Amino acid dipepetide frequency for Fowl aviadenovirus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.246AlaAla: 8.246 ± 1.502
1.118AlaCys: 1.118 ± 0.681
5.031AlaAsp: 5.031 ± 0.913
6.01AlaGlu: 6.01 ± 0.976
2.795AlaPhe: 2.795 ± 0.485
4.752AlaGly: 4.752 ± 1.062
0.978AlaHis: 0.978 ± 0.331
4.472AlaIle: 4.472 ± 0.93
3.354AlaLys: 3.354 ± 0.573
7.827AlaLeu: 7.827 ± 1.339
2.236AlaMet: 2.236 ± 1.11
3.634AlaAsn: 3.634 ± 0.599
6.01AlaPro: 6.01 ± 1.12
3.634AlaGln: 3.634 ± 0.772
4.193AlaArg: 4.193 ± 0.69
5.451AlaSer: 5.451 ± 1.0
5.451AlaThr: 5.451 ± 1.013
6.569AlaVal: 6.569 ± 1.135
0.839AlaTrp: 0.839 ± 0.315
3.634AlaTyr: 3.634 ± 0.541
0.0AlaXaa: 0.0 ± 0.0
Cys
0.559CysAla: 0.559 ± 0.253
0.14CysCys: 0.14 ± 0.135
1.398CysAsp: 1.398 ± 0.521
0.14CysGlu: 0.14 ± 0.122
0.559CysPhe: 0.559 ± 0.232
0.978CysGly: 0.978 ± 0.502
0.419CysHis: 0.419 ± 0.216
0.419CysIle: 0.419 ± 0.193
0.699CysLys: 0.699 ± 0.331
0.699CysLeu: 0.699 ± 0.262
0.28CysMet: 0.28 ± 0.172
0.839CysAsn: 0.839 ± 0.41
1.258CysPro: 1.258 ± 0.474
0.839CysGln: 0.839 ± 0.292
0.699CysArg: 0.699 ± 0.246
1.258CysSer: 1.258 ± 0.261
0.559CysThr: 0.559 ± 0.324
0.559CysVal: 0.559 ± 0.409
0.28CysTrp: 0.28 ± 0.164
0.559CysTyr: 0.559 ± 0.265
0.0CysXaa: 0.0 ± 0.0
Asp
4.472AspAla: 4.472 ± 0.699
0.559AspCys: 0.559 ± 0.276
4.053AspAsp: 4.053 ± 0.69
4.472AspGlu: 4.472 ± 0.991
2.236AspPhe: 2.236 ± 0.31
3.774AspGly: 3.774 ± 0.681
1.817AspHis: 1.817 ± 0.517
2.795AspIle: 2.795 ± 0.729
2.516AspLys: 2.516 ± 0.729
5.171AspLeu: 5.171 ± 0.86
1.118AspMet: 1.118 ± 0.374
1.398AspAsn: 1.398 ± 0.555
5.311AspPro: 5.311 ± 0.819
1.677AspGln: 1.677 ± 0.579
4.053AspArg: 4.053 ± 0.853
5.311AspSer: 5.311 ± 0.596
3.634AspThr: 3.634 ± 0.777
3.494AspVal: 3.494 ± 0.933
0.419AspTrp: 0.419 ± 0.198
1.817AspTyr: 1.817 ± 0.516
0.0AspXaa: 0.0 ± 0.0
Glu
5.171GluAla: 5.171 ± 0.945
0.419GluCys: 0.419 ± 0.173
3.774GluAsp: 3.774 ± 0.762
9.504GluGlu: 9.504 ± 3.038
1.537GluPhe: 1.537 ± 0.429
3.774GluGly: 3.774 ± 0.464
1.537GluHis: 1.537 ± 0.471
2.516GluIle: 2.516 ± 0.472
1.817GluLys: 1.817 ± 0.633
6.15GluLeu: 6.15 ± 0.858
1.258GluMet: 1.258 ± 0.457
4.053GluAsn: 4.053 ± 0.661
2.795GluPro: 2.795 ± 0.671
2.376GluGln: 2.376 ± 0.667
3.634GluArg: 3.634 ± 0.957
4.472GluSer: 4.472 ± 1.126
3.913GluThr: 3.913 ± 0.758
3.215GluVal: 3.215 ± 0.792
0.559GluTrp: 0.559 ± 0.222
1.118GluTyr: 1.118 ± 0.387
0.0GluXaa: 0.0 ± 0.0
Phe
3.913PheAla: 3.913 ± 0.752
0.14PheCys: 0.14 ± 0.128
3.075PheAsp: 3.075 ± 0.77
2.096PheGlu: 2.096 ± 0.526
1.677PhePhe: 1.677 ± 0.336
1.118PheGly: 1.118 ± 0.349
1.398PheHis: 1.398 ± 0.392
1.118PheIle: 1.118 ± 0.439
2.376PheLys: 2.376 ± 0.315
4.053PheLeu: 4.053 ± 0.809
1.398PheMet: 1.398 ± 0.398
2.516PheAsn: 2.516 ± 0.635
1.677PhePro: 1.677 ± 0.474
1.118PheGln: 1.118 ± 0.435
3.215PheArg: 3.215 ± 0.602
2.096PheSer: 2.096 ± 0.567
2.795PheThr: 2.795 ± 0.505
3.075PheVal: 3.075 ± 0.615
0.839PheTrp: 0.839 ± 0.337
1.817PheTyr: 1.817 ± 0.401
0.0PheXaa: 0.0 ± 0.0
Gly
7.407GlyAla: 7.407 ± 1.387
0.559GlyCys: 0.559 ± 0.204
2.935GlyAsp: 2.935 ± 0.84
3.634GlyGlu: 3.634 ± 1.275
2.795GlyPhe: 2.795 ± 0.514
6.01GlyGly: 6.01 ± 1.529
0.978GlyHis: 0.978 ± 0.41
2.376GlyIle: 2.376 ± 0.941
1.817GlyLys: 1.817 ± 0.595
3.354GlyLeu: 3.354 ± 1.041
1.398GlyMet: 1.398 ± 0.385
3.075GlyAsn: 3.075 ± 0.856
3.494GlyPro: 3.494 ± 1.025
1.677GlyGln: 1.677 ± 0.52
4.193GlyArg: 4.193 ± 0.773
3.634GlySer: 3.634 ± 0.728
3.634GlyThr: 3.634 ± 0.795
5.031GlyVal: 5.031 ± 1.258
1.118GlyTrp: 1.118 ± 0.214
2.655GlyTyr: 2.655 ± 0.606
0.0GlyXaa: 0.0 ± 0.0
His
1.118HisAla: 1.118 ± 0.349
0.14HisCys: 0.14 ± 0.122
1.258HisAsp: 1.258 ± 0.478
0.978HisGlu: 0.978 ± 0.354
0.559HisPhe: 0.559 ± 0.265
1.537HisGly: 1.537 ± 0.524
1.118HisHis: 1.118 ± 0.404
1.118HisIle: 1.118 ± 0.379
0.14HisLys: 0.14 ± 0.135
1.957HisLeu: 1.957 ± 0.688
0.14HisMet: 0.14 ± 0.131
1.677HisAsn: 1.677 ± 0.323
1.957HisPro: 1.957 ± 0.526
1.118HisGln: 1.118 ± 0.567
1.957HisArg: 1.957 ± 0.564
0.978HisSer: 0.978 ± 0.3
1.118HisThr: 1.118 ± 0.435
2.096HisVal: 2.096 ± 0.616
0.14HisTrp: 0.14 ± 0.122
0.839HisTyr: 0.839 ± 0.27
0.0HisXaa: 0.0 ± 0.0
Ile
3.494IleAla: 3.494 ± 0.869
0.839IleCys: 0.839 ± 0.416
2.376IleAsp: 2.376 ± 0.524
1.957IleGlu: 1.957 ± 0.42
1.258IlePhe: 1.258 ± 0.465
2.516IleGly: 2.516 ± 0.461
0.419IleHis: 0.419 ± 0.197
0.699IleIle: 0.699 ± 0.314
1.398IleLys: 1.398 ± 0.502
2.935IleLeu: 2.935 ± 0.607
0.14IleMet: 0.14 ± 0.128
2.236IleAsn: 2.236 ± 0.903
3.494IlePro: 3.494 ± 0.648
1.817IleGln: 1.817 ± 0.591
2.795IleArg: 2.795 ± 0.561
2.236IleSer: 2.236 ± 0.366
2.236IleThr: 2.236 ± 0.587
2.236IleVal: 2.236 ± 0.518
0.28IleTrp: 0.28 ± 0.179
1.677IleTyr: 1.677 ± 0.39
0.0IleXaa: 0.0 ± 0.0
Lys
3.354LysAla: 3.354 ± 1.05
0.419LysCys: 0.419 ± 0.184
1.677LysAsp: 1.677 ± 0.38
2.376LysGlu: 2.376 ± 0.755
2.096LysPhe: 2.096 ± 0.529
1.957LysGly: 1.957 ± 0.525
0.419LysHis: 0.419 ± 0.168
1.398LysIle: 1.398 ± 0.387
2.516LysLys: 2.516 ± 0.87
3.634LysLeu: 3.634 ± 0.779
1.118LysMet: 1.118 ± 0.417
2.236LysAsn: 2.236 ± 0.52
1.677LysPro: 1.677 ± 0.492
0.978LysGln: 0.978 ± 0.352
3.774LysArg: 3.774 ± 0.823
1.537LysSer: 1.537 ± 0.633
2.935LysThr: 2.935 ± 0.733
1.677LysVal: 1.677 ± 0.456
0.28LysTrp: 0.28 ± 0.179
2.096LysTyr: 2.096 ± 0.781
0.0LysXaa: 0.0 ± 0.0
Leu
6.569LeuAla: 6.569 ± 0.647
0.839LeuCys: 0.839 ± 0.224
4.892LeuAsp: 4.892 ± 0.552
4.472LeuGlu: 4.472 ± 0.47
3.913LeuPhe: 3.913 ± 0.749
4.333LeuGly: 4.333 ± 0.675
2.096LeuHis: 2.096 ± 0.663
2.795LeuIle: 2.795 ± 0.498
3.494LeuLys: 3.494 ± 0.698
7.128LeuLeu: 7.128 ± 1.017
2.096LeuMet: 2.096 ± 0.627
4.333LeuAsn: 4.333 ± 0.861
3.913LeuPro: 3.913 ± 0.653
4.612LeuGln: 4.612 ± 0.578
5.171LeuArg: 5.171 ± 1.048
6.15LeuSer: 6.15 ± 0.718
6.848LeuThr: 6.848 ± 0.779
3.354LeuVal: 3.354 ± 0.575
1.398LeuTrp: 1.398 ± 0.387
3.075LeuTyr: 3.075 ± 0.832
0.0LeuXaa: 0.0 ± 0.0
Met
2.795MetAla: 2.795 ± 0.686
0.14MetCys: 0.14 ± 0.153
1.677MetAsp: 1.677 ± 0.496
0.419MetGlu: 0.419 ± 0.278
0.699MetPhe: 0.699 ± 0.271
0.978MetGly: 0.978 ± 0.391
0.699MetHis: 0.699 ± 0.358
0.699MetIle: 0.699 ± 0.231
0.839MetLys: 0.839 ± 0.321
1.957MetLeu: 1.957 ± 0.43
0.419MetMet: 0.419 ± 0.273
0.839MetAsn: 0.839 ± 0.274
1.537MetPro: 1.537 ± 0.317
0.839MetGln: 0.839 ± 0.328
2.096MetArg: 2.096 ± 0.508
1.398MetSer: 1.398 ± 0.529
0.978MetThr: 0.978 ± 0.379
1.677MetVal: 1.677 ± 0.543
0.14MetTrp: 0.14 ± 0.131
0.839MetTyr: 0.839 ± 0.304
0.0MetXaa: 0.0 ± 0.0
Asn
3.913AsnAla: 3.913 ± 0.769
0.978AsnCys: 0.978 ± 0.415
2.516AsnAsp: 2.516 ± 0.765
2.795AsnGlu: 2.795 ± 0.738
2.096AsnPhe: 2.096 ± 0.891
3.215AsnGly: 3.215 ± 1.119
0.839AsnHis: 0.839 ± 0.239
1.957AsnIle: 1.957 ± 0.696
1.817AsnLys: 1.817 ± 0.485
3.774AsnLeu: 3.774 ± 0.731
1.118AsnMet: 1.118 ± 0.544
1.537AsnAsn: 1.537 ± 0.436
4.333AsnPro: 4.333 ± 1.027
1.957AsnGln: 1.957 ± 0.543
2.935AsnArg: 2.935 ± 0.75
2.655AsnSer: 2.655 ± 0.848
3.215AsnThr: 3.215 ± 0.713
4.193AsnVal: 4.193 ± 1.037
1.118AsnTrp: 1.118 ± 0.557
2.236AsnTyr: 2.236 ± 0.612
0.0AsnXaa: 0.0 ± 0.0
Pro
6.15ProAla: 6.15 ± 1.681
0.839ProCys: 0.839 ± 0.36
3.774ProAsp: 3.774 ± 0.426
5.031ProGlu: 5.031 ± 0.701
2.655ProPhe: 2.655 ± 0.56
2.516ProGly: 2.516 ± 0.484
1.957ProHis: 1.957 ± 0.515
2.096ProIle: 2.096 ± 0.799
1.817ProLys: 1.817 ± 0.555
3.913ProLeu: 3.913 ± 0.72
0.978ProMet: 0.978 ± 0.631
3.913ProAsn: 3.913 ± 0.956
7.268ProPro: 7.268 ± 1.533
2.376ProGln: 2.376 ± 0.749
3.634ProArg: 3.634 ± 0.842
5.73ProSer: 5.73 ± 0.914
5.171ProThr: 5.171 ± 0.796
4.193ProVal: 4.193 ± 0.928
0.14ProTrp: 0.14 ± 0.122
2.655ProTyr: 2.655 ± 0.758
0.0ProXaa: 0.0 ± 0.0
Gln
3.075GlnAla: 3.075 ± 0.714
0.28GlnCys: 0.28 ± 0.16
1.957GlnAsp: 1.957 ± 0.51
2.376GlnGlu: 2.376 ± 0.743
1.677GlnPhe: 1.677 ± 0.509
2.236GlnGly: 2.236 ± 0.508
1.118GlnHis: 1.118 ± 0.599
1.398GlnIle: 1.398 ± 0.385
1.537GlnLys: 1.537 ± 0.43
3.913GlnLeu: 3.913 ± 0.661
1.118GlnMet: 1.118 ± 0.39
2.655GlnAsn: 2.655 ± 0.882
1.537GlnPro: 1.537 ± 0.412
2.795GlnGln: 2.795 ± 0.938
3.215GlnArg: 3.215 ± 0.781
2.376GlnSer: 2.376 ± 0.68
2.935GlnThr: 2.935 ± 0.789
2.096GlnVal: 2.096 ± 0.492
0.28GlnTrp: 0.28 ± 0.167
1.957GlnTyr: 1.957 ± 0.525
0.0GlnXaa: 0.0 ± 0.0
Arg
4.472ArgAla: 4.472 ± 0.825
0.978ArgCys: 0.978 ± 0.453
3.354ArgAsp: 3.354 ± 0.842
3.634ArgGlu: 3.634 ± 0.915
3.494ArgPhe: 3.494 ± 0.552
4.612ArgGly: 4.612 ± 0.852
2.655ArgHis: 2.655 ± 0.869
2.236ArgIle: 2.236 ± 0.701
3.215ArgLys: 3.215 ± 0.966
4.752ArgLeu: 4.752 ± 0.977
1.537ArgMet: 1.537 ± 0.367
3.774ArgAsn: 3.774 ± 1.23
4.752ArgPro: 4.752 ± 1.046
3.354ArgGln: 3.354 ± 0.625
8.526ArgArg: 8.526 ± 2.465
4.892ArgSer: 4.892 ± 0.865
3.215ArgThr: 3.215 ± 0.536
4.892ArgVal: 4.892 ± 0.908
1.118ArgTrp: 1.118 ± 0.301
2.376ArgTyr: 2.376 ± 0.498
0.0ArgXaa: 0.0 ± 0.0
Ser
4.892SerAla: 4.892 ± 1.051
1.258SerCys: 1.258 ± 0.431
5.59SerAsp: 5.59 ± 1.263
3.913SerGlu: 3.913 ± 0.714
3.075SerPhe: 3.075 ± 0.76
7.966SerGly: 7.966 ± 1.918
0.699SerHis: 0.699 ± 0.296
2.655SerIle: 2.655 ± 0.563
2.935SerLys: 2.935 ± 0.971
4.333SerLeu: 4.333 ± 0.777
1.258SerMet: 1.258 ± 0.357
2.795SerAsn: 2.795 ± 0.813
3.774SerPro: 3.774 ± 1.021
1.957SerGln: 1.957 ± 0.676
4.892SerArg: 4.892 ± 0.673
5.031SerSer: 5.031 ± 1.174
4.333SerThr: 4.333 ± 0.667
2.795SerVal: 2.795 ± 0.503
1.118SerTrp: 1.118 ± 0.39
2.096SerTyr: 2.096 ± 0.514
0.0SerXaa: 0.0 ± 0.0
Thr
7.966ThrAla: 7.966 ± 1.631
1.118ThrCys: 1.118 ± 0.359
2.935ThrAsp: 2.935 ± 0.738
3.774ThrGlu: 3.774 ± 0.683
2.935ThrPhe: 2.935 ± 0.587
3.913ThrGly: 3.913 ± 0.985
0.699ThrHis: 0.699 ± 0.38
2.516ThrIle: 2.516 ± 0.396
0.839ThrLys: 0.839 ± 0.223
4.612ThrLeu: 4.612 ± 1.054
1.118ThrMet: 1.118 ± 0.32
2.795ThrAsn: 2.795 ± 0.716
3.494ThrPro: 3.494 ± 1.019
2.376ThrGln: 2.376 ± 0.563
4.612ThrArg: 4.612 ± 0.946
3.634ThrSer: 3.634 ± 1.0
3.774ThrThr: 3.774 ± 0.875
5.171ThrVal: 5.171 ± 0.702
0.28ThrTrp: 0.28 ± 0.186
3.774ThrTyr: 3.774 ± 0.895
0.0ThrXaa: 0.0 ± 0.0
Val
4.752ValAla: 4.752 ± 1.121
1.398ValCys: 1.398 ± 0.444
4.053ValAsp: 4.053 ± 0.673
3.215ValGlu: 3.215 ± 0.789
2.935ValPhe: 2.935 ± 0.514
3.075ValGly: 3.075 ± 0.584
1.118ValHis: 1.118 ± 0.323
2.935ValIle: 2.935 ± 0.555
2.795ValLys: 2.795 ± 0.961
6.988ValLeu: 6.988 ± 0.69
0.978ValMet: 0.978 ± 0.382
2.376ValAsn: 2.376 ± 0.744
4.892ValPro: 4.892 ± 0.976
3.494ValGln: 3.494 ± 0.797
4.193ValArg: 4.193 ± 0.834
4.612ValSer: 4.612 ± 0.667
3.774ValThr: 3.774 ± 0.549
4.053ValVal: 4.053 ± 0.758
0.559ValTrp: 0.559 ± 0.277
2.516ValTyr: 2.516 ± 0.57
0.0ValXaa: 0.0 ± 0.0
Trp
0.839TrpAla: 0.839 ± 0.345
0.419TrpCys: 0.419 ± 0.228
0.419TrpAsp: 0.419 ± 0.234
0.699TrpGlu: 0.699 ± 0.189
0.0TrpPhe: 0.0 ± 0.0
0.419TrpGly: 0.419 ± 0.178
0.14TrpHis: 0.14 ± 0.135
0.14TrpIle: 0.14 ± 0.122
0.559TrpLys: 0.559 ± 0.352
0.978TrpLeu: 0.978 ± 0.237
0.28TrpMet: 0.28 ± 0.214
0.559TrpAsn: 0.559 ± 0.239
0.699TrpPro: 0.699 ± 0.664
0.839TrpGln: 0.839 ± 0.37
1.118TrpArg: 1.118 ± 0.347
0.839TrpSer: 0.839 ± 0.299
0.699TrpThr: 0.699 ± 0.299
1.258TrpVal: 1.258 ± 0.374
0.0TrpTrp: 0.0 ± 0.0
0.559TrpTyr: 0.559 ± 0.226
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.075TyrAla: 3.075 ± 0.445
0.559TyrCys: 0.559 ± 0.223
3.354TyrAsp: 3.354 ± 1.219
2.096TyrGlu: 2.096 ± 0.528
2.516TyrPhe: 2.516 ± 0.654
2.096TyrGly: 2.096 ± 0.669
0.839TyrHis: 0.839 ± 0.247
0.699TyrIle: 0.699 ± 0.228
1.677TyrLys: 1.677 ± 0.502
3.354TyrLeu: 3.354 ± 0.919
1.537TyrMet: 1.537 ± 0.637
1.957TyrAsn: 1.957 ± 0.597
3.075TyrPro: 3.075 ± 0.498
0.699TyrGln: 0.699 ± 0.286
2.935TyrArg: 2.935 ± 0.62
3.075TyrSer: 3.075 ± 0.8
1.118TyrThr: 1.118 ± 0.404
3.075TyrVal: 3.075 ± 0.451
0.559TyrTrp: 0.559 ± 0.363
0.839TyrTyr: 0.839 ± 0.258
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 14 proteins (7156 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski