Strongyloides venezuelensis (Threadworm)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae; Strongyloides

Average proteome isoelectric point is 7.09

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 16626 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0K0FCV0|A0A0K0FCV0_STRVS Integrase catalytic domain-containing protein OS=Strongyloides venezuelensis OX=75913 PE=4 SV=1
MM1 pKa = 7.38LHH3 pKa = 6.66EE4 pKa = 4.86EE5 pKa = 4.21EE6 pKa = 5.49NDD8 pKa = 3.74TFDD11 pKa = 4.02EE12 pKa = 4.38STKK15 pKa = 10.47YY16 pKa = 10.39KK17 pKa = 10.19HH18 pKa = 7.02DD19 pKa = 4.06PASYY23 pKa = 10.49EE24 pKa = 3.79LTKK27 pKa = 10.95YY28 pKa = 10.43ISLSLCTSYY37 pKa = 11.77VNDD40 pKa = 3.55VLNLFVDD47 pKa = 4.33YY48 pKa = 10.86EE49 pKa = 4.69DD50 pKa = 5.68KK51 pKa = 11.56NDD53 pKa = 3.99MDD55 pKa = 4.45NGDD58 pKa = 4.16PVSDD62 pKa = 4.17FLPIINLLNMVFNN75 pKa = 5.04

Molecular weight: 8.74 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0K0FXN1|A0A0K0FXN1_STRVS C2H2-type domain-containing protein OS=Strongyloides venezuelensis OX=75913 PE=4 SV=1
XX1 pKa = 7.98RR2 pKa = 11.84KK3 pKa = 7.31PTTRR7 pKa = 11.84KK8 pKa = 8.42LTTRR12 pKa = 11.84RR13 pKa = 11.84PTTRR17 pKa = 11.84RR18 pKa = 11.84PTTTKK23 pKa = 8.83PTTRR27 pKa = 11.84KK28 pKa = 7.82PTTTKK33 pKa = 9.4PTTTTTKK40 pKa = 9.37PTTTTMM46 pKa = 3.63

Molecular weight: 5.13 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

16597

29

16626

6663319

7

8239

400.8

45.86

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.027 ± 0.017

2.08 ± 0.015

5.511 ± 0.016

6.508 ± 0.027

4.934 ± 0.017

4.752 ± 0.022

2.038 ± 0.008

8.128 ± 0.023

8.444 ± 0.022

8.73 ± 0.022

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.276 ± 0.009

7.223 ± 0.021

3.849 ± 0.018

3.292 ± 0.014

4.158 ± 0.013

8.111 ± 0.023

5.578 ± 0.02

5.386 ± 0.016

0.873 ± 0.006

4.061 ± 0.014
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski