Amino acid dipepetide frequency for Wuhan arthropod virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.294AlaAla: 9.294 ± 2.494
0.62AlaCys: 0.62 ± 0.305
4.027AlaAsp: 4.027 ± 1.143
2.169AlaGlu: 2.169 ± 0.681
1.549AlaPhe: 1.549 ± 0.688
6.815AlaGly: 6.815 ± 1.841
2.478AlaHis: 2.478 ± 0.794
4.027AlaIle: 4.027 ± 1.511
7.125AlaLys: 7.125 ± 9.313
5.576AlaLeu: 5.576 ± 0.986
2.169AlaMet: 2.169 ± 0.781
3.717AlaAsn: 3.717 ± 1.198
5.266AlaPro: 5.266 ± 1.773
3.408AlaGln: 3.408 ± 0.831
2.788AlaArg: 2.788 ± 0.289
5.266AlaSer: 5.266 ± 2.01
4.647AlaThr: 4.647 ± 2.507
4.647AlaVal: 4.647 ± 1.201
0.0AlaTrp: 0.0 ± 0.0
1.859AlaTyr: 1.859 ± 0.663
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.929CysCys: 0.929 ± 0.458
0.62CysAsp: 0.62 ± 0.305
0.62CysGlu: 0.62 ± 0.305
1.239CysPhe: 1.239 ± 0.61
1.239CysGly: 1.239 ± 0.61
0.31CysHis: 0.31 ± 0.153
0.31CysIle: 0.31 ± 0.461
2.169CysLys: 2.169 ± 0.674
2.478CysLeu: 2.478 ± 1.221
0.31CysMet: 0.31 ± 0.153
0.0CysAsn: 0.0 ± 0.0
0.929CysPro: 0.929 ± 0.458
0.31CysGln: 0.31 ± 0.153
1.239CysArg: 1.239 ± 0.61
0.929CysSer: 0.929 ± 0.458
0.62CysThr: 0.62 ± 0.372
0.929CysVal: 0.929 ± 0.458
0.0CysTrp: 0.0 ± 0.0
0.929CysTyr: 0.929 ± 0.458
0.0CysXaa: 0.0 ± 0.0
Asp
4.337AspAla: 4.337 ± 1.133
1.239AspCys: 1.239 ± 0.61
4.647AspAsp: 4.647 ± 1.457
4.957AspGlu: 4.957 ± 1.434
4.647AspPhe: 4.647 ± 1.32
2.788AspGly: 2.788 ± 0.788
1.239AspHis: 1.239 ± 0.359
2.788AspIle: 2.788 ± 0.929
3.717AspLys: 3.717 ± 0.829
6.815AspLeu: 6.815 ± 2.121
1.239AspMet: 1.239 ± 0.61
2.788AspAsn: 2.788 ± 0.959
4.957AspPro: 4.957 ± 0.932
0.929AspGln: 0.929 ± 0.824
1.859AspArg: 1.859 ± 0.553
3.717AspSer: 3.717 ± 1.105
3.098AspThr: 3.098 ± 1.104
3.098AspVal: 3.098 ± 0.274
0.31AspTrp: 0.31 ± 0.153
1.239AspTyr: 1.239 ± 0.61
0.0AspXaa: 0.0 ± 0.0
Glu
3.717GluAla: 3.717 ± 0.88
0.62GluCys: 0.62 ± 0.305
2.788GluAsp: 2.788 ± 0.374
3.408GluGlu: 3.408 ± 0.999
2.478GluPhe: 2.478 ± 0.717
2.788GluGly: 2.788 ± 0.374
0.929GluHis: 0.929 ± 0.332
1.859GluIle: 1.859 ± 0.916
2.478GluLys: 2.478 ± 1.237
4.957GluLeu: 4.957 ± 1.996
1.859GluMet: 1.859 ± 0.916
2.478GluAsn: 2.478 ± 1.221
3.408GluPro: 3.408 ± 1.213
3.717GluGln: 3.717 ± 1.105
1.549GluArg: 1.549 ± 0.456
3.408GluSer: 3.408 ± 1.343
1.859GluThr: 1.859 ± 0.108
3.408GluVal: 3.408 ± 1.027
1.239GluTrp: 1.239 ± 0.61
1.549GluTyr: 1.549 ± 0.44
0.0GluXaa: 0.0 ± 0.0
Phe
1.549PheAla: 1.549 ± 0.688
1.239PheCys: 1.239 ± 0.359
3.717PheAsp: 3.717 ± 0.613
3.408PheGlu: 3.408 ± 0.987
2.169PhePhe: 2.169 ± 0.674
3.098PheGly: 3.098 ± 1.0
0.62PheHis: 0.62 ± 0.372
2.788PheIle: 2.788 ± 0.995
3.098PheLys: 3.098 ± 0.525
3.408PheLeu: 3.408 ± 0.677
1.239PheMet: 1.239 ± 0.61
2.478PheAsn: 2.478 ± 1.221
2.169PhePro: 2.169 ± 0.089
0.929PheGln: 0.929 ± 0.332
0.0PheArg: 0.0 ± 0.0
3.408PheSer: 3.408 ± 0.336
4.957PheThr: 4.957 ± 0.746
3.717PheVal: 3.717 ± 1.105
0.929PheTrp: 0.929 ± 0.458
1.239PheTyr: 1.239 ± 1.282
0.0PheXaa: 0.0 ± 0.0
Gly
4.337GlyAla: 4.337 ± 1.524
0.929GlyCys: 0.929 ± 0.458
3.408GlyAsp: 3.408 ± 0.987
3.098GlyGlu: 3.098 ± 1.295
4.337GlyPhe: 4.337 ± 1.476
3.408GlyGly: 3.408 ± 0.831
1.239GlyHis: 1.239 ± 0.359
2.478GlyIle: 2.478 ± 0.373
4.647GlyLys: 4.647 ± 0.575
5.266GlyLeu: 5.266 ± 0.906
1.239GlyMet: 1.239 ± 0.401
1.549GlyAsn: 1.549 ± 0.841
1.859GlyPro: 1.859 ± 0.553
3.098GlyGln: 3.098 ± 1.104
0.929GlyArg: 0.929 ± 0.458
4.027GlySer: 4.027 ± 1.143
4.337GlyThr: 4.337 ± 1.359
4.957GlyVal: 4.957 ± 0.526
0.929GlyTrp: 0.929 ± 0.458
3.098GlyTyr: 3.098 ± 0.525
0.0GlyXaa: 0.0 ± 0.0
His
1.549HisAla: 1.549 ± 1.192
0.62HisCys: 0.62 ± 0.305
0.929HisAsp: 0.929 ± 0.458
1.549HisGlu: 1.549 ± 0.763
0.929HisPhe: 0.929 ± 0.332
2.788HisGly: 2.788 ± 0.959
0.62HisHis: 0.62 ± 0.305
0.31HisIle: 0.31 ± 0.153
1.859HisLys: 1.859 ± 0.624
2.788HisLeu: 2.788 ± 0.845
0.0HisMet: 0.0 ± 0.0
0.31HisAsn: 0.31 ± 0.153
0.31HisPro: 0.31 ± 0.461
0.62HisGln: 0.62 ± 0.305
0.62HisArg: 0.62 ± 0.372
1.549HisSer: 1.549 ± 0.763
0.0HisThr: 0.0 ± 0.0
1.859HisVal: 1.859 ± 0.663
0.929HisTrp: 0.929 ± 0.458
1.239HisTyr: 1.239 ± 0.399
0.0HisXaa: 0.0 ± 0.0
Ile
4.957IleAla: 4.957 ± 1.251
0.31IleCys: 0.31 ± 0.153
6.196IleAsp: 6.196 ± 1.027
3.408IleGlu: 3.408 ± 1.027
1.239IlePhe: 1.239 ± 0.61
1.859IleGly: 1.859 ± 0.663
1.549IleHis: 1.549 ± 0.688
1.239IleIle: 1.239 ± 0.61
3.408IleLys: 3.408 ± 1.25
4.957IleLeu: 4.957 ± 1.635
0.62IleMet: 0.62 ± 0.372
2.788IleAsn: 2.788 ± 0.374
2.169IlePro: 2.169 ± 1.646
2.478IleGln: 2.478 ± 0.373
2.169IleArg: 2.169 ± 0.665
2.169IleSer: 2.169 ± 0.089
2.788IleThr: 2.788 ± 1.096
2.478IleVal: 2.478 ± 0.717
0.0IleTrp: 0.0 ± 0.0
4.647IleTyr: 4.647 ± 0.942
0.0IleXaa: 0.0 ± 0.0
Lys
4.647LysAla: 4.647 ± 5.02
0.929LysCys: 0.929 ± 0.458
2.478LysAsp: 2.478 ± 0.794
2.788LysGlu: 2.788 ± 1.2
1.549LysPhe: 1.549 ± 1.443
4.337LysGly: 4.337 ± 2.583
2.478LysHis: 2.478 ± 1.237
5.576LysIle: 5.576 ± 1.087
5.266LysLys: 5.266 ± 2.943
7.435LysLeu: 7.435 ± 0.901
2.169LysMet: 2.169 ± 1.068
3.717LysAsn: 3.717 ± 1.358
6.196LysPro: 6.196 ± 4.521
1.549LysGln: 1.549 ± 0.456
2.169LysArg: 2.169 ± 0.653
5.266LysSer: 5.266 ± 2.973
3.098LysThr: 3.098 ± 0.455
8.055LysVal: 8.055 ± 4.818
0.929LysTrp: 0.929 ± 0.4
3.098LysTyr: 3.098 ± 1.181
0.0LysXaa: 0.0 ± 0.0
Leu
8.364LeuAla: 8.364 ± 0.771
1.239LeuCys: 1.239 ± 0.61
5.886LeuAsp: 5.886 ± 1.447
4.957LeuGlu: 4.957 ± 1.0
4.337LeuPhe: 4.337 ± 1.362
4.957LeuGly: 4.957 ± 0.602
2.169LeuHis: 2.169 ± 1.068
5.266LeuIle: 5.266 ± 0.88
6.815LeuLys: 6.815 ± 1.544
4.957LeuLeu: 4.957 ± 0.746
1.859LeuMet: 1.859 ± 0.553
2.478LeuAsn: 2.478 ± 0.717
4.027LeuPro: 4.027 ± 0.573
2.478LeuGln: 2.478 ± 0.717
4.647LeuArg: 4.647 ± 0.88
4.957LeuSer: 4.957 ± 0.526
5.886LeuThr: 5.886 ± 0.606
4.957LeuVal: 4.957 ± 0.602
0.62LeuTrp: 0.62 ± 0.305
3.717LeuTyr: 3.717 ± 1.076
0.0LeuXaa: 0.0 ± 0.0
Met
1.859MetAla: 1.859 ± 0.108
0.31MetCys: 0.31 ± 0.153
2.478MetAsp: 2.478 ± 0.717
0.929MetGlu: 0.929 ± 0.458
1.549MetPhe: 1.549 ± 0.763
1.859MetGly: 1.859 ± 1.43
0.62MetHis: 0.62 ± 0.372
0.929MetIle: 0.929 ± 0.458
2.169MetLys: 2.169 ± 1.068
1.549MetLeu: 1.549 ± 0.456
1.549MetMet: 1.549 ± 0.763
0.31MetAsn: 0.31 ± 0.153
1.239MetPro: 1.239 ± 0.61
0.0MetGln: 0.0 ± 0.0
0.62MetArg: 0.62 ± 0.305
1.549MetSer: 1.549 ± 0.688
1.859MetThr: 1.859 ± 0.916
0.929MetVal: 0.929 ± 0.4
0.0MetTrp: 0.0 ± 0.0
0.31MetTyr: 0.31 ± 0.461
0.0MetXaa: 0.0 ± 0.0
Asn
4.027AsnAla: 4.027 ± 0.602
0.929AsnCys: 0.929 ± 0.824
1.239AsnAsp: 1.239 ± 0.61
1.859AsnGlu: 1.859 ± 0.55
3.098AsnPhe: 3.098 ± 0.88
0.62AsnGly: 0.62 ± 0.454
0.31AsnHis: 0.31 ± 0.153
2.478AsnIle: 2.478 ± 0.798
2.169AsnLys: 2.169 ± 1.291
2.478AsnLeu: 2.478 ± 0.225
1.239AsnMet: 1.239 ± 0.907
2.478AsnAsn: 2.478 ± 0.554
4.027AsnPro: 4.027 ± 0.541
1.549AsnGln: 1.549 ± 0.25
2.169AsnArg: 2.169 ± 0.786
3.717AsnSer: 3.717 ± 1.459
4.647AsnThr: 4.647 ± 0.749
4.027AsnVal: 4.027 ± 1.984
0.62AsnTrp: 0.62 ± 0.305
2.788AsnTyr: 2.788 ± 0.788
0.0AsnXaa: 0.0 ± 0.0
Pro
3.408ProAla: 3.408 ± 0.933
1.239ProCys: 1.239 ± 0.359
2.788ProAsp: 2.788 ± 0.959
4.337ProGlu: 4.337 ± 1.653
1.859ProPhe: 1.859 ± 0.553
2.169ProGly: 2.169 ± 0.491
0.62ProHis: 0.62 ± 0.372
4.337ProIle: 4.337 ± 0.404
6.196ProLys: 6.196 ± 1.636
5.266ProLeu: 5.266 ± 0.998
1.549ProMet: 1.549 ± 0.763
3.408ProAsn: 3.408 ± 0.831
7.435ProPro: 7.435 ± 1.095
1.859ProGln: 1.859 ± 0.108
1.239ProArg: 1.239 ± 0.401
2.788ProSer: 2.788 ± 1.2
5.576ProThr: 5.576 ± 2.895
5.576ProVal: 5.576 ± 1.296
0.929ProTrp: 0.929 ± 0.458
1.239ProTyr: 1.239 ± 1.282
0.0ProXaa: 0.0 ± 0.0
Gln
1.859GlnAla: 1.859 ± 0.769
0.929GlnCys: 0.929 ± 0.458
1.239GlnAsp: 1.239 ± 0.61
1.239GlnGlu: 1.239 ± 0.61
1.549GlnPhe: 1.549 ± 0.688
0.62GlnGly: 0.62 ± 0.922
0.0GlnHis: 0.0 ± 0.0
3.098GlnIle: 3.098 ± 0.274
2.788GlnLys: 2.788 ± 1.2
3.098GlnLeu: 3.098 ± 1.0
1.239GlnMet: 1.239 ± 0.359
1.859GlnAsn: 1.859 ± 0.108
2.788GlnPro: 2.788 ± 0.959
0.62GlnGln: 0.62 ± 0.305
1.859GlnArg: 1.859 ± 0.624
3.098GlnSer: 3.098 ± 0.736
1.549GlnThr: 1.549 ± 1.192
2.788GlnVal: 2.788 ± 1.129
0.0GlnTrp: 0.0 ± 0.0
0.929GlnTyr: 0.929 ± 0.458
0.0GlnXaa: 0.0 ± 0.0
Arg
2.169ArgAla: 2.169 ± 0.665
0.62ArgCys: 0.62 ± 0.305
3.098ArgAsp: 3.098 ± 1.104
1.239ArgGlu: 1.239 ± 0.907
1.859ArgPhe: 1.859 ± 0.108
1.549ArgGly: 1.549 ± 0.763
0.0ArgHis: 0.0 ± 0.0
1.239ArgIle: 1.239 ± 0.399
3.098ArgLys: 3.098 ± 0.913
2.788ArgLeu: 2.788 ± 0.788
0.31ArgMet: 0.31 ± 0.153
3.098ArgAsn: 3.098 ± 0.525
2.478ArgPro: 2.478 ± 0.802
1.859ArgGln: 1.859 ± 0.624
3.098ArgArg: 3.098 ± 0.455
3.408ArgSer: 3.408 ± 1.027
1.239ArgThr: 1.239 ± 0.61
2.478ArgVal: 2.478 ± 0.794
0.0ArgTrp: 0.0 ± 0.0
1.549ArgTyr: 1.549 ± 0.897
0.0ArgXaa: 0.0 ± 0.0
Ser
7.745SerAla: 7.745 ± 3.508
1.239SerCys: 1.239 ± 0.61
4.027SerAsp: 4.027 ± 1.546
1.549SerGlu: 1.549 ± 0.763
2.788SerPhe: 2.788 ± 0.374
5.266SerGly: 5.266 ± 1.499
1.549SerHis: 1.549 ± 0.44
3.098SerIle: 3.098 ± 1.375
1.239SerLys: 1.239 ± 0.907
7.125SerLeu: 7.125 ± 0.148
1.239SerMet: 1.239 ± 0.399
4.027SerAsn: 4.027 ± 1.996
2.788SerPro: 2.788 ± 1.374
1.239SerGln: 1.239 ± 0.399
4.647SerArg: 4.647 ± 0.575
8.674SerSer: 8.674 ± 0.825
6.196SerThr: 6.196 ± 1.473
2.788SerVal: 2.788 ± 1.096
0.62SerTrp: 0.62 ± 0.305
1.239SerTyr: 1.239 ± 0.359
0.0SerXaa: 0.0 ± 0.0
Thr
6.196ThrAla: 6.196 ± 1.602
0.62ThrCys: 0.62 ± 0.305
3.717ThrAsp: 3.717 ± 0.829
1.859ThrGlu: 1.859 ± 0.108
3.098ThrPhe: 3.098 ± 1.375
4.337ThrGly: 4.337 ± 0.629
0.929ThrHis: 0.929 ± 0.332
2.788ThrIle: 2.788 ± 0.834
6.506ThrLys: 6.506 ± 5.78
4.647ThrLeu: 4.647 ± 1.384
0.929ThrMet: 0.929 ± 0.426
4.027ThrAsn: 4.027 ± 2.051
4.647ThrPro: 4.647 ± 2.035
1.859ThrGln: 1.859 ± 1.115
1.239ThrArg: 1.239 ± 0.359
4.957ThrSer: 4.957 ± 1.434
6.815ThrThr: 6.815 ± 3.631
3.717ThrVal: 3.717 ± 0.217
1.239ThrTrp: 1.239 ± 0.743
2.788ThrTyr: 2.788 ± 0.788
0.0ThrXaa: 0.0 ± 0.0
Val
5.266ValAla: 5.266 ± 3.66
0.929ValCys: 0.929 ± 0.458
3.717ValAsp: 3.717 ± 1.076
4.647ValGlu: 4.647 ± 2.289
3.408ValPhe: 3.408 ± 1.194
6.506ValGly: 6.506 ± 1.491
0.31ValHis: 0.31 ± 0.153
4.957ValIle: 4.957 ± 1.425
6.196ValLys: 6.196 ± 3.891
5.576ValLeu: 5.576 ± 0.336
0.929ValMet: 0.929 ± 0.281
2.788ValAsn: 2.788 ± 1.096
4.957ValPro: 4.957 ± 0.602
2.169ValGln: 2.169 ± 0.674
2.478ValArg: 2.478 ± 1.221
4.337ValSer: 4.337 ± 0.629
2.788ValThr: 2.788 ± 1.652
5.576ValVal: 5.576 ± 2.82
0.31ValTrp: 0.31 ± 0.153
2.169ValTyr: 2.169 ± 0.681
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.929TrpAsp: 0.929 ± 0.458
0.929TrpGlu: 0.929 ± 0.458
0.62TrpPhe: 0.62 ± 0.305
0.31TrpGly: 0.31 ± 0.153
0.31TrpHis: 0.31 ± 0.153
0.62TrpIle: 0.62 ± 0.305
1.239TrpLys: 1.239 ± 0.401
1.239TrpLeu: 1.239 ± 0.61
0.31TrpMet: 0.31 ± 0.153
0.62TrpAsn: 0.62 ± 0.305
0.31TrpPro: 0.31 ± 0.153
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.31TrpSer: 0.31 ± 0.153
0.929TrpThr: 0.929 ± 0.332
0.929TrpVal: 0.929 ± 0.332
0.0TrpTrp: 0.0 ± 0.0
0.62TrpTyr: 0.62 ± 0.305
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.478TyrAla: 2.478 ± 1.523
0.62TyrCys: 0.62 ± 0.305
2.478TyrAsp: 2.478 ± 0.373
1.549TyrGlu: 1.549 ± 0.25
1.859TyrPhe: 1.859 ± 0.916
1.859TyrGly: 1.859 ± 0.916
3.098TyrHis: 3.098 ± 0.88
1.239TyrIle: 1.239 ± 0.61
1.549TyrLys: 1.549 ± 0.841
2.169TyrLeu: 2.169 ± 1.055
0.31TyrMet: 0.31 ± 0.461
1.549TyrAsn: 1.549 ± 0.688
1.859TyrPro: 1.859 ± 0.553
2.478TyrGln: 2.478 ± 1.198
1.859TyrArg: 1.859 ± 0.553
1.549TyrSer: 1.549 ± 0.763
4.027TyrThr: 4.027 ± 1.7
3.098TyrVal: 3.098 ± 1.0
0.62TyrTrp: 0.62 ± 0.305
3.408TyrTyr: 3.408 ± 1.25
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3229 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski