Amino acid dipepetide frequency for Agromyces atrinae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.793AlaAla: 19.793 ± 0.187
0.65AlaCys: 0.65 ± 0.026
8.438AlaAsp: 8.438 ± 0.086
8.407AlaGlu: 8.407 ± 0.108
4.195AlaPhe: 4.195 ± 0.062
11.837AlaGly: 11.837 ± 0.112
2.402AlaHis: 2.402 ± 0.051
6.371AlaIle: 6.371 ± 0.078
2.349AlaLys: 2.349 ± 0.066
14.584AlaLeu: 14.584 ± 0.139
2.293AlaMet: 2.293 ± 0.049
2.378AlaAsn: 2.378 ± 0.046
6.542AlaPro: 6.542 ± 0.109
2.996AlaGln: 2.996 ± 0.051
9.378AlaArg: 9.378 ± 0.122
7.978AlaSer: 7.978 ± 0.091
7.676AlaThr: 7.676 ± 0.109
11.723AlaVal: 11.723 ± 0.128
1.937AlaTrp: 1.937 ± 0.044
2.299AlaTyr: 2.299 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
0.596CysAla: 0.596 ± 0.026
0.042CysCys: 0.042 ± 0.006
0.28CysAsp: 0.28 ± 0.016
0.207CysGlu: 0.207 ± 0.014
0.148CysPhe: 0.148 ± 0.012
0.489CysGly: 0.489 ± 0.022
0.105CysHis: 0.105 ± 0.01
0.218CysIle: 0.218 ± 0.013
0.059CysLys: 0.059 ± 0.007
0.373CysLeu: 0.373 ± 0.017
0.069CysMet: 0.069 ± 0.009
0.103CysAsn: 0.103 ± 0.01
0.281CysPro: 0.281 ± 0.017
0.097CysGln: 0.097 ± 0.01
0.293CysArg: 0.293 ± 0.018
0.333CysSer: 0.333 ± 0.018
0.29CysThr: 0.29 ± 0.016
0.373CysVal: 0.373 ± 0.016
0.07CysTrp: 0.07 ± 0.008
0.089CysTyr: 0.089 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
9.42AspAla: 9.42 ± 0.102
0.222AspCys: 0.222 ± 0.015
5.13AspAsp: 5.13 ± 0.092
4.807AspGlu: 4.807 ± 0.077
1.875AspPhe: 1.875 ± 0.051
6.261AspGly: 6.261 ± 0.11
1.112AspHis: 1.112 ± 0.029
2.672AspIle: 2.672 ± 0.049
0.793AspLys: 0.793 ± 0.03
6.228AspLeu: 6.228 ± 0.092
0.746AspMet: 0.746 ± 0.028
0.955AspAsn: 0.955 ± 0.036
3.903AspPro: 3.903 ± 0.05
1.313AspGln: 1.313 ± 0.038
4.567AspArg: 4.567 ± 0.082
3.135AspSer: 3.135 ± 0.059
2.874AspThr: 2.874 ± 0.057
5.871AspVal: 5.871 ± 0.074
0.934AspTrp: 0.934 ± 0.033
1.413AspTyr: 1.413 ± 0.039
0.0AspXaa: 0.0 ± 0.0
Glu
7.117GluAla: 7.117 ± 0.096
0.248GluCys: 0.248 ± 0.017
2.037GluAsp: 2.037 ± 0.053
2.551GluGlu: 2.551 ± 0.06
1.978GluPhe: 1.978 ± 0.044
4.042GluGly: 4.042 ± 0.056
1.434GluHis: 1.434 ± 0.043
3.062GluIle: 3.062 ± 0.055
1.436GluLys: 1.436 ± 0.042
6.822GluLeu: 6.822 ± 0.09
0.832GluMet: 0.832 ± 0.028
1.421GluAsn: 1.421 ± 0.04
3.189GluPro: 3.189 ± 0.069
1.953GluGln: 1.953 ± 0.041
5.57GluArg: 5.57 ± 0.099
3.701GluSer: 3.701 ± 0.056
3.292GluThr: 3.292 ± 0.071
4.283GluVal: 4.283 ± 0.07
1.009GluTrp: 1.009 ± 0.029
1.245GluTyr: 1.245 ± 0.041
0.0GluXaa: 0.0 ± 0.0
Phe
4.59PheAla: 4.59 ± 0.063
0.155PheCys: 0.155 ± 0.013
2.552PheAsp: 2.552 ± 0.043
1.934PheGlu: 1.934 ± 0.048
1.184PhePhe: 1.184 ± 0.033
3.574PheGly: 3.574 ± 0.071
0.568PheHis: 0.568 ± 0.023
1.346PheIle: 1.346 ± 0.041
0.379PheLys: 0.379 ± 0.02
2.96PheLeu: 2.96 ± 0.062
0.437PheMet: 0.437 ± 0.018
0.679PheAsn: 0.679 ± 0.027
1.385PhePro: 1.385 ± 0.031
0.745PheGln: 0.745 ± 0.028
1.87PheArg: 1.87 ± 0.045
2.02PheSer: 2.02 ± 0.047
2.286PheThr: 2.286 ± 0.054
3.031PheVal: 3.031 ± 0.048
0.524PheTrp: 0.524 ± 0.024
0.705PheTyr: 0.705 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
10.956GlyAla: 10.956 ± 0.137
0.511GlyCys: 0.511 ± 0.023
5.46GlyAsp: 5.46 ± 0.1
5.258GlyGlu: 5.258 ± 0.072
3.4GlyPhe: 3.4 ± 0.052
7.613GlyGly: 7.613 ± 0.128
1.661GlyHis: 1.661 ± 0.04
4.948GlyIle: 4.948 ± 0.07
1.734GlyLys: 1.734 ± 0.047
8.886GlyLeu: 8.886 ± 0.111
1.622GlyMet: 1.622 ± 0.042
1.767GlyAsn: 1.767 ± 0.051
3.588GlyPro: 3.588 ± 0.064
2.175GlyGln: 2.175 ± 0.048
6.237GlyArg: 6.237 ± 0.082
5.706GlySer: 5.706 ± 0.093
5.579GlyThr: 5.579 ± 0.086
8.033GlyVal: 8.033 ± 0.084
1.499GlyTrp: 1.499 ± 0.037
2.156GlyTyr: 2.156 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
2.275HisAla: 2.275 ± 0.05
0.099HisCys: 0.099 ± 0.009
1.381HisAsp: 1.381 ± 0.032
1.118HisGlu: 1.118 ± 0.032
0.573HisPhe: 0.573 ± 0.022
1.857HisGly: 1.857 ± 0.046
0.489HisHis: 0.489 ± 0.023
0.717HisIle: 0.717 ± 0.029
0.212HisLys: 0.212 ± 0.014
1.87HisLeu: 1.87 ± 0.045
0.269HisMet: 0.269 ± 0.014
0.322HisAsn: 0.322 ± 0.017
1.329HisPro: 1.329 ± 0.04
0.392HisGln: 0.392 ± 0.019
1.5HisArg: 1.5 ± 0.038
1.034HisSer: 1.034 ± 0.032
0.922HisThr: 0.922 ± 0.032
1.685HisVal: 1.685 ± 0.04
0.274HisTrp: 0.274 ± 0.014
0.427HisTyr: 0.427 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
7.755IleAla: 7.755 ± 0.087
0.23IleCys: 0.23 ± 0.015
4.085IleAsp: 4.085 ± 0.063
3.265IleGlu: 3.265 ± 0.055
1.297IlePhe: 1.297 ± 0.037
5.08IleGly: 5.08 ± 0.08
0.711IleHis: 0.711 ± 0.027
2.078IleIle: 2.078 ± 0.048
0.666IleLys: 0.666 ± 0.028
3.862IleLeu: 3.862 ± 0.072
0.615IleMet: 0.615 ± 0.022
0.889IleAsn: 0.889 ± 0.029
2.398IlePro: 2.398 ± 0.042
0.867IleGln: 0.867 ± 0.025
2.74IleArg: 2.74 ± 0.053
2.498IleSer: 2.498 ± 0.046
2.98IleThr: 2.98 ± 0.059
5.407IleVal: 5.407 ± 0.084
0.523IleTrp: 0.523 ± 0.022
0.793IleTyr: 0.793 ± 0.03
0.0IleXaa: 0.0 ± 0.0
Lys
2.04LysAla: 2.04 ± 0.06
0.051LysCys: 0.051 ± 0.007
0.86LysAsp: 0.86 ± 0.031
0.768LysGlu: 0.768 ± 0.03
0.481LysPhe: 0.481 ± 0.02
1.326LysGly: 1.326 ± 0.041
0.414LysHis: 0.414 ± 0.021
0.842LysIle: 0.842 ± 0.029
0.719LysLys: 0.719 ± 0.033
1.788LysLeu: 1.788 ± 0.041
0.312LysMet: 0.312 ± 0.018
0.523LysAsn: 0.523 ± 0.022
1.149LysPro: 1.149 ± 0.031
0.603LysGln: 0.603 ± 0.022
1.5LysArg: 1.5 ± 0.043
1.079LysSer: 1.079 ± 0.036
1.195LysThr: 1.195 ± 0.034
1.385LysVal: 1.385 ± 0.042
0.25LysTrp: 0.25 ± 0.019
0.425LysTyr: 0.425 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
15.001LeuAla: 15.001 ± 0.139
0.42LeuCys: 0.42 ± 0.021
7.262LeuAsp: 7.262 ± 0.1
5.358LeuGlu: 5.358 ± 0.08
2.907LeuPhe: 2.907 ± 0.058
9.531LeuGly: 9.531 ± 0.101
1.745LeuHis: 1.745 ± 0.035
4.601LeuIle: 4.601 ± 0.082
1.532LeuLys: 1.532 ± 0.044
10.067LeuLeu: 10.067 ± 0.134
1.346LeuMet: 1.346 ± 0.037
1.661LeuAsn: 1.661 ± 0.049
5.468LeuPro: 5.468 ± 0.071
2.163LeuGln: 2.163 ± 0.045
6.726LeuArg: 6.726 ± 0.103
6.171LeuSer: 6.171 ± 0.073
6.211LeuThr: 6.211 ± 0.08
9.942LeuVal: 9.942 ± 0.107
1.197LeuTrp: 1.197 ± 0.034
1.715LeuTyr: 1.715 ± 0.038
0.0LeuXaa: 0.0 ± 0.0
Met
1.706MetAla: 1.706 ± 0.046
0.071MetCys: 0.071 ± 0.008
0.644MetAsp: 0.644 ± 0.026
0.488MetGlu: 0.488 ± 0.022
0.451MetPhe: 0.451 ± 0.024
1.074MetGly: 1.074 ± 0.031
0.309MetHis: 0.309 ± 0.016
0.827MetIle: 0.827 ± 0.029
0.383MetLys: 0.383 ± 0.017
1.615MetLeu: 1.615 ± 0.046
0.278MetMet: 0.278 ± 0.015
0.47MetAsn: 0.47 ± 0.021
1.048MetPro: 1.048 ± 0.03
0.463MetGln: 0.463 ± 0.025
1.212MetArg: 1.212 ± 0.036
1.346MetSer: 1.346 ± 0.039
1.668MetThr: 1.668 ± 0.038
1.086MetVal: 1.086 ± 0.031
0.17MetTrp: 0.17 ± 0.012
0.271MetTyr: 0.271 ± 0.018
0.0MetXaa: 0.0 ± 0.0
Asn
2.522AsnAla: 2.522 ± 0.057
0.098AsnCys: 0.098 ± 0.01
1.241AsnAsp: 1.241 ± 0.037
1.055AsnGlu: 1.055 ± 0.034
0.629AsnPhe: 0.629 ± 0.028
2.005AsnGly: 2.005 ± 0.051
0.36AsnHis: 0.36 ± 0.018
0.902AsnIle: 0.902 ± 0.035
0.377AsnLys: 0.377 ± 0.019
1.889AsnLeu: 1.889 ± 0.046
0.296AsnMet: 0.296 ± 0.017
0.484AsnAsn: 0.484 ± 0.027
1.566AsnPro: 1.566 ± 0.045
0.506AsnGln: 0.506 ± 0.024
1.355AsnArg: 1.355 ± 0.04
1.051AsnSer: 1.051 ± 0.033
1.157AsnThr: 1.157 ± 0.04
1.679AsnVal: 1.679 ± 0.043
0.308AsnTrp: 0.308 ± 0.019
0.484AsnTyr: 0.484 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
7.025ProAla: 7.025 ± 0.098
0.152ProCys: 0.152 ± 0.012
3.644ProAsp: 3.644 ± 0.063
3.731ProGlu: 3.731 ± 0.064
1.747ProPhe: 1.747 ± 0.034
4.879ProGly: 4.879 ± 0.074
1.04ProHis: 1.04 ± 0.036
2.261ProIle: 2.261 ± 0.053
0.935ProLys: 0.935 ± 0.033
4.874ProLeu: 4.874 ± 0.074
0.704ProMet: 0.704 ± 0.028
1.104ProAsn: 1.104 ± 0.039
2.234ProPro: 2.234 ± 0.05
1.182ProGln: 1.182 ± 0.036
3.482ProArg: 3.482 ± 0.07
3.221ProSer: 3.221 ± 0.057
3.635ProThr: 3.635 ± 0.086
4.938ProVal: 4.938 ± 0.073
0.852ProTrp: 0.852 ± 0.026
1.056ProTyr: 1.056 ± 0.034
0.0ProXaa: 0.0 ± 0.0
Gln
2.887GlnAla: 2.887 ± 0.056
0.09GlnCys: 0.09 ± 0.009
0.935GlnAsp: 0.935 ± 0.034
0.993GlnGlu: 0.993 ± 0.034
0.897GlnPhe: 0.897 ± 0.033
1.688GlnGly: 1.688 ± 0.04
0.503GlnHis: 0.503 ± 0.022
1.288GlnIle: 1.288 ± 0.039
0.686GlnLys: 0.686 ± 0.026
2.633GlnLeu: 2.633 ± 0.051
0.415GlnMet: 0.415 ± 0.021
0.661GlnAsn: 0.661 ± 0.025
1.37GlnPro: 1.37 ± 0.036
0.912GlnGln: 0.912 ± 0.033
1.958GlnArg: 1.958 ± 0.056
1.545GlnSer: 1.545 ± 0.038
1.436GlnThr: 1.436 ± 0.036
1.903GlnVal: 1.903 ± 0.045
0.406GlnTrp: 0.406 ± 0.018
0.549GlnTyr: 0.549 ± 0.02
0.0GlnXaa: 0.0 ± 0.0
Arg
9.101ArgAla: 9.101 ± 0.106
0.28ArgCys: 0.28 ± 0.017
4.372ArgAsp: 4.372 ± 0.075
4.37ArgGlu: 4.37 ± 0.074
2.675ArgPhe: 2.675 ± 0.049
5.523ArgGly: 5.523 ± 0.083
1.475ArgHis: 1.475 ± 0.036
3.563ArgIle: 3.563 ± 0.056
1.166ArgLys: 1.166 ± 0.036
7.356ArgLeu: 7.356 ± 0.093
1.455ArgMet: 1.455 ± 0.036
1.234ArgAsn: 1.234 ± 0.038
3.572ArgPro: 3.572 ± 0.068
1.764ArgGln: 1.764 ± 0.047
6.568ArgArg: 6.568 ± 0.12
4.518ArgSer: 4.518 ± 0.085
3.996ArgThr: 3.996 ± 0.067
6.248ArgVal: 6.248 ± 0.089
1.14ArgTrp: 1.14 ± 0.036
1.518ArgTyr: 1.518 ± 0.044
0.0ArgXaa: 0.0 ± 0.0
Ser
7.569SerAla: 7.569 ± 0.096
0.281SerCys: 0.281 ± 0.015
3.579SerAsp: 3.579 ± 0.062
2.96SerGlu: 2.96 ± 0.051
2.112SerPhe: 2.112 ± 0.044
6.051SerGly: 6.051 ± 0.086
1.064SerHis: 1.064 ± 0.032
3.249SerIle: 3.249 ± 0.06
1.082SerLys: 1.082 ± 0.038
5.879SerLeu: 5.879 ± 0.07
1.172SerMet: 1.172 ± 0.037
1.227SerAsn: 1.227 ± 0.036
3.306SerPro: 3.306 ± 0.065
1.259SerGln: 1.259 ± 0.034
4.079SerArg: 4.079 ± 0.062
3.998SerSer: 3.998 ± 0.065
4.193SerThr: 4.193 ± 0.067
5.325SerVal: 5.325 ± 0.075
0.993SerTrp: 0.993 ± 0.032
1.223SerTyr: 1.223 ± 0.03
0.0SerXaa: 0.0 ± 0.0
Thr
7.682ThrAla: 7.682 ± 0.099
0.26ThrCys: 0.26 ± 0.017
3.973ThrAsp: 3.973 ± 0.073
3.254ThrGlu: 3.254 ± 0.056
1.94ThrPhe: 1.94 ± 0.042
5.786ThrGly: 5.786 ± 0.081
1.074ThrHis: 1.074 ± 0.033
3.314ThrIle: 3.314 ± 0.056
1.143ThrLys: 1.143 ± 0.036
6.181ThrLeu: 6.181 ± 0.083
0.848ThrMet: 0.848 ± 0.031
1.335ThrAsn: 1.335 ± 0.041
4.055ThrPro: 4.055 ± 0.082
1.292ThrGln: 1.292 ± 0.036
3.882ThrArg: 3.882 ± 0.066
3.56ThrSer: 3.56 ± 0.071
4.121ThrThr: 4.121 ± 0.08
5.876ThrVal: 5.876 ± 0.095
0.902ThrTrp: 0.902 ± 0.034
1.126ThrTyr: 1.126 ± 0.035
0.0ThrXaa: 0.0 ± 0.0
Val
12.167ValAla: 12.167 ± 0.147
0.443ValCys: 0.443 ± 0.022
6.306ValAsp: 6.306 ± 0.09
5.004ValGlu: 5.004 ± 0.07
3.093ValPhe: 3.093 ± 0.056
7.275ValGly: 7.275 ± 0.091
1.67ValHis: 1.67 ± 0.037
4.993ValIle: 4.993 ± 0.074
1.452ValLys: 1.452 ± 0.041
9.245ValLeu: 9.245 ± 0.119
1.306ValMet: 1.306 ± 0.034
1.808ValAsn: 1.808 ± 0.045
4.61ValPro: 4.61 ± 0.066
2.055ValGln: 2.055 ± 0.04
6.031ValArg: 6.031 ± 0.084
5.455ValSer: 5.455 ± 0.069
5.934ValThr: 5.934 ± 0.095
9.421ValVal: 9.421 ± 0.119
1.164ValTrp: 1.164 ± 0.034
1.604ValTyr: 1.604 ± 0.042
0.0ValXaa: 0.0 ± 0.0
Trp
1.585TrpAla: 1.585 ± 0.04
0.092TrpCys: 0.092 ± 0.01
0.719TrpAsp: 0.719 ± 0.027
0.622TrpGlu: 0.622 ± 0.025
0.591TrpPhe: 0.591 ± 0.022
1.035TrpGly: 1.035 ± 0.035
0.32TrpHis: 0.32 ± 0.014
0.774TrpIle: 0.774 ± 0.026
0.297TrpLys: 0.297 ± 0.016
1.747TrpLeu: 1.747 ± 0.043
0.309TrpMet: 0.309 ± 0.016
0.471TrpAsn: 0.471 ± 0.024
0.728TrpPro: 0.728 ± 0.025
0.523TrpGln: 0.523 ± 0.024
1.203TrpArg: 1.203 ± 0.038
1.038TrpSer: 1.038 ± 0.035
0.933TrpThr: 0.933 ± 0.032
1.195TrpVal: 1.195 ± 0.034
0.367TrpTrp: 0.367 ± 0.019
0.311TrpTyr: 0.311 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.437TyrAla: 2.437 ± 0.048
0.122TyrCys: 0.122 ± 0.01
1.334TyrAsp: 1.334 ± 0.035
1.068TyrGlu: 1.068 ± 0.033
0.755TyrPhe: 0.755 ± 0.028
1.863TyrGly: 1.863 ± 0.037
0.285TyrHis: 0.285 ± 0.018
0.711TyrIle: 0.711 ± 0.031
0.312TyrLys: 0.312 ± 0.02
2.168TyrLeu: 2.168 ± 0.051
0.254TyrMet: 0.254 ± 0.016
0.471TyrAsn: 0.471 ± 0.023
0.973TyrPro: 0.973 ± 0.027
0.497TyrGln: 0.497 ± 0.022
1.742TyrArg: 1.742 ± 0.049
1.213TyrSer: 1.213 ± 0.033
1.225TyrThr: 1.225 ± 0.039
1.635TyrVal: 1.635 ± 0.035
0.346TyrTrp: 0.346 ± 0.018
0.467TyrTyr: 0.467 ± 0.021
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3277 proteins (1105242 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski