Amino acid dipepetide frequency for Sweet potato collusive virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.127AlaAla: 2.127 ± 1.038
0.0AlaCys: 0.0 ± 0.0
2.127AlaAsp: 2.127 ± 1.575
2.977AlaGlu: 2.977 ± 1.519
2.127AlaPhe: 2.127 ± 2.047
0.851AlaGly: 0.851 ± 0.546
0.0AlaHis: 0.0 ± 0.0
2.552AlaIle: 2.552 ± 0.882
5.955AlaLys: 5.955 ± 0.585
0.851AlaLeu: 0.851 ± 0.539
0.425AlaMet: 0.425 ± 0.417
2.552AlaAsn: 2.552 ± 1.82
0.851AlaPro: 0.851 ± 1.364
0.851AlaGln: 0.851 ± 0.546
1.701AlaArg: 1.701 ± 0.633
0.851AlaSer: 0.851 ± 0.694
2.552AlaThr: 2.552 ± 0.24
0.425AlaVal: 0.425 ± 0.27
0.425AlaTrp: 0.425 ± 0.682
2.977AlaTyr: 2.977 ± 1.423
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.425CysAsp: 0.425 ± 0.27
1.701CysGlu: 1.701 ± 1.092
0.0CysPhe: 0.0 ± 0.0
1.701CysGly: 1.701 ± 1.092
0.0CysHis: 0.0 ± 0.0
1.276CysIle: 1.276 ± 1.206
2.977CysLys: 2.977 ± 1.209
0.851CysLeu: 0.851 ± 0.694
0.0CysMet: 0.0 ± 0.0
0.425CysAsn: 0.425 ± 0.27
0.425CysPro: 0.425 ± 0.682
0.0CysGln: 0.0 ± 0.0
0.851CysArg: 0.851 ± 1.112
0.0CysSer: 0.0 ± 0.0
0.425CysThr: 0.425 ± 0.27
0.425CysVal: 0.425 ± 0.417
0.0CysTrp: 0.0 ± 0.0
0.425CysTyr: 0.425 ± 0.27
0.0CysXaa: 0.0 ± 0.0
Asp
2.977AspAla: 2.977 ± 0.649
1.276AspCys: 1.276 ± 0.441
2.977AspAsp: 2.977 ± 0.638
4.254AspGlu: 4.254 ± 0.979
1.701AspPhe: 1.701 ± 1.248
1.276AspGly: 1.276 ± 0.725
0.425AspHis: 0.425 ± 0.417
8.932AspIle: 8.932 ± 1.877
5.955AspLys: 5.955 ± 1.393
2.127AspLeu: 2.127 ± 0.924
1.276AspMet: 1.276 ± 1.25
4.254AspAsn: 4.254 ± 2.124
1.276AspPro: 1.276 ± 0.809
0.851AspGln: 0.851 ± 0.539
2.127AspArg: 2.127 ± 1.348
1.276AspSer: 1.276 ± 0.441
3.403AspThr: 3.403 ± 1.7
3.828AspVal: 3.828 ± 2.828
0.425AspTrp: 0.425 ± 0.27
5.104AspTyr: 5.104 ± 0.888
0.0AspXaa: 0.0 ± 0.0
Glu
2.977GluAla: 2.977 ± 1.133
0.425GluCys: 0.425 ± 0.417
4.679GluAsp: 4.679 ± 0.867
13.186GluGlu: 13.186 ± 1.072
4.679GluPhe: 4.679 ± 0.953
2.977GluGly: 2.977 ± 1.423
2.127GluHis: 2.127 ± 1.062
6.806GluIle: 6.806 ± 0.882
14.037GluLys: 14.037 ± 5.04
10.208GluLeu: 10.208 ± 1.335
2.977GluMet: 2.977 ± 0.713
7.231GluAsn: 7.231 ± 2.125
2.127GluPro: 2.127 ± 0.819
9.783GluGln: 9.783 ± 2.641
2.977GluArg: 2.977 ± 1.133
8.507GluSer: 8.507 ± 3.54
1.701GluThr: 1.701 ± 1.078
5.104GluVal: 5.104 ± 0.945
0.425GluTrp: 0.425 ± 0.417
2.552GluTyr: 2.552 ± 0.92
0.0GluXaa: 0.0 ± 0.0
Phe
0.425PheAla: 0.425 ± 0.682
0.0PheCys: 0.0 ± 0.0
2.127PheAsp: 2.127 ± 1.062
3.403PheGlu: 3.403 ± 1.533
0.0PhePhe: 0.0 ± 0.0
2.127PheGly: 2.127 ± 0.918
0.425PheHis: 0.425 ± 0.27
3.828PheIle: 3.828 ± 1.476
2.977PheLys: 2.977 ± 1.142
2.977PheLeu: 2.977 ± 0.638
0.851PheMet: 0.851 ± 0.354
0.851PheAsn: 0.851 ± 0.539
0.0PhePro: 0.0 ± 0.0
0.851PheGln: 0.851 ± 0.539
1.701PheArg: 1.701 ± 0.662
2.552PheSer: 2.552 ± 1.063
1.701PheThr: 1.701 ± 1.128
0.425PheVal: 0.425 ± 0.682
0.0PheTrp: 0.0 ± 0.0
2.552PheTyr: 2.552 ± 1.141
0.0PheXaa: 0.0 ± 0.0
Gly
1.276GlyAla: 1.276 ± 0.725
0.425GlyCys: 0.425 ± 0.27
2.552GlyAsp: 2.552 ± 0.452
2.977GlyGlu: 2.977 ± 0.292
1.701GlyPhe: 1.701 ± 1.128
0.425GlyGly: 0.425 ± 0.417
0.425GlyHis: 0.425 ± 0.27
6.806GlyIle: 6.806 ± 2.278
4.679GlyLys: 4.679 ± 0.626
2.552GlyLeu: 2.552 ± 1.309
0.851GlyMet: 0.851 ± 0.323
2.552GlyAsn: 2.552 ± 0.24
0.0GlyPro: 0.0 ± 0.0
1.276GlyGln: 1.276 ± 0.809
0.851GlyArg: 0.851 ± 0.539
1.701GlySer: 1.701 ± 1.309
1.701GlyThr: 1.701 ± 0.662
0.425GlyVal: 0.425 ± 0.417
0.0GlyTrp: 0.0 ± 0.0
2.977GlyTyr: 2.977 ± 1.142
0.0GlyXaa: 0.0 ± 0.0
His
0.851HisAla: 0.851 ± 0.546
0.0HisCys: 0.0 ± 0.0
0.425HisAsp: 0.425 ± 0.682
0.851HisGlu: 0.851 ± 0.354
0.0HisPhe: 0.0 ± 0.0
1.276HisGly: 1.276 ± 0.92
0.0HisHis: 0.0 ± 0.0
3.828HisIle: 3.828 ± 1.465
1.276HisLys: 1.276 ± 0.92
1.276HisLeu: 1.276 ± 0.472
0.0HisMet: 0.0 ± 0.0
0.851HisAsn: 0.851 ± 0.354
0.851HisPro: 0.851 ± 0.354
0.851HisGln: 0.851 ± 1.536
0.851HisArg: 0.851 ± 0.539
0.425HisSer: 0.425 ± 0.417
0.425HisThr: 0.425 ± 0.27
0.851HisVal: 0.851 ± 0.546
0.425HisTrp: 0.425 ± 0.417
0.851HisTyr: 0.851 ± 0.694
0.0HisXaa: 0.0 ± 0.0
Ile
2.977IleAla: 2.977 ± 1.871
1.276IleCys: 1.276 ± 0.472
8.082IleAsp: 8.082 ± 3.046
14.887IleGlu: 14.887 ± 1.649
3.828IlePhe: 3.828 ± 1.476
5.955IleGly: 5.955 ± 1.412
1.701IleHis: 1.701 ± 0.682
17.014IleIle: 17.014 ± 1.428
15.738IleLys: 15.738 ± 3.321
7.231IleLeu: 7.231 ± 2.309
1.701IleMet: 1.701 ± 0.662
8.507IleAsn: 8.507 ± 3.217
3.828IlePro: 3.828 ± 1.074
3.403IleGln: 3.403 ± 0.509
4.254IleArg: 4.254 ± 1.213
5.104IleSer: 5.104 ± 2.105
5.53IleThr: 5.53 ± 0.637
3.828IleVal: 3.828 ± 1.301
0.851IleTrp: 0.851 ± 1.536
7.231IleTyr: 7.231 ± 2.813
0.0IleXaa: 0.0 ± 0.0
Lys
3.403LysAla: 3.403 ± 1.57
0.425LysCys: 0.425 ± 0.682
7.231LysAsp: 7.231 ± 0.851
15.738LysGlu: 15.738 ± 2.734
4.679LysPhe: 4.679 ± 2.099
5.104LysGly: 5.104 ± 1.019
3.403LysHis: 3.403 ± 2.21
16.163LysIle: 16.163 ± 1.939
16.589LysLys: 16.589 ± 0.836
6.806LysLeu: 6.806 ± 1.752
3.828LysMet: 3.828 ± 1.033
11.91LysAsn: 11.91 ± 2.83
5.53LysPro: 5.53 ± 1.73
3.828LysGln: 3.828 ± 1.234
2.977LysArg: 2.977 ± 1.143
2.977LysSer: 2.977 ± 1.13
4.679LysThr: 4.679 ± 1.72
3.403LysVal: 3.403 ± 1.323
1.701LysTrp: 1.701 ± 0.682
6.38LysTyr: 6.38 ± 1.17
0.0LysXaa: 0.0 ± 0.0
Leu
2.127LeuAla: 2.127 ± 0.901
0.851LeuCys: 0.851 ± 0.546
4.679LeuAsp: 4.679 ± 2.965
8.932LeuGlu: 8.932 ± 0.615
2.127LeuPhe: 2.127 ± 0.236
3.403LeuGly: 3.403 ± 0.56
0.851LeuHis: 0.851 ± 0.546
4.679LeuIle: 4.679 ± 1.318
8.082LeuLys: 8.082 ± 1.452
5.104LeuLeu: 5.104 ± 2.352
0.851LeuMet: 0.851 ± 0.546
7.231LeuAsn: 7.231 ± 1.613
3.828LeuPro: 3.828 ± 0.943
1.276LeuGln: 1.276 ± 1.25
2.127LeuArg: 2.127 ± 0.819
3.828LeuSer: 3.828 ± 0.605
3.403LeuThr: 3.403 ± 2.944
3.403LeuVal: 3.403 ± 1.323
0.425LeuTrp: 0.425 ± 0.27
1.276LeuTyr: 1.276 ± 0.809
0.0LeuXaa: 0.0 ± 0.0
Met
0.425MetAla: 0.425 ± 1.103
0.0MetCys: 0.0 ± 0.0
1.276MetAsp: 1.276 ± 0.725
2.977MetGlu: 2.977 ± 0.696
0.425MetPhe: 0.425 ± 0.27
0.0MetGly: 0.0 ± 0.0
0.425MetHis: 0.425 ± 0.417
2.127MetIle: 2.127 ± 0.924
2.127MetLys: 2.127 ± 0.901
0.425MetLeu: 0.425 ± 0.27
0.851MetMet: 0.851 ± 0.546
2.127MetAsn: 2.127 ± 0.418
0.425MetPro: 0.425 ± 0.27
1.276MetGln: 1.276 ± 1.206
0.851MetArg: 0.851 ± 0.539
1.276MetSer: 1.276 ± 0.472
2.127MetThr: 2.127 ± 1.062
1.276MetVal: 1.276 ± 0.725
0.0MetTrp: 0.0 ± 0.0
1.276MetTyr: 1.276 ± 0.441
0.0MetXaa: 0.0 ± 0.0
Asn
2.127AsnAla: 2.127 ± 1.767
1.701AsnCys: 1.701 ± 0.682
3.403AsnAsp: 3.403 ± 2.157
5.104AsnGlu: 5.104 ± 0.396
0.851AsnPhe: 0.851 ± 0.354
2.127AsnGly: 2.127 ± 0.924
0.425AsnHis: 0.425 ± 1.103
10.208AsnIle: 10.208 ± 2.16
11.484AsnLys: 11.484 ± 3.675
6.806AsnLeu: 6.806 ± 2.623
2.127AsnMet: 2.127 ± 1.348
5.53AsnAsn: 5.53 ± 1.818
1.276AsnPro: 1.276 ± 1.25
2.977AsnGln: 2.977 ± 0.696
4.254AsnArg: 4.254 ± 1.085
5.104AsnSer: 5.104 ± 1.019
2.127AsnThr: 2.127 ± 0.236
2.552AsnVal: 2.552 ± 1.063
1.276AsnTrp: 1.276 ± 0.472
3.828AsnTyr: 3.828 ± 1.301
0.0AsnXaa: 0.0 ± 0.0
Pro
0.425ProAla: 0.425 ± 0.417
1.276ProCys: 1.276 ± 1.206
3.403ProAsp: 3.403 ± 0.735
2.977ProGlu: 2.977 ± 1.423
0.425ProPhe: 0.425 ± 0.417
0.425ProGly: 0.425 ± 0.27
0.851ProHis: 0.851 ± 0.354
5.53ProIle: 5.53 ± 1.528
2.977ProLys: 2.977 ± 1.133
2.127ProLeu: 2.127 ± 0.418
0.0ProMet: 0.0 ± 0.799
2.977ProAsn: 2.977 ± 1.13
1.701ProPro: 1.701 ± 0.709
0.851ProGln: 0.851 ± 0.354
0.851ProArg: 0.851 ± 0.354
1.276ProSer: 1.276 ± 0.92
0.851ProThr: 0.851 ± 0.354
0.425ProVal: 0.425 ± 0.417
1.276ProTrp: 1.276 ± 0.472
2.127ProTyr: 2.127 ± 0.79
0.0ProXaa: 0.0 ± 0.0
Gln
0.851GlnAla: 0.851 ± 0.354
0.425GlnCys: 0.425 ± 0.682
2.552GlnAsp: 2.552 ± 1.375
2.977GlnGlu: 2.977 ± 0.706
2.552GlnPhe: 2.552 ± 1.178
1.276GlnGly: 1.276 ± 1.25
1.276GlnHis: 1.276 ± 0.526
2.552GlnIle: 2.552 ± 0.24
2.977GlnLys: 2.977 ± 1.52
6.38GlnLeu: 6.38 ± 2.602
0.851GlnMet: 0.851 ± 0.546
3.828GlnAsn: 3.828 ± 0.76
0.851GlnPro: 0.851 ± 0.833
3.403GlnGln: 3.403 ± 0.735
0.425GlnArg: 0.425 ± 0.27
1.276GlnSer: 1.276 ± 0.472
0.851GlnThr: 0.851 ± 0.539
0.851GlnVal: 0.851 ± 0.539
0.0GlnTrp: 0.0 ± 0.0
2.552GlnTyr: 2.552 ± 1.042
0.0GlnXaa: 0.0 ± 0.0
Arg
2.127ArgAla: 2.127 ± 0.901
0.425ArgCys: 0.425 ± 0.27
0.425ArgAsp: 0.425 ± 0.27
2.977ArgGlu: 2.977 ± 1.283
0.425ArgPhe: 0.425 ± 0.682
0.851ArgGly: 0.851 ± 0.833
0.851ArgHis: 0.851 ± 1.364
6.38ArgIle: 6.38 ± 2.234
4.679ArgLys: 4.679 ± 1.013
1.276ArgLeu: 1.276 ± 1.206
1.701ArgMet: 1.701 ± 0.709
3.828ArgAsn: 3.828 ± 0.53
2.127ArgPro: 2.127 ± 0.236
1.276ArgGln: 1.276 ± 0.809
2.127ArgArg: 2.127 ± 0.819
1.276ArgSer: 1.276 ± 0.809
2.127ArgThr: 2.127 ± 0.924
0.851ArgVal: 0.851 ± 1.536
0.0ArgTrp: 0.0 ± 0.0
1.276ArgTyr: 1.276 ± 0.472
0.0ArgXaa: 0.0 ± 0.0
Ser
1.701SerAla: 1.701 ± 0.633
0.851SerCys: 0.851 ± 1.536
2.552SerAsp: 2.552 ± 0.452
7.656SerGlu: 7.656 ± 2.468
0.425SerPhe: 0.425 ± 0.27
0.851SerGly: 0.851 ± 0.833
0.0SerHis: 0.0 ± 0.0
7.656SerIle: 7.656 ± 2.347
6.806SerLys: 6.806 ± 2.1
2.127SerLeu: 2.127 ± 1.743
0.425SerMet: 0.425 ± 0.27
1.701SerAsn: 1.701 ± 1.078
1.701SerPro: 1.701 ± 1.128
1.701SerGln: 1.701 ± 0.682
3.828SerArg: 3.828 ± 1.323
2.552SerSer: 2.552 ± 0.452
1.276SerThr: 1.276 ± 0.526
0.851SerVal: 0.851 ± 0.539
0.425SerTrp: 0.425 ± 0.682
1.701SerTyr: 1.701 ± 1.089
0.0SerXaa: 0.0 ± 0.0
Thr
1.276ThrAla: 1.276 ± 1.311
0.851ThrCys: 0.851 ± 0.354
2.552ThrAsp: 2.552 ± 0.882
4.254ThrGlu: 4.254 ± 1.649
1.276ThrPhe: 1.276 ± 0.725
2.127ThrGly: 2.127 ± 1.062
0.851ThrHis: 0.851 ± 0.546
4.254ThrIle: 4.254 ± 0.808
4.254ThrLys: 4.254 ± 0.472
3.828ThrLeu: 3.828 ± 2.426
0.425ThrMet: 0.425 ± 0.27
2.977ThrAsn: 2.977 ± 1.142
1.701ThrPro: 1.701 ± 0.633
0.851ThrGln: 0.851 ± 0.354
0.425ThrArg: 0.425 ± 0.27
2.552ThrSer: 2.552 ± 1.042
0.425ThrThr: 0.425 ± 0.417
1.701ThrVal: 1.701 ± 0.662
0.0ThrTrp: 0.0 ± 0.0
4.679ThrTyr: 4.679 ± 1.274
0.0ThrXaa: 0.0 ± 0.0
Val
2.127ValAla: 2.127 ± 1.767
0.851ValCys: 0.851 ± 0.694
1.276ValAsp: 1.276 ± 1.311
2.552ValGlu: 2.552 ± 0.882
0.425ValPhe: 0.425 ± 1.103
0.851ValGly: 0.851 ± 0.539
0.851ValHis: 0.851 ± 1.364
4.254ValIle: 4.254 ± 1.58
6.38ValLys: 6.38 ± 0.695
2.977ValLeu: 2.977 ± 1.85
0.425ValMet: 0.425 ± 0.27
1.701ValAsn: 1.701 ± 0.662
0.425ValPro: 0.425 ± 0.417
0.425ValGln: 0.425 ± 0.27
2.127ValArg: 2.127 ± 0.236
0.0ValSer: 0.0 ± 0.0
1.701ValThr: 1.701 ± 1.092
1.276ValVal: 1.276 ± 1.206
1.276ValTrp: 1.276 ± 0.92
2.552ValTyr: 2.552 ± 1.141
0.0ValXaa: 0.0 ± 0.0
Trp
0.425TrpAla: 0.425 ± 0.27
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.276TrpGlu: 1.276 ± 1.25
0.425TrpPhe: 0.425 ± 0.27
0.425TrpGly: 0.425 ± 0.27
0.0TrpHis: 0.0 ± 0.0
1.701TrpIle: 1.701 ± 1.666
0.851TrpLys: 0.851 ± 0.546
0.0TrpLeu: 0.0 ± 0.0
0.425TrpMet: 0.425 ± 0.27
0.851TrpAsn: 0.851 ± 0.539
0.425TrpPro: 0.425 ± 0.27
0.851TrpGln: 0.851 ± 1.364
0.0TrpArg: 0.0 ± 0.0
0.425TrpSer: 0.425 ± 1.103
0.851TrpThr: 0.851 ± 0.354
0.425TrpVal: 0.425 ± 0.682
0.0TrpTrp: 0.0 ± 0.0
0.425TrpTyr: 0.425 ± 0.27
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.552TyrAla: 2.552 ± 0.803
0.851TyrCys: 0.851 ± 0.694
2.977TyrAsp: 2.977 ± 2.668
3.828TyrGlu: 3.828 ± 0.86
1.701TyrPhe: 1.701 ± 0.682
2.127TyrGly: 2.127 ± 1.339
1.276TyrHis: 1.276 ± 1.25
6.38TyrIle: 6.38 ± 0.922
5.955TyrLys: 5.955 ± 2.189
2.552TyrLeu: 2.552 ± 0.759
1.276TyrMet: 1.276 ± 0.725
3.403TyrAsn: 3.403 ± 0.509
3.828TyrPro: 3.828 ± 1.84
2.127TyrGln: 2.127 ± 1.339
1.701TyrArg: 1.701 ± 0.682
3.828TyrSer: 3.828 ± 0.379
3.403TyrThr: 3.403 ± 1.41
2.127TyrVal: 2.127 ± 0.236
0.851TyrTrp: 0.851 ± 0.354
2.977TyrTyr: 2.977 ± 1.408
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2352 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski