Amino acid dipepetide frequency for Allochromatium warmingii (Chromatium warmingii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.235AlaAla: 15.235 ± 0.192	1.277AlaCys: 1.277 ± 0.049	6.614AlaAsp: 6.614 ± 0.086	7.86AlaGlu: 7.86 ± 0.089	3.416AlaPhe: 3.416 ± 0.072	8.088AlaGly: 8.088 ± 0.111	2.935AlaHis: 2.935 ± 0.073	5.807AlaIle: 5.807 ± 0.087	2.862AlaLys: 2.862 ± 0.073	14.307AlaLeu: 14.307 ± 0.156	2.519AlaMet: 2.519 ± 0.056	3.003AlaAsn: 3.003 ± 0.082	5.663AlaPro: 5.663 ± 0.123	5.334AlaGln: 5.334 ± 0.101	8.18AlaArg: 8.18 ± 0.121	5.296AlaSer: 5.296 ± 0.09	5.957AlaThr: 5.957 ± 0.093	7.942AlaVal: 7.942 ± 0.112	1.551AlaTrp: 1.551 ± 0.048	2.426AlaTyr: 2.426 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.198CysAla: 1.198 ± 0.043	0.16CysCys: 0.16 ± 0.013	0.621CysAsp: 0.621 ± 0.027	0.628CysGlu: 0.628 ± 0.03	0.376CysPhe: 0.376 ± 0.019	1.004CysGly: 1.004 ± 0.037	0.321CysHis: 0.321 ± 0.025	0.5CysIle: 0.5 ± 0.029	0.251CysLys: 0.251 ± 0.019	1.044CysLeu: 1.044 ± 0.038	0.172CysMet: 0.172 ± 0.015	0.3CysAsn: 0.3 ± 0.017	0.627CysPro: 0.627 ± 0.032	0.46CysGln: 0.46 ± 0.02	0.741CysArg: 0.741 ± 0.028	0.528CysSer: 0.528 ± 0.024	0.499CysThr: 0.499 ± 0.026	0.784CysVal: 0.784 ± 0.037	0.137CysTrp: 0.137 ± 0.012	0.276CysTyr: 0.276 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	6.878AspAla: 6.878 ± 0.109	0.662AspCys: 0.662 ± 0.032	3.019AspAsp: 3.019 ± 0.072	3.241AspGlu: 3.241 ± 0.058	2.215AspPhe: 2.215 ± 0.058	4.448AspGly: 4.448 ± 0.084	1.188AspHis: 1.188 ± 0.035	2.847AspIle: 2.847 ± 0.065	1.341AspLys: 1.341 ± 0.049	6.623AspLeu: 6.623 ± 0.099	1.085AspMet: 1.085 ± 0.037	1.343AspAsn: 1.343 ± 0.048	3.515AspPro: 3.515 ± 0.061	2.25AspGln: 2.25 ± 0.051	3.713AspArg: 3.713 ± 0.061	2.712AspSer: 2.712 ± 0.06	2.761AspThr: 2.761 ± 0.063	3.521AspVal: 3.521 ± 0.068	1.24AspTrp: 1.24 ± 0.038	1.854AspTyr: 1.854 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	6.685GluAla: 6.685 ± 0.099	0.53GluCys: 0.53 ± 0.024	2.403GluAsp: 2.403 ± 0.056	2.58GluGlu: 2.58 ± 0.066	1.836GluPhe: 1.836 ± 0.047	3.025GluGly: 3.025 ± 0.078	1.818GluHis: 1.818 ± 0.046	3.706GluIle: 3.706 ± 0.074	1.649GluLys: 1.649 ± 0.067	7.486GluLeu: 7.486 ± 0.117	1.198GluMet: 1.198 ± 0.041	1.412GluAsn: 1.412 ± 0.046	2.929GluPro: 2.929 ± 0.077	3.962GluGln: 3.962 ± 0.079	6.569GluArg: 6.569 ± 0.113	3.055GluSer: 3.055 ± 0.059	3.652GluThr: 3.652 ± 0.065	3.709GluVal: 3.709 ± 0.074	0.707GluTrp: 0.707 ± 0.028	1.265GluTyr: 1.265 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.833PheAla: 3.833 ± 0.071	0.427PheCys: 0.427 ± 0.025	2.445PheAsp: 2.445 ± 0.061	2.306PheGlu: 2.306 ± 0.052	1.328PhePhe: 1.328 ± 0.044	2.997PheGly: 2.997 ± 0.064	0.717PheHis: 0.717 ± 0.026	1.784PheIle: 1.784 ± 0.047	1.116PheLys: 1.116 ± 0.043	3.131PheLeu: 3.131 ± 0.067	0.714PheMet: 0.714 ± 0.036	1.217PheAsn: 1.217 ± 0.044	1.334PhePro: 1.334 ± 0.042	1.286PheGln: 1.286 ± 0.038	1.862PheArg: 1.862 ± 0.043	1.971PheSer: 1.971 ± 0.051	1.822PheThr: 1.822 ± 0.052	2.312PheVal: 2.312 ± 0.057	0.497PheTrp: 0.497 ± 0.027	0.955PheTyr: 0.955 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	7.14GlyAla: 7.14 ± 0.104	1.014GlyCys: 1.014 ± 0.037	3.548GlyAsp: 3.548 ± 0.077	4.39GlyGlu: 4.39 ± 0.075	2.976GlyPhe: 2.976 ± 0.065	5.151GlyGly: 5.151 ± 0.096	1.759GlyHis: 1.759 ± 0.052	3.995GlyIle: 3.995 ± 0.077	2.242GlyLys: 2.242 ± 0.063	8.568GlyLeu: 8.568 ± 0.135	1.7GlyMet: 1.7 ± 0.047	1.803GlyAsn: 1.803 ± 0.066	2.274GlyPro: 2.274 ± 0.063	3.484GlyGln: 3.484 ± 0.073	5.41GlyArg: 5.41 ± 0.089	3.497GlySer: 3.497 ± 0.07	3.753GlyThr: 3.753 ± 0.09	5.3GlyVal: 5.3 ± 0.094	1.216GlyTrp: 1.216 ± 0.041	2.233GlyTyr: 2.233 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.773HisAla: 2.773 ± 0.062	0.364HisCys: 0.364 ± 0.02	1.286HisAsp: 1.286 ± 0.047	1.268HisGlu: 1.268 ± 0.038	0.889HisPhe: 0.889 ± 0.03	1.986HisGly: 1.986 ± 0.055	0.757HisHis: 0.757 ± 0.033	1.195HisIle: 1.195 ± 0.037	0.515HisLys: 0.515 ± 0.026	2.891HisLeu: 2.891 ± 0.064	0.412HisMet: 0.412 ± 0.022	0.623HisAsn: 0.623 ± 0.026	1.718HisPro: 1.718 ± 0.047	1.137HisGln: 1.137 ± 0.038	1.745HisArg: 1.745 ± 0.052	1.245HisSer: 1.245 ± 0.04	1.241HisThr: 1.241 ± 0.038	1.407HisVal: 1.407 ± 0.045	0.489HisTrp: 0.489 ± 0.024	0.743HisTyr: 0.743 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.542IleAla: 6.542 ± 0.096	0.51IleCys: 0.51 ± 0.022	3.602IleAsp: 3.602 ± 0.073	4.123IleGlu: 4.123 ± 0.072	1.561IlePhe: 1.561 ± 0.049	4.467IleGly: 4.467 ± 0.081	1.216IleHis: 1.216 ± 0.038	2.342IleIle: 2.342 ± 0.064	1.749IleLys: 1.749 ± 0.05	5.026IleLeu: 5.026 ± 0.084	0.819IleMet: 0.819 ± 0.034	1.78IleAsn: 1.78 ± 0.05	2.576IlePro: 2.576 ± 0.054	2.211IleGln: 2.211 ± 0.049	3.585IleArg: 3.585 ± 0.069	2.575IleSer: 2.575 ± 0.063	2.87IleThr: 2.87 ± 0.071	3.412IleVal: 3.412 ± 0.075	0.609IleTrp: 0.609 ± 0.034	1.137IleTyr: 1.137 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	2.78LysAla: 2.78 ± 0.069	0.228LysCys: 0.228 ± 0.019	1.422LysAsp: 1.422 ± 0.049	1.343LysGlu: 1.343 ± 0.06	0.798LysPhe: 0.798 ± 0.038	1.826LysGly: 1.826 ± 0.059	0.719LysHis: 0.719 ± 0.031	1.519LysIle: 1.519 ± 0.049	1.172LysLys: 1.172 ± 0.057	2.989LysLeu: 2.989 ± 0.074	0.496LysMet: 0.496 ± 0.03	0.914LysAsn: 0.914 ± 0.047	1.741LysPro: 1.741 ± 0.055	1.335LysGln: 1.335 ± 0.044	2.334LysArg: 2.334 ± 0.056	1.589LysSer: 1.589 ± 0.046	1.785LysThr: 1.785 ± 0.057	1.568LysVal: 1.568 ± 0.053	0.287LysTrp: 0.287 ± 0.017	0.637LysTyr: 0.637 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	14.945LeuAla: 14.945 ± 0.168	1.153LeuCys: 1.153 ± 0.044	7.846LeuAsp: 7.846 ± 0.118	7.068LeuGlu: 7.068 ± 0.105	3.826LeuPhe: 3.826 ± 0.075	8.183LeuGly: 8.183 ± 0.092	2.757LeuHis: 2.757 ± 0.065	6.623LeuIle: 6.623 ± 0.099	3.545LeuLys: 3.545 ± 0.082	12.604LeuLeu: 12.604 ± 0.197	2.529LeuMet: 2.529 ± 0.06	3.612LeuAsn: 3.612 ± 0.069	5.963LeuPro: 5.963 ± 0.098	3.959LeuGln: 3.959 ± 0.078	7.986LeuArg: 7.986 ± 0.111	6.313LeuSer: 6.313 ± 0.09	7.381LeuThr: 7.381 ± 0.136	7.486LeuVal: 7.486 ± 0.104	1.344LeuTrp: 1.344 ± 0.045	2.575LeuTyr: 2.575 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.115MetAla: 2.115 ± 0.055	0.151MetCys: 0.151 ± 0.011	1.017MetAsp: 1.017 ± 0.041	0.969MetGlu: 0.969 ± 0.038	0.512MetPhe: 0.512 ± 0.025	1.33MetGly: 1.33 ± 0.038	0.447MetHis: 0.447 ± 0.023	1.101MetIle: 1.101 ± 0.036	0.669MetLys: 0.669 ± 0.028	2.254MetLeu: 2.254 ± 0.057	0.51MetMet: 0.51 ± 0.024	0.797MetAsn: 0.797 ± 0.029	1.295MetPro: 1.295 ± 0.04	0.913MetGln: 0.913 ± 0.031	1.67MetArg: 1.67 ± 0.04	1.376MetSer: 1.376 ± 0.038	1.418MetThr: 1.418 ± 0.041	1.208MetVal: 1.208 ± 0.041	0.139MetTrp: 0.139 ± 0.011	0.3MetTyr: 0.3 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.191AsnAla: 3.191 ± 0.07	0.302AsnCys: 0.302 ± 0.02	1.426AsnAsp: 1.426 ± 0.058	1.3AsnGlu: 1.3 ± 0.042	0.889AsnPhe: 0.889 ± 0.035	2.266AsnGly: 2.266 ± 0.074	0.69AsnHis: 0.69 ± 0.03	1.43AsnIle: 1.43 ± 0.048	0.816AsnLys: 0.816 ± 0.042	3.268AsnLeu: 3.268 ± 0.074	0.556AsnMet: 0.556 ± 0.028	0.84AsnAsn: 0.84 ± 0.044	1.889AsnPro: 1.889 ± 0.054	1.332AsnGln: 1.332 ± 0.044	2.021AsnArg: 2.021 ± 0.048	1.314AsnSer: 1.314 ± 0.048	1.557AsnThr: 1.557 ± 0.046	1.555AsnVal: 1.555 ± 0.061	0.409AsnTrp: 0.409 ± 0.022	0.753AsnTyr: 0.753 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	5.564ProAla: 5.564 ± 0.109	0.439ProCys: 0.439 ± 0.022	3.576ProAsp: 3.576 ± 0.061	4.214ProGlu: 4.214 ± 0.074	1.752ProPhe: 1.752 ± 0.048	3.18ProGly: 3.18 ± 0.069	1.263ProHis: 1.263 ± 0.044	2.523ProIle: 2.523 ± 0.056	1.379ProLys: 1.379 ± 0.043	5.956ProLeu: 5.956 ± 0.118	0.943ProMet: 0.943 ± 0.034	1.622ProAsn: 1.622 ± 0.05	3.01ProPro: 3.01 ± 0.084	1.795ProGln: 1.795 ± 0.058	2.994ProArg: 2.994 ± 0.065	2.632ProSer: 2.632 ± 0.056	3.084ProThr: 3.084 ± 0.071	3.764ProVal: 3.764 ± 0.086	0.692ProTrp: 0.692 ± 0.027	1.232ProTyr: 1.232 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	5.669GlnAla: 5.669 ± 0.091	0.426GlnCys: 0.426 ± 0.026	1.888GlnAsp: 1.888 ± 0.051	1.836GlnGlu: 1.836 ± 0.053	1.424GlnPhe: 1.424 ± 0.04	2.696GlnGly: 2.696 ± 0.052	1.281GlnHis: 1.281 ± 0.039	2.551GlnIle: 2.551 ± 0.058	0.884GlnLys: 0.884 ± 0.037	5.36GlnLeu: 5.36 ± 0.095	0.879GlnMet: 0.879 ± 0.035	0.956GlnAsn: 0.956 ± 0.036	2.493GlnPro: 2.493 ± 0.066	2.294GlnGln: 2.294 ± 0.058	4.254GlnArg: 4.254 ± 0.085	2.004GlnSer: 2.004 ± 0.052	2.451GlnThr: 2.451 ± 0.07	3.246GlnVal: 3.246 ± 0.068	0.499GlnTrp: 0.499 ± 0.026	0.89GlnTyr: 0.89 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	7.76ArgAla: 7.76 ± 0.13	0.759ArgCys: 0.759 ± 0.035	4.228ArgAsp: 4.228 ± 0.082	4.882ArgGlu: 4.882 ± 0.078	3.024ArgPhe: 3.024 ± 0.062	4.317ArgGly: 4.317 ± 0.078	2.049ArgHis: 2.049 ± 0.058	3.956ArgIle: 3.956 ± 0.067	1.688ArgLys: 1.688 ± 0.055	10.299ArgLeu: 10.299 ± 0.145	1.505ArgMet: 1.505 ± 0.042	1.762ArgAsn: 1.762 ± 0.047	3.414ArgPro: 3.414 ± 0.067	3.639ArgGln: 3.639 ± 0.07	5.67ArgArg: 5.67 ± 0.096	3.118ArgSer: 3.118 ± 0.062	3.696ArgThr: 3.696 ± 0.072	5.203ArgVal: 5.203 ± 0.082	1.186ArgTrp: 1.186 ± 0.043	2.147ArgTyr: 2.147 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	5.818SerAla: 5.818 ± 0.082	0.465SerCys: 0.465 ± 0.024	2.959SerAsp: 2.959 ± 0.064	3.079SerGlu: 3.079 ± 0.071	1.734SerPhe: 1.734 ± 0.051	5.019SerGly: 5.019 ± 0.078	1.118SerHis: 1.118 ± 0.032	2.508SerIle: 2.508 ± 0.063	1.371SerLys: 1.371 ± 0.041	5.51SerLeu: 5.51 ± 0.082	0.981SerMet: 0.981 ± 0.033	1.448SerAsn: 1.448 ± 0.047	2.351SerPro: 2.351 ± 0.054	1.913SerGln: 1.913 ± 0.053	3.276SerArg: 3.276 ± 0.061	2.734SerSer: 2.734 ± 0.066	2.574SerThr: 2.574 ± 0.049	3.548SerVal: 3.548 ± 0.07	0.659SerTrp: 0.659 ± 0.033	1.201SerTyr: 1.201 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	7.048ThrAla: 7.048 ± 0.12	0.497ThrCys: 0.497 ± 0.026	3.059ThrAsp: 3.059 ± 0.073	2.995ThrGlu: 2.995 ± 0.063	1.639ThrPhe: 1.639 ± 0.049	4.319ThrGly: 4.319 ± 0.093	1.408ThrHis: 1.408 ± 0.039	2.52ThrIle: 2.52 ± 0.059	1.227ThrLys: 1.227 ± 0.044	7.488ThrLeu: 7.488 ± 0.123	0.764ThrMet: 0.764 ± 0.029	1.345ThrAsn: 1.345 ± 0.055	3.639ThrPro: 3.639 ± 0.073	2.367ThrGln: 2.367 ± 0.052	3.701ThrArg: 3.701 ± 0.069	2.441ThrSer: 2.441 ± 0.058	2.929ThrThr: 2.929 ± 0.076	3.896ThrVal: 3.896 ± 0.084	0.679ThrTrp: 0.679 ± 0.027	1.144ThrTyr: 1.144 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	7.588ValAla: 7.588 ± 0.113	0.765ValCys: 0.765 ± 0.035	3.565ValAsp: 3.565 ± 0.074	4.235ValGlu: 4.235 ± 0.079	2.325ValPhe: 2.325 ± 0.054	4.518ValGly: 4.518 ± 0.071	1.3ValHis: 1.3 ± 0.041	3.947ValIle: 3.947 ± 0.072	2.016ValLys: 2.016 ± 0.068	7.71ValLeu: 7.71 ± 0.103	1.666ValMet: 1.666 ± 0.048	1.932ValAsn: 1.932 ± 0.055	3.239ValPro: 3.239 ± 0.064	2.411ValGln: 2.411 ± 0.05	5.126ValArg: 5.126 ± 0.074	3.666ValSer: 3.666 ± 0.071	3.896ValThr: 3.896 ± 0.079	4.773ValVal: 4.773 ± 0.097	0.84ValTrp: 0.84 ± 0.034	1.499ValTyr: 1.499 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.116TrpAla: 1.116 ± 0.038	0.181TrpCys: 0.181 ± 0.015	0.6TrpAsp: 0.6 ± 0.028	0.653TrpGlu: 0.653 ± 0.035	0.529TrpPhe: 0.529 ± 0.025	0.765TrpGly: 0.765 ± 0.032	0.341TrpHis: 0.341 ± 0.021	0.84TrpIle: 0.84 ± 0.031	0.357TrpLys: 0.357 ± 0.022	2.186TrpLeu: 2.186 ± 0.059	0.33TrpMet: 0.33 ± 0.02	0.437TrpAsn: 0.437 ± 0.018	0.687TrpPro: 0.687 ± 0.03	0.651TrpGln: 0.651 ± 0.03	1.233TrpArg: 1.233 ± 0.044	0.828TrpSer: 0.828 ± 0.035	0.636TrpThr: 0.636 ± 0.027	0.917TrpVal: 0.917 ± 0.035	0.241TrpTrp: 0.241 ± 0.019	0.309TrpTyr: 0.309 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.396TyrAla: 2.396 ± 0.048	0.319TyrCys: 0.319 ± 0.016	1.332TyrAsp: 1.332 ± 0.039	1.205TyrGlu: 1.205 ± 0.038	1.004TyrPhe: 1.004 ± 0.037	1.867TyrGly: 1.867 ± 0.048	0.597TyrHis: 0.597 ± 0.027	1.019TyrIle: 1.019 ± 0.038	0.634TyrLys: 0.634 ± 0.032	2.996TyrLeu: 2.996 ± 0.064	0.412TyrMet: 0.412 ± 0.02	0.659TyrAsn: 0.659 ± 0.027	1.259TyrPro: 1.259 ± 0.04	1.251TyrGln: 1.251 ± 0.042	2.231TyrArg: 2.231 ± 0.045	1.374TyrSer: 1.374 ± 0.045	1.142TyrThr: 1.142 ± 0.042	1.464TyrVal: 1.464 ± 0.042	0.418TyrTrp: 0.418 ± 0.021	0.697TyrTyr: 0.697 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2689 proteins (889806 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---