Amino acid dipepetide frequency for Maize-associated totivirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.775AlaAla: 8.775 ± 0.195
2.507AlaCys: 2.507 ± 0.056
4.387AlaAsp: 4.387 ± 1.208
5.014AlaGlu: 5.014 ± 0.631
5.014AlaPhe: 5.014 ± 1.152
3.447AlaGly: 3.447 ± 0.883
1.88AlaHis: 1.88 ± 0.22
5.954AlaIle: 5.954 ± 0.667
6.268AlaLys: 6.268 ± 0.907
10.028AlaLeu: 10.028 ± 0.741
5.327AlaMet: 5.327 ± 0.319
1.567AlaAsn: 1.567 ± 0.517
1.254AlaPro: 1.254 ± 0.488
3.134AlaGln: 3.134 ± 0.714
5.641AlaArg: 5.641 ± 0.141
2.507AlaSer: 2.507 ± 0.467
5.641AlaThr: 5.641 ± 1.702
5.641AlaVal: 5.641 ± 1.181
2.507AlaTrp: 2.507 ± 0.576
2.507AlaTyr: 2.507 ± 0.988
0.0AlaXaa: 0.0 ± 0.0
Cys
1.254CysAla: 1.254 ± 0.028
0.0CysCys: 0.0 ± 0.0
1.88CysAsp: 1.88 ± 0.22
2.507CysGlu: 2.507 ± 0.467
0.627CysPhe: 0.627 ± 0.247
0.0CysGly: 0.0 ± 0.0
0.627CysHis: 0.627 ± 0.274
0.0CysIle: 0.0 ± 0.0
0.627CysLys: 0.627 ± 0.274
1.254CysLeu: 1.254 ± 0.449
0.0CysMet: 0.0 ± 0.0
0.94CysAsn: 0.94 ± 0.303
0.94CysPro: 0.94 ± 0.348
1.88CysGln: 1.88 ± 0.823
0.313CysArg: 0.313 ± 0.198
0.0CysSer: 0.0 ± 0.0
0.627CysThr: 0.627 ± 0.274
0.627CysVal: 0.627 ± 0.247
0.0CysTrp: 0.0 ± 0.0
0.627CysTyr: 0.627 ± 0.247
0.0CysXaa: 0.0 ± 0.0
Asp
4.074AspAla: 4.074 ± 0.406
0.627AspCys: 0.627 ± 0.274
5.014AspAsp: 5.014 ± 0.413
3.134AspGlu: 3.134 ± 0.85
3.761AspPhe: 3.761 ± 0.44
2.507AspGly: 2.507 ± 0.467
0.0AspHis: 0.0 ± 0.0
4.387AspIle: 4.387 ± 0.878
2.507AspLys: 2.507 ± 0.467
3.761AspLeu: 3.761 ± 0.44
1.254AspMet: 1.254 ± 0.494
1.88AspAsn: 1.88 ± 0.302
2.507AspPro: 2.507 ± 0.576
3.447AspGln: 3.447 ± 0.883
4.387AspArg: 4.387 ± 0.357
5.014AspSer: 5.014 ± 0.112
4.701AspThr: 4.701 ± 0.41
8.148AspVal: 8.148 ± 0.093
0.627AspTrp: 0.627 ± 0.247
0.627AspTyr: 0.627 ± 0.247
0.0AspXaa: 0.0 ± 0.0
Glu
4.074GluAla: 4.074 ± 0.462
0.627GluCys: 0.627 ± 0.274
3.761GluAsp: 3.761 ± 0.084
3.134GluGlu: 3.134 ± 0.193
3.761GluPhe: 3.761 ± 0.603
3.761GluGly: 3.761 ± 0.603
2.507GluHis: 2.507 ± 0.467
3.134GluIle: 3.134 ± 0.714
1.254GluLys: 1.254 ± 0.028
5.641GluLeu: 5.641 ± 0.141
0.627GluMet: 0.627 ± 0.274
0.627GluAsn: 0.627 ± 0.274
1.254GluPro: 1.254 ± 0.494
1.567GluGln: 1.567 ± 0.312
4.387GluArg: 4.387 ± 0.687
3.134GluSer: 3.134 ± 0.193
1.88GluThr: 1.88 ± 0.823
4.074GluVal: 4.074 ± 0.203
1.88GluTrp: 1.88 ± 0.22
3.761GluTyr: 3.761 ± 0.603
0.0GluXaa: 0.0 ± 0.0
Phe
2.507PheAla: 2.507 ± 0.056
1.88PheCys: 1.88 ± 0.302
5.641PheAsp: 5.641 ± 0.141
3.761PheGlu: 3.761 ± 0.084
1.88PhePhe: 1.88 ± 0.823
1.254PheGly: 1.254 ± 0.494
1.254PheHis: 1.254 ± 0.494
1.254PheIle: 1.254 ± 0.028
5.014PheLys: 5.014 ± 0.631
4.387PheLeu: 4.387 ± 0.167
1.88PheMet: 1.88 ± 0.302
1.88PheAsn: 1.88 ± 0.302
1.254PhePro: 1.254 ± 0.028
1.88PheGln: 1.88 ± 0.302
1.567PheArg: 1.567 ± 0.835
2.82PheSer: 2.82 ± 0.198
0.627PheThr: 0.627 ± 0.274
4.387PheVal: 4.387 ± 0.357
0.627PheTrp: 0.627 ± 0.274
1.254PheTyr: 1.254 ± 0.028
0.0PheXaa: 0.0 ± 0.0
Gly
6.268GlyAla: 6.268 ± 0.658
0.94GlyCys: 0.94 ± 0.303
2.507GlyAsp: 2.507 ± 0.056
3.761GlyGlu: 3.761 ± 0.784
3.134GlyPhe: 3.134 ± 0.329
3.761GlyGly: 3.761 ± 0.44
0.0GlyHis: 0.0 ± 0.0
2.507GlyIle: 2.507 ± 0.467
3.761GlyLys: 3.761 ± 0.603
5.641GlyLeu: 5.641 ± 1.426
1.88GlyMet: 1.88 ± 0.302
0.627GlyAsn: 0.627 ± 0.247
1.567GlyPro: 1.567 ± 0.354
1.254GlyGln: 1.254 ± 0.028
3.134GlyArg: 3.134 ± 0.329
1.567GlySer: 1.567 ± 0.196
3.761GlyThr: 3.761 ± 0.957
5.954GlyVal: 5.954 ± 0.258
0.627GlyTrp: 0.627 ± 0.247
1.254GlyTyr: 1.254 ± 0.494
0.0GlyXaa: 0.0 ± 0.0
His
2.507HisAla: 2.507 ± 0.467
0.0HisCys: 0.0 ± 0.0
2.507HisAsp: 2.507 ± 0.056
1.254HisGlu: 1.254 ± 0.494
0.627HisPhe: 0.627 ± 0.274
1.254HisGly: 1.254 ± 0.494
1.254HisHis: 1.254 ± 0.494
1.254HisIle: 1.254 ± 0.028
1.88HisLys: 1.88 ± 0.22
2.507HisLeu: 2.507 ± 0.467
0.0HisMet: 0.0 ± 0.0
1.88HisAsn: 1.88 ± 0.22
0.0HisPro: 0.0 ± 0.0
0.627HisGln: 0.627 ± 0.247
3.134HisArg: 3.134 ± 1.235
1.88HisSer: 1.88 ± 0.741
1.88HisThr: 1.88 ± 0.302
2.507HisVal: 2.507 ± 0.056
0.0HisTrp: 0.0 ± 0.0
1.254HisTyr: 1.254 ± 0.494
0.0HisXaa: 0.0 ± 0.0
Ile
6.268IleAla: 6.268 ± 0.907
0.627IleCys: 0.627 ± 0.247
4.387IleAsp: 4.387 ± 0.357
2.194IleGlu: 2.194 ± 1.103
2.507IlePhe: 2.507 ± 0.056
2.507IleGly: 2.507 ± 0.056
3.134IleHis: 3.134 ± 0.714
1.254IleIle: 1.254 ± 0.494
1.88IleLys: 1.88 ± 0.22
2.507IleLeu: 2.507 ± 0.056
1.254IleMet: 1.254 ± 0.494
3.761IleAsn: 3.761 ± 0.603
3.447IlePro: 3.447 ± 0.502
1.254IleGln: 1.254 ± 0.028
3.761IleArg: 3.761 ± 0.44
3.761IleSer: 3.761 ± 0.44
2.82IleThr: 2.82 ± 0.198
3.134IleVal: 3.134 ± 1.235
1.88IleTrp: 1.88 ± 0.22
1.88IleTyr: 1.88 ± 0.302
0.0IleXaa: 0.0 ± 0.0
Lys
4.387LysAla: 4.387 ± 1.729
0.627LysCys: 0.627 ± 0.247
1.254LysAsp: 1.254 ± 0.494
3.134LysGlu: 3.134 ± 0.193
2.507LysPhe: 2.507 ± 0.576
1.254LysGly: 1.254 ± 0.028
1.88LysHis: 1.88 ± 0.741
5.641LysIle: 5.641 ± 0.141
1.254LysLys: 1.254 ± 0.549
0.627LysLeu: 0.627 ± 0.274
1.88LysMet: 1.88 ± 0.22
1.88LysAsn: 1.88 ± 0.22
1.254LysPro: 1.254 ± 0.494
4.387LysGln: 4.387 ± 0.357
1.88LysArg: 1.88 ± 0.741
1.88LysSer: 1.88 ± 0.302
3.134LysThr: 3.134 ± 0.193
2.507LysVal: 2.507 ± 0.056
0.627LysTrp: 0.627 ± 0.274
3.761LysTyr: 3.761 ± 0.44
0.0LysXaa: 0.0 ± 0.0
Leu
5.954LeuAla: 5.954 ± 0.258
0.0LeuCys: 0.0 ± 0.0
5.014LeuAsp: 5.014 ± 0.631
3.761LeuGlu: 3.761 ± 0.603
1.88LeuPhe: 1.88 ± 0.302
3.447LeuGly: 3.447 ± 0.255
1.254LeuHis: 1.254 ± 0.028
0.627LeuIle: 0.627 ± 0.247
4.387LeuLys: 4.387 ± 0.167
6.894LeuLeu: 6.894 ± 0.116
2.194LeuMet: 2.194 ± 0.19
4.387LeuAsn: 4.387 ± 0.687
6.894LeuPro: 6.894 ± 1.453
1.88LeuGln: 1.88 ± 0.302
6.894LeuArg: 6.894 ± 0.412
5.327LeuSer: 5.327 ± 0.667
8.775LeuThr: 8.775 ± 0.333
5.014LeuVal: 5.014 ± 1.455
0.0LeuTrp: 0.0 ± 0.0
4.387LeuTyr: 4.387 ± 0.357
0.0LeuXaa: 0.0 ± 0.0
Met
1.88MetAla: 1.88 ± 0.22
0.0MetCys: 0.0 ± 0.0
2.507MetAsp: 2.507 ± 0.576
0.0MetGlu: 0.0 ± 0.0
1.254MetPhe: 1.254 ± 0.494
1.88MetGly: 1.88 ± 0.302
1.254MetHis: 1.254 ± 0.028
0.627MetIle: 0.627 ± 0.274
0.627MetLys: 0.627 ± 0.274
3.134MetLeu: 3.134 ± 0.329
1.254MetMet: 1.254 ± 0.028
1.88MetAsn: 1.88 ± 0.302
1.88MetPro: 1.88 ± 0.302
0.627MetGln: 0.627 ± 0.247
1.254MetArg: 1.254 ± 0.549
3.761MetSer: 3.761 ± 0.084
1.254MetThr: 1.254 ± 0.028
0.627MetVal: 0.627 ± 0.247
0.627MetTrp: 0.627 ± 0.247
1.254MetTyr: 1.254 ± 0.494
0.0MetXaa: 0.0 ± 0.0
Asn
3.134AsnAla: 3.134 ± 0.193
0.0AsnCys: 0.0 ± 0.0
1.254AsnAsp: 1.254 ± 0.549
2.507AsnGlu: 2.507 ± 0.056
2.507AsnPhe: 2.507 ± 0.576
1.254AsnGly: 1.254 ± 0.028
1.254AsnHis: 1.254 ± 0.028
4.387AsnIle: 4.387 ± 1.208
0.0AsnLys: 0.0 ± 0.0
1.88AsnLeu: 1.88 ± 0.302
2.507AsnMet: 2.507 ± 0.576
1.88AsnAsn: 1.88 ± 0.302
0.627AsnPro: 0.627 ± 0.274
0.627AsnGln: 0.627 ± 0.274
3.134AsnArg: 3.134 ± 0.715
0.627AsnSer: 0.627 ± 0.247
1.88AsnThr: 1.88 ± 0.302
2.507AsnVal: 2.507 ± 0.988
0.627AsnTrp: 0.627 ± 0.274
2.507AsnTyr: 2.507 ± 0.056
0.0AsnXaa: 0.0 ± 0.0
Pro
4.387ProAla: 4.387 ± 0.357
0.627ProCys: 0.627 ± 0.247
3.447ProAsp: 3.447 ± 1.131
5.641ProGlu: 5.641 ± 0.141
1.88ProPhe: 1.88 ± 0.823
5.014ProGly: 5.014 ± 0.112
1.254ProHis: 1.254 ± 0.494
4.074ProIle: 4.074 ± 0.734
0.0ProLys: 0.0 ± 0.0
3.134ProLeu: 3.134 ± 0.329
1.254ProMet: 1.254 ± 0.549
0.627ProAsn: 0.627 ± 0.274
4.074ProPro: 4.074 ± 0.283
0.627ProGln: 0.627 ± 0.247
1.254ProArg: 1.254 ± 0.549
0.0ProSer: 0.0 ± 0.0
4.387ProThr: 4.387 ± 0.878
3.447ProVal: 3.447 ± 0.627
0.0ProTrp: 0.0 ± 0.0
1.88ProTyr: 1.88 ± 0.22
0.0ProXaa: 0.0 ± 0.0
Gln
5.954GlnAla: 5.954 ± 0.46
2.194GlnCys: 2.194 ± 0.367
2.507GlnAsp: 2.507 ± 0.576
3.134GlnGlu: 3.134 ± 0.329
1.254GlnPhe: 1.254 ± 0.549
1.254GlnGly: 1.254 ± 0.028
2.507GlnHis: 2.507 ± 0.988
1.88GlnIle: 1.88 ± 0.22
1.254GlnLys: 1.254 ± 0.494
0.627GlnLeu: 0.627 ± 0.274
0.0GlnMet: 0.0 ± 0.0
1.88GlnAsn: 1.88 ± 0.823
1.88GlnPro: 1.88 ± 0.22
1.254GlnGln: 1.254 ± 0.028
1.88GlnArg: 1.88 ± 0.22
1.88GlnSer: 1.88 ± 0.823
1.254GlnThr: 1.254 ± 0.549
1.254GlnVal: 1.254 ± 0.028
0.0GlnTrp: 0.0 ± 0.0
3.134GlnTyr: 3.134 ± 0.193
0.0GlnXaa: 0.0 ± 0.0
Arg
5.954ArgAla: 5.954 ± 1.179
2.194ArgCys: 2.194 ± 0.751
4.701ArgAsp: 4.701 ± 0.909
0.627ArgGlu: 0.627 ± 0.247
4.387ArgPhe: 4.387 ± 0.357
7.208ArgGly: 7.208 ± 2.515
1.254ArgHis: 1.254 ± 0.028
3.134ArgIle: 3.134 ± 0.85
4.387ArgLys: 4.387 ± 1.729
3.447ArgLeu: 3.447 ± 0.627
1.254ArgMet: 1.254 ± 0.028
2.507ArgAsn: 2.507 ± 0.467
2.507ArgPro: 2.507 ± 0.467
2.507ArgGln: 2.507 ± 0.467
6.268ArgArg: 6.268 ± 0.139
5.327ArgSer: 5.327 ± 0.936
3.134ArgThr: 3.134 ± 0.193
6.894ArgVal: 6.894 ± 0.412
0.627ArgTrp: 0.627 ± 0.247
1.88ArgTyr: 1.88 ± 0.302
0.0ArgXaa: 0.0 ± 0.0
Ser
5.641SerAla: 5.641 ± 0.141
0.627SerCys: 0.627 ± 0.396
2.507SerAsp: 2.507 ± 0.988
0.0SerGlu: 0.0 ± 0.0
1.254SerPhe: 1.254 ± 0.494
1.88SerGly: 1.88 ± 0.302
0.627SerHis: 0.627 ± 0.247
3.134SerIle: 3.134 ± 0.329
1.88SerLys: 1.88 ± 0.22
3.134SerLeu: 3.134 ± 0.329
3.134SerMet: 3.134 ± 0.193
3.134SerAsn: 3.134 ± 0.85
1.254SerPro: 1.254 ± 0.494
3.134SerGln: 3.134 ± 0.714
3.134SerArg: 3.134 ± 0.714
3.447SerSer: 3.447 ± 1.397
5.641SerThr: 5.641 ± 0.384
4.387SerVal: 4.387 ± 1.208
2.507SerTrp: 2.507 ± 0.507
2.507SerTyr: 2.507 ± 1.097
0.0SerXaa: 0.0 ± 0.0
Thr
4.074ThrAla: 4.074 ± 0.203
1.254ThrCys: 1.254 ± 0.549
1.88ThrAsp: 1.88 ± 0.823
5.641ThrGlu: 5.641 ± 0.141
3.761ThrPhe: 3.761 ± 0.084
4.074ThrGly: 4.074 ± 0.203
1.254ThrHis: 1.254 ± 0.028
1.254ThrIle: 1.254 ± 0.028
3.134ThrLys: 3.134 ± 0.193
6.894ThrLeu: 6.894 ± 0.116
0.313ThrMet: 0.313 ± 0.198
1.254ThrAsn: 1.254 ± 0.028
5.014ThrPro: 5.014 ± 0.631
2.507ThrGln: 2.507 ± 0.056
6.581ThrArg: 6.581 ± 0.692
3.761ThrSer: 3.761 ± 0.44
5.641ThrThr: 5.641 ± 0.141
6.268ThrVal: 6.268 ± 0.658
1.88ThrTrp: 1.88 ± 0.302
2.507ThrTyr: 2.507 ± 1.097
0.0ThrXaa: 0.0 ± 0.0
Val
7.521ValAla: 7.521 ± 0.167
0.0ValCys: 0.0 ± 0.0
5.014ValAsp: 5.014 ± 0.934
2.507ValGlu: 2.507 ± 0.467
3.134ValPhe: 3.134 ± 1.235
5.641ValGly: 5.641 ± 1.181
2.507ValHis: 2.507 ± 0.467
5.954ValIle: 5.954 ± 0.46
3.761ValLys: 3.761 ± 1.482
7.521ValLeu: 7.521 ± 0.36
1.254ValMet: 1.254 ± 0.549
1.88ValAsn: 1.88 ± 0.22
5.014ValPro: 5.014 ± 1.152
1.254ValGln: 1.254 ± 0.028
4.387ValArg: 4.387 ± 0.357
4.387ValSer: 4.387 ± 0.167
9.401ValThr: 9.401 ± 0.987
4.387ValVal: 4.387 ± 0.167
0.627ValTrp: 0.627 ± 0.247
0.627ValTyr: 0.627 ± 0.247
0.0ValXaa: 0.0 ± 0.0
Trp
1.254TrpAla: 1.254 ± 0.494
0.0TrpCys: 0.0 ± 0.0
0.313TrpAsp: 0.313 ± 0.198
1.254TrpGlu: 1.254 ± 0.028
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.254TrpHis: 1.254 ± 0.549
0.0TrpIle: 0.0 ± 0.0
0.627TrpLys: 0.627 ± 0.274
1.88TrpLeu: 1.88 ± 0.22
0.0TrpMet: 0.0 ± 0.0
0.627TrpAsn: 0.627 ± 0.274
1.88TrpPro: 1.88 ± 0.823
0.627TrpGln: 0.627 ± 0.274
3.447TrpArg: 3.447 ± 0.255
0.627TrpSer: 0.627 ± 0.247
1.88TrpThr: 1.88 ± 0.302
1.254TrpVal: 1.254 ± 0.494
0.313TrpTrp: 0.313 ± 0.198
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.134TyrAla: 3.134 ± 0.193
0.0TyrCys: 0.0 ± 0.0
1.88TyrAsp: 1.88 ± 0.302
1.88TyrGlu: 1.88 ± 0.741
1.88TyrPhe: 1.88 ± 0.22
2.507TyrGly: 2.507 ± 0.576
1.254TyrHis: 1.254 ± 0.494
3.761TyrIle: 3.761 ± 0.44
1.254TyrLys: 1.254 ± 0.028
4.387TyrLeu: 4.387 ± 0.687
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.507TyrPro: 2.507 ± 0.056
2.507TyrGln: 2.507 ± 1.097
3.761TyrArg: 3.761 ± 0.961
1.254TyrSer: 1.254 ± 0.028
0.627TyrThr: 0.627 ± 0.274
3.761TyrVal: 3.761 ± 0.603
1.254TyrTrp: 1.254 ± 0.549
0.627TyrTyr: 0.627 ± 0.247
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3192 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski