Amino acid dipepetide frequency for Apis mellifera associated microvirus 36

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.456AlaAla: 9.456 ± 6.164
0.0AlaCys: 0.0 ± 0.0
4.728AlaAsp: 4.728 ± 1.323
5.516AlaGlu: 5.516 ± 2.395
0.788AlaPhe: 0.788 ± 0.771
5.516AlaGly: 5.516 ± 1.685
1.576AlaHis: 1.576 ± 1.13
2.364AlaIle: 2.364 ± 1.692
6.304AlaLys: 6.304 ± 4.52
4.728AlaLeu: 4.728 ± 0.834
1.576AlaMet: 1.576 ± 1.13
4.728AlaAsn: 4.728 ± 1.187
6.304AlaPro: 6.304 ± 2.757
3.94AlaGln: 3.94 ± 2.941
3.152AlaArg: 3.152 ± 2.18
3.152AlaSer: 3.152 ± 0.821
3.152AlaThr: 3.152 ± 3.548
2.364AlaVal: 2.364 ± 1.325
1.576AlaTrp: 1.576 ± 0.665
3.152AlaTyr: 3.152 ± 0.755
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.788CysGly: 0.788 ± 0.771
0.788CysHis: 0.788 ± 1.073
0.0CysIle: 0.0 ± 0.0
0.788CysLys: 0.788 ± 1.073
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.576CysGln: 1.576 ± 1.09
0.788CysArg: 0.788 ± 1.073
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.788CysTyr: 0.788 ± 0.771
0.0CysXaa: 0.0 ± 0.0
Asp
2.364AspAla: 2.364 ± 1.635
0.0AspCys: 0.0 ± 0.0
0.788AspAsp: 0.788 ± 0.771
2.364AspGlu: 2.364 ± 1.635
3.152AspPhe: 3.152 ± 1.347
4.728AspGly: 4.728 ± 2.407
0.788AspHis: 0.788 ± 0.771
1.576AspIle: 1.576 ± 0.665
7.092AspLys: 7.092 ± 4.619
4.728AspLeu: 4.728 ± 1.544
0.788AspMet: 0.788 ± 0.805
2.364AspAsn: 2.364 ± 0.912
3.152AspPro: 3.152 ± 0.948
1.576AspGln: 1.576 ± 0.784
1.576AspArg: 1.576 ± 1.132
1.576AspSer: 1.576 ± 0.82
3.152AspThr: 3.152 ± 1.33
0.788AspVal: 0.788 ± 0.545
0.788AspTrp: 0.788 ± 0.771
4.728AspTyr: 4.728 ± 1.605
0.0AspXaa: 0.0 ± 0.0
Glu
6.304GluAla: 6.304 ± 4.29
0.0GluCys: 0.0 ± 0.0
3.152GluAsp: 3.152 ± 1.561
3.152GluGlu: 3.152 ± 1.652
1.576GluPhe: 1.576 ± 0.82
3.152GluGly: 3.152 ± 0.755
2.364GluHis: 2.364 ± 1.108
3.152GluIle: 3.152 ± 0.948
9.456GluLys: 9.456 ± 5.72
8.668GluLeu: 8.668 ± 2.285
1.576GluMet: 1.576 ± 1.609
4.728GluAsn: 4.728 ± 0.977
2.364GluPro: 2.364 ± 0.677
1.576GluGln: 1.576 ± 1.09
4.728GluArg: 4.728 ± 2.911
0.788GluSer: 0.788 ± 0.939
5.516GluThr: 5.516 ± 1.176
2.364GluVal: 2.364 ± 1.635
0.788GluTrp: 0.788 ± 0.545
3.94GluTyr: 3.94 ± 1.129
0.0GluXaa: 0.0 ± 0.0
Phe
3.152PheAla: 3.152 ± 1.433
0.0PheCys: 0.0 ± 0.0
2.364PheAsp: 2.364 ± 1.108
2.364PheGlu: 2.364 ± 0.889
2.364PhePhe: 2.364 ± 1.108
3.152PheGly: 3.152 ± 2.18
0.788PheHis: 0.788 ± 0.771
1.576PheIle: 1.576 ± 1.09
4.728PheLys: 4.728 ± 1.469
1.576PheLeu: 1.576 ± 0.97
2.364PheMet: 2.364 ± 0.926
4.728PheAsn: 4.728 ± 1.654
0.0PhePro: 0.0 ± 0.0
1.576PheGln: 1.576 ± 0.665
3.152PheArg: 3.152 ± 1.347
0.788PheSer: 0.788 ± 0.545
1.576PheThr: 1.576 ± 0.784
0.788PheVal: 0.788 ± 0.545
0.788PheTrp: 0.788 ± 0.545
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.516GlyAla: 5.516 ± 2.168
0.0GlyCys: 0.0 ± 0.0
3.152GlyAsp: 3.152 ± 1.561
4.728GlyGlu: 4.728 ± 2.351
3.152GlyPhe: 3.152 ± 0.847
5.516GlyGly: 5.516 ± 2.134
0.788GlyHis: 0.788 ± 0.545
5.516GlyIle: 5.516 ± 2.038
2.364GlyLys: 2.364 ± 0.912
6.304GlyLeu: 6.304 ± 2.252
0.788GlyMet: 0.788 ± 0.805
3.152GlyAsn: 3.152 ± 1.264
0.788GlyPro: 0.788 ± 0.545
0.788GlyGln: 0.788 ± 0.545
5.516GlyArg: 5.516 ± 4.046
6.304GlySer: 6.304 ± 2.488
5.516GlyThr: 5.516 ± 2.188
6.304GlyVal: 6.304 ± 2.893
0.0GlyTrp: 0.0 ± 0.0
4.728GlyTyr: 4.728 ± 1.018
0.0GlyXaa: 0.0 ± 0.0
His
4.728HisAla: 4.728 ± 3.057
0.0HisCys: 0.0 ± 0.0
2.364HisAsp: 2.364 ± 1.553
1.576HisGlu: 1.576 ± 0.784
1.576HisPhe: 1.576 ± 0.784
2.364HisGly: 2.364 ± 1.635
0.788HisHis: 0.788 ± 0.545
0.0HisIle: 0.0 ± 0.0
2.364HisLys: 2.364 ± 1.456
2.364HisLeu: 2.364 ± 1.557
0.788HisMet: 0.788 ± 0.726
0.788HisAsn: 0.788 ± 0.771
0.0HisPro: 0.0 ± 0.0
0.788HisGln: 0.788 ± 0.771
2.364HisArg: 2.364 ± 1.635
1.576HisSer: 1.576 ± 1.13
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.788HisTrp: 0.788 ± 0.771
2.364HisTyr: 2.364 ± 1.456
0.0HisXaa: 0.0 ± 0.0
Ile
3.94IleAla: 3.94 ± 2.941
0.0IleCys: 0.0 ± 0.0
3.152IleAsp: 3.152 ± 1.347
3.94IleGlu: 3.94 ± 1.224
3.152IlePhe: 3.152 ± 1.29
7.092IleGly: 7.092 ± 1.986
0.788IleHis: 0.788 ± 0.771
3.152IleIle: 3.152 ± 0.755
2.364IleLys: 2.364 ± 1.005
3.152IleLeu: 3.152 ± 1.428
2.364IleMet: 2.364 ± 0.885
2.364IleAsn: 2.364 ± 0.677
3.152IlePro: 3.152 ± 1.124
0.788IleGln: 0.788 ± 0.939
3.94IleArg: 3.94 ± 1.296
4.728IleSer: 4.728 ± 1.605
3.152IleThr: 3.152 ± 0.755
1.576IleVal: 1.576 ± 0.82
1.576IleTrp: 1.576 ± 0.784
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
6.304LysAla: 6.304 ± 4.667
0.0LysCys: 0.0 ± 0.0
3.94LysAsp: 3.94 ± 2.133
10.244LysGlu: 10.244 ± 5.221
3.94LysPhe: 3.94 ± 1.499
2.364LysGly: 2.364 ± 1.741
1.576LysHis: 1.576 ± 1.13
6.304LysIle: 6.304 ± 1.793
3.152LysLys: 3.152 ± 1.652
4.728LysLeu: 4.728 ± 1.59
1.576LysMet: 1.576 ± 0.665
2.364LysAsn: 2.364 ± 0.677
5.516LysPro: 5.516 ± 3.549
3.152LysGln: 3.152 ± 1.264
3.152LysArg: 3.152 ± 0.948
1.576LysSer: 1.576 ± 0.97
3.152LysThr: 3.152 ± 1.584
1.576LysVal: 1.576 ± 1.543
1.576LysTrp: 1.576 ± 1.543
1.576LysTyr: 1.576 ± 0.82
0.0LysXaa: 0.0 ± 0.0
Leu
4.728LeuAla: 4.728 ± 1.902
0.0LeuCys: 0.0 ± 0.0
3.152LeuAsp: 3.152 ± 1.561
7.88LeuGlu: 7.88 ± 2.869
2.364LeuPhe: 2.364 ± 0.912
3.94LeuGly: 3.94 ± 1.574
2.364LeuHis: 2.364 ± 1.456
2.364LeuIle: 2.364 ± 1.079
3.94LeuLys: 3.94 ± 2.916
3.94LeuLeu: 3.94 ± 1.5
2.364LeuMet: 2.364 ± 0.918
7.092LeuAsn: 7.092 ± 2.348
7.88LeuPro: 7.88 ± 2.031
5.516LeuGln: 5.516 ± 2.603
4.728LeuArg: 4.728 ± 1.702
3.94LeuSer: 3.94 ± 1.5
3.94LeuThr: 3.94 ± 1.296
2.364LeuVal: 2.364 ± 2.414
0.788LeuTrp: 0.788 ± 0.545
3.152LeuTyr: 3.152 ± 1.428
0.0LeuXaa: 0.0 ± 0.0
Met
2.364MetAla: 2.364 ± 0.677
0.788MetCys: 0.788 ± 0.545
1.576MetAsp: 1.576 ± 1.13
0.788MetGlu: 0.788 ± 0.805
0.788MetPhe: 0.788 ± 0.771
3.94MetGly: 3.94 ± 1.5
1.576MetHis: 1.576 ± 0.784
1.576MetIle: 1.576 ± 0.665
2.364MetLys: 2.364 ± 1.884
0.788MetLeu: 0.788 ± 0.805
0.0MetMet: 0.0 ± 0.0
2.364MetAsn: 2.364 ± 0.926
3.152MetPro: 3.152 ± 2.18
0.0MetGln: 0.0 ± 0.0
1.576MetArg: 1.576 ± 1.09
1.576MetSer: 1.576 ± 0.82
0.788MetThr: 0.788 ± 0.545
0.0MetVal: 0.0 ± 0.0
1.576MetTrp: 1.576 ± 0.665
1.576MetTyr: 1.576 ± 1.289
0.0MetXaa: 0.0 ± 0.0
Asn
4.728AsnAla: 4.728 ± 1.018
0.788AsnCys: 0.788 ± 0.771
2.364AsnAsp: 2.364 ± 1.635
4.728AsnGlu: 4.728 ± 1.323
1.576AsnPhe: 1.576 ± 0.784
2.364AsnGly: 2.364 ± 1.005
0.0AsnHis: 0.0 ± 0.0
3.94AsnIle: 3.94 ± 1.5
4.728AsnLys: 4.728 ± 1.004
4.728AsnLeu: 4.728 ± 1.995
0.788AsnMet: 0.788 ± 0.545
3.152AsnAsn: 3.152 ± 0.821
5.516AsnPro: 5.516 ± 3.034
2.364AsnGln: 2.364 ± 1.372
7.092AsnArg: 7.092 ± 3.739
1.576AsnSer: 1.576 ± 0.784
4.728AsnThr: 4.728 ± 2.004
4.728AsnVal: 4.728 ± 1.772
0.0AsnTrp: 0.0 ± 0.0
0.788AsnTyr: 0.788 ± 0.545
0.0AsnXaa: 0.0 ± 0.0
Pro
2.364ProAla: 2.364 ± 0.912
1.576ProCys: 1.576 ± 1.132
2.364ProAsp: 2.364 ± 1.677
4.728ProGlu: 4.728 ± 1.59
2.364ProPhe: 2.364 ± 1.005
4.728ProGly: 4.728 ± 1.826
1.576ProHis: 1.576 ± 1.543
3.152ProIle: 3.152 ± 1.33
1.576ProLys: 1.576 ± 0.784
3.94ProLeu: 3.94 ± 3.13
2.364ProMet: 2.364 ± 1.635
2.364ProAsn: 2.364 ± 1.884
0.788ProPro: 0.788 ± 0.939
0.788ProGln: 0.788 ± 0.545
3.152ProArg: 3.152 ± 0.847
4.728ProSer: 4.728 ± 0.692
7.092ProThr: 7.092 ± 3.027
2.364ProVal: 2.364 ± 1.635
1.576ProTrp: 1.576 ± 1.076
2.364ProTyr: 2.364 ± 1.005
0.0ProXaa: 0.0 ± 0.0
Gln
6.304GlnAla: 6.304 ± 2.863
0.0GlnCys: 0.0 ± 0.0
2.364GlnAsp: 2.364 ± 0.912
4.728GlnGlu: 4.728 ± 1.534
0.0GlnPhe: 0.0 ± 0.0
0.788GlnGly: 0.788 ± 0.545
0.788GlnHis: 0.788 ± 0.939
3.94GlnIle: 3.94 ± 1.129
1.576GlnLys: 1.576 ± 0.97
4.728GlnLeu: 4.728 ± 2.786
2.364GlnMet: 2.364 ± 1.372
2.364GlnAsn: 2.364 ± 1.372
1.576GlnPro: 1.576 ± 0.82
0.0GlnGln: 0.0 ± 0.0
3.152GlnArg: 3.152 ± 1.124
1.576GlnSer: 1.576 ± 1.09
2.364GlnThr: 2.364 ± 1.635
1.576GlnVal: 1.576 ± 1.076
1.576GlnTrp: 1.576 ± 0.97
0.788GlnTyr: 0.788 ± 0.805
0.0GlnXaa: 0.0 ± 0.0
Arg
2.364ArgAla: 2.364 ± 1.635
0.0ArgCys: 0.0 ± 0.0
2.364ArgAsp: 2.364 ± 1.005
2.364ArgGlu: 2.364 ± 0.926
0.788ArgPhe: 0.788 ± 0.805
5.516ArgGly: 5.516 ± 1.711
0.788ArgHis: 0.788 ± 1.073
5.516ArgIle: 5.516 ± 1.717
5.516ArgLys: 5.516 ± 0.98
4.728ArgLeu: 4.728 ± 1.388
2.364ArgMet: 2.364 ± 1.467
3.152ArgAsn: 3.152 ± 1.264
4.728ArgPro: 4.728 ± 1.939
4.728ArgGln: 4.728 ± 4.155
3.152ArgArg: 3.152 ± 1.124
1.576ArgSer: 1.576 ± 0.784
3.94ArgThr: 3.94 ± 1.398
3.152ArgVal: 3.152 ± 1.567
0.788ArgTrp: 0.788 ± 1.073
6.304ArgTyr: 6.304 ± 1.732
0.0ArgXaa: 0.0 ± 0.0
Ser
2.364SerAla: 2.364 ± 0.912
0.788SerCys: 0.788 ± 1.073
3.94SerAsp: 3.94 ± 0.528
2.364SerGlu: 2.364 ± 1.029
3.152SerPhe: 3.152 ± 0.86
2.364SerGly: 2.364 ± 0.912
1.576SerHis: 1.576 ± 0.82
3.152SerIle: 3.152 ± 1.448
3.152SerLys: 3.152 ± 1.448
3.152SerLeu: 3.152 ± 0.755
0.788SerMet: 0.788 ± 0.545
4.728SerAsn: 4.728 ± 1.772
2.364SerPro: 2.364 ± 1.408
2.364SerGln: 2.364 ± 1.408
4.728SerArg: 4.728 ± 1.354
3.152SerSer: 3.152 ± 1.347
3.152SerThr: 3.152 ± 2.18
3.152SerVal: 3.152 ± 1.33
0.788SerTrp: 0.788 ± 0.545
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.152ThrAla: 3.152 ± 0.948
0.788ThrCys: 0.788 ± 1.073
2.364ThrAsp: 2.364 ± 0.912
2.364ThrGlu: 2.364 ± 0.912
2.364ThrPhe: 2.364 ± 1.108
3.94ThrGly: 3.94 ± 1.099
3.94ThrHis: 3.94 ± 2.208
3.152ThrIle: 3.152 ± 0.847
0.788ThrLys: 0.788 ± 0.771
5.516ThrLeu: 5.516 ± 1.78
0.788ThrMet: 0.788 ± 0.545
3.94ThrAsn: 3.94 ± 1.933
3.94ThrPro: 3.94 ± 2.725
3.152ThrGln: 3.152 ± 0.86
3.94ThrArg: 3.94 ± 1.361
7.092ThrSer: 7.092 ± 3.027
6.304ThrThr: 6.304 ± 2.488
3.94ThrVal: 3.94 ± 1.265
0.788ThrTrp: 0.788 ± 0.805
2.364ThrTyr: 2.364 ± 1.289
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
1.576ValAsp: 1.576 ± 1.289
1.576ValGlu: 1.576 ± 0.665
0.0ValPhe: 0.0 ± 0.0
3.94ValGly: 3.94 ± 2.389
1.576ValHis: 1.576 ± 0.784
2.364ValIle: 2.364 ± 0.912
3.152ValLys: 3.152 ± 1.264
4.728ValLeu: 4.728 ± 1.939
2.364ValMet: 2.364 ± 1.635
3.94ValAsn: 3.94 ± 2.059
2.364ValPro: 2.364 ± 1.029
1.576ValGln: 1.576 ± 0.784
0.788ValArg: 0.788 ± 0.545
1.576ValSer: 1.576 ± 0.82
3.94ValThr: 3.94 ± 1.265
1.576ValVal: 1.576 ± 1.076
0.788ValTrp: 0.788 ± 0.545
2.364ValTyr: 2.364 ± 0.912
0.0ValXaa: 0.0 ± 0.0
Trp
1.576TrpAla: 1.576 ± 2.146
0.0TrpCys: 0.0 ± 0.0
1.576TrpAsp: 1.576 ± 1.09
0.788TrpGlu: 0.788 ± 0.545
0.0TrpPhe: 0.0 ± 0.0
1.576TrpGly: 1.576 ± 0.665
1.576TrpHis: 1.576 ± 0.784
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.576TrpLeu: 1.576 ± 0.784
0.788TrpMet: 0.788 ± 0.805
0.788TrpAsn: 0.788 ± 0.805
2.364TrpPro: 2.364 ± 1.108
1.576TrpGln: 1.576 ± 0.97
0.788TrpArg: 0.788 ± 0.771
1.576TrpSer: 1.576 ± 1.09
0.788TrpThr: 0.788 ± 0.771
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.364TyrAla: 2.364 ± 0.889
0.788TyrCys: 0.788 ± 0.545
0.788TyrAsp: 0.788 ± 0.939
3.152TyrGlu: 3.152 ± 0.821
4.728TyrPhe: 4.728 ± 2.576
3.152TyrGly: 3.152 ± 1.584
2.364TyrHis: 2.364 ± 0.677
1.576TyrIle: 1.576 ± 0.784
2.364TyrLys: 2.364 ± 0.926
2.364TyrLeu: 2.364 ± 1.108
1.576TyrMet: 1.576 ± 1.09
1.576TyrAsn: 1.576 ± 1.609
0.0TyrPro: 0.0 ± 0.0
4.728TyrGln: 4.728 ± 1.501
2.364TyrArg: 2.364 ± 0.677
2.364TyrSer: 2.364 ± 1.221
2.364TyrThr: 2.364 ± 0.677
1.576TyrVal: 1.576 ± 0.784
0.788TyrTrp: 0.788 ± 0.545
1.576TyrTyr: 1.576 ± 0.784
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski