Amino acid dipepetide frequency for Ferrimonas balearica (strain DSM 9799 / CCM 4581 / KCTC 23876 / PAT)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.952AlaAla: 10.952 ± 0.147
1.162AlaCys: 1.162 ± 0.034
6.022AlaAsp: 6.022 ± 0.072
7.655AlaGlu: 7.655 ± 0.109
3.555AlaPhe: 3.555 ± 0.054
7.896AlaGly: 7.896 ± 0.083
2.079AlaHis: 2.079 ± 0.05
5.559AlaIle: 5.559 ± 0.065
3.792AlaLys: 3.792 ± 0.066
14.066AlaLeu: 14.066 ± 0.149
3.385AlaMet: 3.385 ± 0.058
3.425AlaAsn: 3.425 ± 0.064
4.548AlaPro: 4.548 ± 0.084
5.291AlaGln: 5.291 ± 0.088
6.192AlaArg: 6.192 ± 0.092
5.748AlaSer: 5.748 ± 0.077
4.964AlaThr: 4.964 ± 0.078
7.031AlaVal: 7.031 ± 0.089
1.298AlaTrp: 1.298 ± 0.031
2.496AlaTyr: 2.496 ± 0.043
0.0AlaXaa: 0.0 ± 0.0
Cys
0.969CysAla: 0.969 ± 0.031
0.151CysCys: 0.151 ± 0.013
0.659CysAsp: 0.659 ± 0.026
0.584CysGlu: 0.584 ± 0.021
0.336CysPhe: 0.336 ± 0.019
1.029CysGly: 1.029 ± 0.028
0.626CysHis: 0.626 ± 0.043
0.407CysIle: 0.407 ± 0.022
0.27CysLys: 0.27 ± 0.016
1.038CysLeu: 1.038 ± 0.026
0.198CysMet: 0.198 ± 0.014
0.311CysAsn: 0.311 ± 0.016
0.578CysPro: 0.578 ± 0.025
0.608CysGln: 0.608 ± 0.023
0.669CysArg: 0.669 ± 0.023
0.591CysSer: 0.591 ± 0.023
0.467CysThr: 0.467 ± 0.02
0.606CysVal: 0.606 ± 0.023
0.134CysTrp: 0.134 ± 0.01
0.283CysTyr: 0.283 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
6.116AspAla: 6.116 ± 0.076
0.601AspCys: 0.601 ± 0.026
3.271AspAsp: 3.271 ± 0.06
3.544AspGlu: 3.544 ± 0.052
2.069AspPhe: 2.069 ± 0.041
4.856AspGly: 4.856 ± 0.088
1.374AspHis: 1.374 ± 0.033
2.58AspIle: 2.58 ± 0.052
2.24AspLys: 2.24 ± 0.048
5.589AspLeu: 5.589 ± 0.072
1.242AspMet: 1.242 ± 0.033
2.199AspAsn: 2.199 ± 0.054
3.079AspPro: 3.079 ± 0.057
2.402AspGln: 2.402 ± 0.044
3.132AspArg: 3.132 ± 0.053
3.145AspSer: 3.145 ± 0.06
2.974AspThr: 2.974 ± 0.046
3.352AspVal: 3.352 ± 0.054
1.021AspTrp: 1.021 ± 0.032
1.924AspTyr: 1.924 ± 0.042
0.0AspXaa: 0.0 ± 0.0
Glu
6.903GluAla: 6.903 ± 0.089
0.475GluCys: 0.475 ± 0.018
2.579GluAsp: 2.579 ± 0.052
3.125GluGlu: 3.125 ± 0.073
1.945GluPhe: 1.945 ± 0.039
4.426GluGly: 4.426 ± 0.065
1.521GluHis: 1.521 ± 0.034
2.632GluIle: 2.632 ± 0.053
2.017GluLys: 2.017 ± 0.051
7.075GluLeu: 7.075 ± 0.087
1.646GluMet: 1.646 ± 0.035
1.623GluAsn: 1.623 ± 0.04
2.77GluPro: 2.77 ± 0.058
4.429GluGln: 4.429 ± 0.073
4.563GluArg: 4.563 ± 0.067
2.977GluSer: 2.977 ± 0.051
2.73GluThr: 2.73 ± 0.046
4.483GluVal: 4.483 ± 0.07
0.74GluTrp: 0.74 ± 0.023
1.437GluTyr: 1.437 ± 0.033
0.0GluXaa: 0.0 ± 0.0
Phe
3.71PheAla: 3.71 ± 0.061
0.415PheCys: 0.415 ± 0.019
2.657PheAsp: 2.657 ± 0.051
2.258PheGlu: 2.258 ± 0.044
1.347PhePhe: 1.347 ± 0.033
3.253PheGly: 3.253 ± 0.061
0.783PheHis: 0.783 ± 0.022
1.752PheIle: 1.752 ± 0.041
1.132PheLys: 1.132 ± 0.036
3.05PheLeu: 3.05 ± 0.052
0.867PheMet: 0.867 ± 0.027
1.418PheAsn: 1.418 ± 0.034
1.331PhePro: 1.331 ± 0.033
1.192PheGln: 1.192 ± 0.031
1.742PheArg: 1.742 ± 0.035
2.462PheSer: 2.462 ± 0.054
1.972PheThr: 1.972 ± 0.039
2.438PheVal: 2.438 ± 0.045
0.502PheTrp: 0.502 ± 0.023
1.117PheTyr: 1.117 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
7.056GlyAla: 7.056 ± 0.085
1.059GlyCys: 1.059 ± 0.032
4.408GlyAsp: 4.408 ± 0.077
5.051GlyGlu: 5.051 ± 0.072
3.233GlyPhe: 3.233 ± 0.055
5.897GlyGly: 5.897 ± 0.106
2.054GlyHis: 2.054 ± 0.039
4.128GlyIle: 4.128 ± 0.066
3.12GlyLys: 3.12 ± 0.064
8.657GlyLeu: 8.657 ± 0.096
2.2GlyMet: 2.2 ± 0.044
2.454GlyAsn: 2.454 ± 0.058
2.658GlyPro: 2.658 ± 0.046
4.192GlyGln: 4.192 ± 0.061
4.439GlyArg: 4.439 ± 0.063
4.246GlySer: 4.246 ± 0.063
3.865GlyThr: 3.865 ± 0.066
5.705GlyVal: 5.705 ± 0.076
1.26GlyTrp: 1.26 ± 0.031
2.578GlyTyr: 2.578 ± 0.046
0.0GlyXaa: 0.0 ± 0.0
His
1.994HisAla: 1.994 ± 0.04
0.398HisCys: 0.398 ± 0.018
1.182HisAsp: 1.182 ± 0.033
1.002HisGlu: 1.002 ± 0.029
1.108HisPhe: 1.108 ± 0.029
1.939HisGly: 1.939 ± 0.044
0.901HisHis: 0.901 ± 0.032
1.0HisIle: 1.0 ± 0.028
0.739HisLys: 0.739 ± 0.024
2.568HisLeu: 2.568 ± 0.05
0.467HisMet: 0.467 ± 0.021
0.835HisAsn: 0.835 ± 0.028
1.492HisPro: 1.492 ± 0.04
1.439HisGln: 1.439 ± 0.037
1.602HisArg: 1.602 ± 0.036
1.353HisSer: 1.353 ± 0.039
1.158HisThr: 1.158 ± 0.035
1.089HisVal: 1.089 ± 0.029
0.524HisTrp: 0.524 ± 0.022
0.988HisTyr: 0.988 ± 0.025
0.0HisXaa: 0.0 ± 0.0
Ile
5.278IleAla: 5.278 ± 0.075
0.479IleCys: 0.479 ± 0.018
3.196IleAsp: 3.196 ± 0.053
3.399IleGlu: 3.399 ± 0.055
1.313IlePhe: 1.313 ± 0.036
4.055IleGly: 4.055 ± 0.067
1.056IleHis: 1.056 ± 0.034
1.933IleIle: 1.933 ± 0.046
1.697IleLys: 1.697 ± 0.054
4.136IleLeu: 4.136 ± 0.059
0.887IleMet: 0.887 ± 0.03
1.858IleAsn: 1.858 ± 0.044
2.13IlePro: 2.13 ± 0.048
1.812IleGln: 1.812 ± 0.042
2.719IleArg: 2.719 ± 0.048
2.898IleSer: 2.898 ± 0.048
2.787IleThr: 2.787 ± 0.053
2.817IleVal: 2.817 ± 0.054
0.575IleTrp: 0.575 ± 0.02
1.214IleTyr: 1.214 ± 0.037
0.0IleXaa: 0.0 ± 0.0
Lys
4.233LysAla: 4.233 ± 0.077
0.207LysCys: 0.207 ± 0.013
1.652LysAsp: 1.652 ± 0.043
1.861LysGlu: 1.861 ± 0.046
0.903LysPhe: 0.903 ± 0.028
2.683LysGly: 2.683 ± 0.057
0.717LysHis: 0.717 ± 0.024
1.432LysIle: 1.432 ± 0.042
1.206LysLys: 1.206 ± 0.039
3.7LysLeu: 3.7 ± 0.064
0.852LysMet: 0.852 ± 0.029
0.866LysAsn: 0.866 ± 0.026
2.002LysPro: 2.002 ± 0.044
1.682LysGln: 1.682 ± 0.053
2.283LysArg: 2.283 ± 0.046
1.742LysSer: 1.742 ± 0.041
1.802LysThr: 1.802 ± 0.04
2.831LysVal: 2.831 ± 0.056
0.372LysTrp: 0.372 ± 0.018
0.747LysTyr: 0.747 ± 0.026
0.0LysXaa: 0.0 ± 0.0
Leu
14.465LeuAla: 14.465 ± 0.129
1.226LeuCys: 1.226 ± 0.03
6.516LeuAsp: 6.516 ± 0.078
6.302LeuGlu: 6.302 ± 0.085
3.94LeuPhe: 3.94 ± 0.066
8.491LeuGly: 8.491 ± 0.101
2.212LeuHis: 2.212 ± 0.044
4.759LeuIle: 4.759 ± 0.064
4.286LeuLys: 4.286 ± 0.066
12.547LeuLeu: 12.547 ± 0.145
3.221LeuMet: 3.221 ± 0.056
3.848LeuAsn: 3.848 ± 0.055
6.106LeuPro: 6.106 ± 0.068
3.962LeuGln: 3.962 ± 0.066
5.701LeuArg: 5.701 ± 0.074
7.738LeuSer: 7.738 ± 0.082
6.571LeuThr: 6.571 ± 0.08
8.334LeuVal: 8.334 ± 0.094
1.506LeuTrp: 1.506 ± 0.044
2.87LeuTyr: 2.87 ± 0.056
0.0LeuXaa: 0.0 ± 0.0
Met
3.495MetAla: 3.495 ± 0.062
0.184MetCys: 0.184 ± 0.012
1.31MetAsp: 1.31 ± 0.034
1.334MetGlu: 1.334 ± 0.035
0.683MetPhe: 0.683 ± 0.023
2.015MetGly: 2.015 ± 0.039
0.431MetHis: 0.431 ± 0.017
1.106MetIle: 1.106 ± 0.032
1.147MetLys: 1.147 ± 0.028
2.861MetLeu: 2.861 ± 0.052
0.809MetMet: 0.809 ± 0.029
0.888MetAsn: 0.888 ± 0.029
1.264MetPro: 1.264 ± 0.032
0.96MetGln: 0.96 ± 0.031
1.333MetArg: 1.333 ± 0.03
1.652MetSer: 1.652 ± 0.036
1.695MetThr: 1.695 ± 0.041
2.185MetVal: 2.185 ± 0.043
0.225MetTrp: 0.225 ± 0.013
0.383MetTyr: 0.383 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
3.299AsnAla: 3.299 ± 0.052
0.356AsnCys: 0.356 ± 0.017
1.867AsnAsp: 1.867 ± 0.047
1.704AsnGlu: 1.704 ± 0.038
1.056AsnPhe: 1.056 ± 0.034
2.777AsnGly: 2.777 ± 0.048
0.772AsnHis: 0.772 ± 0.025
1.473AsnIle: 1.473 ± 0.037
0.999AsnLys: 0.999 ± 0.028
3.499AsnLeu: 3.499 ± 0.063
0.676AsnMet: 0.676 ± 0.024
1.114AsnAsn: 1.114 ± 0.033
2.137AsnPro: 2.137 ± 0.045
1.625AsnGln: 1.625 ± 0.033
2.113AsnArg: 2.113 ± 0.042
1.597AsnSer: 1.597 ± 0.036
1.614AsnThr: 1.614 ± 0.038
1.912AsnVal: 1.912 ± 0.04
0.499AsnTrp: 0.499 ± 0.02
0.935AsnTyr: 0.935 ± 0.029
0.0AsnXaa: 0.0 ± 0.0
Pro
5.017ProAla: 5.017 ± 0.075
0.389ProCys: 0.389 ± 0.019
3.114ProAsp: 3.114 ± 0.058
3.827ProGlu: 3.827 ± 0.061
1.744ProPhe: 1.744 ± 0.042
3.752ProGly: 3.752 ± 0.052
1.105ProHis: 1.105 ± 0.033
2.028ProIle: 2.028 ± 0.04
1.624ProLys: 1.624 ± 0.041
5.437ProLeu: 5.437 ± 0.075
1.468ProMet: 1.468 ± 0.036
1.531ProAsn: 1.531 ± 0.037
1.647ProPro: 1.647 ± 0.044
2.171ProGln: 2.171 ± 0.051
2.172ProArg: 2.172 ± 0.047
2.452ProSer: 2.452 ± 0.04
2.26ProThr: 2.26 ± 0.049
3.97ProVal: 3.97 ± 0.061
0.773ProTrp: 0.773 ± 0.043
1.322ProTyr: 1.322 ± 0.035
0.0ProXaa: 0.0 ± 0.0
Gln
5.679GlnAla: 5.679 ± 0.098
0.489GlnCys: 0.489 ± 0.022
2.127GlnAsp: 2.127 ± 0.043
2.107GlnGlu: 2.107 ± 0.049
1.788GlnPhe: 1.788 ± 0.042
3.762GlnGly: 3.762 ± 0.06
1.304GlnHis: 1.304 ± 0.038
2.045GlnIle: 2.045 ± 0.038
1.254GlnLys: 1.254 ± 0.036
6.018GlnLeu: 6.018 ± 0.09
1.283GlnMet: 1.283 ± 0.033
1.151GlnAsn: 1.151 ± 0.029
2.589GlnPro: 2.589 ± 0.058
3.422GlnGln: 3.422 ± 0.096
3.613GlnArg: 3.613 ± 0.071
2.674GlnSer: 2.674 ± 0.048
2.155GlnThr: 2.155 ± 0.054
3.6GlnVal: 3.6 ± 0.062
1.015GlnTrp: 1.015 ± 0.029
1.344GlnTyr: 1.344 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
5.501ArgAla: 5.501 ± 0.063
0.617ArgCys: 0.617 ± 0.024
3.237ArgAsp: 3.237 ± 0.053
3.462ArgGlu: 3.462 ± 0.06
2.814ArgPhe: 2.814 ± 0.051
3.668ArgGly: 3.668 ± 0.056
1.786ArgHis: 1.786 ± 0.043
3.229ArgIle: 3.229 ± 0.054
1.808ArgLys: 1.808 ± 0.048
7.207ArgLeu: 7.207 ± 0.089
1.517ArgMet: 1.517 ± 0.033
1.708ArgAsn: 1.708 ± 0.041
2.612ArgPro: 2.612 ± 0.046
3.558ArgGln: 3.558 ± 0.065
3.918ArgArg: 3.918 ± 0.072
2.9ArgSer: 2.9 ± 0.047
2.58ArgThr: 2.58 ± 0.046
3.955ArgVal: 3.955 ± 0.062
1.038ArgTrp: 1.038 ± 0.027
2.227ArgTyr: 2.227 ± 0.04
0.0ArgXaa: 0.0 ± 0.0
Ser
5.903SerAla: 5.903 ± 0.072
0.611SerCys: 0.611 ± 0.028
3.513SerAsp: 3.513 ± 0.066
3.456SerGlu: 3.456 ± 0.053
1.986SerPhe: 1.986 ± 0.043
5.181SerGly: 5.181 ± 0.076
1.358SerHis: 1.358 ± 0.035
2.371SerIle: 2.371 ± 0.045
1.693SerLys: 1.693 ± 0.043
6.484SerLeu: 6.484 ± 0.077
1.274SerMet: 1.274 ± 0.034
1.722SerAsn: 1.722 ± 0.038
2.563SerPro: 2.563 ± 0.044
2.8SerGln: 2.8 ± 0.047
3.252SerArg: 3.252 ± 0.051
2.864SerSer: 2.864 ± 0.053
2.424SerThr: 2.424 ± 0.051
4.022SerVal: 4.022 ± 0.07
0.851SerTrp: 0.851 ± 0.028
1.583SerTyr: 1.583 ± 0.043
0.0SerXaa: 0.0 ± 0.0
Thr
4.913ThrAla: 4.913 ± 0.075
0.471ThrCys: 0.471 ± 0.025
2.813ThrAsp: 2.813 ± 0.05
3.06ThrGlu: 3.06 ± 0.06
1.688ThrPhe: 1.688 ± 0.04
4.335ThrGly: 4.335 ± 0.067
1.109ThrHis: 1.109 ± 0.029
2.42ThrIle: 2.42 ± 0.047
1.255ThrLys: 1.255 ± 0.035
7.41ThrLeu: 7.41 ± 0.075
1.022ThrMet: 1.022 ± 0.029
1.404ThrAsn: 1.404 ± 0.04
2.995ThrPro: 2.995 ± 0.048
2.016ThrGln: 2.016 ± 0.042
2.67ThrArg: 2.67 ± 0.041
2.469ThrSer: 2.469 ± 0.055
2.566ThrThr: 2.566 ± 0.052
3.978ThrVal: 3.978 ± 0.073
0.565ThrTrp: 0.565 ± 0.026
1.195ThrTyr: 1.195 ± 0.028
0.0ThrXaa: 0.0 ± 0.0
Val
8.049ValAla: 8.049 ± 0.103
0.709ValCys: 0.709 ± 0.024
4.184ValAsp: 4.184 ± 0.065
4.541ValGlu: 4.541 ± 0.058
2.292ValPhe: 2.292 ± 0.046
4.95ValGly: 4.95 ± 0.066
1.338ValHis: 1.338 ± 0.036
3.725ValIle: 3.725 ± 0.065
2.458ValLys: 2.458 ± 0.051
7.693ValLeu: 7.693 ± 0.09
2.066ValMet: 2.066 ± 0.047
2.41ValAsn: 2.41 ± 0.05
3.198ValPro: 3.198 ± 0.069
2.598ValGln: 2.598 ± 0.052
3.878ValArg: 3.878 ± 0.058
4.281ValSer: 4.281 ± 0.063
3.944ValThr: 3.944 ± 0.074
5.875ValVal: 5.875 ± 0.083
0.841ValTrp: 0.841 ± 0.026
1.642ValTyr: 1.642 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.208TrpAla: 1.208 ± 0.032
0.181TrpCys: 0.181 ± 0.013
0.762TrpAsp: 0.762 ± 0.026
0.577TrpGlu: 0.577 ± 0.023
0.56TrpPhe: 0.56 ± 0.021
0.986TrpGly: 0.986 ± 0.028
0.468TrpHis: 0.468 ± 0.018
0.58TrpIle: 0.58 ± 0.036
0.326TrpLys: 0.326 ± 0.016
2.08TrpLeu: 2.08 ± 0.048
0.382TrpMet: 0.382 ± 0.018
0.395TrpAsn: 0.395 ± 0.017
0.7TrpPro: 0.7 ± 0.024
1.319TrpGln: 1.319 ± 0.038
1.091TrpArg: 1.091 ± 0.034
0.694TrpSer: 0.694 ± 0.021
0.582TrpThr: 0.582 ± 0.022
0.914TrpVal: 0.914 ± 0.027
0.262TrpTrp: 0.262 ± 0.017
0.391TrpTyr: 0.391 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.377TyrAla: 2.377 ± 0.046
0.334TyrCys: 0.334 ± 0.015
1.642TyrAsp: 1.642 ± 0.04
1.245TyrGlu: 1.245 ± 0.032
1.041TyrPhe: 1.041 ± 0.031
2.308TyrGly: 2.308 ± 0.044
0.786TyrHis: 0.786 ± 0.024
1.08TyrIle: 1.08 ± 0.029
0.71TyrLys: 0.71 ± 0.023
3.484TyrLeu: 3.484 ± 0.053
0.497TyrMet: 0.497 ± 0.021
0.864TyrAsn: 0.864 ± 0.028
1.405TyrPro: 1.405 ± 0.033
1.94TyrGln: 1.94 ± 0.044
2.261TyrArg: 2.261 ± 0.043
1.427TyrSer: 1.427 ± 0.036
1.243TyrThr: 1.243 ± 0.033
1.578TyrVal: 1.578 ± 0.04
0.455TyrTrp: 0.455 ± 0.022
0.891TyrTyr: 0.891 ± 0.028
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3781 proteins (1264585 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski