Amino acid dipepetide frequency for Stenotrophomonas phage vB_SmaS_DLP_5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.651AlaAla: 9.651 ± 1.885
0.785AlaCys: 0.785 ± 0.193
4.744AlaAsp: 4.744 ± 0.53
7.164AlaGlu: 7.164 ± 0.609
2.715AlaPhe: 2.715 ± 0.322
5.823AlaGly: 5.823 ± 0.514
1.505AlaHis: 1.505 ± 0.219
4.645AlaIle: 4.645 ± 0.349
6.837AlaLys: 6.837 ± 0.644
6.935AlaLeu: 6.935 ± 0.565
3.762AlaMet: 3.762 ± 0.364
3.108AlaAsn: 3.108 ± 0.437
3.402AlaPro: 3.402 ± 0.339
3.795AlaGln: 3.795 ± 0.532
4.057AlaArg: 4.057 ± 0.36
4.416AlaSer: 4.416 ± 0.624
4.58AlaThr: 4.58 ± 0.597
7.033AlaVal: 7.033 ± 0.415
1.178AlaTrp: 1.178 ± 0.191
2.813AlaTyr: 2.813 ± 0.302
0.0AlaXaa: 0.0 ± 0.0
Cys
0.491CysAla: 0.491 ± 0.115
0.131CysCys: 0.131 ± 0.065
0.687CysAsp: 0.687 ± 0.151
0.916CysGlu: 0.916 ± 0.187
0.425CysPhe: 0.425 ± 0.106
0.883CysGly: 0.883 ± 0.186
0.262CysHis: 0.262 ± 0.082
0.523CysIle: 0.523 ± 0.168
0.654CysLys: 0.654 ± 0.167
0.949CysLeu: 0.949 ± 0.211
0.327CysMet: 0.327 ± 0.105
0.491CysAsn: 0.491 ± 0.128
0.622CysPro: 0.622 ± 0.182
0.327CysGln: 0.327 ± 0.111
0.458CysArg: 0.458 ± 0.123
0.622CysSer: 0.622 ± 0.144
0.654CysThr: 0.654 ± 0.121
0.785CysVal: 0.785 ± 0.139
0.196CysTrp: 0.196 ± 0.074
0.229CysTyr: 0.229 ± 0.079
0.0CysXaa: 0.0 ± 0.0
Asp
4.842AspAla: 4.842 ± 0.501
0.687AspCys: 0.687 ± 0.154
3.141AspAsp: 3.141 ± 0.301
3.828AspGlu: 3.828 ± 0.304
2.225AspPhe: 2.225 ± 0.244
4.58AspGly: 4.58 ± 0.412
1.21AspHis: 1.21 ± 0.201
1.767AspIle: 1.767 ± 0.245
3.337AspLys: 3.337 ± 0.317
5.332AspLeu: 5.332 ± 0.393
2.028AspMet: 2.028 ± 0.304
2.192AspAsn: 2.192 ± 0.29
3.599AspPro: 3.599 ± 0.385
2.454AspGln: 2.454 ± 0.279
2.257AspArg: 2.257 ± 0.26
3.173AspSer: 3.173 ± 0.25
3.37AspThr: 3.37 ± 0.372
4.22AspVal: 4.22 ± 0.317
0.622AspTrp: 0.622 ± 0.14
2.061AspTyr: 2.061 ± 0.241
0.0AspXaa: 0.0 ± 0.0
Glu
7.001GluAla: 7.001 ± 0.617
0.327GluCys: 0.327 ± 0.118
3.762GluAsp: 3.762 ± 0.322
5.594GluGlu: 5.594 ± 0.522
3.958GluPhe: 3.958 ± 0.334
5.79GluGly: 5.79 ± 0.482
1.178GluHis: 1.178 ± 0.207
2.944GluIle: 2.944 ± 0.3
4.416GluLys: 4.416 ± 0.384
6.739GluLeu: 6.739 ± 0.504
2.29GluMet: 2.29 ± 0.295
2.65GluAsn: 2.65 ± 0.272
2.126GluPro: 2.126 ± 0.265
3.86GluGln: 3.86 ± 0.352
3.271GluArg: 3.271 ± 0.323
3.697GluSer: 3.697 ± 0.388
2.879GluThr: 2.879 ± 0.265
5.234GluVal: 5.234 ± 0.459
0.851GluTrp: 0.851 ± 0.162
1.832GluTyr: 1.832 ± 0.261
0.0GluXaa: 0.0 ± 0.0
Phe
2.813PheAla: 2.813 ± 0.329
0.752PheCys: 0.752 ± 0.157
3.01PheAsp: 3.01 ± 0.353
2.421PheGlu: 2.421 ± 0.288
1.309PhePhe: 1.309 ± 0.221
2.912PheGly: 2.912 ± 0.377
0.622PheHis: 0.622 ± 0.141
1.374PheIle: 1.374 ± 0.235
2.584PheLys: 2.584 ± 0.285
2.421PheLeu: 2.421 ± 0.303
1.014PheMet: 1.014 ± 0.182
1.374PheAsn: 1.374 ± 0.201
1.407PhePro: 1.407 ± 0.193
1.734PheGln: 1.734 ± 0.263
1.897PheArg: 1.897 ± 0.28
2.257PheSer: 2.257 ± 0.297
1.996PheThr: 1.996 ± 0.22
3.173PheVal: 3.173 ± 0.373
0.491PheTrp: 0.491 ± 0.125
1.243PheTyr: 1.243 ± 0.227
0.0PheXaa: 0.0 ± 0.0
Gly
5.3GlyAla: 5.3 ± 0.408
1.21GlyCys: 1.21 ± 0.221
4.318GlyAsp: 4.318 ± 0.412
5.234GlyGlu: 5.234 ± 0.393
3.435GlyPhe: 3.435 ± 0.32
6.706GlyGly: 6.706 ± 0.7
1.734GlyHis: 1.734 ± 0.285
3.304GlyIle: 3.304 ± 0.313
5.365GlyLys: 5.365 ± 0.5
6.543GlyLeu: 6.543 ± 0.464
2.519GlyMet: 2.519 ± 0.284
3.37GlyAsn: 3.37 ± 0.417
2.781GlyPro: 2.781 ± 0.336
3.075GlyGln: 3.075 ± 0.277
3.86GlyArg: 3.86 ± 0.351
4.613GlySer: 4.613 ± 0.492
4.384GlyThr: 4.384 ± 0.321
5.627GlyVal: 5.627 ± 0.398
1.374GlyTrp: 1.374 ± 0.203
2.519GlyTyr: 2.519 ± 0.309
0.0GlyXaa: 0.0 ± 0.0
His
1.636HisAla: 1.636 ± 0.246
0.229HisCys: 0.229 ± 0.098
1.014HisAsp: 1.014 ± 0.18
1.243HisGlu: 1.243 ± 0.204
0.851HisPhe: 0.851 ± 0.156
1.309HisGly: 1.309 ± 0.215
0.491HisHis: 0.491 ± 0.133
0.883HisIle: 0.883 ± 0.167
1.178HisLys: 1.178 ± 0.259
1.603HisLeu: 1.603 ± 0.263
0.622HisMet: 0.622 ± 0.143
0.523HisAsn: 0.523 ± 0.117
1.439HisPro: 1.439 ± 0.267
0.72HisGln: 0.72 ± 0.17
1.08HisArg: 1.08 ± 0.234
1.112HisSer: 1.112 ± 0.197
1.243HisThr: 1.243 ± 0.248
1.439HisVal: 1.439 ± 0.234
0.262HisTrp: 0.262 ± 0.091
0.491HisTyr: 0.491 ± 0.126
0.0HisXaa: 0.0 ± 0.0
Ile
4.384IleAla: 4.384 ± 0.402
0.622IleCys: 0.622 ± 0.155
3.697IleAsp: 3.697 ± 0.381
3.599IleGlu: 3.599 ± 0.369
1.112IlePhe: 1.112 ± 0.154
3.631IleGly: 3.631 ± 0.39
1.08IleHis: 1.08 ± 0.186
1.963IleIle: 1.963 ± 0.342
3.108IleLys: 3.108 ± 0.309
3.533IleLeu: 3.533 ± 0.319
0.687IleMet: 0.687 ± 0.147
1.832IleAsn: 1.832 ± 0.245
2.192IlePro: 2.192 ± 0.26
2.192IleGln: 2.192 ± 0.279
2.683IleArg: 2.683 ± 0.278
2.257IleSer: 2.257 ± 0.316
2.846IleThr: 2.846 ± 0.291
3.566IleVal: 3.566 ± 0.36
0.654IleTrp: 0.654 ± 0.15
0.981IleTyr: 0.981 ± 0.189
0.0IleXaa: 0.0 ± 0.0
Lys
7.753LysAla: 7.753 ± 0.702
0.654LysCys: 0.654 ± 0.151
3.828LysAsp: 3.828 ± 0.37
5.169LysGlu: 5.169 ± 0.421
2.355LysPhe: 2.355 ± 0.304
4.613LysGly: 4.613 ± 0.44
1.112LysHis: 1.112 ± 0.204
3.108LysIle: 3.108 ± 0.336
5.987LysLys: 5.987 ± 0.564
5.889LysLeu: 5.889 ± 0.437
2.519LysMet: 2.519 ± 0.274
2.257LysAsn: 2.257 ± 0.244
2.944LysPro: 2.944 ± 0.395
2.061LysGln: 2.061 ± 0.273
2.519LysArg: 2.519 ± 0.29
4.122LysSer: 4.122 ± 0.417
3.893LysThr: 3.893 ± 0.362
5.136LysVal: 5.136 ± 0.51
0.785LysTrp: 0.785 ± 0.159
2.388LysTyr: 2.388 ± 0.256
0.0LysXaa: 0.0 ± 0.0
Leu
7.328LeuAla: 7.328 ± 0.58
0.818LeuCys: 0.818 ± 0.186
4.613LeuAsp: 4.613 ± 0.342
5.594LeuGlu: 5.594 ± 0.39
3.173LeuPhe: 3.173 ± 0.33
5.823LeuGly: 5.823 ± 0.347
1.767LeuHis: 1.767 ± 0.237
4.744LeuIle: 4.744 ± 0.447
5.431LeuLys: 5.431 ± 0.481
6.576LeuLeu: 6.576 ± 0.532
2.65LeuMet: 2.65 ± 0.285
3.337LeuAsn: 3.337 ± 0.304
3.958LeuPro: 3.958 ± 0.358
3.141LeuGln: 3.141 ± 0.408
4.351LeuArg: 4.351 ± 0.354
5.463LeuSer: 5.463 ± 0.514
5.496LeuThr: 5.496 ± 0.384
5.627LeuVal: 5.627 ± 0.441
1.014LeuTrp: 1.014 ± 0.163
2.323LeuTyr: 2.323 ± 0.344
0.0LeuXaa: 0.0 ± 0.0
Met
3.337MetAla: 3.337 ± 0.298
0.294MetCys: 0.294 ± 0.086
1.341MetAsp: 1.341 ± 0.227
1.897MetGlu: 1.897 ± 0.27
1.276MetPhe: 1.276 ± 0.223
2.126MetGly: 2.126 ± 0.308
0.294MetHis: 0.294 ± 0.118
1.93MetIle: 1.93 ± 0.254
2.748MetLys: 2.748 ± 0.355
2.519MetLeu: 2.519 ± 0.325
1.243MetMet: 1.243 ± 0.18
1.439MetAsn: 1.439 ± 0.206
1.309MetPro: 1.309 ± 0.206
1.341MetGln: 1.341 ± 0.183
1.374MetArg: 1.374 ± 0.27
2.29MetSer: 2.29 ± 0.288
1.963MetThr: 1.963 ± 0.313
2.388MetVal: 2.388 ± 0.341
0.556MetTrp: 0.556 ± 0.157
1.341MetTyr: 1.341 ± 0.219
0.0MetXaa: 0.0 ± 0.0
Asn
3.042AsnAla: 3.042 ± 0.494
0.36AsnCys: 0.36 ± 0.103
1.963AsnAsp: 1.963 ± 0.213
2.323AsnGlu: 2.323 ± 0.222
1.112AsnPhe: 1.112 ± 0.192
3.795AsnGly: 3.795 ± 0.388
0.687AsnHis: 0.687 ± 0.156
1.374AsnIle: 1.374 ± 0.222
2.094AsnLys: 2.094 ± 0.285
3.664AsnLeu: 3.664 ± 0.428
1.21AsnMet: 1.21 ± 0.221
1.472AsnAsn: 1.472 ± 0.286
2.454AsnPro: 2.454 ± 0.235
1.668AsnGln: 1.668 ± 0.25
2.126AsnArg: 2.126 ± 0.252
1.996AsnSer: 1.996 ± 0.281
2.225AsnThr: 2.225 ± 0.277
3.206AsnVal: 3.206 ± 0.31
1.21AsnTrp: 1.21 ± 0.153
1.112AsnTyr: 1.112 ± 0.202
0.0AsnXaa: 0.0 ± 0.0
Pro
3.86ProAla: 3.86 ± 0.349
0.72ProCys: 0.72 ± 0.162
2.454ProAsp: 2.454 ± 0.242
3.926ProGlu: 3.926 ± 0.36
1.309ProPhe: 1.309 ± 0.253
2.912ProGly: 2.912 ± 0.305
1.21ProHis: 1.21 ± 0.176
1.57ProIle: 1.57 ± 0.228
3.958ProLys: 3.958 ± 0.4
3.075ProLeu: 3.075 ± 0.416
1.767ProMet: 1.767 ± 0.223
1.93ProAsn: 1.93 ± 0.264
2.126ProPro: 2.126 ± 0.355
1.309ProGln: 1.309 ± 0.218
1.636ProArg: 1.636 ± 0.188
2.355ProSer: 2.355 ± 0.294
2.683ProThr: 2.683 ± 0.325
3.5ProVal: 3.5 ± 0.354
0.556ProTrp: 0.556 ± 0.153
1.538ProTyr: 1.538 ± 0.215
0.0ProXaa: 0.0 ± 0.0
Gln
3.664GlnAla: 3.664 ± 0.579
0.262GlnCys: 0.262 ± 0.078
1.505GlnAsp: 1.505 ± 0.203
2.257GlnGlu: 2.257 ± 0.279
1.701GlnPhe: 1.701 ± 0.174
2.715GlnGly: 2.715 ± 0.286
0.752GlnHis: 0.752 ± 0.18
2.094GlnIle: 2.094 ± 0.318
3.304GlnLys: 3.304 ± 0.344
4.155GlnLeu: 4.155 ± 0.412
1.668GlnMet: 1.668 ± 0.25
1.538GlnAsn: 1.538 ± 0.271
1.505GlnPro: 1.505 ± 0.205
2.094GlnGln: 2.094 ± 0.518
1.897GlnArg: 1.897 ± 0.282
2.617GlnSer: 2.617 ± 0.317
2.355GlnThr: 2.355 ± 0.333
2.977GlnVal: 2.977 ± 0.332
0.393GlnTrp: 0.393 ± 0.113
1.603GlnTyr: 1.603 ± 0.19
0.0GlnXaa: 0.0 ± 0.0
Arg
3.566ArgAla: 3.566 ± 0.367
0.393ArgCys: 0.393 ± 0.115
2.846ArgAsp: 2.846 ± 0.257
3.435ArgGlu: 3.435 ± 0.401
1.963ArgPhe: 1.963 ± 0.296
2.552ArgGly: 2.552 ± 0.283
1.178ArgHis: 1.178 ± 0.205
2.912ArgIle: 2.912 ± 0.322
3.599ArgLys: 3.599 ± 0.349
4.22ArgLeu: 4.22 ± 0.368
1.505ArgMet: 1.505 ± 0.255
1.767ArgAsn: 1.767 ± 0.256
1.668ArgPro: 1.668 ± 0.236
2.421ArgGln: 2.421 ± 0.263
2.944ArgArg: 2.944 ± 0.455
2.454ArgSer: 2.454 ± 0.315
2.388ArgThr: 2.388 ± 0.248
3.762ArgVal: 3.762 ± 0.359
0.916ArgTrp: 0.916 ± 0.191
1.374ArgTyr: 1.374 ± 0.204
0.0ArgXaa: 0.0 ± 0.0
Ser
4.711SerAla: 4.711 ± 0.501
0.589SerCys: 0.589 ± 0.126
3.468SerAsp: 3.468 ± 0.373
3.206SerGlu: 3.206 ± 0.302
2.355SerPhe: 2.355 ± 0.258
5.496SerGly: 5.496 ± 0.481
0.981SerHis: 0.981 ± 0.201
2.912SerIle: 2.912 ± 0.298
3.435SerLys: 3.435 ± 0.407
4.482SerLeu: 4.482 ± 0.34
1.701SerMet: 1.701 ± 0.283
2.584SerAsn: 2.584 ± 0.337
2.552SerPro: 2.552 ± 0.309
2.421SerGln: 2.421 ± 0.273
2.29SerArg: 2.29 ± 0.283
2.846SerSer: 2.846 ± 0.465
3.631SerThr: 3.631 ± 0.394
3.729SerVal: 3.729 ± 0.429
0.687SerTrp: 0.687 ± 0.152
1.505SerTyr: 1.505 ± 0.243
0.0SerXaa: 0.0 ± 0.0
Thr
5.103ThrAla: 5.103 ± 0.52
0.425ThrCys: 0.425 ± 0.119
3.042ThrAsp: 3.042 ± 0.303
4.024ThrGlu: 4.024 ± 0.402
1.701ThrPhe: 1.701 ± 0.214
5.431ThrGly: 5.431 ± 0.444
1.145ThrHis: 1.145 ± 0.206
2.944ThrIle: 2.944 ± 0.308
3.599ThrLys: 3.599 ± 0.337
5.332ThrLeu: 5.332 ± 0.429
1.309ThrMet: 1.309 ± 0.207
2.65ThrAsn: 2.65 ± 0.249
3.042ThrPro: 3.042 ± 0.342
1.603ThrGln: 1.603 ± 0.226
2.028ThrArg: 2.028 ± 0.262
2.944ThrSer: 2.944 ± 0.378
4.089ThrThr: 4.089 ± 0.471
4.482ThrVal: 4.482 ± 0.433
1.014ThrTrp: 1.014 ± 0.181
2.028ThrTyr: 2.028 ± 0.25
0.0ThrXaa: 0.0 ± 0.0
Val
7.001ValAla: 7.001 ± 0.523
0.916ValCys: 0.916 ± 0.223
4.253ValAsp: 4.253 ± 0.365
5.758ValGlu: 5.758 ± 0.469
2.355ValPhe: 2.355 ± 0.255
5.79ValGly: 5.79 ± 0.455
1.112ValHis: 1.112 ± 0.204
3.697ValIle: 3.697 ± 0.379
5.136ValLys: 5.136 ± 0.464
5.463ValLeu: 5.463 ± 0.488
2.65ValMet: 2.65 ± 0.298
2.486ValAsn: 2.486 ± 0.273
3.042ValPro: 3.042 ± 0.326
3.075ValGln: 3.075 ± 0.336
4.384ValArg: 4.384 ± 0.331
4.351ValSer: 4.351 ± 0.463
4.842ValThr: 4.842 ± 0.442
6.445ValVal: 6.445 ± 0.588
0.916ValTrp: 0.916 ± 0.177
2.192ValTyr: 2.192 ± 0.31
0.0ValXaa: 0.0 ± 0.0
Trp
1.112TrpAla: 1.112 ± 0.191
0.131TrpCys: 0.131 ± 0.067
0.523TrpAsp: 0.523 ± 0.133
0.883TrpGlu: 0.883 ± 0.188
0.687TrpPhe: 0.687 ± 0.171
1.047TrpGly: 1.047 ± 0.195
0.491TrpHis: 0.491 ± 0.117
0.622TrpIle: 0.622 ± 0.149
0.556TrpLys: 0.556 ± 0.136
1.439TrpLeu: 1.439 ± 0.233
0.458TrpMet: 0.458 ± 0.138
0.916TrpAsn: 0.916 ± 0.207
0.523TrpPro: 0.523 ± 0.13
0.654TrpGln: 0.654 ± 0.149
0.785TrpArg: 0.785 ± 0.172
0.458TrpSer: 0.458 ± 0.116
0.949TrpThr: 0.949 ± 0.181
1.439TrpVal: 1.439 ± 0.203
0.491TrpTrp: 0.491 ± 0.126
0.556TrpTyr: 0.556 ± 0.112
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.355TyrAla: 2.355 ± 0.266
0.327TyrCys: 0.327 ± 0.103
2.715TyrAsp: 2.715 ± 0.316
1.93TyrGlu: 1.93 ± 0.278
0.785TyrPhe: 0.785 ± 0.134
3.337TyrGly: 3.337 ± 0.391
0.556TyrHis: 0.556 ± 0.145
1.309TyrIle: 1.309 ± 0.197
1.767TyrLys: 1.767 ± 0.267
2.355TyrLeu: 2.355 ± 0.274
1.047TyrMet: 1.047 ± 0.156
1.178TyrAsn: 1.178 ± 0.19
1.701TyrPro: 1.701 ± 0.287
1.112TyrGln: 1.112 ± 0.206
1.996TyrArg: 1.996 ± 0.254
1.538TyrSer: 1.538 ± 0.218
1.472TyrThr: 1.472 ± 0.198
2.094TyrVal: 2.094 ± 0.287
0.556TyrTrp: 0.556 ± 0.154
1.08TyrTyr: 1.08 ± 0.251
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 149 proteins (30569 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski