Amino acid dipepetide frequency for Kineobactrum salinum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.282AlaAla: 14.282 ± 0.162	1.257AlaCys: 1.257 ± 0.036	6.155AlaAsp: 6.155 ± 0.073	6.78AlaGlu: 6.78 ± 0.087	3.466AlaPhe: 3.466 ± 0.061	10.023AlaGly: 10.023 ± 0.109	2.02AlaHis: 2.02 ± 0.046	5.168AlaIle: 5.168 ± 0.068	2.348AlaLys: 2.348 ± 0.057	12.657AlaLeu: 12.657 ± 0.124	2.791AlaMet: 2.791 ± 0.056	2.769AlaAsn: 2.769 ± 0.052	4.543AlaPro: 4.543 ± 0.064	4.13AlaGln: 4.13 ± 0.06	7.997AlaArg: 7.997 ± 0.098	6.235AlaSer: 6.235 ± 0.073	5.646AlaThr: 5.646 ± 0.073	7.989AlaVal: 7.989 ± 0.091	1.454AlaTrp: 1.454 ± 0.033	2.386AlaTyr: 2.386 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.102CysAla: 1.102 ± 0.03	0.191CysCys: 0.191 ± 0.013	0.574CysAsp: 0.574 ± 0.026	0.631CysGlu: 0.631 ± 0.025	0.398CysPhe: 0.398 ± 0.019	1.055CysGly: 1.055 ± 0.033	0.379CysHis: 0.379 ± 0.026	0.492CysIle: 0.492 ± 0.022	0.252CysLys: 0.252 ± 0.015	1.072CysLeu: 1.072 ± 0.033	0.241CysMet: 0.241 ± 0.015	0.288CysAsn: 0.288 ± 0.013	0.525CysPro: 0.525 ± 0.022	0.354CysGln: 0.354 ± 0.018	0.788CysArg: 0.788 ± 0.025	0.674CysSer: 0.674 ± 0.023	0.463CysThr: 0.463 ± 0.018	0.69CysVal: 0.69 ± 0.027	0.16CysTrp: 0.16 ± 0.011	0.299CysTyr: 0.299 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	5.485AspAla: 5.485 ± 0.077	0.728AspCys: 0.728 ± 0.029	3.143AspAsp: 3.143 ± 0.06	3.585AspGlu: 3.585 ± 0.049	2.394AspPhe: 2.394 ± 0.049	4.726AspGly: 4.726 ± 0.07	1.268AspHis: 1.268 ± 0.03	3.319AspIle: 3.319 ± 0.057	1.576AspLys: 1.576 ± 0.042	5.511AspLeu: 5.511 ± 0.063	1.28AspMet: 1.28 ± 0.032	1.978AspAsn: 1.978 ± 0.045	3.266AspPro: 3.266 ± 0.061	2.137AspGln: 2.137 ± 0.045	3.775AspArg: 3.775 ± 0.059	3.583AspSer: 3.583 ± 0.065	2.96AspThr: 2.96 ± 0.05	3.707AspVal: 3.707 ± 0.064	0.983AspTrp: 0.983 ± 0.029	2.053AspTyr: 2.053 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	6.709GluAla: 6.709 ± 0.093	0.445GluCys: 0.445 ± 0.018	3.153GluAsp: 3.153 ± 0.051	3.643GluGlu: 3.643 ± 0.058	2.202GluPhe: 2.202 ± 0.047	4.1GluGly: 4.1 ± 0.066	1.553GluHis: 1.553 ± 0.037	3.173GluIle: 3.173 ± 0.053	1.848GluLys: 1.848 ± 0.048	7.669GluLeu: 7.669 ± 0.092	1.335GluMet: 1.335 ± 0.036	1.659GluAsn: 1.659 ± 0.04	2.809GluPro: 2.809 ± 0.078	3.792GluGln: 3.792 ± 0.058	4.682GluArg: 4.682 ± 0.067	3.083GluSer: 3.083 ± 0.056	3.085GluThr: 3.085 ± 0.055	4.451GluVal: 4.451 ± 0.063	0.749GluTrp: 0.749 ± 0.024	1.484GluTyr: 1.484 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.601PheAla: 3.601 ± 0.056	0.409PheCys: 0.409 ± 0.02	2.582PheAsp: 2.582 ± 0.053	2.129PheGlu: 2.129 ± 0.04	1.32PhePhe: 1.32 ± 0.037	3.267PheGly: 3.267 ± 0.059	0.819PheHis: 0.819 ± 0.026	1.718PheIle: 1.718 ± 0.032	0.932PheLys: 0.932 ± 0.029	3.281PheLeu: 3.281 ± 0.052	0.821PheMet: 0.821 ± 0.024	1.289PheAsn: 1.289 ± 0.036	1.48PhePro: 1.48 ± 0.035	1.198PheGln: 1.198 ± 0.032	2.202PheArg: 2.202 ± 0.044	2.601PheSer: 2.601 ± 0.053	1.96PheThr: 1.96 ± 0.043	2.407PheVal: 2.407 ± 0.044	0.454PheTrp: 0.454 ± 0.021	1.086PheTyr: 1.086 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	7.66GlyAla: 7.66 ± 0.09	0.93GlyCys: 0.93 ± 0.033	4.553GlyAsp: 4.553 ± 0.067	5.219GlyGlu: 5.219 ± 0.069	3.38GlyPhe: 3.38 ± 0.054	6.682GlyGly: 6.682 ± 0.091	1.799GlyHis: 1.799 ± 0.035	4.503GlyIle: 4.503 ± 0.068	2.822GlyLys: 2.822 ± 0.053	8.697GlyLeu: 8.697 ± 0.087	2.23GlyMet: 2.23 ± 0.046	2.417GlyAsn: 2.417 ± 0.047	3.064GlyPro: 3.064 ± 0.047	3.0GlyGln: 3.0 ± 0.054	5.415GlyArg: 5.415 ± 0.069	5.322GlySer: 5.322 ± 0.083	4.113GlyThr: 4.113 ± 0.066	5.803GlyVal: 5.803 ± 0.073	1.295GlyTrp: 1.295 ± 0.033	2.49GlyTyr: 2.49 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.014HisAla: 2.014 ± 0.043	0.405HisCys: 0.405 ± 0.02	1.137HisAsp: 1.137 ± 0.032	1.14HisGlu: 1.14 ± 0.036	0.935HisPhe: 0.935 ± 0.028	1.901HisGly: 1.901 ± 0.046	0.653HisHis: 0.653 ± 0.025	1.082HisIle: 1.082 ± 0.029	0.6HisLys: 0.6 ± 0.024	2.224HisLeu: 2.224 ± 0.049	0.495HisMet: 0.495 ± 0.022	0.719HisAsn: 0.719 ± 0.022	1.395HisPro: 1.395 ± 0.03	0.852HisGln: 0.852 ± 0.025	1.706HisArg: 1.706 ± 0.041	1.379HisSer: 1.379 ± 0.033	1.04HisThr: 1.04 ± 0.029	1.279HisVal: 1.279 ± 0.037	0.463HisTrp: 0.463 ± 0.02	0.827HisTyr: 0.827 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.789IleAla: 5.789 ± 0.075	0.533IleCys: 0.533 ± 0.021	3.363IleAsp: 3.363 ± 0.051	3.286IleGlu: 3.286 ± 0.058	1.454IlePhe: 1.454 ± 0.033	3.989IleGly: 3.989 ± 0.055	1.067IleHis: 1.067 ± 0.03	2.177IleIle: 2.177 ± 0.051	1.41IleLys: 1.41 ± 0.039	4.154IleLeu: 4.154 ± 0.061	0.903IleMet: 0.903 ± 0.03	1.822IleAsn: 1.822 ± 0.043	2.34IlePro: 2.34 ± 0.045	1.517IleGln: 1.517 ± 0.035	3.118IleArg: 3.118 ± 0.048	3.148IleSer: 3.148 ± 0.053	2.757IleThr: 2.757 ± 0.052	3.353IleVal: 3.353 ± 0.056	0.514IleTrp: 0.514 ± 0.022	1.329IleTyr: 1.329 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.763LysAla: 2.763 ± 0.059	0.19LysCys: 0.19 ± 0.014	1.297LysAsp: 1.297 ± 0.03	1.383LysGlu: 1.383 ± 0.037	0.762LysPhe: 0.762 ± 0.028	1.918LysGly: 1.918 ± 0.045	0.64LysHis: 0.64 ± 0.024	1.332LysIle: 1.332 ± 0.036	1.027LysLys: 1.027 ± 0.038	3.039LysLeu: 3.039 ± 0.059	0.623LysMet: 0.623 ± 0.023	0.797LysAsn: 0.797 ± 0.029	1.535LysPro: 1.535 ± 0.038	1.213LysGln: 1.213 ± 0.039	1.943LysArg: 1.943 ± 0.042	1.689LysSer: 1.689 ± 0.041	1.519LysThr: 1.519 ± 0.042	1.971LysVal: 1.971 ± 0.047	0.326LysTrp: 0.326 ± 0.018	0.684LysTyr: 0.684 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	13.584LeuAla: 13.584 ± 0.134	1.185LeuCys: 1.185 ± 0.037	6.369LeuAsp: 6.369 ± 0.078	7.05LeuGlu: 7.05 ± 0.089	3.766LeuPhe: 3.766 ± 0.061	8.397LeuGly: 8.397 ± 0.104	2.261LeuHis: 2.261 ± 0.046	4.42LeuIle: 4.42 ± 0.065	2.885LeuLys: 2.885 ± 0.067	12.654LeuLeu: 12.654 ± 0.161	2.234LeuMet: 2.234 ± 0.047	3.056LeuAsn: 3.056 ± 0.05	5.917LeuPro: 5.917 ± 0.077	5.349LeuGln: 5.349 ± 0.079	7.809LeuArg: 7.809 ± 0.094	6.363LeuSer: 6.363 ± 0.065	5.403LeuThr: 5.403 ± 0.078	7.718LeuVal: 7.718 ± 0.077	1.422LeuTrp: 1.422 ± 0.037	2.686LeuTyr: 2.686 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.699MetAla: 2.699 ± 0.047	0.156MetCys: 0.156 ± 0.01	1.212MetAsp: 1.212 ± 0.028	1.273MetGlu: 1.273 ± 0.031	0.636MetPhe: 0.636 ± 0.025	1.591MetGly: 1.591 ± 0.037	0.465MetHis: 0.465 ± 0.019	1.095MetIle: 1.095 ± 0.032	0.789MetLys: 0.789 ± 0.022	2.5MetLeu: 2.5 ± 0.048	0.536MetMet: 0.536 ± 0.023	0.803MetAsn: 0.803 ± 0.029	1.296MetPro: 1.296 ± 0.032	0.989MetGln: 0.989 ± 0.029	1.419MetArg: 1.419 ± 0.036	1.613MetSer: 1.613 ± 0.037	1.405MetThr: 1.405 ± 0.036	1.542MetVal: 1.542 ± 0.039	0.186MetTrp: 0.186 ± 0.012	0.412MetTyr: 0.412 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.965AsnAla: 2.965 ± 0.051	0.326AsnCys: 0.326 ± 0.02	1.54AsnAsp: 1.54 ± 0.042	1.532AsnGlu: 1.532 ± 0.035	1.1AsnPhe: 1.1 ± 0.033	2.361AsnGly: 2.361 ± 0.053	0.628AsnHis: 0.628 ± 0.022	1.657AsnIle: 1.657 ± 0.041	0.815AsnLys: 0.815 ± 0.027	3.041AsnLeu: 3.041 ± 0.056	0.628AsnMet: 0.628 ± 0.025	0.979AsnAsn: 0.979 ± 0.035	1.971AsnPro: 1.971 ± 0.043	1.054AsnGln: 1.054 ± 0.032	2.069AsnArg: 2.069 ± 0.038	1.756AsnSer: 1.756 ± 0.047	1.596AsnThr: 1.596 ± 0.045	1.873AsnVal: 1.873 ± 0.043	0.485AsnTrp: 0.485 ± 0.021	0.962AsnTyr: 0.962 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	5.974ProAla: 5.974 ± 0.077	0.386ProCys: 0.386 ± 0.019	3.389ProAsp: 3.389 ± 0.054	3.831ProGlu: 3.831 ± 0.083	1.631ProPhe: 1.631 ± 0.037	4.798ProGly: 4.798 ± 0.065	0.953ProHis: 0.953 ± 0.03	1.746ProIle: 1.746 ± 0.042	1.062ProLys: 1.062 ± 0.036	5.191ProLeu: 5.191 ± 0.073	1.078ProMet: 1.078 ± 0.028	1.165ProAsn: 1.165 ± 0.032	2.36ProPro: 2.36 ± 0.056	1.983ProGln: 1.983 ± 0.04	2.972ProArg: 2.972 ± 0.052	2.388ProSer: 2.388 ± 0.048	2.061ProThr: 2.061 ± 0.045	4.174ProVal: 4.174 ± 0.063	0.725ProTrp: 0.725 ± 0.023	1.127ProTyr: 1.127 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.888GlnAla: 4.888 ± 0.081	0.352GlnCys: 0.352 ± 0.019	1.926GlnAsp: 1.926 ± 0.041	2.171GlnGlu: 2.171 ± 0.047	1.399GlnPhe: 1.399 ± 0.033	2.965GlnGly: 2.965 ± 0.053	1.073GlnHis: 1.073 ± 0.033	1.793GlnIle: 1.793 ± 0.042	0.989GlnLys: 0.989 ± 0.03	5.572GlnLeu: 5.572 ± 0.082	0.903GlnMet: 0.903 ± 0.028	0.927GlnAsn: 0.927 ± 0.028	2.198GlnPro: 2.198 ± 0.047	2.772GlnGln: 2.772 ± 0.063	3.736GlnArg: 3.736 ± 0.069	2.159GlnSer: 2.159 ± 0.044	1.787GlnThr: 1.787 ± 0.04	2.956GlnVal: 2.956 ± 0.049	0.695GlnTrp: 0.695 ± 0.025	0.99GlnTyr: 0.99 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	6.682ArgAla: 6.682 ± 0.084	0.718ArgCys: 0.718 ± 0.026	4.206ArgAsp: 4.206 ± 0.057	5.193ArgGlu: 5.193 ± 0.073	2.726ArgPhe: 2.726 ± 0.048	4.761ArgGly: 4.761 ± 0.063	1.897ArgHis: 1.897 ± 0.042	3.577ArgIle: 3.577 ± 0.051	2.098ArgLys: 2.098 ± 0.052	7.904ArgLeu: 7.904 ± 0.08	1.645ArgMet: 1.645 ± 0.034	2.125ArgAsn: 2.125 ± 0.037	3.126ArgPro: 3.126 ± 0.049	3.602ArgGln: 3.602 ± 0.061	5.355ArgArg: 5.355 ± 0.076	3.945ArgSer: 3.945 ± 0.061	2.877ArgThr: 2.877 ± 0.049	4.696ArgVal: 4.696 ± 0.059	1.154ArgTrp: 1.154 ± 0.034	2.216ArgTyr: 2.216 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.319SerAla: 6.319 ± 0.078	0.707SerCys: 0.707 ± 0.027	3.351SerAsp: 3.351 ± 0.052	3.389SerGlu: 3.389 ± 0.054	2.186SerPhe: 2.186 ± 0.043	5.774SerGly: 5.774 ± 0.077	1.34SerHis: 1.34 ± 0.03	2.943SerIle: 2.943 ± 0.05	1.452SerLys: 1.452 ± 0.035	6.514SerLeu: 6.514 ± 0.079	1.398SerMet: 1.398 ± 0.031	1.715SerAsn: 1.715 ± 0.04	2.9SerPro: 2.9 ± 0.05	2.111SerGln: 2.111 ± 0.043	4.168SerArg: 4.168 ± 0.066	3.596SerSer: 3.596 ± 0.068	2.847SerThr: 2.847 ± 0.051	4.008SerVal: 4.008 ± 0.062	0.924SerTrp: 0.924 ± 0.03	1.782SerTyr: 1.782 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.864ThrAla: 5.864 ± 0.079	0.442ThrCys: 0.442 ± 0.018	2.861ThrAsp: 2.861 ± 0.055	2.77ThrGlu: 2.77 ± 0.052	1.624ThrPhe: 1.624 ± 0.037	4.905ThrGly: 4.905 ± 0.063	0.985ThrHis: 0.985 ± 0.03	2.354ThrIle: 2.354 ± 0.052	0.886ThrLys: 0.886 ± 0.03	6.227ThrLeu: 6.227 ± 0.069	1.018ThrMet: 1.018 ± 0.028	1.252ThrAsn: 1.252 ± 0.037	2.857ThrPro: 2.857 ± 0.056	1.573ThrGln: 1.573 ± 0.037	3.226ThrArg: 3.226 ± 0.054	2.726ThrSer: 2.726 ± 0.054	2.735ThrThr: 2.735 ± 0.07	4.339ThrVal: 4.339 ± 0.064	0.651ThrTrp: 0.651 ± 0.025	1.192ThrTyr: 1.192 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	8.133ValAla: 8.133 ± 0.094	0.741ValCys: 0.741 ± 0.025	4.402ValAsp: 4.402 ± 0.062	4.495ValGlu: 4.495 ± 0.066	2.567ValPhe: 2.567 ± 0.053	5.097ValGly: 5.097 ± 0.076	1.424ValHis: 1.424 ± 0.038	3.674ValIle: 3.674 ± 0.073	1.897ValLys: 1.897 ± 0.045	7.542ValLeu: 7.542 ± 0.083	1.607ValMet: 1.607 ± 0.038	2.278ValAsn: 2.278 ± 0.049	3.464ValPro: 3.464 ± 0.052	2.394ValGln: 2.394 ± 0.046	4.421ValArg: 4.421 ± 0.058	4.496ValSer: 4.496 ± 0.066	4.147ValThr: 4.147 ± 0.06	5.633ValVal: 5.633 ± 0.081	0.795ValTrp: 0.795 ± 0.024	1.829ValTyr: 1.829 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.122TrpAla: 1.122 ± 0.034	0.184TrpCys: 0.184 ± 0.014	0.677TrpAsp: 0.677 ± 0.025	0.683TrpGlu: 0.683 ± 0.026	0.523TrpPhe: 0.523 ± 0.022	0.89TrpGly: 0.89 ± 0.032	0.361TrpHis: 0.361 ± 0.02	0.616TrpIle: 0.616 ± 0.024	0.326TrpLys: 0.326 ± 0.015	1.989TrpLeu: 1.989 ± 0.045	0.327TrpMet: 0.327 ± 0.016	0.458TrpAsn: 0.458 ± 0.021	0.665TrpPro: 0.665 ± 0.026	0.927TrpGln: 0.927 ± 0.031	1.226TrpArg: 1.226 ± 0.033	0.923TrpSer: 0.923 ± 0.027	0.673TrpThr: 0.673 ± 0.023	0.878TrpVal: 0.878 ± 0.026	0.238TrpTrp: 0.238 ± 0.015	0.377TrpTyr: 0.377 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.459TyrAla: 2.459 ± 0.048	0.343TyrCys: 0.343 ± 0.015	1.568TyrAsp: 1.568 ± 0.042	1.438TyrGlu: 1.438 ± 0.037	1.087TyrPhe: 1.087 ± 0.028	2.196TyrGly: 2.196 ± 0.044	0.664TyrHis: 0.664 ± 0.023	1.184TyrIle: 1.184 ± 0.032	0.635TyrLys: 0.635 ± 0.027	3.092TyrLeu: 3.092 ± 0.05	0.522TyrMet: 0.522 ± 0.023	0.843TyrAsn: 0.843 ± 0.032	1.282TyrPro: 1.282 ± 0.035	1.304TyrGln: 1.304 ± 0.033	2.476TyrArg: 2.476 ± 0.039	1.744TyrSer: 1.744 ± 0.045	1.414TyrThr: 1.414 ± 0.043	1.569TyrVal: 1.569 ± 0.038	0.388TyrTrp: 0.388 ± 0.017	0.874TyrTyr: 0.874 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3712 proteins (1225903 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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