Amino acid dipepetide frequency for Tomato spotted wilt virus (strain Brazilian Br-01) (TSWV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.192AlaAla: 1.192 ± 0.529
1.192AlaCys: 1.192 ± 0.493
2.782AlaAsp: 2.782 ± 0.661
1.789AlaGlu: 1.789 ± 0.461
2.385AlaPhe: 2.385 ± 0.954
0.994AlaGly: 0.994 ± 0.445
0.596AlaHis: 0.596 ± 0.368
3.18AlaIle: 3.18 ± 1.39
3.975AlaLys: 3.975 ± 1.82
4.571AlaLeu: 4.571 ± 0.907
0.994AlaMet: 0.994 ± 1.171
2.186AlaAsn: 2.186 ± 0.554
0.994AlaPro: 0.994 ± 0.638
1.391AlaGln: 1.391 ± 0.351
1.789AlaArg: 1.789 ± 0.738
4.769AlaSer: 4.769 ± 0.823
2.186AlaThr: 2.186 ± 0.68
1.987AlaVal: 1.987 ± 0.685
0.397AlaTrp: 0.397 ± 0.423
1.59AlaTyr: 1.59 ± 0.639
0.0AlaXaa: 0.0 ± 0.0
Cys
0.397CysAla: 0.397 ± 0.174
0.199CysCys: 0.199 ± 0.486
0.795CysAsp: 0.795 ± 0.348
0.994CysGlu: 0.994 ± 0.535
1.59CysPhe: 1.59 ± 0.366
1.192CysGly: 1.192 ± 0.994
0.199CysHis: 0.199 ± 0.122
2.782CysIle: 2.782 ± 1.177
1.59CysLys: 1.59 ± 1.019
3.18CysLeu: 3.18 ± 0.802
0.397CysMet: 0.397 ± 0.439
1.192CysAsn: 1.192 ± 0.554
1.391CysPro: 1.391 ± 0.774
0.397CysGln: 0.397 ± 0.439
0.596CysArg: 0.596 ± 0.635
2.186CysSer: 2.186 ± 1.057
0.596CysThr: 0.596 ± 0.663
1.192CysVal: 1.192 ± 0.366
0.0CysTrp: 0.0 ± 0.0
1.192CysTyr: 1.192 ± 0.349
0.0CysXaa: 0.0 ± 0.0
Asp
2.186AspAla: 2.186 ± 0.987
1.192AspCys: 1.192 ± 0.735
3.18AspAsp: 3.18 ± 0.553
5.167AspGlu: 5.167 ± 1.671
3.577AspPhe: 3.577 ± 0.548
1.391AspGly: 1.391 ± 0.705
1.192AspHis: 1.192 ± 0.426
5.366AspIle: 5.366 ± 1.914
3.776AspLys: 3.776 ± 0.714
6.359AspLeu: 6.359 ± 0.251
1.987AspMet: 1.987 ± 0.547
2.583AspAsn: 2.583 ± 0.761
1.59AspPro: 1.59 ± 1.07
1.789AspGln: 1.789 ± 1.462
1.59AspArg: 1.59 ± 0.586
6.757AspSer: 6.757 ± 1.293
2.981AspThr: 2.981 ± 0.501
2.186AspVal: 2.186 ± 0.863
0.199AspTrp: 0.199 ± 0.122
1.789AspTyr: 1.789 ± 0.638
0.0AspXaa: 0.0 ± 0.0
Glu
2.583GluAla: 2.583 ± 0.701
1.59GluCys: 1.59 ± 0.42
5.962GluAsp: 5.962 ± 1.994
6.161GluGlu: 6.161 ± 1.473
2.385GluPhe: 2.385 ± 0.753
3.18GluGly: 3.18 ± 1.518
1.789GluHis: 1.789 ± 0.461
6.558GluIle: 6.558 ± 2.24
5.366GluLys: 5.366 ± 1.084
5.962GluLeu: 5.962 ± 1.698
2.186GluMet: 2.186 ± 1.386
5.763GluAsn: 5.763 ± 0.792
1.192GluPro: 1.192 ± 0.57
1.192GluGln: 1.192 ± 0.521
2.782GluArg: 2.782 ± 1.161
4.173GluSer: 4.173 ± 0.965
4.571GluThr: 4.571 ± 0.905
3.18GluVal: 3.18 ± 0.824
0.795GluTrp: 0.795 ± 0.283
2.583GluTyr: 2.583 ± 0.61
0.0GluXaa: 0.0 ± 0.0
Phe
1.192PheAla: 1.192 ± 0.644
1.59PheCys: 1.59 ± 0.71
2.385PheAsp: 2.385 ± 0.444
3.18PheGlu: 3.18 ± 1.374
1.789PhePhe: 1.789 ± 0.668
3.18PheGly: 3.18 ± 1.996
0.795PheHis: 0.795 ± 0.3
1.987PheIle: 1.987 ± 0.441
3.975PheLys: 3.975 ± 0.99
5.366PheLeu: 5.366 ± 1.268
0.596PheMet: 0.596 ± 0.213
2.782PheAsn: 2.782 ± 0.886
1.391PhePro: 1.391 ± 0.375
1.192PheGln: 1.192 ± 0.366
2.583PheArg: 2.583 ± 0.683
5.167PheSer: 5.167 ± 1.633
1.192PheThr: 1.192 ± 0.622
2.186PheVal: 2.186 ± 0.699
0.199PheTrp: 0.199 ± 0.212
1.192PheTyr: 1.192 ± 0.854
0.0PheXaa: 0.0 ± 0.0
Gly
0.596GlyAla: 0.596 ± 0.213
1.192GlyCys: 1.192 ± 0.994
1.987GlyAsp: 1.987 ± 0.863
3.18GlyGlu: 3.18 ± 0.91
2.583GlyPhe: 2.583 ± 0.927
2.186GlyGly: 2.186 ± 1.113
0.397GlyHis: 0.397 ± 0.396
2.981GlyIle: 2.981 ± 0.71
5.167GlyLys: 5.167 ± 3.13
4.769GlyLeu: 4.769 ± 1.335
1.59GlyMet: 1.59 ± 0.752
2.583GlyAsn: 2.583 ± 0.847
0.795GlyPro: 0.795 ± 0.497
0.795GlyGln: 0.795 ± 0.497
1.391GlyArg: 1.391 ± 0.852
4.968GlySer: 4.968 ± 1.292
3.378GlyThr: 3.378 ± 1.096
1.391GlyVal: 1.391 ± 0.744
0.199GlyTrp: 0.199 ± 0.122
1.192GlyTyr: 1.192 ± 0.554
0.0GlyXaa: 0.0 ± 0.0
His
0.795HisAla: 0.795 ± 0.487
0.0HisCys: 0.0 ± 0.0
2.186HisAsp: 2.186 ± 0.68
0.994HisGlu: 0.994 ± 0.711
1.391HisPhe: 1.391 ± 0.433
0.397HisGly: 0.397 ± 0.174
0.199HisHis: 0.199 ± 0.486
1.192HisIle: 1.192 ± 0.366
0.795HisLys: 0.795 ± 0.459
1.391HisLeu: 1.391 ± 0.401
0.199HisMet: 0.199 ± 0.122
1.987HisAsn: 1.987 ± 0.306
1.192HisPro: 1.192 ± 0.454
0.397HisGln: 0.397 ± 0.663
0.397HisArg: 0.397 ± 0.244
0.795HisSer: 0.795 ± 0.283
0.795HisThr: 0.795 ± 0.63
0.795HisVal: 0.795 ± 0.357
0.199HisTrp: 0.199 ± 0.122
0.596HisTyr: 0.596 ± 0.508
0.0HisXaa: 0.0 ± 0.0
Ile
4.173IleAla: 4.173 ± 0.925
1.192IleCys: 1.192 ± 0.985
2.981IleAsp: 2.981 ± 1.249
6.955IleGlu: 6.955 ± 1.441
3.18IlePhe: 3.18 ± 0.998
2.583IleGly: 2.583 ± 0.683
0.795IleHis: 0.795 ± 0.283
5.366IleIle: 5.366 ± 0.879
7.75IleLys: 7.75 ± 1.261
6.558IleLeu: 6.558 ± 1.26
2.385IleMet: 2.385 ± 0.961
4.372IleAsn: 4.372 ± 1.744
4.372IlePro: 4.372 ± 1.712
2.981IleGln: 2.981 ± 0.645
4.769IleArg: 4.769 ± 0.748
6.558IleSer: 6.558 ± 1.026
5.167IleThr: 5.167 ± 1.149
3.975IleVal: 3.975 ± 0.467
0.795IleTrp: 0.795 ± 0.441
4.372IleTyr: 4.372 ± 1.067
0.0IleXaa: 0.0 ± 0.0
Lys
3.975LysAla: 3.975 ± 0.763
1.987LysCys: 1.987 ± 1.172
3.975LysAsp: 3.975 ± 0.923
6.558LysGlu: 6.558 ± 1.341
2.981LysPhe: 2.981 ± 0.494
4.769LysGly: 4.769 ± 1.193
1.59LysHis: 1.59 ± 0.576
6.757LysIle: 6.757 ± 0.509
9.539LysLys: 9.539 ± 1.455
7.949LysLeu: 7.949 ± 1.129
3.18LysMet: 3.18 ± 0.367
4.372LysAsn: 4.372 ± 1.292
2.186LysPro: 2.186 ± 0.518
3.577LysGln: 3.577 ± 2.443
2.782LysArg: 2.782 ± 0.542
8.347LysSer: 8.347 ± 1.165
4.372LysThr: 4.372 ± 0.717
5.366LysVal: 5.366 ± 2.134
0.596LysTrp: 0.596 ± 0.213
2.981LysTyr: 2.981 ± 0.97
0.0LysXaa: 0.0 ± 0.0
Leu
5.763LeuAla: 5.763 ± 1.759
1.59LeuCys: 1.59 ± 0.577
5.167LeuAsp: 5.167 ± 0.929
7.154LeuGlu: 7.154 ± 0.817
4.769LeuPhe: 4.769 ± 0.934
4.173LeuGly: 4.173 ± 1.195
1.987LeuHis: 1.987 ± 0.546
7.949LeuIle: 7.949 ± 1.571
7.75LeuLys: 7.75 ± 0.837
7.75LeuLeu: 7.75 ± 1.407
3.18LeuMet: 3.18 ± 0.666
6.757LeuAsn: 6.757 ± 0.688
2.782LeuPro: 2.782 ± 0.879
2.186LeuGln: 2.186 ± 0.764
3.776LeuArg: 3.776 ± 1.813
11.129LeuSer: 11.129 ± 2.067
6.558LeuThr: 6.558 ± 1.05
4.968LeuVal: 4.968 ± 0.778
0.994LeuTrp: 0.994 ± 1.087
3.378LeuTyr: 3.378 ± 0.98
0.0LeuXaa: 0.0 ± 0.0
Met
0.596MetAla: 0.596 ± 0.213
0.397MetCys: 0.397 ± 0.615
0.994MetAsp: 0.994 ± 0.418
1.987MetGlu: 1.987 ± 0.736
1.192MetPhe: 1.192 ± 0.529
0.994MetGly: 0.994 ± 0.369
0.397MetHis: 0.397 ± 0.244
2.186MetIle: 2.186 ± 0.922
1.789MetLys: 1.789 ± 0.642
3.776MetLeu: 3.776 ± 0.377
1.391MetMet: 1.391 ± 0.513
2.186MetAsn: 2.186 ± 0.737
0.994MetPro: 0.994 ± 0.445
0.596MetGln: 0.596 ± 0.365
1.192MetArg: 1.192 ± 0.518
2.782MetSer: 2.782 ± 0.948
1.987MetThr: 1.987 ± 0.556
0.994MetVal: 0.994 ± 0.418
0.199MetTrp: 0.199 ± 0.122
1.192MetTyr: 1.192 ± 0.561
0.0MetXaa: 0.0 ± 0.0
Asn
2.583AsnAla: 2.583 ± 0.593
2.583AsnCys: 2.583 ± 0.881
4.173AsnAsp: 4.173 ± 0.912
3.577AsnGlu: 3.577 ± 1.032
2.583AsnPhe: 2.583 ± 0.404
2.981AsnGly: 2.981 ± 0.726
0.994AsnHis: 0.994 ± 0.469
5.564AsnIle: 5.564 ± 0.643
5.962AsnLys: 5.962 ± 0.437
6.955AsnLeu: 6.955 ± 1.194
0.795AsnMet: 0.795 ± 0.441
3.776AsnAsn: 3.776 ± 0.792
1.987AsnPro: 1.987 ± 0.527
1.987AsnGln: 1.987 ± 0.587
1.789AsnArg: 1.789 ± 1.058
3.975AsnSer: 3.975 ± 0.779
3.378AsnThr: 3.378 ± 0.493
3.975AsnVal: 3.975 ± 1.162
0.795AsnTrp: 0.795 ± 0.878
2.385AsnTyr: 2.385 ± 0.979
0.0AsnXaa: 0.0 ± 0.0
Pro
0.795ProAla: 0.795 ± 0.357
0.397ProCys: 0.397 ± 0.244
1.391ProAsp: 1.391 ± 0.536
2.583ProGlu: 2.583 ± 0.881
1.391ProPhe: 1.391 ± 0.375
1.192ProGly: 1.192 ± 0.57
0.0ProHis: 0.0 ± 0.0
3.378ProIle: 3.378 ± 1.033
2.583ProLys: 2.583 ± 0.977
2.981ProLeu: 2.981 ± 1.692
0.795ProMet: 0.795 ± 0.721
2.981ProAsn: 2.981 ± 1.694
0.199ProPro: 0.199 ± 0.212
0.795ProGln: 0.795 ± 0.283
0.596ProArg: 0.596 ± 0.419
2.782ProSer: 2.782 ± 0.978
2.385ProThr: 2.385 ± 1.164
1.987ProVal: 1.987 ± 0.651
0.199ProTrp: 0.199 ± 0.486
0.994ProTyr: 0.994 ± 0.397
0.0ProXaa: 0.0 ± 0.0
Gln
2.186GlnAla: 2.186 ± 1.255
0.596GlnCys: 0.596 ± 0.635
1.789GlnAsp: 1.789 ± 0.489
0.795GlnGlu: 0.795 ± 0.786
0.596GlnPhe: 0.596 ± 0.365
1.391GlnGly: 1.391 ± 0.744
0.397GlnHis: 0.397 ± 0.294
2.583GlnIle: 2.583 ± 0.356
1.59GlnLys: 1.59 ± 0.531
2.782GlnLeu: 2.782 ± 1.97
0.596GlnMet: 0.596 ± 0.213
1.789GlnAsn: 1.789 ± 0.515
0.0GlnPro: 0.0 ± 0.0
0.994GlnGln: 0.994 ± 0.405
1.192GlnArg: 1.192 ± 0.518
2.583GlnSer: 2.583 ± 0.742
2.583GlnThr: 2.583 ± 0.842
1.391GlnVal: 1.391 ± 0.903
0.199GlnTrp: 0.199 ± 0.122
0.596GlnTyr: 0.596 ± 0.419
0.0GlnXaa: 0.0 ± 0.0
Arg
1.391ArgAla: 1.391 ± 1.361
0.0ArgCys: 0.0 ± 0.0
1.987ArgAsp: 1.987 ± 0.991
3.18ArgGlu: 3.18 ± 1.504
1.192ArgPhe: 1.192 ± 0.644
1.192ArgGly: 1.192 ± 0.349
0.994ArgHis: 0.994 ± 0.405
3.378ArgIle: 3.378 ± 0.755
2.186ArgLys: 2.186 ± 0.571
4.372ArgLeu: 4.372 ± 1.537
0.795ArgMet: 0.795 ± 0.441
3.18ArgAsn: 3.18 ± 1.064
0.994ArgPro: 0.994 ± 0.418
1.192ArgGln: 1.192 ± 0.622
1.391ArgArg: 1.391 ± 0.433
2.782ArgSer: 2.782 ± 0.701
2.981ArgThr: 2.981 ± 1.159
1.59ArgVal: 1.59 ± 0.369
0.795ArgTrp: 0.795 ± 0.3
1.59ArgTyr: 1.59 ± 0.752
0.0ArgXaa: 0.0 ± 0.0
Ser
2.981SerAla: 2.981 ± 1.196
2.186SerCys: 2.186 ± 0.377
5.962SerAsp: 5.962 ± 0.847
6.161SerGlu: 6.161 ± 1.07
4.173SerPhe: 4.173 ± 0.901
4.769SerGly: 4.769 ± 0.944
1.391SerHis: 1.391 ± 0.439
7.75SerIle: 7.75 ± 2.078
8.347SerLys: 8.347 ± 0.866
10.135SerLeu: 10.135 ± 1.394
1.789SerMet: 1.789 ± 0.492
4.173SerAsn: 4.173 ± 0.665
2.583SerPro: 2.583 ± 0.735
1.987SerGln: 1.987 ± 1.139
3.378SerArg: 3.378 ± 0.665
8.148SerSer: 8.148 ± 1.384
4.571SerThr: 4.571 ± 1.335
7.75SerVal: 7.75 ± 3.221
0.795SerTrp: 0.795 ± 0.704
4.372SerTyr: 4.372 ± 1.159
0.0SerXaa: 0.0 ± 0.0
Thr
2.981ThrAla: 2.981 ± 0.857
1.789ThrCys: 1.789 ± 0.706
3.378ThrAsp: 3.378 ± 0.493
2.583ThrGlu: 2.583 ± 1.002
2.981ThrPhe: 2.981 ± 1.818
2.782ThrGly: 2.782 ± 0.23
1.192ThrHis: 1.192 ± 0.57
4.173ThrIle: 4.173 ± 1.31
4.372ThrLys: 4.372 ± 0.96
4.571ThrLeu: 4.571 ± 0.461
1.987ThrMet: 1.987 ± 0.581
2.981ThrAsn: 2.981 ± 0.512
1.59ThrPro: 1.59 ± 0.33
1.59ThrGln: 1.59 ± 0.815
2.186ThrArg: 2.186 ± 0.68
5.564ThrSer: 5.564 ± 1.117
3.18ThrThr: 3.18 ± 1.2
3.975ThrVal: 3.975 ± 0.796
0.199ThrTrp: 0.199 ± 0.486
3.577ThrTyr: 3.577 ± 0.743
0.0ThrXaa: 0.0 ± 0.0
Val
2.782ValAla: 2.782 ± 1.941
1.59ValCys: 1.59 ± 0.639
2.782ValAsp: 2.782 ± 0.399
4.173ValGlu: 4.173 ± 0.43
1.192ValPhe: 1.192 ± 0.561
2.385ValGly: 2.385 ± 0.343
0.994ValHis: 0.994 ± 0.584
4.968ValIle: 4.968 ± 1.77
5.962ValLys: 5.962 ± 1.198
5.167ValLeu: 5.167 ± 1.131
1.391ValMet: 1.391 ± 0.45
3.577ValAsn: 3.577 ± 1.047
2.186ValPro: 2.186 ± 0.959
0.596ValGln: 0.596 ± 0.303
1.59ValArg: 1.59 ± 0.929
4.571ValSer: 4.571 ± 0.891
2.583ValThr: 2.583 ± 1.051
3.18ValVal: 3.18 ± 0.344
0.596ValTrp: 0.596 ± 0.303
1.987ValTyr: 1.987 ± 0.685
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.199TrpCys: 0.199 ± 0.212
0.795TrpAsp: 0.795 ± 0.497
0.397TrpGlu: 0.397 ± 0.244
0.397TrpPhe: 0.397 ± 0.174
0.596TrpGly: 0.596 ± 0.542
0.0TrpHis: 0.0 ± 0.0
0.795TrpIle: 0.795 ± 0.283
1.192TrpLys: 1.192 ± 0.382
1.391TrpLeu: 1.391 ± 1.226
0.199TrpMet: 0.199 ± 0.122
0.397TrpAsn: 0.397 ± 0.244
0.0TrpPro: 0.0 ± 0.0
0.199TrpGln: 0.199 ± 0.122
0.199TrpArg: 0.199 ± 0.122
0.795TrpSer: 0.795 ± 0.878
0.596TrpThr: 0.596 ± 0.419
0.199TrpVal: 0.199 ± 0.486
0.0TrpTrp: 0.0 ± 0.0
0.199TrpTyr: 0.199 ± 0.212
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.789TyrAla: 1.789 ± 0.427
0.596TyrCys: 0.596 ± 0.322
2.186TyrAsp: 2.186 ± 0.616
2.385TyrGlu: 2.385 ± 0.368
1.59TyrPhe: 1.59 ± 0.707
0.994TyrGly: 0.994 ± 0.554
0.795TyrHis: 0.795 ± 0.487
2.583TyrIle: 2.583 ± 0.777
4.173TyrLys: 4.173 ± 0.868
3.776TyrLeu: 3.776 ± 1.021
1.192TyrMet: 1.192 ± 0.366
3.18TyrAsn: 3.18 ± 1.186
1.987TyrPro: 1.987 ± 0.651
0.795TyrGln: 0.795 ± 0.576
1.192TyrArg: 1.192 ± 0.521
4.571TyrSer: 4.571 ± 0.361
1.59TyrThr: 1.59 ± 0.499
1.987TyrVal: 1.987 ± 0.811
0.397TyrTrp: 0.397 ± 0.396
0.994TyrTyr: 0.994 ± 0.405
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (5033 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski