Human papillomavirus type 61

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 3

Average proteome isoelectric point is 6.48

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q80950|VE1_HPV61 Replication protein E1 OS=Human papillomavirus type 61 OX=37116 GN=E1 PE=3 SV=1
MM1 pKa = 7.47HH2 pKa = 6.85GQVATIKK9 pKa = 10.73DD10 pKa = 3.37IVLEE14 pKa = 4.0EE15 pKa = 4.11RR16 pKa = 11.84PEE18 pKa = 4.21VVDD21 pKa = 3.87LHH23 pKa = 7.83CNEE26 pKa = 4.22QLLDD30 pKa = 3.69SSEE33 pKa = 4.43SEE35 pKa = 4.26EE36 pKa = 3.96EE37 pKa = 4.07DD38 pKa = 3.48SVRR41 pKa = 11.84EE42 pKa = 3.89QLVEE46 pKa = 3.95QAQQAYY52 pKa = 9.36RR53 pKa = 11.84VVTTCGICKK62 pKa = 10.07CPVRR66 pKa = 11.84LVVQCGDD73 pKa = 3.39ADD75 pKa = 4.05LKK77 pKa = 11.16VLHH80 pKa = 6.63EE81 pKa = 4.85LLLGDD86 pKa = 4.99LSIVCPGCAA95 pKa = 3.65

Molecular weight: 10.46 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q80948|VE6_HPV61 Protein E6 OS=Human papillomavirus type 61 OX=37116 GN=E6 PE=3 SV=1
FF1 pKa = 7.16MNPAPLYY8 pKa = 9.26LVPRR12 pKa = 11.84TPCEE16 pKa = 3.82KK17 pKa = 10.88YY18 pKa = 10.29PLLKK22 pKa = 10.92LLDD25 pKa = 3.85TCGTTPHH32 pKa = 7.21RR33 pKa = 11.84PPPPPRR39 pKa = 11.84AWAPPRR45 pKa = 11.84HH46 pKa = 6.34PPRR49 pKa = 11.84CRR51 pKa = 11.84RR52 pKa = 11.84RR53 pKa = 11.84LISDD57 pKa = 3.3SDD59 pKa = 3.79STEE62 pKa = 4.28TEE64 pKa = 4.13SSSPTQHH71 pKa = 6.98KK72 pKa = 8.58KK73 pKa = 6.32TTTSGWTVLTSGSTVTVTAQKK94 pKa = 10.46QGTTVTVTVHH104 pKa = 6.34LL105 pKa = 4.45

Molecular weight: 11.57 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2344

95

652

334.9

37.35

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.911 ± 0.527

2.602 ± 0.733

5.546 ± 0.344

5.674 ± 0.845

3.498 ± 0.482

6.527 ± 0.406

2.73 ± 0.485

4.096 ± 0.566

4.65 ± 0.561

8.02 ± 0.462

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.664 ± 0.229

2.858 ± 0.328

6.869 ± 1.259

4.906 ± 0.562

5.674 ± 0.17

7.338 ± 0.728

7.978 ± 0.848

7.082 ± 0.502

1.664 ± 0.376

3.712 ± 0.312
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski