Amino acid dipepetide frequency for Solimonas terrae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.323AlaAla: 18.323 ± 0.197	1.317AlaCys: 1.317 ± 0.031	7.675AlaAsp: 7.675 ± 0.101	6.678AlaGlu: 6.678 ± 0.088	3.944AlaPhe: 3.944 ± 0.056	10.632AlaGly: 10.632 ± 0.087	2.667AlaHis: 2.667 ± 0.046	5.777AlaIle: 5.777 ± 0.062	3.245AlaLys: 3.245 ± 0.064	13.887AlaLeu: 13.887 ± 0.12	3.097AlaMet: 3.097 ± 0.051	2.83AlaAsn: 2.83 ± 0.055	6.289AlaPro: 6.289 ± 0.09	5.305AlaGln: 5.305 ± 0.08	9.792AlaArg: 9.792 ± 0.115	6.7AlaSer: 6.7 ± 0.081	5.957AlaThr: 5.957 ± 0.075	8.461AlaVal: 8.461 ± 0.088	1.705AlaTrp: 1.705 ± 0.038	2.754AlaTyr: 2.754 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	1.223CysAla: 1.223 ± 0.03	0.134CysCys: 0.134 ± 0.01	0.56CysAsp: 0.56 ± 0.019	0.515CysGlu: 0.515 ± 0.02	0.31CysPhe: 0.31 ± 0.016	1.065CysGly: 1.065 ± 0.034	0.272CysHis: 0.272 ± 0.021	0.399CysIle: 0.399 ± 0.016	0.21CysLys: 0.21 ± 0.012	0.848CysLeu: 0.848 ± 0.025	0.177CysMet: 0.177 ± 0.013	0.235CysAsn: 0.235 ± 0.014	0.503CysPro: 0.503 ± 0.022	0.246CysGln: 0.246 ± 0.013	0.701CysArg: 0.701 ± 0.021	0.537CysSer: 0.537 ± 0.019	0.487CysThr: 0.487 ± 0.021	0.729CysVal: 0.729 ± 0.024	0.138CysTrp: 0.138 ± 0.011	0.236CysTyr: 0.236 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.587AspAla: 8.587 ± 0.099	0.525AspCys: 0.525 ± 0.02	3.828AspAsp: 3.828 ± 0.061	3.498AspGlu: 3.498 ± 0.05	2.268AspPhe: 2.268 ± 0.039	5.838AspGly: 5.838 ± 0.083	1.304AspHis: 1.304 ± 0.035	2.643AspIle: 2.643 ± 0.049	1.713AspLys: 1.713 ± 0.039	5.627AspLeu: 5.627 ± 0.074	1.055AspMet: 1.055 ± 0.027	1.46AspAsn: 1.46 ± 0.038	3.283AspPro: 3.283 ± 0.049	1.734AspGln: 1.734 ± 0.041	3.934AspArg: 3.934 ± 0.058	2.816AspSer: 2.816 ± 0.05	2.741AspThr: 2.741 ± 0.049	4.306AspVal: 4.306 ± 0.054	1.064AspTrp: 1.064 ± 0.031	1.787AspTyr: 1.787 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.364GluAla: 6.364 ± 0.082	0.392GluCys: 0.392 ± 0.017	2.218GluAsp: 2.218 ± 0.043	2.022GluGlu: 2.022 ± 0.055	1.784GluPhe: 1.784 ± 0.036	3.151GluGly: 3.151 ± 0.048	1.488GluHis: 1.488 ± 0.028	2.942GluIle: 2.942 ± 0.054	1.782GluLys: 1.782 ± 0.045	6.289GluLeu: 6.289 ± 0.079	1.16GluMet: 1.16 ± 0.031	1.271GluAsn: 1.271 ± 0.034	2.368GluPro: 2.368 ± 0.039	2.526GluGln: 2.526 ± 0.05	4.626GluArg: 4.626 ± 0.069	2.516GluSer: 2.516 ± 0.045	2.736GluThr: 2.736 ± 0.052	3.476GluVal: 3.476 ± 0.049	0.672GluTrp: 0.672 ± 0.023	1.151GluTyr: 1.151 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.512PheAla: 4.512 ± 0.059	0.409PheCys: 0.409 ± 0.019	2.742PheAsp: 2.742 ± 0.047	2.035PheGlu: 2.035 ± 0.04	1.245PhePhe: 1.245 ± 0.035	3.485PheGly: 3.485 ± 0.055	0.79PheHis: 0.79 ± 0.026	1.476PheIle: 1.476 ± 0.033	0.992PheLys: 0.992 ± 0.029	2.856PheLeu: 2.856 ± 0.051	0.711PheMet: 0.711 ± 0.024	1.055PheAsn: 1.055 ± 0.028	1.423PhePro: 1.423 ± 0.031	0.895PheGln: 0.895 ± 0.027	2.256PheArg: 2.256 ± 0.038	2.069PheSer: 2.069 ± 0.046	1.951PheThr: 1.951 ± 0.043	2.806PheVal: 2.806 ± 0.047	0.487PheTrp: 0.487 ± 0.022	0.952PheTyr: 0.952 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	9.167GlyAla: 9.167 ± 0.101	0.92GlyCys: 0.92 ± 0.029	4.952GlyAsp: 4.952 ± 0.078	4.514GlyGlu: 4.514 ± 0.062	3.362GlyPhe: 3.362 ± 0.053	7.472GlyGly: 7.472 ± 0.112	2.068GlyHis: 2.068 ± 0.04	4.287GlyIle: 4.287 ± 0.064	3.204GlyLys: 3.204 ± 0.058	8.499GlyLeu: 8.499 ± 0.094	1.936GlyMet: 1.936 ± 0.042	2.255GlyAsn: 2.255 ± 0.048	3.09GlyPro: 3.09 ± 0.049	2.722GlyGln: 2.722 ± 0.048	5.688GlyArg: 5.688 ± 0.071	5.061GlySer: 5.061 ± 0.078	4.381GlyThr: 4.381 ± 0.075	6.347GlyVal: 6.347 ± 0.071	1.368GlyTrp: 1.368 ± 0.035	2.559GlyTyr: 2.559 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.873HisAla: 2.873 ± 0.055	0.32HisCys: 0.32 ± 0.016	1.446HisAsp: 1.446 ± 0.034	1.258HisGlu: 1.258 ± 0.031	0.991HisPhe: 0.991 ± 0.027	2.205HisGly: 2.205 ± 0.046	0.669HisHis: 0.669 ± 0.027	0.885HisIle: 0.885 ± 0.021	0.54HisLys: 0.54 ± 0.018	2.401HisLeu: 2.401 ± 0.046	0.439HisMet: 0.439 ± 0.019	0.509HisAsn: 0.509 ± 0.021	1.401HisPro: 1.401 ± 0.029	0.643HisGln: 0.643 ± 0.02	1.717HisArg: 1.717 ± 0.037	1.045HisSer: 1.045 ± 0.031	0.933HisThr: 0.933 ± 0.028	1.622HisVal: 1.622 ± 0.039	0.468HisTrp: 0.468 ± 0.021	0.796HisTyr: 0.796 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.885IleAla: 6.885 ± 0.071	0.448IleCys: 0.448 ± 0.016	3.575IleAsp: 3.575 ± 0.06	3.303IleGlu: 3.303 ± 0.054	1.352IlePhe: 1.352 ± 0.035	4.632IleGly: 4.632 ± 0.063	0.931IleHis: 0.931 ± 0.029	1.674IleIle: 1.674 ± 0.037	1.426IleLys: 1.426 ± 0.039	3.281IleLeu: 3.281 ± 0.055	0.682IleMet: 0.682 ± 0.024	1.421IleAsn: 1.421 ± 0.032	2.095IlePro: 2.095 ± 0.041	1.13IleGln: 1.13 ± 0.03	2.987IleArg: 2.987 ± 0.044	2.513IleSer: 2.513 ± 0.052	2.404IleThr: 2.404 ± 0.052	4.061IleVal: 4.061 ± 0.058	0.569IleTrp: 0.569 ± 0.02	1.08IleTyr: 1.08 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.669LysAla: 3.669 ± 0.064	0.181LysCys: 0.181 ± 0.013	1.537LysAsp: 1.537 ± 0.042	1.144LysGlu: 1.144 ± 0.036	0.859LysPhe: 0.859 ± 0.026	2.19LysGly: 2.19 ± 0.044	0.603LysHis: 0.603 ± 0.021	1.505LysIle: 1.505 ± 0.038	1.18LysLys: 1.18 ± 0.037	3.795LysLeu: 3.795 ± 0.057	0.681LysMet: 0.681 ± 0.022	0.831LysAsn: 0.831 ± 0.027	2.087LysPro: 2.087 ± 0.039	1.153LysGln: 1.153 ± 0.033	2.15LysArg: 2.15 ± 0.045	1.675LysSer: 1.675 ± 0.034	1.825LysThr: 1.825 ± 0.042	2.057LysVal: 2.057 ± 0.046	0.349LysTrp: 0.349 ± 0.018	0.695LysTyr: 0.695 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	13.956LeuAla: 13.956 ± 0.125	1.07LeuCys: 1.07 ± 0.028	6.7LeuAsp: 6.7 ± 0.074	4.865LeuGlu: 4.865 ± 0.07	3.579LeuPhe: 3.579 ± 0.071	8.609LeuGly: 8.609 ± 0.086	2.524LeuHis: 2.524 ± 0.053	4.758LeuIle: 4.758 ± 0.072	3.581LeuLys: 3.581 ± 0.065	11.384LeuLeu: 11.384 ± 0.136	2.263LeuMet: 2.263 ± 0.039	2.632LeuAsn: 2.632 ± 0.042	6.122LeuPro: 6.122 ± 0.067	4.304LeuGln: 4.304 ± 0.06	8.432LeuArg: 8.432 ± 0.1	6.402LeuSer: 6.402 ± 0.069	4.897LeuThr: 4.897 ± 0.072	6.744LeuVal: 6.744 ± 0.075	1.348LeuTrp: 1.348 ± 0.036	2.282LeuTyr: 2.282 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.451MetAla: 2.451 ± 0.035	0.165MetCys: 0.165 ± 0.01	0.95MetAsp: 0.95 ± 0.027	0.834MetGlu: 0.834 ± 0.027	0.768MetPhe: 0.768 ± 0.026	1.388MetGly: 1.388 ± 0.032	0.501MetHis: 0.501 ± 0.015	1.036MetIle: 1.036 ± 0.031	0.994MetLys: 0.994 ± 0.028	2.528MetLeu: 2.528 ± 0.046	0.524MetMet: 0.524 ± 0.023	0.818MetAsn: 0.818 ± 0.025	1.444MetPro: 1.444 ± 0.033	0.979MetGln: 0.979 ± 0.028	1.683MetArg: 1.683 ± 0.039	1.594MetSer: 1.594 ± 0.032	1.395MetThr: 1.395 ± 0.033	1.272MetVal: 1.272 ± 0.029	0.183MetTrp: 0.183 ± 0.011	0.367MetTyr: 0.367 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.182AsnAla: 3.182 ± 0.055	0.258AsnCys: 0.258 ± 0.014	1.491AsnAsp: 1.491 ± 0.038	1.233AsnGlu: 1.233 ± 0.031	1.0AsnPhe: 1.0 ± 0.031	2.409AsnGly: 2.409 ± 0.053	0.497AsnHis: 0.497 ± 0.02	1.205AsnIle: 1.205 ± 0.031	0.714AsnLys: 0.714 ± 0.025	2.679AsnLeu: 2.679 ± 0.048	0.511AsnMet: 0.511 ± 0.021	0.72AsnAsn: 0.72 ± 0.029	1.722AsnPro: 1.722 ± 0.034	0.794AsnGln: 0.794 ± 0.029	1.737AsnArg: 1.737 ± 0.038	1.264AsnSer: 1.264 ± 0.037	1.329AsnThr: 1.329 ± 0.034	1.933AsnVal: 1.933 ± 0.048	0.412AsnTrp: 0.412 ± 0.019	0.777AsnTyr: 0.777 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	6.882ProAla: 6.882 ± 0.088	0.354ProCys: 0.354 ± 0.016	3.669ProAsp: 3.669 ± 0.051	2.962ProGlu: 2.962 ± 0.051	1.785ProPhe: 1.785 ± 0.032	4.481ProGly: 4.481 ± 0.075	1.098ProHis: 1.098 ± 0.032	2.127ProIle: 2.127 ± 0.041	1.554ProLys: 1.554 ± 0.037	5.28ProLeu: 5.28 ± 0.068	1.25ProMet: 1.25 ± 0.03	1.24ProAsn: 1.24 ± 0.03	2.878ProPro: 2.878 ± 0.07	2.232ProGln: 2.232 ± 0.049	3.194ProArg: 3.194 ± 0.051	2.735ProSer: 2.735 ± 0.044	2.492ProThr: 2.492 ± 0.045	3.919ProVal: 3.919 ± 0.059	0.678ProTrp: 0.678 ± 0.023	1.299ProTyr: 1.299 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.871GlnAla: 4.871 ± 0.078	0.295GlnCys: 0.295 ± 0.018	1.588GlnAsp: 1.588 ± 0.032	1.306GlnGlu: 1.306 ± 0.036	1.272GlnPhe: 1.272 ± 0.031	2.498GlnGly: 2.498 ± 0.041	0.9GlnHis: 0.9 ± 0.027	1.983GlnIle: 1.983 ± 0.04	1.086GlnLys: 1.086 ± 0.031	4.478GlnLeu: 4.478 ± 0.066	0.91GlnMet: 0.91 ± 0.026	0.915GlnAsn: 0.915 ± 0.026	1.992GlnPro: 1.992 ± 0.037	1.89GlnGln: 1.89 ± 0.055	3.219GlnArg: 3.219 ± 0.053	1.894GlnSer: 1.894 ± 0.037	2.031GlnThr: 2.031 ± 0.038	2.385GlnVal: 2.385 ± 0.044	0.623GlnTrp: 0.623 ± 0.023	0.98GlnTyr: 0.98 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	8.309ArgAla: 8.309 ± 0.099	0.65ArgCys: 0.65 ± 0.023	4.416ArgAsp: 4.416 ± 0.058	4.348ArgGlu: 4.348 ± 0.064	2.891ArgPhe: 2.891 ± 0.041	5.127ArgGly: 5.127 ± 0.066	2.031ArgHis: 2.031 ± 0.044	3.914ArgIle: 3.914 ± 0.057	2.21ArgLys: 2.21 ± 0.041	8.475ArgLeu: 8.475 ± 0.097	1.743ArgMet: 1.743 ± 0.036	1.877ArgAsn: 1.877 ± 0.037	3.32ArgPro: 3.32 ± 0.06	2.785ArgGln: 2.785 ± 0.051	6.171ArgArg: 6.171 ± 0.09	3.73ArgSer: 3.73 ± 0.053	3.171ArgThr: 3.171 ± 0.049	5.209ArgVal: 5.209 ± 0.061	1.253ArgTrp: 1.253 ± 0.029	2.456ArgTyr: 2.456 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.742SerAla: 6.742 ± 0.073	0.545SerCys: 0.545 ± 0.02	3.089SerAsp: 3.089 ± 0.055	2.578SerGlu: 2.578 ± 0.047	2.158SerPhe: 2.158 ± 0.043	5.653SerGly: 5.653 ± 0.084	1.106SerHis: 1.106 ± 0.028	2.4SerIle: 2.4 ± 0.045	1.518SerLys: 1.518 ± 0.038	5.773SerLeu: 5.773 ± 0.084	1.232SerMet: 1.232 ± 0.032	1.387SerAsn: 1.387 ± 0.039	2.739SerPro: 2.739 ± 0.051	1.745SerGln: 1.745 ± 0.039	3.632SerArg: 3.632 ± 0.052	3.221SerSer: 3.221 ± 0.06	2.833SerThr: 2.833 ± 0.053	3.912SerVal: 3.912 ± 0.059	0.857SerTrp: 0.857 ± 0.027	1.484SerTyr: 1.484 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	6.113ThrAla: 6.113 ± 0.084	0.391ThrCys: 0.391 ± 0.018	2.59ThrAsp: 2.59 ± 0.049	2.202ThrGlu: 2.202 ± 0.044	1.532ThrPhe: 1.532 ± 0.038	4.33ThrGly: 4.33 ± 0.071	1.136ThrHis: 1.136 ± 0.03	2.413ThrIle: 2.413 ± 0.041	1.082ThrLys: 1.082 ± 0.037	6.106ThrLeu: 6.106 ± 0.06	1.156ThrMet: 1.156 ± 0.03	1.112ThrAsn: 1.112 ± 0.035	3.543ThrPro: 3.543 ± 0.059	1.858ThrGln: 1.858 ± 0.036	3.696ThrArg: 3.696 ± 0.053	2.475ThrSer: 2.475 ± 0.053	2.851ThrThr: 2.851 ± 0.071	3.935ThrVal: 3.935 ± 0.065	0.583ThrTrp: 0.583 ± 0.023	1.165ThrTyr: 1.165 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	8.65ValAla: 8.65 ± 0.08	0.71ValCys: 0.71 ± 0.025	4.693ValAsp: 4.693 ± 0.062	3.835ValGlu: 3.835 ± 0.057	2.471ValPhe: 2.471 ± 0.051	5.486ValGly: 5.486 ± 0.067	1.604ValHis: 1.604 ± 0.037	3.448ValIle: 3.448 ± 0.053	1.988ValLys: 1.988 ± 0.046	7.631ValLeu: 7.631 ± 0.082	1.59ValMet: 1.59 ± 0.037	2.073ValAsn: 2.073 ± 0.048	3.825ValPro: 3.825 ± 0.053	2.459ValGln: 2.459 ± 0.052	5.017ValArg: 5.017 ± 0.064	4.054ValSer: 4.054 ± 0.061	3.829ValThr: 3.829 ± 0.059	5.547ValVal: 5.547 ± 0.077	0.915ValTrp: 0.915 ± 0.029	1.602ValTyr: 1.602 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.261TrpAla: 1.261 ± 0.036	0.169TrpCys: 0.169 ± 0.011	0.7TrpAsp: 0.7 ± 0.023	0.482TrpGlu: 0.482 ± 0.02	0.524TrpPhe: 0.524 ± 0.021	0.874TrpGly: 0.874 ± 0.027	0.411TrpHis: 0.411 ± 0.019	0.662TrpIle: 0.662 ± 0.023	0.467TrpLys: 0.467 ± 0.019	2.021TrpLeu: 2.021 ± 0.044	0.35TrpMet: 0.35 ± 0.017	0.523TrpAsn: 0.523 ± 0.023	0.738TrpPro: 0.738 ± 0.024	0.789TrpGln: 0.789 ± 0.031	1.228TrpArg: 1.228 ± 0.031	0.885TrpSer: 0.885 ± 0.026	0.794TrpThr: 0.794 ± 0.026	0.844TrpVal: 0.844 ± 0.025	0.29TrpTrp: 0.29 ± 0.015	0.352TrpTyr: 0.352 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.014TyrAla: 3.014 ± 0.051	0.273TyrCys: 0.273 ± 0.015	1.593TyrAsp: 1.593 ± 0.044	1.321TyrGlu: 1.321 ± 0.035	1.049TyrPhe: 1.049 ± 0.026	2.326TyrGly: 2.326 ± 0.048	0.562TyrHis: 0.562 ± 0.021	0.915TyrIle: 0.915 ± 0.03	0.681TyrLys: 0.681 ± 0.026	2.616TyrLeu: 2.616 ± 0.046	0.406TyrMet: 0.406 ± 0.017	0.704TyrAsn: 0.704 ± 0.025	1.249TyrPro: 1.249 ± 0.034	0.928TyrGln: 0.928 ± 0.028	2.226TyrArg: 2.226 ± 0.042	1.418TyrSer: 1.418 ± 0.035	1.233TyrThr: 1.233 ± 0.033	1.861TyrVal: 1.861 ± 0.038	0.402TyrTrp: 0.402 ± 0.017	0.783TyrTyr: 0.783 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3931 proteins (1331285 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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