Amino acid dipepetide frequency for Chenuda virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.695AlaAla: 12.695 ± 1.34
1.953AlaCys: 1.953 ± 0.46
5.046AlaAsp: 5.046 ± 0.704
5.859AlaGlu: 5.859 ± 0.81
3.255AlaPhe: 3.255 ± 0.513
4.72AlaGly: 4.72 ± 1.053
2.93AlaHis: 2.93 ± 0.477
5.859AlaIle: 5.859 ± 0.815
2.604AlaLys: 2.604 ± 0.816
10.742AlaLeu: 10.742 ± 1.678
3.581AlaMet: 3.581 ± 0.915
1.79AlaAsn: 1.79 ± 0.373
6.999AlaPro: 6.999 ± 1.211
3.581AlaGln: 3.581 ± 0.482
8.952AlaArg: 8.952 ± 0.887
6.51AlaSer: 6.51 ± 0.756
5.371AlaThr: 5.371 ± 1.295
6.836AlaVal: 6.836 ± 0.967
1.139AlaTrp: 1.139 ± 0.268
2.604AlaTyr: 2.604 ± 0.442
0.0AlaXaa: 0.0 ± 0.0
Cys
1.628CysAla: 1.628 ± 0.739
0.0CysCys: 0.0 ± 0.0
0.326CysAsp: 0.326 ± 0.29
0.651CysGlu: 0.651 ± 0.399
0.163CysPhe: 0.163 ± 0.139
0.488CysGly: 0.488 ± 0.378
0.163CysHis: 0.163 ± 0.145
0.488CysIle: 0.488 ± 0.232
0.814CysLys: 0.814 ± 0.284
0.488CysLeu: 0.488 ± 0.198
0.163CysMet: 0.163 ± 0.139
0.488CysAsn: 0.488 ± 0.258
0.488CysPro: 0.488 ± 0.21
0.977CysGln: 0.977 ± 0.485
1.628CysArg: 1.628 ± 0.401
0.326CysSer: 0.326 ± 0.224
1.139CysThr: 1.139 ± 0.428
2.441CysVal: 2.441 ± 0.836
0.163CysTrp: 0.163 ± 0.145
0.814CysTyr: 0.814 ± 0.576
0.0CysXaa: 0.0 ± 0.0
Asp
4.395AspAla: 4.395 ± 0.809
0.651AspCys: 0.651 ± 0.213
4.395AspAsp: 4.395 ± 0.817
3.581AspGlu: 3.581 ± 0.493
1.953AspPhe: 1.953 ± 0.419
3.581AspGly: 3.581 ± 0.708
1.465AspHis: 1.465 ± 0.458
2.767AspIle: 2.767 ± 0.954
0.977AspLys: 0.977 ± 0.397
7.324AspLeu: 7.324 ± 0.919
0.488AspMet: 0.488 ± 0.367
0.651AspAsn: 0.651 ± 0.206
3.743AspPro: 3.743 ± 0.687
1.465AspGln: 1.465 ± 0.366
4.395AspArg: 4.395 ± 0.748
2.441AspSer: 2.441 ± 0.565
2.604AspThr: 2.604 ± 0.47
6.185AspVal: 6.185 ± 1.241
0.651AspTrp: 0.651 ± 0.305
0.651AspTyr: 0.651 ± 0.206
0.0AspXaa: 0.0 ± 0.0
Glu
6.51GluAla: 6.51 ± 1.132
0.326GluCys: 0.326 ± 0.2
3.418GluAsp: 3.418 ± 0.576
3.906GluGlu: 3.906 ± 1.005
2.116GluPhe: 2.116 ± 0.719
4.069GluGly: 4.069 ± 0.619
0.977GluHis: 0.977 ± 0.437
2.604GluIle: 2.604 ± 0.793
2.604GluLys: 2.604 ± 0.591
6.673GluLeu: 6.673 ± 1.084
1.79GluMet: 1.79 ± 0.562
1.465GluAsn: 1.465 ± 0.497
2.604GluPro: 2.604 ± 0.807
1.79GluGln: 1.79 ± 0.45
6.022GluArg: 6.022 ± 0.682
2.116GluSer: 2.116 ± 0.424
3.418GluThr: 3.418 ± 0.867
4.557GluVal: 4.557 ± 0.883
0.488GluTrp: 0.488 ± 0.285
1.465GluTyr: 1.465 ± 0.259
0.0GluXaa: 0.0 ± 0.0
Phe
2.279PheAla: 2.279 ± 0.852
0.488PheCys: 0.488 ± 0.274
1.79PheAsp: 1.79 ± 0.34
1.302PheGlu: 1.302 ± 0.406
1.465PhePhe: 1.465 ± 0.709
1.139PheGly: 1.139 ± 0.293
2.116PheHis: 2.116 ± 0.492
1.628PheIle: 1.628 ± 0.434
0.814PheLys: 0.814 ± 0.353
3.743PheLeu: 3.743 ± 0.889
0.651PheMet: 0.651 ± 0.362
0.977PheAsn: 0.977 ± 0.437
1.79PhePro: 1.79 ± 0.382
1.302PheGln: 1.302 ± 0.282
4.232PheArg: 4.232 ± 0.811
2.93PheSer: 2.93 ± 0.744
1.628PheThr: 1.628 ± 0.182
3.418PheVal: 3.418 ± 0.701
0.163PheTrp: 0.163 ± 0.175
0.814PheTyr: 0.814 ± 0.23
0.0PheXaa: 0.0 ± 0.0
Gly
7.324GlyAla: 7.324 ± 2.138
0.326GlyCys: 0.326 ± 0.192
3.581GlyAsp: 3.581 ± 0.963
2.116GlyGlu: 2.116 ± 0.546
1.953GlyPhe: 1.953 ± 0.605
3.906GlyGly: 3.906 ± 1.285
1.465GlyHis: 1.465 ± 0.284
1.953GlyIle: 1.953 ± 0.396
1.465GlyLys: 1.465 ± 0.564
4.232GlyLeu: 4.232 ± 0.722
1.628GlyMet: 1.628 ± 0.535
1.79GlyAsn: 1.79 ± 0.688
3.092GlyPro: 3.092 ± 0.556
2.116GlyGln: 2.116 ± 0.541
5.859GlyArg: 5.859 ± 0.668
3.092GlySer: 3.092 ± 0.607
3.581GlyThr: 3.581 ± 1.027
4.557GlyVal: 4.557 ± 0.791
0.977GlyTrp: 0.977 ± 0.369
1.953GlyTyr: 1.953 ± 0.521
0.0GlyXaa: 0.0 ± 0.0
His
3.092HisAla: 3.092 ± 0.494
0.651HisCys: 0.651 ± 0.378
1.953HisAsp: 1.953 ± 0.636
1.465HisGlu: 1.465 ± 0.436
0.488HisPhe: 0.488 ± 0.374
1.953HisGly: 1.953 ± 0.49
0.163HisHis: 0.163 ± 0.125
1.465HisIle: 1.465 ± 0.445
0.326HisLys: 0.326 ± 0.189
2.93HisLeu: 2.93 ± 0.586
0.488HisMet: 0.488 ± 0.249
0.488HisAsn: 0.488 ± 0.234
1.302HisPro: 1.302 ± 0.578
2.116HisGln: 2.116 ± 0.482
2.116HisArg: 2.116 ± 0.449
0.326HisSer: 0.326 ± 0.167
0.814HisThr: 0.814 ± 0.257
2.604HisVal: 2.604 ± 0.8
0.488HisTrp: 0.488 ± 0.205
0.488HisTyr: 0.488 ± 0.29
0.0HisXaa: 0.0 ± 0.0
Ile
4.557IleAla: 4.557 ± 1.123
1.139IleCys: 1.139 ± 0.519
2.604IleAsp: 2.604 ± 0.485
3.092IleGlu: 3.092 ± 0.741
1.953IlePhe: 1.953 ± 0.495
1.628IleGly: 1.628 ± 0.518
1.628IleHis: 1.628 ± 0.648
2.93IleIle: 2.93 ± 0.547
1.628IleLys: 1.628 ± 0.481
4.232IleLeu: 4.232 ± 1.082
0.651IleMet: 0.651 ± 0.266
0.814IleAsn: 0.814 ± 0.297
2.604IlePro: 2.604 ± 0.425
1.953IleGln: 1.953 ± 0.482
5.371IleArg: 5.371 ± 0.767
3.418IleSer: 3.418 ± 0.723
3.255IleThr: 3.255 ± 0.507
3.906IleVal: 3.906 ± 0.53
0.651IleTrp: 0.651 ± 0.266
2.279IleTyr: 2.279 ± 0.454
0.0IleXaa: 0.0 ± 0.0
Lys
2.767LysAla: 2.767 ± 0.835
1.139LysCys: 1.139 ± 0.54
2.279LysAsp: 2.279 ± 0.992
1.628LysGlu: 1.628 ± 0.499
1.302LysPhe: 1.302 ± 0.31
0.488LysGly: 0.488 ± 0.25
0.977LysHis: 0.977 ± 0.383
0.977LysIle: 0.977 ± 0.295
2.441LysLys: 2.441 ± 0.883
1.465LysLeu: 1.465 ± 0.564
0.488LysMet: 0.488 ± 0.203
1.628LysAsn: 1.628 ± 0.597
0.977LysPro: 0.977 ± 0.54
0.651LysGln: 0.651 ± 0.287
1.79LysArg: 1.79 ± 0.755
2.279LysSer: 2.279 ± 0.589
1.953LysThr: 1.953 ± 0.694
1.79LysVal: 1.79 ± 0.502
0.488LysTrp: 0.488 ± 0.309
0.488LysTyr: 0.488 ± 0.275
0.0LysXaa: 0.0 ± 0.0
Leu
8.138LeuAla: 8.138 ± 1.118
1.628LeuCys: 1.628 ± 0.498
5.208LeuAsp: 5.208 ± 1.108
4.395LeuGlu: 4.395 ± 0.832
4.069LeuPhe: 4.069 ± 0.734
5.371LeuGly: 5.371 ± 0.891
3.092LeuHis: 3.092 ± 0.466
4.395LeuIle: 4.395 ± 0.737
2.767LeuLys: 2.767 ± 0.662
8.138LeuLeu: 8.138 ± 1.346
2.441LeuMet: 2.441 ± 0.525
2.767LeuAsn: 2.767 ± 0.602
7.812LeuPro: 7.812 ± 0.798
3.743LeuGln: 3.743 ± 1.179
9.603LeuArg: 9.603 ± 1.459
5.534LeuSer: 5.534 ± 1.229
6.999LeuThr: 6.999 ± 1.023
6.51LeuVal: 6.51 ± 1.59
0.977LeuTrp: 0.977 ± 0.358
1.953LeuTyr: 1.953 ± 0.592
0.0LeuXaa: 0.0 ± 0.0
Met
2.767MetAla: 2.767 ± 0.782
0.651MetCys: 0.651 ± 0.25
0.977MetAsp: 0.977 ± 0.338
1.139MetGlu: 1.139 ± 0.366
0.814MetPhe: 0.814 ± 0.325
1.302MetGly: 1.302 ± 0.443
0.651MetHis: 0.651 ± 0.262
1.465MetIle: 1.465 ± 0.444
0.326MetLys: 0.326 ± 0.21
2.604MetLeu: 2.604 ± 0.517
0.977MetMet: 0.977 ± 0.34
0.326MetAsn: 0.326 ± 0.172
0.977MetPro: 0.977 ± 0.511
0.651MetGln: 0.651 ± 0.308
3.255MetArg: 3.255 ± 0.555
1.953MetSer: 1.953 ± 0.483
0.651MetThr: 0.651 ± 0.241
1.79MetVal: 1.79 ± 0.354
0.163MetTrp: 0.163 ± 0.139
1.139MetTyr: 1.139 ± 0.385
0.0MetXaa: 0.0 ± 0.0
Asn
3.906AsnAla: 3.906 ± 0.479
0.0AsnCys: 0.0 ± 0.0
1.139AsnAsp: 1.139 ± 0.393
2.116AsnGlu: 2.116 ± 0.575
1.302AsnPhe: 1.302 ± 0.385
2.279AsnGly: 2.279 ± 0.761
0.814AsnHis: 0.814 ± 0.312
1.465AsnIle: 1.465 ± 0.485
0.651AsnLys: 0.651 ± 0.405
2.279AsnLeu: 2.279 ± 0.608
0.326AsnMet: 0.326 ± 0.252
0.163AsnAsn: 0.163 ± 0.189
1.628AsnPro: 1.628 ± 0.661
0.814AsnGln: 0.814 ± 0.393
1.302AsnArg: 1.302 ± 0.39
0.814AsnSer: 0.814 ± 0.23
1.953AsnThr: 1.953 ± 0.368
2.116AsnVal: 2.116 ± 0.32
0.163AsnTrp: 0.163 ± 0.189
0.651AsnTyr: 0.651 ± 0.284
0.0AsnXaa: 0.0 ± 0.0
Pro
5.208ProAla: 5.208 ± 0.836
0.326ProCys: 0.326 ± 0.204
2.767ProAsp: 2.767 ± 0.444
4.883ProGlu: 4.883 ± 0.642
1.79ProPhe: 1.79 ± 0.762
3.743ProGly: 3.743 ± 1.095
1.79ProHis: 1.79 ± 0.378
2.279ProIle: 2.279 ± 0.527
1.139ProLys: 1.139 ± 0.445
4.557ProLeu: 4.557 ± 1.026
2.116ProMet: 2.116 ± 0.521
2.279ProAsn: 2.279 ± 0.821
6.185ProPro: 6.185 ± 1.892
2.116ProGln: 2.116 ± 0.411
5.046ProArg: 5.046 ± 0.709
3.092ProSer: 3.092 ± 0.746
5.859ProThr: 5.859 ± 0.657
3.255ProVal: 3.255 ± 0.67
0.651ProTrp: 0.651 ± 0.295
2.441ProTyr: 2.441 ± 0.692
0.0ProXaa: 0.0 ± 0.0
Gln
4.069GlnAla: 4.069 ± 0.979
0.326GlnCys: 0.326 ± 0.164
2.116GlnAsp: 2.116 ± 0.467
1.628GlnGlu: 1.628 ± 0.468
1.139GlnPhe: 1.139 ± 0.354
0.977GlnGly: 0.977 ± 0.26
0.977GlnHis: 0.977 ± 0.252
2.93GlnIle: 2.93 ± 0.743
1.139GlnLys: 1.139 ± 0.349
3.092GlnLeu: 3.092 ± 0.562
0.977GlnMet: 0.977 ± 0.467
2.116GlnAsn: 2.116 ± 0.321
1.628GlnPro: 1.628 ± 0.441
0.651GlnGln: 0.651 ± 0.354
4.069GlnArg: 4.069 ± 0.649
1.465GlnSer: 1.465 ± 0.338
2.767GlnThr: 2.767 ± 0.801
2.441GlnVal: 2.441 ± 0.586
0.163GlnTrp: 0.163 ± 0.145
0.488GlnTyr: 0.488 ± 0.256
0.0GlnXaa: 0.0 ± 0.0
Arg
8.464ArgAla: 8.464 ± 1.224
1.465ArgCys: 1.465 ± 0.466
5.859ArgAsp: 5.859 ± 0.895
6.185ArgGlu: 6.185 ± 0.713
3.906ArgPhe: 3.906 ± 0.966
6.348ArgGly: 6.348 ± 0.643
1.465ArgHis: 1.465 ± 0.486
4.883ArgIle: 4.883 ± 0.609
1.628ArgLys: 1.628 ± 0.378
9.603ArgLeu: 9.603 ± 1.503
3.418ArgMet: 3.418 ± 0.68
2.93ArgAsn: 2.93 ± 0.512
4.883ArgPro: 4.883 ± 0.652
2.279ArgGln: 2.279 ± 0.42
8.626ArgArg: 8.626 ± 1.79
4.069ArgSer: 4.069 ± 0.907
5.534ArgThr: 5.534 ± 0.873
8.952ArgVal: 8.952 ± 1.136
0.977ArgTrp: 0.977 ± 0.329
2.441ArgTyr: 2.441 ± 0.548
0.0ArgXaa: 0.0 ± 0.0
Ser
5.371SerAla: 5.371 ± 0.681
0.651SerCys: 0.651 ± 0.349
3.092SerAsp: 3.092 ± 0.444
3.906SerGlu: 3.906 ± 1.114
2.93SerPhe: 2.93 ± 0.635
3.743SerGly: 3.743 ± 0.475
0.814SerHis: 0.814 ± 0.253
3.418SerIle: 3.418 ± 0.627
1.302SerLys: 1.302 ± 0.551
4.72SerLeu: 4.72 ± 1.227
1.139SerMet: 1.139 ± 0.239
0.326SerAsn: 0.326 ± 0.164
3.255SerPro: 3.255 ± 0.649
1.139SerGln: 1.139 ± 0.412
5.534SerArg: 5.534 ± 0.773
4.395SerSer: 4.395 ± 0.981
4.557SerThr: 4.557 ± 1.125
3.255SerVal: 3.255 ± 0.725
0.977SerTrp: 0.977 ± 0.465
2.116SerTyr: 2.116 ± 0.396
0.0SerXaa: 0.0 ± 0.0
Thr
7.324ThrAla: 7.324 ± 0.934
0.814ThrCys: 0.814 ± 0.376
2.116ThrAsp: 2.116 ± 0.408
3.743ThrGlu: 3.743 ± 0.918
1.139ThrPhe: 1.139 ± 0.385
4.069ThrGly: 4.069 ± 0.879
1.628ThrHis: 1.628 ± 0.578
3.255ThrIle: 3.255 ± 0.704
1.302ThrLys: 1.302 ± 0.499
7.161ThrLeu: 7.161 ± 0.916
0.651ThrMet: 0.651 ± 0.246
1.628ThrAsn: 1.628 ± 0.463
4.069ThrPro: 4.069 ± 0.845
2.279ThrGln: 2.279 ± 0.781
6.999ThrArg: 6.999 ± 1.021
4.395ThrSer: 4.395 ± 0.954
3.906ThrThr: 3.906 ± 0.848
4.395ThrVal: 4.395 ± 0.609
0.977ThrTrp: 0.977 ± 0.288
1.79ThrTyr: 1.79 ± 0.371
0.0ThrXaa: 0.0 ± 0.0
Val
8.464ValAla: 8.464 ± 1.75
0.977ValCys: 0.977 ± 0.549
3.906ValAsp: 3.906 ± 0.439
5.208ValGlu: 5.208 ± 0.536
1.628ValPhe: 1.628 ± 0.396
3.743ValGly: 3.743 ± 0.574
1.79ValHis: 1.79 ± 0.366
3.906ValIle: 3.906 ± 0.565
2.279ValLys: 2.279 ± 0.707
7.975ValLeu: 7.975 ± 0.663
1.953ValMet: 1.953 ± 0.447
1.953ValAsn: 1.953 ± 0.509
5.697ValPro: 5.697 ± 0.571
3.906ValGln: 3.906 ± 0.684
5.534ValArg: 5.534 ± 0.864
4.883ValSer: 4.883 ± 0.688
5.046ValThr: 5.046 ± 0.72
4.232ValVal: 4.232 ± 0.601
0.814ValTrp: 0.814 ± 0.202
2.93ValTyr: 2.93 ± 0.686
0.0ValXaa: 0.0 ± 0.0
Trp
0.814TrpAla: 0.814 ± 0.301
0.163TrpCys: 0.163 ± 0.139
0.326TrpAsp: 0.326 ± 0.164
0.651TrpGlu: 0.651 ± 0.227
0.488TrpPhe: 0.488 ± 0.299
0.814TrpGly: 0.814 ± 0.312
0.326TrpHis: 0.326 ± 0.224
0.326TrpIle: 0.326 ± 0.166
0.977TrpLys: 0.977 ± 0.367
1.302TrpLeu: 1.302 ± 0.545
0.0TrpMet: 0.0 ± 0.0
0.814TrpAsn: 0.814 ± 0.401
0.326TrpPro: 0.326 ± 0.228
0.326TrpGln: 0.326 ± 0.252
1.139TrpArg: 1.139 ± 0.535
0.651TrpSer: 0.651 ± 0.281
0.651TrpThr: 0.651 ± 0.327
0.814TrpVal: 0.814 ± 0.277
0.163TrpTrp: 0.163 ± 0.175
0.488TrpTyr: 0.488 ± 0.257
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.255TyrAla: 3.255 ± 0.63
0.163TyrCys: 0.163 ± 0.189
1.465TyrAsp: 1.465 ± 0.402
1.465TyrGlu: 1.465 ± 0.58
0.814TyrPhe: 0.814 ± 0.331
2.604TyrGly: 2.604 ± 0.751
0.488TyrHis: 0.488 ± 0.206
1.302TyrIle: 1.302 ± 0.54
0.814TyrLys: 0.814 ± 0.341
2.279TyrLeu: 2.279 ± 0.513
0.488TyrMet: 0.488 ± 0.309
0.488TyrAsn: 0.488 ± 0.257
1.465TyrPro: 1.465 ± 0.637
1.465TyrGln: 1.465 ± 0.413
2.441TyrArg: 2.441 ± 0.537
1.953TyrSer: 1.953 ± 0.62
1.953TyrThr: 1.953 ± 0.439
2.767TyrVal: 2.767 ± 0.424
0.326TyrTrp: 0.326 ± 0.222
0.977TyrTyr: 0.977 ± 0.313
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (6145 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski