Amino acid dipepetide frequency for Mesorhizobium amorphae CCBAU 01583

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.097AlaAla: 16.097 ± 0.224	1.549AlaCys: 1.549 ± 0.049	6.576AlaAsp: 6.576 ± 0.101	6.967AlaGlu: 6.967 ± 0.113	4.194AlaPhe: 4.194 ± 0.077	10.378AlaGly: 10.378 ± 0.143	2.065AlaHis: 2.065 ± 0.06	6.01AlaIle: 6.01 ± 0.094	4.359AlaLys: 4.359 ± 0.082	11.221AlaLeu: 11.221 ± 0.15	3.426AlaMet: 3.426 ± 0.082	3.006AlaAsn: 3.006 ± 0.063	5.567AlaPro: 5.567 ± 0.105	3.337AlaGln: 3.337 ± 0.077	9.619AlaArg: 9.619 ± 0.134	7.904AlaSer: 7.904 ± 0.122	6.343AlaThr: 6.343 ± 0.112	7.893AlaVal: 7.893 ± 0.115	1.572AlaTrp: 1.572 ± 0.054	2.262AlaTyr: 2.262 ± 0.061	0.0AlaXaa: 0.0 ± 0.0
Cys	1.396CysAla: 1.396 ± 0.045	0.44CysCys: 0.44 ± 0.026	0.573CysAsp: 0.573 ± 0.033	0.501CysGlu: 0.501 ± 0.029	0.466CysPhe: 0.466 ± 0.029	1.124CysGly: 1.124 ± 0.04	0.309CysHis: 0.309 ± 0.021	0.438CysIle: 0.438 ± 0.027	0.275CysLys: 0.275 ± 0.021	1.084CysLeu: 1.084 ± 0.046	0.345CysMet: 0.345 ± 0.025	0.246CysAsn: 0.246 ± 0.018	0.745CysPro: 0.745 ± 0.036	0.338CysGln: 0.338 ± 0.021	1.791CysArg: 1.791 ± 0.051	1.242CysSer: 1.242 ± 0.045	0.57CysThr: 0.57 ± 0.034	0.635CysVal: 0.635 ± 0.034	0.316CysTrp: 0.316 ± 0.023	0.195CysTyr: 0.195 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.36AspAla: 6.36 ± 0.105	0.577AspCys: 0.577 ± 0.031	3.386AspAsp: 3.386 ± 0.083	3.427AspGlu: 3.427 ± 0.084	2.184AspPhe: 2.184 ± 0.061	5.187AspGly: 5.187 ± 0.1	1.292AspHis: 1.292 ± 0.051	2.989AspIle: 2.989 ± 0.067	1.866AspLys: 1.866 ± 0.055	5.399AspLeu: 5.399 ± 0.095	1.271AspMet: 1.271 ± 0.044	1.405AspAsn: 1.405 ± 0.052	3.087AspPro: 3.087 ± 0.076	1.964AspGln: 1.964 ± 0.056	4.686AspArg: 4.686 ± 0.087	2.176AspSer: 2.176 ± 0.063	2.57AspThr: 2.57 ± 0.064	3.87AspVal: 3.87 ± 0.085	0.935AspTrp: 0.935 ± 0.038	1.289AspTyr: 1.289 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	6.815GluAla: 6.815 ± 0.102	0.452GluCys: 0.452 ± 0.028	2.67GluAsp: 2.67 ± 0.077	2.888GluGlu: 2.888 ± 0.07	1.865GluPhe: 1.865 ± 0.059	3.679GluGly: 3.679 ± 0.082	1.191GluHis: 1.191 ± 0.042	3.401GluIle: 3.401 ± 0.08	2.467GluLys: 2.467 ± 0.056	4.997GluLeu: 4.997 ± 0.085	1.41GluMet: 1.41 ± 0.047	1.51GluAsn: 1.51 ± 0.044	2.624GluPro: 2.624 ± 0.076	2.021GluGln: 2.021 ± 0.061	4.831GluArg: 4.831 ± 0.093	2.372GluSer: 2.372 ± 0.06	3.068GluThr: 3.068 ± 0.059	3.398GluVal: 3.398 ± 0.074	0.724GluTrp: 0.724 ± 0.036	0.964GluTyr: 0.964 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	4.365PheAla: 4.365 ± 0.097	0.484PheCys: 0.484 ± 0.029	2.592PheAsp: 2.592 ± 0.064	2.126PheGlu: 2.126 ± 0.054	1.355PhePhe: 1.355 ± 0.046	3.444PheGly: 3.444 ± 0.076	0.706PheHis: 0.706 ± 0.034	1.539PheIle: 1.539 ± 0.05	1.013PheLys: 1.013 ± 0.041	3.059PheLeu: 3.059 ± 0.07	0.758PheMet: 0.758 ± 0.035	0.973PheAsn: 0.973 ± 0.034	1.605PhePro: 1.605 ± 0.05	1.142PheGln: 1.142 ± 0.042	2.532PheArg: 2.532 ± 0.061	2.483PheSer: 2.483 ± 0.056	1.74PheThr: 1.74 ± 0.043	2.584PheVal: 2.584 ± 0.058	0.509PheTrp: 0.509 ± 0.028	0.787PheTyr: 0.787 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	8.269GlyAla: 8.269 ± 0.117	1.04GlyCys: 1.04 ± 0.035	4.539GlyAsp: 4.539 ± 0.081	4.483GlyGlu: 4.483 ± 0.082	3.285GlyPhe: 3.285 ± 0.076	6.431GlyGly: 6.431 ± 0.12	1.798GlyHis: 1.798 ± 0.055	4.072GlyIle: 4.072 ± 0.08	3.61GlyLys: 3.61 ± 0.083	7.506GlyLeu: 7.506 ± 0.095	2.231GlyMet: 2.231 ± 0.05	2.276GlyAsn: 2.276 ± 0.066	3.239GlyPro: 3.239 ± 0.079	2.83GlyGln: 2.83 ± 0.078	6.376GlyArg: 6.376 ± 0.11	5.096GlySer: 5.096 ± 0.085	4.541GlyThr: 4.541 ± 0.082	5.119GlyVal: 5.119 ± 0.097	1.307GlyTrp: 1.307 ± 0.048	1.869GlyTyr: 1.869 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.207HisAla: 2.207 ± 0.06	0.279HisCys: 0.279 ± 0.022	1.291HisAsp: 1.291 ± 0.046	1.013HisGlu: 1.013 ± 0.039	0.831HisPhe: 0.831 ± 0.032	1.853HisGly: 1.853 ± 0.06	0.612HisHis: 0.612 ± 0.035	0.86HisIle: 0.86 ± 0.034	0.522HisLys: 0.522 ± 0.031	1.886HisLeu: 1.886 ± 0.062	0.449HisMet: 0.449 ± 0.024	0.411HisAsn: 0.411 ± 0.026	1.271HisPro: 1.271 ± 0.043	0.744HisGln: 0.744 ± 0.036	1.853HisArg: 1.853 ± 0.054	1.058HisSer: 1.058 ± 0.042	0.75HisThr: 0.75 ± 0.033	1.471HisVal: 1.471 ± 0.048	0.348HisTrp: 0.348 ± 0.022	0.527HisTyr: 0.527 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.618IleAla: 6.618 ± 0.096	0.66IleCys: 0.66 ± 0.035	3.623IleAsp: 3.623 ± 0.071	3.441IleGlu: 3.441 ± 0.07	1.593IlePhe: 1.593 ± 0.053	4.689IleGly: 4.689 ± 0.087	0.878IleHis: 0.878 ± 0.038	2.134IleIle: 2.134 ± 0.055	1.472IleLys: 1.472 ± 0.05	3.946IleLeu: 3.946 ± 0.087	1.022IleMet: 1.022 ± 0.041	1.263IleAsn: 1.263 ± 0.047	2.196IlePro: 2.196 ± 0.058	1.265IleGln: 1.265 ± 0.041	3.557IleArg: 3.557 ± 0.078	3.51IleSer: 3.51 ± 0.066	2.46IleThr: 2.46 ± 0.059	4.017IleVal: 4.017 ± 0.084	0.632IleTrp: 0.632 ± 0.031	0.97IleTyr: 0.97 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.658LysAla: 4.658 ± 0.087	0.321LysCys: 0.321 ± 0.022	1.81LysAsp: 1.81 ± 0.059	1.678LysGlu: 1.678 ± 0.055	0.91LysPhe: 0.91 ± 0.036	2.647LysGly: 2.647 ± 0.06	0.675LysHis: 0.675 ± 0.036	1.866LysIle: 1.866 ± 0.048	1.556LysLys: 1.556 ± 0.055	3.578LysLeu: 3.578 ± 0.081	0.916LysMet: 0.916 ± 0.04	1.002LysAsn: 1.002 ± 0.042	2.379LysPro: 2.379 ± 0.062	1.182LysGln: 1.182 ± 0.04	2.78LysArg: 2.78 ± 0.066	2.303LysSer: 2.303 ± 0.064	2.182LysThr: 2.182 ± 0.062	2.45LysVal: 2.45 ± 0.066	0.447LysTrp: 0.447 ± 0.027	0.667LysTyr: 0.667 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	12.027LeuAla: 12.027 ± 0.156	0.988LeuCys: 0.988 ± 0.036	5.509LeuAsp: 5.509 ± 0.099	4.843LeuGlu: 4.843 ± 0.096	3.223LeuPhe: 3.223 ± 0.069	6.978LeuGly: 6.978 ± 0.099	1.747LeuHis: 1.747 ± 0.056	4.455LeuIle: 4.455 ± 0.082	3.643LeuLys: 3.643 ± 0.079	8.069LeuLeu: 8.069 ± 0.13	1.944LeuMet: 1.944 ± 0.052	2.343LeuAsn: 2.343 ± 0.066	5.318LeuPro: 5.318 ± 0.103	2.862LeuGln: 2.862 ± 0.074	6.607LeuArg: 6.607 ± 0.112	6.349LeuSer: 6.349 ± 0.099	4.886LeuThr: 4.886 ± 0.093	6.59LeuVal: 6.59 ± 0.114	1.039LeuTrp: 1.039 ± 0.042	1.738LeuTyr: 1.738 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	3.261MetAla: 3.261 ± 0.063	0.254MetCys: 0.254 ± 0.019	1.074MetAsp: 1.074 ± 0.045	1.126MetGlu: 1.126 ± 0.042	0.693MetPhe: 0.693 ± 0.034	1.588MetGly: 1.588 ± 0.046	0.506MetHis: 0.506 ± 0.031	1.316MetIle: 1.316 ± 0.05	1.145MetLys: 1.145 ± 0.043	2.506MetLeu: 2.506 ± 0.061	0.687MetMet: 0.687 ± 0.034	0.835MetAsn: 0.835 ± 0.036	1.857MetPro: 1.857 ± 0.055	0.872MetGln: 0.872 ± 0.035	2.294MetArg: 2.294 ± 0.057	1.901MetSer: 1.901 ± 0.054	1.86MetThr: 1.86 ± 0.052	1.672MetVal: 1.672 ± 0.052	0.24MetTrp: 0.24 ± 0.019	0.258MetTyr: 0.258 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	2.981AsnAla: 2.981 ± 0.067	0.344AsnCys: 0.344 ± 0.024	1.668AsnAsp: 1.668 ± 0.05	1.228AsnGlu: 1.228 ± 0.048	0.956AsnPhe: 0.956 ± 0.036	2.434AsnGly: 2.434 ± 0.07	0.512AsnHis: 0.512 ± 0.028	1.31AsnIle: 1.31 ± 0.042	0.773AsnLys: 0.773 ± 0.031	2.37AsnLeu: 2.37 ± 0.062	0.68AsnMet: 0.68 ± 0.029	0.719AsnAsn: 0.719 ± 0.036	1.691AsnPro: 1.691 ± 0.048	0.779AsnGln: 0.779 ± 0.033	2.008AsnArg: 2.008 ± 0.053	1.698AsnSer: 1.698 ± 0.051	1.304AsnThr: 1.304 ± 0.047	1.912AsnVal: 1.912 ± 0.058	0.463AsnTrp: 0.463 ± 0.026	0.586AsnTyr: 0.586 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	7.07ProAla: 7.07 ± 0.123	0.707ProCys: 0.707 ± 0.04	3.349ProAsp: 3.349 ± 0.07	2.987ProGlu: 2.987 ± 0.065	1.791ProPhe: 1.791 ± 0.048	4.241ProGly: 4.241 ± 0.072	0.99ProHis: 0.99 ± 0.038	2.46ProIle: 2.46 ± 0.059	1.909ProLys: 1.909 ± 0.057	4.353ProLeu: 4.353 ± 0.074	1.507ProMet: 1.507 ± 0.043	1.497ProAsn: 1.497 ± 0.047	3.125ProPro: 3.125 ± 0.083	1.584ProGln: 1.584 ± 0.05	4.038ProArg: 4.038 ± 0.084	4.029ProSer: 4.029 ± 0.09	3.093ProThr: 3.093 ± 0.079	3.882ProVal: 3.882 ± 0.09	0.738ProTrp: 0.738 ± 0.038	1.0ProTyr: 1.0 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	3.957GlnAla: 3.957 ± 0.09	0.331GlnCys: 0.331 ± 0.021	1.5GlnAsp: 1.5 ± 0.052	1.553GlnGlu: 1.553 ± 0.049	1.118GlnPhe: 1.118 ± 0.041	2.282GlnGly: 2.282 ± 0.063	0.759GlnHis: 0.759 ± 0.034	1.762GlnIle: 1.762 ± 0.05	1.228GlnLys: 1.228 ± 0.044	2.882GlnLeu: 2.882 ± 0.075	0.864GlnMet: 0.864 ± 0.037	0.91GlnAsn: 0.91 ± 0.039	2.102GlnPro: 2.102 ± 0.054	1.251GlnGln: 1.251 ± 0.053	2.967GlnArg: 2.967 ± 0.082	1.885GlnSer: 1.885 ± 0.063	1.663GlnThr: 1.663 ± 0.048	1.963GlnVal: 1.963 ± 0.056	0.38GlnTrp: 0.38 ± 0.025	0.6GlnTyr: 0.6 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	8.232ArgAla: 8.232 ± 0.122	1.549ArgCys: 1.549 ± 0.052	3.908ArgAsp: 3.908 ± 0.076	3.852ArgGlu: 3.852 ± 0.078	3.125ArgPhe: 3.125 ± 0.072	4.815ArgGly: 4.815 ± 0.104	2.201ArgHis: 2.201 ± 0.067	4.072ArgIle: 4.072 ± 0.08	2.948ArgLys: 2.948 ± 0.069	8.325ArgLeu: 8.325 ± 0.114	2.636ArgMet: 2.636 ± 0.062	2.189ArgAsn: 2.189 ± 0.06	4.822ArgPro: 4.822 ± 0.097	3.452ArgGln: 3.452 ± 0.085	9.191ArgArg: 9.191 ± 0.177	6.76ArgSer: 6.76 ± 0.129	4.069ArgThr: 4.069 ± 0.078	4.189ArgVal: 4.189 ± 0.081	1.471ArgTrp: 1.471 ± 0.051	1.613ArgTyr: 1.613 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	8.116SerAla: 8.116 ± 0.138	1.118SerCys: 1.118 ± 0.041	3.164SerAsp: 3.164 ± 0.075	2.81SerGlu: 2.81 ± 0.071	2.373SerPhe: 2.373 ± 0.06	5.817SerGly: 5.817 ± 0.094	1.119SerHis: 1.119 ± 0.039	3.255SerIle: 3.255 ± 0.073	2.016SerLys: 2.016 ± 0.05	5.361SerLeu: 5.361 ± 0.089	2.074SerMet: 2.074 ± 0.05	1.712SerAsn: 1.712 ± 0.057	4.159SerPro: 4.159 ± 0.091	1.704SerGln: 1.704 ± 0.052	5.972SerArg: 5.972 ± 0.117	5.703SerSer: 5.703 ± 0.141	4.324SerThr: 4.324 ± 0.098	4.096SerVal: 4.096 ± 0.08	1.051SerTrp: 1.051 ± 0.038	1.152SerTyr: 1.152 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	6.373ThrAla: 6.373 ± 0.106	0.739ThrCys: 0.739 ± 0.035	2.778ThrAsp: 2.778 ± 0.081	2.482ThrGlu: 2.482 ± 0.055	2.059ThrPhe: 2.059 ± 0.062	4.826ThrGly: 4.826 ± 0.09	0.869ThrHis: 0.869 ± 0.033	3.09ThrIle: 3.09 ± 0.06	1.718ThrLys: 1.718 ± 0.05	4.921ThrLeu: 4.921 ± 0.093	1.419ThrMet: 1.419 ± 0.048	1.378ThrAsn: 1.378 ± 0.039	3.25ThrPro: 3.25 ± 0.063	1.379ThrGln: 1.379 ± 0.052	3.982ThrArg: 3.982 ± 0.096	4.006ThrSer: 4.006 ± 0.083	3.129ThrThr: 3.129 ± 0.085	4.195ThrVal: 4.195 ± 0.098	0.75ThrTrp: 0.75 ± 0.031	1.081ThrTyr: 1.081 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	8.107ValAla: 8.107 ± 0.12	0.68ValCys: 0.68 ± 0.032	4.032ValAsp: 4.032 ± 0.079	4.264ValGlu: 4.264 ± 0.091	2.457ValPhe: 2.457 ± 0.063	5.104ValGly: 5.104 ± 0.094	1.262ValHis: 1.262 ± 0.045	3.473ValIle: 3.473 ± 0.078	2.245ValLys: 2.245 ± 0.058	6.346ValLeu: 6.346 ± 0.105	1.481ValMet: 1.481 ± 0.045	1.839ValAsn: 1.839 ± 0.064	3.366ValPro: 3.366 ± 0.073	2.01ValGln: 2.01 ± 0.051	4.973ValArg: 4.973 ± 0.095	4.279ValSer: 4.279 ± 0.091	4.131ValThr: 4.131 ± 0.093	4.967ValVal: 4.967 ± 0.094	0.724ValTrp: 0.724 ± 0.04	1.222ValTyr: 1.222 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	1.237TrpAla: 1.237 ± 0.047	0.258TrpCys: 0.258 ± 0.021	0.593TrpAsp: 0.593 ± 0.029	0.487TrpGlu: 0.487 ± 0.033	0.512TrpPhe: 0.512 ± 0.027	0.663TrpGly: 0.663 ± 0.035	0.374TrpHis: 0.374 ± 0.029	0.701TrpIle: 0.701 ± 0.027	0.6TrpLys: 0.6 ± 0.031	1.433TrpLeu: 1.433 ± 0.049	0.441TrpMet: 0.441 ± 0.025	0.428TrpAsn: 0.428 ± 0.028	1.11TrpPro: 1.11 ± 0.044	0.576TrpGln: 0.576 ± 0.031	1.587TrpArg: 1.587 ± 0.052	1.17TrpSer: 1.17 ± 0.047	0.811TrpThr: 0.811 ± 0.038	0.698TrpVal: 0.698 ± 0.03	0.24TrpTrp: 0.24 ± 0.019	0.286TrpTyr: 0.286 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.198TyrAla: 2.198 ± 0.055	0.26TyrCys: 0.26 ± 0.02	1.286TyrAsp: 1.286 ± 0.045	1.19TyrGlu: 1.19 ± 0.043	0.805TyrPhe: 0.805 ± 0.036	1.738TyrGly: 1.738 ± 0.056	0.371TyrHis: 0.371 ± 0.026	0.741TyrIle: 0.741 ± 0.031	0.645TyrLys: 0.645 ± 0.024	1.914TyrLeu: 1.914 ± 0.055	0.383TyrMet: 0.383 ± 0.023	0.477TyrAsn: 0.477 ± 0.029	0.838TyrPro: 0.838 ± 0.03	0.667TyrGln: 0.667 ± 0.033	1.775TyrArg: 1.775 ± 0.06	1.171TyrSer: 1.171 ± 0.046	0.93TyrThr: 0.93 ± 0.036	1.359TyrVal: 1.359 ± 0.05	0.319TyrTrp: 0.319 ± 0.023	0.467TyrTyr: 0.467 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4266 proteins (654768 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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