Amino acid dipepetide frequency for Tomato bushy stunt virus (strain Cherry) (TBSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.109AlaAla: 5.109 ± 1.032
0.0AlaCys: 0.0 ± 0.0
1.277AlaAsp: 1.277 ± 0.51
1.277AlaGlu: 1.277 ± 0.51
2.554AlaPhe: 2.554 ± 0.959
5.109AlaGly: 5.109 ± 1.757
2.554AlaHis: 2.554 ± 1.519
5.747AlaIle: 5.747 ± 2.051
3.831AlaLys: 3.831 ± 2.278
6.386AlaLeu: 6.386 ± 1.466
3.193AlaMet: 3.193 ± 1.297
1.916AlaAsn: 1.916 ± 0.854
3.193AlaPro: 3.193 ± 0.915
1.277AlaGln: 1.277 ± 0.759
3.831AlaArg: 3.831 ± 1.595
5.747AlaSer: 5.747 ± 1.242
7.663AlaThr: 7.663 ± 3.567
6.386AlaVal: 6.386 ± 2.252
0.639AlaTrp: 0.639 ± 0.38
0.639AlaTyr: 0.639 ± 0.602
0.0AlaXaa: 0.0 ± 0.0
Cys
1.916CysAla: 1.916 ± 1.139
0.639CysCys: 0.639 ± 0.38
1.277CysAsp: 1.277 ± 0.51
1.277CysGlu: 1.277 ± 0.919
0.639CysPhe: 0.639 ± 0.38
0.639CysGly: 0.639 ± 0.38
0.0CysHis: 0.0 ± 0.0
0.639CysIle: 0.639 ± 0.38
0.0CysLys: 0.0 ± 0.0
1.916CysLeu: 1.916 ± 0.668
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.277CysPro: 1.277 ± 0.919
0.639CysGln: 0.639 ± 0.38
1.277CysArg: 1.277 ± 0.759
1.277CysSer: 1.277 ± 0.51
1.916CysThr: 1.916 ± 1.479
3.193CysVal: 3.193 ± 1.297
0.0CysTrp: 0.0 ± 0.0
0.639CysTyr: 0.639 ± 0.904
0.0CysXaa: 0.0 ± 0.0
Asp
2.554AspAla: 2.554 ± 1.13
2.554AspCys: 2.554 ± 1.519
1.277AspAsp: 1.277 ± 0.51
3.193AspGlu: 3.193 ± 1.794
1.277AspPhe: 1.277 ± 0.787
3.831AspGly: 3.831 ± 1.595
0.639AspHis: 0.639 ± 0.602
2.554AspIle: 2.554 ± 0.608
2.554AspLys: 2.554 ± 1.02
4.47AspLeu: 4.47 ± 1.225
0.0AspMet: 0.0 ± 0.0
1.277AspAsn: 1.277 ± 1.128
1.277AspPro: 1.277 ± 0.51
2.554AspGln: 2.554 ± 1.141
3.831AspArg: 3.831 ± 0.912
5.747AspSer: 5.747 ± 0.648
1.916AspThr: 1.916 ± 1.652
3.831AspVal: 3.831 ± 0.96
0.0AspTrp: 0.0 ± 0.0
0.639AspTyr: 0.639 ± 0.38
0.0AspXaa: 0.0 ± 0.0
Glu
3.193GluAla: 3.193 ± 0.713
0.639GluCys: 0.639 ± 0.38
3.831GluAsp: 3.831 ± 1.31
2.554GluGlu: 2.554 ± 1.043
1.277GluPhe: 1.277 ± 0.759
3.193GluGly: 3.193 ± 0.839
0.639GluHis: 0.639 ± 0.38
1.916GluIle: 1.916 ± 0.842
2.554GluLys: 2.554 ± 1.057
5.747GluLeu: 5.747 ± 2.091
1.916GluMet: 1.916 ± 1.75
0.639GluAsn: 0.639 ± 0.38
1.916GluPro: 1.916 ± 0.668
2.554GluGln: 2.554 ± 1.13
5.109GluArg: 5.109 ± 2.114
6.386GluSer: 6.386 ± 3.659
4.47GluThr: 4.47 ± 1.605
4.47GluVal: 4.47 ± 0.614
1.916GluTrp: 1.916 ± 0.915
1.916GluTyr: 1.916 ± 0.725
0.0GluXaa: 0.0 ± 0.0
Phe
0.639PheAla: 0.639 ± 0.38
1.916PheCys: 1.916 ± 0.668
3.193PheAsp: 3.193 ± 0.915
1.277PheGlu: 1.277 ± 1.505
1.277PhePhe: 1.277 ± 1.128
5.747PheGly: 5.747 ± 2.2
0.0PheHis: 0.0 ± 0.0
1.916PheIle: 1.916 ± 1.049
3.193PheLys: 3.193 ± 2.865
3.193PheLeu: 3.193 ± 1.586
1.277PheMet: 1.277 ± 0.759
1.277PheAsn: 1.277 ± 0.51
0.639PhePro: 0.639 ± 0.602
2.554PheGln: 2.554 ± 0.959
2.554PheArg: 2.554 ± 0.689
2.554PheSer: 2.554 ± 1.557
1.277PheThr: 1.277 ± 1.204
3.193PheVal: 3.193 ± 1.126
0.639PheTrp: 0.639 ± 0.38
1.277PheTyr: 1.277 ± 0.759
0.0PheXaa: 0.0 ± 0.0
Gly
5.747GlyAla: 5.747 ± 3.147
3.193GlyCys: 3.193 ± 1.794
5.109GlyAsp: 5.109 ± 1.53
1.916GlyGlu: 1.916 ± 1.139
4.47GlyPhe: 4.47 ± 3.105
8.94GlyGly: 8.94 ± 3.06
0.0GlyHis: 0.0 ± 0.0
3.193GlyIle: 3.193 ± 1.536
5.109GlyLys: 5.109 ± 0.803
6.386GlyLeu: 6.386 ± 1.94
1.916GlyMet: 1.916 ± 1.359
3.831GlyAsn: 3.831 ± 0.63
1.277GlyPro: 1.277 ± 0.51
0.639GlyGln: 0.639 ± 0.602
5.109GlyArg: 5.109 ± 2.07
5.747GlySer: 5.747 ± 2.32
5.747GlyThr: 5.747 ± 3.552
6.386GlyVal: 6.386 ± 1.431
0.639GlyTrp: 0.639 ± 0.38
5.109GlyTyr: 5.109 ± 1.621
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
3.193HisCys: 3.193 ± 0.708
0.0HisAsp: 0.0 ± 0.0
0.639HisGlu: 0.639 ± 0.38
0.0HisPhe: 0.0 ± 0.0
1.277HisGly: 1.277 ± 0.759
0.639HisHis: 0.639 ± 0.38
0.639HisIle: 0.639 ± 0.38
1.277HisLys: 1.277 ± 0.51
2.554HisLeu: 2.554 ± 1.13
1.277HisMet: 1.277 ± 0.759
1.916HisAsn: 1.916 ± 0.915
0.639HisPro: 0.639 ± 0.38
0.639HisGln: 0.639 ± 0.38
1.916HisArg: 1.916 ± 0.854
0.639HisSer: 0.639 ± 0.38
0.0HisThr: 0.0 ± 0.0
0.639HisVal: 0.639 ± 0.602
0.0HisTrp: 0.0 ± 0.0
0.639HisTyr: 0.639 ± 0.602
0.0HisXaa: 0.0 ± 0.0
Ile
3.193IleAla: 3.193 ± 1.126
0.639IleCys: 0.639 ± 0.38
1.277IleAsp: 1.277 ± 0.51
1.916IleGlu: 1.916 ± 0.915
3.193IlePhe: 3.193 ± 1.297
2.554IleGly: 2.554 ± 0.689
0.0IleHis: 0.0 ± 0.0
1.277IleIle: 1.277 ± 0.787
2.554IleLys: 2.554 ± 0.608
1.277IleLeu: 1.277 ± 0.759
1.916IleMet: 1.916 ± 0.901
3.193IleAsn: 3.193 ± 1.126
3.831IlePro: 3.831 ± 0.96
1.916IleGln: 1.916 ± 0.915
3.193IleArg: 3.193 ± 2.764
3.193IleSer: 3.193 ± 1.687
3.831IleThr: 3.831 ± 0.926
3.831IleVal: 3.831 ± 0.799
0.639IleTrp: 0.639 ± 0.38
1.277IleTyr: 1.277 ± 0.51
0.0IleXaa: 0.0 ± 0.0
Lys
4.47LysAla: 4.47 ± 1.34
0.0LysCys: 0.0 ± 0.0
3.193LysAsp: 3.193 ± 1.297
3.831LysGlu: 3.831 ± 1.823
1.277LysPhe: 1.277 ± 0.51
4.47LysGly: 4.47 ± 2.658
0.639LysHis: 0.639 ± 0.38
3.193LysIle: 3.193 ± 0.708
3.193LysLys: 3.193 ± 1.388
8.301LysLeu: 8.301 ± 2.107
0.639LysMet: 0.639 ± 0.38
2.554LysAsn: 2.554 ± 0.608
1.916LysPro: 1.916 ± 0.725
2.554LysGln: 2.554 ± 1.157
4.47LysArg: 4.47 ± 1.21
0.0LysSer: 0.0 ± 0.0
1.277LysThr: 1.277 ± 0.787
5.109LysVal: 5.109 ± 2.42
2.554LysTrp: 2.554 ± 1.043
0.0LysTyr: 0.0 ± 0.0
0.639LysXaa: 0.639 ± 0.38
Leu
9.579LeuAla: 9.579 ± 2.483
1.277LeuCys: 1.277 ± 1.128
3.193LeuAsp: 3.193 ± 1.388
3.831LeuGlu: 3.831 ± 1.647
1.916LeuPhe: 1.916 ± 0.725
9.579LeuGly: 9.579 ± 0.73
3.831LeuHis: 3.831 ± 1.823
2.554LeuIle: 2.554 ± 1.02
5.109LeuLys: 5.109 ± 1.621
9.579LeuLeu: 9.579 ± 1.434
1.277LeuMet: 1.277 ± 0.759
1.916LeuAsn: 1.916 ± 1.049
6.386LeuPro: 6.386 ± 0.828
3.193LeuGln: 3.193 ± 1.965
5.747LeuArg: 5.747 ± 1.218
7.024LeuSer: 7.024 ± 1.644
6.386LeuThr: 6.386 ± 1.992
6.386LeuVal: 6.386 ± 1.325
0.639LeuTrp: 0.639 ± 0.38
2.554LeuTyr: 2.554 ± 1.557
0.0LeuXaa: 0.0 ± 0.0
Met
2.554MetAla: 2.554 ± 1.926
0.639MetCys: 0.639 ± 0.38
1.916MetAsp: 1.916 ± 0.842
3.193MetGlu: 3.193 ± 1.102
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.554MetIle: 2.554 ± 1.02
1.916MetLys: 1.916 ± 1.139
0.639MetLeu: 0.639 ± 0.602
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.639MetGln: 0.639 ± 0.904
1.916MetArg: 1.916 ± 0.842
1.277MetSer: 1.277 ± 0.759
1.277MetThr: 1.277 ± 0.51
2.554MetVal: 2.554 ± 0.959
0.0MetTrp: 0.0 ± 0.0
1.277MetTyr: 1.277 ± 0.787
0.0MetXaa: 0.0 ± 0.0
Asn
1.916AsnAla: 1.916 ± 0.668
1.916AsnCys: 1.916 ± 0.725
1.916AsnAsp: 1.916 ± 2.113
1.916AsnGlu: 1.916 ± 0.842
1.277AsnPhe: 1.277 ± 0.985
2.554AsnGly: 2.554 ± 1.632
1.277AsnHis: 1.277 ± 0.51
2.554AsnIle: 2.554 ± 0.959
2.554AsnLys: 2.554 ± 1.574
3.193AsnLeu: 3.193 ± 1.126
0.0AsnMet: 0.0 ± 0.0
3.193AsnAsn: 3.193 ± 2.226
1.916AsnPro: 1.916 ± 0.854
0.639AsnGln: 0.639 ± 1.068
1.916AsnArg: 1.916 ± 1.139
3.831AsnSer: 3.831 ± 2.228
1.916AsnThr: 1.916 ± 1.049
4.47AsnVal: 4.47 ± 0.614
0.0AsnTrp: 0.0 ± 0.0
1.916AsnTyr: 1.916 ± 0.854
0.0AsnXaa: 0.0 ± 0.0
Pro
2.554ProAla: 2.554 ± 1.02
0.0ProCys: 0.0 ± 0.0
1.916ProAsp: 1.916 ± 0.915
3.193ProGlu: 3.193 ± 0.713
1.916ProPhe: 1.916 ± 1.275
1.916ProGly: 1.916 ± 0.668
0.0ProHis: 0.0 ± 0.0
2.554ProIle: 2.554 ± 1.13
1.916ProLys: 1.916 ± 0.668
5.109ProLeu: 5.109 ± 1.271
0.0ProMet: 0.0 ± 0.0
0.639ProAsn: 0.639 ± 0.38
0.639ProPro: 0.639 ± 0.38
2.554ProGln: 2.554 ± 0.608
4.47ProArg: 4.47 ± 2.658
5.109ProSer: 5.109 ± 1.248
1.916ProThr: 1.916 ± 1.049
5.109ProVal: 5.109 ± 1.919
1.277ProTrp: 1.277 ± 0.985
0.639ProTyr: 0.639 ± 0.38
0.0ProXaa: 0.0 ± 0.0
Gln
1.916GlnAla: 1.916 ± 0.915
0.0GlnCys: 0.0 ± 0.0
0.639GlnAsp: 0.639 ± 1.068
3.193GlnGlu: 3.193 ± 1.831
1.277GlnPhe: 1.277 ± 0.787
1.916GlnGly: 1.916 ± 0.854
2.554GlnHis: 2.554 ± 1.13
1.916GlnIle: 1.916 ± 0.915
0.0GlnLys: 0.0 ± 0.0
5.747GlnLeu: 5.747 ± 1.616
0.639GlnMet: 0.639 ± 0.602
0.639GlnAsn: 0.639 ± 0.602
2.554GlnPro: 2.554 ± 0.959
0.639GlnGln: 0.639 ± 0.602
2.554GlnArg: 2.554 ± 1.519
0.639GlnSer: 0.639 ± 0.904
0.0GlnThr: 0.0 ± 0.0
2.554GlnVal: 2.554 ± 1.075
0.0GlnTrp: 0.0 ± 0.0
1.277GlnTyr: 1.277 ± 0.51
0.0GlnXaa: 0.0 ± 0.0
Arg
7.663ArgAla: 7.663 ± 1.87
0.639ArgCys: 0.639 ± 0.602
3.193ArgAsp: 3.193 ± 1.325
4.47ArgGlu: 4.47 ± 1.385
4.47ArgPhe: 4.47 ± 1.504
3.831ArgGly: 3.831 ± 1.543
1.277ArgHis: 1.277 ± 0.759
1.916ArgIle: 1.916 ± 1.652
3.193ArgLys: 3.193 ± 1.586
6.386ArgLeu: 6.386 ± 1.431
1.277ArgMet: 1.277 ± 0.759
3.831ArgAsn: 3.831 ± 1.654
2.554ArgPro: 2.554 ± 1.043
1.916ArgGln: 1.916 ± 1.049
5.747ArgArg: 5.747 ± 1.282
1.277ArgSer: 1.277 ± 1.505
7.663ArgThr: 7.663 ± 1.823
7.024ArgVal: 7.024 ± 0.51
1.916ArgTrp: 1.916 ± 1.275
3.831ArgTyr: 3.831 ± 1.83
0.0ArgXaa: 0.0 ± 0.0
Ser
3.193SerAla: 3.193 ± 1.126
0.0SerCys: 0.0 ± 0.0
3.193SerAsp: 3.193 ± 1.388
2.554SerGlu: 2.554 ± 1.866
1.916SerPhe: 1.916 ± 1.139
6.386SerGly: 6.386 ± 2.014
0.639SerHis: 0.639 ± 0.38
4.47SerIle: 4.47 ± 1.605
5.747SerLys: 5.747 ± 3.141
5.109SerLeu: 5.109 ± 1.248
0.639SerMet: 0.639 ± 0.38
3.831SerAsn: 3.831 ± 2.128
3.193SerPro: 3.193 ± 2.031
1.916SerGln: 1.916 ± 0.668
5.747SerArg: 5.747 ± 2.477
1.277SerSer: 1.277 ± 0.985
5.747SerThr: 5.747 ± 3.087
8.301SerVal: 8.301 ± 2.382
2.554SerTrp: 2.554 ± 3.153
2.554SerTyr: 2.554 ± 0.959
0.0SerXaa: 0.0 ± 0.0
Thr
4.47ThrAla: 4.47 ± 2.677
0.639ThrCys: 0.639 ± 0.38
3.193ThrAsp: 3.193 ± 0.868
4.47ThrGlu: 4.47 ± 3.539
4.47ThrPhe: 4.47 ± 1.933
8.94ThrGly: 8.94 ± 2.069
0.639ThrHis: 0.639 ± 0.602
1.277ThrIle: 1.277 ± 0.759
3.831ThrLys: 3.831 ± 0.799
5.109ThrLeu: 5.109 ± 1.826
2.554ThrMet: 2.554 ± 1.557
2.554ThrAsn: 2.554 ± 1.157
1.916ThrPro: 1.916 ± 1.139
0.639ThrGln: 0.639 ± 0.38
4.47ThrArg: 4.47 ± 1.225
4.47ThrSer: 4.47 ± 1.933
4.47ThrThr: 4.47 ± 1.585
5.747ThrVal: 5.747 ± 2.379
0.0ThrTrp: 0.0 ± 0.0
3.193ThrTyr: 3.193 ± 0.915
0.0ThrXaa: 0.0 ± 0.0
Val
4.47ValAla: 4.47 ± 1.609
1.277ValCys: 1.277 ± 0.759
3.193ValAsp: 3.193 ± 1.126
9.579ValGlu: 9.579 ± 3.419
3.831ValPhe: 3.831 ± 1.201
7.024ValGly: 7.024 ± 2.206
3.193ValHis: 3.193 ± 1.297
2.554ValIle: 2.554 ± 0.959
3.193ValLys: 3.193 ± 1.126
5.747ValLeu: 5.747 ± 0.648
1.916ValMet: 1.916 ± 1.391
6.386ValAsn: 6.386 ± 1.783
6.386ValPro: 6.386 ± 1.416
0.639ValGln: 0.639 ± 0.38
7.024ValArg: 7.024 ± 1.644
8.301ValSer: 8.301 ± 4.463
5.747ValThr: 5.747 ± 3.147
5.747ValVal: 5.747 ± 1.188
0.0ValTrp: 0.0 ± 0.0
1.277ValTyr: 1.277 ± 0.759
0.0ValXaa: 0.0 ± 0.0
Trp
1.277TrpAla: 1.277 ± 0.51
0.0TrpCys: 0.0 ± 0.0
1.277TrpAsp: 1.277 ± 0.919
1.277TrpGlu: 1.277 ± 0.759
0.639TrpPhe: 0.639 ± 0.38
1.277TrpGly: 1.277 ± 0.919
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.277TrpLys: 1.277 ± 0.787
0.639TrpLeu: 0.639 ± 0.602
0.0TrpMet: 0.0 ± 0.0
0.639TrpAsn: 0.639 ± 0.904
0.639TrpPro: 0.639 ± 0.38
1.277TrpGln: 1.277 ± 0.787
1.277TrpArg: 1.277 ± 0.919
0.639TrpSer: 0.639 ± 0.38
1.277TrpThr: 1.277 ± 2.137
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.554TyrAla: 2.554 ± 1.057
0.0TyrCys: 0.0 ± 0.0
1.916TyrAsp: 1.916 ± 0.915
1.277TyrGlu: 1.277 ± 0.787
1.916TyrPhe: 1.916 ± 1.049
0.639TyrGly: 0.639 ± 0.602
0.0TyrHis: 0.0 ± 0.0
1.277TyrIle: 1.277 ± 0.787
1.277TyrLys: 1.277 ± 0.985
4.47TyrLeu: 4.47 ± 0.55
1.277TyrMet: 1.277 ± 0.759
0.639TyrAsn: 0.639 ± 0.38
1.277TyrPro: 1.277 ± 0.759
1.277TyrGln: 1.277 ± 0.787
1.916TyrArg: 1.916 ± 0.668
3.831TyrSer: 3.831 ± 0.926
2.554TyrThr: 2.554 ± 0.959
2.554TyrVal: 2.554 ± 0.959
0.0TyrTrp: 0.0 ± 0.0
0.639TyrTyr: 0.639 ± 0.38
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.639XaaGly: 0.639 ± 0.38
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1567 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski