Amino acid dipepetide frequency for Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) (Brown rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.147AlaAla: 9.147 ± 0.062	1.164AlaCys: 1.164 ± 0.018	4.406AlaAsp: 4.406 ± 0.035	5.26AlaGlu: 5.26 ± 0.038	3.267AlaPhe: 3.267 ± 0.027	5.98AlaGly: 5.98 ± 0.035	2.113AlaHis: 2.113 ± 0.019	4.006AlaIle: 4.006 ± 0.03	3.999AlaLys: 3.999 ± 0.036	8.694AlaLeu: 8.694 ± 0.055	1.961AlaMet: 1.961 ± 0.022	2.649AlaAsn: 2.649 ± 0.022	5.553AlaPro: 5.553 ± 0.051	3.419AlaGln: 3.419 ± 0.028	5.716AlaArg: 5.716 ± 0.04	7.75AlaSer: 7.75 ± 0.046	5.028AlaThr: 5.028 ± 0.033	5.855AlaVal: 5.855 ± 0.041	1.253AlaTrp: 1.253 ± 0.018	2.377AlaTyr: 2.377 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	1.04CysAla: 1.04 ± 0.016	0.234CysCys: 0.234 ± 0.007	0.646CysAsp: 0.646 ± 0.013	0.606CysGlu: 0.606 ± 0.01	0.518CysPhe: 0.518 ± 0.012	0.928CysGly: 0.928 ± 0.014	0.335CysHis: 0.335 ± 0.008	0.667CysIle: 0.667 ± 0.013	0.505CysLys: 0.505 ± 0.01	1.286CysLeu: 1.286 ± 0.018	0.287CysMet: 0.287 ± 0.008	0.379CysAsn: 0.379 ± 0.01	0.773CysPro: 0.773 ± 0.015	0.439CysGln: 0.439 ± 0.01	0.793CysArg: 0.793 ± 0.014	0.926CysSer: 0.926 ± 0.015	0.712CysThr: 0.712 ± 0.013	0.817CysVal: 0.817 ± 0.015	0.213CysTrp: 0.213 ± 0.007	0.346CysTyr: 0.346 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.081AspAla: 5.081 ± 0.032	0.609AspCys: 0.609 ± 0.012	3.984AspAsp: 3.984 ± 0.037	4.525AspGlu: 4.525 ± 0.038	2.036AspPhe: 2.036 ± 0.024	4.016AspGly: 4.016 ± 0.028	1.187AspHis: 1.187 ± 0.018	2.983AspIle: 2.983 ± 0.032	2.235AspLys: 2.235 ± 0.024	4.98AspLeu: 4.98 ± 0.031	1.248AspMet: 1.248 ± 0.016	1.619AspAsn: 1.619 ± 0.021	3.607AspPro: 3.607 ± 0.026	1.629AspGln: 1.629 ± 0.021	3.066AspArg: 3.066 ± 0.029	3.884AspSer: 3.884 ± 0.03	2.837AspThr: 2.837 ± 0.027	4.145AspVal: 4.145 ± 0.03	0.929AspTrp: 0.929 ± 0.015	1.547AspTyr: 1.547 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.401GluAla: 5.401 ± 0.042	0.677GluCys: 0.677 ± 0.013	4.381GluAsp: 4.381 ± 0.039	5.903GluGlu: 5.903 ± 0.059	1.833GluPhe: 1.833 ± 0.022	4.234GluGly: 4.234 ± 0.035	1.478GluHis: 1.478 ± 0.018	2.68GluIle: 2.68 ± 0.024	3.372GluLys: 3.372 ± 0.036	5.319GluLeu: 5.319 ± 0.042	1.36GluMet: 1.36 ± 0.02	1.852GluAsn: 1.852 ± 0.023	2.864GluPro: 2.864 ± 0.032	2.366GluGln: 2.366 ± 0.022	4.375GluArg: 4.375 ± 0.037	4.066GluSer: 4.066 ± 0.03	3.047GluThr: 3.047 ± 0.026	3.943GluVal: 3.943 ± 0.03	1.012GluTrp: 1.012 ± 0.015	1.708GluTyr: 1.708 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.139PheAla: 3.139 ± 0.029	0.51PheCys: 0.51 ± 0.01	2.171PheAsp: 2.171 ± 0.021	1.959PheGlu: 1.959 ± 0.021	1.441PhePhe: 1.441 ± 0.021	2.669PheGly: 2.669 ± 0.032	0.891PheHis: 0.891 ± 0.016	1.703PheIle: 1.703 ± 0.018	1.428PheLys: 1.428 ± 0.017	3.439PheLeu: 3.439 ± 0.032	0.738PheMet: 0.738 ± 0.013	1.252PheAsn: 1.252 ± 0.016	2.027PhePro: 2.027 ± 0.024	1.206PheGln: 1.206 ± 0.015	1.966PheArg: 1.966 ± 0.017	2.829PheSer: 2.829 ± 0.027	2.085PheThr: 2.085 ± 0.02	2.467PheVal: 2.467 ± 0.024	0.583PheTrp: 0.583 ± 0.014	1.034PheTyr: 1.034 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.459GlyAla: 5.459 ± 0.043	0.879GlyCys: 0.879 ± 0.016	3.62GlyAsp: 3.62 ± 0.03	3.839GlyGlu: 3.839 ± 0.031	2.483GlyPhe: 2.483 ± 0.026	5.587GlyGly: 5.587 ± 0.061	1.696GlyHis: 1.696 ± 0.022	3.2GlyIle: 3.2 ± 0.031	3.501GlyLys: 3.501 ± 0.031	5.858GlyLeu: 5.858 ± 0.04	1.543GlyMet: 1.543 ± 0.022	2.209GlyAsn: 2.209 ± 0.027	3.547GlyPro: 3.547 ± 0.031	2.412GlyGln: 2.412 ± 0.026	4.486GlyArg: 4.486 ± 0.031	5.677GlySer: 5.677 ± 0.044	4.052GlyThr: 4.052 ± 0.033	4.557GlyVal: 4.557 ± 0.037	1.185GlyTrp: 1.185 ± 0.017	2.048GlyTyr: 2.048 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.137HisAla: 2.137 ± 0.021	0.354HisCys: 0.354 ± 0.01	1.285HisAsp: 1.285 ± 0.017	1.297HisGlu: 1.297 ± 0.015	0.932HisPhe: 0.932 ± 0.015	1.621HisGly: 1.621 ± 0.02	0.81HisHis: 0.81 ± 0.015	1.239HisIle: 1.239 ± 0.015	0.911HisLys: 0.911 ± 0.011	2.45HisLeu: 2.45 ± 0.025	0.489HisMet: 0.489 ± 0.009	0.744HisAsn: 0.744 ± 0.011	1.924HisPro: 1.924 ± 0.024	0.842HisGln: 0.842 ± 0.014	1.632HisArg: 1.632 ± 0.021	1.92HisSer: 1.92 ± 0.025	1.362HisThr: 1.362 ± 0.017	1.636HisVal: 1.636 ± 0.018	0.366HisTrp: 0.366 ± 0.009	0.733HisTyr: 0.733 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.979IleAla: 3.979 ± 0.034	0.692IleCys: 0.692 ± 0.013	2.609IleAsp: 2.609 ± 0.023	2.542IleGlu: 2.542 ± 0.021	1.765IlePhe: 1.765 ± 0.024	2.878IleGly: 2.878 ± 0.031	1.173IleHis: 1.173 ± 0.017	2.243IleIle: 2.243 ± 0.025	1.922IleLys: 1.922 ± 0.022	4.408IleLeu: 4.408 ± 0.036	0.926IleMet: 0.926 ± 0.014	1.458IleAsn: 1.458 ± 0.02	3.092IlePro: 3.092 ± 0.024	1.701IleGln: 1.701 ± 0.02	2.83IleArg: 2.83 ± 0.025	3.514IleSer: 3.514 ± 0.029	2.6IleThr: 2.6 ± 0.028	3.176IleVal: 3.176 ± 0.029	0.715IleTrp: 0.715 ± 0.012	1.304IleTyr: 1.304 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.27LysAla: 4.27 ± 0.035	0.484LysCys: 0.484 ± 0.011	2.557LysAsp: 2.557 ± 0.027	3.373LysGlu: 3.373 ± 0.029	1.281LysPhe: 1.281 ± 0.017	3.015LysGly: 3.015 ± 0.029	1.078LysHis: 1.078 ± 0.016	1.962LysIle: 1.962 ± 0.019	2.972LysLys: 2.972 ± 0.037	3.814LysLeu: 3.814 ± 0.031	0.923LysMet: 0.923 ± 0.016	1.373LysAsn: 1.373 ± 0.018	2.574LysPro: 2.574 ± 0.026	1.623LysGln: 1.623 ± 0.021	3.431LysArg: 3.431 ± 0.032	3.087LysSer: 3.087 ± 0.032	2.526LysThr: 2.526 ± 0.026	2.824LysVal: 2.824 ± 0.026	0.668LysTrp: 0.668 ± 0.011	1.298LysTyr: 1.298 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.423LeuAla: 8.423 ± 0.053	1.273LeuCys: 1.273 ± 0.021	5.19LeuAsp: 5.19 ± 0.037	5.564LeuGlu: 5.564 ± 0.042	3.297LeuPhe: 3.297 ± 0.031	5.829LeuGly: 5.829 ± 0.042	2.41LeuHis: 2.41 ± 0.022	3.689LeuIle: 3.689 ± 0.034	3.999LeuLys: 3.999 ± 0.028	8.624LeuLeu: 8.624 ± 0.062	1.727LeuMet: 1.727 ± 0.023	2.902LeuAsn: 2.902 ± 0.025	6.216LeuPro: 6.216 ± 0.044	3.716LeuGln: 3.716 ± 0.035	6.311LeuArg: 6.311 ± 0.041	7.823LeuSer: 7.823 ± 0.059	5.145LeuThr: 5.145 ± 0.038	5.859LeuVal: 5.859 ± 0.046	1.271LeuTrp: 1.271 ± 0.019	2.442LeuTyr: 2.442 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	1.947MetAla: 1.947 ± 0.019	0.242MetCys: 0.242 ± 0.007	1.236MetAsp: 1.236 ± 0.016	1.249MetGlu: 1.249 ± 0.017	0.719MetPhe: 0.719 ± 0.014	1.351MetGly: 1.351 ± 0.019	0.52MetHis: 0.52 ± 0.011	0.88MetIle: 0.88 ± 0.015	0.954MetLys: 0.954 ± 0.016	1.839MetLeu: 1.839 ± 0.02	0.496MetMet: 0.496 ± 0.011	0.714MetAsn: 0.714 ± 0.013	1.325MetPro: 1.325 ± 0.017	0.849MetGln: 0.849 ± 0.014	1.285MetArg: 1.285 ± 0.016	1.973MetSer: 1.973 ± 0.021	1.236MetThr: 1.236 ± 0.015	1.236MetVal: 1.236 ± 0.016	0.273MetTrp: 0.273 ± 0.007	0.558MetTyr: 0.558 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.996AsnAla: 2.996 ± 0.024	0.375AsnCys: 0.375 ± 0.009	1.635AsnAsp: 1.635 ± 0.017	1.705AsnGlu: 1.705 ± 0.021	1.148AsnPhe: 1.148 ± 0.018	2.548AsnGly: 2.548 ± 0.028	0.72AsnHis: 0.72 ± 0.013	1.722AsnIle: 1.722 ± 0.018	1.26AsnLys: 1.26 ± 0.018	2.901AsnLeu: 2.901 ± 0.026	0.717AsnMet: 0.717 ± 0.012	1.126AsnAsn: 1.126 ± 0.017	2.282AsnPro: 2.282 ± 0.022	1.042AsnGln: 1.042 ± 0.016	1.705AsnArg: 1.705 ± 0.02	2.221AsnSer: 2.221 ± 0.021	1.87AsnThr: 1.87 ± 0.022	2.285AsnVal: 2.285 ± 0.021	0.488AsnTrp: 0.488 ± 0.01	0.89AsnTyr: 0.89 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	6.083ProAla: 6.083 ± 0.054	0.554ProCys: 0.554 ± 0.013	3.442ProAsp: 3.442 ± 0.029	4.0ProGlu: 4.0 ± 0.035	2.147ProPhe: 2.147 ± 0.021	4.183ProGly: 4.183 ± 0.037	1.572ProHis: 1.572 ± 0.017	2.508ProIle: 2.508 ± 0.024	2.501ProLys: 2.501 ± 0.025	5.376ProLeu: 5.376 ± 0.036	1.112ProMet: 1.112 ± 0.014	2.053ProAsn: 2.053 ± 0.019	6.505ProPro: 6.505 ± 0.086	2.342ProGln: 2.342 ± 0.029	3.907ProArg: 3.907 ± 0.038	7.158ProSer: 7.158 ± 0.063	4.11ProThr: 4.11 ± 0.032	4.044ProVal: 4.044 ± 0.032	0.762ProTrp: 0.762 ± 0.013	1.66ProTyr: 1.66 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.495GlnAla: 3.495 ± 0.03	0.455GlnCys: 0.455 ± 0.012	1.942GlnAsp: 1.942 ± 0.021	2.311GlnGlu: 2.311 ± 0.022	1.182GlnPhe: 1.182 ± 0.016	2.356GlnGly: 2.356 ± 0.025	0.961GlnHis: 0.961 ± 0.014	1.621GlnIle: 1.621 ± 0.02	1.574GlnLys: 1.574 ± 0.018	3.288GlnLeu: 3.288 ± 0.026	0.816GlnMet: 0.816 ± 0.014	1.204GlnAsn: 1.204 ± 0.018	2.336GlnPro: 2.336 ± 0.028	1.84GlnGln: 1.84 ± 0.037	2.488GlnArg: 2.488 ± 0.023	2.83GlnSer: 2.83 ± 0.028	2.097GlnThr: 2.097 ± 0.022	2.25GlnVal: 2.25 ± 0.022	0.553GlnTrp: 0.553 ± 0.01	1.128GlnTyr: 1.128 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.58ArgAla: 5.58 ± 0.035	0.818ArgCys: 0.818 ± 0.011	3.483ArgAsp: 3.483 ± 0.028	4.25ArgGlu: 4.25 ± 0.034	2.195ArgPhe: 2.195 ± 0.025	3.934ArgGly: 3.934 ± 0.034	1.603ArgHis: 1.603 ± 0.019	2.914ArgIle: 2.914 ± 0.027	3.442ArgLys: 3.442 ± 0.032	5.959ArgLeu: 5.959 ± 0.041	1.417ArgMet: 1.417 ± 0.017	2.021ArgAsn: 2.021 ± 0.021	3.95ArgPro: 3.95 ± 0.035	2.409ArgGln: 2.409 ± 0.024	5.67ArgArg: 5.67 ± 0.046	5.152ArgSer: 5.152 ± 0.04	3.566ArgThr: 3.566 ± 0.029	3.907ArgVal: 3.907 ± 0.025	1.059ArgTrp: 1.059 ± 0.016	1.73ArgTyr: 1.73 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.216SerAla: 7.216 ± 0.048	0.88SerCys: 0.88 ± 0.014	4.282SerAsp: 4.282 ± 0.036	4.136SerGlu: 4.136 ± 0.033	2.87SerPhe: 2.87 ± 0.025	5.726SerGly: 5.726 ± 0.041	1.955SerHis: 1.955 ± 0.021	3.593SerIle: 3.593 ± 0.029	3.332SerLys: 3.332 ± 0.029	7.589SerLeu: 7.589 ± 0.055	1.676SerMet: 1.676 ± 0.02	2.546SerAsn: 2.546 ± 0.028	6.257SerPro: 6.257 ± 0.054	3.023SerGln: 3.023 ± 0.028	5.249SerArg: 5.249 ± 0.044	9.363SerSer: 9.363 ± 0.095	5.507SerThr: 5.507 ± 0.049	5.086SerVal: 5.086 ± 0.038	1.104SerTrp: 1.104 ± 0.016	2.044SerTyr: 2.044 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.058ThrAla: 5.058 ± 0.035	0.743ThrCys: 0.743 ± 0.014	2.727ThrAsp: 2.727 ± 0.023	2.85ThrGlu: 2.85 ± 0.025	2.25ThrPhe: 2.25 ± 0.021	3.923ThrGly: 3.923 ± 0.033	1.39ThrHis: 1.39 ± 0.016	2.806ThrIle: 2.806 ± 0.026	2.31ThrLys: 2.31 ± 0.024	5.617ThrLeu: 5.617 ± 0.04	1.125ThrMet: 1.125 ± 0.013	1.784ThrAsn: 1.784 ± 0.021	4.504ThrPro: 4.504 ± 0.039	1.874ThrGln: 1.874 ± 0.02	3.355ThrArg: 3.355 ± 0.029	5.32ThrSer: 5.32 ± 0.045	3.75ThrThr: 3.75 ± 0.036	3.823ThrVal: 3.823 ± 0.031	0.835ThrTrp: 0.835 ± 0.015	1.616ThrTyr: 1.616 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.562ValAla: 5.562 ± 0.034	0.88ValCys: 0.88 ± 0.013	3.871ValAsp: 3.871 ± 0.03	4.006ValGlu: 4.006 ± 0.034	2.481ValPhe: 2.481 ± 0.024	4.142ValGly: 4.142 ± 0.032	1.675ValHis: 1.675 ± 0.018	3.021ValIle: 3.021 ± 0.03	3.029ValLys: 3.029 ± 0.028	6.33ValLeu: 6.33 ± 0.048	1.349ValMet: 1.349 ± 0.019	2.138ValAsn: 2.138 ± 0.022	4.36ValPro: 4.36 ± 0.032	2.472ValGln: 2.472 ± 0.022	3.989ValArg: 3.989 ± 0.029	4.916ValSer: 4.916 ± 0.029	3.587ValThr: 3.587 ± 0.029	4.736ValVal: 4.736 ± 0.039	0.998ValTrp: 0.998 ± 0.014	1.863ValTyr: 1.863 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	1.181TrpAla: 1.181 ± 0.016	0.22TrpCys: 0.22 ± 0.007	0.964TrpAsp: 0.964 ± 0.015	0.911TrpGlu: 0.911 ± 0.015	0.565TrpPhe: 0.565 ± 0.012	0.918TrpGly: 0.918 ± 0.014	0.371TrpHis: 0.371 ± 0.009	0.735TrpIle: 0.735 ± 0.013	0.791TrpLys: 0.791 ± 0.013	1.356TrpLeu: 1.356 ± 0.02	0.376TrpMet: 0.376 ± 0.009	0.589TrpAsn: 0.589 ± 0.012	0.674TrpPro: 0.674 ± 0.013	0.542TrpGln: 0.542 ± 0.011	1.096TrpArg: 1.096 ± 0.016	1.068TrpSer: 1.068 ± 0.016	0.924TrpThr: 0.924 ± 0.014	0.95TrpVal: 0.95 ± 0.015	0.302TrpTrp: 0.302 ± 0.008	0.459TrpTyr: 0.459 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.401TyrAla: 2.401 ± 0.026	0.404TyrCys: 0.404 ± 0.009	1.714TyrAsp: 1.714 ± 0.02	1.586TyrGlu: 1.586 ± 0.02	1.123TyrPhe: 1.123 ± 0.016	2.002TyrGly: 2.002 ± 0.023	0.745TyrHis: 0.745 ± 0.013	1.358TyrIle: 1.358 ± 0.018	1.097TyrLys: 1.097 ± 0.015	2.585TyrLeu: 2.585 ± 0.028	0.596TyrMet: 0.596 ± 0.011	1.022TyrAsn: 1.022 ± 0.016	1.65TyrPro: 1.65 ± 0.022	0.983TyrGln: 0.983 ± 0.014	1.71TyrArg: 1.71 ± 0.02	1.958TyrSer: 1.958 ± 0.023	1.62TyrThr: 1.62 ± 0.02	1.806TyrVal: 1.806 ± 0.024	0.422TyrTrp: 0.422 ± 0.009	0.904TyrTyr: 0.904 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11735 proteins (4956750 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---