Amino acid dipepetide frequency for Bovine enteric calicivirus Newbury agent-1 (isolate Bovine/UK/Newbury1/1976) (BEC)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.736AlaAla: 12.736 ± 0.285
0.822AlaCys: 0.822 ± 0.373
4.519AlaAsp: 4.519 ± 0.03
3.698AlaGlu: 3.698 ± 1.68
2.054AlaPhe: 2.054 ± 0.933
9.449AlaGly: 9.449 ± 1.778
1.233AlaHis: 1.233 ± 0.56
4.519AlaIle: 4.519 ± 0.03
2.465AlaLys: 2.465 ± 0.904
9.449AlaLeu: 9.449 ± 0.246
3.287AlaMet: 3.287 ± 0.53
3.287AlaAsn: 3.287 ± 0.53
6.574AlaPro: 6.574 ± 2.986
2.876AlaGln: 2.876 ± 2.741
6.574AlaArg: 6.574 ± 3.084
7.395AlaSer: 7.395 ± 2.711
6.163AlaThr: 6.163 ± 1.247
4.519AlaVal: 4.519 ± 2.053
2.054AlaTrp: 2.054 ± 0.933
2.876AlaTyr: 2.876 ± 1.307
0.0AlaXaa: 0.0 ± 0.0
Cys
0.822CysAla: 0.822 ± 0.373
0.0CysCys: 0.0 ± 0.0
0.411CysAsp: 0.411 ± 0.187
0.411CysGlu: 0.411 ± 0.187
0.411CysPhe: 0.411 ± 0.187
1.643CysGly: 1.643 ± 0.747
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.822CysLys: 0.822 ± 0.373
0.411CysLeu: 0.411 ± 0.187
0.411CysMet: 0.411 ± 0.187
1.233CysAsn: 1.233 ± 0.56
0.822CysPro: 0.822 ± 0.373
0.411CysGln: 0.411 ± 0.187
0.411CysArg: 0.411 ± 0.187
1.643CysSer: 1.643 ± 0.747
1.233CysThr: 1.233 ± 0.56
0.822CysVal: 0.822 ± 0.373
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.519AspAla: 4.519 ± 1.994
1.233AspCys: 1.233 ± 0.56
2.876AspAsp: 2.876 ± 1.307
3.287AspGlu: 3.287 ± 1.493
1.643AspPhe: 1.643 ± 0.747
3.287AspGly: 3.287 ± 1.493
2.054AspHis: 2.054 ± 0.933
3.287AspIle: 3.287 ± 0.53
2.465AspLys: 2.465 ± 1.12
5.752AspLeu: 5.752 ± 2.613
1.233AspMet: 1.233 ± 1.464
1.643AspAsn: 1.643 ± 1.277
5.341AspPro: 5.341 ± 0.403
0.822AspGln: 0.822 ± 0.373
2.054AspArg: 2.054 ± 1.09
1.233AspSer: 1.233 ± 0.56
3.287AspThr: 3.287 ± 1.493
2.876AspVal: 2.876 ± 1.307
0.822AspTrp: 0.822 ± 0.373
1.233AspTyr: 1.233 ± 0.56
0.0AspXaa: 0.0 ± 0.0
Glu
3.698GluAla: 3.698 ± 0.344
0.822GluCys: 0.822 ± 0.373
3.287GluAsp: 3.287 ± 1.493
2.465GluGlu: 2.465 ± 1.12
0.822GluPhe: 0.822 ± 0.373
3.698GluGly: 3.698 ± 1.68
0.822GluHis: 0.822 ± 0.373
1.233GluIle: 1.233 ± 0.56
0.822GluLys: 0.822 ± 0.373
6.163GluLeu: 6.163 ± 3.271
0.411GluMet: 0.411 ± 0.187
1.233GluAsn: 1.233 ± 1.464
1.643GluPro: 1.643 ± 0.747
2.054GluGln: 2.054 ± 5.137
1.643GluArg: 1.643 ± 0.747
2.054GluSer: 2.054 ± 0.933
1.643GluThr: 1.643 ± 0.747
2.876GluVal: 2.876 ± 1.307
0.822GluTrp: 0.822 ± 0.373
1.643GluTyr: 1.643 ± 0.747
0.0GluXaa: 0.0 ± 0.0
Phe
2.876PheAla: 2.876 ± 0.717
0.0PheCys: 0.0 ± 0.0
2.054PheAsp: 2.054 ± 0.933
0.411PheGlu: 0.411 ± 0.187
1.643PhePhe: 1.643 ± 0.747
2.876PheGly: 2.876 ± 2.741
0.0PheHis: 0.0 ± 0.0
0.822PheIle: 0.822 ± 0.373
2.465PheLys: 2.465 ± 1.12
2.876PheLeu: 2.876 ± 0.717
0.411PheMet: 0.411 ± 0.187
1.643PheAsn: 1.643 ± 0.747
1.643PhePro: 1.643 ± 0.747
0.411PheGln: 0.411 ± 0.187
0.822PheArg: 0.822 ± 0.373
2.465PheSer: 2.465 ± 2.927
2.876PheThr: 2.876 ± 1.307
2.465PheVal: 2.465 ± 1.12
0.822PheTrp: 0.822 ± 0.373
0.411PheTyr: 0.411 ± 0.187
0.0PheXaa: 0.0 ± 0.0
Gly
6.163GlyAla: 6.163 ± 3.271
0.822GlyCys: 0.822 ± 0.373
3.698GlyAsp: 3.698 ± 0.344
2.054GlyGlu: 2.054 ± 1.09
2.876GlyPhe: 2.876 ± 1.307
6.574GlyGly: 6.574 ± 1.061
2.054GlyHis: 2.054 ± 0.933
4.108GlyIle: 4.108 ± 0.157
2.876GlyLys: 2.876 ± 0.717
9.449GlyLeu: 9.449 ± 5.825
2.876GlyMet: 2.876 ± 1.307
2.876GlyAsn: 2.876 ± 1.307
7.395GlyPro: 7.395 ± 1.336
2.876GlyGln: 2.876 ± 1.307
3.287GlyArg: 3.287 ± 1.493
5.341GlySer: 5.341 ± 7.691
7.395GlyThr: 7.395 ± 3.36
6.574GlyVal: 6.574 ± 2.986
2.465GlyTrp: 2.465 ± 1.12
1.643GlyTyr: 1.643 ± 0.747
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.411HisCys: 0.411 ± 0.187
1.233HisAsp: 1.233 ± 0.56
0.822HisGlu: 0.822 ± 0.373
0.822HisPhe: 0.822 ± 1.65
0.822HisGly: 0.822 ± 0.373
0.822HisHis: 0.822 ± 0.373
2.054HisIle: 2.054 ± 0.933
1.643HisLys: 1.643 ± 0.747
2.876HisLeu: 2.876 ± 1.307
0.0HisMet: 0.0 ± 0.0
1.643HisAsn: 1.643 ± 0.747
2.054HisPro: 2.054 ± 0.933
2.465HisGln: 2.465 ± 0.904
2.054HisArg: 2.054 ± 0.933
0.822HisSer: 0.822 ± 0.373
1.233HisThr: 1.233 ± 0.56
2.054HisVal: 2.054 ± 0.933
0.822HisTrp: 0.822 ± 0.373
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.93IleAla: 4.93 ± 1.807
0.0IleCys: 0.0 ± 0.0
2.054IleAsp: 2.054 ± 0.933
1.233IleGlu: 1.233 ± 0.56
0.411IlePhe: 0.411 ± 0.187
2.876IleGly: 2.876 ± 1.307
0.822IleHis: 0.822 ± 0.373
3.698IleIle: 3.698 ± 1.68
3.287IleLys: 3.287 ± 0.53
3.287IleLeu: 3.287 ± 1.493
0.822IleMet: 0.822 ± 0.373
5.341IleAsn: 5.341 ± 0.403
3.698IlePro: 3.698 ± 1.68
2.054IleGln: 2.054 ± 0.933
3.287IleArg: 3.287 ± 4.578
2.465IleSer: 2.465 ± 6.974
4.108IleThr: 4.108 ± 1.866
2.465IleVal: 2.465 ± 0.904
1.233IleTrp: 1.233 ± 0.56
0.411IleTyr: 0.411 ± 0.187
0.0IleXaa: 0.0 ± 0.0
Lys
1.643LysAla: 1.643 ± 0.747
0.822LysCys: 0.822 ± 0.373
1.233LysAsp: 1.233 ± 0.56
1.233LysGlu: 1.233 ± 3.487
0.411LysPhe: 0.411 ± 0.187
3.698LysGly: 3.698 ± 1.68
1.233LysHis: 1.233 ± 1.464
2.054LysIle: 2.054 ± 0.933
2.465LysLys: 2.465 ± 1.12
2.465LysLeu: 2.465 ± 1.12
0.822LysMet: 0.822 ± 0.373
0.411LysAsn: 0.411 ± 0.187
0.822LysPro: 0.822 ± 0.373
1.233LysGln: 1.233 ± 1.464
3.287LysArg: 3.287 ± 1.493
5.752LysSer: 5.752 ± 0.589
2.054LysThr: 2.054 ± 0.933
2.876LysVal: 2.876 ± 1.307
0.411LysTrp: 0.411 ± 0.187
2.054LysTyr: 2.054 ± 0.933
0.0LysXaa: 0.0 ± 0.0
Leu
11.915LeuAla: 11.915 ± 1.366
1.643LeuCys: 1.643 ± 0.747
2.876LeuAsp: 2.876 ± 0.717
3.698LeuGlu: 3.698 ± 1.68
2.465LeuPhe: 2.465 ± 0.904
7.395LeuGly: 7.395 ± 4.735
1.643LeuHis: 1.643 ± 0.747
3.698LeuIle: 3.698 ± 1.68
3.698LeuLys: 3.698 ± 1.68
5.341LeuLeu: 5.341 ± 0.403
1.233LeuMet: 1.233 ± 1.392
2.465LeuAsn: 2.465 ± 2.927
6.984LeuPro: 6.984 ± 3.173
2.054LeuGln: 2.054 ± 3.114
4.519LeuArg: 4.519 ± 1.994
9.86LeuSer: 9.86 ± 7.662
7.806LeuThr: 7.806 ± 0.501
6.163LeuVal: 6.163 ± 2.8
0.822LeuTrp: 0.822 ± 0.373
1.643LeuTyr: 1.643 ± 0.747
0.0LeuXaa: 0.0 ± 0.0
Met
2.054MetAla: 2.054 ± 1.09
0.411MetCys: 0.411 ± 0.187
0.822MetAsp: 0.822 ± 0.373
0.822MetGlu: 0.822 ± 1.65
0.822MetPhe: 0.822 ± 0.373
2.876MetGly: 2.876 ± 0.717
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.411MetLys: 0.411 ± 0.187
2.465MetLeu: 2.465 ± 2.927
0.411MetMet: 0.411 ± 1.837
0.411MetAsn: 0.411 ± 0.187
2.465MetPro: 2.465 ± 1.12
0.411MetGln: 0.411 ± 0.187
1.233MetArg: 1.233 ± 0.56
1.233MetSer: 1.233 ± 0.56
0.411MetThr: 0.411 ± 0.187
2.465MetVal: 2.465 ± 1.12
0.411MetTrp: 0.411 ± 0.187
0.822MetTyr: 0.822 ± 0.373
0.0MetXaa: 0.0 ± 0.0
Asn
3.287AsnAla: 3.287 ± 1.493
0.822AsnCys: 0.822 ± 0.373
2.876AsnAsp: 2.876 ± 1.307
2.054AsnGlu: 2.054 ± 0.933
1.643AsnPhe: 1.643 ± 1.277
2.465AsnGly: 2.465 ± 1.12
1.233AsnHis: 1.233 ± 1.464
2.054AsnIle: 2.054 ± 0.933
1.233AsnLys: 1.233 ± 0.56
1.233AsnLeu: 1.233 ± 1.464
1.233AsnMet: 1.233 ± 1.464
1.643AsnAsn: 1.643 ± 1.277
6.574AsnPro: 6.574 ± 3.084
0.822AsnGln: 0.822 ± 0.373
1.233AsnArg: 1.233 ± 1.464
4.108AsnSer: 4.108 ± 2.181
2.465AsnThr: 2.465 ± 0.904
2.054AsnVal: 2.054 ± 0.933
0.411AsnTrp: 0.411 ± 1.837
1.233AsnTyr: 1.233 ± 1.464
0.0AsnXaa: 0.0 ± 0.0
Pro
7.395ProAla: 7.395 ± 3.36
0.411ProCys: 0.411 ± 0.187
5.752ProAsp: 5.752 ± 0.589
3.287ProGlu: 3.287 ± 1.493
2.465ProPhe: 2.465 ± 0.904
6.163ProGly: 6.163 ± 2.8
2.465ProHis: 2.465 ± 1.12
3.287ProIle: 3.287 ± 2.554
2.465ProLys: 2.465 ± 0.904
4.519ProLeu: 4.519 ± 2.053
1.233ProMet: 1.233 ± 0.56
3.698ProAsn: 3.698 ± 2.367
4.519ProPro: 4.519 ± 0.03
3.287ProGln: 3.287 ± 1.493
2.465ProArg: 2.465 ± 1.12
7.395ProSer: 7.395 ± 0.688
3.698ProThr: 3.698 ± 1.68
5.752ProVal: 5.752 ± 2.613
0.0ProTrp: 0.0 ± 0.0
1.643ProTyr: 1.643 ± 0.747
0.0ProXaa: 0.0 ± 0.0
Gln
2.054GlnAla: 2.054 ± 3.114
0.0GlnCys: 0.0 ± 0.0
1.233GlnAsp: 1.233 ± 0.56
1.233GlnGlu: 1.233 ± 0.56
0.822GlnPhe: 0.822 ± 0.373
3.287GlnGly: 3.287 ± 1.493
1.643GlnHis: 1.643 ± 0.747
1.643GlnIle: 1.643 ± 3.301
0.822GlnLys: 0.822 ± 1.65
4.519GlnLeu: 4.519 ± 0.03
0.0GlnMet: 0.0 ± 0.0
0.411GlnAsn: 0.411 ± 0.187
2.876GlnPro: 2.876 ± 0.717
1.643GlnGln: 1.643 ± 5.324
2.465GlnArg: 2.465 ± 0.904
2.876GlnSer: 2.876 ± 0.717
2.054GlnThr: 2.054 ± 0.933
2.465GlnVal: 2.465 ± 1.12
0.822GlnTrp: 0.822 ± 0.373
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.93ArgAla: 4.93 ± 1.807
1.643ArgCys: 1.643 ± 0.747
2.465ArgAsp: 2.465 ± 0.904
3.287ArgGlu: 3.287 ± 1.493
2.465ArgPhe: 2.465 ± 1.12
3.287ArgGly: 3.287 ± 1.493
2.465ArgHis: 2.465 ± 1.12
1.643ArgIle: 1.643 ± 1.277
0.822ArgLys: 0.822 ± 0.373
5.341ArgLeu: 5.341 ± 1.621
1.233ArgMet: 1.233 ± 0.56
3.287ArgAsn: 3.287 ± 2.554
3.287ArgPro: 3.287 ± 2.554
1.643ArgGln: 1.643 ± 0.747
2.876ArgArg: 2.876 ± 1.307
2.876ArgSer: 2.876 ± 6.788
3.698ArgThr: 3.698 ± 0.344
4.93ArgVal: 4.93 ± 2.24
1.233ArgTrp: 1.233 ± 1.464
0.822ArgTyr: 0.822 ± 0.373
0.0ArgXaa: 0.0 ± 0.0
Ser
6.984SerAla: 6.984 ± 0.874
0.822SerCys: 0.822 ± 0.373
4.519SerAsp: 4.519 ± 0.03
1.643SerGlu: 1.643 ± 3.301
1.643SerPhe: 1.643 ± 0.747
7.806SerGly: 7.806 ± 4.548
1.233SerHis: 1.233 ± 0.56
4.93SerIle: 4.93 ± 5.855
2.876SerLys: 2.876 ± 1.307
8.217SerLeu: 8.217 ± 6.385
1.233SerMet: 1.233 ± 0.56
2.054SerAsn: 2.054 ± 5.137
3.698SerPro: 3.698 ± 1.68
2.054SerGln: 2.054 ± 0.933
4.108SerArg: 4.108 ± 2.181
6.984SerSer: 6.984 ± 8.968
5.752SerThr: 5.752 ± 1.434
9.86SerVal: 9.86 ± 9.686
0.822SerTrp: 0.822 ± 0.373
1.233SerTyr: 1.233 ± 0.56
0.0SerXaa: 0.0 ± 0.0
Thr
8.217ThrAla: 8.217 ± 0.314
0.411ThrCys: 0.411 ± 0.187
1.643ThrAsp: 1.643 ± 0.747
3.287ThrGlu: 3.287 ± 0.53
2.465ThrPhe: 2.465 ± 0.904
4.519ThrGly: 4.519 ± 0.03
2.054ThrHis: 2.054 ± 0.933
3.287ThrIle: 3.287 ± 1.493
1.643ThrLys: 1.643 ± 0.747
5.341ThrLeu: 5.341 ± 0.403
1.233ThrMet: 1.233 ± 0.56
2.054ThrAsn: 2.054 ± 0.933
5.752ThrPro: 5.752 ± 0.589
1.643ThrGln: 1.643 ± 0.747
4.93ThrArg: 4.93 ± 2.24
6.574ThrSer: 6.574 ± 0.963
4.519ThrThr: 4.519 ± 0.03
4.519ThrVal: 4.519 ± 0.03
2.465ThrTrp: 2.465 ± 1.12
2.465ThrTyr: 2.465 ± 1.12
0.0ThrXaa: 0.0 ± 0.0
Val
9.86ValAla: 9.86 ± 4.479
0.0ValCys: 0.0 ± 0.0
2.465ValAsp: 2.465 ± 1.12
3.698ValGlu: 3.698 ± 1.68
3.287ValPhe: 3.287 ± 0.53
6.574ValGly: 6.574 ± 1.061
1.233ValHis: 1.233 ± 0.56
4.519ValIle: 4.519 ± 2.053
3.287ValLys: 3.287 ± 1.493
6.574ValLeu: 6.574 ± 2.986
1.643ValMet: 1.643 ± 0.373
2.465ValAsn: 2.465 ± 1.12
5.752ValPro: 5.752 ± 2.613
2.465ValGln: 2.465 ± 1.12
4.108ValArg: 4.108 ± 4.204
4.108ValSer: 4.108 ± 0.157
4.519ValThr: 4.519 ± 0.03
7.806ValVal: 7.806 ± 3.546
2.465ValTrp: 2.465 ± 1.12
2.054ValTyr: 2.054 ± 0.933
0.0ValXaa: 0.0 ± 0.0
Trp
1.643TrpAla: 1.643 ± 0.747
0.411TrpCys: 0.411 ± 0.187
2.876TrpAsp: 2.876 ± 0.717
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.233TrpGly: 1.233 ± 1.464
0.411TrpHis: 0.411 ± 0.187
0.411TrpIle: 0.411 ± 0.187
0.0TrpLys: 0.0 ± 0.0
1.643TrpLeu: 1.643 ± 0.747
0.411TrpMet: 0.411 ± 0.187
1.643TrpAsn: 1.643 ± 0.747
0.0TrpPro: 0.0 ± 0.0
0.822TrpGln: 0.822 ± 0.373
2.054TrpArg: 2.054 ± 0.933
1.643TrpSer: 1.643 ± 0.747
1.233TrpThr: 1.233 ± 0.56
2.054TrpVal: 2.054 ± 0.933
0.0TrpTrp: 0.0 ± 0.0
0.411TrpTyr: 0.411 ± 0.187
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.822TyrAla: 0.822 ± 0.373
0.411TyrCys: 0.411 ± 0.187
2.054TyrAsp: 2.054 ± 0.933
1.233TyrGlu: 1.233 ± 1.464
0.822TyrPhe: 0.822 ± 0.373
2.876TyrGly: 2.876 ± 1.307
1.233TyrHis: 1.233 ± 0.56
1.233TyrIle: 1.233 ± 0.56
0.411TyrLys: 0.411 ± 0.187
0.411TyrLeu: 0.411 ± 0.187
0.411TyrMet: 0.411 ± 0.187
1.233TyrAsn: 1.233 ± 0.56
0.0TyrPro: 0.0 ± 0.0
0.822TyrGln: 0.822 ± 0.373
0.822TyrArg: 0.822 ± 0.373
1.643TyrSer: 1.643 ± 0.747
2.876TyrThr: 2.876 ± 1.307
3.287TyrVal: 3.287 ± 1.493
0.0TyrTrp: 0.0 ± 0.0
0.822TyrTyr: 0.822 ± 0.373
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2435 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski