Amino acid dipepetide frequency for Carnation yellow fleck virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.275AlaAla: 5.275 ± 1.155
1.368AlaCys: 1.368 ± 0.298
3.322AlaAsp: 3.322 ± 1.455
2.735AlaGlu: 2.735 ± 0.977
4.885AlaPhe: 4.885 ± 0.453
1.954AlaGly: 1.954 ± 0.58
1.368AlaHis: 1.368 ± 0.344
2.54AlaIle: 2.54 ± 0.627
4.299AlaLys: 4.299 ± 0.861
6.252AlaLeu: 6.252 ± 0.729
0.977AlaMet: 0.977 ± 0.548
1.758AlaAsn: 1.758 ± 0.484
1.758AlaPro: 1.758 ± 0.593
2.149AlaGln: 2.149 ± 0.433
4.103AlaArg: 4.103 ± 0.816
6.839AlaSer: 6.839 ± 0.819
2.735AlaThr: 2.735 ± 0.905
4.494AlaVal: 4.494 ± 0.869
0.391AlaTrp: 0.391 ± 0.25
2.735AlaTyr: 2.735 ± 0.57
0.0AlaXaa: 0.0 ± 0.0
Cys
2.149CysAla: 2.149 ± 0.51
1.172CysCys: 1.172 ± 0.457
1.563CysAsp: 1.563 ± 0.645
1.172CysGlu: 1.172 ± 0.178
1.172CysPhe: 1.172 ± 0.268
1.368CysGly: 1.368 ± 0.659
0.586CysHis: 0.586 ± 0.268
0.977CysIle: 0.977 ± 0.348
1.368CysLys: 1.368 ± 0.489
3.322CysLeu: 3.322 ± 0.823
0.195CysMet: 0.195 ± 0.262
0.586CysAsn: 0.586 ± 0.197
0.782CysPro: 0.782 ± 0.414
0.195CysGln: 0.195 ± 0.186
1.368CysArg: 1.368 ± 0.412
2.54CysSer: 2.54 ± 0.542
0.391CysThr: 0.391 ± 0.311
1.172CysVal: 1.172 ± 0.547
0.195CysTrp: 0.195 ± 0.255
0.977CysTyr: 0.977 ± 0.214
0.0CysXaa: 0.0 ± 0.0
Asp
4.103AspAla: 4.103 ± 0.718
1.563AspCys: 1.563 ± 0.604
4.103AspAsp: 4.103 ± 0.77
3.517AspGlu: 3.517 ± 0.774
4.103AspPhe: 4.103 ± 0.883
0.977AspGly: 0.977 ± 0.306
1.172AspHis: 1.172 ± 0.338
1.563AspIle: 1.563 ± 0.315
1.172AspLys: 1.172 ± 0.327
5.275AspLeu: 5.275 ± 0.604
0.391AspMet: 0.391 ± 0.306
2.345AspAsn: 2.345 ± 0.937
0.977AspPro: 0.977 ± 0.315
0.586AspGln: 0.586 ± 0.312
2.345AspArg: 2.345 ± 0.552
6.252AspSer: 6.252 ± 0.933
1.758AspThr: 1.758 ± 0.566
5.08AspVal: 5.08 ± 0.775
0.0AspTrp: 0.0 ± 0.0
2.54AspTyr: 2.54 ± 0.546
0.0AspXaa: 0.0 ± 0.0
Glu
3.712GluAla: 3.712 ± 0.777
1.172GluCys: 1.172 ± 0.447
2.345GluAsp: 2.345 ± 0.761
3.322GluGlu: 3.322 ± 0.777
4.689GluPhe: 4.689 ± 0.735
1.758GluGly: 1.758 ± 0.42
0.391GluHis: 0.391 ± 0.219
3.126GluIle: 3.126 ± 0.729
3.517GluLys: 3.517 ± 0.67
6.643GluLeu: 6.643 ± 1.996
0.977GluMet: 0.977 ± 0.386
3.908GluAsn: 3.908 ± 0.718
2.345GluPro: 2.345 ± 0.396
1.172GluGln: 1.172 ± 0.381
4.494GluArg: 4.494 ± 1.018
6.252GluSer: 6.252 ± 0.689
1.758GluThr: 1.758 ± 0.386
5.08GluVal: 5.08 ± 0.353
0.782GluTrp: 0.782 ± 0.28
2.735GluTyr: 2.735 ± 0.8
0.0GluXaa: 0.0 ± 0.0
Phe
2.54PheAla: 2.54 ± 0.589
3.322PheCys: 3.322 ± 0.459
2.54PheAsp: 2.54 ± 0.738
3.908PheGlu: 3.908 ± 1.087
5.275PhePhe: 5.275 ± 0.991
3.712PheGly: 3.712 ± 1.044
2.54PheHis: 2.54 ± 0.547
2.931PheIle: 2.931 ± 0.477
3.517PheLys: 3.517 ± 0.586
8.792PheLeu: 8.792 ± 1.248
0.391PheMet: 0.391 ± 0.207
2.345PheAsn: 2.345 ± 0.661
1.172PhePro: 1.172 ± 0.268
1.368PheGln: 1.368 ± 0.265
2.931PheArg: 2.931 ± 0.57
7.034PheSer: 7.034 ± 1.057
3.322PheThr: 3.322 ± 0.607
5.275PheVal: 5.275 ± 0.763
0.195PheTrp: 0.195 ± 0.103
1.954PheTyr: 1.954 ± 0.488
0.0PheXaa: 0.0 ± 0.0
Gly
3.517GlyAla: 3.517 ± 0.66
1.368GlyCys: 1.368 ± 0.298
3.517GlyAsp: 3.517 ± 0.664
4.689GlyGlu: 4.689 ± 0.903
3.322GlyPhe: 3.322 ± 0.684
5.08GlyGly: 5.08 ± 1.201
0.195GlyHis: 0.195 ± 0.221
1.758GlyIle: 1.758 ± 1.015
3.126GlyLys: 3.126 ± 0.942
4.885GlyLeu: 4.885 ± 0.738
0.586GlyMet: 0.586 ± 0.197
1.368GlyAsn: 1.368 ± 0.293
1.172GlyPro: 1.172 ± 0.291
0.586GlyGln: 0.586 ± 0.475
2.345GlyArg: 2.345 ± 0.562
4.689GlySer: 4.689 ± 0.976
2.931GlyThr: 2.931 ± 1.568
2.345GlyVal: 2.345 ± 0.664
0.391GlyTrp: 0.391 ± 0.342
1.368GlyTyr: 1.368 ± 0.544
0.0GlyXaa: 0.0 ± 0.0
His
1.172HisAla: 1.172 ± 0.614
1.368HisCys: 1.368 ± 0.809
0.586HisAsp: 0.586 ± 0.246
0.782HisGlu: 0.782 ± 0.289
0.782HisPhe: 0.782 ± 0.256
0.586HisGly: 0.586 ± 0.291
0.195HisHis: 0.195 ± 0.288
0.977HisIle: 0.977 ± 0.517
0.977HisLys: 0.977 ± 0.352
1.368HisLeu: 1.368 ± 0.435
0.0HisMet: 0.0 ± 0.0
0.391HisAsn: 0.391 ± 0.306
1.368HisPro: 1.368 ± 0.525
0.586HisGln: 0.586 ± 0.34
1.368HisArg: 1.368 ± 0.338
0.977HisSer: 0.977 ± 0.29
1.172HisThr: 1.172 ± 0.429
1.563HisVal: 1.563 ± 0.509
0.0HisTrp: 0.0 ± 0.0
0.391HisTyr: 0.391 ± 0.228
0.0HisXaa: 0.0 ± 0.0
Ile
3.517IleAla: 3.517 ± 0.579
0.391IleCys: 0.391 ± 0.365
2.735IleAsp: 2.735 ± 0.49
2.345IleGlu: 2.345 ± 0.68
2.54IlePhe: 2.54 ± 0.692
1.758IleGly: 1.758 ± 0.669
1.368IleHis: 1.368 ± 0.179
0.782IleIle: 0.782 ± 0.277
2.149IleLys: 2.149 ± 0.496
4.494IleLeu: 4.494 ± 0.706
0.782IleMet: 0.782 ± 0.213
2.54IleAsn: 2.54 ± 0.845
2.735IlePro: 2.735 ± 0.683
0.782IleGln: 0.782 ± 0.535
2.345IleArg: 2.345 ± 0.479
3.712IleSer: 3.712 ± 0.534
2.54IleThr: 2.54 ± 0.586
4.103IleVal: 4.103 ± 0.817
0.195IleTrp: 0.195 ± 0.103
0.195IleTyr: 0.195 ± 0.103
0.0IleXaa: 0.0 ± 0.0
Lys
2.149LysAla: 2.149 ± 0.486
1.172LysCys: 1.172 ± 0.381
2.735LysAsp: 2.735 ± 0.756
3.517LysGlu: 3.517 ± 0.658
4.885LysPhe: 4.885 ± 0.697
1.954LysGly: 1.954 ± 0.475
1.563LysHis: 1.563 ± 0.358
3.517LysIle: 3.517 ± 0.948
3.517LysLys: 3.517 ± 0.413
6.448LysLeu: 6.448 ± 1.502
0.0LysMet: 0.0 ± 0.0
3.908LysAsn: 3.908 ± 0.664
2.149LysPro: 2.149 ± 0.479
0.782LysGln: 0.782 ± 0.335
3.517LysArg: 3.517 ± 0.774
4.885LysSer: 4.885 ± 0.728
5.275LysThr: 5.275 ± 0.919
5.666LysVal: 5.666 ± 1.032
0.0LysTrp: 0.0 ± 0.0
1.563LysTyr: 1.563 ± 0.478
0.0LysXaa: 0.0 ± 0.0
Leu
5.666LeuAla: 5.666 ± 1.086
1.758LeuCys: 1.758 ± 0.513
4.689LeuAsp: 4.689 ± 0.852
4.494LeuGlu: 4.494 ± 0.754
4.494LeuPhe: 4.494 ± 0.597
5.275LeuGly: 5.275 ± 1.338
1.368LeuHis: 1.368 ± 0.448
3.712LeuIle: 3.712 ± 0.605
7.62LeuLys: 7.62 ± 1.087
14.459LeuLeu: 14.459 ± 1.328
1.172LeuMet: 1.172 ± 0.304
6.839LeuAsn: 6.839 ± 0.953
4.299LeuPro: 4.299 ± 1.145
4.103LeuGln: 4.103 ± 0.848
7.62LeuArg: 7.62 ± 1.559
13.286LeuSer: 13.286 ± 0.934
9.965LeuThr: 9.965 ± 0.799
5.275LeuVal: 5.275 ± 0.579
0.195LeuTrp: 0.195 ± 0.255
3.908LeuTyr: 3.908 ± 0.93
0.0LeuXaa: 0.0 ± 0.0
Met
0.391MetAla: 0.391 ± 0.182
0.586MetCys: 0.586 ± 0.561
0.195MetAsp: 0.195 ± 0.281
0.391MetGlu: 0.391 ± 0.182
1.172MetPhe: 1.172 ± 0.385
0.782MetGly: 0.782 ± 0.414
0.195MetHis: 0.195 ± 0.288
0.782MetIle: 0.782 ± 0.263
0.586MetLys: 0.586 ± 0.363
1.563MetLeu: 1.563 ± 0.387
0.0MetMet: 0.0 ± 0.0
0.782MetAsn: 0.782 ± 0.286
0.586MetPro: 0.586 ± 0.32
0.195MetGln: 0.195 ± 0.221
0.977MetArg: 0.977 ± 0.325
0.391MetSer: 0.391 ± 0.157
1.172MetThr: 1.172 ± 0.633
1.368MetVal: 1.368 ± 0.572
0.0MetTrp: 0.0 ± 0.0
0.195MetTyr: 0.195 ± 0.103
0.0MetXaa: 0.0 ± 0.0
Asn
3.908AsnAla: 3.908 ± 0.763
0.977AsnCys: 0.977 ± 0.48
1.758AsnAsp: 1.758 ± 0.674
2.735AsnGlu: 2.735 ± 0.689
2.345AsnPhe: 2.345 ± 0.693
0.977AsnGly: 0.977 ± 0.435
0.195AsnHis: 0.195 ± 0.103
2.735AsnIle: 2.735 ± 0.559
2.345AsnLys: 2.345 ± 0.643
5.862AsnLeu: 5.862 ± 0.762
0.977AsnMet: 0.977 ± 0.845
1.758AsnAsn: 1.758 ± 0.401
1.563AsnPro: 1.563 ± 1.432
0.586AsnGln: 0.586 ± 0.229
3.517AsnArg: 3.517 ± 0.676
5.08AsnSer: 5.08 ± 0.878
2.735AsnThr: 2.735 ± 0.685
4.103AsnVal: 4.103 ± 1.396
0.195AsnTrp: 0.195 ± 0.103
2.735AsnTyr: 2.735 ± 0.72
0.0AsnXaa: 0.0 ± 0.0
Pro
1.954ProAla: 1.954 ± 0.419
0.195ProCys: 0.195 ± 0.221
0.977ProAsp: 0.977 ± 0.226
1.954ProGlu: 1.954 ± 0.516
2.931ProPhe: 2.931 ± 0.642
2.931ProGly: 2.931 ± 1.032
0.782ProHis: 0.782 ± 0.414
1.368ProIle: 1.368 ± 0.34
2.345ProLys: 2.345 ± 0.594
4.103ProLeu: 4.103 ± 0.543
0.391ProMet: 0.391 ± 0.372
1.563ProAsn: 1.563 ± 0.498
1.954ProPro: 1.954 ± 0.402
1.172ProGln: 1.172 ± 0.372
2.735ProArg: 2.735 ± 0.695
3.322ProSer: 3.322 ± 0.804
2.931ProThr: 2.931 ± 0.512
2.931ProVal: 2.931 ± 0.436
0.195ProTrp: 0.195 ± 0.103
1.172ProTyr: 1.172 ± 0.364
0.0ProXaa: 0.0 ± 0.0
Gln
1.368GlnAla: 1.368 ± 0.293
0.391GlnCys: 0.391 ± 0.157
0.782GlnAsp: 0.782 ± 0.396
1.172GlnGlu: 1.172 ± 0.325
1.172GlnPhe: 1.172 ± 0.322
1.172GlnGly: 1.172 ± 0.294
0.195GlnHis: 0.195 ± 0.103
0.391GlnIle: 0.391 ± 0.207
0.782GlnLys: 0.782 ± 0.386
2.54GlnLeu: 2.54 ± 0.477
0.0GlnMet: 0.0 ± 0.0
1.172GlnAsn: 1.172 ± 0.742
1.758GlnPro: 1.758 ± 0.701
0.391GlnGln: 0.391 ± 0.366
2.931GlnArg: 2.931 ± 0.961
1.563GlnSer: 1.563 ± 0.675
0.782GlnThr: 0.782 ± 0.287
1.368GlnVal: 1.368 ± 0.383
0.0GlnTrp: 0.0 ± 0.0
0.391GlnTyr: 0.391 ± 0.256
0.0GlnXaa: 0.0 ± 0.0
Arg
5.08ArgAla: 5.08 ± 1.169
0.391ArgCys: 0.391 ± 0.207
3.126ArgAsp: 3.126 ± 0.356
5.08ArgGlu: 5.08 ± 1.28
4.494ArgPhe: 4.494 ± 0.844
3.517ArgGly: 3.517 ± 0.77
0.195ArgHis: 0.195 ± 0.103
2.345ArgIle: 2.345 ± 0.764
4.299ArgLys: 4.299 ± 0.71
4.885ArgLeu: 4.885 ± 0.729
0.977ArgMet: 0.977 ± 0.345
3.517ArgAsn: 3.517 ± 0.37
1.563ArgPro: 1.563 ± 0.629
0.586ArgGln: 0.586 ± 0.229
4.299ArgArg: 4.299 ± 1.537
7.816ArgSer: 7.816 ± 1.212
4.494ArgThr: 4.494 ± 0.934
5.275ArgVal: 5.275 ± 1.572
0.391ArgTrp: 0.391 ± 0.306
1.563ArgTyr: 1.563 ± 0.633
0.0ArgXaa: 0.0 ± 0.0
Ser
8.206SerAla: 8.206 ± 1.224
1.954SerCys: 1.954 ± 0.508
6.448SerAsp: 6.448 ± 1.053
6.643SerGlu: 6.643 ± 1.263
6.448SerPhe: 6.448 ± 0.819
6.057SerGly: 6.057 ± 0.823
1.172SerHis: 1.172 ± 0.29
3.322SerIle: 3.322 ± 0.315
5.275SerLys: 5.275 ± 1.195
10.356SerLeu: 10.356 ± 1.671
1.172SerMet: 1.172 ± 0.424
5.275SerAsn: 5.275 ± 1.275
3.517SerPro: 3.517 ± 0.723
1.954SerGln: 1.954 ± 0.764
5.666SerArg: 5.666 ± 1.052
10.942SerSer: 10.942 ± 1.282
4.494SerThr: 4.494 ± 0.56
9.379SerVal: 9.379 ± 1.881
0.782SerTrp: 0.782 ± 0.28
4.299SerTyr: 4.299 ± 0.369
0.0SerXaa: 0.0 ± 0.0
Thr
2.345ThrAla: 2.345 ± 0.626
1.368ThrCys: 1.368 ± 0.273
1.563ThrAsp: 1.563 ± 0.689
3.517ThrGlu: 3.517 ± 0.56
5.862ThrPhe: 5.862 ± 0.852
2.931ThrGly: 2.931 ± 0.746
0.782ThrHis: 0.782 ± 0.256
3.126ThrIle: 3.126 ± 0.774
3.126ThrLys: 3.126 ± 0.432
5.471ThrLeu: 5.471 ± 1.022
0.977ThrMet: 0.977 ± 0.347
2.149ThrAsn: 2.149 ± 0.699
2.345ThrPro: 2.345 ± 0.607
0.977ThrGln: 0.977 ± 0.446
3.322ThrArg: 3.322 ± 0.727
6.057ThrSer: 6.057 ± 0.889
4.494ThrThr: 4.494 ± 0.682
4.299ThrVal: 4.299 ± 0.736
0.391ThrTrp: 0.391 ± 0.442
3.126ThrTyr: 3.126 ± 0.614
0.0ThrXaa: 0.0 ± 0.0
Val
3.712ValAla: 3.712 ± 0.732
1.758ValCys: 1.758 ± 0.44
3.517ValAsp: 3.517 ± 0.475
3.908ValGlu: 3.908 ± 0.889
2.931ValPhe: 2.931 ± 0.387
4.494ValGly: 4.494 ± 1.081
1.368ValHis: 1.368 ± 0.359
3.908ValIle: 3.908 ± 0.589
6.643ValLys: 6.643 ± 0.793
7.425ValLeu: 7.425 ± 1.737
1.368ValMet: 1.368 ± 0.405
3.517ValAsn: 3.517 ± 0.572
4.494ValPro: 4.494 ± 0.826
1.172ValGln: 1.172 ± 0.621
6.057ValArg: 6.057 ± 1.091
7.62ValSer: 7.62 ± 1.279
3.712ValThr: 3.712 ± 1.033
6.448ValVal: 6.448 ± 1.179
0.586ValTrp: 0.586 ± 0.337
3.126ValTyr: 3.126 ± 0.643
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.586TrpAsp: 0.586 ± 0.229
0.391TrpGlu: 0.391 ± 0.207
0.586TrpPhe: 0.586 ± 0.282
0.195TrpGly: 0.195 ± 0.255
0.0TrpHis: 0.0 ± 0.0
0.586TrpIle: 0.586 ± 0.446
0.586TrpLys: 0.586 ± 0.463
0.586TrpLeu: 0.586 ± 0.31
0.391TrpMet: 0.391 ± 0.442
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.586TrpSer: 0.586 ± 0.229
0.0TrpThr: 0.0 ± 0.0
0.586TrpVal: 0.586 ± 0.246
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.172TyrAla: 1.172 ± 0.441
0.977TyrCys: 0.977 ± 0.514
2.735TyrAsp: 2.735 ± 0.367
3.908TyrGlu: 3.908 ± 0.383
0.977TyrPhe: 0.977 ± 0.315
1.758TyrGly: 1.758 ± 0.809
0.977TyrHis: 0.977 ± 0.338
1.563TyrIle: 1.563 ± 0.49
1.954TyrLys: 1.954 ± 0.642
5.666TyrLeu: 5.666 ± 1.575
0.391TyrMet: 0.391 ± 0.157
1.368TyrAsn: 1.368 ± 0.713
1.368TyrPro: 1.368 ± 0.36
0.977TyrGln: 0.977 ± 0.352
1.954TyrArg: 1.954 ± 0.603
3.517TyrSer: 3.517 ± 0.353
1.563TyrThr: 1.563 ± 0.68
1.954TyrVal: 1.954 ± 0.513
0.195TyrTrp: 0.195 ± 0.103
1.563TyrTyr: 1.563 ± 0.417
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (5119 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski