Amino acid dipepetide frequency for Cucurbit yellow stunting disorder virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.146AlaAla: 2.146 ± 0.469
0.78AlaCys: 0.78 ± 0.341
3.122AlaAsp: 3.122 ± 1.154
1.756AlaGlu: 1.756 ± 0.688
1.561AlaPhe: 1.561 ± 0.865
1.561AlaGly: 1.561 ± 0.538
0.585AlaHis: 0.585 ± 0.253
3.902AlaIle: 3.902 ± 0.955
3.512AlaLys: 3.512 ± 0.825
3.902AlaLeu: 3.902 ± 0.77
1.561AlaMet: 1.561 ± 0.558
2.537AlaAsn: 2.537 ± 0.404
0.976AlaPro: 0.976 ± 0.315
1.561AlaGln: 1.561 ± 0.494
1.756AlaArg: 1.756 ± 0.446
2.146AlaSer: 2.146 ± 0.471
1.951AlaThr: 1.951 ± 0.706
1.366AlaVal: 1.366 ± 0.424
0.0AlaTrp: 0.0 ± 0.0
1.561AlaTyr: 1.561 ± 0.538
0.0AlaXaa: 0.0 ± 0.0
Cys
1.366CysAla: 1.366 ± 0.585
0.39CysCys: 0.39 ± 0.253
2.146CysAsp: 2.146 ± 0.528
0.78CysGlu: 0.78 ± 0.693
0.195CysPhe: 0.195 ± 0.126
0.976CysGly: 0.976 ± 0.315
0.0CysHis: 0.0 ± 0.0
1.366CysIle: 1.366 ± 0.359
1.366CysLys: 1.366 ± 0.539
1.561CysLeu: 1.561 ± 0.661
0.39CysMet: 0.39 ± 0.32
2.341CysAsn: 2.341 ± 0.615
0.195CysPro: 0.195 ± 0.126
0.78CysGln: 0.78 ± 0.395
0.78CysArg: 0.78 ± 0.317
2.341CysSer: 2.341 ± 0.459
0.78CysThr: 0.78 ± 0.22
1.171CysVal: 1.171 ± 0.507
0.39CysTrp: 0.39 ± 0.205
1.756CysTyr: 1.756 ± 0.293
0.0CysXaa: 0.0 ± 0.0
Asp
1.366AspAla: 1.366 ± 0.556
1.171AspCys: 1.171 ± 0.481
4.098AspAsp: 4.098 ± 1.183
4.293AspGlu: 4.293 ± 0.818
5.268AspPhe: 5.268 ± 1.285
3.902AspGly: 3.902 ± 0.429
1.366AspHis: 1.366 ± 0.632
3.707AspIle: 3.707 ± 0.802
4.098AspLys: 4.098 ± 0.927
7.61AspLeu: 7.61 ± 1.622
2.146AspMet: 2.146 ± 0.556
5.073AspAsn: 5.073 ± 0.84
1.561AspPro: 1.561 ± 0.779
1.171AspGln: 1.171 ± 0.504
3.122AspArg: 3.122 ± 0.802
4.683AspSer: 4.683 ± 0.933
2.146AspThr: 2.146 ± 0.652
6.439AspVal: 6.439 ± 0.75
0.195AspTrp: 0.195 ± 0.202
1.951AspTyr: 1.951 ± 0.614
0.0AspXaa: 0.0 ± 0.0
Glu
1.756GluAla: 1.756 ± 0.52
1.366GluCys: 1.366 ± 0.351
4.488GluAsp: 4.488 ± 0.972
3.707GluGlu: 3.707 ± 0.748
2.537GluPhe: 2.537 ± 0.836
2.146GluGly: 2.146 ± 0.467
2.341GluHis: 2.341 ± 0.875
5.073GluIle: 5.073 ± 0.634
6.634GluLys: 6.634 ± 1.982
4.683GluLeu: 4.683 ± 1.113
0.976GluMet: 0.976 ± 0.687
2.732GluAsn: 2.732 ± 0.525
0.976GluPro: 0.976 ± 0.434
1.171GluGln: 1.171 ± 0.342
2.732GluArg: 2.732 ± 0.852
3.707GluSer: 3.707 ± 0.649
3.122GluThr: 3.122 ± 0.97
3.122GluVal: 3.122 ± 0.945
0.585GluTrp: 0.585 ± 0.3
2.537GluTyr: 2.537 ± 0.823
0.0GluXaa: 0.0 ± 0.0
Phe
1.951PheAla: 1.951 ± 0.478
1.756PheCys: 1.756 ± 0.277
4.098PheAsp: 4.098 ± 1.09
4.683PheGlu: 4.683 ± 1.218
1.756PhePhe: 1.756 ± 0.759
3.122PheGly: 3.122 ± 1.123
0.0PheHis: 0.0 ± 0.0
2.732PheIle: 2.732 ± 0.472
5.268PheLys: 5.268 ± 1.482
4.683PheLeu: 4.683 ± 1.057
1.951PheMet: 1.951 ± 0.5
1.951PheAsn: 1.951 ± 0.521
1.756PhePro: 1.756 ± 0.824
1.561PheGln: 1.561 ± 0.362
2.341PheArg: 2.341 ± 0.603
6.634PheSer: 6.634 ± 1.326
2.927PheThr: 2.927 ± 1.213
3.512PheVal: 3.512 ± 0.55
0.78PheTrp: 0.78 ± 0.671
2.927PheTyr: 2.927 ± 0.728
0.0PheXaa: 0.0 ± 0.0
Gly
1.366GlyAla: 1.366 ± 0.55
0.78GlyCys: 0.78 ± 0.291
3.122GlyAsp: 3.122 ± 0.565
3.512GlyGlu: 3.512 ± 0.719
2.732GlyPhe: 2.732 ± 0.517
3.902GlyGly: 3.902 ± 1.134
0.0GlyHis: 0.0 ± 0.0
1.951GlyIle: 1.951 ± 0.435
4.878GlyLys: 4.878 ± 0.808
4.098GlyLeu: 4.098 ± 0.903
0.976GlyMet: 0.976 ± 0.436
4.488GlyAsn: 4.488 ± 0.884
0.585GlyPro: 0.585 ± 0.211
0.976GlyGln: 0.976 ± 0.423
2.146GlyArg: 2.146 ± 0.542
3.122GlySer: 3.122 ± 0.546
2.146GlyThr: 2.146 ± 0.587
5.268GlyVal: 5.268 ± 1.177
0.195GlyTrp: 0.195 ± 0.197
1.561GlyTyr: 1.561 ± 0.38
0.0GlyXaa: 0.0 ± 0.0
His
0.585HisAla: 0.585 ± 0.272
0.195HisCys: 0.195 ± 0.243
1.756HisAsp: 1.756 ± 0.416
0.78HisGlu: 0.78 ± 0.41
1.171HisPhe: 1.171 ± 0.485
1.561HisGly: 1.561 ± 0.523
0.585HisHis: 0.585 ± 0.253
0.39HisIle: 0.39 ± 0.321
1.171HisLys: 1.171 ± 0.436
2.146HisLeu: 2.146 ± 0.666
0.976HisMet: 0.976 ± 0.451
0.585HisAsn: 0.585 ± 0.223
1.171HisPro: 1.171 ± 0.399
0.39HisGln: 0.39 ± 0.218
1.366HisArg: 1.366 ± 0.539
0.78HisSer: 0.78 ± 0.334
0.976HisThr: 0.976 ± 0.347
2.146HisVal: 2.146 ± 0.682
0.0HisTrp: 0.0 ± 0.0
1.171HisTyr: 1.171 ± 0.275
0.0HisXaa: 0.0 ± 0.0
Ile
1.561IleAla: 1.561 ± 0.616
1.561IleCys: 1.561 ± 0.825
6.634IleAsp: 6.634 ± 1.279
3.902IleGlu: 3.902 ± 0.947
4.878IlePhe: 4.878 ± 0.921
3.122IleGly: 3.122 ± 0.584
0.78IleHis: 0.78 ± 0.467
5.463IleIle: 5.463 ± 1.007
6.439IleLys: 6.439 ± 0.919
4.683IleLeu: 4.683 ± 0.51
1.171IleMet: 1.171 ± 0.853
4.683IleAsn: 4.683 ± 0.581
3.122IlePro: 3.122 ± 0.683
1.561IleGln: 1.561 ± 0.65
2.927IleArg: 2.927 ± 0.844
6.244IleSer: 6.244 ± 0.567
3.512IleThr: 3.512 ± 1.119
2.537IleVal: 2.537 ± 0.574
0.39IleTrp: 0.39 ± 0.253
3.512IleTyr: 3.512 ± 0.849
0.0IleXaa: 0.0 ± 0.0
Lys
2.927LysAla: 2.927 ± 0.8
1.561LysCys: 1.561 ± 0.469
6.049LysAsp: 6.049 ± 1.212
3.512LysGlu: 3.512 ± 0.734
5.268LysPhe: 5.268 ± 0.999
3.902LysGly: 3.902 ± 0.737
0.78LysHis: 0.78 ± 0.284
4.293LysIle: 4.293 ± 0.418
5.659LysLys: 5.659 ± 0.901
10.927LysLeu: 10.927 ± 1.546
1.951LysMet: 1.951 ± 0.487
4.683LysAsn: 4.683 ± 0.453
3.902LysPro: 3.902 ± 0.759
2.537LysGln: 2.537 ± 0.439
3.707LysArg: 3.707 ± 0.602
7.024LysSer: 7.024 ± 1.101
5.268LysThr: 5.268 ± 0.538
4.878LysVal: 4.878 ± 0.547
0.39LysTrp: 0.39 ± 0.185
4.488LysTyr: 4.488 ± 1.039
0.0LysXaa: 0.0 ± 0.0
Leu
4.488LeuAla: 4.488 ± 0.777
0.78LeuCys: 0.78 ± 0.294
6.634LeuAsp: 6.634 ± 0.9
4.293LeuGlu: 4.293 ± 0.639
5.073LeuPhe: 5.073 ± 1.889
2.341LeuGly: 2.341 ± 0.794
1.756LeuHis: 1.756 ± 0.774
6.634LeuIle: 6.634 ± 0.578
9.366LeuLys: 9.366 ± 0.982
7.805LeuLeu: 7.805 ± 0.985
4.488LeuMet: 4.488 ± 1.175
8.195LeuAsn: 8.195 ± 1.063
2.732LeuPro: 2.732 ± 0.937
2.732LeuGln: 2.732 ± 0.73
4.683LeuArg: 4.683 ± 1.071
6.244LeuSer: 6.244 ± 0.962
5.854LeuThr: 5.854 ± 0.808
7.805LeuVal: 7.805 ± 1.46
0.78LeuTrp: 0.78 ± 0.652
3.902LeuTyr: 3.902 ± 1.064
0.0LeuXaa: 0.0 ± 0.0
Met
0.976MetAla: 0.976 ± 0.434
0.976MetCys: 0.976 ± 0.367
1.561MetAsp: 1.561 ± 0.878
0.976MetGlu: 0.976 ± 0.418
1.756MetPhe: 1.756 ± 0.869
1.171MetGly: 1.171 ± 0.618
0.195MetHis: 0.195 ± 0.229
1.756MetIle: 1.756 ± 0.474
2.146MetLys: 2.146 ± 0.78
1.951MetLeu: 1.951 ± 0.562
0.0MetMet: 0.0 ± 0.0
2.341MetAsn: 2.341 ± 0.646
1.366MetPro: 1.366 ± 0.425
0.976MetGln: 0.976 ± 0.49
0.78MetArg: 0.78 ± 0.413
2.732MetSer: 2.732 ± 0.526
1.561MetThr: 1.561 ± 0.454
1.561MetVal: 1.561 ± 0.507
0.0MetTrp: 0.0 ± 0.0
1.756MetTyr: 1.756 ± 0.611
0.0MetXaa: 0.0 ± 0.0
Asn
2.732AsnAla: 2.732 ± 0.862
1.171AsnCys: 1.171 ± 0.209
2.732AsnAsp: 2.732 ± 0.925
3.317AsnGlu: 3.317 ± 0.645
4.293AsnPhe: 4.293 ± 0.715
2.732AsnGly: 2.732 ± 0.747
1.171AsnHis: 1.171 ± 0.687
5.463AsnIle: 5.463 ± 0.76
6.439AsnLys: 6.439 ± 1.41
7.805AsnLeu: 7.805 ± 1.489
1.366AsnMet: 1.366 ± 0.706
2.732AsnAsn: 2.732 ± 0.834
3.122AsnPro: 3.122 ± 0.561
1.561AsnGln: 1.561 ± 0.438
3.317AsnArg: 3.317 ± 1.021
4.098AsnSer: 4.098 ± 0.822
2.732AsnThr: 2.732 ± 0.737
5.659AsnVal: 5.659 ± 1.078
0.39AsnTrp: 0.39 ± 0.185
2.341AsnTyr: 2.341 ± 0.313
0.0AsnXaa: 0.0 ± 0.0
Pro
1.171ProAla: 1.171 ± 0.51
0.39ProCys: 0.39 ± 0.348
1.366ProAsp: 1.366 ± 0.676
2.341ProGlu: 2.341 ± 0.442
1.561ProPhe: 1.561 ± 0.538
2.146ProGly: 2.146 ± 0.41
0.585ProHis: 0.585 ± 0.253
2.537ProIle: 2.537 ± 0.662
2.927ProLys: 2.927 ± 1.022
1.756ProLeu: 1.756 ± 0.668
0.78ProMet: 0.78 ± 0.467
2.732ProAsn: 2.732 ± 0.518
1.171ProPro: 1.171 ± 0.543
0.39ProGln: 0.39 ± 0.316
1.366ProArg: 1.366 ± 0.365
1.561ProSer: 1.561 ± 0.308
2.927ProThr: 2.927 ± 0.514
1.951ProVal: 1.951 ± 0.607
0.39ProTrp: 0.39 ± 0.267
0.976ProTyr: 0.976 ± 0.475
0.0ProXaa: 0.0 ± 0.0
Gln
1.366GlnAla: 1.366 ± 0.416
0.78GlnCys: 0.78 ± 0.386
1.951GlnAsp: 1.951 ± 0.487
1.366GlnGlu: 1.366 ± 0.488
2.146GlnPhe: 2.146 ± 0.623
1.171GlnGly: 1.171 ± 0.412
0.78GlnHis: 0.78 ± 0.369
2.537GlnIle: 2.537 ± 0.789
1.561GlnLys: 1.561 ± 0.549
1.951GlnLeu: 1.951 ± 0.586
0.39GlnMet: 0.39 ± 0.314
0.585GlnAsn: 0.585 ± 0.298
0.976GlnPro: 0.976 ± 0.499
0.39GlnGln: 0.39 ± 0.232
1.561GlnArg: 1.561 ± 0.513
1.756GlnSer: 1.756 ± 0.569
1.171GlnThr: 1.171 ± 0.478
1.951GlnVal: 1.951 ± 0.553
0.195GlnTrp: 0.195 ± 0.194
1.561GlnTyr: 1.561 ± 0.476
0.0GlnXaa: 0.0 ± 0.0
Arg
2.537ArgAla: 2.537 ± 0.63
0.976ArgCys: 0.976 ± 0.342
2.146ArgAsp: 2.146 ± 0.564
3.122ArgGlu: 3.122 ± 0.829
2.927ArgPhe: 2.927 ± 0.769
2.732ArgGly: 2.732 ± 0.629
1.366ArgHis: 1.366 ± 0.333
2.341ArgIle: 2.341 ± 0.573
1.951ArgLys: 1.951 ± 0.512
6.049ArgLeu: 6.049 ± 1.172
1.171ArgMet: 1.171 ± 0.526
2.927ArgAsn: 2.927 ± 0.779
0.976ArgPro: 0.976 ± 0.462
1.756ArgGln: 1.756 ± 0.378
1.561ArgArg: 1.561 ± 0.77
4.098ArgSer: 4.098 ± 0.684
2.146ArgThr: 2.146 ± 0.423
4.293ArgVal: 4.293 ± 1.038
0.195ArgTrp: 0.195 ± 0.202
2.341ArgTyr: 2.341 ± 0.671
0.0ArgXaa: 0.0 ± 0.0
Ser
3.512SerAla: 3.512 ± 0.801
1.561SerCys: 1.561 ± 0.699
4.098SerAsp: 4.098 ± 0.737
3.122SerGlu: 3.122 ± 0.95
4.293SerPhe: 4.293 ± 0.826
2.146SerGly: 2.146 ± 0.658
2.537SerHis: 2.537 ± 0.588
6.244SerIle: 6.244 ± 1.177
5.854SerLys: 5.854 ± 0.9
8.195SerLeu: 8.195 ± 1.092
1.756SerMet: 1.756 ± 0.466
4.488SerAsn: 4.488 ± 0.819
1.561SerPro: 1.561 ± 0.417
2.341SerGln: 2.341 ± 1.044
2.927SerArg: 2.927 ± 0.627
5.854SerSer: 5.854 ± 0.884
3.707SerThr: 3.707 ± 0.599
6.244SerVal: 6.244 ± 0.967
0.78SerTrp: 0.78 ± 0.337
3.317SerTyr: 3.317 ± 0.653
0.0SerXaa: 0.0 ± 0.0
Thr
1.366ThrAla: 1.366 ± 0.547
1.756ThrCys: 1.756 ± 0.666
2.146ThrAsp: 2.146 ± 0.683
3.512ThrGlu: 3.512 ± 0.629
2.732ThrPhe: 2.732 ± 0.707
2.732ThrGly: 2.732 ± 0.8
1.561ThrHis: 1.561 ± 0.475
3.512ThrIle: 3.512 ± 1.077
4.293ThrLys: 4.293 ± 1.232
5.659ThrLeu: 5.659 ± 0.827
1.366ThrMet: 1.366 ± 0.403
2.537ThrAsn: 2.537 ± 0.674
1.366ThrPro: 1.366 ± 0.396
1.171ThrGln: 1.171 ± 0.6
2.146ThrArg: 2.146 ± 0.377
3.902ThrSer: 3.902 ± 0.817
3.902ThrThr: 3.902 ± 0.839
3.122ThrVal: 3.122 ± 0.703
0.976ThrTrp: 0.976 ± 0.593
1.951ThrTyr: 1.951 ± 0.61
0.0ThrXaa: 0.0 ± 0.0
Val
2.732ValAla: 2.732 ± 0.8
1.561ValCys: 1.561 ± 0.535
3.707ValAsp: 3.707 ± 0.81
4.488ValGlu: 4.488 ± 1.091
2.732ValPhe: 2.732 ± 0.967
3.707ValGly: 3.707 ± 0.818
0.78ValHis: 0.78 ± 0.369
3.902ValIle: 3.902 ± 1.465
6.634ValLys: 6.634 ± 1.086
6.829ValLeu: 6.829 ± 0.844
1.561ValMet: 1.561 ± 0.589
6.244ValAsn: 6.244 ± 1.301
2.341ValPro: 2.341 ± 0.708
1.756ValGln: 1.756 ± 0.766
4.488ValArg: 4.488 ± 1.0
5.268ValSer: 5.268 ± 0.713
2.732ValThr: 2.732 ± 0.578
3.707ValVal: 3.707 ± 0.885
0.195ValTrp: 0.195 ± 0.289
4.293ValTyr: 4.293 ± 0.686
0.0ValXaa: 0.0 ± 0.0
Trp
0.195TrpAla: 0.195 ± 0.194
0.195TrpCys: 0.195 ± 0.197
0.0TrpAsp: 0.0 ± 0.0
0.585TrpGlu: 0.585 ± 0.5
0.39TrpPhe: 0.39 ± 0.232
0.39TrpGly: 0.39 ± 0.253
0.195TrpHis: 0.195 ± 0.126
0.78TrpIle: 0.78 ± 0.462
0.195TrpLys: 0.195 ± 0.262
0.976TrpLeu: 0.976 ± 0.469
0.585TrpMet: 0.585 ± 0.342
0.195TrpAsn: 0.195 ± 0.229
0.0TrpPro: 0.0 ± 0.0
0.195TrpGln: 0.195 ± 0.254
0.976TrpArg: 0.976 ± 0.76
0.39TrpSer: 0.39 ± 0.394
0.195TrpThr: 0.195 ± 0.126
0.195TrpVal: 0.195 ± 0.202
0.195TrpTrp: 0.195 ± 0.197
0.195TrpTyr: 0.195 ± 0.126
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.146TyrAla: 2.146 ± 0.701
1.366TyrCys: 1.366 ± 0.302
3.512TyrAsp: 3.512 ± 0.855
2.341TyrGlu: 2.341 ± 0.657
3.122TyrPhe: 3.122 ± 0.517
2.341TyrGly: 2.341 ± 0.997
2.537TyrHis: 2.537 ± 0.729
4.098TyrIle: 4.098 ± 0.984
3.317TyrLys: 3.317 ± 0.921
3.317TyrLeu: 3.317 ± 0.643
0.78TyrMet: 0.78 ± 0.376
3.317TyrAsn: 3.317 ± 0.914
1.171TyrPro: 1.171 ± 0.275
1.171TyrGln: 1.171 ± 0.353
2.927TyrArg: 2.927 ± 0.742
1.951TyrSer: 1.951 ± 0.714
1.951TyrThr: 1.951 ± 0.677
2.732TyrVal: 2.732 ± 0.733
0.0TyrTrp: 0.0 ± 0.0
2.341TyrTyr: 2.341 ± 0.659
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (5126 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski