Amino acid dipepetide frequency for Rotavirus C (isolate RVC/Human/United Kingdom/Bristol/1989) (RV-C)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.102AlaAla: 4.102 ± 0.731
1.07AlaCys: 1.07 ± 0.489
1.962AlaAsp: 1.962 ± 0.468
2.675AlaGlu: 2.675 ± 0.862
2.319AlaPhe: 2.319 ± 0.451
2.675AlaGly: 2.675 ± 0.552
0.892AlaHis: 0.892 ± 0.305
5.35AlaIle: 5.35 ± 0.638
3.745AlaLys: 3.745 ± 0.82
5.529AlaLeu: 5.529 ± 1.043
2.319AlaMet: 2.319 ± 0.415
2.854AlaAsn: 2.854 ± 0.423
1.427AlaPro: 1.427 ± 0.404
1.962AlaGln: 1.962 ± 0.54
1.962AlaArg: 1.962 ± 0.479
4.459AlaSer: 4.459 ± 1.109
3.21AlaThr: 3.21 ± 0.421
2.675AlaVal: 2.675 ± 0.671
0.178AlaTrp: 0.178 ± 0.144
1.783AlaTyr: 1.783 ± 0.316
0.0AlaXaa: 0.0 ± 0.0
Cys
0.535CysAla: 0.535 ± 0.344
0.0CysCys: 0.0 ± 0.0
1.427CysAsp: 1.427 ± 0.702
0.535CysGlu: 0.535 ± 0.292
0.713CysPhe: 0.713 ± 0.317
0.357CysGly: 0.357 ± 0.277
0.357CysHis: 0.357 ± 0.24
1.962CysIle: 1.962 ± 0.905
1.248CysLys: 1.248 ± 0.53
1.605CysLeu: 1.605 ± 0.745
0.535CysMet: 0.535 ± 0.217
0.535CysAsn: 0.535 ± 0.323
0.713CysPro: 0.713 ± 0.465
0.892CysGln: 0.892 ± 0.419
0.178CysArg: 0.178 ± 0.216
0.892CysSer: 0.892 ± 0.525
0.535CysThr: 0.535 ± 0.3
0.892CysVal: 0.892 ± 0.417
0.0CysTrp: 0.0 ± 0.0
0.178CysTyr: 0.178 ± 0.18
0.0CysXaa: 0.0 ± 0.0
Asp
3.21AspAla: 3.21 ± 0.78
0.892AspCys: 0.892 ± 0.438
3.567AspAsp: 3.567 ± 0.727
2.497AspGlu: 2.497 ± 1.076
2.497AspPhe: 2.497 ± 0.582
3.745AspGly: 3.745 ± 0.57
0.892AspHis: 0.892 ± 0.46
6.242AspIle: 6.242 ± 1.193
3.032AspLys: 3.032 ± 0.802
3.032AspLeu: 3.032 ± 0.706
1.783AspMet: 1.783 ± 0.517
3.567AspAsn: 3.567 ± 0.588
1.248AspPro: 1.248 ± 0.288
1.605AspGln: 1.605 ± 0.416
1.605AspArg: 1.605 ± 0.529
4.459AspSer: 4.459 ± 0.695
3.567AspThr: 3.567 ± 0.72
3.745AspVal: 3.745 ± 0.614
0.357AspTrp: 0.357 ± 0.336
4.637AspTyr: 4.637 ± 0.687
0.0AspXaa: 0.0 ± 0.0
Glu
2.319GluAla: 2.319 ± 0.709
0.892GluCys: 0.892 ± 0.62
2.14GluAsp: 2.14 ± 0.501
3.21GluGlu: 3.21 ± 0.829
2.319GluPhe: 2.319 ± 0.567
1.427GluGly: 1.427 ± 0.329
0.892GluHis: 0.892 ± 0.388
5.707GluIle: 5.707 ± 0.803
5.707GluLys: 5.707 ± 1.317
4.637GluLeu: 4.637 ± 0.893
2.854GluMet: 2.854 ± 0.846
4.994GluAsn: 4.994 ± 0.966
0.357GluPro: 0.357 ± 0.254
0.892GluGln: 0.892 ± 0.519
3.032GluArg: 3.032 ± 0.694
4.637GluSer: 4.637 ± 1.366
2.675GluThr: 2.675 ± 0.912
2.675GluVal: 2.675 ± 0.677
1.605GluTrp: 1.605 ± 0.556
3.032GluTyr: 3.032 ± 0.871
0.0GluXaa: 0.0 ± 0.0
Phe
2.319PheAla: 2.319 ± 0.478
0.178PheCys: 0.178 ± 0.187
3.567PheAsp: 3.567 ± 0.574
2.497PheGlu: 2.497 ± 0.461
0.713PhePhe: 0.713 ± 0.324
1.783PheGly: 1.783 ± 0.451
0.892PheHis: 0.892 ± 0.28
4.459PheIle: 4.459 ± 0.966
4.459PheLys: 4.459 ± 0.63
2.675PheLeu: 2.675 ± 0.845
0.892PheMet: 0.892 ± 0.444
3.389PheAsn: 3.389 ± 0.777
1.427PhePro: 1.427 ± 0.594
1.427PheGln: 1.427 ± 0.625
1.962PheArg: 1.962 ± 0.589
3.567PheSer: 3.567 ± 0.617
3.389PheThr: 3.389 ± 0.786
1.962PheVal: 1.962 ± 0.505
0.357PheTrp: 0.357 ± 0.218
1.07PheTyr: 1.07 ± 0.289
0.0PheXaa: 0.0 ± 0.0
Gly
1.248GlyAla: 1.248 ± 0.293
0.535GlyCys: 0.535 ± 0.325
2.14GlyAsp: 2.14 ± 0.405
1.962GlyGlu: 1.962 ± 0.36
1.07GlyPhe: 1.07 ± 0.357
2.14GlyGly: 2.14 ± 0.834
0.892GlyHis: 0.892 ± 0.432
4.637GlyIle: 4.637 ± 0.911
2.319GlyLys: 2.319 ± 0.443
2.675GlyLeu: 2.675 ± 0.624
1.427GlyMet: 1.427 ± 0.497
1.962GlyAsn: 1.962 ± 0.54
1.07GlyPro: 1.07 ± 0.516
1.605GlyGln: 1.605 ± 0.529
2.319GlyArg: 2.319 ± 0.611
3.389GlySer: 3.389 ± 1.032
2.854GlyThr: 2.854 ± 0.876
1.427GlyVal: 1.427 ± 0.427
0.892GlyTrp: 0.892 ± 0.345
1.962GlyTyr: 1.962 ± 0.788
0.0GlyXaa: 0.0 ± 0.0
His
1.07HisAla: 1.07 ± 0.329
0.357HisCys: 0.357 ± 0.162
1.427HisAsp: 1.427 ± 0.429
1.427HisGlu: 1.427 ± 0.531
0.535HisPhe: 0.535 ± 0.277
0.713HisGly: 0.713 ± 0.415
0.713HisHis: 0.713 ± 0.271
1.07HisIle: 1.07 ± 0.699
1.07HisLys: 1.07 ± 0.313
1.427HisLeu: 1.427 ± 0.567
0.178HisMet: 0.178 ± 0.219
1.427HisAsn: 1.427 ± 0.545
0.357HisPro: 0.357 ± 0.263
0.178HisGln: 0.178 ± 0.156
0.713HisArg: 0.713 ± 0.519
1.962HisSer: 1.962 ± 0.44
1.427HisThr: 1.427 ± 0.571
1.427HisVal: 1.427 ± 0.49
0.178HisTrp: 0.178 ± 0.216
0.535HisTyr: 0.535 ± 0.278
0.0HisXaa: 0.0 ± 0.0
Ile
4.459IleAla: 4.459 ± 1.204
1.605IleCys: 1.605 ± 0.579
4.815IleAsp: 4.815 ± 0.696
5.172IleGlu: 5.172 ± 0.694
3.032IlePhe: 3.032 ± 0.612
2.675IleGly: 2.675 ± 0.706
1.427IleHis: 1.427 ± 0.579
6.599IleIle: 6.599 ± 1.046
5.529IleLys: 5.529 ± 0.95
8.204IleLeu: 8.204 ± 1.227
2.497IleMet: 2.497 ± 0.792
9.988IleAsn: 9.988 ± 1.388
3.924IlePro: 3.924 ± 0.846
2.675IleGln: 2.675 ± 0.828
3.032IleArg: 3.032 ± 0.616
6.599IleSer: 6.599 ± 0.832
6.242IleThr: 6.242 ± 0.967
5.886IleVal: 5.886 ± 0.682
0.535IleTrp: 0.535 ± 0.278
3.21IleTyr: 3.21 ± 0.988
0.0IleXaa: 0.0 ± 0.0
Lys
3.567LysAla: 3.567 ± 0.896
0.357LysCys: 0.357 ± 0.374
3.389LysAsp: 3.389 ± 0.593
3.924LysGlu: 3.924 ± 0.867
2.854LysPhe: 2.854 ± 0.793
2.14LysGly: 2.14 ± 0.67
1.783LysHis: 1.783 ± 0.681
6.956LysIle: 6.956 ± 1.29
4.994LysLys: 4.994 ± 0.65
6.599LysLeu: 6.599 ± 1.002
2.497LysMet: 2.497 ± 0.733
4.102LysAsn: 4.102 ± 0.596
1.427LysPro: 1.427 ± 0.359
1.962LysGln: 1.962 ± 0.589
2.854LysArg: 2.854 ± 0.972
5.529LysSer: 5.529 ± 1.383
5.529LysThr: 5.529 ± 1.147
3.389LysVal: 3.389 ± 0.723
1.07LysTrp: 1.07 ± 0.354
2.675LysTyr: 2.675 ± 0.656
0.0LysXaa: 0.0 ± 0.0
Leu
4.459LeuAla: 4.459 ± 0.608
1.248LeuCys: 1.248 ± 0.666
3.567LeuAsp: 3.567 ± 1.195
5.172LeuGlu: 5.172 ± 0.887
4.28LeuPhe: 4.28 ± 1.176
2.319LeuGly: 2.319 ± 0.623
1.427LeuHis: 1.427 ± 0.42
7.312LeuIle: 7.312 ± 0.954
5.35LeuLys: 5.35 ± 0.835
5.707LeuLeu: 5.707 ± 0.969
2.675LeuMet: 2.675 ± 0.601
6.777LeuAsn: 6.777 ± 1.25
2.497LeuPro: 2.497 ± 0.485
2.319LeuGln: 2.319 ± 0.816
4.994LeuArg: 4.994 ± 0.794
6.777LeuSer: 6.777 ± 0.897
4.994LeuThr: 4.994 ± 1.414
3.567LeuVal: 3.567 ± 1.116
0.892LeuTrp: 0.892 ± 0.386
4.28LeuTyr: 4.28 ± 1.134
0.0LeuXaa: 0.0 ± 0.0
Met
2.319MetAla: 2.319 ± 0.698
0.0MetCys: 0.0 ± 0.0
1.427MetAsp: 1.427 ± 0.47
0.535MetGlu: 0.535 ± 0.235
1.783MetPhe: 1.783 ± 0.527
0.535MetGly: 0.535 ± 0.371
0.713MetHis: 0.713 ± 0.337
1.962MetIle: 1.962 ± 0.563
3.389MetLys: 3.389 ± 0.771
3.21MetLeu: 3.21 ± 0.816
1.427MetMet: 1.427 ± 0.354
3.032MetAsn: 3.032 ± 0.567
1.248MetPro: 1.248 ± 0.462
1.07MetGln: 1.07 ± 0.395
1.248MetArg: 1.248 ± 0.722
2.14MetSer: 2.14 ± 0.475
2.14MetThr: 2.14 ± 0.556
1.783MetVal: 1.783 ± 0.497
0.0MetTrp: 0.0 ± 0.0
1.605MetTyr: 1.605 ± 0.3
0.0MetXaa: 0.0 ± 0.0
Asn
3.924AsnAla: 3.924 ± 0.621
1.07AsnCys: 1.07 ± 0.576
3.389AsnAsp: 3.389 ± 1.003
4.815AsnGlu: 4.815 ± 1.349
2.854AsnPhe: 2.854 ± 0.808
3.745AsnGly: 3.745 ± 1.022
0.892AsnHis: 0.892 ± 0.328
5.35AsnIle: 5.35 ± 1.029
4.459AsnLys: 4.459 ± 0.888
4.459AsnLeu: 4.459 ± 0.821
1.962AsnMet: 1.962 ± 0.426
5.707AsnAsn: 5.707 ± 0.904
2.675AsnPro: 2.675 ± 0.968
2.854AsnGln: 2.854 ± 0.41
2.854AsnArg: 2.854 ± 0.717
7.669AsnSer: 7.669 ± 0.925
5.529AsnThr: 5.529 ± 0.884
6.242AsnVal: 6.242 ± 1.067
0.892AsnTrp: 0.892 ± 0.503
4.815AsnTyr: 4.815 ± 0.517
0.0AsnXaa: 0.0 ± 0.0
Pro
1.962ProAla: 1.962 ± 0.549
0.357ProCys: 0.357 ± 0.374
2.497ProAsp: 2.497 ± 0.344
0.713ProGlu: 0.713 ± 0.331
0.713ProPhe: 0.713 ± 0.36
1.605ProGly: 1.605 ± 0.361
0.178ProHis: 0.178 ± 0.155
3.389ProIle: 3.389 ± 0.565
1.07ProLys: 1.07 ± 0.409
2.675ProLeu: 2.675 ± 0.66
0.892ProMet: 0.892 ± 0.419
1.605ProAsn: 1.605 ± 0.564
1.07ProPro: 1.07 ± 0.456
1.605ProGln: 1.605 ± 0.928
0.713ProArg: 0.713 ± 0.276
1.605ProSer: 1.605 ± 0.433
2.14ProThr: 2.14 ± 0.673
1.605ProVal: 1.605 ± 0.541
0.357ProTrp: 0.357 ± 0.233
2.14ProTyr: 2.14 ± 0.491
0.0ProXaa: 0.0 ± 0.0
Gln
1.962GlnAla: 1.962 ± 0.558
0.535GlnCys: 0.535 ± 0.355
0.892GlnAsp: 0.892 ± 0.303
1.07GlnGlu: 1.07 ± 0.324
2.319GlnPhe: 2.319 ± 0.539
0.713GlnGly: 0.713 ± 0.472
0.535GlnHis: 0.535 ± 0.264
2.319GlnIle: 2.319 ± 0.862
1.605GlnLys: 1.605 ± 0.39
5.172GlnLeu: 5.172 ± 0.808
1.783GlnMet: 1.783 ± 0.693
1.427GlnAsn: 1.427 ± 0.563
1.427GlnPro: 1.427 ± 0.562
1.962GlnGln: 1.962 ± 0.743
1.427GlnArg: 1.427 ± 0.54
2.14GlnSer: 2.14 ± 0.804
2.675GlnThr: 2.675 ± 0.861
1.248GlnVal: 1.248 ± 0.319
0.535GlnTrp: 0.535 ± 0.184
2.319GlnTyr: 2.319 ± 0.564
0.0GlnXaa: 0.0 ± 0.0
Arg
1.962ArgAla: 1.962 ± 0.459
0.713ArgCys: 0.713 ± 0.276
2.675ArgAsp: 2.675 ± 0.618
3.032ArgGlu: 3.032 ± 0.617
3.032ArgPhe: 3.032 ± 0.478
1.427ArgGly: 1.427 ± 0.769
1.248ArgHis: 1.248 ± 0.6
3.924ArgIle: 3.924 ± 0.93
2.14ArgLys: 2.14 ± 0.578
4.28ArgLeu: 4.28 ± 0.501
1.427ArgMet: 1.427 ± 0.513
3.567ArgAsn: 3.567 ± 0.728
0.535ArgPro: 0.535 ± 0.371
1.248ArgGln: 1.248 ± 0.544
3.745ArgArg: 3.745 ± 0.911
3.389ArgSer: 3.389 ± 0.671
2.14ArgThr: 2.14 ± 0.707
1.783ArgVal: 1.783 ± 0.54
0.535ArgTrp: 0.535 ± 0.418
2.14ArgTyr: 2.14 ± 0.669
0.0ArgXaa: 0.0 ± 0.0
Ser
4.459SerAla: 4.459 ± 0.566
1.07SerCys: 1.07 ± 0.296
5.529SerAsp: 5.529 ± 1.265
5.172SerGlu: 5.172 ± 1.052
3.389SerPhe: 3.389 ± 0.693
3.389SerGly: 3.389 ± 1.05
1.783SerHis: 1.783 ± 0.596
4.994SerIle: 4.994 ± 1.422
5.886SerLys: 5.886 ± 0.846
6.064SerLeu: 6.064 ± 1.196
1.427SerMet: 1.427 ± 0.475
7.491SerAsn: 7.491 ± 0.903
2.14SerPro: 2.14 ± 0.681
3.389SerGln: 3.389 ± 0.554
2.854SerArg: 2.854 ± 0.604
6.421SerSer: 6.421 ± 1.038
4.102SerThr: 4.102 ± 0.809
5.35SerVal: 5.35 ± 0.953
0.178SerTrp: 0.178 ± 0.18
4.994SerTyr: 4.994 ± 0.802
0.0SerXaa: 0.0 ± 0.0
Thr
2.854ThrAla: 2.854 ± 0.602
1.248ThrCys: 1.248 ± 0.437
3.745ThrAsp: 3.745 ± 0.981
5.172ThrGlu: 5.172 ± 1.449
3.032ThrPhe: 3.032 ± 0.764
1.962ThrGly: 1.962 ± 0.42
0.713ThrHis: 0.713 ± 0.262
7.312ThrIle: 7.312 ± 1.125
2.854ThrLys: 2.854 ± 0.659
4.459ThrLeu: 4.459 ± 0.973
1.427ThrMet: 1.427 ± 0.489
5.529ThrAsn: 5.529 ± 1.187
2.497ThrPro: 2.497 ± 0.669
2.319ThrGln: 2.319 ± 0.577
2.497ThrArg: 2.497 ± 0.646
4.28ThrSer: 4.28 ± 0.673
5.35ThrThr: 5.35 ± 1.145
4.994ThrVal: 4.994 ± 1.05
0.713ThrTrp: 0.713 ± 0.38
4.637ThrTyr: 4.637 ± 0.964
0.0ThrXaa: 0.0 ± 0.0
Val
3.745ValAla: 3.745 ± 0.998
1.248ValCys: 1.248 ± 0.754
4.102ValAsp: 4.102 ± 0.837
3.389ValGlu: 3.389 ± 1.123
1.962ValPhe: 1.962 ± 0.499
2.675ValGly: 2.675 ± 0.493
1.07ValHis: 1.07 ± 0.301
3.032ValIle: 3.032 ± 0.505
4.815ValLys: 4.815 ± 0.701
4.102ValLeu: 4.102 ± 0.823
1.605ValMet: 1.605 ± 0.491
3.032ValAsn: 3.032 ± 0.717
1.427ValPro: 1.427 ± 0.379
1.962ValGln: 1.962 ± 0.787
3.389ValArg: 3.389 ± 0.849
4.815ValSer: 4.815 ± 0.692
3.567ValThr: 3.567 ± 0.525
3.924ValVal: 3.924 ± 0.806
0.357ValTrp: 0.357 ± 0.296
3.389ValTyr: 3.389 ± 0.599
0.0ValXaa: 0.0 ± 0.0
Trp
0.178TrpAla: 0.178 ± 0.216
0.178TrpCys: 0.178 ± 0.18
0.535TrpAsp: 0.535 ± 0.183
0.713TrpGlu: 0.713 ± 0.286
0.535TrpPhe: 0.535 ± 0.224
0.357TrpGly: 0.357 ± 0.31
0.0TrpHis: 0.0 ± 0.0
1.427TrpIle: 1.427 ± 0.628
0.535TrpLys: 0.535 ± 0.323
1.07TrpLeu: 1.07 ± 0.487
0.357TrpMet: 0.357 ± 0.316
1.605TrpAsn: 1.605 ± 0.532
0.0TrpPro: 0.0 ± 0.0
0.357TrpGln: 0.357 ± 0.218
1.07TrpArg: 1.07 ± 0.363
0.357TrpSer: 0.357 ± 0.249
0.357TrpThr: 0.357 ± 0.279
0.0TrpVal: 0.0 ± 0.0
0.357TrpTrp: 0.357 ± 0.29
0.892TrpTyr: 0.892 ± 0.343
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.497TyrAla: 2.497 ± 0.893
0.535TyrCys: 0.535 ± 0.387
3.389TyrAsp: 3.389 ± 0.668
2.319TyrGlu: 2.319 ± 0.756
3.032TyrPhe: 3.032 ± 0.53
2.14TyrGly: 2.14 ± 0.843
0.892TyrHis: 0.892 ± 0.296
4.28TyrIle: 4.28 ± 0.725
3.389TyrLys: 3.389 ± 1.1
3.032TyrLeu: 3.032 ± 0.765
1.427TyrMet: 1.427 ± 0.348
3.567TyrAsn: 3.567 ± 0.778
1.427TyrPro: 1.427 ± 0.485
1.783TyrGln: 1.783 ± 0.421
2.497TyrArg: 2.497 ± 0.502
4.994TyrSer: 4.994 ± 1.349
5.172TyrThr: 5.172 ± 0.801
3.032TyrVal: 3.032 ± 0.617
0.892TyrTrp: 0.892 ± 0.426
2.497TyrTyr: 2.497 ± 0.551
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (5608 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski