Amino acid dipepetide frequency for White clover cryptic virus 1 (isolate Boccardo/2004) (WCCV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.797AlaAla: 11.797 ± 5.742
0.0AlaCys: 0.0 ± 0.0
1.815AlaAsp: 1.815 ± 0.158
3.63AlaGlu: 3.63 ± 0.316
5.445AlaPhe: 5.445 ± 1.821
3.63AlaGly: 3.63 ± 0.316
2.722AlaHis: 2.722 ± 0.91
4.537AlaIle: 4.537 ± 1.068
0.0AlaLys: 0.0 ± 0.0
1.815AlaLeu: 1.815 ± 0.158
1.815AlaMet: 1.815 ± 1.505
6.352AlaAsn: 6.352 ± 2.574
8.167AlaPro: 8.167 ± 2.731
8.167AlaGln: 8.167 ± 2.731
6.352AlaArg: 6.352 ± 2.574
3.63AlaSer: 3.63 ± 0.316
6.352AlaThr: 6.352 ± 1.226
3.63AlaVal: 3.63 ± 1.663
0.907AlaTrp: 0.907 ± 0.595
4.537AlaTyr: 4.537 ± 1.068
0.0AlaXaa: 0.0 ± 0.0
Cys
0.907CysAla: 0.907 ± 0.595
0.0CysCys: 0.0 ± 0.0
1.815CysAsp: 1.815 ± 1.505
0.907CysGlu: 0.907 ± 0.595
0.0CysPhe: 0.0 ± 0.0
1.815CysGly: 1.815 ± 0.158
0.907CysHis: 0.907 ± 0.753
0.907CysIle: 0.907 ± 0.595
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.815CysMet: 1.815 ± 0.158
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.907CysArg: 0.907 ± 0.595
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.722AspAla: 2.722 ± 2.258
0.0AspCys: 0.0 ± 0.0
0.907AspAsp: 0.907 ± 0.595
4.537AspGlu: 4.537 ± 1.627
2.722AspPhe: 2.722 ± 1.785
1.815AspGly: 1.815 ± 0.158
2.722AspHis: 2.722 ± 0.437
0.907AspIle: 0.907 ± 0.753
2.722AspLys: 2.722 ± 1.785
4.537AspLeu: 4.537 ± 1.627
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
2.722AspPro: 2.722 ± 1.785
2.722AspGln: 2.722 ± 0.91
2.722AspArg: 2.722 ± 0.437
5.445AspSer: 5.445 ± 2.222
2.722AspThr: 2.722 ± 0.91
4.537AspVal: 4.537 ± 0.279
2.722AspTrp: 2.722 ± 0.91
0.907AspTyr: 0.907 ± 0.595
0.0AspXaa: 0.0 ± 0.0
Glu
1.815GluAla: 1.815 ± 1.19
1.815GluCys: 1.815 ± 0.158
4.537GluAsp: 4.537 ± 1.627
1.815GluGlu: 1.815 ± 0.158
1.815GluPhe: 1.815 ± 0.158
1.815GluGly: 1.815 ± 0.158
2.722GluHis: 2.722 ± 1.785
5.445GluIle: 5.445 ± 2.222
0.0GluLys: 0.0 ± 0.0
3.63GluLeu: 3.63 ± 1.663
1.815GluMet: 1.815 ± 0.516
1.815GluAsn: 1.815 ± 1.19
0.907GluPro: 0.907 ± 0.595
3.63GluGln: 3.63 ± 1.663
1.815GluArg: 1.815 ± 1.19
0.907GluSer: 0.907 ± 0.595
2.722GluThr: 2.722 ± 1.785
2.722GluVal: 2.722 ± 0.437
0.907GluTrp: 0.907 ± 0.753
5.445GluTyr: 5.445 ± 2.222
0.0GluXaa: 0.0 ± 0.0
Phe
6.352PheAla: 6.352 ± 2.574
0.907PheCys: 0.907 ± 0.595
5.445PheAsp: 5.445 ± 0.874
3.63PheGlu: 3.63 ± 1.032
3.63PhePhe: 3.63 ± 1.032
2.722PheGly: 2.722 ± 1.785
0.907PheHis: 0.907 ± 0.753
4.537PheIle: 4.537 ± 1.627
0.0PheLys: 0.0 ± 0.0
7.26PheLeu: 7.26 ± 2.064
1.815PheMet: 1.815 ± 0.158
4.537PheAsn: 4.537 ± 0.279
3.63PhePro: 3.63 ± 1.032
1.815PheGln: 1.815 ± 0.158
4.537PheArg: 4.537 ± 0.279
2.722PheSer: 2.722 ± 1.785
4.537PheThr: 4.537 ± 2.416
0.0PheVal: 0.0 ± 0.0
0.907PheTrp: 0.907 ± 0.753
1.815PheTyr: 1.815 ± 1.19
0.0PheXaa: 0.0 ± 0.0
Gly
6.352GlyAla: 6.352 ± 2.574
0.907GlyCys: 0.907 ± 0.595
3.63GlyAsp: 3.63 ± 1.032
2.722GlyGlu: 2.722 ± 0.437
4.537GlyPhe: 4.537 ± 0.279
0.907GlyGly: 0.907 ± 0.595
0.0GlyHis: 0.0 ± 0.0
1.815GlyIle: 1.815 ± 0.158
0.0GlyLys: 0.0 ± 0.0
5.445GlyLeu: 5.445 ± 3.57
0.0GlyMet: 0.0 ± 0.0
1.815GlyAsn: 1.815 ± 1.505
6.352GlyPro: 6.352 ± 5.269
0.0GlyGln: 0.0 ± 0.0
1.815GlyArg: 1.815 ± 0.158
2.722GlySer: 2.722 ± 0.91
0.907GlyThr: 0.907 ± 0.753
0.907GlyVal: 0.907 ± 0.753
0.907GlyTrp: 0.907 ± 0.595
5.445GlyTyr: 5.445 ± 2.222
0.0GlyXaa: 0.0 ± 0.0
His
2.722HisAla: 2.722 ± 0.91
0.907HisCys: 0.907 ± 0.595
1.815HisAsp: 1.815 ± 0.158
3.63HisGlu: 3.63 ± 1.032
2.722HisPhe: 2.722 ± 1.785
1.815HisGly: 1.815 ± 0.158
0.907HisHis: 0.907 ± 0.595
4.537HisIle: 4.537 ± 1.627
1.815HisLys: 1.815 ± 0.158
0.907HisLeu: 0.907 ± 0.753
0.0HisMet: 0.0 ± 0.0
3.63HisAsn: 3.63 ± 1.032
1.815HisPro: 1.815 ± 1.19
1.815HisGln: 1.815 ± 1.505
0.907HisArg: 0.907 ± 0.595
0.0HisSer: 0.0 ± 0.0
6.352HisThr: 6.352 ± 0.122
0.907HisVal: 0.907 ± 0.595
0.907HisTrp: 0.907 ± 0.595
0.907HisTyr: 0.907 ± 0.595
0.0HisXaa: 0.0 ± 0.0
Ile
2.722IleAla: 2.722 ± 0.91
0.0IleCys: 0.0 ± 0.0
3.63IleAsp: 3.63 ± 1.032
2.722IleGlu: 2.722 ± 0.91
2.722IlePhe: 2.722 ± 0.437
3.63IleGly: 3.63 ± 0.316
0.907IleHis: 0.907 ± 0.753
4.537IleIle: 4.537 ± 1.627
2.722IleLys: 2.722 ± 1.785
8.167IleLeu: 8.167 ± 1.312
0.907IleMet: 0.907 ± 0.753
2.722IleAsn: 2.722 ± 0.437
6.352IlePro: 6.352 ± 1.226
0.907IleGln: 0.907 ± 0.595
1.815IleArg: 1.815 ± 1.19
2.722IleSer: 2.722 ± 2.258
5.445IleThr: 5.445 ± 3.57
3.63IleVal: 3.63 ± 1.032
0.907IleTrp: 0.907 ± 0.595
0.907IleTyr: 0.907 ± 0.753
0.0IleXaa: 0.0 ± 0.0
Lys
1.815LysAla: 1.815 ± 1.19
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.815LysGlu: 1.815 ± 1.19
0.907LysPhe: 0.907 ± 0.595
0.0LysGly: 0.0 ± 0.0
1.815LysHis: 1.815 ± 1.19
0.0LysIle: 0.0 ± 0.0
1.815LysLys: 1.815 ± 1.19
0.0LysLeu: 0.0 ± 0.0
0.907LysMet: 0.907 ± 0.595
0.907LysAsn: 0.907 ± 0.595
0.907LysPro: 0.907 ± 0.595
0.0LysGln: 0.0 ± 0.0
0.907LysArg: 0.907 ± 0.595
4.537LysSer: 4.537 ± 1.627
3.63LysThr: 3.63 ± 1.032
1.815LysVal: 1.815 ± 0.158
1.815LysTrp: 1.815 ± 0.158
1.815LysTyr: 1.815 ± 0.158
0.0LysXaa: 0.0 ± 0.0
Leu
7.26LeuAla: 7.26 ± 0.631
1.815LeuCys: 1.815 ± 1.505
6.352LeuAsp: 6.352 ± 1.469
8.167LeuGlu: 8.167 ± 2.659
5.445LeuPhe: 5.445 ± 0.874
3.63LeuGly: 3.63 ± 1.663
2.722LeuHis: 2.722 ± 1.785
4.537LeuIle: 4.537 ± 1.627
3.63LeuLys: 3.63 ± 1.663
7.26LeuLeu: 7.26 ± 0.631
1.815LeuMet: 1.815 ± 1.505
3.63LeuAsn: 3.63 ± 0.316
6.352LeuPro: 6.352 ± 0.122
2.722LeuGln: 2.722 ± 2.258
5.445LeuArg: 5.445 ± 0.874
3.63LeuSer: 3.63 ± 1.032
6.352LeuThr: 6.352 ± 4.165
0.907LeuVal: 0.907 ± 0.753
5.445LeuTrp: 5.445 ± 0.874
4.537LeuTyr: 4.537 ± 1.068
0.0LeuXaa: 0.0 ± 0.0
Met
2.722MetAla: 2.722 ± 0.437
0.0MetCys: 0.0 ± 0.0
1.815MetAsp: 1.815 ± 1.19
0.0MetGlu: 0.0 ± 0.0
0.907MetPhe: 0.907 ± 0.595
0.0MetGly: 0.0 ± 0.0
2.722MetHis: 2.722 ± 0.91
2.722MetIle: 2.722 ± 0.91
0.907MetLys: 0.907 ± 0.753
4.537MetLeu: 4.537 ± 1.627
0.0MetMet: 0.0 ± 0.0
0.907MetAsn: 0.907 ± 0.753
3.63MetPro: 3.63 ± 0.316
0.0MetGln: 0.0 ± 0.0
0.907MetArg: 0.907 ± 0.595
0.0MetSer: 0.0 ± 0.0
0.907MetThr: 0.907 ± 0.753
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.815MetTyr: 1.815 ± 0.158
0.0MetXaa: 0.0 ± 0.0
Asn
4.537AsnAla: 4.537 ± 0.279
0.0AsnCys: 0.0 ± 0.0
1.815AsnAsp: 1.815 ± 1.19
1.815AsnGlu: 1.815 ± 0.158
1.815AsnPhe: 1.815 ± 0.158
6.352AsnGly: 6.352 ± 2.574
5.445AsnHis: 5.445 ± 0.874
2.722AsnIle: 2.722 ± 0.437
0.907AsnLys: 0.907 ± 0.595
3.63AsnLeu: 3.63 ± 1.032
0.907AsnMet: 0.907 ± 0.753
1.815AsnAsn: 1.815 ± 1.505
3.63AsnPro: 3.63 ± 1.663
1.815AsnGln: 1.815 ± 1.505
4.537AsnArg: 4.537 ± 1.627
1.815AsnSer: 1.815 ± 1.19
1.815AsnThr: 1.815 ± 1.505
5.445AsnVal: 5.445 ± 1.821
0.907AsnTrp: 0.907 ± 0.753
4.537AsnTyr: 4.537 ± 1.068
0.0AsnXaa: 0.0 ± 0.0
Pro
10.889ProAla: 10.889 ± 7.685
0.907ProCys: 0.907 ± 0.595
2.722ProAsp: 2.722 ± 0.437
2.722ProGlu: 2.722 ± 0.437
5.445ProPhe: 5.445 ± 1.821
4.537ProGly: 4.537 ± 0.279
2.722ProHis: 2.722 ± 0.91
3.63ProIle: 3.63 ± 0.316
0.907ProLys: 0.907 ± 0.595
7.26ProLeu: 7.26 ± 1.979
2.722ProMet: 2.722 ± 0.437
3.63ProAsn: 3.63 ± 1.032
9.074ProPro: 9.074 ± 2.136
2.722ProGln: 2.722 ± 0.91
2.722ProArg: 2.722 ± 0.437
4.537ProSer: 4.537 ± 2.416
4.537ProThr: 4.537 ± 2.975
3.63ProVal: 3.63 ± 1.663
0.907ProTrp: 0.907 ± 0.595
1.815ProTyr: 1.815 ± 1.19
0.0ProXaa: 0.0 ± 0.0
Gln
3.63GlnAla: 3.63 ± 1.663
0.907GlnCys: 0.907 ± 0.753
3.63GlnAsp: 3.63 ± 1.663
0.907GlnGlu: 0.907 ± 0.595
1.815GlnPhe: 1.815 ± 0.158
2.722GlnGly: 2.722 ± 0.91
0.907GlnHis: 0.907 ± 0.595
1.815GlnIle: 1.815 ± 1.505
0.0GlnLys: 0.0 ± 0.0
7.26GlnLeu: 7.26 ± 4.674
0.0GlnMet: 0.0 ± 0.0
2.722GlnAsn: 2.722 ± 0.437
0.907GlnPro: 0.907 ± 0.753
1.815GlnGln: 1.815 ± 1.505
2.722GlnArg: 2.722 ± 0.437
1.815GlnSer: 1.815 ± 1.505
1.815GlnThr: 1.815 ± 0.158
0.907GlnVal: 0.907 ± 0.753
0.907GlnTrp: 0.907 ± 0.595
1.815GlnTyr: 1.815 ± 1.505
0.0GlnXaa: 0.0 ± 0.0
Arg
5.445ArgAla: 5.445 ± 1.821
0.0ArgCys: 0.0 ± 0.0
3.63ArgAsp: 3.63 ± 1.032
0.907ArgGlu: 0.907 ± 0.753
5.445ArgPhe: 5.445 ± 1.821
0.907ArgGly: 0.907 ± 0.595
1.815ArgHis: 1.815 ± 1.19
2.722ArgIle: 2.722 ± 0.437
0.907ArgLys: 0.907 ± 0.595
6.352ArgLeu: 6.352 ± 1.469
1.815ArgMet: 1.815 ± 1.19
2.722ArgAsn: 2.722 ± 0.437
3.63ArgPro: 3.63 ± 2.38
0.907ArgGln: 0.907 ± 0.753
8.167ArgArg: 8.167 ± 1.312
5.445ArgSer: 5.445 ± 0.473
4.537ArgThr: 4.537 ± 1.627
1.815ArgVal: 1.815 ± 1.19
0.907ArgTrp: 0.907 ± 0.595
2.722ArgTyr: 2.722 ± 0.91
0.0ArgXaa: 0.0 ± 0.0
Ser
3.63SerAla: 3.63 ± 1.663
0.907SerCys: 0.907 ± 0.595
0.0SerAsp: 0.0 ± 0.0
1.815SerGlu: 1.815 ± 1.19
2.722SerPhe: 2.722 ± 0.437
3.63SerGly: 3.63 ± 1.032
0.907SerHis: 0.907 ± 0.595
4.537SerIle: 4.537 ± 0.279
0.907SerLys: 0.907 ± 0.595
5.445SerLeu: 5.445 ± 1.821
1.815SerMet: 1.815 ± 0.158
1.815SerAsn: 1.815 ± 1.505
3.63SerPro: 3.63 ± 0.316
3.63SerGln: 3.63 ± 0.316
2.722SerArg: 2.722 ± 0.91
0.0SerSer: 0.0 ± 0.0
2.722SerThr: 2.722 ± 0.437
2.722SerVal: 2.722 ± 2.258
2.722SerTrp: 2.722 ± 0.437
1.815SerTyr: 1.815 ± 1.19
0.0SerXaa: 0.0 ± 0.0
Thr
2.722ThrAla: 2.722 ± 0.437
0.0ThrCys: 0.0 ± 0.0
3.63ThrAsp: 3.63 ± 0.316
2.722ThrGlu: 2.722 ± 0.91
5.445ThrPhe: 5.445 ± 2.222
2.722ThrGly: 2.722 ± 0.437
4.537ThrHis: 4.537 ± 1.627
1.815ThrIle: 1.815 ± 1.19
3.63ThrLys: 3.63 ± 2.38
8.167ThrLeu: 8.167 ± 1.312
4.537ThrMet: 4.537 ± 2.975
5.445ThrAsn: 5.445 ± 1.821
5.445ThrPro: 5.445 ± 0.473
3.63ThrGln: 3.63 ± 1.663
2.722ThrArg: 2.722 ± 0.91
0.0ThrSer: 0.0 ± 0.0
3.63ThrThr: 3.63 ± 1.663
1.815ThrVal: 1.815 ± 1.19
0.907ThrTrp: 0.907 ± 0.595
0.907ThrTyr: 0.907 ± 0.595
0.0ThrXaa: 0.0 ± 0.0
Val
2.722ValAla: 2.722 ± 0.437
0.907ValCys: 0.907 ± 0.753
0.907ValAsp: 0.907 ± 0.595
0.907ValGlu: 0.907 ± 0.595
0.0ValPhe: 0.0 ± 0.0
0.907ValGly: 0.907 ± 0.753
0.0ValHis: 0.0 ± 0.0
1.815ValIle: 1.815 ± 1.505
3.63ValLys: 3.63 ± 2.38
4.537ValLeu: 4.537 ± 0.279
0.907ValMet: 0.907 ± 0.753
6.352ValAsn: 6.352 ± 1.226
7.26ValPro: 7.26 ± 3.326
1.815ValGln: 1.815 ± 0.158
3.63ValArg: 3.63 ± 0.316
2.722ValSer: 2.722 ± 2.258
0.0ValThr: 0.0 ± 0.0
0.907ValVal: 0.907 ± 0.595
0.0ValTrp: 0.0 ± 0.0
1.815ValTyr: 1.815 ± 0.158
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.907TrpGlu: 0.907 ± 0.595
2.722TrpPhe: 2.722 ± 0.437
1.815TrpGly: 1.815 ± 1.19
0.907TrpHis: 0.907 ± 0.595
2.722TrpIle: 2.722 ± 0.437
0.0TrpLys: 0.0 ± 0.0
2.722TrpLeu: 2.722 ± 0.91
0.0TrpMet: 0.0 ± 0.0
3.63TrpAsn: 3.63 ± 1.663
0.907TrpPro: 0.907 ± 0.595
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.815TrpSer: 1.815 ± 1.19
2.722TrpThr: 2.722 ± 0.437
0.907TrpVal: 0.907 ± 0.595
0.0TrpTrp: 0.0 ± 0.0
2.722TrpTyr: 2.722 ± 0.91
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.537TyrAla: 4.537 ± 2.416
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.722TyrGlu: 2.722 ± 1.785
5.445TyrPhe: 5.445 ± 2.222
1.815TyrGly: 1.815 ± 1.505
2.722TyrHis: 2.722 ± 0.437
1.815TyrIle: 1.815 ± 0.158
0.907TyrLys: 0.907 ± 0.595
2.722TyrLeu: 2.722 ± 1.785
0.0TyrMet: 0.0 ± 0.0
1.815TyrAsn: 1.815 ± 1.19
2.722TyrPro: 2.722 ± 0.91
0.907TyrGln: 0.907 ± 0.595
5.445TyrArg: 5.445 ± 2.222
3.63TyrSer: 3.63 ± 1.663
2.722TyrThr: 2.722 ± 0.437
4.537TyrVal: 4.537 ± 2.416
1.815TyrTrp: 1.815 ± 0.158
1.815TyrTyr: 1.815 ± 0.158
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1103 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski