Amino acid dipepetide frequency for Branchiibius sp. NY16-3462-2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.302AlaAla: 19.302 ± 0.185	0.93AlaCys: 0.93 ± 0.032	8.382AlaAsp: 8.382 ± 0.085	6.439AlaGlu: 6.439 ± 0.102	3.554AlaPhe: 3.554 ± 0.06	11.73AlaGly: 11.73 ± 0.129	2.482AlaHis: 2.482 ± 0.046	5.707AlaIle: 5.707 ± 0.079	3.172AlaLys: 3.172 ± 0.076	13.196AlaLeu: 13.196 ± 0.125	2.857AlaMet: 2.857 ± 0.056	2.388AlaAsn: 2.388 ± 0.048	5.84AlaPro: 5.84 ± 0.077	4.586AlaGln: 4.586 ± 0.062	8.174AlaArg: 8.174 ± 0.104	6.587AlaSer: 6.587 ± 0.093	7.951AlaThr: 7.951 ± 0.098	11.015AlaVal: 11.015 ± 0.114	1.879AlaTrp: 1.879 ± 0.047	2.608AlaTyr: 2.608 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.851CysAla: 0.851 ± 0.027	0.074CysCys: 0.074 ± 0.008	0.451CysAsp: 0.451 ± 0.022	0.348CysGlu: 0.348 ± 0.018	0.233CysPhe: 0.233 ± 0.013	0.828CysGly: 0.828 ± 0.028	0.146CysHis: 0.146 ± 0.011	0.264CysIle: 0.264 ± 0.017	0.103CysLys: 0.103 ± 0.009	0.594CysLeu: 0.594 ± 0.023	0.109CysMet: 0.109 ± 0.008	0.142CysAsn: 0.142 ± 0.011	0.43CysPro: 0.43 ± 0.024	0.183CysGln: 0.183 ± 0.013	0.473CysArg: 0.473 ± 0.022	0.474CysSer: 0.474 ± 0.019	0.473CysThr: 0.473 ± 0.024	0.595CysVal: 0.595 ± 0.023	0.138CysTrp: 0.138 ± 0.012	0.157CysTyr: 0.157 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.747AspAla: 7.747 ± 0.099	0.338AspCys: 0.338 ± 0.017	4.103AspAsp: 4.103 ± 0.074	4.136AspGlu: 4.136 ± 0.062	1.795AspPhe: 1.795 ± 0.042	6.014AspGly: 6.014 ± 0.087	1.39AspHis: 1.39 ± 0.039	2.267AspIle: 2.267 ± 0.052	1.414AspLys: 1.414 ± 0.038	7.188AspLeu: 7.188 ± 0.084	0.905AspMet: 0.905 ± 0.027	1.205AspAsn: 1.205 ± 0.036	4.516AspPro: 4.516 ± 0.074	2.218AspGln: 2.218 ± 0.042	4.518AspArg: 4.518 ± 0.066	2.82AspSer: 2.82 ± 0.055	3.07AspThr: 3.07 ± 0.051	5.45AspVal: 5.45 ± 0.067	1.073AspTrp: 1.073 ± 0.038	1.299AspTyr: 1.299 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	5.883GluAla: 5.883 ± 0.089	0.338GluCys: 0.338 ± 0.018	2.651GluAsp: 2.651 ± 0.054	2.549GluGlu: 2.549 ± 0.06	1.527GluPhe: 1.527 ± 0.039	3.594GluGly: 3.594 ± 0.065	1.525GluHis: 1.525 ± 0.037	2.275GluIle: 2.275 ± 0.051	1.424GluLys: 1.424 ± 0.066	5.714GluLeu: 5.714 ± 0.081	0.903GluMet: 0.903 ± 0.027	1.002GluAsn: 1.002 ± 0.032	2.883GluPro: 2.883 ± 0.06	2.534GluGln: 2.534 ± 0.052	4.238GluArg: 4.238 ± 0.076	2.556GluSer: 2.556 ± 0.049	2.617GluThr: 2.617 ± 0.057	4.531GluVal: 4.531 ± 0.074	0.8GluTrp: 0.8 ± 0.029	1.001GluTyr: 1.001 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.921PheAla: 3.921 ± 0.064	0.254PheCys: 0.254 ± 0.016	2.197PheAsp: 2.197 ± 0.041	1.626PheGlu: 1.626 ± 0.037	1.008PhePhe: 1.008 ± 0.034	3.214PheGly: 3.214 ± 0.059	0.575PheHis: 0.575 ± 0.022	1.118PheIle: 1.118 ± 0.039	0.608PheLys: 0.608 ± 0.026	2.695PheLeu: 2.695 ± 0.059	0.46PheMet: 0.46 ± 0.019	0.71PheAsn: 0.71 ± 0.024	1.367PhePro: 1.367 ± 0.035	0.723PheGln: 0.723 ± 0.027	1.57PheArg: 1.57 ± 0.039	1.646PheSer: 1.646 ± 0.037	2.015PheThr: 2.015 ± 0.042	2.666PheVal: 2.666 ± 0.058	0.477PheTrp: 0.477 ± 0.021	0.708PheTyr: 0.708 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.818GlyAla: 9.818 ± 0.105	0.756GlyCys: 0.756 ± 0.031	5.163GlyAsp: 5.163 ± 0.064	4.148GlyGlu: 4.148 ± 0.068	3.046GlyPhe: 3.046 ± 0.061	7.745GlyGly: 7.745 ± 0.118	1.997GlyHis: 1.997 ± 0.046	3.975GlyIle: 3.975 ± 0.069	2.531GlyLys: 2.531 ± 0.06	9.043GlyLeu: 9.043 ± 0.114	1.871GlyMet: 1.871 ± 0.037	1.91GlyAsn: 1.91 ± 0.052	4.039GlyPro: 4.039 ± 0.06	3.18GlyGln: 3.18 ± 0.058	5.891GlyArg: 5.891 ± 0.08	5.68GlySer: 5.68 ± 0.079	5.618GlyThr: 5.618 ± 0.077	7.876GlyVal: 7.876 ± 0.082	1.742GlyTrp: 1.742 ± 0.041	2.342GlyTyr: 2.342 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.309HisAla: 2.309 ± 0.049	0.187HisCys: 0.187 ± 0.012	1.405HisAsp: 1.405 ± 0.036	1.252HisGlu: 1.252 ± 0.036	0.617HisPhe: 0.617 ± 0.023	2.01HisGly: 2.01 ± 0.047	0.65HisHis: 0.65 ± 0.027	0.722HisIle: 0.722 ± 0.023	0.349HisLys: 0.349 ± 0.018	2.311HisLeu: 2.311 ± 0.048	0.3HisMet: 0.3 ± 0.016	0.416HisAsn: 0.416 ± 0.019	1.549HisPro: 1.549 ± 0.039	0.683HisGln: 0.683 ± 0.03	1.679HisArg: 1.679 ± 0.041	1.054HisSer: 1.054 ± 0.029	1.205HisThr: 1.205 ± 0.033	1.722HisVal: 1.722 ± 0.042	0.366HisTrp: 0.366 ± 0.017	0.467HisTyr: 0.467 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.332IleAla: 6.332 ± 0.09	0.367IleCys: 0.367 ± 0.018	3.27IleAsp: 3.27 ± 0.056	2.636IleGlu: 2.636 ± 0.056	1.175IlePhe: 1.175 ± 0.032	4.37IleGly: 4.37 ± 0.074	0.743IleHis: 0.743 ± 0.028	1.591IleIle: 1.591 ± 0.043	0.977IleLys: 0.977 ± 0.03	3.264IleLeu: 3.264 ± 0.061	0.601IleMet: 0.601 ± 0.023	1.04IleAsn: 1.04 ± 0.033	2.243IlePro: 2.243 ± 0.048	1.035IleGln: 1.035 ± 0.03	2.419IleArg: 2.419 ± 0.048	2.417IleSer: 2.417 ± 0.051	2.912IleThr: 2.912 ± 0.055	3.964IleVal: 3.964 ± 0.068	0.504IleTrp: 0.504 ± 0.021	0.821IleTyr: 0.821 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.989LysAla: 2.989 ± 0.067	0.101LysCys: 0.101 ± 0.01	1.475LysAsp: 1.475 ± 0.038	1.105LysGlu: 1.105 ± 0.036	0.617LysPhe: 0.617 ± 0.022	1.82LysGly: 1.82 ± 0.05	0.497LysHis: 0.497 ± 0.021	1.037LysIle: 1.037 ± 0.03	0.872LysLys: 0.872 ± 0.04	2.047LysLeu: 2.047 ± 0.044	0.44LysMet: 0.44 ± 0.021	0.607LysAsn: 0.607 ± 0.025	1.365LysPro: 1.365 ± 0.049	0.856LysGln: 0.856 ± 0.03	1.376LysArg: 1.376 ± 0.036	1.326LysSer: 1.326 ± 0.037	1.512LysThr: 1.512 ± 0.043	2.229LysVal: 2.229 ± 0.058	0.281LysTrp: 0.281 ± 0.016	0.581LysTyr: 0.581 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	14.07LeuAla: 14.07 ± 0.159	0.654LeuCys: 0.654 ± 0.024	6.48LeuAsp: 6.48 ± 0.093	4.496LeuGlu: 4.496 ± 0.071	2.614LeuPhe: 2.614 ± 0.053	8.824LeuGly: 8.824 ± 0.11	2.064LeuHis: 2.064 ± 0.045	4.564LeuIle: 4.564 ± 0.074	1.994LeuLys: 1.994 ± 0.052	10.381LeuLeu: 10.381 ± 0.136	1.77LeuMet: 1.77 ± 0.038	1.956LeuAsn: 1.956 ± 0.048	6.0LeuPro: 6.0 ± 0.073	2.96LeuGln: 2.96 ± 0.053	7.488LeuArg: 7.488 ± 0.106	5.893LeuSer: 5.893 ± 0.069	6.782LeuThr: 6.782 ± 0.075	8.954LeuVal: 8.954 ± 0.106	1.344LeuTrp: 1.344 ± 0.039	1.507LeuTyr: 1.507 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.366MetAla: 2.366 ± 0.051	0.148MetCys: 0.148 ± 0.011	0.908MetAsp: 0.908 ± 0.03	0.705MetGlu: 0.705 ± 0.026	0.519MetPhe: 0.519 ± 0.019	1.427MetGly: 1.427 ± 0.034	0.362MetHis: 0.362 ± 0.017	0.862MetIle: 0.862 ± 0.029	0.491MetLys: 0.491 ± 0.02	1.809MetLeu: 1.809 ± 0.039	0.401MetMet: 0.401 ± 0.02	0.489MetAsn: 0.489 ± 0.02	1.056MetPro: 1.056 ± 0.026	0.549MetGln: 0.549 ± 0.021	1.337MetArg: 1.337 ± 0.034	1.607MetSer: 1.607 ± 0.036	1.771MetThr: 1.771 ± 0.038	1.57MetVal: 1.57 ± 0.039	0.238MetTrp: 0.238 ± 0.015	0.285MetTyr: 0.285 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.558AsnAla: 2.558 ± 0.053	0.158AsnCys: 0.158 ± 0.013	1.231AsnAsp: 1.231 ± 0.034	0.901AsnGlu: 0.901 ± 0.028	0.611AsnPhe: 0.611 ± 0.025	1.934AsnGly: 1.934 ± 0.049	0.419AsnHis: 0.419 ± 0.018	0.764AsnIle: 0.764 ± 0.028	0.527AsnLys: 0.527 ± 0.024	2.172AsnLeu: 2.172 ± 0.049	0.323AsnMet: 0.323 ± 0.017	0.556AsnAsn: 0.556 ± 0.024	1.715AsnPro: 1.715 ± 0.046	0.686AsnGln: 0.686 ± 0.028	1.242AsnArg: 1.242 ± 0.037	1.102AsnSer: 1.102 ± 0.034	1.236AsnThr: 1.236 ± 0.037	1.765AsnVal: 1.765 ± 0.042	0.403AsnTrp: 0.403 ± 0.021	0.487AsnTyr: 0.487 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	7.254ProAla: 7.254 ± 0.107	0.237ProCys: 0.237 ± 0.017	4.284ProAsp: 4.284 ± 0.063	3.373ProGlu: 3.373 ± 0.059	1.593ProPhe: 1.593 ± 0.035	5.259ProGly: 5.259 ± 0.081	1.123ProHis: 1.123 ± 0.032	2.186ProIle: 2.186 ± 0.041	1.223ProLys: 1.223 ± 0.035	4.626ProLeu: 4.626 ± 0.063	1.031ProMet: 1.031 ± 0.03	1.073ProAsn: 1.073 ± 0.035	2.641ProPro: 2.641 ± 0.062	2.044ProGln: 2.044 ± 0.055	3.066ProArg: 3.066 ± 0.05	3.242ProSer: 3.242 ± 0.058	3.582ProThr: 3.582 ± 0.067	5.215ProVal: 5.215 ± 0.076	0.956ProTrp: 0.956 ± 0.029	1.185ProTyr: 1.185 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	4.009GlnAla: 4.009 ± 0.059	0.21GlnCys: 0.21 ± 0.013	1.723GlnAsp: 1.723 ± 0.039	1.668GlnGlu: 1.668 ± 0.045	1.006GlnPhe: 1.006 ± 0.031	2.153GlnGly: 2.153 ± 0.048	0.904GlnHis: 0.904 ± 0.032	1.795GlnIle: 1.795 ± 0.038	0.729GlnLys: 0.729 ± 0.03	3.55GlnLeu: 3.55 ± 0.057	0.668GlnMet: 0.668 ± 0.023	0.614GlnAsn: 0.614 ± 0.025	2.0GlnPro: 2.0 ± 0.045	1.697GlnGln: 1.697 ± 0.045	2.9GlnArg: 2.9 ± 0.054	1.744GlnSer: 1.744 ± 0.04	1.855GlnThr: 1.855 ± 0.041	3.366GlnVal: 3.366 ± 0.059	0.651GlnTrp: 0.651 ± 0.025	0.701GlnTyr: 0.701 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.895ArgAla: 7.895 ± 0.106	0.479ArgCys: 0.479 ± 0.02	4.264ArgAsp: 4.264 ± 0.071	3.829ArgGlu: 3.829 ± 0.069	2.182ArgPhe: 2.182 ± 0.046	4.941ArgGly: 4.941 ± 0.066	1.563ArgHis: 1.563 ± 0.042	3.185ArgIle: 3.185 ± 0.058	1.457ArgLys: 1.457 ± 0.033	7.042ArgLeu: 7.042 ± 0.098	1.596ArgMet: 1.596 ± 0.04	1.381ArgAsn: 1.381 ± 0.036	3.659ArgPro: 3.659 ± 0.061	2.271ArgGln: 2.271 ± 0.045	6.042ArgArg: 6.042 ± 0.103	4.312ArgSer: 4.312 ± 0.066	4.333ArgThr: 4.333 ± 0.065	5.35ArgVal: 5.35 ± 0.077	1.353ArgTrp: 1.353 ± 0.035	1.619ArgTyr: 1.619 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.369SerAla: 7.369 ± 0.087	0.369SerCys: 0.369 ± 0.016	3.377SerAsp: 3.377 ± 0.054	2.468SerGlu: 2.468 ± 0.05	1.81SerPhe: 1.81 ± 0.046	5.982SerGly: 5.982 ± 0.084	1.049SerHis: 1.049 ± 0.027	2.282SerIle: 2.282 ± 0.046	1.238SerLys: 1.238 ± 0.039	5.43SerLeu: 5.43 ± 0.066	1.354SerMet: 1.354 ± 0.035	1.25SerAsn: 1.25 ± 0.037	3.053SerPro: 3.053 ± 0.052	1.768SerGln: 1.768 ± 0.041	3.623SerArg: 3.623 ± 0.065	3.696SerSer: 3.696 ± 0.075	3.849SerThr: 3.849 ± 0.074	4.93SerVal: 4.93 ± 0.072	1.006SerTrp: 1.006 ± 0.033	1.327SerTyr: 1.327 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	8.001ThrAla: 8.001 ± 0.091	0.437ThrCys: 0.437 ± 0.021	3.969ThrAsp: 3.969 ± 0.063	2.676ThrGlu: 2.676 ± 0.051	1.912ThrPhe: 1.912 ± 0.046	6.216ThrGly: 6.216 ± 0.097	1.254ThrHis: 1.254 ± 0.034	2.725ThrIle: 2.725 ± 0.052	1.522ThrLys: 1.522 ± 0.041	5.99ThrLeu: 5.99 ± 0.079	1.169ThrMet: 1.169 ± 0.032	1.393ThrAsn: 1.393 ± 0.033	3.995ThrPro: 3.995 ± 0.072	1.924ThrGln: 1.924 ± 0.04	3.643ThrArg: 3.643 ± 0.06	3.813ThrSer: 3.813 ± 0.08	4.302ThrThr: 4.302 ± 0.082	5.883ThrVal: 5.883 ± 0.086	1.084ThrTrp: 1.084 ± 0.029	1.553ThrTyr: 1.553 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	11.713ValAla: 11.713 ± 0.118	0.672ValCys: 0.672 ± 0.026	5.697ValAsp: 5.697 ± 0.071	4.479ValGlu: 4.479 ± 0.085	2.463ValPhe: 2.463 ± 0.051	7.155ValGly: 7.155 ± 0.095	1.758ValHis: 1.758 ± 0.036	4.047ValIle: 4.047 ± 0.064	1.765ValLys: 1.765 ± 0.041	9.432ValLeu: 9.432 ± 0.118	1.566ValMet: 1.566 ± 0.044	1.807ValAsn: 1.807 ± 0.04	4.839ValPro: 4.839 ± 0.066	2.669ValGln: 2.669 ± 0.044	6.237ValArg: 6.237 ± 0.088	5.042ValSer: 5.042 ± 0.074	6.225ValThr: 6.225 ± 0.104	8.794ValVal: 8.794 ± 0.105	1.145ValTrp: 1.145 ± 0.029	1.454ValTyr: 1.454 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.768TrpAla: 1.768 ± 0.041	0.18TrpCys: 0.18 ± 0.012	0.85TrpAsp: 0.85 ± 0.029	0.631TrpGlu: 0.631 ± 0.023	0.574TrpPhe: 0.574 ± 0.024	1.132TrpGly: 1.132 ± 0.034	0.386TrpHis: 0.386 ± 0.019	0.732TrpIle: 0.732 ± 0.024	0.353TrpLys: 0.353 ± 0.018	1.93TrpLeu: 1.93 ± 0.046	0.352TrpMet: 0.352 ± 0.019	0.391TrpAsn: 0.391 ± 0.02	0.859TrpPro: 0.859 ± 0.03	0.709TrpGln: 0.709 ± 0.026	1.271TrpArg: 1.271 ± 0.035	1.145TrpSer: 1.145 ± 0.032	1.007TrpThr: 1.007 ± 0.032	1.225TrpVal: 1.225 ± 0.034	0.438TrpTrp: 0.438 ± 0.02	0.307TrpTyr: 0.307 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.623TyrAla: 2.623 ± 0.049	0.181TyrCys: 0.181 ± 0.014	1.587TyrAsp: 1.587 ± 0.04	1.077TyrGlu: 1.077 ± 0.032	0.7TyrPhe: 0.7 ± 0.023	2.023TyrGly: 2.023 ± 0.048	0.366TyrHis: 0.366 ± 0.021	0.585TyrIle: 0.585 ± 0.025	0.386TyrLys: 0.386 ± 0.021	2.378TyrLeu: 2.378 ± 0.049	0.227TyrMet: 0.227 ± 0.015	0.461TyrAsn: 0.461 ± 0.022	1.143TyrPro: 1.143 ± 0.033	0.667TyrGln: 0.667 ± 0.022	1.565TyrArg: 1.565 ± 0.042	1.077TyrSer: 1.077 ± 0.034	1.145TyrThr: 1.145 ± 0.033	1.859TyrVal: 1.859 ± 0.043	0.363TyrTrp: 0.363 ± 0.02	0.478TyrTyr: 0.478 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3548 proteins (1140667 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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