Amino acid dipepetide frequency for Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 / KCTC 4070 / PR3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.256AlaAla: 12.256 ± 0.144	0.695AlaCys: 0.695 ± 0.025	8.824AlaAsp: 8.824 ± 0.124	8.23AlaGlu: 8.23 ± 0.104	4.02AlaPhe: 4.02 ± 0.078	8.273AlaGly: 8.273 ± 0.107	1.85AlaHis: 1.85 ± 0.045	4.475AlaIle: 4.475 ± 0.063	2.171AlaLys: 2.171 ± 0.049	9.197AlaLeu: 9.197 ± 0.109	1.968AlaMet: 1.968 ± 0.043	2.548AlaAsn: 2.548 ± 0.049	3.648AlaPro: 3.648 ± 0.063	2.315AlaGln: 2.315 ± 0.055	5.576AlaArg: 5.576 ± 0.079	5.597AlaSer: 5.597 ± 0.088	6.698AlaThr: 6.698 ± 0.088	9.968AlaVal: 9.968 ± 0.122	1.135AlaTrp: 1.135 ± 0.033	2.599AlaTyr: 2.599 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.617CysAla: 0.617 ± 0.025	0.084CysCys: 0.084 ± 0.009	0.601CysAsp: 0.601 ± 0.025	0.583CysGlu: 0.583 ± 0.025	0.204CysPhe: 0.204 ± 0.013	0.794CysGly: 0.794 ± 0.027	0.173CysHis: 0.173 ± 0.013	0.285CysIle: 0.285 ± 0.017	0.135CysLys: 0.135 ± 0.011	0.546CysLeu: 0.546 ± 0.021	0.104CysMet: 0.104 ± 0.01	0.197CysAsn: 0.197 ± 0.015	0.505CysPro: 0.505 ± 0.024	0.149CysGln: 0.149 ± 0.011	0.433CysArg: 0.433 ± 0.022	0.45CysSer: 0.45 ± 0.017	0.388CysThr: 0.388 ± 0.018	0.493CysVal: 0.493 ± 0.022	0.086CysTrp: 0.086 ± 0.008	0.176CysTyr: 0.176 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	9.507AspAla: 9.507 ± 0.135	0.615AspCys: 0.615 ± 0.021	7.771AspAsp: 7.771 ± 0.13	8.018AspGlu: 8.018 ± 0.114	2.165AspPhe: 2.165 ± 0.051	7.528AspGly: 7.528 ± 0.115	1.679AspHis: 1.679 ± 0.046	3.62AspIle: 3.62 ± 0.074	1.369AspLys: 1.369 ± 0.039	6.147AspLeu: 6.147 ± 0.094	1.32AspMet: 1.32 ± 0.032	1.56AspAsn: 1.56 ± 0.038	4.097AspPro: 4.097 ± 0.064	1.679AspGln: 1.679 ± 0.048	5.398AspArg: 5.398 ± 0.078	4.36AspSer: 4.36 ± 0.068	4.461AspThr: 4.461 ± 0.082	7.416AspVal: 7.416 ± 0.09	0.957AspTrp: 0.957 ± 0.03	1.885AspTyr: 1.885 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	7.866GluAla: 7.866 ± 0.103	0.482GluCys: 0.482 ± 0.024	5.596GluAsp: 5.596 ± 0.093	6.506GluGlu: 6.506 ± 0.115	3.019GluPhe: 3.019 ± 0.06	4.797GluGly: 4.797 ± 0.069	1.911GluHis: 1.911 ± 0.045	3.783GluIle: 3.783 ± 0.067	2.295GluLys: 2.295 ± 0.054	7.564GluLeu: 7.564 ± 0.103	2.04GluMet: 2.04 ± 0.044	2.657GluAsn: 2.657 ± 0.051	3.281GluPro: 3.281 ± 0.058	2.938GluGln: 2.938 ± 0.067	6.728GluArg: 6.728 ± 0.104	5.773GluSer: 5.773 ± 0.085	6.909GluThr: 6.909 ± 0.098	5.498GluVal: 5.498 ± 0.083	1.117GluTrp: 1.117 ± 0.033	2.655GluTyr: 2.655 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	3.548PheAla: 3.548 ± 0.06	0.281PheCys: 0.281 ± 0.016	3.432PheAsp: 3.432 ± 0.067	3.343PheGlu: 3.343 ± 0.065	1.15PhePhe: 1.15 ± 0.035	3.365PheGly: 3.365 ± 0.063	0.652PheHis: 0.652 ± 0.026	1.253PheIle: 1.253 ± 0.04	0.568PheLys: 0.568 ± 0.021	2.982PheLeu: 2.982 ± 0.067	0.534PheMet: 0.534 ± 0.024	0.794PheAsn: 0.794 ± 0.026	1.411PhePro: 1.411 ± 0.032	0.82PheGln: 0.82 ± 0.026	1.817PheArg: 1.817 ± 0.035	2.027PheSer: 2.027 ± 0.044	2.036PheThr: 2.036 ± 0.047	3.397PheVal: 3.397 ± 0.068	0.426PheTrp: 0.426 ± 0.021	0.917PheTyr: 0.917 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	7.201GlyAla: 7.201 ± 0.1	0.68GlyCys: 0.68 ± 0.028	6.45GlyAsp: 6.45 ± 0.102	6.374GlyGlu: 6.374 ± 0.079	3.086GlyPhe: 3.086 ± 0.063	6.947GlyGly: 6.947 ± 0.111	1.618GlyHis: 1.618 ± 0.047	4.348GlyIle: 4.348 ± 0.073	2.12GlyLys: 2.12 ± 0.048	6.886GlyLeu: 6.886 ± 0.104	1.629GlyMet: 1.629 ± 0.037	2.207GlyAsn: 2.207 ± 0.053	3.039GlyPro: 3.039 ± 0.051	2.115GlyGln: 2.115 ± 0.049	4.585GlyArg: 4.585 ± 0.072	5.181GlySer: 5.181 ± 0.081	5.86GlyThr: 5.86 ± 0.083	7.367GlyVal: 7.367 ± 0.104	1.034GlyTrp: 1.034 ± 0.034	2.699GlyTyr: 2.699 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.933HisAla: 1.933 ± 0.047	0.188HisCys: 0.188 ± 0.013	1.798HisAsp: 1.798 ± 0.051	1.775HisGlu: 1.775 ± 0.04	0.565HisPhe: 0.565 ± 0.026	1.94HisGly: 1.94 ± 0.05	0.519HisHis: 0.519 ± 0.024	0.786HisIle: 0.786 ± 0.026	0.367HisLys: 0.367 ± 0.017	1.796HisLeu: 1.796 ± 0.04	0.265HisMet: 0.265 ± 0.018	0.505HisAsn: 0.505 ± 0.022	1.211HisPro: 1.211 ± 0.032	0.496HisGln: 0.496 ± 0.022	1.318HisArg: 1.318 ± 0.041	0.918HisSer: 0.918 ± 0.036	1.142HisThr: 1.142 ± 0.035	1.919HisVal: 1.919 ± 0.042	0.227HisTrp: 0.227 ± 0.014	0.589HisTyr: 0.589 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	4.587IleAla: 4.587 ± 0.078	0.277IleCys: 0.277 ± 0.015	3.865IleAsp: 3.865 ± 0.058	4.236IleGlu: 4.236 ± 0.073	1.103IlePhe: 1.103 ± 0.038	3.739IleGly: 3.739 ± 0.066	0.934IleHis: 0.934 ± 0.032	1.606IleIle: 1.606 ± 0.045	0.815IleLys: 0.815 ± 0.033	3.503IleLeu: 3.503 ± 0.073	0.489IleMet: 0.489 ± 0.022	1.047IleAsn: 1.047 ± 0.028	2.298IlePro: 2.298 ± 0.051	1.188IleGln: 1.188 ± 0.035	2.83IleArg: 2.83 ± 0.053	2.599IleSer: 2.599 ± 0.053	2.498IleThr: 2.498 ± 0.053	3.822IleVal: 3.822 ± 0.078	0.348IleTrp: 0.348 ± 0.017	0.887IleTyr: 0.887 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.039LysAla: 2.039 ± 0.044	0.127LysCys: 0.127 ± 0.01	1.301LysAsp: 1.301 ± 0.037	1.663LysGlu: 1.663 ± 0.045	0.655LysPhe: 0.655 ± 0.025	1.503LysGly: 1.503 ± 0.039	0.63LysHis: 0.63 ± 0.022	0.972LysIle: 0.972 ± 0.032	0.707LysLys: 0.707 ± 0.032	1.936LysLeu: 1.936 ± 0.046	0.473LysMet: 0.473 ± 0.021	0.766LysAsn: 0.766 ± 0.03	1.12LysPro: 1.12 ± 0.039	1.011LysGln: 1.011 ± 0.031	1.965LysArg: 1.965 ± 0.05	1.534LysSer: 1.534 ± 0.038	1.708LysThr: 1.708 ± 0.039	1.393LysVal: 1.393 ± 0.04	0.292LysTrp: 0.292 ± 0.016	0.752LysTyr: 0.752 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	9.702LeuAla: 9.702 ± 0.126	0.591LeuCys: 0.591 ± 0.025	7.287LeuAsp: 7.287 ± 0.101	5.986LeuGlu: 5.986 ± 0.085	3.312LeuPhe: 3.312 ± 0.069	7.287LeuGly: 7.287 ± 0.101	1.557LeuHis: 1.557 ± 0.042	3.189LeuIle: 3.189 ± 0.053	1.865LeuLys: 1.865 ± 0.045	8.019LeuLeu: 8.019 ± 0.116	1.349LeuMet: 1.349 ± 0.041	2.105LeuAsn: 2.105 ± 0.043	4.035LeuPro: 4.035 ± 0.075	2.15LeuGln: 2.15 ± 0.048	5.438LeuArg: 5.438 ± 0.079	6.518LeuSer: 6.518 ± 0.093	5.734LeuThr: 5.734 ± 0.089	8.08LeuVal: 8.08 ± 0.113	0.83LeuTrp: 0.83 ± 0.031	2.149LeuTyr: 2.149 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	1.763MetAla: 1.763 ± 0.038	0.12MetCys: 0.12 ± 0.01	1.304MetAsp: 1.304 ± 0.032	1.129MetGlu: 1.129 ± 0.036	0.594MetPhe: 0.594 ± 0.023	1.403MetGly: 1.403 ± 0.041	0.368MetHis: 0.368 ± 0.019	0.65MetIle: 0.65 ± 0.024	0.551MetLys: 0.551 ± 0.021	1.592MetLeu: 1.592 ± 0.044	0.34MetMet: 0.34 ± 0.016	0.678MetAsn: 0.678 ± 0.022	0.852MetPro: 0.852 ± 0.028	0.558MetGln: 0.558 ± 0.021	1.186MetArg: 1.186 ± 0.03	1.548MetSer: 1.548 ± 0.034	1.577MetThr: 1.577 ± 0.038	1.273MetVal: 1.273 ± 0.034	0.172MetTrp: 0.172 ± 0.014	0.46MetTyr: 0.46 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.919AsnAla: 2.919 ± 0.06	0.248AsnCys: 0.248 ± 0.015	1.994AsnAsp: 1.994 ± 0.04	2.108AsnGlu: 2.108 ± 0.053	0.75AsnPhe: 0.75 ± 0.028	2.364AsnGly: 2.364 ± 0.057	0.556AsnHis: 0.556 ± 0.022	1.186AsnIle: 1.186 ± 0.035	0.593AsnLys: 0.593 ± 0.028	2.247AsnLeu: 2.247 ± 0.049	0.47AsnMet: 0.47 ± 0.019	0.777AsnAsn: 0.777 ± 0.034	1.662AsnPro: 1.662 ± 0.037	0.737AsnGln: 0.737 ± 0.027	1.796AsnArg: 1.796 ± 0.044	1.388AsnSer: 1.388 ± 0.037	1.634AsnThr: 1.634 ± 0.042	2.606AsnVal: 2.606 ± 0.048	0.319AsnTrp: 0.319 ± 0.016	0.786AsnTyr: 0.786 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	4.039ProAla: 4.039 ± 0.061	0.235ProCys: 0.235 ± 0.015	4.605ProAsp: 4.605 ± 0.071	4.29ProGlu: 4.29 ± 0.06	1.669ProPhe: 1.669 ± 0.043	3.399ProGly: 3.399 ± 0.065	0.931ProHis: 0.931 ± 0.032	1.811ProIle: 1.811 ± 0.042	1.058ProLys: 1.058 ± 0.033	3.503ProLeu: 3.503 ± 0.059	0.809ProMet: 0.809 ± 0.029	1.365ProAsn: 1.365 ± 0.036	2.127ProPro: 2.127 ± 0.049	1.112ProGln: 1.112 ± 0.031	2.115ProArg: 2.115 ± 0.045	2.91ProSer: 2.91 ± 0.059	3.25ProThr: 3.25 ± 0.064	4.008ProVal: 4.008 ± 0.06	0.504ProTrp: 0.504 ± 0.022	1.165ProTyr: 1.165 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	2.363GlnAla: 2.363 ± 0.046	0.157GlnCys: 0.157 ± 0.012	1.337GlnAsp: 1.337 ± 0.037	1.737GlnGlu: 1.737 ± 0.044	1.188GlnPhe: 1.188 ± 0.032	1.599GlnGly: 1.599 ± 0.041	0.582GlnHis: 0.582 ± 0.023	1.21GlnIle: 1.21 ± 0.036	0.733GlnLys: 0.733 ± 0.027	2.375GlnLeu: 2.375 ± 0.054	0.665GlnMet: 0.665 ± 0.026	0.93GlnAsn: 0.93 ± 0.033	1.074GlnPro: 1.074 ± 0.04	1.188GlnGln: 1.188 ± 0.031	2.065GlnArg: 2.065 ± 0.05	2.165GlnSer: 2.165 ± 0.052	2.204GlnThr: 2.204 ± 0.048	1.842GlnVal: 1.842 ± 0.044	0.383GlnTrp: 0.383 ± 0.019	0.967GlnTyr: 0.967 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	5.805ArgAla: 5.805 ± 0.078	0.419ArgCys: 0.419 ± 0.02	5.0ArgAsp: 5.0 ± 0.087	6.067ArgGlu: 6.067 ± 0.078	2.317ArgPhe: 2.317 ± 0.046	4.276ArgGly: 4.276 ± 0.071	1.219ArgHis: 1.219 ± 0.036	3.035ArgIle: 3.035 ± 0.054	1.592ArgLys: 1.592 ± 0.043	5.931ArgLeu: 5.931 ± 0.086	1.294ArgMet: 1.294 ± 0.034	1.8ArgAsn: 1.8 ± 0.04	2.487ArgPro: 2.487 ± 0.05	1.875ArgGln: 1.875 ± 0.046	4.802ArgArg: 4.802 ± 0.08	3.557ArgSer: 3.557 ± 0.074	4.016ArgThr: 4.016 ± 0.071	5.177ArgVal: 5.177 ± 0.071	0.732ArgTrp: 0.732 ± 0.03	1.846ArgTyr: 1.846 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	5.728SerAla: 5.728 ± 0.096	0.365SerCys: 0.365 ± 0.019	5.205SerAsp: 5.205 ± 0.089	4.861SerGlu: 4.861 ± 0.085	2.172SerPhe: 2.172 ± 0.045	5.817SerGly: 5.817 ± 0.095	1.162SerHis: 1.162 ± 0.042	2.648SerIle: 2.648 ± 0.051	1.559SerLys: 1.559 ± 0.04	5.627SerLeu: 5.627 ± 0.068	1.182SerMet: 1.182 ± 0.036	1.908SerAsn: 1.908 ± 0.049	2.812SerPro: 2.812 ± 0.056	1.637SerGln: 1.637 ± 0.047	3.513SerArg: 3.513 ± 0.066	3.862SerSer: 3.862 ± 0.096	3.734SerThr: 3.734 ± 0.08	5.703SerVal: 5.703 ± 0.079	0.689SerTrp: 0.689 ± 0.027	1.488SerTyr: 1.488 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	7.035ThrAla: 7.035 ± 0.097	0.388ThrCys: 0.388 ± 0.02	5.748ThrAsp: 5.748 ± 0.086	5.174ThrGlu: 5.174 ± 0.078	2.325ThrPhe: 2.325 ± 0.057	5.739ThrGly: 5.739 ± 0.074	1.326ThrHis: 1.326 ± 0.04	2.924ThrIle: 2.924 ± 0.059	1.377ThrLys: 1.377 ± 0.037	5.988ThrLeu: 5.988 ± 0.075	1.124ThrMet: 1.124 ± 0.033	1.819ThrAsn: 1.819 ± 0.046	3.423ThrPro: 3.423 ± 0.064	1.583ThrGln: 1.583 ± 0.047	3.469ThrArg: 3.469 ± 0.062	3.406ThrSer: 3.406 ± 0.065	4.857ThrThr: 4.857 ± 0.08	7.242ThrVal: 7.242 ± 0.11	0.676ThrTrp: 0.676 ± 0.025	1.84ThrTyr: 1.84 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	9.628ValAla: 9.628 ± 0.123	0.7ValCys: 0.7 ± 0.023	5.987ValAsp: 5.987 ± 0.085	7.995ValGlu: 7.995 ± 0.111	3.119ValPhe: 3.119 ± 0.067	7.547ValGly: 7.547 ± 0.106	1.679ValHis: 1.679 ± 0.037	3.483ValIle: 3.483 ± 0.067	1.773ValLys: 1.773 ± 0.045	7.749ValLeu: 7.749 ± 0.1	1.434ValMet: 1.434 ± 0.038	2.342ValAsn: 2.342 ± 0.046	4.111ValPro: 4.111 ± 0.062	2.052ValGln: 2.052 ± 0.04	5.5ValArg: 5.5 ± 0.076	5.88ValSer: 5.88 ± 0.081	6.408ValThr: 6.408 ± 0.099	8.921ValVal: 8.921 ± 0.113	0.806ValTrp: 0.806 ± 0.032	2.174ValTyr: 2.174 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.865TrpAla: 0.865 ± 0.03	0.114TrpCys: 0.114 ± 0.01	0.839TrpAsp: 0.839 ± 0.027	0.842TrpGlu: 0.842 ± 0.034	0.484TrpPhe: 0.484 ± 0.021	0.799TrpGly: 0.799 ± 0.026	0.25TrpHis: 0.25 ± 0.016	0.465TrpIle: 0.465 ± 0.021	0.358TrpLys: 0.358 ± 0.018	1.044TrpLeu: 1.044 ± 0.039	0.234TrpMet: 0.234 ± 0.014	0.417TrpAsn: 0.417 ± 0.022	0.44TrpPro: 0.44 ± 0.019	0.396TrpGln: 0.396 ± 0.016	0.793TrpArg: 0.793 ± 0.03	0.662TrpSer: 0.662 ± 0.025	0.804TrpThr: 0.804 ± 0.029	0.906TrpVal: 0.906 ± 0.025	0.199TrpTrp: 0.199 ± 0.014	0.378TrpTyr: 0.378 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.643TyrAla: 2.643 ± 0.052	0.235TyrCys: 0.235 ± 0.015	2.609TyrAsp: 2.609 ± 0.055	2.496TyrGlu: 2.496 ± 0.043	0.858TyrPhe: 0.858 ± 0.027	2.311TyrGly: 2.311 ± 0.052	0.663TyrHis: 0.663 ± 0.024	0.942TyrIle: 0.942 ± 0.031	0.541TyrLys: 0.541 ± 0.025	2.548TyrLeu: 2.548 ± 0.051	0.396TyrMet: 0.396 ± 0.02	0.718TyrAsn: 0.718 ± 0.025	1.269TyrPro: 1.269 ± 0.033	0.764TyrGln: 0.764 ± 0.03	1.919TyrArg: 1.919 ± 0.046	1.338TyrSer: 1.338 ± 0.038	1.547TyrThr: 1.547 ± 0.037	2.258TyrVal: 2.258 ± 0.045	0.358TyrTrp: 0.358 ± 0.02	0.848TyrTyr: 0.848 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3894 proteins (1130016 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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