Amino acid dipepetide frequency for Candidatus Magnetoglobus multicellularis str. Araruama

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.74AlaAla: 3.74 ± 0.045	0.843AlaCys: 0.843 ± 0.019	3.506AlaAsp: 3.506 ± 0.044	3.192AlaGlu: 3.192 ± 0.036	2.819AlaPhe: 2.819 ± 0.032	3.962AlaGly: 3.962 ± 0.046	1.221AlaHis: 1.221 ± 0.022	5.372AlaIle: 5.372 ± 0.049	3.247AlaLys: 3.247 ± 0.044	5.696AlaLeu: 5.696 ± 0.048	1.573AlaMet: 1.573 ± 0.024	3.173AlaAsn: 3.173 ± 0.043	1.909AlaPro: 1.909 ± 0.026	2.248AlaGln: 2.248 ± 0.028	2.48AlaArg: 2.48 ± 0.034	4.476AlaSer: 4.476 ± 0.05	3.252AlaThr: 3.252 ± 0.046	3.541AlaVal: 3.541 ± 0.034	0.74AlaTrp: 0.74 ± 0.022	2.423AlaTyr: 2.423 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.649CysAla: 0.649 ± 0.016	0.186CysCys: 0.186 ± 0.008	0.661CysAsp: 0.661 ± 0.017	0.629CysGlu: 0.629 ± 0.016	0.658CysPhe: 0.658 ± 0.014	0.839CysGly: 0.839 ± 0.021	0.393CysHis: 0.393 ± 0.013	0.978CysIle: 0.978 ± 0.019	0.663CysLys: 0.663 ± 0.015	1.177CysLeu: 1.177 ± 0.021	0.324CysMet: 0.324 ± 0.01	0.591CysAsn: 0.591 ± 0.015	0.557CysPro: 0.557 ± 0.016	0.59CysGln: 0.59 ± 0.014	0.518CysArg: 0.518 ± 0.013	0.796CysSer: 0.796 ± 0.017	0.525CysThr: 0.525 ± 0.015	0.65CysVal: 0.65 ± 0.014	0.132CysTrp: 0.132 ± 0.006	0.477CysTyr: 0.477 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.847AspAla: 3.847 ± 0.04	0.687AspCys: 0.687 ± 0.018	3.93AspAsp: 3.93 ± 0.055	3.542AspGlu: 3.542 ± 0.037	2.81AspPhe: 2.81 ± 0.031	4.173AspGly: 4.173 ± 0.064	1.513AspHis: 1.513 ± 0.023	6.369AspIle: 6.369 ± 0.056	3.235AspLys: 3.235 ± 0.038	5.435AspLeu: 5.435 ± 0.056	1.451AspMet: 1.451 ± 0.025	3.931AspAsn: 3.931 ± 0.051	2.498AspPro: 2.498 ± 0.038	2.781AspGln: 2.781 ± 0.035	2.324AspArg: 2.324 ± 0.029	4.076AspSer: 4.076 ± 0.046	3.575AspThr: 3.575 ± 0.046	3.117AspVal: 3.117 ± 0.033	0.753AspTrp: 0.753 ± 0.016	2.745AspTyr: 2.745 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	3.184GluAla: 3.184 ± 0.031	0.581GluCys: 0.581 ± 0.015	2.963GluAsp: 2.963 ± 0.039	2.881GluGlu: 2.881 ± 0.042	2.225GluPhe: 2.225 ± 0.026	2.726GluGly: 2.726 ± 0.03	1.022GluHis: 1.022 ± 0.02	5.721GluIle: 5.721 ± 0.043	5.046GluLys: 5.046 ± 0.061	5.087GluLeu: 5.087 ± 0.054	1.658GluMet: 1.658 ± 0.025	4.264GluAsn: 4.264 ± 0.039	1.723GluPro: 1.723 ± 0.029	2.316GluGln: 2.316 ± 0.035	2.292GluArg: 2.292 ± 0.035	4.028GluSer: 4.028 ± 0.044	3.755GluThr: 3.755 ± 0.033	2.639GluVal: 2.639 ± 0.037	0.701GluTrp: 0.701 ± 0.015	2.172GluTyr: 2.172 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	2.393PheAla: 2.393 ± 0.027	0.595PheCys: 0.595 ± 0.015	3.172PheAsp: 3.172 ± 0.035	2.748PheGlu: 2.748 ± 0.031	2.139PhePhe: 2.139 ± 0.03	2.494PheGly: 2.494 ± 0.03	1.114PheHis: 1.114 ± 0.022	3.592PheIle: 3.592 ± 0.039	2.618PheLys: 2.618 ± 0.034	3.706PheLeu: 3.706 ± 0.048	1.091PheMet: 1.091 ± 0.017	2.492PheAsn: 2.492 ± 0.031	1.558PhePro: 1.558 ± 0.027	2.054PheGln: 2.054 ± 0.031	1.637PheArg: 1.637 ± 0.026	3.963PheSer: 3.963 ± 0.037	2.732PheThr: 2.732 ± 0.041	2.533PheVal: 2.533 ± 0.028	0.486PheTrp: 0.486 ± 0.012	1.833PheTyr: 1.833 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	3.371GlyAla: 3.371 ± 0.045	0.756GlyCys: 0.756 ± 0.019	3.627GlyAsp: 3.627 ± 0.053	3.103GlyGlu: 3.103 ± 0.037	2.746GlyPhe: 2.746 ± 0.031	3.703GlyGly: 3.703 ± 0.064	1.368GlyHis: 1.368 ± 0.024	5.212GlyIle: 5.212 ± 0.047	4.122GlyLys: 4.122 ± 0.046	5.109GlyLeu: 5.109 ± 0.052	1.598GlyMet: 1.598 ± 0.024	3.835GlyAsn: 3.835 ± 0.061	1.448GlyPro: 1.448 ± 0.025	2.526GlyGln: 2.526 ± 0.039	2.267GlyArg: 2.267 ± 0.028	4.177GlySer: 4.177 ± 0.066	3.986GlyThr: 3.986 ± 0.068	3.262GlyVal: 3.262 ± 0.036	0.746GlyTrp: 0.746 ± 0.016	2.537GlyTyr: 2.537 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	1.383HisAla: 1.383 ± 0.021	0.332HisCys: 0.332 ± 0.011	1.163HisAsp: 1.163 ± 0.019	1.198HisGlu: 1.198 ± 0.022	1.198HisPhe: 1.198 ± 0.021	1.213HisGly: 1.213 ± 0.022	0.662HisHis: 0.662 ± 0.015	1.978HisIle: 1.978 ± 0.026	1.136HisLys: 1.136 ± 0.02	2.344HisLeu: 2.344 ± 0.032	0.565HisMet: 0.565 ± 0.016	1.046HisAsn: 1.046 ± 0.018	1.112HisPro: 1.112 ± 0.021	1.007HisGln: 1.007 ± 0.019	0.876HisArg: 0.876 ± 0.019	1.543HisSer: 1.543 ± 0.024	1.16HisThr: 1.16 ± 0.023	1.264HisVal: 1.264 ± 0.02	0.292HisTrp: 0.292 ± 0.01	1.015HisTyr: 1.015 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.467IleAla: 5.467 ± 0.043	1.095IleCys: 1.095 ± 0.019	6.055IleAsp: 6.055 ± 0.046	5.399IleGlu: 5.399 ± 0.046	3.622IlePhe: 3.622 ± 0.035	4.428IleGly: 4.428 ± 0.043	2.232IleHis: 2.232 ± 0.029	6.74IleIle: 6.74 ± 0.054	5.526IleLys: 5.526 ± 0.051	6.978IleLeu: 6.978 ± 0.051	1.725IleMet: 1.725 ± 0.023	5.06IleAsn: 5.06 ± 0.049	3.745IlePro: 3.745 ± 0.041	4.339IleGln: 4.339 ± 0.047	3.426IleArg: 3.426 ± 0.042	7.439IleSer: 7.439 ± 0.062	5.512IleThr: 5.512 ± 0.067	4.962IleVal: 4.962 ± 0.044	0.859IleTrp: 0.859 ± 0.019	3.2IleTyr: 3.2 ± 0.043	0.001IleXaa: 0.001 ± 0.0
Lys	3.896LysAla: 3.896 ± 0.04	0.647LysCys: 0.647 ± 0.016	3.815LysAsp: 3.815 ± 0.043	4.095LysGlu: 4.095 ± 0.056	1.981LysPhe: 1.981 ± 0.027	3.642LysGly: 3.642 ± 0.041	1.373LysHis: 1.373 ± 0.027	5.483LysIle: 5.483 ± 0.058	5.312LysLys: 5.312 ± 0.073	4.959LysLeu: 4.959 ± 0.055	1.692LysMet: 1.692 ± 0.028	4.356LysAsn: 4.356 ± 0.043	2.342LysPro: 2.342 ± 0.027	3.027LysGln: 3.027 ± 0.043	2.85LysArg: 2.85 ± 0.038	4.192LysSer: 4.192 ± 0.041	4.084LysThr: 4.084 ± 0.037	3.095LysVal: 3.095 ± 0.034	0.729LysTrp: 0.729 ± 0.017	2.424LysTyr: 2.424 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	5.146LeuAla: 5.146 ± 0.055	1.081LeuCys: 1.081 ± 0.022	5.134LeuAsp: 5.134 ± 0.053	5.065LeuGlu: 5.065 ± 0.044	4.231LeuPhe: 4.231 ± 0.047	4.338LeuGly: 4.338 ± 0.046	1.659LeuHis: 1.659 ± 0.029	7.188LeuIle: 7.188 ± 0.064	6.624LeuLys: 6.624 ± 0.059	7.521LeuLeu: 7.521 ± 0.082	2.168LeuMet: 2.168 ± 0.03	5.357LeuAsn: 5.357 ± 0.047	3.831LeuPro: 3.831 ± 0.039	3.013LeuGln: 3.013 ± 0.034	3.166LeuArg: 3.166 ± 0.04	7.762LeuSer: 7.762 ± 0.058	6.026LeuThr: 6.026 ± 0.068	4.271LeuVal: 4.271 ± 0.044	0.912LeuTrp: 0.912 ± 0.019	3.13LeuTyr: 3.13 ± 0.038	0.001LeuXaa: 0.001 ± 0.0
Met	1.772MetAla: 1.772 ± 0.03	0.217MetCys: 0.217 ± 0.009	1.659MetAsp: 1.659 ± 0.023	1.257MetGlu: 1.257 ± 0.021	0.847MetPhe: 0.847 ± 0.016	1.579MetGly: 1.579 ± 0.026	0.487MetHis: 0.487 ± 0.015	2.233MetIle: 2.233 ± 0.031	1.841MetLys: 1.841 ± 0.027	1.952MetLeu: 1.952 ± 0.028	0.625MetMet: 0.625 ± 0.015	1.639MetAsn: 1.639 ± 0.024	1.197MetPro: 1.197 ± 0.025	0.858MetGln: 0.858 ± 0.018	0.929MetArg: 0.929 ± 0.019	1.591MetSer: 1.591 ± 0.022	1.57MetThr: 1.57 ± 0.022	1.368MetVal: 1.368 ± 0.022	0.175MetTrp: 0.175 ± 0.007	0.655MetTyr: 0.655 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.865AsnAla: 3.865 ± 0.043	0.713AsnCys: 0.713 ± 0.017	4.081AsnAsp: 4.081 ± 0.056	3.442AsnGlu: 3.442 ± 0.038	2.242AsnPhe: 2.242 ± 0.035	3.896AsnGly: 3.896 ± 0.061	1.419AsnHis: 1.419 ± 0.023	5.424AsnIle: 5.424 ± 0.05	3.528AsnLys: 3.528 ± 0.036	4.837AsnLeu: 4.837 ± 0.051	1.428AsnMet: 1.428 ± 0.021	3.99AsnAsn: 3.99 ± 0.056	2.489AsnPro: 2.489 ± 0.033	3.002AsnGln: 3.002 ± 0.029	2.262AsnArg: 2.262 ± 0.029	3.461AsnSer: 3.461 ± 0.043	3.359AsnThr: 3.359 ± 0.042	3.092AsnVal: 3.092 ± 0.034	0.734AsnTrp: 0.734 ± 0.019	2.237AsnTyr: 2.237 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	1.96ProAla: 1.96 ± 0.031	0.399ProCys: 0.399 ± 0.012	3.343ProAsp: 3.343 ± 0.038	3.212ProGlu: 3.212 ± 0.041	1.91ProPhe: 1.91 ± 0.028	2.481ProGly: 2.481 ± 0.038	0.764ProHis: 0.764 ± 0.017	2.858ProIle: 2.858 ± 0.029	2.132ProLys: 2.132 ± 0.031	3.292ProLeu: 3.292 ± 0.037	0.863ProMet: 0.863 ± 0.019	1.821ProAsn: 1.821 ± 0.026	1.593ProPro: 1.593 ± 0.029	1.461ProGln: 1.461 ± 0.025	1.002ProArg: 1.002 ± 0.016	2.373ProSer: 2.373 ± 0.029	1.821ProThr: 1.821 ± 0.029	3.157ProVal: 3.157 ± 0.039	0.367ProTrp: 0.367 ± 0.01	1.442ProTyr: 1.442 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	2.745GlnAla: 2.745 ± 0.03	0.463GlnCys: 0.463 ± 0.013	1.991GlnAsp: 1.991 ± 0.025	2.219GlnGlu: 2.219 ± 0.03	1.927GlnPhe: 1.927 ± 0.024	2.108GlnGly: 2.108 ± 0.026	0.843GlnHis: 0.843 ± 0.019	3.588GlnIle: 3.588 ± 0.037	3.369GlnLys: 3.369 ± 0.046	4.226GlnLeu: 4.226 ± 0.041	1.229GlnMet: 1.229 ± 0.02	2.579GlnAsn: 2.579 ± 0.03	1.466GlnPro: 1.466 ± 0.02	1.744GlnGln: 1.744 ± 0.028	1.534GlnArg: 1.534 ± 0.026	3.334GlnSer: 3.334 ± 0.034	2.869GlnThr: 2.869 ± 0.039	2.353GlnVal: 2.353 ± 0.031	0.691GlnTrp: 0.691 ± 0.014	1.747GlnTyr: 1.747 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	1.969ArgAla: 1.969 ± 0.029	0.438ArgCys: 0.438 ± 0.013	1.885ArgAsp: 1.885 ± 0.027	2.023ArgGlu: 2.023 ± 0.033	2.036ArgPhe: 2.036 ± 0.033	1.732ArgGly: 1.732 ± 0.023	0.917ArgHis: 0.917 ± 0.02	3.646ArgIle: 3.646 ± 0.037	2.692ArgLys: 2.692 ± 0.038	4.102ArgLeu: 4.102 ± 0.042	1.118ArgMet: 1.118 ± 0.018	2.072ArgAsn: 2.072 ± 0.027	1.316ArgPro: 1.316 ± 0.023	1.761ArgGln: 1.761 ± 0.03	1.589ArgArg: 1.589 ± 0.028	2.397ArgSer: 2.397 ± 0.032	1.856ArgThr: 1.856 ± 0.023	2.151ArgVal: 2.151 ± 0.03	0.486ArgTrp: 0.486 ± 0.013	1.642ArgTyr: 1.642 ± 0.028	0.0ArgXaa: 0.0 ± 0.0
Ser	4.055SerAla: 4.055 ± 0.046	0.811SerCys: 0.811 ± 0.017	5.215SerAsp: 5.215 ± 0.058	4.275SerGlu: 4.275 ± 0.039	3.689SerPhe: 3.689 ± 0.037	5.834SerGly: 5.834 ± 0.074	1.558SerHis: 1.558 ± 0.021	6.538SerIle: 6.538 ± 0.054	4.103SerLys: 4.103 ± 0.039	6.408SerLeu: 6.408 ± 0.047	1.64SerMet: 1.64 ± 0.027	4.207SerAsn: 4.207 ± 0.054	2.785SerPro: 2.785 ± 0.033	3.083SerGln: 3.083 ± 0.035	2.366SerArg: 2.366 ± 0.028	5.238SerSer: 5.238 ± 0.071	3.831SerThr: 3.831 ± 0.05	4.287SerVal: 4.287 ± 0.047	0.85SerTrp: 0.85 ± 0.018	2.59SerTyr: 2.59 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	3.778ThrAla: 3.778 ± 0.049	0.703ThrCys: 0.703 ± 0.015	3.966ThrAsp: 3.966 ± 0.049	2.941ThrGlu: 2.941 ± 0.032	2.807ThrPhe: 2.807 ± 0.04	4.477ThrGly: 4.477 ± 0.047	1.327ThrHis: 1.327 ± 0.018	6.227ThrIle: 6.227 ± 0.076	2.726ThrLys: 2.726 ± 0.028	5.255ThrLeu: 5.255 ± 0.05	1.199ThrMet: 1.199 ± 0.021	3.1ThrAsn: 3.1 ± 0.037	2.708ThrPro: 2.708 ± 0.036	2.431ThrGln: 2.431 ± 0.033	1.918ThrArg: 1.918 ± 0.028	4.065ThrSer: 4.065 ± 0.058	3.376ThrThr: 3.376 ± 0.058	4.021ThrVal: 4.021 ± 0.07	0.644ThrTrp: 0.644 ± 0.015	2.166ThrTyr: 2.166 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	3.185ValAla: 3.185 ± 0.039	0.762ValCys: 0.762 ± 0.017	3.553ValAsp: 3.553 ± 0.038	3.015ValGlu: 3.015 ± 0.035	2.667ValPhe: 2.667 ± 0.031	2.837ValGly: 2.837 ± 0.036	1.175ValHis: 1.175 ± 0.022	4.623ValIle: 4.623 ± 0.039	3.37ValLys: 3.37 ± 0.034	4.847ValLeu: 4.847 ± 0.043	1.361ValMet: 1.361 ± 0.025	3.376ValAsn: 3.376 ± 0.046	2.076ValPro: 2.076 ± 0.029	2.14ValGln: 2.14 ± 0.029	2.243ValArg: 2.243 ± 0.028	4.898ValSer: 4.898 ± 0.05	3.472ValThr: 3.472 ± 0.053	3.211ValVal: 3.211 ± 0.04	0.689ValTrp: 0.689 ± 0.02	2.177ValTyr: 2.177 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	0.7TrpAla: 0.7 ± 0.018	0.138TrpCys: 0.138 ± 0.006	0.671TrpAsp: 0.671 ± 0.015	0.652TrpGlu: 0.652 ± 0.017	0.47TrpPhe: 0.47 ± 0.012	0.858TrpGly: 0.858 ± 0.029	0.349TrpHis: 0.349 ± 0.011	1.028TrpIle: 1.028 ± 0.018	0.721TrpLys: 0.721 ± 0.016	1.016TrpLeu: 1.016 ± 0.019	0.302TrpMet: 0.302 ± 0.008	0.664TrpAsn: 0.664 ± 0.018	0.325TrpPro: 0.325 ± 0.01	0.616TrpGln: 0.616 ± 0.015	0.473TrpArg: 0.473 ± 0.013	0.81TrpSer: 0.81 ± 0.019	0.649TrpThr: 0.649 ± 0.015	0.65TrpVal: 0.65 ± 0.014	0.126TrpTrp: 0.126 ± 0.007	0.424TrpTyr: 0.424 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.309TyrAla: 2.309 ± 0.03	0.544TyrCys: 0.544 ± 0.014	2.401TyrAsp: 2.401 ± 0.034	2.097TyrGlu: 2.097 ± 0.028	1.928TyrPhe: 1.928 ± 0.027	2.18TyrGly: 2.18 ± 0.033	1.092TyrHis: 1.092 ± 0.018	3.011TyrIle: 3.011 ± 0.037	1.983TyrLys: 1.983 ± 0.031	3.677TyrLeu: 3.677 ± 0.039	0.836TyrMet: 0.836 ± 0.017	1.946TyrAsn: 1.946 ± 0.03	1.574TyrPro: 1.574 ± 0.022	2.028TyrGln: 2.028 ± 0.033	1.678TyrArg: 1.678 ± 0.026	2.745TyrSer: 2.745 ± 0.038	2.423TyrThr: 2.423 ± 0.041	2.052TyrVal: 2.052 ± 0.029	0.531TyrTrp: 0.531 ± 0.014	1.841TyrTyr: 1.841 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9976 proteins (3167227 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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