Amino acid dipepetide frequency for Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum gypseum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.617AlaAla: 8.617 ± 0.072	1.033AlaCys: 1.033 ± 0.018	4.042AlaAsp: 4.042 ± 0.032	5.034AlaGlu: 5.034 ± 0.037	2.899AlaPhe: 2.899 ± 0.029	5.612AlaGly: 5.612 ± 0.047	1.686AlaHis: 1.686 ± 0.023	4.303AlaIle: 4.303 ± 0.032	4.091AlaLys: 4.091 ± 0.032	7.27AlaLeu: 7.27 ± 0.054	1.847AlaMet: 1.847 ± 0.024	2.849AlaAsn: 2.849 ± 0.026	4.441AlaPro: 4.441 ± 0.047	3.164AlaGln: 3.164 ± 0.033	4.687AlaArg: 4.687 ± 0.037	7.266AlaSer: 7.266 ± 0.043	5.008AlaThr: 5.008 ± 0.034	5.123AlaVal: 5.123 ± 0.033	1.017AlaTrp: 1.017 ± 0.016	2.021AlaTyr: 2.021 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.892CysAla: 0.892 ± 0.017	0.28CysCys: 0.28 ± 0.011	0.642CysAsp: 0.642 ± 0.014	0.63CysGlu: 0.63 ± 0.014	0.535CysPhe: 0.535 ± 0.011	0.958CysGly: 0.958 ± 0.018	0.348CysHis: 0.348 ± 0.011	0.754CysIle: 0.754 ± 0.016	0.557CysLys: 0.557 ± 0.014	1.325CysLeu: 1.325 ± 0.02	0.286CysMet: 0.286 ± 0.009	0.434CysAsn: 0.434 ± 0.009	0.715CysPro: 0.715 ± 0.016	0.465CysGln: 0.465 ± 0.011	0.804CysArg: 0.804 ± 0.014	1.004CysSer: 1.004 ± 0.018	0.669CysThr: 0.669 ± 0.014	0.768CysVal: 0.768 ± 0.014	0.183CysTrp: 0.183 ± 0.007	0.381CysTyr: 0.381 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.308AspAla: 4.308 ± 0.036	0.642AspCys: 0.642 ± 0.014	4.099AspAsp: 4.099 ± 0.047	4.532AspGlu: 4.532 ± 0.044	2.071AspPhe: 2.071 ± 0.023	4.01AspGly: 4.01 ± 0.035	1.19AspHis: 1.19 ± 0.02	3.452AspIle: 3.452 ± 0.03	2.583AspLys: 2.583 ± 0.026	4.764AspLeu: 4.764 ± 0.036	1.271AspMet: 1.271 ± 0.018	2.006AspAsn: 2.006 ± 0.021	3.124AspPro: 3.124 ± 0.029	1.823AspGln: 1.823 ± 0.021	3.032AspArg: 3.032 ± 0.031	4.296AspSer: 4.296 ± 0.035	3.116AspThr: 3.116 ± 0.025	3.339AspVal: 3.339 ± 0.03	0.785AspTrp: 0.785 ± 0.012	1.514AspTyr: 1.514 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.221GluAla: 5.221 ± 0.044	0.666GluCys: 0.666 ± 0.013	4.224GluAsp: 4.224 ± 0.041	5.73GluGlu: 5.73 ± 0.066	1.961GluPhe: 1.961 ± 0.026	3.643GluGly: 3.643 ± 0.031	1.345GluHis: 1.345 ± 0.017	3.221GluIle: 3.221 ± 0.032	4.083GluLys: 4.083 ± 0.043	5.248GluLeu: 5.248 ± 0.038	1.454GluMet: 1.454 ± 0.017	2.472GluAsn: 2.472 ± 0.023	2.975GluPro: 2.975 ± 0.045	2.538GluGln: 2.538 ± 0.027	3.895GluArg: 3.895 ± 0.034	4.485GluSer: 4.485 ± 0.039	3.45GluThr: 3.45 ± 0.04	3.5GluVal: 3.5 ± 0.031	0.809GluTrp: 0.809 ± 0.014	1.76GluTyr: 1.76 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	2.77PheAla: 2.77 ± 0.029	0.567PheCys: 0.567 ± 0.012	2.222PheAsp: 2.222 ± 0.023	2.069PheGlu: 2.069 ± 0.023	1.552PhePhe: 1.552 ± 0.022	2.641PheGly: 2.641 ± 0.03	0.91PheHis: 0.91 ± 0.016	1.92PheIle: 1.92 ± 0.022	1.581PheLys: 1.581 ± 0.021	3.356PheLeu: 3.356 ± 0.031	0.735PheMet: 0.735 ± 0.014	1.477PheAsn: 1.477 ± 0.021	1.929PhePro: 1.929 ± 0.021	1.341PheGln: 1.341 ± 0.018	1.956PheArg: 1.956 ± 0.026	3.179PheSer: 3.179 ± 0.029	2.159PheThr: 2.159 ± 0.025	2.207PheVal: 2.207 ± 0.028	0.573PheTrp: 0.573 ± 0.011	1.085PheTyr: 1.085 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	4.847GlyAla: 4.847 ± 0.041	0.899GlyCys: 0.899 ± 0.018	3.582GlyAsp: 3.582 ± 0.032	3.695GlyGlu: 3.695 ± 0.031	2.59GlyPhe: 2.59 ± 0.033	5.457GlyGly: 5.457 ± 0.062	1.662GlyHis: 1.662 ± 0.027	3.618GlyIle: 3.618 ± 0.041	3.66GlyLys: 3.66 ± 0.035	5.692GlyLeu: 5.692 ± 0.044	1.564GlyMet: 1.564 ± 0.022	2.545GlyAsn: 2.545 ± 0.024	3.243GlyPro: 3.243 ± 0.025	2.557GlyGln: 2.557 ± 0.026	4.125GlyArg: 4.125 ± 0.036	5.789GlySer: 5.789 ± 0.041	3.837GlyThr: 3.837 ± 0.031	4.131GlyVal: 4.131 ± 0.036	1.084GlyTrp: 1.084 ± 0.017	2.108GlyTyr: 2.108 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.75HisAla: 1.75 ± 0.02	0.326HisCys: 0.326 ± 0.01	1.286HisAsp: 1.286 ± 0.018	1.29HisGlu: 1.29 ± 0.018	0.887HisPhe: 0.887 ± 0.015	1.773HisGly: 1.773 ± 0.021	0.967HisHis: 0.967 ± 0.022	1.338HisIle: 1.338 ± 0.018	0.95HisLys: 0.95 ± 0.017	2.18HisLeu: 2.18 ± 0.024	0.48HisMet: 0.48 ± 0.011	0.896HisAsn: 0.896 ± 0.015	1.702HisPro: 1.702 ± 0.02	1.137HisGln: 1.137 ± 0.021	1.565HisArg: 1.565 ± 0.021	2.042HisSer: 2.042 ± 0.025	1.315HisThr: 1.315 ± 0.02	1.315HisVal: 1.315 ± 0.017	0.31HisTrp: 0.31 ± 0.009	0.684HisTyr: 0.684 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.987IleAla: 3.987 ± 0.031	0.819IleCys: 0.819 ± 0.014	3.018IleAsp: 3.018 ± 0.026	3.031IleGlu: 3.031 ± 0.031	2.086IlePhe: 2.086 ± 0.025	3.165IleGly: 3.165 ± 0.032	1.287IleHis: 1.287 ± 0.018	2.743IleIle: 2.743 ± 0.029	2.444IleLys: 2.444 ± 0.023	4.833IleLeu: 4.833 ± 0.046	1.039IleMet: 1.039 ± 0.017	1.961IleAsn: 1.961 ± 0.022	3.417IlePro: 3.417 ± 0.031	2.008IleGln: 2.008 ± 0.023	3.009IleArg: 3.009 ± 0.029	4.491IleSer: 4.491 ± 0.038	2.921IleThr: 2.921 ± 0.029	3.069IleVal: 3.069 ± 0.03	0.699IleTrp: 0.699 ± 0.014	1.506IleTyr: 1.506 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.343LysAla: 4.343 ± 0.045	0.569LysCys: 0.569 ± 0.014	2.957LysAsp: 2.957 ± 0.031	3.745LysGlu: 3.745 ± 0.039	1.559LysPhe: 1.559 ± 0.019	3.151LysGly: 3.151 ± 0.028	1.162LysHis: 1.162 ± 0.018	2.456LysIle: 2.456 ± 0.027	3.698LysLys: 3.698 ± 0.059	4.364LysLeu: 4.364 ± 0.039	1.094LysMet: 1.094 ± 0.017	1.904LysAsn: 1.904 ± 0.021	3.052LysPro: 3.052 ± 0.034	2.079LysGln: 2.079 ± 0.024	3.627LysArg: 3.627 ± 0.037	3.861LysSer: 3.861 ± 0.033	2.864LysThr: 2.864 ± 0.028	2.874LysVal: 2.874 ± 0.025	0.673LysTrp: 0.673 ± 0.012	1.5LysTyr: 1.5 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	7.516LeuAla: 7.516 ± 0.046	1.205LeuCys: 1.205 ± 0.017	5.053LeuAsp: 5.053 ± 0.033	5.555LeuGlu: 5.555 ± 0.041	3.323LeuPhe: 3.323 ± 0.035	5.592LeuGly: 5.592 ± 0.044	2.238LeuHis: 2.238 ± 0.025	4.049LeuIle: 4.049 ± 0.036	4.455LeuLys: 4.455 ± 0.038	8.485LeuLeu: 8.485 ± 0.074	1.704LeuMet: 1.704 ± 0.021	3.266LeuAsn: 3.266 ± 0.03	5.563LeuPro: 5.563 ± 0.046	3.782LeuGln: 3.782 ± 0.033	5.732LeuArg: 5.732 ± 0.042	7.58LeuSer: 7.58 ± 0.053	4.734LeuThr: 4.734 ± 0.033	5.185LeuVal: 5.185 ± 0.037	1.099LeuTrp: 1.099 ± 0.018	2.348LeuTyr: 2.348 ± 0.028	0.0LeuXaa: 0.0 ± 0.0
Met	2.228MetAla: 2.228 ± 0.021	0.23MetCys: 0.23 ± 0.007	1.282MetAsp: 1.282 ± 0.016	1.368MetGlu: 1.368 ± 0.019	0.742MetPhe: 0.742 ± 0.014	1.468MetGly: 1.468 ± 0.021	0.47MetHis: 0.47 ± 0.01	1.0MetIle: 1.0 ± 0.015	1.131MetLys: 1.131 ± 0.015	1.843MetLeu: 1.843 ± 0.021	0.539MetMet: 0.539 ± 0.012	0.824MetAsn: 0.824 ± 0.013	1.184MetPro: 1.184 ± 0.019	0.843MetGln: 0.843 ± 0.015	1.173MetArg: 1.173 ± 0.016	1.78MetSer: 1.78 ± 0.022	1.21MetThr: 1.21 ± 0.016	1.3MetVal: 1.3 ± 0.018	0.232MetTrp: 0.232 ± 0.008	0.496MetTyr: 0.496 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.028AsnAla: 3.028 ± 0.026	0.48AsnCys: 0.48 ± 0.013	2.003AsnAsp: 2.003 ± 0.025	2.137AsnGlu: 2.137 ± 0.024	1.369AsnPhe: 1.369 ± 0.018	3.012AsnGly: 3.012 ± 0.032	0.894AsnHis: 0.894 ± 0.015	2.307AsnIle: 2.307 ± 0.025	1.745AsnLys: 1.745 ± 0.022	3.26AsnLeu: 3.26 ± 0.028	0.873AsnMet: 0.873 ± 0.016	1.759AsnAsn: 1.759 ± 0.027	2.53AsnPro: 2.53 ± 0.027	1.399AsnGln: 1.399 ± 0.022	2.061AsnArg: 2.061 ± 0.023	3.056AsnSer: 3.056 ± 0.028	2.35AsnThr: 2.35 ± 0.027	2.216AsnVal: 2.216 ± 0.022	0.512AsnTrp: 0.512 ± 0.011	1.043AsnTyr: 1.043 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.197ProAla: 5.197 ± 0.048	0.583ProCys: 0.583 ± 0.014	3.188ProAsp: 3.188 ± 0.027	3.854ProGlu: 3.854 ± 0.041	2.066ProPhe: 2.066 ± 0.025	3.964ProGly: 3.964 ± 0.036	1.352ProHis: 1.352 ± 0.022	2.684ProIle: 2.684 ± 0.027	2.879ProLys: 2.879 ± 0.027	4.82ProLeu: 4.82 ± 0.038	1.066ProMet: 1.066 ± 0.018	2.264ProAsn: 2.264 ± 0.027	5.27ProPro: 5.27 ± 0.071	2.606ProGln: 2.606 ± 0.031	3.414ProArg: 3.414 ± 0.033	6.389ProSer: 6.389 ± 0.056	4.086ProThr: 4.086 ± 0.054	3.562ProVal: 3.562 ± 0.036	0.682ProTrp: 0.682 ± 0.012	1.5ProTyr: 1.5 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.349GlnAla: 3.349 ± 0.035	0.455GlnCys: 0.455 ± 0.012	1.975GlnAsp: 1.975 ± 0.022	2.417GlnGlu: 2.417 ± 0.024	1.314GlnPhe: 1.314 ± 0.02	2.422GlnGly: 2.422 ± 0.027	1.195GlnHis: 1.195 ± 0.021	1.849GlnIle: 1.849 ± 0.021	2.148GlnLys: 2.148 ± 0.022	3.541GlnLeu: 3.541 ± 0.033	0.832GlnMet: 0.832 ± 0.015	1.575GlnAsn: 1.575 ± 0.023	2.821GlnPro: 2.821 ± 0.041	3.092GlnGln: 3.092 ± 0.077	2.724GlnArg: 2.724 ± 0.03	3.258GlnSer: 3.258 ± 0.031	2.262GlnThr: 2.262 ± 0.028	2.103GlnVal: 2.103 ± 0.021	0.523GlnTrp: 0.523 ± 0.011	1.163GlnTyr: 1.163 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.539ArgAla: 4.539 ± 0.035	0.762ArgCys: 0.762 ± 0.014	3.4ArgAsp: 3.4 ± 0.034	4.004ArgGlu: 4.004 ± 0.041	2.091ArgPhe: 2.091 ± 0.022	3.746ArgGly: 3.746 ± 0.042	1.603ArgHis: 1.603 ± 0.024	2.973ArgIle: 2.973 ± 0.024	3.554ArgLys: 3.554 ± 0.034	5.529ArgLeu: 5.529 ± 0.045	1.318ArgMet: 1.318 ± 0.018	2.376ArgAsn: 2.376 ± 0.025	3.558ArgPro: 3.558 ± 0.036	2.682ArgGln: 2.682 ± 0.026	5.246ArgArg: 5.246 ± 0.057	5.002ArgSer: 5.002 ± 0.046	3.189ArgThr: 3.189 ± 0.028	3.306ArgVal: 3.306 ± 0.029	0.864ArgTrp: 0.864 ± 0.013	1.715ArgTyr: 1.715 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.547SerAla: 6.547 ± 0.042	0.964SerCys: 0.964 ± 0.016	4.181SerAsp: 4.181 ± 0.035	4.247SerGlu: 4.247 ± 0.041	3.092SerPhe: 3.092 ± 0.031	5.589SerGly: 5.589 ± 0.041	2.144SerHis: 2.144 ± 0.026	4.393SerIle: 4.393 ± 0.036	4.288SerLys: 4.288 ± 0.037	7.603SerLeu: 7.603 ± 0.048	1.859SerMet: 1.859 ± 0.022	3.37SerAsn: 3.37 ± 0.03	5.846SerPro: 5.846 ± 0.059	3.554SerGln: 3.554 ± 0.033	5.513SerArg: 5.513 ± 0.05	9.819SerSer: 9.819 ± 0.081	5.9SerThr: 5.9 ± 0.046	4.55SerVal: 4.55 ± 0.033	1.074SerTrp: 1.074 ± 0.017	2.161SerTyr: 2.161 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	5.147ThrAla: 5.147 ± 0.039	0.752ThrCys: 0.752 ± 0.015	2.803ThrAsp: 2.803 ± 0.025	3.209ThrGlu: 3.209 ± 0.039	2.118ThrPhe: 2.118 ± 0.022	4.049ThrGly: 4.049 ± 0.039	1.288ThrHis: 1.288 ± 0.019	3.138ThrIle: 3.138 ± 0.032	2.718ThrLys: 2.718 ± 0.027	5.149ThrLeu: 5.149 ± 0.037	1.184ThrMet: 1.184 ± 0.016	2.159ThrAsn: 2.159 ± 0.026	4.484ThrPro: 4.484 ± 0.047	2.082ThrGln: 2.082 ± 0.023	3.104ThrArg: 3.104 ± 0.027	5.591ThrSer: 5.591 ± 0.042	4.205ThrThr: 4.205 ± 0.043	3.56ThrVal: 3.56 ± 0.035	0.752ThrTrp: 0.752 ± 0.013	1.541ThrTyr: 1.541 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.761ValAla: 4.761 ± 0.038	0.814ValCys: 0.814 ± 0.014	3.569ValAsp: 3.569 ± 0.031	3.817ValGlu: 3.817 ± 0.033	2.32ValPhe: 2.32 ± 0.023	3.66ValGly: 3.66 ± 0.035	1.322ValHis: 1.322 ± 0.018	3.049ValIle: 3.049 ± 0.031	2.993ValLys: 2.993 ± 0.031	5.284ValLeu: 5.284 ± 0.041	1.251ValMet: 1.251 ± 0.017	2.192ValAsn: 2.192 ± 0.024	3.448ValPro: 3.448 ± 0.034	2.215ValGln: 2.215 ± 0.023	3.253ValArg: 3.253 ± 0.023	4.664ValSer: 4.664 ± 0.033	3.351ValThr: 3.351 ± 0.033	3.923ValVal: 3.923 ± 0.035	0.753ValTrp: 0.753 ± 0.015	1.676ValTyr: 1.676 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.004TrpAla: 1.004 ± 0.018	0.176TrpCys: 0.176 ± 0.007	0.828TrpAsp: 0.828 ± 0.016	0.806TrpGlu: 0.806 ± 0.015	0.473TrpPhe: 0.473 ± 0.011	0.804TrpGly: 0.804 ± 0.014	0.328TrpHis: 0.328 ± 0.01	0.728TrpIle: 0.728 ± 0.015	0.811TrpLys: 0.811 ± 0.014	1.226TrpLeu: 1.226 ± 0.022	0.345TrpMet: 0.345 ± 0.01	0.597TrpAsn: 0.597 ± 0.012	0.56TrpPro: 0.56 ± 0.012	0.495TrpGln: 0.495 ± 0.012	0.889TrpArg: 0.889 ± 0.014	0.982TrpSer: 0.982 ± 0.015	0.802TrpThr: 0.802 ± 0.013	0.787TrpVal: 0.787 ± 0.014	0.245TrpTrp: 0.245 ± 0.008	0.387TrpTyr: 0.387 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.958TyrAla: 1.958 ± 0.022	0.41TyrCys: 0.41 ± 0.01	1.604TyrAsp: 1.604 ± 0.02	1.509TyrGlu: 1.509 ± 0.017	1.183TyrPhe: 1.183 ± 0.02	1.97TyrGly: 1.97 ± 0.025	0.801TyrHis: 0.801 ± 0.014	1.555TyrIle: 1.555 ± 0.019	1.161TyrLys: 1.161 ± 0.016	2.692TyrLeu: 2.692 ± 0.025	0.602TyrMet: 0.602 ± 0.013	1.108TyrAsn: 1.108 ± 0.016	1.566TyrPro: 1.566 ± 0.021	1.156TyrGln: 1.156 ± 0.019	1.647TyrArg: 1.647 ± 0.022	2.161TyrSer: 2.161 ± 0.022	1.605TyrThr: 1.605 ± 0.017	1.495TyrVal: 1.495 ± 0.019	0.404TyrTrp: 0.404 ± 0.011	0.909TyrTyr: 0.909 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8921 proteins (4257366 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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