Amino acid dipepetide frequency for Kordiimonas lacus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.938AlaAla: 12.938 ± 0.151	1.054AlaCys: 1.054 ± 0.03	7.286AlaAsp: 7.286 ± 0.099	6.993AlaGlu: 6.993 ± 0.1	4.561AlaPhe: 4.561 ± 0.065	9.226AlaGly: 9.226 ± 0.104	2.15AlaHis: 2.15 ± 0.043	5.651AlaIle: 5.651 ± 0.075	4.62AlaLys: 4.62 ± 0.064	11.234AlaLeu: 11.234 ± 0.109	3.244AlaMet: 3.244 ± 0.066	3.027AlaAsn: 3.027 ± 0.05	4.459AlaPro: 4.459 ± 0.074	3.414AlaGln: 3.414 ± 0.054	6.235AlaArg: 6.235 ± 0.081	5.917AlaSer: 5.917 ± 0.086	5.399AlaThr: 5.399 ± 0.079	7.671AlaVal: 7.671 ± 0.083	1.292AlaTrp: 1.292 ± 0.041	2.751AlaTyr: 2.751 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.836CysAla: 0.836 ± 0.026	0.118CysCys: 0.118 ± 0.011	0.572CysAsp: 0.572 ± 0.024	0.42CysGlu: 0.42 ± 0.02	0.352CysPhe: 0.352 ± 0.017	0.851CysGly: 0.851 ± 0.025	0.265CysHis: 0.265 ± 0.018	0.38CysIle: 0.38 ± 0.017	0.255CysLys: 0.255 ± 0.015	0.854CysLeu: 0.854 ± 0.029	0.2CysMet: 0.2 ± 0.015	0.216CysAsn: 0.216 ± 0.015	0.441CysPro: 0.441 ± 0.018	0.248CysGln: 0.248 ± 0.015	0.514CysArg: 0.514 ± 0.023	0.488CysSer: 0.488 ± 0.022	0.401CysThr: 0.401 ± 0.018	0.568CysVal: 0.568 ± 0.026	0.114CysTrp: 0.114 ± 0.009	0.219CysTyr: 0.219 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.905AspAla: 6.905 ± 0.088	0.514AspCys: 0.514 ± 0.021	4.23AspAsp: 4.23 ± 0.099	3.964AspGlu: 3.964 ± 0.07	2.77AspPhe: 2.77 ± 0.05	5.97AspGly: 5.97 ± 0.111	1.462AspHis: 1.462 ± 0.039	3.715AspIle: 3.715 ± 0.06	2.503AspLys: 2.503 ± 0.049	6.113AspLeu: 6.113 ± 0.086	2.013AspMet: 2.013 ± 0.038	1.7AspAsn: 1.7 ± 0.041	2.939AspPro: 2.939 ± 0.052	2.055AspGln: 2.055 ± 0.041	3.868AspArg: 3.868 ± 0.058	2.615AspSer: 2.615 ± 0.053	3.445AspThr: 3.445 ± 0.086	4.715AspVal: 4.715 ± 0.064	1.049AspTrp: 1.049 ± 0.036	1.927AspTyr: 1.927 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	7.877GluAla: 7.877 ± 0.108	0.421GluCys: 0.421 ± 0.021	3.792GluAsp: 3.792 ± 0.055	4.274GluGlu: 4.274 ± 0.084	2.14GluPhe: 2.14 ± 0.043	5.109GluGly: 5.109 ± 0.064	1.3GluHis: 1.3 ± 0.029	3.496GluIle: 3.496 ± 0.057	3.314GluLys: 3.314 ± 0.059	5.497GluLeu: 5.497 ± 0.074	1.851GluMet: 1.851 ± 0.041	2.103GluAsn: 2.103 ± 0.049	2.297GluPro: 2.297 ± 0.043	2.217GluGln: 2.217 ± 0.048	4.069GluArg: 4.069 ± 0.076	2.644GluSer: 2.644 ± 0.052	3.573GluThr: 3.573 ± 0.053	4.128GluVal: 4.128 ± 0.068	0.756GluTrp: 0.756 ± 0.023	1.312GluTyr: 1.312 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.999PheAla: 3.999 ± 0.064	0.378PheCys: 0.378 ± 0.019	2.991PheAsp: 2.991 ± 0.055	2.79PheGlu: 2.79 ± 0.049	1.665PhePhe: 1.665 ± 0.045	3.833PheGly: 3.833 ± 0.061	0.814PheHis: 0.814 ± 0.026	2.053PheIle: 2.053 ± 0.046	1.639PheLys: 1.639 ± 0.042	3.86PheLeu: 3.86 ± 0.064	1.148PheMet: 1.148 ± 0.03	1.276PheAsn: 1.276 ± 0.033	1.624PhePro: 1.624 ± 0.035	1.108PheGln: 1.108 ± 0.032	2.097PheArg: 2.097 ± 0.042	2.542PheSer: 2.542 ± 0.047	2.358PheThr: 2.358 ± 0.051	2.771PheVal: 2.771 ± 0.053	0.576PheTrp: 0.576 ± 0.025	1.212PheTyr: 1.212 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	8.346GlyAla: 8.346 ± 0.107	0.751GlyCys: 0.751 ± 0.028	5.421GlyAsp: 5.421 ± 0.117	4.818GlyGlu: 4.818 ± 0.065	3.86GlyPhe: 3.86 ± 0.076	7.329GlyGly: 7.329 ± 0.142	1.882GlyHis: 1.882 ± 0.042	4.45GlyIle: 4.45 ± 0.067	3.889GlyLys: 3.889 ± 0.067	8.393GlyLeu: 8.393 ± 0.087	2.481GlyMet: 2.481 ± 0.05	2.642GlyAsn: 2.642 ± 0.072	3.006GlyPro: 3.006 ± 0.046	2.908GlyGln: 2.908 ± 0.055	4.921GlyArg: 4.921 ± 0.074	4.507GlySer: 4.507 ± 0.078	4.863GlyThr: 4.863 ± 0.084	5.943GlyVal: 5.943 ± 0.085	1.251GlyTrp: 1.251 ± 0.035	2.502GlyTyr: 2.502 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.094HisAla: 2.094 ± 0.047	0.221HisCys: 0.221 ± 0.013	1.193HisAsp: 1.193 ± 0.032	1.19HisGlu: 1.19 ± 0.031	0.964HisPhe: 0.964 ± 0.028	1.738HisGly: 1.738 ± 0.038	0.552HisHis: 0.552 ± 0.023	1.196HisIle: 1.196 ± 0.032	0.881HisLys: 0.881 ± 0.029	2.085HisLeu: 2.085 ± 0.045	0.687HisMet: 0.687 ± 0.025	0.577HisAsn: 0.577 ± 0.022	1.19HisPro: 1.19 ± 0.03	0.662HisGln: 0.662 ± 0.025	1.22HisArg: 1.22 ± 0.034	1.042HisSer: 1.042 ± 0.028	1.034HisThr: 1.034 ± 0.027	1.506HisVal: 1.506 ± 0.034	0.347HisTrp: 0.347 ± 0.017	0.665HisTyr: 0.665 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.855IleAla: 5.855 ± 0.08	0.519IleCys: 0.519 ± 0.023	3.739IleAsp: 3.739 ± 0.059	3.619IleGlu: 3.619 ± 0.063	1.945IlePhe: 1.945 ± 0.047	4.609IleGly: 4.609 ± 0.063	1.076IleHis: 1.076 ± 0.032	2.643IleIle: 2.643 ± 0.051	2.274IleLys: 2.274 ± 0.05	4.844IleLeu: 4.844 ± 0.068	1.279IleMet: 1.279 ± 0.03	1.697IleAsn: 1.697 ± 0.041	2.174IlePro: 2.174 ± 0.043	1.505IleGln: 1.505 ± 0.039	3.067IleArg: 3.067 ± 0.043	3.299IleSer: 3.299 ± 0.056	3.13IleThr: 3.13 ± 0.061	3.729IleVal: 3.729 ± 0.069	0.645IleTrp: 0.645 ± 0.024	1.338IleTyr: 1.338 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	5.582LysAla: 5.582 ± 0.084	0.233LysCys: 0.233 ± 0.013	2.775LysAsp: 2.775 ± 0.059	2.576LysGlu: 2.576 ± 0.054	1.354LysPhe: 1.354 ± 0.033	3.508LysGly: 3.508 ± 0.057	0.917LysHis: 0.917 ± 0.026	2.215LysIle: 2.215 ± 0.046	2.344LysLys: 2.344 ± 0.053	4.228LysLeu: 4.228 ± 0.063	1.14LysMet: 1.14 ± 0.033	1.394LysAsn: 1.394 ± 0.034	2.341LysPro: 2.341 ± 0.05	1.342LysGln: 1.342 ± 0.032	2.801LysArg: 2.801 ± 0.048	2.472LysSer: 2.472 ± 0.057	2.29LysThr: 2.29 ± 0.043	3.04LysVal: 3.04 ± 0.05	0.487LysTrp: 0.487 ± 0.02	0.995LysTyr: 0.995 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	11.052LeuAla: 11.052 ± 0.113	0.806LeuCys: 0.806 ± 0.026	6.009LeuAsp: 6.009 ± 0.075	6.322LeuGlu: 6.322 ± 0.092	3.829LeuPhe: 3.829 ± 0.071	7.771LeuGly: 7.771 ± 0.094	1.769LeuHis: 1.769 ± 0.036	4.798LeuIle: 4.798 ± 0.075	5.096LeuLys: 5.096 ± 0.067	8.741LeuLeu: 8.741 ± 0.106	2.941LeuMet: 2.941 ± 0.051	2.97LeuAsn: 2.97 ± 0.047	4.919LeuPro: 4.919 ± 0.073	2.815LeuGln: 2.815 ± 0.052	5.103LeuArg: 5.103 ± 0.071	6.232LeuSer: 6.232 ± 0.085	5.694LeuThr: 5.694 ± 0.059	7.042LeuVal: 7.042 ± 0.088	1.133LeuTrp: 1.133 ± 0.033	2.469LeuTyr: 2.469 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	3.478MetAla: 3.478 ± 0.06	0.176MetCys: 0.176 ± 0.013	1.609MetAsp: 1.609 ± 0.038	1.553MetGlu: 1.553 ± 0.036	0.844MetPhe: 0.844 ± 0.027	2.221MetGly: 2.221 ± 0.046	0.518MetHis: 0.518 ± 0.02	1.473MetIle: 1.473 ± 0.038	1.436MetLys: 1.436 ± 0.035	2.712MetLeu: 2.712 ± 0.051	0.864MetMet: 0.864 ± 0.031	0.849MetAsn: 0.849 ± 0.023	1.603MetPro: 1.603 ± 0.042	0.926MetGln: 0.926 ± 0.027	1.7MetArg: 1.7 ± 0.04	1.758MetSer: 1.758 ± 0.041	2.014MetThr: 2.014 ± 0.044	2.091MetVal: 2.091 ± 0.043	0.246MetTrp: 0.246 ± 0.014	0.426MetTyr: 0.426 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.064AsnAla: 3.064 ± 0.052	0.258AsnCys: 0.258 ± 0.014	1.934AsnAsp: 1.934 ± 0.066	1.544AsnGlu: 1.544 ± 0.035	1.233AsnPhe: 1.233 ± 0.037	2.533AsnGly: 2.533 ± 0.055	0.632AsnHis: 0.632 ± 0.025	1.783AsnIle: 1.783 ± 0.042	1.194AsnLys: 1.194 ± 0.031	2.9AsnLeu: 2.9 ± 0.049	0.871AsnMet: 0.871 ± 0.027	0.917AsnAsn: 0.917 ± 0.031	1.814AsnPro: 1.814 ± 0.043	1.016AsnGln: 1.016 ± 0.026	1.821AsnArg: 1.821 ± 0.048	1.556AsnSer: 1.556 ± 0.04	1.613AsnThr: 1.613 ± 0.039	2.154AsnVal: 2.154 ± 0.049	0.518AsnTrp: 0.518 ± 0.021	0.799AsnTyr: 0.799 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	4.608ProAla: 4.608 ± 0.067	0.295ProCys: 0.295 ± 0.016	3.419ProAsp: 3.419 ± 0.06	3.787ProGlu: 3.787 ± 0.074	1.951ProPhe: 1.951 ± 0.039	3.666ProGly: 3.666 ± 0.06	1.002ProHis: 1.002 ± 0.029	2.341ProIle: 2.341 ± 0.043	2.017ProLys: 2.017 ± 0.043	4.13ProLeu: 4.13 ± 0.06	1.153ProMet: 1.153 ± 0.037	1.461ProAsn: 1.461 ± 0.037	1.615ProPro: 1.615 ± 0.044	1.329ProGln: 1.329 ± 0.035	2.005ProArg: 2.005 ± 0.044	2.443ProSer: 2.443 ± 0.046	2.498ProThr: 2.498 ± 0.049	3.827ProVal: 3.827 ± 0.062	0.58ProTrp: 0.58 ± 0.022	1.242ProTyr: 1.242 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.932GlnAla: 3.932 ± 0.063	0.235GlnCys: 0.235 ± 0.013	1.748GlnAsp: 1.748 ± 0.036	1.876GlnGlu: 1.876 ± 0.036	1.247GlnPhe: 1.247 ± 0.034	2.33GlnGly: 2.33 ± 0.044	0.676GlnHis: 0.676 ± 0.025	1.826GlnIle: 1.826 ± 0.04	1.487GlnLys: 1.487 ± 0.036	3.108GlnLeu: 3.108 ± 0.046	1.019GlnMet: 1.019 ± 0.029	0.965GlnAsn: 0.965 ± 0.03	1.447GlnPro: 1.447 ± 0.034	1.281GlnGln: 1.281 ± 0.041	1.723GlnArg: 1.723 ± 0.042	1.846GlnSer: 1.846 ± 0.039	1.74GlnThr: 1.74 ± 0.037	2.369GlnVal: 2.369 ± 0.042	0.365GlnTrp: 0.365 ± 0.018	0.793GlnTyr: 0.793 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	5.787ArgAla: 5.787 ± 0.08	0.38ArgCys: 0.38 ± 0.021	3.554ArgAsp: 3.554 ± 0.064	3.654ArgGlu: 3.654 ± 0.06	2.759ArgPhe: 2.759 ± 0.052	3.91ArgGly: 3.91 ± 0.058	1.413ArgHis: 1.413 ± 0.033	3.187ArgIle: 3.187 ± 0.052	2.558ArgLys: 2.558 ± 0.043	6.32ArgLeu: 6.32 ± 0.092	1.669ArgMet: 1.669 ± 0.038	1.687ArgAsn: 1.687 ± 0.038	2.598ArgPro: 2.598 ± 0.049	2.235ArgGln: 2.235 ± 0.044	3.892ArgArg: 3.892 ± 0.066	2.874ArgSer: 2.874 ± 0.048	3.101ArgThr: 3.101 ± 0.053	4.022ArgVal: 4.022 ± 0.051	0.774ArgTrp: 0.774 ± 0.026	1.72ArgTyr: 1.72 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.486SerAla: 5.486 ± 0.075	0.455SerCys: 0.455 ± 0.023	3.612SerAsp: 3.612 ± 0.057	3.067SerGlu: 3.067 ± 0.059	2.543SerPhe: 2.543 ± 0.055	5.329SerGly: 5.329 ± 0.09	1.188SerHis: 1.188 ± 0.031	2.846SerIle: 2.846 ± 0.062	2.062SerLys: 2.062 ± 0.04	5.708SerLeu: 5.708 ± 0.071	1.487SerMet: 1.487 ± 0.039	1.689SerAsn: 1.689 ± 0.05	2.424SerPro: 2.424 ± 0.051	1.681SerGln: 1.681 ± 0.044	3.129SerArg: 3.129 ± 0.054	3.006SerSer: 3.006 ± 0.054	2.737SerThr: 2.737 ± 0.047	4.162SerVal: 4.162 ± 0.054	0.709SerTrp: 0.709 ± 0.023	1.656SerTyr: 1.656 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.692ThrAla: 5.692 ± 0.084	0.453ThrCys: 0.453 ± 0.02	3.532ThrAsp: 3.532 ± 0.058	3.091ThrGlu: 3.091 ± 0.05	2.264ThrPhe: 2.264 ± 0.054	5.184ThrGly: 5.184 ± 0.07	1.093ThrHis: 1.093 ± 0.032	3.149ThrIle: 3.149 ± 0.067	2.022ThrLys: 2.022 ± 0.043	5.997ThrLeu: 5.997 ± 0.079	1.346ThrMet: 1.346 ± 0.037	1.593ThrAsn: 1.593 ± 0.044	3.102ThrPro: 3.102 ± 0.052	1.51ThrGln: 1.51 ± 0.038	2.774ThrArg: 2.774 ± 0.05	3.031ThrSer: 3.031 ± 0.051	2.722ThrThr: 2.722 ± 0.047	4.372ThrVal: 4.372 ± 0.093	0.634ThrTrp: 0.634 ± 0.025	1.442ThrTyr: 1.442 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	7.92ValAla: 7.92 ± 0.1	0.677ValCys: 0.677 ± 0.026	4.558ValAsp: 4.558 ± 0.076	4.43ValGlu: 4.43 ± 0.063	2.703ValPhe: 2.703 ± 0.052	5.645ValGly: 5.645 ± 0.077	1.314ValHis: 1.314 ± 0.032	3.95ValIle: 3.95 ± 0.075	2.999ValLys: 2.999 ± 0.051	6.649ValLeu: 6.649 ± 0.085	2.053ValMet: 2.053 ± 0.048	2.235ValAsn: 2.235 ± 0.047	3.656ValPro: 3.656 ± 0.052	2.137ValGln: 2.137 ± 0.045	4.255ValArg: 4.255 ± 0.062	4.483ValSer: 4.483 ± 0.07	4.516ValThr: 4.516 ± 0.076	5.238ValVal: 5.238 ± 0.076	0.907ValTrp: 0.907 ± 0.029	1.68ValTyr: 1.68 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.204TrpAla: 1.204 ± 0.036	0.113TrpCys: 0.113 ± 0.009	0.688TrpAsp: 0.688 ± 0.024	0.599TrpGlu: 0.599 ± 0.022	0.537TrpPhe: 0.537 ± 0.02	0.943TrpGly: 0.943 ± 0.032	0.373TrpHis: 0.373 ± 0.016	0.62TrpIle: 0.62 ± 0.023	0.484TrpLys: 0.484 ± 0.021	1.496TrpLeu: 1.496 ± 0.044	0.397TrpMet: 0.397 ± 0.021	0.409TrpAsn: 0.409 ± 0.019	0.639TrpPro: 0.639 ± 0.024	0.679TrpGln: 0.679 ± 0.025	1.04TrpArg: 1.04 ± 0.029	0.729TrpSer: 0.729 ± 0.029	0.647TrpThr: 0.647 ± 0.025	0.868TrpVal: 0.868 ± 0.029	0.228TrpTrp: 0.228 ± 0.015	0.334TrpTyr: 0.334 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.467TyrAla: 2.467 ± 0.05	0.252TyrCys: 0.252 ± 0.014	1.81TyrAsp: 1.81 ± 0.047	1.605TyrGlu: 1.605 ± 0.041	1.215TyrPhe: 1.215 ± 0.032	2.458TyrGly: 2.458 ± 0.045	0.648TyrHis: 0.648 ± 0.023	1.216TyrIle: 1.216 ± 0.03	0.959TyrLys: 0.959 ± 0.027	2.645TyrLeu: 2.645 ± 0.052	0.651TyrMet: 0.651 ± 0.021	0.749TyrAsn: 0.749 ± 0.023	1.08TyrPro: 1.08 ± 0.032	0.946TyrGln: 0.946 ± 0.028	1.859TyrArg: 1.859 ± 0.039	1.494TyrSer: 1.494 ± 0.037	1.228TyrThr: 1.228 ± 0.032	1.783TyrVal: 1.783 ± 0.038	0.416TyrTrp: 0.416 ± 0.018	0.834TyrTyr: 0.834 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3653 proteins (1205558 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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