Amino acid dipepetide frequency for Canine mastadenovirus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.703AlaAla: 6.703 ± 0.761
1.282AlaCys: 1.282 ± 0.384
2.662AlaAsp: 2.662 ± 0.462
5.028AlaGlu: 5.028 ± 0.861
3.352AlaPhe: 3.352 ± 0.505
5.028AlaGly: 5.028 ± 0.702
2.169AlaHis: 2.169 ± 0.368
3.45AlaIle: 3.45 ± 0.438
3.056AlaLys: 3.056 ± 0.7
7.394AlaLeu: 7.394 ± 0.701
2.76AlaMet: 2.76 ± 0.57
3.352AlaAsn: 3.352 ± 0.974
4.83AlaPro: 4.83 ± 0.593
2.859AlaGln: 2.859 ± 0.413
4.338AlaArg: 4.338 ± 1.096
6.112AlaSer: 6.112 ± 0.702
4.732AlaThr: 4.732 ± 0.697
5.323AlaVal: 5.323 ± 0.564
0.789AlaTrp: 0.789 ± 0.263
2.563AlaTyr: 2.563 ± 0.498
0.0AlaXaa: 0.0 ± 0.0
Cys
2.169CysAla: 2.169 ± 0.589
0.986CysCys: 0.986 ± 0.378
0.493CysAsp: 0.493 ± 0.191
1.282CysGlu: 1.282 ± 0.415
0.986CysPhe: 0.986 ± 0.401
1.479CysGly: 1.479 ± 0.407
0.591CysHis: 0.591 ± 0.284
0.493CysIle: 0.493 ± 0.213
0.394CysLys: 0.394 ± 0.193
2.267CysLeu: 2.267 ± 0.491
1.084CysMet: 1.084 ± 0.387
0.986CysAsn: 0.986 ± 0.313
0.69CysPro: 0.69 ± 0.221
0.493CysGln: 0.493 ± 0.188
0.986CysArg: 0.986 ± 0.298
1.479CysSer: 1.479 ± 0.581
1.282CysThr: 1.282 ± 0.433
1.084CysVal: 1.084 ± 0.379
0.099CysTrp: 0.099 ± 0.09
1.084CysTyr: 1.084 ± 0.293
0.0CysXaa: 0.0 ± 0.0
Asp
2.465AspAla: 2.465 ± 0.687
0.986AspCys: 0.986 ± 0.33
2.465AspAsp: 2.465 ± 0.655
2.662AspGlu: 2.662 ± 0.627
1.972AspPhe: 1.972 ± 0.434
2.267AspGly: 2.267 ± 0.534
1.084AspHis: 1.084 ± 0.263
2.859AspIle: 2.859 ± 0.555
1.084AspLys: 1.084 ± 0.342
4.239AspLeu: 4.239 ± 0.547
1.282AspMet: 1.282 ± 0.353
2.07AspAsn: 2.07 ± 0.362
3.253AspPro: 3.253 ± 0.506
1.774AspGln: 1.774 ± 0.31
2.169AspArg: 2.169 ± 0.593
2.957AspSer: 2.957 ± 0.722
3.056AspThr: 3.056 ± 0.404
3.549AspVal: 3.549 ± 0.766
0.296AspTrp: 0.296 ± 0.14
1.479AspTyr: 1.479 ± 0.376
0.0AspXaa: 0.0 ± 0.0
Glu
5.521GluAla: 5.521 ± 0.897
0.986GluCys: 0.986 ± 0.294
3.746GluAsp: 3.746 ± 0.72
6.408GluGlu: 6.408 ± 1.117
1.873GluPhe: 1.873 ± 0.364
5.028GluGly: 5.028 ± 0.775
0.69GluHis: 0.69 ± 0.237
2.662GluIle: 2.662 ± 0.699
2.76GluLys: 2.76 ± 0.676
4.83GluLeu: 4.83 ± 0.806
1.577GluMet: 1.577 ± 0.422
4.042GluAsn: 4.042 ± 0.837
3.352GluPro: 3.352 ± 0.552
1.972GluGln: 1.972 ± 0.449
3.45GluArg: 3.45 ± 0.761
3.549GluSer: 3.549 ± 0.598
3.056GluThr: 3.056 ± 0.672
4.535GluVal: 4.535 ± 0.629
0.789GluTrp: 0.789 ± 0.22
0.986GluTyr: 0.986 ± 0.264
0.0GluXaa: 0.0 ± 0.0
Phe
2.169PheAla: 2.169 ± 0.304
1.183PheCys: 1.183 ± 0.403
2.366PheAsp: 2.366 ± 0.471
2.465PheGlu: 2.465 ± 0.445
2.267PhePhe: 2.267 ± 0.355
1.38PheGly: 1.38 ± 0.375
0.986PheHis: 0.986 ± 0.266
2.465PheIle: 2.465 ± 0.406
2.662PheLys: 2.662 ± 0.535
3.943PheLeu: 3.943 ± 0.63
1.676PheMet: 1.676 ± 0.358
1.972PheAsn: 1.972 ± 0.356
1.873PhePro: 1.873 ± 0.294
1.38PheGln: 1.38 ± 0.344
2.465PheArg: 2.465 ± 0.538
3.45PheSer: 3.45 ± 0.67
2.465PheThr: 2.465 ± 0.494
3.155PheVal: 3.155 ± 0.322
0.296PheTrp: 0.296 ± 0.201
2.07PheTyr: 2.07 ± 0.299
0.0PheXaa: 0.0 ± 0.0
Gly
6.211GlyAla: 6.211 ± 0.925
0.789GlyCys: 0.789 ± 0.267
2.267GlyAsp: 2.267 ± 0.386
2.662GlyGlu: 2.662 ± 0.588
2.76GlyPhe: 2.76 ± 0.568
4.239GlyGly: 4.239 ± 0.669
1.084GlyHis: 1.084 ± 0.351
2.267GlyIle: 2.267 ± 0.725
1.873GlyLys: 1.873 ± 0.633
5.816GlyLeu: 5.816 ± 1.355
1.282GlyMet: 1.282 ± 0.388
3.056GlyAsn: 3.056 ± 0.607
3.647GlyPro: 3.647 ± 0.703
2.859GlyGln: 2.859 ± 0.771
3.943GlyArg: 3.943 ± 0.729
4.633GlySer: 4.633 ± 0.54
3.253GlyThr: 3.253 ± 0.623
3.352GlyVal: 3.352 ± 0.684
0.69GlyTrp: 0.69 ± 0.286
1.183GlyTyr: 1.183 ± 0.403
0.0GlyXaa: 0.0 ± 0.0
His
1.577HisAla: 1.577 ± 0.469
0.493HisCys: 0.493 ± 0.365
0.69HisAsp: 0.69 ± 0.281
0.986HisGlu: 0.986 ± 0.35
0.887HisPhe: 0.887 ± 0.395
1.38HisGly: 1.38 ± 0.328
0.887HisHis: 0.887 ± 0.32
0.789HisIle: 0.789 ± 0.241
1.38HisLys: 1.38 ± 0.362
1.972HisLeu: 1.972 ± 0.441
0.493HisMet: 0.493 ± 0.247
1.479HisAsn: 1.479 ± 0.39
1.774HisPro: 1.774 ± 0.421
0.789HisGln: 0.789 ± 0.31
1.774HisArg: 1.774 ± 0.386
1.577HisSer: 1.577 ± 0.466
1.282HisThr: 1.282 ± 0.324
1.479HisVal: 1.479 ± 0.361
0.394HisTrp: 0.394 ± 0.179
1.183HisTyr: 1.183 ± 0.256
0.0HisXaa: 0.0 ± 0.0
Ile
2.859IleAla: 2.859 ± 0.662
0.887IleCys: 0.887 ± 0.367
1.774IleAsp: 1.774 ± 0.28
2.07IleGlu: 2.07 ± 0.483
2.169IlePhe: 2.169 ± 0.434
2.07IleGly: 2.07 ± 0.527
0.789IleHis: 0.789 ± 0.313
1.479IleIle: 1.479 ± 0.408
3.056IleLys: 3.056 ± 0.52
2.563IleLeu: 2.563 ± 0.424
1.183IleMet: 1.183 ± 0.3
2.76IleAsn: 2.76 ± 0.624
3.056IlePro: 3.056 ± 0.526
2.07IleGln: 2.07 ± 0.519
2.957IleArg: 2.957 ± 0.593
4.14IleSer: 4.14 ± 0.463
3.549IleThr: 3.549 ± 0.547
3.352IleVal: 3.352 ± 0.492
0.591IleTrp: 0.591 ± 0.195
0.69IleTyr: 0.69 ± 0.251
0.0IleXaa: 0.0 ± 0.0
Lys
3.253LysAla: 3.253 ± 0.777
1.084LysCys: 1.084 ± 0.456
2.169LysAsp: 2.169 ± 0.657
2.662LysGlu: 2.662 ± 0.573
2.169LysPhe: 2.169 ± 0.504
2.465LysGly: 2.465 ± 0.635
0.789LysHis: 0.789 ± 0.266
2.267LysIle: 2.267 ± 0.489
2.465LysLys: 2.465 ± 0.606
4.633LysLeu: 4.633 ± 0.805
0.789LysMet: 0.789 ± 0.274
2.267LysAsn: 2.267 ± 0.391
2.76LysPro: 2.76 ± 0.51
2.169LysGln: 2.169 ± 0.38
3.155LysArg: 3.155 ± 0.691
3.056LysSer: 3.056 ± 0.512
3.056LysThr: 3.056 ± 0.493
2.859LysVal: 2.859 ± 0.39
0.296LysTrp: 0.296 ± 0.176
1.577LysTyr: 1.577 ± 0.317
0.0LysXaa: 0.0 ± 0.0
Leu
7.788LeuAla: 7.788 ± 0.915
2.465LeuCys: 2.465 ± 0.623
3.943LeuAsp: 3.943 ± 0.521
5.323LeuGlu: 5.323 ± 0.8
2.859LeuPhe: 2.859 ± 0.456
5.521LeuGly: 5.521 ± 0.69
2.662LeuHis: 2.662 ± 0.478
3.746LeuIle: 3.746 ± 0.518
6.112LeuLys: 6.112 ± 0.981
8.675LeuLeu: 8.675 ± 1.013
1.774LeuMet: 1.774 ± 0.316
4.535LeuAsn: 4.535 ± 0.591
6.112LeuPro: 6.112 ± 0.69
4.436LeuGln: 4.436 ± 0.715
5.028LeuArg: 5.028 ± 0.731
6.408LeuSer: 6.408 ± 0.781
5.521LeuThr: 5.521 ± 1.23
5.619LeuVal: 5.619 ± 0.779
1.084LeuTrp: 1.084 ± 0.192
2.563LeuTyr: 2.563 ± 0.694
0.0LeuXaa: 0.0 ± 0.0
Met
3.056MetAla: 3.056 ± 0.652
0.591MetCys: 0.591 ± 0.212
1.282MetAsp: 1.282 ± 0.322
2.957MetGlu: 2.957 ± 0.55
0.986MetPhe: 0.986 ± 0.316
1.479MetGly: 1.479 ± 0.4
0.887MetHis: 0.887 ± 0.349
0.69MetIle: 0.69 ± 0.204
0.789MetLys: 0.789 ± 0.244
2.662MetLeu: 2.662 ± 0.462
0.591MetMet: 0.591 ± 0.217
0.986MetAsn: 0.986 ± 0.292
1.972MetPro: 1.972 ± 0.423
1.38MetGln: 1.38 ± 0.303
0.887MetArg: 0.887 ± 0.291
2.07MetSer: 2.07 ± 0.425
0.986MetThr: 0.986 ± 0.339
0.69MetVal: 0.69 ± 0.277
0.493MetTrp: 0.493 ± 0.217
0.986MetTyr: 0.986 ± 0.26
0.0MetXaa: 0.0 ± 0.0
Asn
3.253AsnAla: 3.253 ± 0.63
1.183AsnCys: 1.183 ± 0.531
2.366AsnAsp: 2.366 ± 0.373
2.76AsnGlu: 2.76 ± 0.551
2.859AsnPhe: 2.859 ± 0.475
2.859AsnGly: 2.859 ± 0.601
1.084AsnHis: 1.084 ± 0.285
3.056AsnIle: 3.056 ± 0.475
2.07AsnLys: 2.07 ± 0.35
4.535AsnLeu: 4.535 ± 0.824
1.38AsnMet: 1.38 ± 0.378
2.76AsnAsn: 2.76 ± 0.775
3.746AsnPro: 3.746 ± 0.681
1.38AsnGln: 1.38 ± 0.269
2.366AsnArg: 2.366 ± 0.384
3.056AsnSer: 3.056 ± 0.376
3.253AsnThr: 3.253 ± 0.462
3.352AsnVal: 3.352 ± 0.552
1.183AsnTrp: 1.183 ± 0.265
2.76AsnTyr: 2.76 ± 0.894
0.0AsnXaa: 0.0 ± 0.0
Pro
5.816ProAla: 5.816 ± 0.658
0.986ProCys: 0.986 ± 0.321
3.056ProAsp: 3.056 ± 0.488
4.732ProGlu: 4.732 ± 0.505
2.169ProPhe: 2.169 ± 0.553
2.662ProGly: 2.662 ± 0.835
1.38ProHis: 1.38 ± 0.342
2.267ProIle: 2.267 ± 0.374
2.957ProLys: 2.957 ± 0.459
5.816ProLeu: 5.816 ± 1.114
1.183ProMet: 1.183 ± 0.296
3.056ProAsn: 3.056 ± 0.465
6.901ProPro: 6.901 ± 1.678
1.774ProGln: 1.774 ± 0.424
4.929ProArg: 4.929 ± 0.657
5.126ProSer: 5.126 ± 0.663
4.436ProThr: 4.436 ± 0.607
3.647ProVal: 3.647 ± 0.48
0.197ProTrp: 0.197 ± 0.118
2.07ProTyr: 2.07 ± 0.583
0.0ProXaa: 0.0 ± 0.0
Gln
4.239GlnAla: 4.239 ± 0.639
0.69GlnCys: 0.69 ± 0.223
1.774GlnAsp: 1.774 ± 0.344
2.662GlnGlu: 2.662 ± 0.417
1.38GlnPhe: 1.38 ± 0.435
2.169GlnGly: 2.169 ± 0.356
1.183GlnHis: 1.183 ± 0.311
1.774GlnIle: 1.774 ± 0.431
2.07GlnLys: 2.07 ± 0.542
4.436GlnLeu: 4.436 ± 0.712
0.986GlnMet: 0.986 ± 0.315
2.366GlnAsn: 2.366 ± 0.378
1.972GlnPro: 1.972 ± 0.551
2.563GlnGln: 2.563 ± 0.46
2.662GlnArg: 2.662 ± 0.631
3.056GlnSer: 3.056 ± 0.611
2.662GlnThr: 2.662 ± 0.436
3.352GlnVal: 3.352 ± 0.684
0.394GlnTrp: 0.394 ± 0.175
0.789GlnTyr: 0.789 ± 0.229
0.0GlnXaa: 0.0 ± 0.0
Arg
5.028ArgAla: 5.028 ± 0.903
1.282ArgCys: 1.282 ± 0.396
2.563ArgAsp: 2.563 ± 0.458
2.859ArgGlu: 2.859 ± 0.556
1.972ArgPhe: 1.972 ± 0.329
4.436ArgGly: 4.436 ± 0.915
0.887ArgHis: 0.887 ± 0.319
1.972ArgIle: 1.972 ± 0.534
2.07ArgLys: 2.07 ± 0.463
5.028ArgLeu: 5.028 ± 0.738
1.183ArgMet: 1.183 ± 0.292
3.45ArgAsn: 3.45 ± 0.539
3.943ArgPro: 3.943 ± 0.745
3.155ArgGln: 3.155 ± 0.622
6.408ArgArg: 6.408 ± 1.605
3.647ArgSer: 3.647 ± 0.599
2.267ArgThr: 2.267 ± 0.469
4.338ArgVal: 4.338 ± 0.874
1.676ArgTrp: 1.676 ± 0.321
1.38ArgTyr: 1.38 ± 0.398
0.0ArgXaa: 0.0 ± 0.0
Ser
4.929SerAla: 4.929 ± 0.694
1.183SerCys: 1.183 ± 0.345
2.662SerAsp: 2.662 ± 0.556
3.549SerGlu: 3.549 ± 0.703
3.549SerPhe: 3.549 ± 0.695
4.83SerGly: 4.83 ± 0.721
1.972SerHis: 1.972 ± 0.462
4.436SerIle: 4.436 ± 0.639
4.338SerLys: 4.338 ± 0.86
6.802SerLeu: 6.802 ± 0.897
2.662SerMet: 2.662 ± 0.49
3.45SerAsn: 3.45 ± 0.606
4.436SerPro: 4.436 ± 0.853
3.352SerGln: 3.352 ± 0.687
3.943SerArg: 3.943 ± 0.777
4.929SerSer: 4.929 ± 0.809
3.155SerThr: 3.155 ± 0.629
3.746SerVal: 3.746 ± 0.629
1.38SerTrp: 1.38 ± 0.341
2.563SerTyr: 2.563 ± 0.787
0.0SerXaa: 0.0 ± 0.0
Thr
4.535ThrAla: 4.535 ± 0.733
1.774ThrCys: 1.774 ± 0.522
2.267ThrAsp: 2.267 ± 0.377
3.45ThrGlu: 3.45 ± 0.478
3.647ThrPhe: 3.647 ± 0.881
3.253ThrGly: 3.253 ± 0.7
1.282ThrHis: 1.282 ± 0.361
3.155ThrIle: 3.155 ± 0.415
1.972ThrLys: 1.972 ± 0.404
6.802ThrLeu: 6.802 ± 0.919
1.38ThrMet: 1.38 ± 0.391
2.859ThrAsn: 2.859 ± 0.542
4.535ThrPro: 4.535 ± 0.725
1.873ThrGln: 1.873 ± 0.512
2.465ThrArg: 2.465 ± 0.374
3.056ThrSer: 3.056 ± 0.798
3.845ThrThr: 3.845 ± 0.491
5.126ThrVal: 5.126 ± 0.742
0.986ThrTrp: 0.986 ± 0.309
2.563ThrTyr: 2.563 ± 0.617
0.0ThrXaa: 0.0 ± 0.0
Val
4.042ValAla: 4.042 ± 0.64
0.69ValCys: 0.69 ± 0.323
3.155ValAsp: 3.155 ± 0.721
4.042ValGlu: 4.042 ± 0.559
3.056ValPhe: 3.056 ± 0.827
2.859ValGly: 2.859 ± 0.659
1.183ValHis: 1.183 ± 0.369
2.169ValIle: 2.169 ± 0.323
2.465ValLys: 2.465 ± 0.594
5.718ValLeu: 5.718 ± 0.666
1.577ValMet: 1.577 ± 0.454
3.746ValAsn: 3.746 ± 0.707
3.746ValPro: 3.746 ± 0.483
3.845ValGln: 3.845 ± 0.465
4.14ValArg: 4.14 ± 0.765
5.126ValSer: 5.126 ± 1.083
5.816ValThr: 5.816 ± 0.743
5.323ValVal: 5.323 ± 0.875
0.394ValTrp: 0.394 ± 0.224
3.056ValTyr: 3.056 ± 0.518
0.0ValXaa: 0.0 ± 0.0
Trp
0.394TrpAla: 0.394 ± 0.185
0.099TrpCys: 0.099 ± 0.097
0.591TrpAsp: 0.591 ± 0.224
0.789TrpGlu: 0.789 ± 0.277
0.394TrpPhe: 0.394 ± 0.184
1.479TrpGly: 1.479 ± 0.458
0.197TrpHis: 0.197 ± 0.143
0.69TrpIle: 0.69 ± 0.226
0.69TrpLys: 0.69 ± 0.34
0.986TrpLeu: 0.986 ± 0.222
0.296TrpMet: 0.296 ± 0.193
0.591TrpAsn: 0.591 ± 0.205
0.789TrpPro: 0.789 ± 0.238
0.789TrpGln: 0.789 ± 0.312
0.394TrpArg: 0.394 ± 0.172
1.38TrpSer: 1.38 ± 0.398
0.789TrpThr: 0.789 ± 0.21
0.394TrpVal: 0.394 ± 0.212
0.099TrpTrp: 0.099 ± 0.09
0.591TrpTyr: 0.591 ± 0.307
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.774TyrAla: 1.774 ± 0.516
0.789TyrCys: 0.789 ± 0.309
1.774TyrAsp: 1.774 ± 0.404
2.465TyrGlu: 2.465 ± 0.442
1.38TyrPhe: 1.38 ± 0.437
0.986TyrGly: 0.986 ± 0.216
1.479TyrHis: 1.479 ± 0.392
1.38TyrIle: 1.38 ± 0.323
1.676TyrLys: 1.676 ± 0.383
3.056TyrLeu: 3.056 ± 0.624
1.183TyrMet: 1.183 ± 0.281
1.479TyrAsn: 1.479 ± 0.533
1.774TyrPro: 1.774 ± 0.38
2.267TyrGln: 2.267 ± 0.43
1.084TyrArg: 1.084 ± 0.313
3.056TyrSer: 3.056 ± 0.519
2.366TyrThr: 2.366 ± 0.478
1.873TyrVal: 1.873 ± 0.326
0.296TyrTrp: 0.296 ± 0.162
1.084TyrTyr: 1.084 ± 0.382
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 31 proteins (10145 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski