Amino acid dipepetide frequency for Wenling crustacean virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.51AlaAla: 5.51 ± 0.991
1.837AlaCys: 1.837 ± 1.1
3.061AlaAsp: 3.061 ± 0.159
4.897AlaGlu: 4.897 ± 1.683
3.979AlaPhe: 3.979 ± 0.874
3.061AlaGly: 3.061 ± 0.159
1.224AlaHis: 1.224 ± 0.306
2.449AlaIle: 2.449 ± 0.503
3.673AlaLys: 3.673 ± 0.856
6.734AlaLeu: 6.734 ± 1.422
2.143AlaMet: 2.143 ± 0.86
4.285AlaAsn: 4.285 ± 0.82
4.591AlaPro: 4.591 ± 1.618
3.673AlaGln: 3.673 ± 0.36
4.897AlaArg: 4.897 ± 1.253
3.673AlaSer: 3.673 ± 1.338
6.734AlaThr: 6.734 ± 1.155
4.591AlaVal: 4.591 ± 0.719
0.612AlaTrp: 0.612 ± 0.367
2.755AlaTyr: 2.755 ± 0.744
0.0AlaXaa: 0.0 ± 0.0
Cys
1.224CysAla: 1.224 ± 0.336
0.0CysCys: 0.0 ± 0.0
1.224CysAsp: 1.224 ± 0.503
0.612CysGlu: 0.612 ± 0.367
1.224CysPhe: 1.224 ± 0.733
0.306CysGly: 0.306 ± 0.183
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.918CysLys: 0.918 ± 0.186
1.53CysLeu: 1.53 ± 0.508
0.918CysMet: 0.918 ± 0.55
0.612CysAsn: 0.612 ± 0.367
0.918CysPro: 0.918 ± 0.186
1.224CysGln: 1.224 ± 0.306
1.224CysArg: 1.224 ± 0.733
1.224CysSer: 1.224 ± 0.733
0.612CysThr: 0.612 ± 0.367
0.918CysVal: 0.918 ± 0.55
0.306CysTrp: 0.306 ± 0.282
0.612CysTyr: 0.612 ± 0.367
0.0CysXaa: 0.0 ± 0.0
Asp
3.367AspAla: 3.367 ± 1.057
0.612AspCys: 0.612 ± 0.153
3.061AspAsp: 3.061 ± 0.765
2.143AspGlu: 2.143 ± 1.106
3.367AspPhe: 3.367 ± 1.005
2.143AspGly: 2.143 ± 0.846
3.061AspHis: 3.061 ± 0.692
3.673AspIle: 3.673 ± 0.469
1.224AspLys: 1.224 ± 0.336
4.897AspLeu: 4.897 ± 0.563
0.918AspMet: 0.918 ± 0.361
3.367AspAsn: 3.367 ± 0.638
4.285AspPro: 4.285 ± 2.12
2.143AspGln: 2.143 ± 0.401
2.755AspArg: 2.755 ± 0.857
3.367AspSer: 3.367 ± 0.614
4.897AspThr: 4.897 ± 0.048
3.367AspVal: 3.367 ± 0.769
0.612AspTrp: 0.612 ± 0.367
2.449AspTyr: 2.449 ± 0.971
0.0AspXaa: 0.0 ± 0.0
Glu
3.673GluAla: 3.673 ± 1.777
1.224GluCys: 1.224 ± 0.503
3.367GluAsp: 3.367 ± 0.595
3.673GluGlu: 3.673 ± 2.2
2.143GluPhe: 2.143 ± 0.514
4.285GluGly: 4.285 ± 1.733
3.673GluHis: 3.673 ± 0.703
3.367GluIle: 3.367 ± 1.06
2.449GluLys: 2.449 ± 0.672
5.51GluLeu: 5.51 ± 0.111
0.918GluMet: 0.918 ± 0.415
2.449GluAsn: 2.449 ± 0.669
3.673GluPro: 3.673 ± 0.951
2.755GluGln: 2.755 ± 0.408
4.285GluArg: 4.285 ± 0.886
2.449GluSer: 2.449 ± 0.971
3.367GluThr: 3.367 ± 0.595
3.673GluVal: 3.673 ± 0.521
0.612GluTrp: 0.612 ± 0.367
1.53GluTyr: 1.53 ± 0.64
0.0GluXaa: 0.0 ± 0.0
Phe
2.449PheAla: 2.449 ± 0.694
0.306PheCys: 0.306 ± 0.183
3.367PheAsp: 3.367 ± 0.638
3.061PheGlu: 3.061 ± 0.588
1.224PhePhe: 1.224 ± 0.693
2.449PheGly: 2.449 ± 1.119
2.143PheHis: 2.143 ± 0.42
3.367PheIle: 3.367 ± 0.339
1.837PheLys: 1.837 ± 1.1
3.367PheLeu: 3.367 ± 0.845
0.306PheMet: 0.306 ± 0.282
1.224PheAsn: 1.224 ± 0.693
2.143PhePro: 2.143 ± 0.42
2.755PheGln: 2.755 ± 0.54
1.837PheArg: 1.837 ± 0.583
4.285PheSer: 4.285 ± 1.8
3.367PheThr: 3.367 ± 1.799
2.449PheVal: 2.449 ± 0.971
0.0PheTrp: 0.0 ± 0.0
0.918PheTyr: 0.918 ± 0.404
0.0PheXaa: 0.0 ± 0.0
Gly
5.816GlyAla: 5.816 ± 1.217
0.918GlyCys: 0.918 ± 0.55
4.591GlyAsp: 4.591 ± 1.048
3.673GlyGlu: 3.673 ± 1.373
2.143GlyPhe: 2.143 ± 0.511
3.673GlyGly: 3.673 ± 0.469
2.143GlyHis: 2.143 ± 0.511
3.061GlyIle: 3.061 ± 1.412
3.367GlyLys: 3.367 ± 0.638
4.591GlyLeu: 4.591 ± 1.18
1.53GlyMet: 1.53 ± 0.349
2.755GlyAsn: 2.755 ± 0.842
3.061GlyPro: 3.061 ± 0.41
0.918GlyGln: 0.918 ± 0.186
3.367GlyArg: 3.367 ± 0.334
3.367GlySer: 3.367 ± 0.208
4.591GlyThr: 4.591 ± 1.553
3.673GlyVal: 3.673 ± 1.659
1.224GlyTrp: 1.224 ± 0.306
1.837GlyTyr: 1.837 ± 0.621
0.0GlyXaa: 0.0 ± 0.0
His
3.367HisAla: 3.367 ± 1.662
1.224HisCys: 1.224 ± 0.336
1.837HisAsp: 1.837 ± 0.459
2.449HisGlu: 2.449 ± 1.466
0.612HisPhe: 0.612 ± 0.153
2.449HisGly: 2.449 ± 1.048
1.53HisHis: 1.53 ± 0.287
2.143HisIle: 2.143 ± 0.42
1.837HisLys: 1.837 ± 0.686
3.367HisLeu: 3.367 ± 0.769
0.612HisMet: 0.612 ± 0.367
1.837HisAsn: 1.837 ± 0.372
2.449HisPro: 2.449 ± 1.024
1.224HisGln: 1.224 ± 0.336
1.53HisArg: 1.53 ± 0.287
3.061HisSer: 3.061 ± 0.333
5.204HisThr: 5.204 ± 0.665
1.837HisVal: 1.837 ± 0.459
0.612HisTrp: 0.612 ± 0.376
2.143HisTyr: 2.143 ± 0.867
0.0HisXaa: 0.0 ± 0.0
Ile
5.51IleAla: 5.51 ± 0.829
0.612IleCys: 0.612 ± 0.367
5.51IleAsp: 5.51 ± 1.376
3.367IleGlu: 3.367 ± 0.334
1.53IlePhe: 1.53 ± 0.287
5.816IleGly: 5.816 ± 1.122
3.673IleHis: 3.673 ± 0.951
3.367IleIle: 3.367 ± 0.334
2.755IleLys: 2.755 ± 0.557
3.367IleLeu: 3.367 ± 0.638
0.918IleMet: 0.918 ± 0.55
3.367IleAsn: 3.367 ± 1.05
2.755IlePro: 2.755 ± 0.877
2.449IleGln: 2.449 ± 0.233
1.837IleArg: 1.837 ± 0.809
4.897IleSer: 4.897 ± 1.126
3.979IleThr: 3.979 ± 0.361
2.143IleVal: 2.143 ± 0.962
0.306IleTrp: 0.306 ± 0.431
1.224IleTyr: 1.224 ± 0.252
0.0IleXaa: 0.0 ± 0.0
Lys
2.755LysAla: 2.755 ± 0.408
1.224LysCys: 1.224 ± 0.336
0.918LysAsp: 0.918 ± 0.186
2.755LysGlu: 2.755 ± 1.23
0.918LysPhe: 0.918 ± 0.55
3.367LysGly: 3.367 ± 0.769
2.449LysHis: 2.449 ± 0.233
3.061LysIle: 3.061 ± 1.484
1.837LysLys: 1.837 ± 0.796
3.061LysLeu: 3.061 ± 0.87
0.612LysMet: 0.612 ± 0.367
0.612LysAsn: 0.612 ± 0.367
3.367LysPro: 3.367 ± 0.208
0.918LysGln: 0.918 ± 0.55
2.143LysArg: 2.143 ± 0.612
1.837LysSer: 1.837 ± 0.372
2.143LysThr: 2.143 ± 0.612
1.224LysVal: 1.224 ± 0.336
0.0LysTrp: 0.0 ± 0.0
2.143LysTyr: 2.143 ± 0.099
0.0LysXaa: 0.0 ± 0.0
Leu
9.183LeuAla: 9.183 ± 0.578
1.224LeuCys: 1.224 ± 0.733
5.816LeuAsp: 5.816 ± 0.613
4.897LeuGlu: 4.897 ± 0.466
1.53LeuPhe: 1.53 ± 0.508
4.897LeuGly: 4.897 ± 0.563
5.204LeuHis: 5.204 ± 0.665
2.755LeuIle: 2.755 ± 0.557
4.897LeuLys: 4.897 ± 0.916
8.877LeuLeu: 8.877 ± 0.981
1.837LeuMet: 1.837 ± 0.614
3.979LeuAsn: 3.979 ± 0.225
5.816LeuPro: 5.816 ± 2.169
2.449LeuGln: 2.449 ± 0.669
4.591LeuArg: 4.591 ± 0.747
7.04LeuSer: 7.04 ± 1.586
6.122LeuThr: 6.122 ± 2.629
5.816LeuVal: 5.816 ± 0.395
0.306LeuTrp: 0.306 ± 0.282
2.755LeuTyr: 2.755 ± 0.564
0.0LeuXaa: 0.0 ± 0.0
Met
2.755MetAla: 2.755 ± 1.454
0.0MetCys: 0.0 ± 0.0
0.612MetAsp: 0.612 ± 0.153
0.306MetGlu: 0.306 ± 0.282
0.612MetPhe: 0.612 ± 0.564
1.224MetGly: 1.224 ± 0.336
0.306MetHis: 0.306 ± 0.282
1.224MetIle: 1.224 ± 0.252
0.612MetLys: 0.612 ± 0.367
2.143MetLeu: 2.143 ± 0.099
0.0MetMet: 0.0 ± 0.0
0.612MetAsn: 0.612 ± 0.564
0.918MetPro: 0.918 ± 0.709
1.837MetGln: 1.837 ± 0.686
2.143MetArg: 2.143 ± 1.283
2.449MetSer: 2.449 ± 0.694
1.224MetThr: 1.224 ± 0.503
1.53MetVal: 1.53 ± 0.64
0.306MetTrp: 0.306 ± 0.282
0.612MetTyr: 0.612 ± 0.153
0.0MetXaa: 0.0 ± 0.0
Asn
3.673AsnAla: 3.673 ± 1.607
0.918AsnCys: 0.918 ± 0.186
2.143AsnAsp: 2.143 ± 0.099
1.837AsnGlu: 1.837 ± 1.1
2.755AsnPhe: 2.755 ± 0.945
2.449AsnGly: 2.449 ± 0.683
2.143AsnHis: 2.143 ± 0.962
3.979AsnIle: 3.979 ± 0.361
0.306AsnLys: 0.306 ± 0.431
3.673AsnLeu: 3.673 ± 0.722
0.918AsnMet: 0.918 ± 0.404
2.143AsnAsn: 2.143 ± 0.401
1.53AsnPro: 1.53 ± 0.973
1.224AsnGln: 1.224 ± 0.503
2.449AsnArg: 2.449 ± 0.672
3.061AsnSer: 3.061 ± 1.521
4.897AsnThr: 4.897 ± 1.16
1.837AsnVal: 1.837 ± 0.18
0.306AsnTrp: 0.306 ± 0.282
1.224AsnTyr: 1.224 ± 0.751
0.0AsnXaa: 0.0 ± 0.0
Pro
3.673ProAla: 3.673 ± 0.35
0.918ProCys: 0.918 ± 0.55
3.673ProAsp: 3.673 ± 1.724
3.367ProGlu: 3.367 ± 0.843
3.979ProPhe: 3.979 ± 1.178
5.204ProGly: 5.204 ± 1.499
0.306ProHis: 0.306 ± 0.183
3.367ProIle: 3.367 ± 1.386
1.53ProLys: 1.53 ± 0.64
3.979ProLeu: 3.979 ± 1.564
1.837ProMet: 1.837 ± 0.178
2.449ProAsn: 2.449 ± 0.503
1.837ProPro: 1.837 ± 0.723
3.673ProGln: 3.673 ± 1.208
3.367ProArg: 3.367 ± 0.339
3.061ProSer: 3.061 ± 0.159
3.367ProThr: 3.367 ± 0.339
3.979ProVal: 3.979 ± 1.656
0.306ProTrp: 0.306 ± 0.183
1.224ProTyr: 1.224 ± 0.306
0.0ProXaa: 0.0 ± 0.0
Gln
1.224GlnAla: 1.224 ± 0.733
0.306GlnCys: 0.306 ± 0.282
1.837GlnAsp: 1.837 ± 0.361
2.755GlnGlu: 2.755 ± 1.23
3.061GlnPhe: 3.061 ± 1.521
2.449GlnGly: 2.449 ± 1.048
1.224GlnHis: 1.224 ± 0.781
2.755GlnIle: 2.755 ± 1.244
1.224GlnLys: 1.224 ± 0.751
4.897GlnLeu: 4.897 ± 0.513
0.612GlnMet: 0.612 ± 0.407
1.224GlnAsn: 1.224 ± 0.252
4.897GlnPro: 4.897 ± 0.048
0.918GlnGln: 0.918 ± 0.55
0.918GlnArg: 0.918 ± 0.415
3.367GlnSer: 3.367 ± 0.208
0.918GlnThr: 0.918 ± 0.55
2.755GlnVal: 2.755 ± 0.932
0.306GlnTrp: 0.306 ± 0.183
0.918GlnTyr: 0.918 ± 0.361
0.0GlnXaa: 0.0 ± 0.0
Arg
3.367ArgAla: 3.367 ± 1.194
0.918ArgCys: 0.918 ± 0.55
3.061ArgAsp: 3.061 ± 0.573
1.837ArgGlu: 1.837 ± 0.459
4.591ArgPhe: 4.591 ± 1.048
3.673ArgGly: 3.673 ± 0.36
1.837ArgHis: 1.837 ± 0.686
4.285ArgIle: 4.285 ± 1.029
1.53ArgLys: 1.53 ± 0.917
5.816ArgLeu: 5.816 ± 0.995
1.224ArgMet: 1.224 ± 0.336
2.143ArgAsn: 2.143 ± 1.138
2.449ArgPro: 2.449 ± 0.694
2.755ArgGln: 2.755 ± 0.408
3.061ArgArg: 3.061 ± 0.588
2.755ArgSer: 2.755 ± 0.408
2.449ArgThr: 2.449 ± 0.219
2.755ArgVal: 2.755 ± 0.056
0.918ArgTrp: 0.918 ± 0.186
2.755ArgTyr: 2.755 ± 0.842
0.0ArgXaa: 0.0 ± 0.0
Ser
5.204SerAla: 5.204 ± 0.262
0.612SerCys: 0.612 ± 0.153
4.285SerAsp: 4.285 ± 1.627
4.591SerGlu: 4.591 ± 1.542
3.061SerPhe: 3.061 ± 0.699
5.204SerGly: 5.204 ± 1.163
2.449SerHis: 2.449 ± 1.048
4.591SerIle: 4.591 ± 0.513
1.53SerLys: 1.53 ± 0.64
7.652SerLeu: 7.652 ± 2.59
2.143SerMet: 2.143 ± 0.705
2.755SerAsn: 2.755 ± 0.945
1.837SerPro: 1.837 ± 0.459
1.224SerGln: 1.224 ± 0.336
2.755SerArg: 2.755 ± 0.564
5.51SerSer: 5.51 ± 0.991
6.428SerThr: 6.428 ± 2.08
4.285SerVal: 4.285 ± 0.198
0.306SerTrp: 0.306 ± 0.183
2.755SerTyr: 2.755 ± 0.54
0.0SerXaa: 0.0 ± 0.0
Thr
4.897ThrAla: 4.897 ± 1.007
0.918ThrCys: 0.918 ± 0.186
2.755ThrAsp: 2.755 ± 0.564
4.897ThrGlu: 4.897 ± 0.048
2.449ThrPhe: 2.449 ± 0.971
2.143ThrGly: 2.143 ± 0.42
3.979ThrHis: 3.979 ± 0.448
5.204ThrIle: 5.204 ± 1.557
3.061ThrLys: 3.061 ± 1.293
11.019ThrLeu: 11.019 ± 1.533
1.837ThrMet: 1.837 ± 0.723
2.143ThrAsn: 2.143 ± 0.511
5.204ThrPro: 5.204 ± 0.951
2.449ThrGln: 2.449 ± 0.971
5.204ThrArg: 5.204 ± 1.026
6.734ThrSer: 6.734 ± 2.639
7.958ThrThr: 7.958 ± 0.721
4.591ThrVal: 4.591 ± 1.066
0.306ThrTrp: 0.306 ± 0.183
2.755ThrTyr: 2.755 ± 1.734
0.0ThrXaa: 0.0 ± 0.0
Val
4.897ValAla: 4.897 ± 0.048
0.612ValCys: 0.612 ± 0.367
2.449ValAsp: 2.449 ± 0.503
5.204ValGlu: 5.204 ± 0.666
2.755ValPhe: 2.755 ± 0.056
3.061ValGly: 3.061 ± 0.503
2.143ValHis: 2.143 ± 0.867
3.061ValIle: 3.061 ± 1.017
1.837ValLys: 1.837 ± 0.459
3.367ValLeu: 3.367 ± 0.919
1.837ValMet: 1.837 ± 0.18
3.367ValAsn: 3.367 ± 0.208
2.449ValPro: 2.449 ± 0.503
1.837ValGln: 1.837 ± 0.361
2.449ValArg: 2.449 ± 0.503
4.591ValSer: 4.591 ± 0.619
5.816ValThr: 5.816 ± 2.294
3.061ValVal: 3.061 ± 1.362
0.612ValTrp: 0.612 ± 0.153
3.061ValTyr: 3.061 ± 0.573
0.0ValXaa: 0.0 ± 0.0
Trp
0.612TrpAla: 0.612 ± 0.367
0.306TrpCys: 0.306 ± 0.183
0.0TrpAsp: 0.0 ± 0.0
0.306TrpGlu: 0.306 ± 0.183
0.612TrpPhe: 0.612 ± 0.153
0.0TrpGly: 0.0 ± 0.0
0.306TrpHis: 0.306 ± 0.183
0.0TrpIle: 0.0 ± 0.0
0.306TrpLys: 0.306 ± 0.183
1.224TrpLeu: 1.224 ± 0.336
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.306TrpPro: 0.306 ± 0.282
0.612TrpGln: 0.612 ± 0.153
0.306TrpArg: 0.306 ± 0.431
0.612TrpSer: 0.612 ± 0.153
0.918TrpThr: 0.918 ± 0.361
1.224TrpVal: 1.224 ± 0.336
0.0TrpTrp: 0.0 ± 0.0
0.612TrpTyr: 0.612 ± 0.153
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.224TyrAla: 1.224 ± 0.336
0.918TyrCys: 0.918 ± 0.55
2.143TyrAsp: 2.143 ± 0.867
2.449TyrGlu: 2.449 ± 0.672
0.306TyrPhe: 0.306 ± 0.282
2.449TyrGly: 2.449 ± 0.694
1.53TyrHis: 1.53 ± 0.917
3.673TyrIle: 3.673 ± 0.755
0.612TyrLys: 0.612 ± 0.564
1.224TyrLeu: 1.224 ± 0.693
0.0TyrMet: 0.0 ± 0.0
2.143TyrAsn: 2.143 ± 0.612
0.612TyrPro: 0.612 ± 0.153
1.53TyrGln: 1.53 ± 0.64
3.061TyrArg: 3.061 ± 0.776
1.837TyrSer: 1.837 ± 0.621
5.51TyrThr: 5.51 ± 1.316
2.755TyrVal: 2.755 ± 0.469
0.306TyrTrp: 0.306 ± 0.183
0.612TyrTyr: 0.612 ± 0.367
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3268 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski