Amino acid dipepetide frequency for Tacheng Tick Virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.268AlaAla: 7.268 ± 2.72
2.12AlaCys: 2.12 ± 0.212
4.543AlaAsp: 4.543 ± 2.321
3.937AlaGlu: 3.937 ± 0.865
3.028AlaPhe: 3.028 ± 0.934
6.057AlaGly: 6.057 ± 1.58
3.331AlaHis: 3.331 ± 1.398
5.148AlaIle: 5.148 ± 0.359
2.726AlaLys: 2.726 ± 0.478
7.874AlaLeu: 7.874 ± 0.945
2.423AlaMet: 2.423 ± 1.165
2.12AlaAsn: 2.12 ± 2.402
4.24AlaPro: 4.24 ± 1.993
1.211AlaGln: 1.211 ± 0.322
4.24AlaArg: 4.24 ± 0.661
3.331AlaSer: 3.331 ± 0.444
4.543AlaThr: 4.543 ± 0.128
5.451AlaVal: 5.451 ± 0.956
0.909AlaTrp: 0.909 ± 0.493
6.36AlaTyr: 6.36 ± 1.152
0.0AlaXaa: 0.0 ± 0.0
Cys
0.909CysAla: 0.909 ± 0.38
0.303CysCys: 0.303 ± 0.164
0.606CysAsp: 0.606 ± 0.329
0.909CysGlu: 0.909 ± 0.493
0.303CysPhe: 0.303 ± 0.39
1.817CysGly: 1.817 ± 1.351
1.211CysHis: 1.211 ± 0.599
0.606CysIle: 0.606 ± 0.329
0.303CysLys: 0.303 ± 0.164
1.211CysLeu: 1.211 ± 0.355
0.303CysMet: 0.303 ± 0.164
0.909CysAsn: 0.909 ± 0.284
1.514CysPro: 1.514 ± 0.56
0.303CysGln: 0.303 ± 0.523
1.211CysArg: 1.211 ± 0.599
1.211CysSer: 1.211 ± 0.599
0.606CysThr: 0.606 ± 0.299
0.909CysVal: 0.909 ± 0.284
0.0CysTrp: 0.0 ± 0.0
0.909CysTyr: 0.909 ± 0.493
0.0CysXaa: 0.0 ± 0.0
Asp
2.423AspAla: 2.423 ± 0.695
0.303AspCys: 0.303 ± 0.39
4.24AspAsp: 4.24 ± 0.941
1.514AspGlu: 1.514 ± 0.821
2.12AspPhe: 2.12 ± 0.801
1.514AspGly: 1.514 ± 0.97
2.12AspHis: 2.12 ± 0.586
3.331AspIle: 3.331 ± 0.972
1.514AspLys: 1.514 ± 0.173
9.388AspLeu: 9.388 ± 1.562
0.909AspMet: 0.909 ± 0.941
1.211AspAsn: 1.211 ± 0.959
4.24AspPro: 4.24 ± 1.34
2.12AspGln: 2.12 ± 0.586
3.028AspArg: 3.028 ± 0.934
2.12AspSer: 2.12 ± 0.765
2.726AspThr: 2.726 ± 0.49
4.543AspVal: 4.543 ± 1.681
0.909AspTrp: 0.909 ± 0.38
1.211AspTyr: 1.211 ± 0.657
0.0AspXaa: 0.0 ± 0.0
Glu
6.965GluAla: 6.965 ± 1.591
1.211GluCys: 1.211 ± 1.062
3.028GluAsp: 3.028 ± 1.237
2.726GluGlu: 2.726 ± 0.49
1.817GluPhe: 1.817 ± 0.615
3.028GluGly: 3.028 ± 1.137
1.514GluHis: 1.514 ± 0.48
3.937GluIle: 3.937 ± 0.804
1.514GluLys: 1.514 ± 0.48
3.028GluLeu: 3.028 ± 0.687
2.423GluMet: 2.423 ± 0.365
1.211GluAsn: 1.211 ± 0.657
3.331GluPro: 3.331 ± 0.873
2.12GluGln: 2.12 ± 0.212
4.543GluArg: 4.543 ± 0.52
3.331GluSer: 3.331 ± 1.398
3.634GluThr: 3.634 ± 0.477
3.028GluVal: 3.028 ± 0.725
1.514GluTrp: 1.514 ± 0.48
2.12GluTyr: 2.12 ± 0.852
0.0GluXaa: 0.0 ± 0.0
Phe
2.726PheAla: 2.726 ± 2.264
0.303PheCys: 0.303 ± 0.164
1.514PheAsp: 1.514 ± 0.606
2.423PheGlu: 2.423 ± 0.365
1.514PhePhe: 1.514 ± 0.791
3.028PheGly: 3.028 ± 0.498
1.211PheHis: 1.211 ± 0.657
1.817PheIle: 1.817 ± 0.615
0.606PheLys: 0.606 ± 0.329
4.24PheLeu: 4.24 ± 0.941
0.606PheMet: 0.606 ± 0.329
1.514PheAsn: 1.514 ± 0.791
2.423PhePro: 2.423 ± 0.644
2.12PheGln: 2.12 ± 0.622
2.423PheArg: 2.423 ± 0.509
2.726PheSer: 2.726 ± 0.853
3.331PheThr: 3.331 ± 0.444
1.817PheVal: 1.817 ± 0.102
0.0PheTrp: 0.0 ± 0.0
0.909PheTyr: 0.909 ± 0.941
0.0PheXaa: 0.0 ± 0.0
Gly
3.331GlyAla: 3.331 ± 0.881
1.211GlyCys: 1.211 ± 0.599
3.937GlyAsp: 3.937 ± 0.811
3.331GlyGlu: 3.331 ± 0.574
3.634GlyPhe: 3.634 ± 1.013
3.937GlyGly: 3.937 ± 1.168
0.606GlyHis: 0.606 ± 0.329
3.028GlyIle: 3.028 ± 0.994
1.514GlyLys: 1.514 ± 1.45
3.937GlyLeu: 3.937 ± 2.134
1.514GlyMet: 1.514 ± 0.173
2.423GlyAsn: 2.423 ± 0.509
3.331GlyPro: 3.331 ± 1.123
3.028GlyGln: 3.028 ± 0.725
3.634GlyArg: 3.634 ± 1.257
2.423GlySer: 2.423 ± 1.211
2.12GlyThr: 2.12 ± 0.212
4.24GlyVal: 4.24 ± 2.53
0.606GlyTrp: 0.606 ± 0.299
1.211GlyTyr: 1.211 ± 0.4
0.0GlyXaa: 0.0 ± 0.0
His
3.028HisAla: 3.028 ± 0.96
1.514HisCys: 1.514 ± 0.56
0.606HisAsp: 0.606 ± 0.299
1.514HisGlu: 1.514 ± 0.821
0.909HisPhe: 0.909 ± 0.284
2.12HisGly: 2.12 ± 0.308
1.211HisHis: 1.211 ± 0.657
1.514HisIle: 1.514 ± 1.123
1.817HisLys: 1.817 ± 0.102
4.24HisLeu: 4.24 ± 0.102
1.514HisMet: 1.514 ± 0.821
0.909HisAsn: 0.909 ± 0.493
3.634HisPro: 3.634 ± 0.598
0.303HisGln: 0.303 ± 0.164
2.726HisArg: 2.726 ± 0.853
1.514HisSer: 1.514 ± 0.173
2.726HisThr: 2.726 ± 0.853
2.12HisVal: 2.12 ± 0.212
0.303HisTrp: 0.303 ± 0.164
1.211HisTyr: 1.211 ± 0.355
0.0HisXaa: 0.0 ± 0.0
Ile
2.12IleAla: 2.12 ± 0.73
0.0IleCys: 0.0 ± 0.0
3.634IleAsp: 3.634 ± 1.191
3.634IleGlu: 3.634 ± 1.013
1.514IlePhe: 1.514 ± 0.821
2.12IleGly: 2.12 ± 0.826
1.514IleHis: 1.514 ± 0.56
4.24IleIle: 4.24 ± 0.423
2.726IleLys: 2.726 ± 1.025
5.148IleLeu: 5.148 ± 1.701
0.909IleMet: 0.909 ± 0.284
3.331IleAsn: 3.331 ± 0.574
2.726IlePro: 2.726 ± 0.478
3.028IleGln: 3.028 ± 0.949
6.057IleArg: 6.057 ± 1.014
3.634IleSer: 3.634 ± 0.4
5.754IleThr: 5.754 ± 0.762
7.268IleVal: 7.268 ± 1.748
0.909IleTrp: 0.909 ± 0.676
3.937IleTyr: 3.937 ± 1.181
0.0IleXaa: 0.0 ± 0.0
Lys
2.423LysAla: 2.423 ± 0.874
0.303LysCys: 0.303 ± 0.164
1.211LysAsp: 1.211 ± 0.4
3.028LysGlu: 3.028 ± 0.949
2.726LysPhe: 2.726 ± 1.011
1.514LysGly: 1.514 ± 0.48
0.606LysHis: 0.606 ± 0.329
3.634LysIle: 3.634 ± 0.477
2.423LysLys: 2.423 ± 0.92
3.937LysLeu: 3.937 ± 0.289
0.909LysMet: 0.909 ± 0.481
0.909LysAsn: 0.909 ± 0.493
0.606LysPro: 0.606 ± 0.329
1.211LysGln: 1.211 ± 0.854
2.12LysArg: 2.12 ± 0.622
0.606LysSer: 0.606 ± 0.329
2.726LysThr: 2.726 ± 0.525
2.423LysVal: 2.423 ± 0.365
0.0LysTrp: 0.0 ± 0.0
2.12LysTyr: 2.12 ± 0.852
0.0LysXaa: 0.0 ± 0.0
Leu
6.965LeuAla: 6.965 ± 1.068
1.211LeuCys: 1.211 ± 0.355
5.451LeuAsp: 5.451 ± 1.045
6.663LeuGlu: 6.663 ± 0.889
2.12LeuPhe: 2.12 ± 0.212
4.543LeuGly: 4.543 ± 1.002
5.148LeuHis: 5.148 ± 0.437
5.754LeuIle: 5.754 ± 1.73
3.937LeuLys: 3.937 ± 1.176
12.114LeuLeu: 12.114 ± 3.658
1.514LeuMet: 1.514 ± 0.979
2.423LeuAsn: 2.423 ± 0.199
5.451LeuPro: 5.451 ± 1.996
3.937LeuGln: 3.937 ± 0.757
7.268LeuArg: 7.268 ± 0.597
6.057LeuSer: 6.057 ± 1.893
7.874LeuThr: 7.874 ± 0.945
7.268LeuVal: 7.268 ± 0.8
1.211LeuTrp: 1.211 ± 0.4
4.846LeuTyr: 4.846 ± 0.277
0.0LeuXaa: 0.0 ± 0.0
Met
1.514MetAla: 1.514 ± 0.821
0.0MetCys: 0.0 ± 0.0
1.514MetAsp: 1.514 ± 0.173
1.211MetGlu: 1.211 ± 0.322
1.211MetPhe: 1.211 ± 0.322
1.211MetGly: 1.211 ± 0.854
1.211MetHis: 1.211 ± 0.355
1.211MetIle: 1.211 ± 0.657
1.211MetLys: 1.211 ± 0.4
1.817MetLeu: 1.817 ± 0.694
0.606MetMet: 0.606 ± 1.047
0.606MetAsn: 0.606 ± 0.329
0.606MetPro: 0.606 ± 1.047
1.817MetGln: 1.817 ± 0.694
2.12MetArg: 2.12 ± 0.308
0.909MetSer: 0.909 ± 0.284
1.817MetThr: 1.817 ± 0.694
2.12MetVal: 2.12 ± 1.425
0.303MetTrp: 0.303 ± 0.164
0.606MetTyr: 0.606 ± 0.299
0.0MetXaa: 0.0 ± 0.0
Asn
2.423AsnAla: 2.423 ± 1.707
0.0AsnCys: 0.0 ± 0.0
0.606AsnAsp: 0.606 ± 0.329
1.817AsnGlu: 1.817 ± 0.694
1.514AsnPhe: 1.514 ± 0.821
1.514AsnGly: 1.514 ± 0.56
0.303AsnHis: 0.303 ± 0.164
3.331AsnIle: 3.331 ± 0.881
1.817AsnLys: 1.817 ± 0.102
1.817AsnLeu: 1.817 ± 0.102
1.211AsnMet: 1.211 ± 0.854
0.606AsnAsn: 0.606 ± 0.329
1.817AsnPro: 1.817 ± 0.76
1.514AsnGln: 1.514 ± 0.56
1.514AsnArg: 1.514 ± 0.475
1.514AsnSer: 1.514 ± 0.173
3.937AsnThr: 3.937 ± 0.547
2.726AsnVal: 2.726 ± 0.478
0.303AsnTrp: 0.303 ± 0.523
1.211AsnTyr: 1.211 ± 0.4
0.0AsnXaa: 0.0 ± 0.0
Pro
3.937ProAla: 3.937 ± 1.911
0.606ProCys: 0.606 ± 0.329
3.331ProAsp: 3.331 ± 0.232
3.937ProGlu: 3.937 ± 0.659
3.634ProPhe: 3.634 ± 0.477
3.028ProGly: 3.028 ± 0.934
0.909ProHis: 0.909 ± 0.493
5.148ProIle: 5.148 ± 0.901
1.514ProLys: 1.514 ± 0.606
4.24ProLeu: 4.24 ± 1.295
1.211ProMet: 1.211 ± 0.959
1.211ProAsn: 1.211 ± 0.599
3.634ProPro: 3.634 ± 1.355
2.12ProGln: 2.12 ± 1.425
4.24ProArg: 4.24 ± 0.616
3.937ProSer: 3.937 ± 0.241
2.423ProThr: 2.423 ± 0.92
3.028ProVal: 3.028 ± 0.302
0.909ProTrp: 0.909 ± 0.38
3.331ProTyr: 3.331 ± 0.444
0.0ProXaa: 0.0 ± 0.0
Gln
3.331GlnAla: 3.331 ± 1.543
1.514GlnCys: 1.514 ± 0.475
0.909GlnAsp: 0.909 ± 0.493
3.028GlnGlu: 3.028 ± 0.346
1.211GlnPhe: 1.211 ± 0.322
2.12GlnGly: 2.12 ± 0.308
2.12GlnHis: 2.12 ± 0.763
3.331GlnIle: 3.331 ± 1.056
2.12GlnLys: 2.12 ± 1.217
4.24GlnLeu: 4.24 ± 1.34
0.606GlnMet: 0.606 ± 0.557
1.514GlnAsn: 1.514 ± 0.791
1.817GlnPro: 1.817 ± 0.967
3.028GlnGln: 3.028 ± 2.245
1.514GlnArg: 1.514 ± 0.791
1.211GlnSer: 1.211 ± 1.062
1.211GlnThr: 1.211 ± 0.355
1.817GlnVal: 1.817 ± 0.452
0.909GlnTrp: 0.909 ± 0.284
3.028GlnTyr: 3.028 ± 0.934
0.0GlnXaa: 0.0 ± 0.0
Arg
5.451ArgAla: 5.451 ± 0.818
0.909ArgCys: 0.909 ± 0.676
5.754ArgAsp: 5.754 ± 1.206
4.24ArgGlu: 4.24 ± 1.652
2.726ArgPhe: 2.726 ± 0.869
2.12ArgGly: 2.12 ± 0.308
2.423ArgHis: 2.423 ± 0.644
5.148ArgIle: 5.148 ± 0.889
1.514ArgLys: 1.514 ± 0.821
8.177ArgLeu: 8.177 ± 1.369
1.211ArgMet: 1.211 ± 0.322
2.726ArgAsn: 2.726 ± 1.011
2.423ArgPro: 2.423 ± 0.92
2.12ArgGln: 2.12 ± 0.622
6.663ArgArg: 6.663 ± 1.148
3.331ArgSer: 3.331 ± 1.336
4.543ArgThr: 4.543 ± 0.52
3.937ArgVal: 3.937 ± 0.75
0.909ArgTrp: 0.909 ± 0.38
2.726ArgTyr: 2.726 ± 1.078
0.0ArgXaa: 0.0 ± 0.0
Ser
4.543SerAla: 4.543 ± 2.92
0.909SerCys: 0.909 ± 0.284
1.817SerAsp: 1.817 ± 0.986
4.24SerGlu: 4.24 ± 0.917
1.514SerPhe: 1.514 ± 0.475
3.634SerGly: 3.634 ± 0.4
1.514SerHis: 1.514 ± 0.97
3.634SerIle: 3.634 ± 1.065
2.726SerLys: 2.726 ± 1.478
6.057SerLeu: 6.057 ± 1.251
0.303SerMet: 0.303 ± 0.293
2.12SerAsn: 2.12 ± 0.765
3.028SerPro: 3.028 ± 0.971
1.817SerGln: 1.817 ± 0.76
3.028SerArg: 3.028 ± 1.237
4.24SerSer: 4.24 ± 1.548
2.423SerThr: 2.423 ± 0.199
3.028SerVal: 3.028 ± 0.502
0.909SerTrp: 0.909 ± 0.493
1.817SerTyr: 1.817 ± 0.595
0.0SerXaa: 0.0 ± 0.0
Thr
7.268ThrAla: 7.268 ± 2.243
1.514ThrCys: 1.514 ± 0.56
2.726ThrAsp: 2.726 ± 0.869
3.028ThrGlu: 3.028 ± 0.302
1.817ThrPhe: 1.817 ± 0.967
2.726ThrGly: 2.726 ± 0.196
3.634ThrHis: 3.634 ± 1.065
4.543ThrIle: 4.543 ± 1.085
1.211ThrLys: 1.211 ± 0.355
8.177ThrLeu: 8.177 ± 1.191
1.514ThrMet: 1.514 ± 0.48
0.909ThrAsn: 0.909 ± 0.481
3.331ThrPro: 3.331 ± 1.36
3.331ThrGln: 3.331 ± 0.881
4.846ThrArg: 4.846 ± 0.698
3.937ThrSer: 3.937 ± 1.379
5.754ThrThr: 5.754 ± 1.641
3.331ThrVal: 3.331 ± 1.745
1.211ThrTrp: 1.211 ± 0.4
2.423ThrTyr: 2.423 ± 0.71
0.0ThrXaa: 0.0 ± 0.0
Val
7.268ValAla: 7.268 ± 1.207
0.909ValCys: 0.909 ± 0.284
2.423ValAsp: 2.423 ± 0.695
3.331ValGlu: 3.331 ± 0.232
3.028ValPhe: 3.028 ± 0.687
4.24ValGly: 4.24 ± 2.564
2.423ValHis: 2.423 ± 1.211
3.634ValIle: 3.634 ± 0.598
1.817ValLys: 1.817 ± 0.615
6.36ValLeu: 6.36 ± 0.407
0.606ValMet: 0.606 ± 0.299
2.726ValAsn: 2.726 ± 0.196
3.937ValPro: 3.937 ± 0.865
3.634ValGln: 3.634 ± 2.235
5.148ValArg: 5.148 ± 0.314
3.634ValSer: 3.634 ± 0.598
3.937ValThr: 3.937 ± 2.31
5.451ValVal: 5.451 ± 1.695
0.606ValTrp: 0.606 ± 0.642
3.331ValTyr: 3.331 ± 1.123
0.0ValXaa: 0.0 ± 0.0
Trp
1.817TrpAla: 1.817 ± 1.882
0.303TrpCys: 0.303 ± 0.164
0.303TrpAsp: 0.303 ± 0.164
0.606TrpGlu: 0.606 ± 0.299
0.303TrpPhe: 0.303 ± 0.164
0.909TrpGly: 0.909 ± 0.284
0.909TrpHis: 0.909 ± 0.481
0.606TrpIle: 0.606 ± 0.329
0.0TrpLys: 0.0 ± 0.0
0.606TrpLeu: 0.606 ± 0.427
0.303TrpMet: 0.303 ± 0.523
0.606TrpAsn: 0.606 ± 0.329
0.909TrpPro: 0.909 ± 0.493
0.606TrpGln: 0.606 ± 0.427
0.606TrpArg: 0.606 ± 0.329
0.909TrpSer: 0.909 ± 0.284
1.211TrpThr: 1.211 ± 0.355
1.514TrpVal: 1.514 ± 0.475
0.0TrpTrp: 0.0 ± 0.0
0.303TrpTyr: 0.303 ± 0.164
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.148TyrAla: 5.148 ± 1.701
0.909TyrCys: 0.909 ± 0.38
3.331TyrAsp: 3.331 ± 0.873
0.909TyrGlu: 0.909 ± 0.38
0.606TyrPhe: 0.606 ± 0.427
1.817TyrGly: 1.817 ± 0.452
1.514TyrHis: 1.514 ± 0.821
0.606TyrIle: 0.606 ± 0.329
2.423TyrLys: 2.423 ± 0.199
5.148TyrLeu: 5.148 ± 2.372
2.726TyrMet: 2.726 ± 0.196
1.514TyrAsn: 1.514 ± 0.475
3.331TyrPro: 3.331 ± 0.881
1.211TyrGln: 1.211 ± 0.355
2.12TyrArg: 2.12 ± 0.212
3.028TyrSer: 3.028 ± 0.498
3.937TyrThr: 3.937 ± 0.659
2.423TyrVal: 2.423 ± 0.644
0.909TyrTrp: 0.909 ± 0.284
1.514TyrTyr: 1.514 ± 0.821
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3303 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski