Amino acid dipepetide frequency for Botrytis virus X (isolate Botrytis cinerea/New Zealand/Howitt/2006) (BOTV-X)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.915AlaAla: 11.915 ± 5.795
1.702AlaCys: 1.702 ± 0.792
3.83AlaAsp: 3.83 ± 1.597
5.532AlaGlu: 5.532 ± 1.575
2.128AlaPhe: 2.128 ± 1.518
5.957AlaGly: 5.957 ± 1.953
5.106AlaHis: 5.106 ± 3.172
2.979AlaIle: 2.979 ± 1.408
6.809AlaLys: 6.809 ± 1.654
10.213AlaLeu: 10.213 ± 1.692
1.277AlaMet: 1.277 ± 0.508
4.255AlaAsn: 4.255 ± 1.435
5.532AlaPro: 5.532 ± 2.003
3.83AlaGln: 3.83 ± 1.538
4.681AlaArg: 4.681 ± 1.731
4.681AlaSer: 4.681 ± 1.394
4.681AlaThr: 4.681 ± 0.534
6.383AlaVal: 6.383 ± 1.73
0.0AlaTrp: 0.0 ± 0.0
3.404AlaTyr: 3.404 ± 1.369
0.0AlaXaa: 0.0 ± 0.0
Cys
1.702CysAla: 1.702 ± 0.53
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.426CysGlu: 0.426 ± 0.237
0.0CysPhe: 0.0 ± 0.0
1.277CysGly: 1.277 ± 0.658
0.426CysHis: 0.426 ± 0.629
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.851CysLeu: 0.851 ± 0.928
0.0CysMet: 0.0 ± 0.0
0.426CysAsn: 0.426 ± 0.237
0.851CysPro: 0.851 ± 0.543
0.426CysGln: 0.426 ± 0.237
0.851CysArg: 0.851 ± 0.474
1.277CysSer: 1.277 ± 0.658
2.553CysThr: 2.553 ± 1.421
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.426CysTyr: 0.426 ± 0.237
0.0CysXaa: 0.0 ± 0.0
Asp
5.957AspAla: 5.957 ± 1.063
0.426AspCys: 0.426 ± 0.237
5.106AspAsp: 5.106 ± 1.909
3.83AspGlu: 3.83 ± 1.418
3.83AspPhe: 3.83 ± 0.565
2.553AspGly: 2.553 ± 0.954
1.702AspHis: 1.702 ± 1.279
4.681AspIle: 4.681 ± 1.553
2.979AspLys: 2.979 ± 0.83
4.681AspLeu: 4.681 ± 1.128
0.426AspMet: 0.426 ± 0.454
3.404AspAsn: 3.404 ± 0.882
4.681AspPro: 4.681 ± 0.716
1.277AspGln: 1.277 ± 0.886
1.702AspArg: 1.702 ± 0.947
2.979AspSer: 2.979 ± 1.148
4.255AspThr: 4.255 ± 1.073
2.979AspVal: 2.979 ± 1.211
1.702AspTrp: 1.702 ± 0.66
1.702AspTyr: 1.702 ± 0.53
0.0AspXaa: 0.0 ± 0.0
Glu
3.83GluAla: 3.83 ± 1.145
0.426GluCys: 0.426 ± 0.237
0.851GluAsp: 0.851 ± 0.474
3.404GluGlu: 3.404 ± 1.585
1.277GluPhe: 1.277 ± 0.403
0.851GluGly: 0.851 ± 0.474
1.702GluHis: 1.702 ± 0.573
2.979GluIle: 2.979 ± 1.291
2.553GluLys: 2.553 ± 1.062
8.085GluLeu: 8.085 ± 1.395
1.702GluMet: 1.702 ± 0.684
0.851GluAsn: 0.851 ± 0.474
3.83GluPro: 3.83 ± 0.443
1.277GluGln: 1.277 ± 0.403
1.702GluArg: 1.702 ± 0.947
1.277GluSer: 1.277 ± 0.71
3.83GluThr: 3.83 ± 2.131
2.128GluVal: 2.128 ± 1.184
0.426GluTrp: 0.426 ± 0.629
1.702GluTyr: 1.702 ± 0.476
0.0GluXaa: 0.0 ± 0.0
Phe
2.979PheAla: 2.979 ± 1.115
0.851PheCys: 0.851 ± 0.396
2.128PheAsp: 2.128 ± 0.783
2.553PheGlu: 2.553 ± 0.923
1.702PhePhe: 1.702 ± 0.88
0.851PheGly: 0.851 ± 0.474
2.979PheHis: 2.979 ± 0.531
2.553PheIle: 2.553 ± 0.664
3.404PheLys: 3.404 ± 0.426
2.553PheLeu: 2.553 ± 0.954
0.426PheMet: 0.426 ± 0.237
1.277PheAsn: 1.277 ± 0.529
2.128PhePro: 2.128 ± 0.67
0.851PheGln: 0.851 ± 0.474
1.277PheArg: 1.277 ± 0.403
3.83PheSer: 3.83 ± 1.221
4.681PheThr: 4.681 ± 0.872
2.128PheVal: 2.128 ± 1.184
0.0PheTrp: 0.0 ± 0.0
1.277PheTyr: 1.277 ± 0.605
0.0PheXaa: 0.0 ± 0.0
Gly
2.979GlyAla: 2.979 ± 0.407
0.426GlyCys: 0.426 ± 0.237
3.83GlyAsp: 3.83 ± 0.979
1.702GlyGlu: 1.702 ± 1.194
2.128GlyPhe: 2.128 ± 1.198
3.404GlyGly: 3.404 ± 1.302
2.979GlyHis: 2.979 ± 1.143
2.553GlyIle: 2.553 ± 0.389
3.404GlyLys: 3.404 ± 1.369
3.404GlyLeu: 3.404 ± 0.882
0.426GlyMet: 0.426 ± 0.237
0.426GlyAsn: 0.426 ± 0.513
4.255GlyPro: 4.255 ± 1.57
1.277GlyGln: 1.277 ± 0.605
0.851GlyArg: 0.851 ± 0.474
2.979GlySer: 2.979 ± 1.507
2.553GlyThr: 2.553 ± 0.598
2.128GlyVal: 2.128 ± 0.714
0.851GlyTrp: 0.851 ± 0.396
1.277GlyTyr: 1.277 ± 0.403
0.0GlyXaa: 0.0 ± 0.0
His
5.106HisAla: 5.106 ± 0.943
0.851HisCys: 0.851 ± 0.806
1.277HisAsp: 1.277 ± 0.71
0.851HisGlu: 0.851 ± 0.396
2.128HisPhe: 2.128 ± 1.184
3.404HisGly: 3.404 ± 0.918
2.979HisHis: 2.979 ± 1.855
3.83HisIle: 3.83 ± 1.278
0.851HisLys: 0.851 ± 0.47
3.404HisLeu: 3.404 ± 0.951
0.426HisMet: 0.426 ± 0.237
2.979HisAsn: 2.979 ± 0.407
3.404HisPro: 3.404 ± 2.685
2.553HisGln: 2.553 ± 0.807
1.702HisArg: 1.702 ± 0.655
2.128HisSer: 2.128 ± 1.351
2.553HisThr: 2.553 ± 0.389
2.128HisVal: 2.128 ± 1.022
0.426HisTrp: 0.426 ± 0.237
0.426HisTyr: 0.426 ± 0.513
0.0HisXaa: 0.0 ± 0.0
Ile
5.532IleAla: 5.532 ± 1.924
0.0IleCys: 0.0 ± 0.0
3.404IleAsp: 3.404 ± 1.756
0.426IleGlu: 0.426 ± 0.513
2.553IlePhe: 2.553 ± 1.21
2.128IleGly: 2.128 ± 1.191
0.851IleHis: 0.851 ± 0.47
1.702IleIle: 1.702 ± 1.279
3.404IleLys: 3.404 ± 1.002
2.979IleLeu: 2.979 ± 0.531
1.277IleMet: 1.277 ± 0.529
3.404IleAsn: 3.404 ± 0.581
4.255IlePro: 4.255 ± 1.207
2.553IleGln: 2.553 ± 0.923
3.404IleArg: 3.404 ± 1.88
4.255IleSer: 4.255 ± 0.951
3.83IleThr: 3.83 ± 1.047
2.553IleVal: 2.553 ± 1.058
0.0IleTrp: 0.0 ± 0.0
0.426IleTyr: 0.426 ± 0.751
0.0IleXaa: 0.0 ± 0.0
Lys
4.255LysAla: 4.255 ± 0.674
0.0LysCys: 0.0 ± 0.0
4.255LysAsp: 4.255 ± 1.119
2.979LysGlu: 2.979 ± 0.83
0.851LysPhe: 0.851 ± 0.396
0.426LysGly: 0.426 ± 0.513
2.128LysHis: 2.128 ± 0.764
2.128LysIle: 2.128 ± 1.184
1.277LysLys: 1.277 ± 0.71
5.106LysLeu: 5.106 ± 2.241
2.128LysMet: 2.128 ± 0.637
1.702LysAsn: 1.702 ± 0.53
2.553LysPro: 2.553 ± 0.676
1.702LysGln: 1.702 ± 0.655
1.277LysArg: 1.277 ± 0.403
3.404LysSer: 3.404 ± 1.018
5.957LysThr: 5.957 ± 0.937
4.681LysVal: 4.681 ± 0.5
0.426LysTrp: 0.426 ± 0.237
0.851LysTyr: 0.851 ± 0.47
0.0LysXaa: 0.0 ± 0.0
Leu
6.809LeuAla: 6.809 ± 1.551
0.851LeuCys: 0.851 ± 0.474
7.234LeuAsp: 7.234 ± 0.564
2.979LeuGlu: 2.979 ± 1.657
4.681LeuPhe: 4.681 ± 1.815
2.979LeuGly: 2.979 ± 1.657
6.383LeuHis: 6.383 ± 1.444
6.809LeuIle: 6.809 ± 4.348
4.681LeuLys: 4.681 ± 1.455
8.085LeuLeu: 8.085 ± 2.072
2.128LeuMet: 2.128 ± 0.999
5.532LeuAsn: 5.532 ± 1.528
7.234LeuPro: 7.234 ± 3.105
2.553LeuGln: 2.553 ± 1.918
7.234LeuArg: 7.234 ± 0.86
6.809LeuSer: 6.809 ± 2.214
9.787LeuThr: 9.787 ± 3.764
4.255LeuVal: 4.255 ± 1.435
0.851LeuTrp: 0.851 ± 0.474
2.553LeuTyr: 2.553 ± 0.692
0.0LeuXaa: 0.0 ± 0.0
Met
1.277MetAla: 1.277 ± 0.403
0.426MetCys: 0.426 ± 0.237
1.277MetAsp: 1.277 ± 0.886
0.851MetGlu: 0.851 ± 0.47
0.0MetPhe: 0.0 ± 0.0
0.426MetGly: 0.426 ± 0.237
0.851MetHis: 0.851 ± 0.47
0.851MetIle: 0.851 ± 0.543
1.277MetLys: 1.277 ± 0.553
2.128MetLeu: 2.128 ± 0.815
0.0MetMet: 0.0 ± 0.0
0.426MetAsn: 0.426 ± 0.513
2.128MetPro: 2.128 ± 0.882
0.851MetGln: 0.851 ± 0.474
1.277MetArg: 1.277 ± 0.71
2.553MetSer: 2.553 ± 1.115
0.851MetThr: 0.851 ± 0.474
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.851MetTyr: 0.851 ± 0.543
0.0MetXaa: 0.0 ± 0.0
Asn
4.255AsnAla: 4.255 ± 1.878
0.851AsnCys: 0.851 ± 0.474
3.83AsnAsp: 3.83 ± 1.145
1.277AsnGlu: 1.277 ± 0.403
1.702AsnPhe: 1.702 ± 0.66
1.277AsnGly: 1.277 ± 0.403
0.851AsnHis: 0.851 ± 0.806
1.702AsnIle: 1.702 ± 0.88
1.277AsnLys: 1.277 ± 0.403
3.404AsnLeu: 3.404 ± 0.896
0.0AsnMet: 0.0 ± 0.0
0.851AsnAsn: 0.851 ± 0.639
3.83AsnPro: 3.83 ± 2.131
1.277AsnGln: 1.277 ± 0.605
2.128AsnArg: 2.128 ± 1.184
2.128AsnSer: 2.128 ± 1.2
3.404AsnThr: 3.404 ± 1.671
4.681AsnVal: 4.681 ± 1.128
0.426AsnTrp: 0.426 ± 0.513
1.702AsnTyr: 1.702 ± 0.53
0.0AsnXaa: 0.0 ± 0.0
Pro
8.085ProAla: 8.085 ± 3.111
0.426ProCys: 0.426 ± 0.629
6.809ProAsp: 6.809 ± 1.267
3.404ProGlu: 3.404 ± 1.059
2.979ProPhe: 2.979 ± 1.243
3.404ProGly: 3.404 ± 1.186
1.702ProHis: 1.702 ± 1.279
2.979ProIle: 2.979 ± 0.987
4.681ProLys: 4.681 ± 1.019
5.532ProLeu: 5.532 ± 0.457
0.851ProMet: 0.851 ± 0.474
2.979ProAsn: 2.979 ± 1.462
12.766ProPro: 12.766 ± 5.459
2.553ProGln: 2.553 ± 0.562
2.128ProArg: 2.128 ± 0.714
5.106ProSer: 5.106 ± 2.846
13.191ProThr: 13.191 ± 6.463
3.404ProVal: 3.404 ± 1.059
0.426ProTrp: 0.426 ± 0.524
1.702ProTyr: 1.702 ± 0.66
0.0ProXaa: 0.0 ± 0.0
Gln
4.681GlnAla: 4.681 ± 1.427
0.426GlnCys: 0.426 ± 0.237
2.128GlnAsp: 2.128 ± 0.764
1.702GlnGlu: 1.702 ± 0.53
2.553GlnPhe: 2.553 ± 0.923
1.702GlnGly: 1.702 ± 0.53
0.426GlnHis: 0.426 ± 0.237
2.128GlnIle: 2.128 ± 0.364
0.0GlnLys: 0.0 ± 0.0
5.532GlnLeu: 5.532 ± 0.786
0.0GlnMet: 0.0 ± 0.0
0.426GlnAsn: 0.426 ± 0.237
3.83GlnPro: 3.83 ± 1.144
1.277GlnGln: 1.277 ± 0.403
1.277GlnArg: 1.277 ± 1.375
0.851GlnSer: 0.851 ± 0.396
2.128GlnThr: 2.128 ± 0.785
1.702GlnVal: 1.702 ± 0.792
0.426GlnTrp: 0.426 ± 0.237
1.702GlnTyr: 1.702 ± 0.476
0.0GlnXaa: 0.0 ± 0.0
Arg
5.106ArgAla: 5.106 ± 0.836
0.851ArgCys: 0.851 ± 0.47
2.553ArgAsp: 2.553 ± 0.954
2.128ArgGlu: 2.128 ± 0.856
1.702ArgPhe: 1.702 ± 0.53
1.277ArgGly: 1.277 ± 0.801
2.128ArgHis: 2.128 ± 0.58
1.702ArgIle: 1.702 ± 0.66
2.128ArgLys: 2.128 ± 0.714
3.83ArgLeu: 3.83 ± 1.759
1.702ArgMet: 1.702 ± 0.726
2.979ArgAsn: 2.979 ± 1.657
3.404ArgPro: 3.404 ± 1.002
4.255ArgGln: 4.255 ± 0.725
1.277ArgArg: 1.277 ± 0.403
0.851ArgSer: 0.851 ± 0.474
2.128ArgThr: 2.128 ± 0.764
2.128ArgVal: 2.128 ± 0.714
0.426ArgTrp: 0.426 ± 0.513
1.702ArgTyr: 1.702 ± 1.393
0.0ArgXaa: 0.0 ± 0.0
Ser
4.255SerAla: 4.255 ± 1.278
1.277SerCys: 1.277 ± 1.888
5.106SerAsp: 5.106 ± 1.879
2.128SerGlu: 2.128 ± 0.637
2.128SerPhe: 2.128 ± 1.184
3.83SerGly: 3.83 ± 1.221
1.277SerHis: 1.277 ± 0.403
2.979SerIle: 2.979 ± 1.795
1.277SerLys: 1.277 ± 0.71
9.787SerLeu: 9.787 ± 4.125
1.702SerMet: 1.702 ± 0.895
2.553SerAsn: 2.553 ± 0.692
3.83SerPro: 3.83 ± 2.872
1.702SerGln: 1.702 ± 0.711
4.255SerArg: 4.255 ± 1.528
5.532SerSer: 5.532 ± 3.283
5.106SerThr: 5.106 ± 1.812
2.553SerVal: 2.553 ± 2.201
0.851SerTrp: 0.851 ± 0.474
2.553SerTyr: 2.553 ± 0.954
0.0SerXaa: 0.0 ± 0.0
Thr
7.234ThrAla: 7.234 ± 1.116
0.426ThrCys: 0.426 ± 0.513
2.553ThrAsp: 2.553 ± 0.721
3.404ThrGlu: 3.404 ± 1.319
4.681ThrPhe: 4.681 ± 0.894
4.255ThrGly: 4.255 ± 1.566
3.83ThrHis: 3.83 ± 0.78
2.553ThrIle: 2.553 ± 0.676
2.979ThrLys: 2.979 ± 1.657
11.489ThrLeu: 11.489 ± 2.343
2.128ThrMet: 2.128 ± 0.58
2.979ThrAsn: 2.979 ± 0.421
11.489ThrPro: 11.489 ± 5.358
1.702ThrGln: 1.702 ± 0.66
5.106ThrArg: 5.106 ± 1.355
7.234ThrSer: 7.234 ± 1.643
7.234ThrThr: 7.234 ± 2.379
3.404ThrVal: 3.404 ± 0.432
0.0ThrTrp: 0.0 ± 0.0
2.979ThrTyr: 2.979 ± 0.76
0.0ThrXaa: 0.0 ± 0.0
Val
2.553ValAla: 2.553 ± 0.598
0.426ValCys: 0.426 ± 0.524
2.128ValAsp: 2.128 ± 0.951
4.681ValGlu: 4.681 ± 1.6
1.702ValPhe: 1.702 ± 0.947
2.979ValGly: 2.979 ± 0.531
2.979ValHis: 2.979 ± 0.839
2.979ValIle: 2.979 ± 0.964
4.255ValLys: 4.255 ± 1.306
5.532ValLeu: 5.532 ± 1.836
0.851ValMet: 0.851 ± 0.806
1.702ValAsn: 1.702 ± 0.476
3.404ValPro: 3.404 ± 1.354
1.277ValGln: 1.277 ± 0.71
0.851ValArg: 0.851 ± 0.396
2.979ValSer: 2.979 ± 1.425
5.532ValThr: 5.532 ± 1.096
1.702ValVal: 1.702 ± 0.668
0.851ValTrp: 0.851 ± 0.866
0.851ValTyr: 0.851 ± 0.47
0.0ValXaa: 0.0 ± 0.0
Trp
0.851TrpAla: 0.851 ± 0.396
0.0TrpCys: 0.0 ± 0.0
0.426TrpAsp: 0.426 ± 0.237
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.426TrpGly: 0.426 ± 0.513
0.426TrpHis: 0.426 ± 0.751
0.0TrpIle: 0.0 ± 0.0
0.426TrpLys: 0.426 ± 0.237
0.851TrpLeu: 0.851 ± 0.474
0.0TrpMet: 0.0 ± 0.0
1.277TrpAsn: 1.277 ± 0.773
0.426TrpPro: 0.426 ± 0.751
0.851TrpGln: 0.851 ± 0.396
0.426TrpArg: 0.426 ± 0.524
1.277TrpSer: 1.277 ± 0.71
0.0TrpThr: 0.0 ± 0.0
0.426TrpVal: 0.426 ± 0.237
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.532TyrAla: 5.532 ± 1.079
0.851TyrCys: 0.851 ± 0.543
2.553TyrAsp: 2.553 ± 1.189
0.426TyrGlu: 0.426 ± 0.237
1.702TyrPhe: 1.702 ± 0.792
0.426TyrGly: 0.426 ± 0.237
1.702TyrHis: 1.702 ± 0.66
0.851TyrIle: 0.851 ± 0.474
0.426TyrLys: 0.426 ± 0.237
2.979TyrLeu: 2.979 ± 1.243
0.426TyrMet: 0.426 ± 0.237
0.426TyrAsn: 0.426 ± 0.751
1.277TyrPro: 1.277 ± 0.71
0.851TyrGln: 0.851 ± 0.396
0.851TyrArg: 0.851 ± 0.47
2.553TyrSer: 2.553 ± 1.193
3.404TyrThr: 3.404 ± 1.155
0.851TyrVal: 0.851 ± 1.009
0.0TyrTrp: 0.0 ± 0.0
0.851TyrTyr: 0.851 ± 0.474
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2351 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski