Amino acid dipepetide frequency for Grapevine virus A (isolate Is 151) (GVA)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.408AlaAla: 0.408 ± 0.205
0.817AlaCys: 0.817 ± 0.527
1.633AlaAsp: 1.633 ± 0.527
3.675AlaGlu: 3.675 ± 1.371
2.858AlaPhe: 2.858 ± 0.948
4.492AlaGly: 4.492 ± 2.251
2.45AlaHis: 2.45 ± 0.876
4.492AlaIle: 4.492 ± 1.366
5.717AlaLys: 5.717 ± 2.032
8.167AlaLeu: 8.167 ± 1.107
1.633AlaMet: 1.633 ± 0.695
1.633AlaAsn: 1.633 ± 0.819
0.817AlaPro: 0.817 ± 0.409
2.45AlaGln: 2.45 ± 2.191
2.858AlaArg: 2.858 ± 1.071
3.675AlaSer: 3.675 ± 2.357
4.083AlaThr: 4.083 ± 2.452
2.45AlaVal: 2.45 ± 1.515
0.0AlaTrp: 0.0 ± 0.0
1.225AlaTyr: 1.225 ± 0.683
0.0AlaXaa: 0.0 ± 0.0
Cys
1.225CysAla: 1.225 ± 0.486
0.0CysCys: 0.0 ± 0.0
0.817CysAsp: 0.817 ± 1.237
1.633CysGlu: 1.633 ± 0.695
0.817CysPhe: 0.817 ± 0.409
1.225CysGly: 1.225 ± 0.936
0.408CysHis: 0.408 ± 0.205
1.225CysIle: 1.225 ± 0.486
2.042CysLys: 2.042 ± 1.51
1.633CysLeu: 1.633 ± 0.819
0.817CysMet: 0.817 ± 0.409
0.817CysAsn: 0.817 ± 0.854
0.0CysPro: 0.0 ± 0.0
0.408CysGln: 0.408 ± 0.205
0.817CysArg: 0.817 ± 0.409
2.042CysSer: 2.042 ± 1.023
0.817CysThr: 0.817 ± 0.854
0.817CysVal: 0.817 ± 1.237
0.0CysTrp: 0.0 ± 0.0
0.817CysTyr: 0.817 ± 0.409
0.0CysXaa: 0.0 ± 0.0
Asp
2.042AspAla: 2.042 ± 0.764
1.225AspCys: 1.225 ± 1.651
5.717AspAsp: 5.717 ± 1.298
7.35AspGlu: 7.35 ± 2.64
2.042AspPhe: 2.042 ± 1.567
4.492AspGly: 4.492 ± 1.953
0.817AspHis: 0.817 ± 0.409
4.083AspIle: 4.083 ± 1.426
2.042AspLys: 2.042 ± 0.635
6.942AspLeu: 6.942 ± 3.675
1.225AspMet: 1.225 ± 1.321
1.225AspAsn: 1.225 ± 0.486
2.45AspPro: 2.45 ± 0.896
0.817AspGln: 0.817 ± 0.409
3.675AspArg: 3.675 ± 1.092
4.083AspSer: 4.083 ± 2.265
2.858AspThr: 2.858 ± 0.992
4.9AspVal: 4.9 ± 1.565
1.225AspTrp: 1.225 ± 0.614
3.267AspTyr: 3.267 ± 1.088
0.0AspXaa: 0.0 ± 0.0
Glu
6.942GluAla: 6.942 ± 1.7
1.633GluCys: 1.633 ± 0.819
6.533GluAsp: 6.533 ± 2.251
6.942GluGlu: 6.942 ± 1.835
2.042GluPhe: 2.042 ± 0.792
5.717GluGly: 5.717 ± 2.524
1.225GluHis: 1.225 ± 0.614
7.35GluIle: 7.35 ± 1.898
5.717GluLys: 5.717 ± 2.303
7.35GluLeu: 7.35 ± 0.821
2.042GluMet: 2.042 ± 0.752
2.042GluAsn: 2.042 ± 1.023
4.9GluPro: 4.9 ± 1.345
1.225GluGln: 1.225 ± 0.683
2.042GluArg: 2.042 ± 0.762
4.492GluSer: 4.492 ± 1.168
5.717GluThr: 5.717 ± 2.368
5.308GluVal: 5.308 ± 1.209
0.0GluTrp: 0.0 ± 0.0
2.042GluTyr: 2.042 ± 0.895
0.0GluXaa: 0.0 ± 0.0
Phe
2.858PheAla: 2.858 ± 1.474
0.817PheCys: 0.817 ± 0.527
2.042PheAsp: 2.042 ± 0.764
3.267PheGlu: 3.267 ± 0.998
1.225PhePhe: 1.225 ± 0.614
2.858PheGly: 2.858 ± 0.678
1.225PheHis: 1.225 ± 1.071
1.225PheIle: 1.225 ± 0.486
2.042PheLys: 2.042 ± 0.764
3.675PheLeu: 3.675 ± 1.768
1.633PheMet: 1.633 ± 0.819
1.633PheAsn: 1.633 ± 0.695
2.45PhePro: 2.45 ± 1.581
0.408PheGln: 0.408 ± 0.205
2.858PheArg: 2.858 ± 0.709
4.083PheSer: 4.083 ± 0.892
1.225PheThr: 1.225 ± 0.614
1.225PheVal: 1.225 ± 0.936
0.0PheTrp: 0.0 ± 0.0
1.225PheTyr: 1.225 ± 0.614
0.0PheXaa: 0.0 ± 0.0
Gly
4.083GlyAla: 4.083 ± 1.535
1.225GlyCys: 1.225 ± 0.486
5.717GlyAsp: 5.717 ± 1.298
6.942GlyGlu: 6.942 ± 2.902
1.633GlyPhe: 1.633 ± 0.695
3.267GlyGly: 3.267 ± 1.478
2.042GlyHis: 2.042 ± 0.762
4.083GlyIle: 4.083 ± 1.309
4.492GlyLys: 4.492 ± 1.005
4.492GlyLeu: 4.492 ± 1.568
0.817GlyMet: 0.817 ± 0.409
2.042GlyAsn: 2.042 ± 1.023
1.633GlyPro: 1.633 ± 1.46
0.408GlyGln: 0.408 ± 0.205
5.308GlyArg: 5.308 ± 2.13
6.942GlySer: 6.942 ± 3.734
2.858GlyThr: 2.858 ± 1.754
4.9GlyVal: 4.9 ± 1.28
1.225GlyTrp: 1.225 ± 0.614
5.308GlyTyr: 5.308 ± 1.756
0.0GlyXaa: 0.0 ± 0.0
His
1.633HisAla: 1.633 ± 0.819
0.817HisCys: 0.817 ± 0.409
0.817HisAsp: 0.817 ± 0.409
0.408HisGlu: 0.408 ± 0.205
0.817HisPhe: 0.817 ± 0.409
2.858HisGly: 2.858 ± 1.574
1.225HisHis: 1.225 ± 0.614
1.633HisIle: 1.633 ± 0.804
1.633HisLys: 1.633 ± 0.835
2.45HisLeu: 2.45 ± 0.782
1.225HisMet: 1.225 ± 0.614
0.408HisAsn: 0.408 ± 0.827
0.817HisPro: 0.817 ± 0.527
1.225HisGln: 1.225 ± 0.486
2.858HisArg: 2.858 ± 0.951
2.858HisSer: 2.858 ± 0.709
1.633HisThr: 1.633 ± 0.819
2.042HisVal: 2.042 ± 0.993
0.817HisTrp: 0.817 ± 0.409
0.817HisTyr: 0.817 ± 1.654
0.0HisXaa: 0.0 ± 0.0
Ile
3.267IleAla: 3.267 ± 1.178
0.408IleCys: 0.408 ± 0.205
3.675IleAsp: 3.675 ± 0.777
6.533IleGlu: 6.533 ± 2.092
1.225IlePhe: 1.225 ± 0.772
3.675IleGly: 3.675 ± 1.478
3.675IleHis: 3.675 ± 0.863
1.633IleIle: 1.633 ± 0.695
4.492IleLys: 4.492 ± 1.41
4.9IleLeu: 4.9 ± 3.146
1.225IleMet: 1.225 ± 1.311
1.633IleAsn: 1.633 ± 0.527
1.225IlePro: 1.225 ± 0.486
1.225IleGln: 1.225 ± 0.683
2.042IleArg: 2.042 ± 0.764
3.675IleSer: 3.675 ± 1.035
3.267IleThr: 3.267 ± 1.053
3.267IleVal: 3.267 ± 1.199
0.0IleTrp: 0.0 ± 0.0
2.45IleTyr: 2.45 ± 1.08
0.0IleXaa: 0.0 ± 0.0
Lys
6.942LysAla: 6.942 ± 2.574
0.817LysCys: 0.817 ± 1.068
4.083LysAsp: 4.083 ± 1.069
5.717LysGlu: 5.717 ± 1.875
1.225LysPhe: 1.225 ± 0.486
5.717LysGly: 5.717 ± 1.276
2.45LysHis: 2.45 ± 1.228
3.267LysIle: 3.267 ± 1.637
7.758LysLys: 7.758 ± 0.82
4.083LysLeu: 4.083 ± 1.683
3.267LysMet: 3.267 ± 1.295
1.225LysAsn: 1.225 ± 0.486
1.633LysPro: 1.633 ± 0.527
0.817LysGln: 0.817 ± 0.409
4.492LysArg: 4.492 ± 0.856
4.9LysSer: 4.9 ± 1.512
3.267LysThr: 3.267 ± 0.98
4.9LysVal: 4.9 ± 1.915
0.817LysTrp: 0.817 ± 0.766
2.042LysTyr: 2.042 ± 1.023
0.0LysXaa: 0.0 ± 0.0
Leu
5.308LeuAla: 5.308 ± 1.262
2.042LeuCys: 2.042 ± 0.762
7.35LeuAsp: 7.35 ± 0.757
3.267LeuGlu: 3.267 ± 1.132
4.9LeuPhe: 4.9 ± 1.752
6.533LeuGly: 6.533 ± 5.907
2.45LeuHis: 2.45 ± 1.581
5.308LeuIle: 5.308 ± 1.078
9.392LeuLys: 9.392 ± 2.605
6.942LeuLeu: 6.942 ± 2.062
2.042LeuMet: 2.042 ± 1.672
2.45LeuAsn: 2.45 ± 1.865
3.675LeuPro: 3.675 ± 1.246
2.858LeuGln: 2.858 ± 1.4
8.983LeuArg: 8.983 ± 1.907
8.167LeuSer: 8.167 ± 3.548
4.083LeuThr: 4.083 ± 1.537
6.533LeuVal: 6.533 ± 2.516
0.408LeuTrp: 0.408 ± 0.205
4.9LeuTyr: 4.9 ± 1.33
0.0LeuXaa: 0.0 ± 0.0
Met
0.817MetAla: 0.817 ± 1.654
1.225MetCys: 1.225 ± 0.683
3.267MetAsp: 3.267 ± 1.041
2.45MetGlu: 2.45 ± 1.228
0.817MetPhe: 0.817 ± 0.73
2.45MetGly: 2.45 ± 0.876
1.225MetHis: 1.225 ± 1.08
1.225MetIle: 1.225 ± 0.614
1.225MetLys: 1.225 ± 0.486
1.633MetLeu: 1.633 ± 0.527
1.225MetMet: 1.225 ± 0.614
0.817MetAsn: 0.817 ± 0.766
0.817MetPro: 0.817 ± 1.271
1.225MetGln: 1.225 ± 0.614
1.225MetArg: 1.225 ± 0.683
2.45MetSer: 2.45 ± 1.581
1.225MetThr: 1.225 ± 1.142
1.633MetVal: 1.633 ± 0.695
0.0MetTrp: 0.0 ± 0.0
0.817MetTyr: 0.817 ± 0.73
0.0MetXaa: 0.0 ± 0.0
Asn
2.45AsnAla: 2.45 ± 1.365
0.408AsnCys: 0.408 ± 0.205
1.225AsnAsp: 1.225 ± 0.614
1.225AsnGlu: 1.225 ± 0.486
1.633AsnPhe: 1.633 ± 0.819
2.858AsnGly: 2.858 ± 0.992
0.817AsnHis: 0.817 ± 0.409
0.817AsnIle: 0.817 ± 0.527
2.45AsnLys: 2.45 ± 1.186
4.492AsnLeu: 4.492 ± 1.039
2.042AsnMet: 2.042 ± 0.685
1.225AsnAsn: 1.225 ± 1.316
1.225AsnPro: 1.225 ± 0.614
0.817AsnGln: 0.817 ± 0.409
2.858AsnArg: 2.858 ± 0.951
0.817AsnSer: 0.817 ± 0.854
2.858AsnThr: 2.858 ± 1.055
1.225AsnVal: 1.225 ± 0.758
0.0AsnTrp: 0.0 ± 0.0
1.633AsnTyr: 1.633 ± 0.819
0.0AsnXaa: 0.0 ± 0.0
Pro
0.408ProAla: 0.408 ± 0.205
0.408ProCys: 0.408 ± 0.205
1.633ProAsp: 1.633 ± 0.527
2.858ProGlu: 2.858 ± 0.951
2.042ProPhe: 2.042 ± 0.715
2.858ProGly: 2.858 ± 0.951
0.408ProHis: 0.408 ± 0.635
0.817ProIle: 0.817 ± 0.409
1.633ProLys: 1.633 ± 0.695
2.45ProLeu: 2.45 ± 0.971
0.817ProMet: 0.817 ± 0.409
1.633ProAsn: 1.633 ± 0.819
0.408ProPro: 0.408 ± 0.205
1.225ProGln: 1.225 ± 0.947
3.267ProArg: 3.267 ± 1.211
2.042ProSer: 2.042 ± 1.127
2.45ProThr: 2.45 ± 0.666
2.042ProVal: 2.042 ± 0.917
0.408ProTrp: 0.408 ± 0.205
1.225ProTyr: 1.225 ± 0.614
0.0ProXaa: 0.0 ± 0.0
Gln
1.633GlnAla: 1.633 ± 1.802
0.408GlnCys: 0.408 ± 0.973
0.817GlnAsp: 0.817 ± 0.527
2.45GlnGlu: 2.45 ± 1.161
0.408GlnPhe: 0.408 ± 0.635
2.042GlnGly: 2.042 ± 0.635
0.408GlnHis: 0.408 ± 0.205
0.817GlnIle: 0.817 ± 0.409
1.225GlnLys: 1.225 ± 0.486
2.858GlnLeu: 2.858 ± 0.786
0.817GlnMet: 0.817 ± 0.73
1.225GlnAsn: 1.225 ± 0.947
1.225GlnPro: 1.225 ± 0.683
1.225GlnGln: 1.225 ± 0.614
1.225GlnArg: 1.225 ± 0.614
2.858GlnSer: 2.858 ± 0.709
3.267GlnThr: 3.267 ± 1.637
0.817GlnVal: 0.817 ± 1.103
0.0GlnTrp: 0.0 ± 0.0
1.225GlnTyr: 1.225 ± 0.614
0.0GlnXaa: 0.0 ± 0.0
Arg
3.267ArgAla: 3.267 ± 1.019
1.633ArgCys: 1.633 ± 0.819
2.042ArgAsp: 2.042 ± 1.379
4.492ArgGlu: 4.492 ± 2.251
4.083ArgPhe: 4.083 ± 1.662
4.083ArgGly: 4.083 ± 0.854
1.633ArgHis: 1.633 ± 0.739
2.45ArgIle: 2.45 ± 0.702
1.633ArgLys: 1.633 ± 0.819
8.983ArgLeu: 8.983 ± 1.443
2.042ArgMet: 2.042 ± 0.917
2.45ArgAsn: 2.45 ± 0.876
0.408ArgPro: 0.408 ± 0.205
1.633ArgGln: 1.633 ± 0.814
5.308ArgArg: 5.308 ± 3.038
6.533ArgSer: 6.533 ± 1.072
2.858ArgThr: 2.858 ± 2.069
6.125ArgVal: 6.125 ± 1.083
0.408ArgTrp: 0.408 ± 0.205
2.858ArgTyr: 2.858 ± 0.666
0.0ArgXaa: 0.0 ± 0.0
Ser
2.042SerAla: 2.042 ± 0.792
2.042SerCys: 2.042 ± 0.762
4.9SerAsp: 4.9 ± 2.458
7.35SerGlu: 7.35 ± 1.959
3.675SerPhe: 3.675 ± 1.026
5.308SerGly: 5.308 ± 2.828
2.042SerHis: 2.042 ± 0.895
4.492SerIle: 4.492 ± 2.036
6.125SerLys: 6.125 ± 1.414
7.35SerLeu: 7.35 ± 3.77
0.408SerMet: 0.408 ± 0.205
2.45SerAsn: 2.45 ± 1.228
2.45SerPro: 2.45 ± 0.702
2.858SerGln: 2.858 ± 0.678
5.717SerArg: 5.717 ± 2.155
4.083SerSer: 4.083 ± 2.628
3.267SerThr: 3.267 ± 1.041
6.125SerVal: 6.125 ± 0.976
0.817SerTrp: 0.817 ± 0.409
2.45SerTyr: 2.45 ± 1.544
0.0SerXaa: 0.0 ± 0.0
Thr
1.633ThrAla: 1.633 ± 0.819
0.817ThrCys: 0.817 ± 0.409
2.042ThrAsp: 2.042 ± 0.715
5.717ThrGlu: 5.717 ± 1.233
2.858ThrPhe: 2.858 ± 1.071
3.267ThrGly: 3.267 ± 1.815
1.225ThrHis: 1.225 ± 0.614
2.858ThrIle: 2.858 ± 0.951
3.267ThrLys: 3.267 ± 0.98
8.167ThrLeu: 8.167 ± 3.31
0.0ThrMet: 0.0 ± 0.0
2.042ThrAsn: 2.042 ± 0.993
2.45ThrPro: 2.45 ± 1.02
1.633ThrGln: 1.633 ± 0.819
4.083ThrArg: 4.083 ± 2.356
4.083ThrSer: 4.083 ± 1.304
2.042ThrThr: 2.042 ± 0.993
2.858ThrVal: 2.858 ± 1.018
0.817ThrTrp: 0.817 ± 0.766
1.633ThrTyr: 1.633 ± 0.695
0.0ThrXaa: 0.0 ± 0.0
Val
6.125ValAla: 6.125 ± 1.134
1.225ValCys: 1.225 ± 0.758
4.492ValAsp: 4.492 ± 1.432
5.717ValGlu: 5.717 ± 1.587
2.858ValPhe: 2.858 ± 1.729
4.083ValGly: 4.083 ± 2.699
1.633ValHis: 1.633 ± 0.527
3.675ValIle: 3.675 ± 0.945
4.492ValLys: 4.492 ± 2.75
5.717ValLeu: 5.717 ± 1.709
2.858ValMet: 2.858 ± 1.361
3.675ValAsn: 3.675 ± 1.487
0.817ValPro: 0.817 ± 0.527
3.267ValGln: 3.267 ± 2.411
1.633ValArg: 1.633 ± 0.819
3.675ValSer: 3.675 ± 1.259
2.858ValThr: 2.858 ± 0.948
4.083ValVal: 4.083 ± 1.151
0.408ValTrp: 0.408 ± 0.205
2.042ValTyr: 2.042 ± 0.775
0.0ValXaa: 0.0 ± 0.0
Trp
0.817TrpAla: 0.817 ± 0.409
0.408TrpCys: 0.408 ± 0.205
0.408TrpAsp: 0.408 ± 0.205
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.408TrpLys: 0.408 ± 0.205
0.408TrpLeu: 0.408 ± 0.205
0.0TrpMet: 0.0 ± 0.0
0.408TrpAsn: 0.408 ± 0.205
0.817TrpPro: 0.817 ± 0.409
0.0TrpGln: 0.0 ± 0.0
0.408TrpArg: 0.408 ± 0.205
0.408TrpSer: 0.408 ± 0.205
0.408TrpThr: 0.408 ± 0.205
2.042TrpVal: 2.042 ± 1.51
0.0TrpTrp: 0.0 ± 0.0
0.817TrpTyr: 0.817 ± 0.409
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.633TyrAla: 1.633 ± 0.814
0.0TyrCys: 0.0 ± 0.0
3.675TyrAsp: 3.675 ± 1.446
3.267TyrGlu: 3.267 ± 1.637
0.817TyrPhe: 0.817 ± 0.527
1.633TyrGly: 1.633 ± 0.695
1.633TyrHis: 1.633 ± 0.835
2.042TyrIle: 2.042 ± 1.389
1.633TyrLys: 1.633 ± 0.739
4.9TyrLeu: 4.9 ± 1.906
1.225TyrMet: 1.225 ± 0.64
2.042TyrAsn: 2.042 ± 0.635
0.817TyrPro: 0.817 ± 0.409
1.225TyrGln: 1.225 ± 0.772
3.267TyrArg: 3.267 ± 1.1
4.083TyrSer: 4.083 ± 0.883
2.45TyrThr: 2.45 ± 0.782
2.042TyrVal: 2.042 ± 2.671
0.408TyrTrp: 0.408 ± 0.205
0.408TyrTyr: 0.408 ± 0.205
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2450 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski