Amino acid dipepetide frequency for Hubei sobemo-like virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.372AlaAla: 2.372 ± 0.279
1.186AlaCys: 1.186 ± 0.655
1.186AlaAsp: 1.186 ± 0.934
2.372AlaGlu: 2.372 ± 1.31
3.559AlaPhe: 3.559 ± 0.376
5.931AlaGly: 5.931 ± 0.097
0.0AlaHis: 0.0 ± 0.0
1.186AlaIle: 1.186 ± 0.655
4.745AlaLys: 4.745 ± 2.147
5.931AlaLeu: 5.931 ± 1.686
3.559AlaMet: 3.559 ± 1.213
1.186AlaAsn: 1.186 ± 0.934
3.559AlaPro: 3.559 ± 1.965
0.0AlaGln: 0.0 ± 0.0
2.372AlaArg: 2.372 ± 0.279
5.931AlaSer: 5.931 ± 1.492
0.0AlaThr: 0.0 ± 0.0
7.117AlaVal: 7.117 ± 2.426
0.0AlaTrp: 0.0 ± 0.0
4.745AlaTyr: 4.745 ± 1.031
0.0AlaXaa: 0.0 ± 0.0
Cys
1.186CysAla: 1.186 ± 0.934
0.0CysCys: 0.0 ± 0.0
1.186CysAsp: 1.186 ± 0.934
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.372CysGly: 2.372 ± 1.868
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.372CysLys: 2.372 ± 0.279
3.559CysLeu: 3.559 ± 2.802
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.186CysGln: 1.186 ± 0.934
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
2.372CysVal: 2.372 ± 1.868
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
2.372AspAsp: 2.372 ± 0.279
3.559AspGlu: 3.559 ± 1.965
2.372AspPhe: 2.372 ± 1.31
3.559AspGly: 3.559 ± 0.376
0.0AspHis: 0.0 ± 0.0
2.372AspIle: 2.372 ± 1.868
1.186AspLys: 1.186 ± 0.934
4.745AspLeu: 4.745 ± 1.031
1.186AspMet: 1.186 ± 0.655
0.0AspAsn: 0.0 ± 0.0
2.372AspPro: 2.372 ± 0.279
0.0AspGln: 0.0 ± 0.0
2.372AspArg: 2.372 ± 1.868
3.559AspSer: 3.559 ± 1.213
4.745AspThr: 4.745 ± 2.147
2.372AspVal: 2.372 ± 1.31
1.186AspTrp: 1.186 ± 0.934
2.372AspTyr: 2.372 ± 1.31
0.0AspXaa: 0.0 ± 0.0
Glu
8.304GluAla: 8.304 ± 0.182
0.0GluCys: 0.0 ± 0.0
4.745GluAsp: 4.745 ± 0.558
3.559GluGlu: 3.559 ± 1.965
2.372GluPhe: 2.372 ± 0.279
9.49GluGly: 9.49 ± 2.062
1.186GluHis: 1.186 ± 0.934
3.559GluIle: 3.559 ± 1.965
2.372GluLys: 2.372 ± 0.279
4.745GluLeu: 4.745 ± 0.558
1.186GluMet: 1.186 ± 0.934
1.186GluAsn: 1.186 ± 0.655
5.931GluPro: 5.931 ± 0.097
1.186GluGln: 1.186 ± 0.655
1.186GluArg: 1.186 ± 0.934
3.559GluSer: 3.559 ± 1.965
3.559GluThr: 3.559 ± 0.376
5.931GluVal: 5.931 ± 1.686
0.0GluTrp: 0.0 ± 0.0
2.372GluTyr: 2.372 ± 0.279
0.0GluXaa: 0.0 ± 0.0
Phe
3.559PheAla: 3.559 ± 1.213
1.186PheCys: 1.186 ± 0.934
0.0PheAsp: 0.0 ± 0.0
2.372PheGlu: 2.372 ± 1.868
1.186PhePhe: 1.186 ± 0.655
4.745PheGly: 4.745 ± 1.031
0.0PheHis: 0.0 ± 0.0
1.186PheIle: 1.186 ± 0.655
5.931PheLys: 5.931 ± 4.671
4.745PheLeu: 4.745 ± 1.031
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
2.372PheGln: 2.372 ± 0.279
1.186PheArg: 1.186 ± 0.934
4.745PheSer: 4.745 ± 2.621
1.186PheThr: 1.186 ± 0.655
3.559PheVal: 3.559 ± 0.376
1.186PheTrp: 1.186 ± 0.934
1.186PheTyr: 1.186 ± 0.655
0.0PheXaa: 0.0 ± 0.0
Gly
5.931GlyAla: 5.931 ± 1.686
1.186GlyCys: 1.186 ± 0.934
2.372GlyAsp: 2.372 ± 0.279
0.0GlyGlu: 0.0 ± 0.0
7.117GlyPhe: 7.117 ± 2.342
2.372GlyGly: 2.372 ± 0.279
1.186GlyHis: 1.186 ± 0.934
3.559GlyIle: 3.559 ± 1.213
4.745GlyLys: 4.745 ± 2.621
5.931GlyLeu: 5.931 ± 3.276
2.372GlyMet: 2.372 ± 0.474
2.372GlyAsn: 2.372 ± 0.279
1.186GlyPro: 1.186 ± 0.655
4.745GlyGln: 4.745 ± 1.031
7.117GlyArg: 7.117 ± 2.426
7.117GlySer: 7.117 ± 2.342
2.372GlyThr: 2.372 ± 1.868
4.745GlyVal: 4.745 ± 1.031
3.559GlyTrp: 3.559 ± 2.802
2.372GlyTyr: 2.372 ± 0.279
0.0GlyXaa: 0.0 ± 0.0
His
1.186HisAla: 1.186 ± 0.655
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.186HisLys: 1.186 ± 0.655
3.559HisLeu: 3.559 ± 0.376
3.559HisMet: 3.559 ± 1.965
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
1.186HisGln: 1.186 ± 0.934
1.186HisArg: 1.186 ± 0.934
0.0HisSer: 0.0 ± 0.0
1.186HisThr: 1.186 ± 0.934
3.559HisVal: 3.559 ± 0.376
0.0HisTrp: 0.0 ± 0.0
1.186HisTyr: 1.186 ± 0.934
0.0HisXaa: 0.0 ± 0.0
Ile
3.559IleAla: 3.559 ± 1.213
2.372IleCys: 2.372 ± 1.868
2.372IleAsp: 2.372 ± 0.279
2.372IleGlu: 2.372 ± 1.31
2.372IlePhe: 2.372 ± 1.868
1.186IleGly: 1.186 ± 0.934
0.0IleHis: 0.0 ± 0.0
1.186IleIle: 1.186 ± 0.655
1.186IleLys: 1.186 ± 0.655
4.745IleLeu: 4.745 ± 1.031
5.931IleMet: 5.931 ± 0.097
1.186IleAsn: 1.186 ± 0.934
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
3.559IleArg: 3.559 ± 1.213
2.372IleSer: 2.372 ± 0.279
2.372IleThr: 2.372 ± 0.279
1.186IleVal: 1.186 ± 0.655
0.0IleTrp: 0.0 ± 0.0
3.559IleTyr: 3.559 ± 1.213
0.0IleXaa: 0.0 ± 0.0
Lys
3.559LysAla: 3.559 ± 0.376
0.0LysCys: 0.0 ± 0.0
2.372LysAsp: 2.372 ± 1.868
2.372LysGlu: 2.372 ± 0.279
0.0LysPhe: 0.0 ± 0.0
8.304LysGly: 8.304 ± 2.997
1.186LysHis: 1.186 ± 0.934
1.186LysIle: 1.186 ± 0.934
1.186LysLys: 1.186 ± 0.655
14.235LysLeu: 14.235 ± 1.674
2.372LysMet: 2.372 ± 1.31
2.372LysAsn: 2.372 ± 1.31
1.186LysPro: 1.186 ± 0.934
3.559LysGln: 3.559 ± 1.965
4.745LysArg: 4.745 ± 1.031
7.117LysSer: 7.117 ± 2.426
0.0LysThr: 0.0 ± 0.0
3.559LysVal: 3.559 ± 1.965
0.0LysTrp: 0.0 ± 0.0
3.559LysTyr: 3.559 ± 0.376
0.0LysXaa: 0.0 ± 0.0
Leu
9.49LeuAla: 9.49 ± 1.116
2.372LeuCys: 2.372 ± 1.868
3.559LeuAsp: 3.559 ± 1.213
11.862LeuGlu: 11.862 ± 3.373
5.931LeuPhe: 5.931 ± 1.492
5.931LeuGly: 5.931 ± 0.097
2.372LeuHis: 2.372 ± 0.279
5.931LeuIle: 5.931 ± 3.081
2.372LeuLys: 2.372 ± 1.31
4.745LeuLeu: 4.745 ± 0.558
4.745LeuMet: 4.745 ± 2.621
2.372LeuAsn: 2.372 ± 0.279
2.372LeuPro: 2.372 ± 1.31
3.559LeuGln: 3.559 ± 1.213
5.931LeuArg: 5.931 ± 0.097
5.931LeuSer: 5.931 ± 0.097
4.745LeuThr: 4.745 ± 2.147
8.304LeuVal: 8.304 ± 1.407
0.0LeuTrp: 0.0 ± 0.0
4.745LeuTyr: 4.745 ± 1.031
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
4.745MetAsp: 4.745 ± 1.031
3.559MetGlu: 3.559 ± 0.376
0.0MetPhe: 0.0 ± 0.0
2.372MetGly: 2.372 ± 1.31
2.372MetHis: 2.372 ± 1.31
2.372MetIle: 2.372 ± 1.868
2.372MetLys: 2.372 ± 0.279
4.745MetLeu: 4.745 ± 1.031
1.186MetMet: 1.186 ± 0.655
2.372MetAsn: 2.372 ± 0.279
0.0MetPro: 0.0 ± 0.0
3.559MetGln: 3.559 ± 0.376
1.186MetArg: 1.186 ± 0.655
1.186MetSer: 1.186 ± 0.655
1.186MetThr: 1.186 ± 0.655
4.745MetVal: 4.745 ± 0.558
2.372MetTrp: 2.372 ± 1.31
1.186MetTyr: 1.186 ± 0.934
0.0MetXaa: 0.0 ± 0.0
Asn
1.186AsnAla: 1.186 ± 0.655
1.186AsnCys: 1.186 ± 0.934
0.0AsnAsp: 0.0 ± 0.0
3.559AsnGlu: 3.559 ± 0.376
1.186AsnPhe: 1.186 ± 0.655
1.186AsnGly: 1.186 ± 0.934
1.186AsnHis: 1.186 ± 0.655
1.186AsnIle: 1.186 ± 0.655
2.372AsnLys: 2.372 ± 0.279
4.745AsnLeu: 4.745 ± 2.621
0.0AsnMet: 0.0 ± 0.0
1.186AsnAsn: 1.186 ± 0.655
2.372AsnPro: 2.372 ± 1.868
1.186AsnGln: 1.186 ± 0.934
1.186AsnArg: 1.186 ± 0.655
4.745AsnSer: 4.745 ± 1.031
0.0AsnThr: 0.0 ± 0.0
2.372AsnVal: 2.372 ± 0.279
2.372AsnTrp: 2.372 ± 1.868
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.559ProAla: 3.559 ± 0.376
1.186ProCys: 1.186 ± 0.934
5.931ProAsp: 5.931 ± 3.276
3.559ProGlu: 3.559 ± 2.802
0.0ProPhe: 0.0 ± 0.0
2.372ProGly: 2.372 ± 0.279
2.372ProHis: 2.372 ± 0.279
2.372ProIle: 2.372 ± 0.279
2.372ProLys: 2.372 ± 1.31
2.372ProLeu: 2.372 ± 0.279
1.186ProMet: 1.186 ± 0.934
0.0ProAsn: 0.0 ± 0.0
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
1.186ProArg: 1.186 ± 0.655
0.0ProSer: 0.0 ± 0.0
0.0ProThr: 0.0 ± 0.0
5.931ProVal: 5.931 ± 1.492
0.0ProTrp: 0.0 ± 0.0
3.559ProTyr: 3.559 ± 1.965
0.0ProXaa: 0.0 ± 0.0
Gln
1.186GlnAla: 1.186 ± 0.655
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.745GlnGlu: 4.745 ± 0.558
2.372GlnPhe: 2.372 ± 1.868
1.186GlnGly: 1.186 ± 0.655
1.186GlnHis: 1.186 ± 0.934
1.186GlnIle: 1.186 ± 0.655
2.372GlnLys: 2.372 ± 0.279
1.186GlnLeu: 1.186 ± 0.655
1.186GlnMet: 1.186 ± 0.934
1.186GlnAsn: 1.186 ± 0.655
3.559GlnPro: 3.559 ± 1.213
5.931GlnGln: 5.931 ± 1.686
4.745GlnArg: 4.745 ± 1.031
3.559GlnSer: 3.559 ± 0.376
2.372GlnThr: 2.372 ± 0.279
7.117GlnVal: 7.117 ± 2.342
0.0GlnTrp: 0.0 ± 0.0
1.186GlnTyr: 1.186 ± 0.934
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
1.186ArgCys: 1.186 ± 0.934
0.0ArgAsp: 0.0 ± 0.0
3.559ArgGlu: 3.559 ± 0.376
3.559ArgPhe: 3.559 ± 2.802
1.186ArgGly: 1.186 ± 0.655
0.0ArgHis: 0.0 ± 0.0
3.559ArgIle: 3.559 ± 0.376
7.117ArgLys: 7.117 ± 2.342
5.931ArgLeu: 5.931 ± 4.671
2.372ArgMet: 2.372 ± 1.31
7.117ArgAsn: 7.117 ± 2.426
2.372ArgPro: 2.372 ± 1.31
1.186ArgGln: 1.186 ± 0.655
2.372ArgArg: 2.372 ± 1.31
1.186ArgSer: 1.186 ± 0.655
2.372ArgThr: 2.372 ± 0.279
8.304ArgVal: 8.304 ± 1.407
0.0ArgTrp: 0.0 ± 0.0
2.372ArgTyr: 2.372 ± 0.279
0.0ArgXaa: 0.0 ± 0.0
Ser
3.559SerAla: 3.559 ± 1.213
0.0SerCys: 0.0 ± 0.0
1.186SerAsp: 1.186 ± 0.655
4.745SerGlu: 4.745 ± 1.031
4.745SerPhe: 4.745 ± 0.558
5.931SerGly: 5.931 ± 1.686
0.0SerHis: 0.0 ± 0.0
1.186SerIle: 1.186 ± 0.655
3.559SerLys: 3.559 ± 1.965
5.931SerLeu: 5.931 ± 1.492
2.372SerMet: 2.372 ± 0.279
3.559SerAsn: 3.559 ± 1.965
2.372SerPro: 2.372 ± 0.279
1.186SerGln: 1.186 ± 0.655
3.559SerArg: 3.559 ± 0.376
4.745SerSer: 4.745 ± 1.031
5.931SerThr: 5.931 ± 0.097
4.745SerVal: 4.745 ± 1.031
1.186SerTrp: 1.186 ± 0.934
5.931SerTyr: 5.931 ± 0.097
0.0SerXaa: 0.0 ± 0.0
Thr
2.372ThrAla: 2.372 ± 0.279
1.186ThrCys: 1.186 ± 0.934
2.372ThrAsp: 2.372 ± 1.31
1.186ThrGlu: 1.186 ± 0.934
0.0ThrPhe: 0.0 ± 0.0
1.186ThrGly: 1.186 ± 0.934
0.0ThrHis: 0.0 ± 0.0
3.559ThrIle: 3.559 ± 1.213
0.0ThrLys: 0.0 ± 0.0
1.186ThrLeu: 1.186 ± 0.934
2.372ThrMet: 2.372 ± 0.279
2.372ThrAsn: 2.372 ± 0.279
5.931ThrPro: 5.931 ± 1.492
1.186ThrGln: 1.186 ± 0.655
2.372ThrArg: 2.372 ± 1.31
1.186ThrSer: 1.186 ± 0.934
2.372ThrThr: 2.372 ± 0.279
5.931ThrVal: 5.931 ± 3.081
0.0ThrTrp: 0.0 ± 0.0
1.186ThrTyr: 1.186 ± 0.655
0.0ThrXaa: 0.0 ± 0.0
Val
3.559ValAla: 3.559 ± 0.376
0.0ValCys: 0.0 ± 0.0
1.186ValAsp: 1.186 ± 0.934
7.117ValGlu: 7.117 ± 0.752
3.559ValPhe: 3.559 ± 0.376
9.49ValGly: 9.49 ± 2.705
1.186ValHis: 1.186 ± 0.655
4.745ValIle: 4.745 ± 0.558
11.862ValLys: 11.862 ± 0.194
7.117ValLeu: 7.117 ± 0.837
4.745ValMet: 4.745 ± 1.428
3.559ValAsn: 3.559 ± 0.376
2.372ValPro: 2.372 ± 0.279
8.304ValGln: 8.304 ± 1.771
5.931ValArg: 5.931 ± 1.686
7.117ValSer: 7.117 ± 2.342
1.186ValThr: 1.186 ± 0.655
10.676ValVal: 10.676 ± 0.461
2.372ValTrp: 2.372 ± 1.31
5.931ValTyr: 5.931 ± 1.686
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.186TrpAsp: 1.186 ± 0.934
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.186TrpHis: 1.186 ± 0.655
0.0TrpIle: 0.0 ± 0.0
1.186TrpLys: 1.186 ± 0.934
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.186TrpAsn: 1.186 ± 0.655
0.0TrpPro: 0.0 ± 0.0
2.372TrpGln: 2.372 ± 0.279
2.372TrpArg: 2.372 ± 0.279
2.372TrpSer: 2.372 ± 0.279
2.372TrpThr: 2.372 ± 1.868
3.559TrpVal: 3.559 ± 1.213
1.186TrpTrp: 1.186 ± 0.934
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.372TyrAla: 2.372 ± 0.279
1.186TyrCys: 1.186 ± 0.934
3.559TyrAsp: 3.559 ± 0.376
5.931TyrGlu: 5.931 ± 0.097
0.0TyrPhe: 0.0 ± 0.0
3.559TyrGly: 3.559 ± 0.376
2.372TyrHis: 2.372 ± 1.31
1.186TyrIle: 1.186 ± 0.934
2.372TyrLys: 2.372 ± 1.31
7.117TyrLeu: 7.117 ± 0.837
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.372TyrPro: 2.372 ± 1.31
3.559TyrGln: 3.559 ± 0.376
1.186TyrArg: 1.186 ± 0.934
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
7.117TyrVal: 7.117 ± 2.342
3.559TyrTrp: 3.559 ± 0.376
2.372TyrTyr: 2.372 ± 1.31
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (844 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski