Amino acid dipepetide frequency for Tortoise microvirus 88

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.446AlaAla: 7.446 ± 1.088
0.745AlaCys: 0.745 ± 0.682
5.957AlaAsp: 5.957 ± 1.907
3.723AlaGlu: 3.723 ± 0.782
2.978AlaPhe: 2.978 ± 1.572
5.957AlaGly: 5.957 ± 1.515
1.489AlaHis: 1.489 ± 0.754
2.234AlaIle: 2.234 ± 1.748
3.723AlaLys: 3.723 ± 0.958
10.424AlaLeu: 10.424 ± 1.24
0.745AlaMet: 0.745 ± 0.61
5.957AlaAsn: 5.957 ± 2.656
10.424AlaPro: 10.424 ± 5.595
2.978AlaGln: 2.978 ± 1.491
10.424AlaArg: 10.424 ± 4.556
5.957AlaSer: 5.957 ± 2.757
2.978AlaThr: 2.978 ± 1.613
5.957AlaVal: 5.957 ± 2.141
0.745AlaTrp: 0.745 ± 0.583
1.489AlaTyr: 1.489 ± 1.195
0.0AlaXaa: 0.0 ± 0.0
Cys
0.745CysAla: 0.745 ± 1.057
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.489CysGlu: 1.489 ± 1.365
0.0CysPhe: 0.0 ± 0.0
1.489CysGly: 1.489 ± 1.365
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.745CysLys: 0.745 ± 0.682
1.489CysLeu: 1.489 ± 0.627
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.489CysPro: 1.489 ± 0.754
0.0CysGln: 0.0 ± 0.0
2.978CysArg: 2.978 ± 1.829
0.745CysSer: 0.745 ± 0.682
0.0CysThr: 0.0 ± 0.0
0.745CysVal: 0.745 ± 0.682
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.446AspAla: 7.446 ± 2.964
0.0AspCys: 0.0 ± 0.0
3.723AspAsp: 3.723 ± 1.318
2.978AspGlu: 2.978 ± 1.947
2.978AspPhe: 2.978 ± 1.613
2.978AspGly: 2.978 ± 1.324
0.0AspHis: 0.0 ± 0.0
1.489AspIle: 1.489 ± 0.658
2.234AspLys: 2.234 ± 0.465
3.723AspLeu: 3.723 ± 1.668
0.0AspMet: 0.0 ± 0.0
1.489AspAsn: 1.489 ± 1.165
4.468AspPro: 4.468 ± 1.905
2.234AspGln: 2.234 ± 1.045
2.234AspArg: 2.234 ± 1.193
0.745AspSer: 0.745 ± 0.682
1.489AspThr: 1.489 ± 1.221
2.234AspVal: 2.234 ± 1.045
1.489AspTrp: 1.489 ± 1.221
0.745AspTyr: 0.745 ± 0.61
0.0AspXaa: 0.0 ± 0.0
Glu
3.723GluAla: 3.723 ± 1.631
0.745GluCys: 0.745 ± 0.682
3.723GluAsp: 3.723 ± 1.322
1.489GluGlu: 1.489 ± 1.221
0.745GluPhe: 0.745 ± 0.61
5.212GluGly: 5.212 ± 1.729
0.745GluHis: 0.745 ± 0.583
3.723GluIle: 3.723 ± 1.03
0.0GluLys: 0.0 ± 0.0
4.468GluLeu: 4.468 ± 2.098
1.489GluMet: 1.489 ± 1.268
0.0GluAsn: 0.0 ± 0.0
1.489GluPro: 1.489 ± 0.658
5.957GluGln: 5.957 ± 2.588
3.723GluArg: 3.723 ± 1.094
2.234GluSer: 2.234 ± 0.465
3.723GluThr: 3.723 ± 1.63
5.212GluVal: 5.212 ± 3.252
1.489GluTrp: 1.489 ± 0.754
2.978GluTyr: 2.978 ± 0.78
0.0GluXaa: 0.0 ± 0.0
Phe
2.234PheAla: 2.234 ± 1.831
0.0PheCys: 0.0 ± 0.0
0.745PheAsp: 0.745 ± 0.682
2.978PheGlu: 2.978 ± 1.188
2.234PhePhe: 2.234 ± 1.092
4.468PheGly: 4.468 ± 1.45
0.745PheHis: 0.745 ± 0.682
3.723PheIle: 3.723 ± 1.253
2.978PheLys: 2.978 ± 1.508
1.489PheLeu: 1.489 ± 1.081
1.489PheMet: 1.489 ± 1.241
0.745PheAsn: 0.745 ± 0.61
0.745PhePro: 0.745 ± 0.682
1.489PheGln: 1.489 ± 1.221
4.468PheArg: 4.468 ± 1.687
5.212PheSer: 5.212 ± 1.973
2.234PheThr: 2.234 ± 1.07
2.234PheVal: 2.234 ± 1.092
0.0PheTrp: 0.0 ± 0.0
0.745PheTyr: 0.745 ± 0.61
0.0PheXaa: 0.0 ± 0.0
Gly
6.701GlyAla: 6.701 ± 2.158
0.0GlyCys: 0.0 ± 0.0
2.978GlyAsp: 2.978 ± 0.735
7.446GlyGlu: 7.446 ± 0.828
3.723GlyPhe: 3.723 ± 0.782
6.701GlyGly: 6.701 ± 1.682
0.745GlyHis: 0.745 ± 0.583
2.234GlyIle: 2.234 ± 1.092
0.745GlyLys: 0.745 ± 0.682
9.68GlyLeu: 9.68 ± 1.955
1.489GlyMet: 1.489 ± 0.754
2.978GlyAsn: 2.978 ± 1.955
2.978GlyPro: 2.978 ± 1.324
2.234GlyGln: 2.234 ± 0.975
2.978GlyArg: 2.978 ± 1.491
5.212GlySer: 5.212 ± 2.152
4.468GlyThr: 4.468 ± 1.292
6.701GlyVal: 6.701 ± 0.719
3.723GlyTrp: 3.723 ± 1.349
3.723GlyTyr: 3.723 ± 2.128
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.745HisCys: 0.745 ± 0.583
0.745HisAsp: 0.745 ± 0.682
0.745HisGlu: 0.745 ± 0.61
2.234HisPhe: 2.234 ± 1.315
2.234HisGly: 2.234 ± 0.997
0.0HisHis: 0.0 ± 0.0
0.745HisIle: 0.745 ± 0.583
2.234HisLys: 2.234 ± 1.193
2.234HisLeu: 2.234 ± 1.315
0.745HisMet: 0.745 ± 0.53
0.0HisAsn: 0.0 ± 0.0
1.489HisPro: 1.489 ± 0.627
0.745HisGln: 0.745 ± 0.682
2.978HisArg: 2.978 ± 1.254
0.745HisSer: 0.745 ± 1.057
0.745HisThr: 0.745 ± 0.61
1.489HisVal: 1.489 ± 0.754
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.723IleAla: 3.723 ± 1.253
0.0IleCys: 0.0 ± 0.0
1.489IleAsp: 1.489 ± 0.627
1.489IleGlu: 1.489 ± 0.658
0.745IlePhe: 0.745 ± 0.61
3.723IleGly: 3.723 ± 0.875
0.745IleHis: 0.745 ± 0.682
1.489IleIle: 1.489 ± 1.162
0.745IleLys: 0.745 ± 0.61
0.745IleLeu: 0.745 ± 1.057
1.489IleMet: 1.489 ± 1.162
1.489IleAsn: 1.489 ± 0.627
3.723IlePro: 3.723 ± 2.64
0.745IleGln: 0.745 ± 0.61
2.978IleArg: 2.978 ± 1.654
1.489IleSer: 1.489 ± 0.627
1.489IleThr: 1.489 ± 0.658
2.234IleVal: 2.234 ± 1.171
0.745IleTrp: 0.745 ± 0.583
1.489IleTyr: 1.489 ± 1.165
0.0IleXaa: 0.0 ± 0.0
Lys
3.723LysAla: 3.723 ± 2.819
0.745LysCys: 0.745 ± 0.682
2.978LysAsp: 2.978 ± 1.315
3.723LysGlu: 3.723 ± 0.958
4.468LysPhe: 4.468 ± 2.44
2.978LysGly: 2.978 ± 1.677
2.234LysHis: 2.234 ± 1.07
0.0LysIle: 0.0 ± 0.0
1.489LysLys: 1.489 ± 1.162
3.723LysLeu: 3.723 ± 1.565
0.745LysMet: 0.745 ± 0.61
1.489LysAsn: 1.489 ± 1.221
2.978LysPro: 2.978 ± 1.654
0.0LysGln: 0.0 ± 0.0
4.468LysArg: 4.468 ± 1.986
0.0LysSer: 0.0 ± 0.0
2.234LysThr: 2.234 ± 2.047
1.489LysVal: 1.489 ± 0.658
0.745LysTrp: 0.745 ± 0.682
0.745LysTyr: 0.745 ± 0.682
0.0LysXaa: 0.0 ± 0.0
Leu
10.424LeuAla: 10.424 ± 2.763
0.0LeuCys: 0.0 ± 0.0
2.234LeuAsp: 2.234 ± 1.831
3.723LeuGlu: 3.723 ± 1.79
0.745LeuPhe: 0.745 ± 0.61
6.701LeuGly: 6.701 ± 1.873
1.489LeuHis: 1.489 ± 0.658
2.978LeuIle: 2.978 ± 1.654
4.468LeuLys: 4.468 ± 2.2
5.212LeuLeu: 5.212 ± 1.729
1.489LeuMet: 1.489 ± 1.876
2.234LeuAsn: 2.234 ± 1.315
10.424LeuPro: 10.424 ± 2.991
3.723LeuGln: 3.723 ± 1.588
4.468LeuArg: 4.468 ± 2.204
6.701LeuSer: 6.701 ± 1.717
4.468LeuThr: 4.468 ± 1.254
4.468LeuVal: 4.468 ± 3.16
0.0LeuTrp: 0.0 ± 0.0
2.234LeuTyr: 2.234 ± 0.465
0.0LeuXaa: 0.0 ± 0.0
Met
1.489MetAla: 1.489 ± 1.351
0.745MetCys: 0.745 ± 0.61
0.745MetAsp: 0.745 ± 0.61
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.489MetGly: 1.489 ± 0.658
0.745MetHis: 0.745 ± 0.682
0.745MetIle: 0.745 ± 0.61
1.489MetLys: 1.489 ± 0.627
1.489MetLeu: 1.489 ± 0.658
1.489MetMet: 1.489 ± 1.221
0.745MetAsn: 0.745 ± 0.583
1.489MetPro: 1.489 ± 0.627
0.0MetGln: 0.0 ± 0.0
3.723MetArg: 3.723 ± 1.03
1.489MetSer: 1.489 ± 1.104
1.489MetThr: 1.489 ± 0.627
2.234MetVal: 2.234 ± 1.102
0.745MetTrp: 0.745 ± 0.61
0.745MetTyr: 0.745 ± 0.682
0.0MetXaa: 0.0 ± 0.0
Asn
2.978AsnAla: 2.978 ± 0.78
1.489AsnCys: 1.489 ± 1.365
1.489AsnAsp: 1.489 ± 1.165
1.489AsnGlu: 1.489 ± 1.162
2.234AsnPhe: 2.234 ± 0.465
2.234AsnGly: 2.234 ± 0.465
1.489AsnHis: 1.489 ± 1.104
0.745AsnIle: 0.745 ± 0.61
0.0AsnLys: 0.0 ± 0.0
3.723AsnLeu: 3.723 ± 0.867
1.489AsnMet: 1.489 ± 0.627
0.0AsnAsn: 0.0 ± 0.0
3.723AsnPro: 3.723 ± 2.225
1.489AsnGln: 1.489 ± 1.165
0.745AsnArg: 0.745 ± 1.057
3.723AsnSer: 3.723 ± 2.274
0.745AsnThr: 0.745 ± 0.61
0.745AsnVal: 0.745 ± 0.583
0.0AsnTrp: 0.0 ± 0.0
0.745AsnTyr: 0.745 ± 1.25
0.0AsnXaa: 0.0 ± 0.0
Pro
9.68ProAla: 9.68 ± 2.623
0.0ProCys: 0.0 ± 0.0
2.234ProAsp: 2.234 ± 1.102
5.212ProGlu: 5.212 ± 2.605
5.957ProPhe: 5.957 ± 0.699
4.468ProGly: 4.468 ± 1.255
0.745ProHis: 0.745 ± 0.682
0.745ProIle: 0.745 ± 1.057
3.723ProLys: 3.723 ± 0.867
5.957ProLeu: 5.957 ± 1.225
2.234ProMet: 2.234 ± 1.045
1.489ProAsn: 1.489 ± 2.113
5.957ProPro: 5.957 ± 3.275
2.234ProGln: 2.234 ± 1.092
9.68ProArg: 9.68 ± 5.128
5.212ProSer: 5.212 ± 0.853
3.723ProThr: 3.723 ± 0.875
5.957ProVal: 5.957 ± 2.656
2.234ProTrp: 2.234 ± 1.092
4.468ProTyr: 4.468 ± 2.787
0.0ProXaa: 0.0 ± 0.0
Gln
2.978GlnAla: 2.978 ± 1.264
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
0.745GlnGlu: 0.745 ± 0.61
3.723GlnPhe: 3.723 ± 0.782
2.978GlnGly: 2.978 ± 1.677
2.978GlnHis: 2.978 ± 0.78
1.489GlnIle: 1.489 ± 0.627
1.489GlnLys: 1.489 ± 1.365
2.234GlnLeu: 2.234 ± 1.193
1.489GlnMet: 1.489 ± 1.221
1.489GlnAsn: 1.489 ± 1.165
2.978GlnPro: 2.978 ± 1.254
0.745GlnGln: 0.745 ± 0.61
2.978GlnArg: 2.978 ± 1.436
4.468GlnSer: 4.468 ± 2.19
1.489GlnThr: 1.489 ± 0.627
4.468GlnVal: 4.468 ± 1.321
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
8.935ArgAla: 8.935 ± 4.717
2.234ArgCys: 2.234 ± 1.585
4.468ArgAsp: 4.468 ± 2.803
4.468ArgGlu: 4.468 ± 1.627
2.234ArgPhe: 2.234 ± 0.975
6.701ArgGly: 6.701 ± 3.131
2.234ArgHis: 2.234 ± 0.465
1.489ArgIle: 1.489 ± 1.195
5.212ArgLys: 5.212 ± 2.066
2.978ArgLeu: 2.978 ± 1.326
1.489ArgMet: 1.489 ± 0.754
1.489ArgAsn: 1.489 ± 1.327
7.446ArgPro: 7.446 ± 3.645
3.723ArgGln: 3.723 ± 1.87
6.701ArgArg: 6.701 ± 4.454
8.191ArgSer: 8.191 ± 3.278
3.723ArgThr: 3.723 ± 1.855
10.424ArgVal: 10.424 ± 2.557
0.745ArgTrp: 0.745 ± 0.682
2.978ArgTyr: 2.978 ± 1.829
0.0ArgXaa: 0.0 ± 0.0
Ser
5.212SerAla: 5.212 ± 1.632
0.745SerCys: 0.745 ± 0.583
4.468SerAsp: 4.468 ± 2.784
2.234SerGlu: 2.234 ± 1.193
0.745SerPhe: 0.745 ± 0.583
5.957SerGly: 5.957 ± 1.609
0.745SerHis: 0.745 ± 1.057
3.723SerIle: 3.723 ± 0.958
1.489SerLys: 1.489 ± 1.365
4.468SerLeu: 4.468 ± 2.098
0.745SerMet: 0.745 ± 0.61
2.978SerAsn: 2.978 ± 1.264
5.212SerPro: 5.212 ± 2.825
2.234SerGln: 2.234 ± 1.315
7.446SerArg: 7.446 ± 2.971
3.723SerSer: 3.723 ± 3.86
2.234SerThr: 2.234 ± 1.273
9.68SerVal: 9.68 ± 1.703
1.489SerTrp: 1.489 ± 1.221
1.489SerTyr: 1.489 ± 1.327
0.0SerXaa: 0.0 ± 0.0
Thr
6.701ThrAla: 6.701 ± 1.59
1.489ThrCys: 1.489 ± 1.365
2.234ThrAsp: 2.234 ± 1.07
2.978ThrGlu: 2.978 ± 0.78
0.745ThrPhe: 0.745 ± 0.61
2.234ThrGly: 2.234 ± 1.092
1.489ThrHis: 1.489 ± 1.165
0.745ThrIle: 0.745 ± 0.583
2.234ThrLys: 2.234 ± 0.997
2.978ThrLeu: 2.978 ± 1.955
1.489ThrMet: 1.489 ± 0.658
1.489ThrAsn: 1.489 ± 1.327
5.212ThrPro: 5.212 ± 1.007
2.234ThrGln: 2.234 ± 1.045
1.489ThrArg: 1.489 ± 1.195
2.234ThrSer: 2.234 ± 1.831
1.489ThrThr: 1.489 ± 0.627
4.468ThrVal: 4.468 ± 1.496
2.234ThrTrp: 2.234 ± 1.315
2.978ThrTyr: 2.978 ± 1.613
0.0ThrXaa: 0.0 ± 0.0
Val
6.701ValAla: 6.701 ± 1.633
2.234ValCys: 2.234 ± 1.193
3.723ValAsp: 3.723 ± 0.979
2.234ValGlu: 2.234 ± 1.102
1.489ValPhe: 1.489 ± 0.627
2.978ValGly: 2.978 ± 0.824
1.489ValHis: 1.489 ± 0.754
3.723ValIle: 3.723 ± 2.969
5.212ValLys: 5.212 ± 1.067
5.212ValLeu: 5.212 ± 2.306
1.489ValMet: 1.489 ± 1.033
4.468ValAsn: 4.468 ± 1.025
6.701ValPro: 6.701 ± 4.421
2.234ValGln: 2.234 ± 1.162
8.191ValArg: 8.191 ± 1.631
6.701ValSer: 6.701 ± 1.151
5.957ValThr: 5.957 ± 1.384
5.212ValVal: 5.212 ± 1.953
1.489ValTrp: 1.489 ± 1.165
0.745ValTyr: 0.745 ± 0.61
0.0ValXaa: 0.0 ± 0.0
Trp
0.745TrpAla: 0.745 ± 0.61
0.0TrpCys: 0.0 ± 0.0
0.745TrpAsp: 0.745 ± 0.682
0.745TrpGlu: 0.745 ± 0.583
0.745TrpPhe: 0.745 ± 0.682
2.234TrpGly: 2.234 ± 1.162
0.0TrpHis: 0.0 ± 0.0
0.745TrpIle: 0.745 ± 0.61
0.0TrpLys: 0.0 ± 0.0
2.234TrpLeu: 2.234 ± 1.045
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.745TrpPro: 0.745 ± 0.583
2.978TrpGln: 2.978 ± 1.654
2.234TrpArg: 2.234 ± 1.162
0.0TrpSer: 0.0 ± 0.0
4.468TrpThr: 4.468 ± 1.3
0.0TrpVal: 0.0 ± 0.0
1.489TrpTrp: 1.489 ± 0.627
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.745TyrAla: 0.745 ± 1.25
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.978TyrGlu: 2.978 ± 0.824
2.234TyrPhe: 2.234 ± 1.092
3.723TyrGly: 3.723 ± 0.867
0.745TyrHis: 0.745 ± 0.61
0.0TyrIle: 0.0 ± 0.0
0.745TyrLys: 0.745 ± 0.583
3.723TyrLeu: 3.723 ± 2.616
0.745TyrMet: 0.745 ± 0.682
0.745TyrAsn: 0.745 ± 0.583
2.234TyrPro: 2.234 ± 1.045
0.745TyrGln: 0.745 ± 0.583
2.978TyrArg: 2.978 ± 2.31
2.234TyrSer: 2.234 ± 0.465
0.0TyrThr: 0.0 ± 0.0
2.978TyrVal: 2.978 ± 0.78
0.745TyrTrp: 0.745 ± 0.61
1.489TyrTyr: 1.489 ± 1.221
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1344 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski