Amino acid dipepetide frequency for White bream virus (isolate Blicca bjoerkna L./Germany/DF24/00) (WBV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.222AlaAla: 3.222 ± 0.428
0.614AlaCys: 0.614 ± 0.565
2.072AlaAsp: 2.072 ± 0.296
2.302AlaGlu: 2.302 ± 0.44
3.453AlaPhe: 3.453 ± 0.282
2.225AlaGly: 2.225 ± 0.686
2.839AlaHis: 2.839 ± 0.693
4.91AlaIle: 4.91 ± 0.528
2.532AlaLys: 2.532 ± 0.6
4.68AlaLeu: 4.68 ± 0.608
1.151AlaMet: 1.151 ± 0.204
2.685AlaAsn: 2.685 ± 0.41
2.455AlaPro: 2.455 ± 0.499
3.759AlaGln: 3.759 ± 0.608
1.995AlaArg: 1.995 ± 0.402
7.826AlaSer: 7.826 ± 0.659
5.601AlaThr: 5.601 ± 0.516
3.913AlaVal: 3.913 ± 0.361
0.153AlaTrp: 0.153 ± 0.049
3.146AlaTyr: 3.146 ± 0.54
0.0AlaXaa: 0.0 ± 0.0
Cys
2.148CysAla: 2.148 ± 0.633
0.384CysCys: 0.384 ± 0.108
0.767CysAsp: 0.767 ± 0.567
0.384CysGlu: 0.384 ± 0.114
0.767CysPhe: 0.767 ± 0.571
0.997CysGly: 0.997 ± 0.371
0.691CysHis: 0.691 ± 0.471
1.304CysIle: 1.304 ± 0.322
0.537CysLys: 0.537 ± 0.159
1.458CysLeu: 1.458 ± 0.416
0.077CysMet: 0.077 ± 0.051
0.997CysAsn: 0.997 ± 0.39
1.151CysPro: 1.151 ± 0.291
0.844CysGln: 0.844 ± 0.192
0.537CysArg: 0.537 ± 0.228
1.151CysSer: 1.151 ± 1.03
2.225CysThr: 2.225 ± 0.513
1.381CysVal: 1.381 ± 0.298
0.23CysTrp: 0.23 ± 0.072
0.537CysTyr: 0.537 ± 0.176
0.0CysXaa: 0.0 ± 0.0
Asp
1.918AspAla: 1.918 ± 0.291
1.534AspCys: 1.534 ± 0.385
1.381AspAsp: 1.381 ± 0.408
1.611AspGlu: 1.611 ± 0.505
2.302AspPhe: 2.302 ± 0.297
1.688AspGly: 1.688 ± 0.264
0.767AspHis: 0.767 ± 0.355
3.222AspIle: 3.222 ± 0.535
1.841AspLys: 1.841 ± 0.817
3.836AspLeu: 3.836 ± 0.524
0.614AspMet: 0.614 ± 0.474
2.148AspAsn: 2.148 ± 0.295
2.225AspPro: 2.225 ± 0.482
1.918AspGln: 1.918 ± 0.803
0.844AspArg: 0.844 ± 0.254
3.759AspSer: 3.759 ± 0.478
4.527AspThr: 4.527 ± 0.579
1.304AspVal: 1.304 ± 0.985
0.23AspTrp: 0.23 ± 0.072
1.995AspTyr: 1.995 ± 0.4
0.0AspXaa: 0.0 ± 0.0
Glu
2.685GluAla: 2.685 ± 0.45
0.46GluCys: 0.46 ± 0.148
1.381GluAsp: 1.381 ± 0.433
3.069GluGlu: 3.069 ± 0.745
1.304GluPhe: 1.304 ± 0.347
1.765GluGly: 1.765 ± 0.552
1.304GluHis: 1.304 ± 0.255
2.839GluIle: 2.839 ± 0.425
1.304GluLys: 1.304 ± 1.454
3.529GluLeu: 3.529 ± 0.461
1.381GluMet: 1.381 ± 0.408
1.381GluAsn: 1.381 ± 0.408
2.762GluPro: 2.762 ± 0.696
2.378GluGln: 2.378 ± 0.454
1.304GluArg: 1.304 ± 0.401
3.529GluSer: 3.529 ± 0.827
5.14GluThr: 5.14 ± 0.715
2.609GluVal: 2.609 ± 0.401
0.537GluTrp: 0.537 ± 0.159
1.381GluTyr: 1.381 ± 0.433
0.0GluXaa: 0.0 ± 0.0
Phe
2.839PheAla: 2.839 ± 0.706
1.534PheCys: 1.534 ± 0.401
1.534PheAsp: 1.534 ± 0.541
1.228PheGlu: 1.228 ± 0.477
2.839PhePhe: 2.839 ± 0.271
1.995PheGly: 1.995 ± 0.381
1.995PheHis: 1.995 ± 0.374
4.296PheIle: 4.296 ± 0.591
1.534PheLys: 1.534 ± 0.323
4.45PheLeu: 4.45 ± 0.392
1.228PheMet: 1.228 ± 0.348
2.148PheAsn: 2.148 ± 0.357
1.688PhePro: 1.688 ± 0.361
2.072PheGln: 2.072 ± 0.421
0.691PheArg: 0.691 ± 0.105
3.836PheSer: 3.836 ± 0.361
4.45PheThr: 4.45 ± 0.758
3.99PheVal: 3.99 ± 0.781
0.307PheTrp: 0.307 ± 0.099
2.378PheTyr: 2.378 ± 0.697
0.0PheXaa: 0.0 ± 0.0
Gly
2.302GlyAla: 2.302 ± 0.28
0.767GlyCys: 0.767 ± 0.256
1.304GlyAsp: 1.304 ± 0.583
1.458GlyGlu: 1.458 ± 0.294
1.765GlyPhe: 1.765 ± 0.379
1.381GlyGly: 1.381 ± 1.038
1.534GlyHis: 1.534 ± 0.339
3.069GlyIle: 3.069 ± 0.392
2.225GlyLys: 2.225 ± 0.445
2.225GlyLeu: 2.225 ± 0.338
0.46GlyMet: 0.46 ± 0.489
2.148GlyAsn: 2.148 ± 0.361
1.074GlyPro: 1.074 ± 0.361
1.151GlyGln: 1.151 ± 0.338
1.151GlyArg: 1.151 ± 1.022
4.603GlySer: 4.603 ± 1.12
3.99GlyThr: 3.99 ± 0.486
1.151GlyVal: 1.151 ± 0.502
0.23GlyTrp: 0.23 ± 0.072
2.609GlyTyr: 2.609 ± 0.695
0.0GlyXaa: 0.0 ± 0.0
His
2.685HisAla: 2.685 ± 0.802
0.691HisCys: 0.691 ± 0.105
0.767HisAsp: 0.767 ± 0.39
0.997HisGlu: 0.997 ± 0.327
1.688HisPhe: 1.688 ± 0.287
1.381HisGly: 1.381 ± 0.402
1.074HisHis: 1.074 ± 0.369
2.225HisIle: 2.225 ± 0.396
2.378HisLys: 2.378 ± 0.609
4.296HisLeu: 4.296 ± 0.608
0.384HisMet: 0.384 ± 0.205
1.918HisAsn: 1.918 ± 0.446
1.151HisPro: 1.151 ± 0.212
0.997HisGln: 0.997 ± 0.402
0.537HisArg: 0.537 ± 0.429
1.458HisSer: 1.458 ± 0.236
3.299HisThr: 3.299 ± 0.596
1.458HisVal: 1.458 ± 0.471
0.384HisTrp: 0.384 ± 0.113
1.534HisTyr: 1.534 ± 0.316
0.0HisXaa: 0.0 ± 0.0
Ile
4.066IleAla: 4.066 ± 0.707
0.691IleCys: 0.691 ± 0.217
1.995IleAsp: 1.995 ± 0.447
2.609IleGlu: 2.609 ± 0.449
3.069IlePhe: 3.069 ± 0.45
3.222IleGly: 3.222 ± 0.582
1.151IleHis: 1.151 ± 0.44
3.606IleIle: 3.606 ± 1.492
3.913IleLys: 3.913 ± 0.675
7.442IleLeu: 7.442 ± 1.632
1.304IleMet: 1.304 ± 0.294
4.22IleAsn: 4.22 ± 0.419
4.066IlePro: 4.066 ± 1.138
4.143IleGln: 4.143 ± 0.62
1.765IleArg: 1.765 ± 0.299
5.14IleSer: 5.14 ± 0.273
7.826IleThr: 7.826 ± 0.902
3.529IleVal: 3.529 ± 0.313
0.23IleTrp: 0.23 ± 0.455
2.532IleTyr: 2.532 ± 0.367
0.0IleXaa: 0.0 ± 0.0
Lys
2.532LysAla: 2.532 ± 0.743
0.844LysCys: 0.844 ± 0.413
2.148LysAsp: 2.148 ± 0.878
2.455LysGlu: 2.455 ± 0.838
2.609LysPhe: 2.609 ± 0.448
2.225LysGly: 2.225 ± 0.401
2.072LysHis: 2.072 ± 0.47
2.072LysIle: 2.072 ± 0.503
1.841LysLys: 1.841 ± 0.509
5.754LysLeu: 5.754 ± 0.773
0.614LysMet: 0.614 ± 0.981
1.918LysAsn: 1.918 ± 0.319
4.296LysPro: 4.296 ± 0.791
2.148LysGln: 2.148 ± 0.373
1.304LysArg: 1.304 ± 0.412
3.069LysSer: 3.069 ± 1.891
4.834LysThr: 4.834 ± 0.298
4.066LysVal: 4.066 ± 0.791
0.0LysTrp: 0.0 ± 0.0
1.688LysTyr: 1.688 ± 0.389
0.0LysXaa: 0.0 ± 0.0
Leu
6.521LeuAla: 6.521 ± 0.655
2.072LeuCys: 2.072 ± 0.494
5.524LeuAsp: 5.524 ± 0.345
2.839LeuGlu: 2.839 ± 0.446
4.296LeuPhe: 4.296 ± 0.477
3.759LeuGly: 3.759 ± 0.924
3.376LeuHis: 3.376 ± 0.723
5.601LeuIle: 5.601 ± 0.655
4.68LeuLys: 4.68 ± 0.732
8.439LeuLeu: 8.439 ± 4.271
1.381LeuMet: 1.381 ± 0.57
6.138LeuAsn: 6.138 ± 1.721
5.14LeuPro: 5.14 ± 0.703
4.834LeuGln: 4.834 ± 1.202
2.609LeuArg: 2.609 ± 0.414
6.061LeuSer: 6.061 ± 1.302
11.201LeuThr: 11.201 ± 0.7
4.296LeuVal: 4.296 ± 1.44
0.46LeuTrp: 0.46 ± 0.09
3.529LeuTyr: 3.529 ± 0.589
0.0LeuXaa: 0.0 ± 0.0
Met
1.841MetAla: 1.841 ± 0.3
0.384MetCys: 0.384 ± 0.487
0.384MetAsp: 0.384 ± 0.113
0.614MetGlu: 0.614 ± 0.198
0.46MetPhe: 0.46 ± 0.423
0.307MetGly: 0.307 ± 0.203
0.537MetHis: 0.537 ± 0.098
0.844MetIle: 0.844 ± 0.517
0.997MetLys: 0.997 ± 0.231
1.995MetLeu: 1.995 ± 0.463
0.23MetMet: 0.23 ± 1.035
0.921MetAsn: 0.921 ± 0.157
1.074MetPro: 1.074 ± 0.926
0.997MetGln: 0.997 ± 0.169
0.921MetArg: 0.921 ± 0.207
1.458MetSer: 1.458 ± 1.56
0.691MetThr: 0.691 ± 0.105
1.074MetVal: 1.074 ± 0.858
0.384MetTrp: 0.384 ± 0.457
0.921MetTyr: 0.921 ± 0.441
0.0MetXaa: 0.0 ± 0.0
Asn
4.066AsnAla: 4.066 ± 0.47
0.46AsnCys: 0.46 ± 0.249
1.995AsnAsp: 1.995 ± 0.383
2.225AsnGlu: 2.225 ± 0.338
2.532AsnPhe: 2.532 ± 0.611
1.918AsnGly: 1.918 ± 0.954
2.225AsnHis: 2.225 ± 0.634
4.296AsnIle: 4.296 ± 0.538
3.606AsnLys: 3.606 ± 0.67
4.373AsnLeu: 4.373 ± 1.622
0.921AsnMet: 0.921 ± 0.163
4.68AsnAsn: 4.68 ± 0.709
2.532AsnPro: 2.532 ± 0.419
2.072AsnGln: 2.072 ± 1.031
1.074AsnArg: 1.074 ± 0.462
2.532AsnSer: 2.532 ± 0.687
6.061AsnThr: 6.061 ± 0.228
3.453AsnVal: 3.453 ± 0.301
0.614AsnTrp: 0.614 ± 0.198
1.765AsnTyr: 1.765 ± 0.516
0.0AsnXaa: 0.0 ± 0.0
Pro
2.915ProAla: 2.915 ± 0.43
1.074ProCys: 1.074 ± 0.206
2.609ProAsp: 2.609 ± 0.446
3.529ProGlu: 3.529 ± 0.94
2.378ProPhe: 2.378 ± 0.271
1.228ProGly: 1.228 ± 0.257
0.997ProHis: 0.997 ± 0.327
4.45ProIle: 4.45 ± 0.714
3.529ProLys: 3.529 ± 0.672
6.215ProLeu: 6.215 ± 0.987
0.614ProMet: 0.614 ± 0.686
2.839ProAsn: 2.839 ± 0.749
3.069ProPro: 3.069 ± 0.711
1.688ProGln: 1.688 ± 1.033
1.151ProArg: 1.151 ± 0.936
5.14ProSer: 5.14 ± 0.483
9.744ProThr: 9.744 ± 1.13
4.143ProVal: 4.143 ± 0.62
0.614ProTrp: 0.614 ± 0.097
2.455ProTyr: 2.455 ± 0.387
0.0ProXaa: 0.0 ± 0.0
Gln
2.915GlnAla: 2.915 ± 0.456
0.921GlnCys: 0.921 ± 0.476
1.841GlnAsp: 1.841 ± 0.408
1.611GlnGlu: 1.611 ± 0.434
1.611GlnPhe: 1.611 ± 0.624
1.381GlnGly: 1.381 ± 0.36
1.688GlnHis: 1.688 ± 0.496
2.609GlnIle: 2.609 ± 0.642
1.841GlnLys: 1.841 ± 0.372
4.987GlnLeu: 4.987 ± 0.865
0.384GlnMet: 0.384 ± 0.113
2.532GlnAsn: 2.532 ± 0.387
3.99GlnPro: 3.99 ± 1.027
4.143GlnGln: 4.143 ± 1.21
1.458GlnArg: 1.458 ± 0.458
4.066GlnSer: 4.066 ± 1.017
6.521GlnThr: 6.521 ± 1.096
3.222GlnVal: 3.222 ± 0.63
0.46GlnTrp: 0.46 ± 0.148
1.381GlnTyr: 1.381 ± 0.342
0.0GlnXaa: 0.0 ± 0.0
Arg
1.074ArgAla: 1.074 ± 0.621
0.384ArgCys: 0.384 ± 0.113
0.691ArgAsp: 0.691 ± 0.205
0.767ArgGlu: 0.767 ± 0.134
1.074ArgPhe: 1.074 ± 0.206
0.384ArgGly: 0.384 ± 0.457
0.537ArgHis: 0.537 ± 0.185
1.304ArgIle: 1.304 ± 0.383
1.841ArgLys: 1.841 ± 0.382
1.995ArgLeu: 1.995 ± 0.299
0.921ArgMet: 0.921 ± 0.454
1.841ArgAsn: 1.841 ± 0.982
1.534ArgPro: 1.534 ± 0.402
2.302ArgGln: 2.302 ± 0.588
1.765ArgArg: 1.765 ± 0.403
1.841ArgSer: 1.841 ± 0.563
2.992ArgThr: 2.992 ± 0.587
1.381ArgVal: 1.381 ± 0.44
0.077ArgTrp: 0.077 ± 0.156
1.688ArgTyr: 1.688 ± 0.367
0.0ArgXaa: 0.0 ± 0.0
Ser
4.757SerAla: 4.757 ± 1.669
1.381SerCys: 1.381 ± 0.809
4.45SerAsp: 4.45 ± 0.448
4.296SerGlu: 4.296 ± 0.878
3.99SerPhe: 3.99 ± 0.578
2.302SerGly: 2.302 ± 0.839
1.534SerHis: 1.534 ± 0.444
4.373SerIle: 4.373 ± 0.522
3.529SerLys: 3.529 ± 1.289
6.675SerLeu: 6.675 ± 1.112
1.304SerMet: 1.304 ± 0.224
4.066SerAsn: 4.066 ± 0.545
4.834SerPro: 4.834 ± 0.752
3.529SerGln: 3.529 ± 0.631
1.611SerArg: 1.611 ± 0.267
6.061SerSer: 6.061 ± 0.571
8.286SerThr: 8.286 ± 0.755
5.601SerVal: 5.601 ± 1.464
0.767SerTrp: 0.767 ± 0.355
3.453SerTyr: 3.453 ± 0.632
0.0SerXaa: 0.0 ± 0.0
Thr
6.675ThrAla: 6.675 ± 1.032
2.225ThrCys: 2.225 ± 0.359
4.373ThrAsp: 4.373 ± 0.77
5.677ThrGlu: 5.677 ± 0.766
6.828ThrPhe: 6.828 ± 1.087
4.373ThrGly: 4.373 ± 0.561
4.22ThrHis: 4.22 ± 0.669
7.902ThrIle: 7.902 ± 0.8
3.683ThrLys: 3.683 ± 1.339
10.588ThrLeu: 10.588 ± 0.975
1.841ThrMet: 1.841 ± 0.71
4.987ThrAsn: 4.987 ± 0.831
11.201ThrPro: 11.201 ± 2.101
4.143ThrGln: 4.143 ± 0.66
2.225ThrArg: 2.225 ± 0.479
8.209ThrSer: 8.209 ± 0.573
15.805ThrThr: 15.805 ± 1.387
8.133ThrVal: 8.133 ± 0.849
0.46ThrTrp: 0.46 ± 0.09
4.91ThrTyr: 4.91 ± 0.9
0.0ThrXaa: 0.0 ± 0.0
Val
3.606ValAla: 3.606 ± 1.023
1.381ValCys: 1.381 ± 0.344
2.455ValAsp: 2.455 ± 1.097
2.455ValGlu: 2.455 ± 0.473
2.455ValPhe: 2.455 ± 0.284
2.378ValGly: 2.378 ± 0.731
1.304ValHis: 1.304 ± 0.418
2.992ValIle: 2.992 ± 1.148
3.913ValLys: 3.913 ± 0.485
5.294ValLeu: 5.294 ± 0.608
1.228ValMet: 1.228 ± 0.351
2.455ValAsn: 2.455 ± 0.896
3.299ValPro: 3.299 ± 0.536
3.913ValGln: 3.913 ± 0.877
1.918ValArg: 1.918 ± 0.648
3.99ValSer: 3.99 ± 0.962
8.67ValThr: 8.67 ± 1.162
4.68ValVal: 4.68 ± 0.731
0.23ValTrp: 0.23 ± 0.072
3.529ValTyr: 3.529 ± 1.203
0.0ValXaa: 0.0 ± 0.0
Trp
0.307TrpAla: 0.307 ± 0.44
0.307TrpCys: 0.307 ± 0.099
0.23TrpAsp: 0.23 ± 0.152
0.0TrpGlu: 0.0 ± 0.0
0.307TrpPhe: 0.307 ± 0.44
0.077TrpGly: 0.077 ± 0.069
0.0TrpHis: 0.0 ± 0.0
0.23TrpIle: 0.23 ± 0.125
0.384TrpLys: 0.384 ± 0.198
0.767TrpLeu: 0.767 ± 0.216
0.153TrpMet: 0.153 ± 0.049
0.23TrpAsn: 0.23 ± 0.072
0.307TrpPro: 0.307 ± 0.115
0.23TrpGln: 0.23 ± 0.125
0.307TrpArg: 0.307 ± 0.099
0.384TrpSer: 0.384 ± 0.113
0.921TrpThr: 0.921 ± 0.163
0.614TrpVal: 0.614 ± 0.216
0.077TrpTrp: 0.077 ± 0.069
0.614TrpTyr: 0.614 ± 0.198
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.455TyrAla: 2.455 ± 0.457
0.46TyrCys: 0.46 ± 0.249
1.765TyrAsp: 1.765 ± 0.707
1.918TyrGlu: 1.918 ± 0.329
1.304TyrPhe: 1.304 ± 0.298
1.611TyrGly: 1.611 ± 0.324
1.534TyrHis: 1.534 ± 0.377
4.373TyrIle: 4.373 ± 0.51
2.378TyrLys: 2.378 ± 0.338
3.759TyrLeu: 3.759 ± 0.625
0.767TyrMet: 0.767 ± 0.212
3.146TyrAsn: 3.146 ± 0.575
2.532TyrPro: 2.532 ± 0.417
2.302TyrGln: 2.302 ± 0.578
1.228TyrArg: 1.228 ± 0.373
2.685TyrSer: 2.685 ± 0.517
5.677TyrThr: 5.677 ± 0.584
2.148TyrVal: 2.148 ± 0.49
0.0TyrTrp: 0.0 ± 0.0
2.839TyrTyr: 2.839 ± 0.892
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (13035 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski