Amino acid dipepetide frequency for Poinsettia latent virus (isolate Euphorbia pulcherrima/Germany/Siepen/2005) (PnLV) (Poinsettia cryptic virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.863AlaAla: 3.863 ± 1.111
0.429AlaCys: 0.429 ± 0.523
3.433AlaAsp: 3.433 ± 1.307
4.292AlaGlu: 4.292 ± 1.454
2.575AlaPhe: 2.575 ± 0.455
3.863AlaGly: 3.863 ± 0.884
0.858AlaHis: 0.858 ± 1.354
2.575AlaIle: 2.575 ± 0.81
3.863AlaLys: 3.863 ± 1.279
6.009AlaLeu: 6.009 ± 0.459
1.717AlaMet: 1.717 ± 1.471
1.288AlaAsn: 1.288 ± 0.452
2.575AlaPro: 2.575 ± 0.77
2.146AlaGln: 2.146 ± 0.475
3.004AlaArg: 3.004 ± 0.904
3.433AlaSer: 3.433 ± 0.762
3.004AlaThr: 3.004 ± 1.057
7.296AlaVal: 7.296 ± 1.687
1.717AlaTrp: 1.717 ± 0.559
2.575AlaTyr: 2.575 ± 0.467
0.0AlaXaa: 0.0 ± 0.0
Cys
1.717CysAla: 1.717 ± 0.381
0.858CysCys: 0.858 ± 0.308
1.288CysAsp: 1.288 ± 0.606
0.0CysGlu: 0.0 ± 0.0
0.429CysPhe: 0.429 ± 0.677
1.717CysGly: 1.717 ± 0.672
0.858CysHis: 0.858 ± 0.308
0.858CysIle: 0.858 ± 0.915
0.429CysLys: 0.429 ± 0.263
3.863CysLeu: 3.863 ± 1.321
0.0CysMet: 0.0 ± 0.0
0.858CysAsn: 0.858 ± 0.572
3.433CysPro: 3.433 ± 1.23
0.0CysGln: 0.0 ± 0.0
0.858CysArg: 0.858 ± 0.48
4.292CysSer: 4.292 ± 1.055
0.858CysThr: 0.858 ± 0.308
3.004CysVal: 3.004 ± 0.676
0.858CysTrp: 0.858 ± 0.308
0.429CysTyr: 0.429 ± 0.523
0.0CysXaa: 0.0 ± 0.0
Asp
1.288AspAla: 1.288 ± 0.57
1.288AspCys: 1.288 ± 0.77
3.433AspAsp: 3.433 ± 0.844
4.721AspGlu: 4.721 ± 1.132
2.575AspPhe: 2.575 ± 0.499
3.433AspGly: 3.433 ± 1.345
0.429AspHis: 0.429 ± 0.263
3.004AspIle: 3.004 ± 1.91
2.575AspLys: 2.575 ± 0.923
8.155AspLeu: 8.155 ± 1.525
0.0AspMet: 0.0 ± 0.0
0.429AspAsn: 0.429 ± 0.677
1.288AspPro: 1.288 ± 0.578
1.717AspGln: 1.717 ± 0.96
1.288AspArg: 1.288 ± 0.518
2.575AspSer: 2.575 ± 0.725
1.288AspThr: 1.288 ± 0.518
2.146AspVal: 2.146 ± 0.475
1.717AspTrp: 1.717 ± 0.672
1.288AspTyr: 1.288 ± 1.522
0.0AspXaa: 0.0 ± 0.0
Glu
5.579GluAla: 5.579 ± 0.973
0.429GluCys: 0.429 ± 0.263
2.146GluAsp: 2.146 ± 0.727
4.292GluGlu: 4.292 ± 1.454
1.288GluPhe: 1.288 ± 0.789
3.433GluGly: 3.433 ± 0.736
1.717GluHis: 1.717 ± 0.615
3.433GluIle: 3.433 ± 0.736
5.15GluLys: 5.15 ± 1.865
5.579GluLeu: 5.579 ± 1.056
1.717GluMet: 1.717 ± 0.381
2.575GluAsn: 2.575 ± 0.399
1.717GluPro: 1.717 ± 0.381
1.288GluGln: 1.288 ± 0.452
3.004GluArg: 3.004 ± 0.482
5.579GluSer: 5.579 ± 1.337
1.288GluThr: 1.288 ± 0.385
3.433GluVal: 3.433 ± 0.73
1.717GluTrp: 1.717 ± 0.422
0.429GluTyr: 0.429 ± 0.523
0.0GluXaa: 0.0 ± 0.0
Phe
2.146PheAla: 2.146 ± 1.033
1.288PheCys: 1.288 ± 0.452
1.288PheAsp: 1.288 ± 0.452
1.717PheGlu: 1.717 ± 0.381
0.0PhePhe: 0.0 ± 0.0
1.288PheGly: 1.288 ± 0.789
0.0PheHis: 0.0 ± 0.0
2.146PheIle: 2.146 ± 0.473
3.004PheLys: 3.004 ± 0.553
4.721PheLeu: 4.721 ± 2.04
0.429PheMet: 0.429 ± 0.747
0.858PheAsn: 0.858 ± 0.308
0.429PhePro: 0.429 ± 0.677
0.429PheGln: 0.429 ± 0.263
3.863PheArg: 3.863 ± 0.859
3.433PheSer: 3.433 ± 0.669
1.288PheThr: 1.288 ± 1.522
0.858PheVal: 0.858 ± 0.572
0.429PheTrp: 0.429 ± 0.677
1.717PheTyr: 1.717 ± 0.672
0.0PheXaa: 0.0 ± 0.0
Gly
4.721GlyAla: 4.721 ± 0.953
1.717GlyCys: 1.717 ± 0.615
3.004GlyAsp: 3.004 ± 1.021
4.721GlyGlu: 4.721 ± 1.267
5.15GlyPhe: 5.15 ± 1.679
1.717GlyGly: 1.717 ± 0.96
1.288GlyHis: 1.288 ± 0.452
4.721GlyIle: 4.721 ± 0.859
5.15GlyLys: 5.15 ± 1.159
5.579GlyLeu: 5.579 ± 0.358
1.288GlyMet: 1.288 ± 0.385
2.575GlyAsn: 2.575 ± 0.725
3.863GlyPro: 3.863 ± 1.175
0.858GlyGln: 0.858 ± 0.526
6.009GlyArg: 6.009 ± 0.705
6.009GlySer: 6.009 ± 0.459
3.433GlyThr: 3.433 ± 0.736
5.15GlyVal: 5.15 ± 0.836
1.288GlyTrp: 1.288 ± 0.578
4.721GlyTyr: 4.721 ± 0.649
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.858HisCys: 0.858 ± 0.308
0.858HisAsp: 0.858 ± 0.572
0.429HisGlu: 0.429 ± 0.263
0.429HisPhe: 0.429 ± 0.677
1.288HisGly: 1.288 ± 0.452
0.0HisHis: 0.0 ± 0.0
0.858HisIle: 0.858 ± 0.572
2.146HisLys: 2.146 ± 0.727
2.146HisLeu: 2.146 ± 0.727
0.429HisMet: 0.429 ± 0.677
1.288HisAsn: 1.288 ± 0.452
0.429HisPro: 0.429 ± 0.263
0.858HisGln: 0.858 ± 0.308
0.858HisArg: 0.858 ± 0.526
3.863HisSer: 3.863 ± 1.321
0.429HisThr: 0.429 ± 0.523
1.288HisVal: 1.288 ± 0.518
0.858HisTrp: 0.858 ± 0.308
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.858IleAla: 0.858 ± 0.308
3.433IleCys: 3.433 ± 0.669
4.292IleAsp: 4.292 ± 0.666
4.292IleGlu: 4.292 ± 2.129
2.146IlePhe: 2.146 ± 0.727
3.433IleGly: 3.433 ± 0.859
0.858IleHis: 0.858 ± 0.308
3.433IleIle: 3.433 ± 1.496
1.288IleLys: 1.288 ± 0.385
2.575IleLeu: 2.575 ± 0.778
2.146IleMet: 2.146 ± 0.727
0.429IleAsn: 0.429 ± 0.263
7.725IlePro: 7.725 ± 0.946
1.717IleGln: 1.717 ± 1.83
0.858IleArg: 0.858 ± 0.48
7.296IleSer: 7.296 ± 3.47
3.004IleThr: 3.004 ± 1.021
1.717IleVal: 1.717 ± 0.654
2.575IleTrp: 2.575 ± 0.923
0.429IleTyr: 0.429 ± 0.263
0.0IleXaa: 0.0 ± 0.0
Lys
5.15LysAla: 5.15 ± 1.557
0.858LysCys: 0.858 ± 0.308
1.717LysAsp: 1.717 ± 0.615
3.433LysGlu: 3.433 ± 1.496
1.717LysPhe: 1.717 ± 0.422
6.009LysGly: 6.009 ± 1.304
1.288LysHis: 1.288 ± 0.452
1.717LysIle: 1.717 ± 0.747
1.717LysLys: 1.717 ± 0.381
4.721LysLeu: 4.721 ± 0.472
1.288LysMet: 1.288 ± 0.385
4.292LysAsn: 4.292 ± 1.538
3.433LysPro: 3.433 ± 0.736
3.433LysGln: 3.433 ± 0.762
3.863LysArg: 3.863 ± 1.494
7.296LysSer: 7.296 ± 0.703
3.863LysThr: 3.863 ± 0.231
3.004LysVal: 3.004 ± 0.72
0.858LysTrp: 0.858 ± 0.572
0.429LysTyr: 0.429 ± 0.523
0.0LysXaa: 0.0 ± 0.0
Leu
7.725LeuAla: 7.725 ± 1.267
3.863LeuCys: 3.863 ± 0.759
3.433LeuAsp: 3.433 ± 1.998
5.15LeuGlu: 5.15 ± 1.305
2.146LeuPhe: 2.146 ± 1.033
5.15LeuGly: 5.15 ± 1.199
2.575LeuHis: 2.575 ± 0.904
6.009LeuIle: 6.009 ± 1.304
3.863LeuLys: 3.863 ± 0.896
10.3LeuLeu: 10.3 ± 1.319
5.579LeuMet: 5.579 ± 1.928
3.004LeuAsn: 3.004 ± 0.894
3.433LeuPro: 3.433 ± 0.99
2.146LeuGln: 2.146 ± 0.475
5.15LeuArg: 5.15 ± 1.338
13.734LeuSer: 13.734 ± 1.249
6.438LeuThr: 6.438 ± 0.806
7.296LeuVal: 7.296 ± 1.389
1.717LeuTrp: 1.717 ± 0.422
3.004LeuTyr: 3.004 ± 1.588
0.0LeuXaa: 0.0 ± 0.0
Met
1.717MetAla: 1.717 ± 0.381
0.0MetCys: 0.0 ± 0.0
0.858MetAsp: 0.858 ± 0.915
0.429MetGlu: 0.429 ± 0.263
0.0MetPhe: 0.0 ± 0.0
3.004MetGly: 3.004 ± 0.682
0.0MetHis: 0.0 ± 0.0
1.717MetIle: 1.717 ± 0.615
0.858MetLys: 0.858 ± 0.308
3.004MetLeu: 3.004 ± 0.977
0.858MetMet: 0.858 ± 0.308
0.429MetAsn: 0.429 ± 0.351
0.0MetPro: 0.0 ± 0.0
1.717MetGln: 1.717 ± 1.799
0.858MetArg: 0.858 ± 0.572
2.146MetSer: 2.146 ± 0.796
3.004MetThr: 3.004 ± 1.192
0.858MetVal: 0.858 ± 0.48
0.0MetTrp: 0.0 ± 0.0
0.858MetTyr: 0.858 ± 0.308
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
1.717AsnCys: 1.717 ± 0.672
1.717AsnAsp: 1.717 ± 0.672
3.004AsnGlu: 3.004 ± 1.192
2.146AsnPhe: 2.146 ± 0.727
2.575AsnGly: 2.575 ± 0.77
1.288AsnHis: 1.288 ± 0.452
2.146AsnIle: 2.146 ± 1.21
0.858AsnLys: 0.858 ± 0.48
6.009AsnLeu: 6.009 ± 0.42
0.0AsnMet: 0.0 ± 0.0
0.858AsnAsn: 0.858 ± 1.354
0.429AsnPro: 0.429 ± 0.263
1.717AsnGln: 1.717 ± 0.654
2.575AsnArg: 2.575 ± 0.399
6.438AsnSer: 6.438 ± 1.346
1.717AsnThr: 1.717 ± 0.672
3.433AsnVal: 3.433 ± 0.99
0.429AsnTrp: 0.429 ± 0.263
2.575AsnTyr: 2.575 ± 0.467
0.0AsnXaa: 0.0 ± 0.0
Pro
5.15ProAla: 5.15 ± 1.339
2.575ProCys: 2.575 ± 0.499
2.146ProAsp: 2.146 ± 0.518
3.433ProGlu: 3.433 ± 0.859
1.288ProPhe: 1.288 ± 0.518
4.292ProGly: 4.292 ± 0.931
1.288ProHis: 1.288 ± 0.452
2.146ProIle: 2.146 ± 0.518
3.433ProLys: 3.433 ± 0.736
2.575ProLeu: 2.575 ± 0.904
1.288ProMet: 1.288 ± 0.452
1.288ProAsn: 1.288 ± 0.518
3.433ProPro: 3.433 ± 1.23
1.288ProGln: 1.288 ± 0.452
1.288ProArg: 1.288 ± 0.452
6.009ProSer: 6.009 ± 1.731
2.146ProThr: 2.146 ± 0.473
5.15ProVal: 5.15 ± 0.665
0.429ProTrp: 0.429 ± 0.523
2.575ProTyr: 2.575 ± 0.904
0.0ProXaa: 0.0 ± 0.0
Gln
2.146GlnAla: 2.146 ± 0.473
0.858GlnCys: 0.858 ± 0.705
1.717GlnAsp: 1.717 ± 0.672
0.858GlnGlu: 0.858 ± 0.48
0.0GlnPhe: 0.0 ± 0.0
1.288GlnGly: 1.288 ± 0.57
0.429GlnHis: 0.429 ± 0.523
1.288GlnIle: 1.288 ± 0.385
2.146GlnLys: 2.146 ± 0.915
1.288GlnLeu: 1.288 ± 0.77
0.429GlnMet: 0.429 ± 0.472
2.575GlnAsn: 2.575 ± 0.642
0.429GlnPro: 0.429 ± 0.523
0.429GlnGln: 0.429 ± 0.677
2.575GlnArg: 2.575 ± 1.541
2.575GlnSer: 2.575 ± 1.104
0.858GlnThr: 0.858 ± 0.308
0.858GlnVal: 0.858 ± 0.48
1.717GlnTrp: 1.717 ± 0.615
1.288GlnTyr: 1.288 ± 0.385
0.0GlnXaa: 0.0 ± 0.0
Arg
1.288ArgAla: 1.288 ± 0.877
0.0ArgCys: 0.0 ± 0.0
0.858ArgAsp: 0.858 ± 0.526
2.146ArgGlu: 2.146 ± 1.315
0.858ArgPhe: 0.858 ± 1.354
4.292ArgGly: 4.292 ± 0.931
1.288ArgHis: 1.288 ± 0.452
3.433ArgIle: 3.433 ± 1.532
3.004ArgLys: 3.004 ± 1.257
9.442ArgLeu: 9.442 ± 2.031
0.429ArgMet: 0.429 ± 0.319
3.004ArgAsn: 3.004 ± 0.858
2.575ArgPro: 2.575 ± 1.104
0.858ArgGln: 0.858 ± 0.915
3.004ArgArg: 3.004 ± 0.949
6.438ArgSer: 6.438 ± 1.289
1.288ArgThr: 1.288 ± 0.743
4.721ArgVal: 4.721 ± 0.649
1.717ArgTrp: 1.717 ± 0.381
2.575ArgTyr: 2.575 ± 0.399
0.0ArgXaa: 0.0 ± 0.0
Ser
6.438SerAla: 6.438 ± 1.925
3.004SerCys: 3.004 ± 0.682
4.721SerAsp: 4.721 ± 0.881
6.438SerGlu: 6.438 ± 0.985
3.004SerPhe: 3.004 ± 1.769
10.3SerGly: 10.3 ± 0.643
1.717SerHis: 1.717 ± 0.672
4.721SerIle: 4.721 ± 1.132
7.725SerLys: 7.725 ± 1.582
11.159SerLeu: 11.159 ± 1.064
2.575SerMet: 2.575 ± 2.199
6.438SerAsn: 6.438 ± 1.701
7.296SerPro: 7.296 ± 1.152
1.717SerGln: 1.717 ± 0.381
3.863SerArg: 3.863 ± 2.3
11.159SerSer: 11.159 ± 0.708
3.433SerThr: 3.433 ± 0.419
7.296SerVal: 7.296 ± 0.801
2.575SerTrp: 2.575 ± 1.167
3.004SerTyr: 3.004 ± 0.72
0.0SerXaa: 0.0 ± 0.0
Thr
1.717ThrAla: 1.717 ± 0.866
1.717ThrCys: 1.717 ± 0.615
1.288ThrAsp: 1.288 ± 0.452
0.858ThrGlu: 0.858 ± 0.915
2.575ThrPhe: 2.575 ± 1.037
3.863ThrGly: 3.863 ± 2.488
0.429ThrHis: 0.429 ± 0.263
3.433ThrIle: 3.433 ± 0.669
2.575ThrLys: 2.575 ± 0.778
2.146ThrLeu: 2.146 ± 0.727
0.0ThrMet: 0.0 ± 0.0
2.575ThrAsn: 2.575 ± 0.81
3.433ThrPro: 3.433 ± 0.963
0.858ThrGln: 0.858 ± 0.308
2.146ThrArg: 2.146 ± 0.475
6.438ThrSer: 6.438 ± 0.783
3.433ThrThr: 3.433 ± 0.791
3.004ThrVal: 3.004 ± 0.66
0.858ThrTrp: 0.858 ± 0.915
0.858ThrTyr: 0.858 ± 0.308
0.0ThrXaa: 0.0 ± 0.0
Val
3.863ValAla: 3.863 ± 0.53
0.858ValCys: 0.858 ± 0.308
3.433ValAsp: 3.433 ± 1.171
4.292ValGlu: 4.292 ± 0.918
2.575ValPhe: 2.575 ± 1.104
7.296ValGly: 7.296 ± 1.224
0.429ValHis: 0.429 ± 0.677
3.004ValIle: 3.004 ± 0.652
5.579ValLys: 5.579 ± 1.165
6.438ValLeu: 6.438 ± 1.656
0.429ValMet: 0.429 ± 0.263
3.004ValAsn: 3.004 ± 1.385
4.721ValPro: 4.721 ± 2.011
2.146ValGln: 2.146 ± 0.475
4.721ValArg: 4.721 ± 0.331
5.579ValSer: 5.579 ± 2.05
1.717ValThr: 1.717 ± 0.866
5.579ValVal: 5.579 ± 1.54
0.0ValTrp: 0.0 ± 0.0
2.575ValTyr: 2.575 ± 0.81
0.0ValXaa: 0.0 ± 0.0
Trp
3.004TrpAla: 3.004 ± 0.21
0.0TrpCys: 0.0 ± 0.0
0.858TrpAsp: 0.858 ± 0.308
0.858TrpGlu: 0.858 ± 0.308
0.0TrpPhe: 0.0 ± 0.0
1.288TrpGly: 1.288 ± 0.452
0.429TrpHis: 0.429 ± 0.677
2.146TrpIle: 2.146 ± 0.518
1.717TrpLys: 1.717 ± 0.672
3.433TrpLeu: 3.433 ± 0.859
0.429TrpMet: 0.429 ± 0.263
0.429TrpAsn: 0.429 ± 0.677
0.429TrpPro: 0.429 ± 0.263
0.0TrpGln: 0.0 ± 0.0
1.717TrpArg: 1.717 ± 0.699
2.146TrpSer: 2.146 ± 0.473
0.858TrpThr: 0.858 ± 0.308
1.717TrpVal: 1.717 ± 0.615
0.0TrpTrp: 0.0 ± 0.0
0.429TrpTyr: 0.429 ± 0.523
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.146TyrAla: 2.146 ± 0.473
0.858TyrCys: 0.858 ± 0.48
2.146TyrAsp: 2.146 ± 2.418
0.429TyrGlu: 0.429 ± 0.263
0.858TyrPhe: 0.858 ± 0.526
3.433TyrGly: 3.433 ± 0.844
2.146TyrHis: 2.146 ± 0.518
1.717TyrIle: 1.717 ± 0.866
3.004TyrLys: 3.004 ± 0.652
2.575TyrLeu: 2.575 ± 0.467
0.858TyrMet: 0.858 ± 0.308
3.433TyrAsn: 3.433 ± 1.171
2.146TyrPro: 2.146 ± 1.671
0.429TyrGln: 0.429 ± 0.523
1.717TyrArg: 1.717 ± 0.747
2.146TyrSer: 2.146 ± 0.727
0.858TyrThr: 0.858 ± 1.047
0.429TyrVal: 0.429 ± 0.523
0.429TyrTrp: 0.429 ± 0.523
1.717TyrTyr: 1.717 ± 1.166
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2331 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski