Amino acid dipepetide frequency for Kibdelosporangium aridum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.479AlaAla: 17.479 ± 0.11	1.023AlaCys: 1.023 ± 0.018	7.584AlaAsp: 7.584 ± 0.048	7.925AlaGlu: 7.925 ± 0.063	3.488AlaPhe: 3.488 ± 0.038	11.13AlaGly: 11.13 ± 0.068	2.343AlaHis: 2.343 ± 0.028	4.886AlaIle: 4.886 ± 0.039	3.454AlaLys: 3.454 ± 0.037	12.732AlaLeu: 12.732 ± 0.077	2.753AlaMet: 2.753 ± 0.029	2.775AlaAsn: 2.775 ± 0.032	5.327AlaPro: 5.327 ± 0.038	3.954AlaGln: 3.954 ± 0.038	8.289AlaArg: 8.289 ± 0.054	6.121AlaSer: 6.121 ± 0.043	7.061AlaThr: 7.061 ± 0.048	11.019AlaVal: 11.019 ± 0.068	1.813AlaTrp: 1.813 ± 0.022	2.426AlaTyr: 2.426 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.968CysAla: 0.968 ± 0.017	0.1CysCys: 0.1 ± 0.005	0.507CysAsp: 0.507 ± 0.011	0.425CysGlu: 0.425 ± 0.011	0.24CysPhe: 0.24 ± 0.009	0.897CysGly: 0.897 ± 0.016	0.205CysHis: 0.205 ± 0.007	0.186CysIle: 0.186 ± 0.008	0.142CysLys: 0.142 ± 0.007	0.733CysLeu: 0.733 ± 0.014	0.141CysMet: 0.141 ± 0.006	0.157CysAsn: 0.157 ± 0.007	0.478CysPro: 0.478 ± 0.012	0.228CysGln: 0.228 ± 0.008	0.58CysArg: 0.58 ± 0.014	0.502CysSer: 0.502 ± 0.012	0.5CysThr: 0.5 ± 0.011	0.661CysVal: 0.661 ± 0.014	0.127CysTrp: 0.127 ± 0.006	0.188CysTyr: 0.188 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	6.669AspAla: 6.669 ± 0.044	0.417AspCys: 0.417 ± 0.011	3.453AspAsp: 3.453 ± 0.033	3.841AspGlu: 3.841 ± 0.039	1.774AspPhe: 1.774 ± 0.023	5.764AspGly: 5.764 ± 0.047	1.417AspHis: 1.417 ± 0.023	2.332AspIle: 2.332 ± 0.024	1.521AspLys: 1.521 ± 0.024	6.237AspLeu: 6.237 ± 0.047	1.008AspMet: 1.008 ± 0.017	1.397AspAsn: 1.397 ± 0.022	4.244AspPro: 4.244 ± 0.038	1.931AspGln: 1.931 ± 0.022	4.612AspArg: 4.612 ± 0.039	2.783AspSer: 2.783 ± 0.03	3.076AspThr: 3.076 ± 0.032	5.286AspVal: 5.286 ± 0.038	1.02AspTrp: 1.02 ± 0.019	1.308AspTyr: 1.308 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	6.044GluAla: 6.044 ± 0.051	0.371GluCys: 0.371 ± 0.01	2.493GluAsp: 2.493 ± 0.027	2.573GluGlu: 2.573 ± 0.033	1.753GluPhe: 1.753 ± 0.023	3.254GluGly: 3.254 ± 0.036	1.543GluHis: 1.543 ± 0.022	2.603GluIle: 2.603 ± 0.028	1.359GluLys: 1.359 ± 0.022	6.827GluLeu: 6.827 ± 0.053	1.007GluMet: 1.007 ± 0.016	1.234GluAsn: 1.234 ± 0.018	3.152GluPro: 3.152 ± 0.035	2.46GluGln: 2.46 ± 0.029	4.548GluArg: 4.548 ± 0.038	2.561GluSer: 2.561 ± 0.027	2.745GluThr: 2.745 ± 0.024	4.533GluVal: 4.533 ± 0.035	0.872GluTrp: 0.872 ± 0.017	1.139GluTyr: 1.139 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.84PheAla: 3.84 ± 0.035	0.269PheCys: 0.269 ± 0.008	2.336PheAsp: 2.336 ± 0.03	1.532PheGlu: 1.532 ± 0.021	0.95PhePhe: 0.95 ± 0.02	3.301PheGly: 3.301 ± 0.031	0.644PheHis: 0.644 ± 0.015	0.96PheIle: 0.96 ± 0.018	0.56PheLys: 0.56 ± 0.014	2.675PheLeu: 2.675 ± 0.03	0.453PheMet: 0.453 ± 0.012	0.729PheAsn: 0.729 ± 0.014	1.493PhePro: 1.493 ± 0.02	0.842PheGln: 0.842 ± 0.015	1.909PheArg: 1.909 ± 0.024	1.706PheSer: 1.706 ± 0.022	2.21PheThr: 2.21 ± 0.026	2.614PheVal: 2.614 ± 0.03	0.463PheTrp: 0.463 ± 0.01	0.686PheTyr: 0.686 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	8.832GlyAla: 8.832 ± 0.06	0.799GlyCys: 0.799 ± 0.015	4.721GlyAsp: 4.721 ± 0.038	4.481GlyGlu: 4.481 ± 0.037	2.959GlyPhe: 2.959 ± 0.028	7.318GlyGly: 7.318 ± 0.068	2.072GlyHis: 2.072 ± 0.027	3.889GlyIle: 3.889 ± 0.032	2.837GlyLys: 2.837 ± 0.035	8.788GlyLeu: 8.788 ± 0.055	2.118GlyMet: 2.118 ± 0.026	2.226GlyAsn: 2.226 ± 0.029	4.366GlyPro: 4.366 ± 0.038	3.017GlyGln: 3.017 ± 0.029	6.125GlyArg: 6.125 ± 0.043	4.966GlySer: 4.966 ± 0.04	5.718GlyThr: 5.718 ± 0.048	7.472GlyVal: 7.472 ± 0.063	1.698GlyTrp: 1.698 ± 0.024	2.374GlyTyr: 2.374 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.491HisAla: 2.491 ± 0.028	0.222HisCys: 0.222 ± 0.007	1.321HisAsp: 1.321 ± 0.021	1.184HisGlu: 1.184 ± 0.017	0.638HisPhe: 0.638 ± 0.015	2.152HisGly: 2.152 ± 0.028	0.645HisHis: 0.645 ± 0.015	0.791HisIle: 0.791 ± 0.014	0.458HisLys: 0.458 ± 0.011	2.15HisLeu: 2.15 ± 0.025	0.362HisMet: 0.362 ± 0.01	0.544HisAsn: 0.544 ± 0.014	1.554HisPro: 1.554 ± 0.023	0.731HisGln: 0.731 ± 0.014	1.829HisArg: 1.829 ± 0.023	1.077HisSer: 1.077 ± 0.017	1.201HisThr: 1.201 ± 0.019	1.841HisVal: 1.841 ± 0.021	0.366HisTrp: 0.366 ± 0.008	0.517HisTyr: 0.517 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	5.82IleAla: 5.82 ± 0.046	0.34IleCys: 0.34 ± 0.01	2.879IleAsp: 2.879 ± 0.032	2.443IleGlu: 2.443 ± 0.026	0.946IlePhe: 0.946 ± 0.017	4.276IleGly: 4.276 ± 0.042	0.705IleHis: 0.705 ± 0.014	1.231IleIle: 1.231 ± 0.02	0.995IleLys: 0.995 ± 0.018	2.99IleLeu: 2.99 ± 0.03	0.571IleMet: 0.571 ± 0.013	1.024IleAsn: 1.024 ± 0.018	2.205IlePro: 2.205 ± 0.024	1.023IleGln: 1.023 ± 0.018	2.785IleArg: 2.785 ± 0.024	2.302IleSer: 2.302 ± 0.025	2.904IleThr: 2.904 ± 0.03	3.585IleVal: 3.585 ± 0.035	0.528IleTrp: 0.528 ± 0.012	0.746IleTyr: 0.746 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	3.137LysAla: 3.137 ± 0.034	0.154LysCys: 0.154 ± 0.008	1.373LysAsp: 1.373 ± 0.021	1.108LysGlu: 1.108 ± 0.021	0.729LysPhe: 0.729 ± 0.015	1.661LysGly: 1.661 ± 0.026	0.608LysHis: 0.608 ± 0.011	1.182LysIle: 1.182 ± 0.02	0.684LysLys: 0.684 ± 0.016	2.607LysLeu: 2.607 ± 0.03	0.472LysMet: 0.472 ± 0.012	0.569LysAsn: 0.569 ± 0.014	1.798LysPro: 1.798 ± 0.025	0.957LysGln: 0.957 ± 0.017	1.738LysArg: 1.738 ± 0.022	1.326LysSer: 1.326 ± 0.02	1.57LysThr: 1.57 ± 0.022	2.248LysVal: 2.248 ± 0.027	0.396LysTrp: 0.396 ± 0.011	0.572LysTyr: 0.572 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	14.51LeuAla: 14.51 ± 0.084	0.772LeuCys: 0.772 ± 0.015	6.583LeuAsp: 6.583 ± 0.051	4.399LeuGlu: 4.399 ± 0.041	2.768LeuPhe: 2.768 ± 0.033	8.739LeuGly: 8.739 ± 0.056	2.126LeuHis: 2.126 ± 0.025	4.05LeuIle: 4.05 ± 0.038	2.141LeuLys: 2.141 ± 0.028	10.541LeuLeu: 10.541 ± 0.071	1.685LeuMet: 1.685 ± 0.02	2.112LeuAsn: 2.112 ± 0.026	5.95LeuPro: 5.95 ± 0.041	2.441LeuGln: 2.441 ± 0.025	8.113LeuArg: 8.113 ± 0.054	5.861LeuSer: 5.861 ± 0.04	6.715LeuThr: 6.715 ± 0.043	9.14LeuVal: 9.14 ± 0.058	1.338LeuTrp: 1.338 ± 0.022	1.81LeuTyr: 1.81 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.401MetAla: 2.401 ± 0.029	0.143MetCys: 0.143 ± 0.006	0.995MetAsp: 0.995 ± 0.017	0.683MetGlu: 0.683 ± 0.015	0.588MetPhe: 0.588 ± 0.014	1.297MetGly: 1.297 ± 0.019	0.422MetHis: 0.422 ± 0.011	0.941MetIle: 0.941 ± 0.018	0.466MetLys: 0.466 ± 0.011	2.039MetLeu: 2.039 ± 0.026	0.344MetMet: 0.344 ± 0.011	0.484MetAsn: 0.484 ± 0.011	1.23MetPro: 1.23 ± 0.018	0.514MetGln: 0.514 ± 0.013	1.678MetArg: 1.678 ± 0.02	1.42MetSer: 1.42 ± 0.019	1.688MetThr: 1.688 ± 0.022	1.587MetVal: 1.587 ± 0.018	0.245MetTrp: 0.245 ± 0.008	0.359MetTyr: 0.359 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.797AsnAla: 2.797 ± 0.03	0.212AsnCys: 0.212 ± 0.007	1.277AsnAsp: 1.277 ± 0.019	1.14AsnGlu: 1.14 ± 0.017	0.657AsnPhe: 0.657 ± 0.014	2.539AsnGly: 2.539 ± 0.035	0.495AsnHis: 0.495 ± 0.014	0.865AsnIle: 0.865 ± 0.015	0.568AsnLys: 0.568 ± 0.011	2.171AsnLeu: 2.171 ± 0.026	0.376AsnMet: 0.376 ± 0.011	0.713AsnAsn: 0.713 ± 0.018	1.805AsnPro: 1.805 ± 0.021	0.804AsnGln: 0.804 ± 0.017	1.676AsnArg: 1.676 ± 0.022	1.261AsnSer: 1.261 ± 0.022	1.446AsnThr: 1.446 ± 0.023	1.888AsnVal: 1.888 ± 0.023	0.404AsnTrp: 0.404 ± 0.01	0.566AsnTyr: 0.566 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	7.121ProAla: 7.121 ± 0.049	0.341ProCys: 0.341 ± 0.011	4.446ProAsp: 4.446 ± 0.034	3.701ProGlu: 3.701 ± 0.034	1.612ProPhe: 1.612 ± 0.02	5.642ProGly: 5.642 ± 0.048	1.18ProHis: 1.18 ± 0.02	1.981ProIle: 1.981 ± 0.023	1.412ProLys: 1.412 ± 0.021	4.803ProLeu: 4.803 ± 0.043	1.139ProMet: 1.139 ± 0.019	1.399ProAsn: 1.399 ± 0.02	3.484ProPro: 3.484 ± 0.055	1.912ProGln: 1.912 ± 0.027	3.377ProArg: 3.377 ± 0.031	3.283ProSer: 3.283 ± 0.034	3.277ProThr: 3.277 ± 0.033	5.202ProVal: 5.202 ± 0.041	0.884ProTrp: 0.884 ± 0.017	1.166ProTyr: 1.166 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	4.268GlnAla: 4.268 ± 0.044	0.224GlnCys: 0.224 ± 0.007	1.54GlnAsp: 1.54 ± 0.022	1.423GlnGlu: 1.423 ± 0.021	1.003GlnPhe: 1.003 ± 0.017	2.197GlnGly: 2.197 ± 0.027	0.775GlnHis: 0.775 ± 0.015	1.442GlnIle: 1.442 ± 0.019	0.659GlnLys: 0.659 ± 0.015	3.557GlnLeu: 3.557 ± 0.032	0.603GlnMet: 0.603 ± 0.012	0.722GlnAsn: 0.722 ± 0.015	2.187GlnPro: 2.187 ± 0.029	1.589GlnGln: 1.589 ± 0.023	2.852GlnArg: 2.852 ± 0.029	1.519GlnSer: 1.519 ± 0.019	1.677GlnThr: 1.677 ± 0.022	2.815GlnVal: 2.815 ± 0.03	0.579GlnTrp: 0.579 ± 0.013	0.696GlnTyr: 0.696 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	8.19ArgAla: 8.19 ± 0.063	0.59ArgCys: 0.59 ± 0.014	4.21ArgAsp: 4.21 ± 0.038	4.025ArgGlu: 4.025 ± 0.034	2.414ArgPhe: 2.414 ± 0.026	5.062ArgGly: 5.062 ± 0.04	1.82ArgHis: 1.82 ± 0.023	3.424ArgIle: 3.424 ± 0.029	2.014ArgLys: 2.014 ± 0.028	8.055ArgLeu: 8.055 ± 0.052	1.848ArgMet: 1.848 ± 0.023	1.769ArgAsn: 1.769 ± 0.022	4.012ArgPro: 4.012 ± 0.041	2.634ArgGln: 2.634 ± 0.029	6.398ArgArg: 6.398 ± 0.056	3.962ArgSer: 3.962 ± 0.036	4.562ArgThr: 4.562 ± 0.037	5.734ArgVal: 5.734 ± 0.033	1.345ArgTrp: 1.345 ± 0.022	1.86ArgTyr: 1.86 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	6.54SerAla: 6.54 ± 0.051	0.48SerCys: 0.48 ± 0.012	2.934SerAsp: 2.934 ± 0.028	2.502SerGlu: 2.502 ± 0.025	1.711SerPhe: 1.711 ± 0.02	5.839SerGly: 5.839 ± 0.045	1.046SerHis: 1.046 ± 0.018	2.07SerIle: 2.07 ± 0.025	1.287SerLys: 1.287 ± 0.02	5.158SerLeu: 5.158 ± 0.042	1.259SerMet: 1.259 ± 0.018	1.244SerAsn: 1.244 ± 0.021	3.225SerPro: 3.225 ± 0.031	1.615SerGln: 1.615 ± 0.02	3.798SerArg: 3.798 ± 0.032	3.232SerSer: 3.232 ± 0.036	3.65SerThr: 3.65 ± 0.038	4.695SerVal: 4.695 ± 0.04	1.015SerTrp: 1.015 ± 0.017	1.302SerTyr: 1.302 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	7.71ThrAla: 7.71 ± 0.051	0.491ThrCys: 0.491 ± 0.014	3.556ThrAsp: 3.556 ± 0.033	3.219ThrGlu: 3.219 ± 0.027	1.903ThrPhe: 1.903 ± 0.025	6.138ThrGly: 6.138 ± 0.047	1.184ThrHis: 1.184 ± 0.018	2.454ThrIle: 2.454 ± 0.028	1.6ThrLys: 1.6 ± 0.026	5.732ThrLeu: 5.732 ± 0.048	1.216ThrMet: 1.216 ± 0.018	1.427ThrAsn: 1.427 ± 0.02	3.86ThrPro: 3.86 ± 0.034	1.689ThrGln: 1.689 ± 0.025	3.876ThrArg: 3.876 ± 0.029	3.582ThrSer: 3.582 ± 0.033	4.138ThrThr: 4.138 ± 0.043	6.181ThrVal: 6.181 ± 0.043	1.025ThrTrp: 1.025 ± 0.017	1.41ThrTyr: 1.41 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	10.747ValAla: 10.747 ± 0.055	0.665ValCys: 0.665 ± 0.012	5.629ValAsp: 5.629 ± 0.042	4.661ValGlu: 4.661 ± 0.043	2.704ValPhe: 2.704 ± 0.038	6.475ValGly: 6.475 ± 0.048	1.966ValHis: 1.966 ± 0.024	3.697ValIle: 3.697 ± 0.033	1.973ValLys: 1.973 ± 0.023	9.835ValLeu: 9.835 ± 0.067	1.506ValMet: 1.506 ± 0.022	2.103ValAsn: 2.103 ± 0.024	4.928ValPro: 4.928 ± 0.038	2.427ValGln: 2.427 ± 0.023	6.485ValArg: 6.485 ± 0.049	4.96ValSer: 4.96 ± 0.04	5.869ValThr: 5.869 ± 0.048	8.45ValVal: 8.45 ± 0.062	1.144ValTrp: 1.144 ± 0.016	1.593ValTyr: 1.593 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.612TrpAla: 1.612 ± 0.023	0.164TrpCys: 0.164 ± 0.007	0.858TrpAsp: 0.858 ± 0.016	0.688TrpGlu: 0.688 ± 0.015	0.571TrpPhe: 0.571 ± 0.013	1.08TrpGly: 1.08 ± 0.02	0.422TrpHis: 0.422 ± 0.009	0.676TrpIle: 0.676 ± 0.014	0.334TrpLys: 0.334 ± 0.01	1.923TrpLeu: 1.923 ± 0.027	0.34TrpMet: 0.34 ± 0.011	0.489TrpAsn: 0.489 ± 0.013	0.88TrpPro: 0.88 ± 0.015	0.729TrpGln: 0.729 ± 0.015	1.378TrpArg: 1.378 ± 0.02	1.002TrpSer: 1.002 ± 0.015	1.084TrpThr: 1.084 ± 0.018	1.091TrpVal: 1.091 ± 0.017	0.366TrpTrp: 0.366 ± 0.01	0.359TrpTyr: 0.359 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.408TyrAla: 2.408 ± 0.025	0.19TyrCys: 0.19 ± 0.007	1.398TyrAsp: 1.398 ± 0.024	1.12TyrGlu: 1.12 ± 0.018	0.761TyrPhe: 0.761 ± 0.015	2.014TyrGly: 2.014 ± 0.028	0.455TyrHis: 0.455 ± 0.012	0.64TyrIle: 0.64 ± 0.014	0.426TyrLys: 0.426 ± 0.011	2.241TyrLeu: 2.241 ± 0.026	0.32TyrMet: 0.32 ± 0.009	0.54TyrAsn: 0.54 ± 0.015	1.183TyrPro: 1.183 ± 0.018	0.834TyrGln: 0.834 ± 0.016	1.88TyrArg: 1.88 ± 0.023	1.175TyrSer: 1.175 ± 0.019	1.299TyrThr: 1.299 ± 0.021	1.778TyrVal: 1.778 ± 0.024	0.416TyrTrp: 0.416 ± 0.012	0.548TyrTyr: 0.548 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 11140 proteins (3722341 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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