068LysAla: 4.068 ± 0.068	0.267LysCys: 0.267 ± 0.017	2.263LysAsp: 2.263 ± 0.06	4.757LysGlu: 4.757 ± 0.084	0.953LysPhe: 0.953 ± 0.038	4.216LysGly: 4.216 ± 0.082	0.918LysHis: 0.918 ± 0.028	2.581LysIle: 2.581 ± 0.056	3.456LysLys: 3.456 ± 0.07	3.789LysLeu: 3.789 ± 0.073	1.5LysMet: 1.5 ± 0.045	1.608LysAsn: 1.608 ± 0.049	2.311LysPro: 2.311 ± 0.049	1.628LysGln: 1.628 ± 0.045	4.121LysArg: 4.121 ± 0.065	2.082LysSer: 2.082 ± 0.049	2.418LysThr: 2.418 ± 0.05	3.527LysVal: 3.527 ± 0.066	0.785LysTrp: 0.785 ± 0.031	1.271LysTyr: 1.271 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	9.564LeuAla: 9.564 ± 0.123	0.908LeuCys: 0.908 ± 0.03	5.113LeuAsp: 5.113 ± 0.079	7.328LeuGlu: 7.328 ± 0.102	4.892LeuPhe: 4.892 ± 0.09	7.63LeuGly: 7.63 ± 0.107	2.129LeuHis: 2.129 ± 0.045	6.424LeuIle: 6.424 ± 0.103	5.392LeuLys: 5.392 ± 0.084	11.83LeuLeu: 11.83 ± 0.147	2.464LeuMet: 2.464 ± 0.055	2.685LeuAsn: 2.685 ± 0.051	5.262LeuPro: 5.262 ± 0.079	2.796LeuGln: 2.796 ± 0.058	7.233LeuArg: 7.233 ± 0.104	6.835LeuSer: 6.835 ± 0.078	5.164LeuThr: 5.164 ± 0.073	7.291LeuVal: 7.291 ± 0.115	1.342LeuTrp: 1.342 ± 0.041	2.917LeuTyr: 2.917 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.437MetAla: 2.437 ± 0.054	0.149MetCys: 0.149 ± 0.011	1.445MetAsp: 1.445 ± 0.037	2.24MetGlu: 2.24 ± 0.044	0.853MetPhe: 0.853 ± 0.032	2.072MetGly: 2.072 ± 0.051	0.407MetHis: 0.407 ± 0.021	1.678MetIle: 1.678 ± 0.044	1.696MetLys: 1.696 ± 0.04	2.304MetLeu: 2.304 ± 0.051	0.747MetMet: 0.747 ± 0.035	0.939MetAsn: 0.939 ± 0.032	1.055MetPro: 1.055 ± 0.037	0.673MetGln: 0.673 ± 0.028	1.725MetArg: 1.725 ± 0.038	1.315MetSer: 1.315 ± 0.041	1.411MetThr: 1.411 ± 0.037	1.936MetVal: 1.936 ± 0.04	0.243MetTrp: 0.243 ± 0.017	0.56MetTyr: 0.56 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	1.976AsnAla: 1.976 ± 0.042	0.226AsnCys: 0.226 ± 0.015	1.088AsnAsp: 1.088 ± 0.034	1.585AsnGlu: 1.585 ± 0.042	0.857AsnPhe: 0.857 ± 0.029	2.055AsnGly: 2.055 ± 0.049	0.586AsnHis: 0.586 ± 0.026	1.521AsnIle: 1.521 ± 0.046	1.041AsnLys: 1.041 ± 0.036	2.796AsnLeu: 2.796 ± 0.048	0.641AsnMet: 0.641 ± 0.024	0.722AsnAsn: 0.722 ± 0.037	1.962AsnPro: 1.962 ± 0.047	1.006AsnGln: 1.006 ± 0.04	2.676AsnArg: 2.676 ± 0.06	1.076AsnSer: 1.076 ± 0.034	1.115AsnThr: 1.115 ± 0.04	1.836AsnVal: 1.836 ± 0.049	0.409AsnTrp: 0.409 ± 0.018	0.741AsnTyr: 0.741 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	3.901ProAla: 3.901 ± 0.064	0.359ProCys: 0.359 ± 0.019	3.139ProAsp: 3.139 ± 0.053	4.799ProGlu: 4.799 ± 0.076	2.229ProPhe: 2.229 ± 0.043	4.312ProGly: 4.312 ± 0.071	1.143ProHis: 1.143 ± 0.033	2.331ProIle: 2.331 ± 0.051	2.05ProLys: 2.05 ± 0.052	4.918ProLeu: 4.918 ± 0.084	1.079ProMet: 1.079 ± 0.035	1.059ProAsn: 1.059 ± 0.034	2.312ProPro: 2.312 ± 0.057	1.227ProGln: 1.227 ± 0.038	2.966ProArg: 2.966 ± 0.061	2.754ProSer: 2.754 ± 0.054	1.883ProThr: 1.883 ± 0.041	4.513ProVal: 4.513 ± 0.086	0.712ProTrp: 0.712 ± 0.031	1.418ProTyr: 1.418 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	2.805GlnAla: 2.805 ± 0.057	0.187GlnCys: 0.187 ± 0.013	1.123GlnAsp: 1.123 ± 0.039	2.092GlnGlu: 2.092 ± 0.054	1.012GlnPhe: 1.012 ± 0.034	2.204GlnGly: 2.204 ± 0.049	0.54GlnHis: 0.54 ± 0.024	1.836GlnIle: 1.836 ± 0.045	1.577GlnLys: 1.577 ± 0.036	3.047GlnLeu: 3.047 ± 0.057	0.921GlnMet: 0.921 ± 0.039	0.84GlnAsn: 0.84 ± 0.029	1.343GlnPro: 1.343 ± 0.047	1.113GlnGln: 1.113 ± 0.036	2.04GlnArg: 2.04 ± 0.051	1.494GlnSer: 1.494 ± 0.038	1.396GlnThr: 1.396 ± 0.037	2.462GlnVal: 2.462 ± 0.058	0.441GlnTrp: 0.441 ± 0.023	0.775GlnTyr: 0.775 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	5.365ArgAla: 5.365 ± 0.085	0.597ArgCys: 0.597 ± 0.027	3.639ArgAsp: 3.639 ± 0.067	7.01ArgGlu: 7.01 ± 0.098	3.445ArgPhe: 3.445 ± 0.062	5.275ArgGly: 5.275 ± 0.084	1.737ArgHis: 1.737 ± 0.048	5.089ArgIle: 5.089 ± 0.079	4.167ArgLys: 4.167 ± 0.065	8.842ArgLeu: 8.842 ± 0.118	2.336ArgMet: 2.336 ± 0.053	1.969ArgAsn: 1.969 ± 0.047	3.429ArgPro: 3.429 ± 0.07	2.412ArgGln: 2.412 ± 0.059	7.213ArgArg: 7.213 ± 0.119	3.691ArgSer: 3.691 ± 0.071	3.144ArgThr: 3.144 ± 0.056	5.642ArgVal: 5.642 ± 0.093	1.348ArgTrp: 1.348 ± 0.035	2.302ArgTyr: 2.302 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	4.23SerAla: 4.23 ± 0.064	0.437SerCys: 0.437 ± 0.019	2.438SerAsp: 2.438 ± 0.051	3.165SerGlu: 3.165 ± 0.055	2.516SerPhe: 2.516 ± 0.058	5.177SerGly: 5.177 ± 0.083	1.11SerHis: 1.11 ± 0.04	2.666SerIle: 2.666 ± 0.05	1.921SerLys: 1.921 ± 0.049	5.935SerLeu: 5.935 ± 0.085	1.317SerMet: 1.317 ± 0.037	1.154SerAsn: 1.154 ± 0.036	2.95SerPro: 2.95 ± 0.06	1.291SerGln: 1.291 ± 0.038	4.181SerArg: 4.181 ± 0.071	2.866SerSer: 2.866 ± 0.06	2.143SerThr: 2.143 ± 0.045	3.928SerVal: 3.928 ± 0.069	0.715SerTrp: 0.715 ± 0.029	1.288SerTyr: 1.288 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	4.235ThrAla: 4.235 ± 0.074	0.373ThrCys: 0.373 ± 0.02	2.304ThrAsp: 2.304 ± 0.054	2.848ThrGlu: 2.848 ± 0.053	1.928ThrPhe: 1.928 ± 0.047	4.818ThrGly: 4.818 ± 0.069	0.942ThrHis: 0.942 ± 0.036	2.66ThrIle: 2.66 ± 0.056	1.534ThrLys: 1.534 ± 0.039	5.047ThrLeu: 5.047 ± 0.078	1.069ThrMet: 1.069 ± 0.033	1.107ThrAsn: 1.107 ± 0.034	2.58ThrPro: 2.58 ± 0.049	0.994ThrGln: 0.994 ± 0.033	2.866ThrArg: 2.866 ± 0.059	2.172ThrSer: 2.172 ± 0.055	2.017ThrThr: 2.017 ± 0.049	4.332ThrVal: 4.332 ± 0.066	0.552ThrTrp: 0.552 ± 0.023	1.377ThrTyr: 1.377 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	6.398ValAla: 6.398 ± 0.081	0.715ValCys: 0.715 ± 0.025	4.064ValAsp: 4.064 ± 0.067	5.655ValGlu: 5.655 ± 0.093	3.022ValPhe: 3.022 ± 0.063	5.522ValGly: 5.522 ± 0.082	1.572ValHis: 1.572 ± 0.039	5.133ValIle: 5.133 ± 0.083	3.727ValLys: 3.727 ± 0.071	8.002ValLeu: 8.002 ± 0.114	1.851ValMet: 1.851 ± 0.046	2.132ValAsn: 2.132 ± 0.052	3.795ValPro: 3.795 ± 0.063	2.164ValGln: 2.164 ± 0.046	5.692ValArg: 5.692 ± 0.091	4.413ValSer: 4.413 ± 0.069	4.116ValThr: 4.116 ± 0.07	6.023ValVal: 6.023 ± 0.089	0.956ValTrp: 0.956 ± 0.034	2.118ValTyr: 2.118 ± 0.053	0.0ValXaa: 0.0 ± 0.0
Trp	0.977TrpAla: 0.977 ± 0.035	0.113TrpCys: 0.113 ± 0.01	0.662TrpAsp: 0.662 ± 0.027	1.009TrpGlu: 1.009 ± 0.037	0.609TrpPhe: 0.609 ± 0.029	1.037TrpGly: 1.037 ± 0.038	0.251TrpHis: 0.251 ± 0.017	1.068TrpIle: 1.068 ± 0.035	0.813TrpLys: 0.813 ± 0.029	1.66TrpLeu: 1.66 ± 0.042	0.557TrpMet: 0.557 ± 0.023	0.531TrpAsn: 0.531 ± 0.025	0.499TrpPro: 0.499 ± 0.027	0.419TrpGln: 0.419 ± 0.026	0.914TrpArg: 0.914 ± 0.028	0.732TrpSer: 0.732 ± 0.033	0.727TrpThr: 0.727 ± 0.029	1.06TrpVal: 1.06 ± 0.035	0.256TrpTrp: 0.256 ± 0.018	0.358TrpTyr: 0.358 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.283TyrAla: 2.283 ± 0.051	0.286TyrCys: 0.286 ± 0.019	1.497TyrAsp: 1.497 ± 0.05	1.769TyrGlu: 1.769 ± 0.046	1.21TyrPhe: 1.21 ± 0.036	2.4TyrGly: 2.4 ± 0.051	0.719TyrHis: 0.719 ± 0.029	1.405TyrIle: 1.405 ± 0.044	0.974TyrLys: 0.974 ± 0.037	3.174TyrLeu: 3.174 ± 0.059	0.578TyrMet: 0.578 ± 0.023	0.758TyrAsn: 0.758 ± 0.032	1.499TyrPro: 1.499 ± 0.045	0.925TyrGln: 0.925 ± 0.034	2.605TyrArg: 2.605 ± 0.055	1.271TyrSer: 1.271 ± 0.033	1.275TyrThr: 1.275 ± 0.04	1.955TyrVal: 1.955 ± 0.041	0.383TyrTrp: 0.383 ± 0.021	0.97TyrTyr: 0.97 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3217 proteins (940472 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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