Amino acid dipepetide frequency for Gibberella nygamai (Bean root rot disease fungus) (Fusarium nygamai)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.455AlaAla: 8.455 ± 0.052	1.098AlaCys: 1.098 ± 0.013	4.183AlaAsp: 4.183 ± 0.027	5.061AlaGlu: 5.061 ± 0.035	3.17AlaPhe: 3.17 ± 0.028	5.596AlaGly: 5.596 ± 0.036	1.684AlaHis: 1.684 ± 0.015	4.536AlaIle: 4.536 ± 0.027	4.212AlaLys: 4.212 ± 0.031	7.577AlaLeu: 7.577 ± 0.039	1.987AlaMet: 1.987 ± 0.016	2.943AlaAsn: 2.943 ± 0.021	4.582AlaPro: 4.582 ± 0.037	3.298AlaGln: 3.298 ± 0.024	4.547AlaArg: 4.547 ± 0.026	6.964AlaSer: 6.964 ± 0.033	5.217AlaThr: 5.217 ± 0.032	5.292AlaVal: 5.292 ± 0.033	1.231AlaTrp: 1.231 ± 0.016	2.184AlaTyr: 2.184 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.931CysAla: 0.931 ± 0.013	0.247CysCys: 0.247 ± 0.007	0.701CysAsp: 0.701 ± 0.012	0.643CysGlu: 0.643 ± 0.011	0.562CysPhe: 0.562 ± 0.009	0.95CysGly: 0.95 ± 0.015	0.343CysHis: 0.343 ± 0.007	0.756CysIle: 0.756 ± 0.012	0.566CysLys: 0.566 ± 0.01	1.275CysLeu: 1.275 ± 0.015	0.284CysMet: 0.284 ± 0.006	0.464CysAsn: 0.464 ± 0.009	0.668CysPro: 0.668 ± 0.012	0.477CysGln: 0.477 ± 0.009	0.73CysArg: 0.73 ± 0.011	0.906CysSer: 0.906 ± 0.012	0.707CysThr: 0.707 ± 0.012	0.818CysVal: 0.818 ± 0.013	0.225CysTrp: 0.225 ± 0.006	0.384CysTyr: 0.384 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.706AspAla: 4.706 ± 0.027	0.684AspCys: 0.684 ± 0.012	4.517AspAsp: 4.517 ± 0.034	4.67AspGlu: 4.67 ± 0.033	2.335AspPhe: 2.335 ± 0.018	4.153AspGly: 4.153 ± 0.025	1.302AspHis: 1.302 ± 0.014	3.329AspIle: 3.329 ± 0.022	2.808AspLys: 2.808 ± 0.023	5.199AspLeu: 5.199 ± 0.034	1.398AspMet: 1.398 ± 0.013	2.088AspAsn: 2.088 ± 0.019	3.335AspPro: 3.335 ± 0.024	1.979AspGln: 1.979 ± 0.017	2.997AspArg: 2.997 ± 0.028	4.164AspSer: 4.164 ± 0.029	3.128AspThr: 3.128 ± 0.025	3.762AspVal: 3.762 ± 0.026	0.975AspTrp: 0.975 ± 0.011	1.659AspTyr: 1.659 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.601GluAla: 5.601 ± 0.033	0.669GluCys: 0.669 ± 0.01	4.331GluAsp: 4.331 ± 0.032	5.364GluGlu: 5.364 ± 0.043	2.035GluPhe: 2.035 ± 0.016	3.744GluGly: 3.744 ± 0.027	1.446GluHis: 1.446 ± 0.016	3.105GluIle: 3.105 ± 0.021	3.78GluLys: 3.78 ± 0.027	5.258GluLeu: 5.258 ± 0.029	1.504GluMet: 1.504 ± 0.017	2.367GluAsn: 2.367 ± 0.018	2.961GluPro: 2.961 ± 0.028	2.47GluGln: 2.47 ± 0.021	3.746GluArg: 3.746 ± 0.031	4.307GluSer: 4.307 ± 0.027	3.76GluThr: 3.76 ± 0.03	3.647GluVal: 3.647 ± 0.025	0.953GluTrp: 0.953 ± 0.013	1.717GluTyr: 1.717 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.028PheAla: 3.028 ± 0.02	0.581PheCys: 0.581 ± 0.01	2.398PheAsp: 2.398 ± 0.019	2.24PheGlu: 2.24 ± 0.018	1.669PhePhe: 1.669 ± 0.018	2.911PheGly: 2.911 ± 0.025	0.914PheHis: 0.914 ± 0.013	1.995PheIle: 1.995 ± 0.02	1.695PheLys: 1.695 ± 0.018	3.443PheLeu: 3.443 ± 0.025	0.852PheMet: 0.852 ± 0.012	1.533PheAsn: 1.533 ± 0.016	1.907PhePro: 1.907 ± 0.016	1.435PheGln: 1.435 ± 0.016	1.918PheArg: 1.918 ± 0.016	2.962PheSer: 2.962 ± 0.021	2.229PheThr: 2.229 ± 0.015	2.385PheVal: 2.385 ± 0.021	0.683PheTrp: 0.683 ± 0.011	1.146PheTyr: 1.146 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	5.105GlyAla: 5.105 ± 0.032	0.913GlyCys: 0.913 ± 0.013	3.802GlyAsp: 3.802 ± 0.028	3.553GlyGlu: 3.553 ± 0.028	2.875GlyPhe: 2.875 ± 0.022	5.43GlyGly: 5.43 ± 0.048	1.734GlyHis: 1.734 ± 0.016	3.725GlyIle: 3.725 ± 0.025	3.551GlyLys: 3.551 ± 0.032	6.126GlyLeu: 6.126 ± 0.034	1.589GlyMet: 1.589 ± 0.014	2.675GlyAsn: 2.675 ± 0.028	3.263GlyPro: 3.263 ± 0.023	2.569GlyGln: 2.569 ± 0.021	3.912GlyArg: 3.912 ± 0.025	5.669GlySer: 5.669 ± 0.035	3.994GlyThr: 3.994 ± 0.037	4.249GlyVal: 4.249 ± 0.03	1.218GlyTrp: 1.218 ± 0.013	2.214GlyTyr: 2.214 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.71HisAla: 1.71 ± 0.015	0.333HisCys: 0.333 ± 0.006	1.401HisAsp: 1.401 ± 0.012	1.401HisGlu: 1.401 ± 0.015	0.926HisPhe: 0.926 ± 0.012	1.742HisGly: 1.742 ± 0.018	0.842HisHis: 0.842 ± 0.015	1.262HisIle: 1.262 ± 0.013	0.99HisLys: 0.99 ± 0.014	2.218HisLeu: 2.218 ± 0.018	0.529HisMet: 0.529 ± 0.008	0.857HisAsn: 0.857 ± 0.009	1.538HisPro: 1.538 ± 0.014	0.995HisGln: 0.995 ± 0.012	1.476HisArg: 1.476 ± 0.016	1.721HisSer: 1.721 ± 0.017	1.193HisThr: 1.193 ± 0.013	1.426HisVal: 1.426 ± 0.014	0.364HisTrp: 0.364 ± 0.006	0.721HisTyr: 0.721 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.326IleAla: 4.326 ± 0.026	0.788IleCys: 0.788 ± 0.012	3.102IleAsp: 3.102 ± 0.023	3.112IleGlu: 3.112 ± 0.022	2.07IlePhe: 2.07 ± 0.019	3.376IleGly: 3.376 ± 0.025	1.242IleHis: 1.242 ± 0.014	2.757IleIle: 2.757 ± 0.024	2.425IleLys: 2.425 ± 0.018	4.66IleLeu: 4.66 ± 0.031	1.104IleMet: 1.104 ± 0.013	1.976IleAsn: 1.976 ± 0.018	3.085IlePro: 3.085 ± 0.021	1.997IleGln: 1.997 ± 0.018	2.829IleArg: 2.829 ± 0.022	3.946IleSer: 3.946 ± 0.023	2.997IleThr: 2.997 ± 0.025	3.313IleVal: 3.313 ± 0.027	0.799IleTrp: 0.799 ± 0.01	1.464IleTyr: 1.464 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.487LysAla: 4.487 ± 0.03	0.54LysCys: 0.54 ± 0.011	3.174LysAsp: 3.174 ± 0.023	3.505LysGlu: 3.505 ± 0.027	1.581LysPhe: 1.581 ± 0.015	3.143LysGly: 3.143 ± 0.023	1.199LysHis: 1.199 ± 0.014	2.383LysIle: 2.383 ± 0.022	3.443LysLys: 3.443 ± 0.037	4.305LysLeu: 4.305 ± 0.028	1.066LysMet: 1.066 ± 0.014	1.915LysAsn: 1.915 ± 0.02	2.917LysPro: 2.917 ± 0.03	1.915LysGln: 1.915 ± 0.018	3.332LysArg: 3.332 ± 0.027	3.612LysSer: 3.612 ± 0.029	3.101LysThr: 3.101 ± 0.025	2.97LysVal: 2.97 ± 0.021	0.77LysTrp: 0.77 ± 0.01	1.472LysTyr: 1.472 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	7.673LeuAla: 7.673 ± 0.039	1.214LeuCys: 1.214 ± 0.013	5.278LeuAsp: 5.278 ± 0.034	5.629LeuGlu: 5.629 ± 0.036	3.348LeuPhe: 3.348 ± 0.024	5.925LeuGly: 5.925 ± 0.032	2.132LeuHis: 2.132 ± 0.019	4.151LeuIle: 4.151 ± 0.026	4.383LeuLys: 4.383 ± 0.029	8.012LeuLeu: 8.012 ± 0.049	1.864LeuMet: 1.864 ± 0.016	3.215LeuAsn: 3.215 ± 0.021	5.211LeuPro: 5.211 ± 0.027	3.748LeuGln: 3.748 ± 0.03	5.457LeuArg: 5.457 ± 0.035	7.07LeuSer: 7.07 ± 0.04	4.788LeuThr: 4.788 ± 0.024	5.43LeuVal: 5.43 ± 0.03	1.268LeuTrp: 1.268 ± 0.015	2.347LeuTyr: 2.347 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.298MetAla: 2.298 ± 0.018	0.255MetCys: 0.255 ± 0.006	1.308MetAsp: 1.308 ± 0.015	1.308MetGlu: 1.308 ± 0.013	0.788MetPhe: 0.788 ± 0.011	1.505MetGly: 1.505 ± 0.016	0.486MetHis: 0.486 ± 0.009	1.084MetIle: 1.084 ± 0.012	1.103MetLys: 1.103 ± 0.013	1.884MetLeu: 1.884 ± 0.019	0.638MetMet: 0.638 ± 0.01	0.838MetAsn: 0.838 ± 0.012	1.322MetPro: 1.322 ± 0.016	0.847MetGln: 0.847 ± 0.011	1.244MetArg: 1.244 ± 0.013	1.974MetSer: 1.974 ± 0.017	1.362MetThr: 1.362 ± 0.013	1.346MetVal: 1.346 ± 0.014	0.275MetTrp: 0.275 ± 0.007	0.54MetTyr: 0.54 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.095AsnAla: 3.095 ± 0.023	0.484AsnCys: 0.484 ± 0.009	2.127AsnAsp: 2.127 ± 0.018	2.123AsnGlu: 2.123 ± 0.015	1.418AsnPhe: 1.418 ± 0.013	3.042AsnGly: 3.042 ± 0.027	0.869AsnHis: 0.869 ± 0.012	2.138AsnIle: 2.138 ± 0.018	1.79AsnLys: 1.79 ± 0.016	3.338AsnLeu: 3.338 ± 0.021	0.929AsnMet: 0.929 ± 0.012	1.611AsnAsn: 1.611 ± 0.019	2.419AsnPro: 2.419 ± 0.021	1.391AsnGln: 1.391 ± 0.015	1.948AsnArg: 1.948 ± 0.015	2.788AsnSer: 2.788 ± 0.021	2.283AsnThr: 2.283 ± 0.021	2.304AsnVal: 2.304 ± 0.018	0.636AsnTrp: 0.636 ± 0.009	1.075AsnTyr: 1.075 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.79ProAla: 4.79 ± 0.034	0.526ProCys: 0.526 ± 0.009	3.312ProAsp: 3.312 ± 0.024	4.02ProGlu: 4.02 ± 0.026	2.067ProPhe: 2.067 ± 0.018	3.928ProGly: 3.928 ± 0.035	1.253ProHis: 1.253 ± 0.014	2.553ProIle: 2.553 ± 0.022	2.819ProLys: 2.819 ± 0.022	4.508ProLeu: 4.508 ± 0.029	1.108ProMet: 1.108 ± 0.013	2.23ProAsn: 2.23 ± 0.019	4.542ProPro: 4.542 ± 0.058	2.437ProGln: 2.437 ± 0.023	3.181ProArg: 3.181 ± 0.027	5.504ProSer: 5.504 ± 0.036	3.774ProThr: 3.774 ± 0.029	3.578ProVal: 3.578 ± 0.025	0.801ProTrp: 0.801 ± 0.01	1.503ProTyr: 1.503 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.472GlnAla: 3.472 ± 0.028	0.436GlnCys: 0.436 ± 0.008	2.297GlnAsp: 2.297 ± 0.021	2.482GlnGlu: 2.482 ± 0.024	1.298GlnPhe: 1.298 ± 0.014	2.515GlnGly: 2.515 ± 0.022	1.045GlnHis: 1.045 ± 0.014	1.871GlnIle: 1.871 ± 0.017	1.994GlnLys: 1.994 ± 0.021	3.387GlnLeu: 3.387 ± 0.024	0.893GlnMet: 0.893 ± 0.013	1.558GlnAsn: 1.558 ± 0.017	2.516GlnPro: 2.516 ± 0.026	2.357GlnGln: 2.357 ± 0.038	2.497GlnArg: 2.497 ± 0.023	2.973GlnSer: 2.973 ± 0.022	2.297GlnThr: 2.297 ± 0.02	2.258GlnVal: 2.258 ± 0.018	0.617GlnTrp: 0.617 ± 0.009	1.149GlnTyr: 1.149 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.342ArgAla: 4.342 ± 0.024	0.697ArgCys: 0.697 ± 0.01	3.43ArgAsp: 3.43 ± 0.032	3.629ArgGlu: 3.629 ± 0.031	2.132ArgPhe: 2.132 ± 0.015	3.518ArgGly: 3.518 ± 0.03	1.511ArgHis: 1.511 ± 0.015	2.851ArgIle: 2.851 ± 0.021	3.273ArgLys: 3.273 ± 0.023	5.306ArgLeu: 5.306 ± 0.032	1.298ArgMet: 1.298 ± 0.013	2.225ArgAsn: 2.225 ± 0.02	3.297ArgPro: 3.297 ± 0.027	2.499ArgGln: 2.499 ± 0.023	4.716ArgArg: 4.716 ± 0.04	4.407ArgSer: 4.407 ± 0.035	3.078ArgThr: 3.078 ± 0.024	3.257ArgVal: 3.257 ± 0.024	0.944ArgTrp: 0.944 ± 0.012	1.686ArgTyr: 1.686 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.175SerAla: 6.175 ± 0.034	0.906SerCys: 0.906 ± 0.014	4.412SerAsp: 4.412 ± 0.025	4.246SerGlu: 4.246 ± 0.027	3.054SerPhe: 3.054 ± 0.022	5.428SerGly: 5.428 ± 0.034	1.891SerHis: 1.891 ± 0.021	4.122SerIle: 4.122 ± 0.029	3.851SerLys: 3.851 ± 0.025	6.963SerLeu: 6.963 ± 0.041	1.748SerMet: 1.748 ± 0.017	2.991SerAsn: 2.991 ± 0.021	5.056SerPro: 5.056 ± 0.039	3.26SerGln: 3.26 ± 0.028	4.69SerArg: 4.69 ± 0.038	8.032SerSer: 8.032 ± 0.061	5.259SerThr: 5.259 ± 0.042	4.514SerVal: 4.514 ± 0.026	1.204SerTrp: 1.204 ± 0.012	2.12SerTyr: 2.12 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.106ThrAla: 5.106 ± 0.036	0.776ThrCys: 0.776 ± 0.013	2.947ThrAsp: 2.947 ± 0.023	3.359ThrGlu: 3.359 ± 0.026	2.258ThrPhe: 2.258 ± 0.02	4.201ThrGly: 4.201 ± 0.036	1.22ThrHis: 1.22 ± 0.014	3.274ThrIle: 3.274 ± 0.033	2.908ThrLys: 2.908 ± 0.023	5.11ThrLeu: 5.11 ± 0.03	1.214ThrMet: 1.214 ± 0.013	2.176ThrAsn: 2.176 ± 0.019	4.134ThrPro: 4.134 ± 0.03	2.145ThrGln: 2.145 ± 0.02	3.065ThrArg: 3.065 ± 0.022	5.177ThrSer: 5.177 ± 0.04	4.358ThrThr: 4.358 ± 0.058	3.812ThrVal: 3.812 ± 0.037	0.939ThrTrp: 0.939 ± 0.012	1.658ThrTyr: 1.658 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	5.139ValAla: 5.139 ± 0.032	0.845ValCys: 0.845 ± 0.014	3.781ValAsp: 3.781 ± 0.027	3.921ValGlu: 3.921 ± 0.024	2.523ValPhe: 2.523 ± 0.023	3.924ValGly: 3.924 ± 0.031	1.36ValHis: 1.36 ± 0.014	3.172ValIle: 3.172 ± 0.023	3.114ValLys: 3.114 ± 0.023	5.469ValLeu: 5.469 ± 0.03	1.363ValMet: 1.363 ± 0.013	2.289ValAsn: 2.289 ± 0.017	3.541ValPro: 3.541 ± 0.027	2.36ValGln: 2.36 ± 0.018	3.239ValArg: 3.239 ± 0.022	4.61ValSer: 4.61 ± 0.026	3.672ValThr: 3.672 ± 0.035	4.277ValVal: 4.277 ± 0.033	0.893ValTrp: 0.893 ± 0.011	1.767ValTyr: 1.767 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.228TrpAla: 1.228 ± 0.015	0.208TrpCys: 0.208 ± 0.006	0.968TrpAsp: 0.968 ± 0.013	0.891TrpGlu: 0.891 ± 0.012	0.604TrpPhe: 0.604 ± 0.008	1.0TrpGly: 1.0 ± 0.013	0.385TrpHis: 0.385 ± 0.008	0.862TrpIle: 0.862 ± 0.013	0.893TrpLys: 0.893 ± 0.012	1.47TrpLeu: 1.47 ± 0.016	0.396TrpMet: 0.396 ± 0.007	0.675TrpAsn: 0.675 ± 0.01	0.657TrpPro: 0.657 ± 0.01	0.606TrpGln: 0.606 ± 0.01	0.936TrpArg: 0.936 ± 0.01	1.105TrpSer: 1.105 ± 0.013	0.985TrpThr: 0.985 ± 0.011	0.951TrpVal: 0.951 ± 0.012	0.305TrpTrp: 0.305 ± 0.006	0.476TrpTyr: 0.476 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.149TyrAla: 2.149 ± 0.019	0.437TyrCys: 0.437 ± 0.007	1.72TyrAsp: 1.72 ± 0.016	1.606TyrGlu: 1.606 ± 0.017	1.21TyrPhe: 1.21 ± 0.013	2.135TyrGly: 2.135 ± 0.021	0.788TyrHis: 0.788 ± 0.012	1.441TyrIle: 1.441 ± 0.014	1.232TyrLys: 1.232 ± 0.016	2.634TyrLeu: 2.634 ± 0.021	0.642TyrMet: 0.642 ± 0.01	1.184TyrAsn: 1.184 ± 0.015	1.48TyrPro: 1.48 ± 0.017	1.126TyrGln: 1.126 ± 0.012	1.638TyrArg: 1.638 ± 0.015	2.032TyrSer: 2.032 ± 0.018	1.659TyrThr: 1.659 ± 0.022	1.668TyrVal: 1.668 ± 0.014	0.502TyrTrp: 0.502 ± 0.008	0.953TyrTyr: 0.953 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16018 proteins (7249913 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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