Amino acid dipepetide frequency for Aedes pseudoscutellaris reovirus (isolate France) (ApRV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.946AlaAla: 1.946 ± 0.493
0.695AlaCys: 0.695 ± 0.342
1.807AlaAsp: 1.807 ± 0.388
1.807AlaGlu: 1.807 ± 0.501
2.085AlaPhe: 2.085 ± 0.309
1.529AlaGly: 1.529 ± 0.453
1.251AlaHis: 1.251 ± 0.389
5.283AlaIle: 5.283 ± 0.848
3.059AlaLys: 3.059 ± 0.45
5.561AlaLeu: 5.561 ± 0.741
1.112AlaMet: 1.112 ± 0.289
4.31AlaAsn: 4.31 ± 1.132
1.39AlaPro: 1.39 ± 0.175
1.251AlaGln: 1.251 ± 0.337
2.363AlaArg: 2.363 ± 0.534
3.476AlaSer: 3.476 ± 0.749
2.502AlaThr: 2.502 ± 0.398
3.198AlaVal: 3.198 ± 0.672
0.417AlaTrp: 0.417 ± 0.26
1.946AlaTyr: 1.946 ± 0.336
0.0AlaXaa: 0.0 ± 0.0
Cys
0.695CysAla: 0.695 ± 0.407
0.0CysCys: 0.0 ± 0.0
1.529CysAsp: 1.529 ± 0.337
0.834CysGlu: 0.834 ± 0.374
0.556CysPhe: 0.556 ± 0.279
0.834CysGly: 0.834 ± 0.387
0.417CysHis: 0.417 ± 0.271
0.556CysIle: 0.556 ± 0.376
0.0CysLys: 0.0 ± 0.0
1.39CysLeu: 1.39 ± 0.292
0.695CysMet: 0.695 ± 0.357
0.834CysAsn: 0.834 ± 0.276
0.278CysPro: 0.278 ± 0.215
0.834CysGln: 0.834 ± 0.33
0.278CysArg: 0.278 ± 0.264
0.556CysSer: 0.556 ± 0.156
0.695CysThr: 0.695 ± 0.285
0.834CysVal: 0.834 ± 0.508
0.139CysTrp: 0.139 ± 0.126
0.556CysTyr: 0.556 ± 0.286
0.0CysXaa: 0.0 ± 0.0
Asp
3.059AspAla: 3.059 ± 0.53
0.417AspCys: 0.417 ± 0.297
4.171AspAsp: 4.171 ± 0.554
3.615AspGlu: 3.615 ± 0.557
2.78AspPhe: 2.78 ± 0.586
2.363AspGly: 2.363 ± 0.558
0.834AspHis: 0.834 ± 0.513
5.283AspIle: 5.283 ± 0.975
2.78AspLys: 2.78 ± 0.408
4.588AspLeu: 4.588 ± 0.572
1.946AspMet: 1.946 ± 0.34
4.588AspAsn: 4.588 ± 1.186
1.112AspPro: 1.112 ± 0.336
1.529AspGln: 1.529 ± 0.366
2.363AspArg: 2.363 ± 0.704
4.727AspSer: 4.727 ± 0.947
4.866AspThr: 4.866 ± 1.112
6.395AspVal: 6.395 ± 0.467
0.278AspTrp: 0.278 ± 0.164
2.085AspTyr: 2.085 ± 0.466
0.0AspXaa: 0.0 ± 0.0
Glu
2.92GluAla: 2.92 ± 0.346
0.417GluCys: 0.417 ± 0.271
4.31GluAsp: 4.31 ± 0.504
1.946GluGlu: 1.946 ± 0.569
3.893GluPhe: 3.893 ± 0.583
1.251GluGly: 1.251 ± 0.221
1.668GluHis: 1.668 ± 0.359
5.283GluIle: 5.283 ± 0.765
2.502GluLys: 2.502 ± 0.498
4.449GluLeu: 4.449 ± 0.521
1.946GluMet: 1.946 ± 0.415
3.337GluAsn: 3.337 ± 0.634
1.807GluPro: 1.807 ± 0.717
3.476GluGln: 3.476 ± 1.048
2.363GluArg: 2.363 ± 0.52
3.476GluSer: 3.476 ± 0.347
3.059GluThr: 3.059 ± 0.491
2.224GluVal: 2.224 ± 0.39
0.417GluTrp: 0.417 ± 0.325
4.449GluTyr: 4.449 ± 0.773
0.0GluXaa: 0.0 ± 0.0
Phe
2.224PheAla: 2.224 ± 0.796
0.695PheCys: 0.695 ± 0.402
3.198PheAsp: 3.198 ± 0.431
2.502PheGlu: 2.502 ± 0.397
1.946PhePhe: 1.946 ± 0.488
1.807PheGly: 1.807 ± 0.52
1.251PheHis: 1.251 ± 0.555
3.476PheIle: 3.476 ± 1.153
4.449PheLys: 4.449 ± 1.029
3.198PheLeu: 3.198 ± 0.761
1.251PheMet: 1.251 ± 0.354
3.476PheAsn: 3.476 ± 0.934
1.251PhePro: 1.251 ± 0.452
1.946PheGln: 1.946 ± 0.615
2.363PheArg: 2.363 ± 0.642
4.31PheSer: 4.31 ± 0.477
3.059PheThr: 3.059 ± 0.496
2.641PheVal: 2.641 ± 0.427
0.139PheTrp: 0.139 ± 0.194
1.946PheTyr: 1.946 ± 0.586
0.0PheXaa: 0.0 ± 0.0
Gly
1.251GlyAla: 1.251 ± 0.218
0.278GlyCys: 0.278 ± 0.155
2.92GlyAsp: 2.92 ± 0.483
1.529GlyGlu: 1.529 ± 0.358
1.39GlyPhe: 1.39 ± 0.269
1.529GlyGly: 1.529 ± 0.25
0.973GlyHis: 0.973 ± 0.357
4.866GlyIle: 4.866 ± 0.838
3.198GlyLys: 3.198 ± 0.554
3.198GlyLeu: 3.198 ± 0.341
1.39GlyMet: 1.39 ± 0.336
2.78GlyAsn: 2.78 ± 0.57
0.417GlyPro: 0.417 ± 0.18
1.529GlyGln: 1.529 ± 0.337
1.807GlyArg: 1.807 ± 0.449
3.337GlySer: 3.337 ± 0.607
2.224GlyThr: 2.224 ± 0.527
2.78GlyVal: 2.78 ± 0.312
0.0GlyTrp: 0.0 ± 0.0
1.807GlyTyr: 1.807 ± 0.308
0.0GlyXaa: 0.0 ± 0.0
His
1.529HisAla: 1.529 ± 0.471
0.139HisCys: 0.139 ± 0.126
0.834HisAsp: 0.834 ± 0.28
0.834HisGlu: 0.834 ± 0.304
0.556HisPhe: 0.556 ± 0.22
1.668HisGly: 1.668 ± 0.32
0.417HisHis: 0.417 ± 0.187
2.224HisIle: 2.224 ± 0.608
1.251HisLys: 1.251 ± 0.374
2.085HisLeu: 2.085 ± 0.48
0.834HisMet: 0.834 ± 0.325
1.946HisAsn: 1.946 ± 0.771
0.556HisPro: 0.556 ± 0.18
0.973HisGln: 0.973 ± 0.286
1.112HisArg: 1.112 ± 0.48
1.668HisSer: 1.668 ± 0.396
1.946HisThr: 1.946 ± 0.542
2.085HisVal: 2.085 ± 0.358
0.0HisTrp: 0.0 ± 0.0
0.278HisTyr: 0.278 ± 0.213
0.0HisXaa: 0.0 ± 0.0
Ile
3.893IleAla: 3.893 ± 0.743
1.807IleCys: 1.807 ± 0.327
6.812IleAsp: 6.812 ± 0.981
6.534IleGlu: 6.534 ± 0.831
2.92IlePhe: 2.92 ± 0.444
3.059IleGly: 3.059 ± 0.663
1.529IleHis: 1.529 ± 0.401
6.117IleIle: 6.117 ± 0.828
3.893IleLys: 3.893 ± 0.362
8.341IleLeu: 8.341 ± 1.228
1.946IleMet: 1.946 ± 0.506
7.368IleAsn: 7.368 ± 0.621
4.449IlePro: 4.449 ± 0.612
5.144IleGln: 5.144 ± 0.859
4.449IleArg: 4.449 ± 0.453
9.732IleSer: 9.732 ± 1.262
5.422IleThr: 5.422 ± 0.845
4.727IleVal: 4.727 ± 0.519
0.834IleTrp: 0.834 ± 0.333
1.668IleTyr: 1.668 ± 0.38
0.0IleXaa: 0.0 ± 0.0
Lys
2.363LysAla: 2.363 ± 0.348
0.556LysCys: 0.556 ± 0.194
2.78LysAsp: 2.78 ± 0.725
2.363LysGlu: 2.363 ± 0.946
3.615LysPhe: 3.615 ± 0.853
1.529LysGly: 1.529 ± 0.397
2.085LysHis: 2.085 ± 0.424
5.561LysIle: 5.561 ± 0.811
2.502LysLys: 2.502 ± 0.5
6.673LysLeu: 6.673 ± 1.465
1.529LysMet: 1.529 ± 0.289
3.059LysAsn: 3.059 ± 0.629
2.78LysPro: 2.78 ± 0.498
2.363LysGln: 2.363 ± 0.413
2.502LysArg: 2.502 ± 0.366
3.476LysSer: 3.476 ± 0.395
3.754LysThr: 3.754 ± 0.532
3.059LysVal: 3.059 ± 0.804
0.834LysTrp: 0.834 ± 0.28
3.615LysTyr: 3.615 ± 0.841
0.0LysXaa: 0.0 ± 0.0
Leu
3.476LeuAla: 3.476 ± 0.44
1.946LeuCys: 1.946 ± 0.831
3.615LeuAsp: 3.615 ± 0.374
4.866LeuGlu: 4.866 ± 0.524
4.032LeuPhe: 4.032 ± 0.513
2.92LeuGly: 2.92 ± 0.405
1.946LeuHis: 1.946 ± 0.314
9.037LeuIle: 9.037 ± 0.7
5.283LeuLys: 5.283 ± 0.406
8.619LeuLeu: 8.619 ± 1.075
1.807LeuMet: 1.807 ± 0.365
6.951LeuAsn: 6.951 ± 0.787
4.171LeuPro: 4.171 ± 0.843
4.866LeuGln: 4.866 ± 1.036
5.144LeuArg: 5.144 ± 1.051
7.229LeuSer: 7.229 ± 0.785
6.256LeuThr: 6.256 ± 0.912
4.032LeuVal: 4.032 ± 0.723
0.417LeuTrp: 0.417 ± 0.173
5.978LeuTyr: 5.978 ± 0.753
0.0LeuXaa: 0.0 ± 0.0
Met
0.973MetAla: 0.973 ± 0.423
0.139MetCys: 0.139 ± 0.126
2.224MetAsp: 2.224 ± 0.557
0.973MetGlu: 0.973 ± 0.45
2.502MetPhe: 2.502 ± 0.659
0.556MetGly: 0.556 ± 0.179
0.556MetHis: 0.556 ± 0.253
2.224MetIle: 2.224 ± 0.691
1.946MetLys: 1.946 ± 0.412
3.059MetLeu: 3.059 ± 0.255
0.973MetMet: 0.973 ± 0.377
2.085MetAsn: 2.085 ± 0.276
0.834MetPro: 0.834 ± 0.378
1.251MetGln: 1.251 ± 0.236
1.39MetArg: 1.39 ± 0.273
2.085MetSer: 2.085 ± 0.32
1.251MetThr: 1.251 ± 0.543
1.39MetVal: 1.39 ± 0.349
0.0MetTrp: 0.0 ± 0.0
2.224MetTyr: 2.224 ± 0.569
0.0MetXaa: 0.0 ± 0.0
Asn
5.005AsnAla: 5.005 ± 0.815
0.417AsnCys: 0.417 ± 0.201
4.31AsnAsp: 4.31 ± 0.772
4.171AsnGlu: 4.171 ± 0.877
3.754AsnPhe: 3.754 ± 0.72
3.337AsnGly: 3.337 ± 0.722
1.39AsnHis: 1.39 ± 0.4
7.507AsnIle: 7.507 ± 0.576
2.78AsnLys: 2.78 ± 0.482
5.005AsnLeu: 5.005 ± 0.835
3.059AsnMet: 3.059 ± 0.546
4.31AsnAsn: 4.31 ± 0.595
1.946AsnPro: 1.946 ± 0.421
3.754AsnGln: 3.754 ± 0.516
2.502AsnArg: 2.502 ± 0.681
3.337AsnSer: 3.337 ± 0.523
5.144AsnThr: 5.144 ± 1.009
4.727AsnVal: 4.727 ± 0.812
0.278AsnTrp: 0.278 ± 0.149
2.363AsnTyr: 2.363 ± 0.381
0.0AsnXaa: 0.0 ± 0.0
Pro
1.251ProAla: 1.251 ± 0.301
0.278ProCys: 0.278 ± 0.187
1.807ProAsp: 1.807 ± 0.45
1.668ProGlu: 1.668 ± 0.276
1.946ProPhe: 1.946 ± 0.771
0.973ProGly: 0.973 ± 0.534
0.278ProHis: 0.278 ± 0.159
3.198ProIle: 3.198 ± 0.688
2.085ProLys: 2.085 ± 0.674
3.059ProLeu: 3.059 ± 0.532
1.251ProMet: 1.251 ± 0.625
2.78ProAsn: 2.78 ± 0.634
0.834ProPro: 0.834 ± 0.289
0.834ProGln: 0.834 ± 0.241
1.39ProArg: 1.39 ± 0.456
2.224ProSer: 2.224 ± 0.503
3.337ProThr: 3.337 ± 1.052
1.946ProVal: 1.946 ± 0.66
0.0ProTrp: 0.0 ± 0.0
2.085ProTyr: 2.085 ± 0.385
0.0ProXaa: 0.0 ± 0.0
Gln
2.085GlnAla: 2.085 ± 0.473
0.973GlnCys: 0.973 ± 0.31
2.363GlnAsp: 2.363 ± 0.549
3.059GlnGlu: 3.059 ± 0.816
2.224GlnPhe: 2.224 ± 0.68
1.946GlnGly: 1.946 ± 0.346
1.39GlnHis: 1.39 ± 0.454
4.727GlnIle: 4.727 ± 0.681
2.224GlnLys: 2.224 ± 0.748
5.422GlnLeu: 5.422 ± 0.808
1.251GlnMet: 1.251 ± 0.482
3.893GlnAsn: 3.893 ± 0.478
2.363GlnPro: 2.363 ± 0.573
1.946GlnGln: 1.946 ± 0.541
1.668GlnArg: 1.668 ± 0.476
2.085GlnSer: 2.085 ± 0.636
2.085GlnThr: 2.085 ± 0.35
3.059GlnVal: 3.059 ± 0.581
0.278GlnTrp: 0.278 ± 0.242
2.085GlnTyr: 2.085 ± 0.459
0.0GlnXaa: 0.0 ± 0.0
Arg
3.059ArgAla: 3.059 ± 0.868
0.417ArgCys: 0.417 ± 0.297
2.502ArgAsp: 2.502 ± 0.886
2.92ArgGlu: 2.92 ± 0.32
1.529ArgPhe: 1.529 ± 0.269
2.363ArgGly: 2.363 ± 0.451
0.973ArgHis: 0.973 ± 0.426
3.615ArgIle: 3.615 ± 0.671
3.337ArgLys: 3.337 ± 0.813
4.032ArgLeu: 4.032 ± 0.813
2.224ArgMet: 2.224 ± 0.584
1.251ArgAsn: 1.251 ± 0.525
1.251ArgPro: 1.251 ± 0.356
2.502ArgGln: 2.502 ± 0.657
2.92ArgArg: 2.92 ± 0.762
2.224ArgSer: 2.224 ± 0.441
3.198ArgThr: 3.198 ± 0.716
2.363ArgVal: 2.363 ± 0.646
0.278ArgTrp: 0.278 ± 0.264
2.085ArgTyr: 2.085 ± 0.462
0.0ArgXaa: 0.0 ± 0.0
Ser
2.78SerAla: 2.78 ± 0.631
0.695SerCys: 0.695 ± 0.257
5.7SerAsp: 5.7 ± 0.595
4.449SerGlu: 4.449 ± 0.608
3.893SerPhe: 3.893 ± 0.717
4.032SerGly: 4.032 ± 0.742
1.946SerHis: 1.946 ± 0.367
6.256SerIle: 6.256 ± 0.692
3.754SerLys: 3.754 ± 0.664
7.924SerLeu: 7.924 ± 1.062
1.946SerMet: 1.946 ± 0.361
5.005SerAsn: 5.005 ± 0.618
0.973SerPro: 0.973 ± 0.355
4.032SerGln: 4.032 ± 0.561
2.78SerArg: 2.78 ± 0.335
5.283SerSer: 5.283 ± 1.235
5.561SerThr: 5.561 ± 1.264
4.032SerVal: 4.032 ± 0.553
0.556SerTrp: 0.556 ± 0.284
1.946SerTyr: 1.946 ± 0.416
0.0SerXaa: 0.0 ± 0.0
Thr
3.198ThrAla: 3.198 ± 0.923
0.834ThrCys: 0.834 ± 0.307
2.78ThrAsp: 2.78 ± 0.661
3.615ThrGlu: 3.615 ± 0.541
2.363ThrPhe: 2.363 ± 0.579
3.337ThrGly: 3.337 ± 0.862
1.39ThrHis: 1.39 ± 0.446
5.7ThrIle: 5.7 ± 1.068
3.476ThrLys: 3.476 ± 0.662
5.144ThrLeu: 5.144 ± 0.725
1.112ThrMet: 1.112 ± 0.377
3.615ThrAsn: 3.615 ± 0.562
2.085ThrPro: 2.085 ± 0.555
3.893ThrGln: 3.893 ± 0.703
3.198ThrArg: 3.198 ± 0.439
5.839ThrSer: 5.839 ± 1.181
6.256ThrThr: 6.256 ± 1.154
4.727ThrVal: 4.727 ± 0.792
0.556ThrTrp: 0.556 ± 0.28
4.449ThrTyr: 4.449 ± 0.854
0.0ThrXaa: 0.0 ± 0.0
Val
2.641ValAla: 2.641 ± 0.75
1.807ValCys: 1.807 ± 0.32
2.502ValAsp: 2.502 ± 0.721
3.893ValGlu: 3.893 ± 0.682
2.78ValPhe: 2.78 ± 0.52
1.946ValGly: 1.946 ± 0.384
1.529ValHis: 1.529 ± 0.554
4.727ValIle: 4.727 ± 0.528
5.144ValLys: 5.144 ± 0.554
5.422ValLeu: 5.422 ± 0.884
1.251ValMet: 1.251 ± 0.382
3.476ValAsn: 3.476 ± 0.576
2.363ValPro: 2.363 ± 0.486
3.059ValGln: 3.059 ± 0.602
2.502ValArg: 2.502 ± 0.328
5.422ValSer: 5.422 ± 0.726
3.754ValThr: 3.754 ± 0.766
3.059ValVal: 3.059 ± 0.844
0.556ValTrp: 0.556 ± 0.35
2.224ValTyr: 2.224 ± 0.508
0.0ValXaa: 0.0 ± 0.0
Trp
0.139TrpAla: 0.139 ± 0.194
0.0TrpCys: 0.0 ± 0.0
0.417TrpAsp: 0.417 ± 0.219
0.139TrpGlu: 0.139 ± 0.121
1.112TrpPhe: 1.112 ± 0.318
0.278TrpGly: 0.278 ± 0.149
0.278TrpHis: 0.278 ± 0.162
0.417TrpIle: 0.417 ± 0.197
0.834TrpLys: 0.834 ± 0.543
0.973TrpLeu: 0.973 ± 0.382
0.139TrpMet: 0.139 ± 0.124
0.556TrpAsn: 0.556 ± 0.156
0.417TrpPro: 0.417 ± 0.155
0.0TrpGln: 0.0 ± 0.0
0.417TrpArg: 0.417 ± 0.243
0.139TrpSer: 0.139 ± 0.124
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.139TrpTyr: 0.139 ± 0.131
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.502TyrAla: 2.502 ± 0.669
0.0TyrCys: 0.0 ± 0.0
3.198TyrAsp: 3.198 ± 0.496
3.476TyrGlu: 3.476 ± 0.723
1.251TyrPhe: 1.251 ± 0.405
1.946TyrGly: 1.946 ± 0.298
0.834TyrHis: 0.834 ± 0.269
4.727TyrIle: 4.727 ± 1.147
2.502TyrLys: 2.502 ± 0.443
4.449TyrLeu: 4.449 ± 0.755
0.834TyrMet: 0.834 ± 0.404
3.476TyrAsn: 3.476 ± 0.729
1.946TyrPro: 1.946 ± 0.456
1.946TyrGln: 1.946 ± 0.619
1.529TyrArg: 1.529 ± 0.588
2.92TyrSer: 2.92 ± 0.658
3.198TyrThr: 3.198 ± 0.479
2.78TyrVal: 2.78 ± 1.056
0.417TyrTrp: 0.417 ± 0.388
1.39TyrTyr: 1.39 ± 0.394
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (7194 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski