Amino acid dipepetide frequency for Bat polyomavirus 6b

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.575AlaAla: 8.575 ± 1.722
0.66AlaCys: 0.66 ± 0.812
2.639AlaAsp: 2.639 ± 0.921
3.958AlaGlu: 3.958 ± 2.495
2.639AlaPhe: 2.639 ± 0.847
5.277AlaGly: 5.277 ± 2.163
0.0AlaHis: 0.0 ± 0.0
5.277AlaIle: 5.277 ± 2.034
4.617AlaLys: 4.617 ± 1.911
6.596AlaLeu: 6.596 ± 3.22
0.66AlaMet: 0.66 ± 0.508
2.639AlaAsn: 2.639 ± 0.397
1.979AlaPro: 1.979 ± 0.41
3.958AlaGln: 3.958 ± 2.142
3.298AlaArg: 3.298 ± 1.573
1.979AlaSer: 1.979 ± 0.41
1.979AlaThr: 1.979 ± 1.871
3.958AlaVal: 3.958 ± 0.82
0.66AlaTrp: 0.66 ± 0.407
1.319AlaTyr: 1.319 ± 1.248
0.0AlaXaa: 0.0 ± 0.0
Cys
0.66CysAla: 0.66 ± 0.407
0.0CysCys: 0.0 ± 0.0
0.66CysAsp: 0.66 ± 0.407
0.66CysGlu: 0.66 ± 0.407
2.639CysPhe: 2.639 ± 1.531
0.66CysGly: 0.66 ± 0.407
1.979CysHis: 1.979 ± 0.733
1.979CysIle: 1.979 ± 1.287
3.298CysLys: 3.298 ± 0.963
1.319CysLeu: 1.319 ± 0.766
0.0CysMet: 0.0 ± 0.0
0.66CysAsn: 0.66 ± 0.812
0.0CysPro: 0.0 ± 0.0
0.66CysGln: 0.66 ± 0.407
1.319CysArg: 1.319 ± 0.814
1.319CysSer: 1.319 ± 0.517
1.319CysThr: 1.319 ± 0.766
0.66CysVal: 0.66 ± 0.812
1.319CysTrp: 1.319 ± 0.911
2.639CysTyr: 2.639 ± 1.531
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.66AspCys: 0.66 ± 0.572
0.66AspAsp: 0.66 ± 0.407
1.979AspGlu: 1.979 ± 0.699
2.639AspPhe: 2.639 ± 1.627
2.639AspGly: 2.639 ± 0.397
0.66AspHis: 0.66 ± 0.407
1.979AspIle: 1.979 ± 1.213
3.298AspLys: 3.298 ± 0.989
5.937AspLeu: 5.937 ± 1.051
1.319AspMet: 1.319 ± 0.517
1.319AspAsn: 1.319 ± 0.517
4.617AspPro: 4.617 ± 0.454
1.319AspGln: 1.319 ± 0.517
0.66AspArg: 0.66 ± 0.624
3.298AspSer: 3.298 ± 1.091
3.298AspThr: 3.298 ± 1.534
2.639AspVal: 2.639 ± 1.033
1.979AspTrp: 1.979 ± 1.488
1.979AspTyr: 1.979 ± 0.41
0.0AspXaa: 0.0 ± 0.0
Glu
6.596GluAla: 6.596 ± 2.323
5.277GluCys: 5.277 ± 1.502
4.617GluAsp: 4.617 ± 1.22
8.575GluGlu: 8.575 ± 0.784
3.958GluPhe: 3.958 ± 1.826
2.639GluGly: 2.639 ± 0.847
1.979GluHis: 1.979 ± 0.919
1.319GluIle: 1.319 ± 1.144
4.617GluLys: 4.617 ± 0.823
7.256GluLeu: 7.256 ± 1.793
0.0GluMet: 0.0 ± 0.0
4.617GluAsn: 4.617 ± 1.083
1.979GluPro: 1.979 ± 0.733
2.639GluGln: 2.639 ± 0.397
1.979GluArg: 1.979 ± 0.919
5.937GluSer: 5.937 ± 1.06
2.639GluThr: 2.639 ± 2.039
4.617GluVal: 4.617 ± 1.202
1.319GluTrp: 1.319 ± 0.766
1.979GluTyr: 1.979 ± 1.221
0.0GluXaa: 0.0 ± 0.0
Phe
3.298PheAla: 3.298 ± 0.428
1.979PheCys: 1.979 ± 0.919
1.979PheAsp: 1.979 ± 1.221
3.958PheGlu: 3.958 ± 0.82
1.979PhePhe: 1.979 ± 0.729
0.66PheGly: 0.66 ± 0.812
0.66PheHis: 0.66 ± 0.407
2.639PheIle: 2.639 ± 1.017
2.639PheLys: 2.639 ± 1.627
6.596PheLeu: 6.596 ± 1.926
0.0PheMet: 0.0 ± 0.0
1.979PheAsn: 1.979 ± 0.41
3.298PhePro: 3.298 ± 0.745
0.66PheGln: 0.66 ± 0.572
0.0PheArg: 0.0 ± 0.0
1.979PheSer: 1.979 ± 1.077
6.596PheThr: 6.596 ± 1.817
2.639PheVal: 2.639 ± 1.017
0.66PheTrp: 0.66 ± 0.624
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.596GlyAla: 6.596 ± 2.182
0.66GlyCys: 0.66 ± 0.407
2.639GlyAsp: 2.639 ± 0.847
3.298GlyGlu: 3.298 ± 1.806
2.639GlyPhe: 2.639 ± 1.792
5.937GlyGly: 5.937 ± 0.711
0.0GlyHis: 0.0 ± 0.0
2.639GlyIle: 2.639 ± 1.627
2.639GlyLys: 2.639 ± 1.198
7.256GlyLeu: 7.256 ± 1.846
1.319GlyMet: 1.319 ± 0.517
2.639GlyAsn: 2.639 ± 1.531
3.298GlyPro: 3.298 ± 0.694
3.298GlyGln: 3.298 ± 1.201
2.639GlyArg: 2.639 ± 1.648
2.639GlySer: 2.639 ± 1.428
1.319GlyThr: 1.319 ± 0.523
4.617GlyVal: 4.617 ± 1.758
0.0GlyTrp: 0.0 ± 0.0
1.319GlyTyr: 1.319 ± 1.144
0.0GlyXaa: 0.0 ± 0.0
His
1.979HisAla: 1.979 ± 1.006
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.979HisGlu: 1.979 ± 1.221
0.66HisPhe: 0.66 ± 0.572
1.319HisGly: 1.319 ± 0.714
0.66HisHis: 0.66 ± 0.407
0.0HisIle: 0.0 ± 0.0
2.639HisLys: 2.639 ± 0.818
3.298HisLeu: 3.298 ± 1.165
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.319HisPro: 1.319 ± 0.766
1.319HisGln: 1.319 ± 0.523
1.319HisArg: 1.319 ± 0.523
1.319HisSer: 1.319 ± 0.517
0.66HisThr: 0.66 ± 0.624
0.66HisVal: 0.66 ± 0.624
0.0HisTrp: 0.0 ± 0.0
2.639HisTyr: 2.639 ± 0.751
0.0HisXaa: 0.0 ± 0.0
Ile
3.298IleAla: 3.298 ± 1.054
1.319IleCys: 1.319 ± 0.814
1.979IleAsp: 1.979 ± 0.41
3.298IleGlu: 3.298 ± 1.386
1.319IlePhe: 1.319 ± 0.766
1.319IleGly: 1.319 ± 1.248
1.319IleHis: 1.319 ± 0.517
3.298IleIle: 3.298 ± 0.969
1.319IleLys: 1.319 ± 0.766
7.916IleLeu: 7.916 ± 1.616
1.319IleMet: 1.319 ± 0.766
1.979IleAsn: 1.979 ± 0.733
1.319IlePro: 1.319 ± 0.523
0.66IleGln: 0.66 ± 0.572
1.319IleArg: 1.319 ± 0.517
4.617IleSer: 4.617 ± 1.627
5.277IleThr: 5.277 ± 1.531
3.298IleVal: 3.298 ± 0.694
0.66IleTrp: 0.66 ± 0.812
2.639IleTyr: 2.639 ± 1.045
0.0IleXaa: 0.0 ± 0.0
Lys
1.979LysAla: 1.979 ± 0.733
1.319LysCys: 1.319 ± 0.766
1.319LysAsp: 1.319 ± 0.766
4.617LysGlu: 4.617 ± 2.392
0.66LysPhe: 0.66 ± 0.407
5.277LysGly: 5.277 ± 0.627
0.66LysHis: 0.66 ± 0.407
3.298LysIle: 3.298 ± 0.428
7.916LysLys: 7.916 ± 2.9
5.277LysLeu: 5.277 ± 1.531
1.979LysMet: 1.979 ± 0.733
5.277LysAsn: 5.277 ± 2.313
1.979LysPro: 1.979 ± 1.006
0.0LysGln: 0.0 ± 0.0
5.277LysArg: 5.277 ± 1.236
7.256LysSer: 7.256 ± 1.172
4.617LysThr: 4.617 ± 2.22
1.979LysVal: 1.979 ± 0.733
0.66LysTrp: 0.66 ± 0.407
2.639LysTyr: 2.639 ± 0.397
0.0LysXaa: 0.0 ± 0.0
Leu
4.617LeuAla: 4.617 ± 3.533
2.639LeuCys: 2.639 ± 1.067
5.277LeuAsp: 5.277 ± 2.001
7.916LeuGlu: 7.916 ± 2.661
5.937LeuPhe: 5.937 ± 1.687
5.277LeuGly: 5.277 ± 1.016
0.66LeuHis: 0.66 ± 0.624
5.937LeuIle: 5.937 ± 1.031
3.298LeuLys: 3.298 ± 0.969
13.193LeuLeu: 13.193 ± 1.485
3.958LeuMet: 3.958 ± 1.008
8.575LeuAsn: 8.575 ± 1.475
6.596LeuPro: 6.596 ± 1.665
5.277LeuGln: 5.277 ± 1.129
3.298LeuArg: 3.298 ± 0.428
7.916LeuSer: 7.916 ± 0.818
5.937LeuThr: 5.937 ± 1.641
1.979LeuVal: 1.979 ± 0.699
0.0LeuTrp: 0.0 ± 0.0
5.937LeuTyr: 5.937 ± 1.769
0.0LeuXaa: 0.0 ± 0.0
Met
2.639MetAla: 2.639 ± 0.847
1.319MetCys: 1.319 ± 0.766
1.979MetAsp: 1.979 ± 0.919
1.319MetGlu: 1.319 ± 0.517
0.0MetPhe: 0.0 ± 0.0
2.639MetGly: 2.639 ± 0.657
1.979MetHis: 1.979 ± 0.729
1.979MetIle: 1.979 ± 0.733
0.0MetLys: 0.0 ± 0.0
1.319MetLeu: 1.319 ± 0.523
0.0MetMet: 0.0 ± 0.0
1.319MetAsn: 1.319 ± 0.517
0.66MetPro: 0.66 ± 0.407
1.319MetGln: 1.319 ± 1.144
1.319MetArg: 1.319 ± 0.766
0.0MetSer: 0.0 ± 0.0
0.66MetThr: 0.66 ± 0.407
0.66MetVal: 0.66 ± 0.407
0.66MetTrp: 0.66 ± 0.572
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.639AsnAla: 2.639 ± 0.397
1.319AsnCys: 1.319 ± 0.517
2.639AsnAsp: 2.639 ± 1.033
3.958AsnGlu: 3.958 ± 2.023
1.979AsnPhe: 1.979 ± 0.832
0.66AsnGly: 0.66 ± 0.572
0.66AsnHis: 0.66 ± 0.812
4.617AsnIle: 4.617 ± 1.171
3.298AsnLys: 3.298 ± 0.963
6.596AsnLeu: 6.596 ± 1.915
2.639AsnMet: 2.639 ± 0.774
4.617AsnAsn: 4.617 ± 1.627
3.958AsnPro: 3.958 ± 1.458
1.979AsnGln: 1.979 ± 0.699
0.0AsnArg: 0.0 ± 0.0
0.66AsnSer: 0.66 ± 0.572
3.298AsnThr: 3.298 ± 1.501
3.298AsnVal: 3.298 ± 1.201
1.979AsnTrp: 1.979 ± 0.832
2.639AsnTyr: 2.639 ± 0.847
0.0AsnXaa: 0.0 ± 0.0
Pro
1.319ProAla: 1.319 ± 0.714
1.319ProCys: 1.319 ± 0.766
4.617ProAsp: 4.617 ± 1.462
7.916ProGlu: 7.916 ± 2.455
1.979ProPhe: 1.979 ± 0.699
3.958ProGly: 3.958 ± 0.82
0.66ProHis: 0.66 ± 0.624
1.979ProIle: 1.979 ± 0.41
3.958ProLys: 3.958 ± 2.023
3.958ProLeu: 3.958 ± 1.479
0.0ProMet: 0.0 ± 0.0
1.979ProAsn: 1.979 ± 0.41
7.256ProPro: 7.256 ± 2.452
2.639ProGln: 2.639 ± 1.017
1.979ProArg: 1.979 ± 1.134
3.298ProSer: 3.298 ± 1.383
1.979ProThr: 1.979 ± 0.733
3.298ProVal: 3.298 ± 2.121
0.0ProTrp: 0.0 ± 0.0
3.298ProTyr: 3.298 ± 0.428
0.0ProXaa: 0.0 ± 0.0
Gln
1.319GlnAla: 1.319 ± 0.523
0.0GlnCys: 0.0 ± 0.0
1.979GlnAsp: 1.979 ± 0.733
1.979GlnGlu: 1.979 ± 0.699
2.639GlnPhe: 2.639 ± 1.033
2.639GlnGly: 2.639 ± 1.56
1.319GlnHis: 1.319 ± 0.523
1.319GlnIle: 1.319 ± 0.517
2.639GlnLys: 2.639 ± 1.017
5.937GlnLeu: 5.937 ± 1.679
0.66GlnMet: 0.66 ± 0.572
1.319GlnAsn: 1.319 ± 0.517
1.979GlnPro: 1.979 ± 0.733
3.958GlnGln: 3.958 ± 1.063
3.958GlnArg: 3.958 ± 1.629
3.298GlnSer: 3.298 ± 0.691
2.639GlnThr: 2.639 ± 0.847
3.958GlnVal: 3.958 ± 1.858
0.0GlnTrp: 0.0 ± 0.0
1.979GlnTyr: 1.979 ± 1.077
0.0GlnXaa: 0.0 ± 0.0
Arg
1.979ArgAla: 1.979 ± 1.213
0.66ArgCys: 0.66 ± 0.407
1.319ArgAsp: 1.319 ± 0.814
3.298ArgGlu: 3.298 ± 0.963
2.639ArgPhe: 2.639 ± 1.045
0.66ArgGly: 0.66 ± 0.572
2.639ArgHis: 2.639 ± 1.045
2.639ArgIle: 2.639 ± 1.067
5.277ArgLys: 5.277 ± 2.394
3.298ArgLeu: 3.298 ± 1.054
1.979ArgMet: 1.979 ± 0.729
1.319ArgAsn: 1.319 ± 0.766
1.319ArgPro: 1.319 ± 1.248
0.66ArgGln: 0.66 ± 0.624
2.639ArgArg: 2.639 ± 1.68
3.298ArgSer: 3.298 ± 0.694
0.66ArgThr: 0.66 ± 0.624
3.298ArgVal: 3.298 ± 1.439
1.319ArgTrp: 1.319 ± 0.523
3.298ArgTyr: 3.298 ± 2.191
0.0ArgXaa: 0.0 ± 0.0
Ser
8.575SerAla: 8.575 ± 2.059
0.0SerCys: 0.0 ± 0.0
1.979SerAsp: 1.979 ± 1.011
4.617SerGlu: 4.617 ± 0.697
3.298SerPhe: 3.298 ± 0.969
1.319SerGly: 1.319 ± 0.517
1.979SerHis: 1.979 ± 0.41
2.639SerIle: 2.639 ± 1.045
2.639SerLys: 2.639 ± 0.397
6.596SerLeu: 6.596 ± 1.903
0.66SerMet: 0.66 ± 0.572
3.958SerAsn: 3.958 ± 0.761
3.298SerPro: 3.298 ± 0.745
6.596SerGln: 6.596 ± 1.177
3.958SerArg: 3.958 ± 1.899
5.937SerSer: 5.937 ± 1.06
3.958SerThr: 3.958 ± 1.208
1.979SerVal: 1.979 ± 0.41
1.319SerTrp: 1.319 ± 0.523
1.319SerTyr: 1.319 ± 1.248
0.0SerXaa: 0.0 ± 0.0
Thr
1.979ThrAla: 1.979 ± 0.733
0.66ThrCys: 0.66 ± 0.572
1.319ThrAsp: 1.319 ± 0.523
4.617ThrGlu: 4.617 ± 1.453
1.319ThrPhe: 1.319 ± 0.814
5.277ThrGly: 5.277 ± 0.716
0.66ThrHis: 0.66 ± 0.624
1.979ThrIle: 1.979 ± 0.733
0.66ThrLys: 0.66 ± 0.407
6.596ThrLeu: 6.596 ± 1.245
0.66ThrMet: 0.66 ± 0.572
2.639ThrAsn: 2.639 ± 0.847
5.937ThrPro: 5.937 ± 1.06
3.298ThrGln: 3.298 ± 0.694
1.979ThrArg: 1.979 ± 1.006
3.958ThrSer: 3.958 ± 1.629
5.277ThrThr: 5.277 ± 0.34
5.277ThrVal: 5.277 ± 1.016
1.979ThrTrp: 1.979 ± 2.436
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.979ValAla: 1.979 ± 1.213
1.319ValCys: 1.319 ± 0.766
2.639ValAsp: 2.639 ± 0.921
3.298ValGlu: 3.298 ± 0.969
1.319ValPhe: 1.319 ± 0.523
3.298ValGly: 3.298 ± 2.121
1.319ValHis: 1.319 ± 0.523
2.639ValIle: 2.639 ± 1.033
4.617ValLys: 4.617 ± 1.698
3.298ValLeu: 3.298 ± 1.091
0.66ValMet: 0.66 ± 0.572
5.277ValAsn: 5.277 ± 1.851
4.617ValPro: 4.617 ± 2.004
1.979ValGln: 1.979 ± 0.733
2.639ValArg: 2.639 ± 1.428
5.277ValSer: 5.277 ± 0.794
2.639ValThr: 2.639 ± 0.397
2.639ValVal: 2.639 ± 0.847
0.66ValTrp: 0.66 ± 0.624
1.979ValTyr: 1.979 ± 1.011
0.0ValXaa: 0.0 ± 0.0
Trp
1.319TrpAla: 1.319 ± 1.248
0.66TrpCys: 0.66 ± 0.812
0.66TrpAsp: 0.66 ± 0.407
3.298TrpGlu: 3.298 ± 1.518
1.319TrpPhe: 1.319 ± 1.624
0.66TrpGly: 0.66 ± 0.812
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.979TrpLys: 1.979 ± 0.919
0.66TrpLeu: 0.66 ± 0.812
1.319TrpMet: 1.319 ± 0.523
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.319TrpGln: 1.319 ± 0.766
1.319TrpArg: 1.319 ± 1.023
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.66TrpVal: 0.66 ± 0.572
0.66TrpTrp: 0.66 ± 0.407
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.319TyrAla: 1.319 ± 0.523
1.979TyrCys: 1.979 ± 1.525
1.979TyrAsp: 1.979 ± 1.077
0.0TyrGlu: 0.0 ± 0.0
2.639TyrPhe: 2.639 ± 1.792
5.277TyrGly: 5.277 ± 0.34
1.979TyrHis: 1.979 ± 1.006
1.319TyrIle: 1.319 ± 1.023
2.639TyrLys: 2.639 ± 1.198
1.979TyrLeu: 1.979 ± 0.699
1.979TyrMet: 1.979 ± 1.221
1.319TyrAsn: 1.319 ± 0.517
1.979TyrPro: 1.979 ± 1.716
1.979TyrGln: 1.979 ± 0.733
3.298TyrArg: 3.298 ± 1.501
2.639TyrSer: 2.639 ± 1.428
1.319TyrThr: 1.319 ± 0.523
1.979TyrVal: 1.979 ± 0.699
0.0TyrTrp: 0.0 ± 0.0
2.639TyrTyr: 2.639 ± 1.428
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1517 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski