Amino acid dipepetide frequency for Potato virus X (strain X3) (PVX)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.084AlaAla: 8.084 ± 6.483
1.427AlaCys: 1.427 ± 1.998
2.378AlaAsp: 2.378 ± 2.345
6.657AlaGlu: 6.657 ± 1.834
4.755AlaPhe: 4.755 ± 1.106
4.755AlaGly: 4.755 ± 2.697
1.427AlaHis: 1.427 ± 0.771
6.657AlaIle: 6.657 ± 5.21
4.28AlaLys: 4.28 ± 2.314
5.231AlaLeu: 5.231 ± 1.442
0.951AlaMet: 0.951 ± 0.514
4.755AlaAsn: 4.755 ± 1.831
2.853AlaPro: 2.853 ± 2.642
4.28AlaGln: 4.28 ± 4.072
4.755AlaArg: 4.755 ± 1.843
2.853AlaSer: 2.853 ± 3.071
7.608AlaThr: 7.608 ± 2.563
5.706AlaVal: 5.706 ± 2.495
1.427AlaTrp: 1.427 ± 0.619
3.804AlaTyr: 3.804 ± 1.383
0.0AlaXaa: 0.0 ± 0.0
Cys
1.427CysAla: 1.427 ± 1.269
0.0CysCys: 0.0 ± 0.0
0.476CysAsp: 0.476 ± 0.257
0.476CysGlu: 0.476 ± 0.257
1.427CysPhe: 1.427 ± 0.771
1.427CysGly: 1.427 ± 1.203
0.0CysHis: 0.0 ± 0.0
0.951CysIle: 0.951 ± 0.514
0.951CysLys: 0.951 ± 1.521
0.0CysLeu: 0.0 ± 0.0
0.476CysMet: 0.476 ± 0.851
0.951CysAsn: 0.951 ± 0.514
0.476CysPro: 0.476 ± 0.257
1.902CysGln: 1.902 ± 0.752
0.951CysArg: 0.951 ± 0.514
0.476CysSer: 0.476 ± 0.257
0.476CysThr: 0.476 ± 0.851
2.378CysVal: 2.378 ± 1.44
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.329AspAla: 3.329 ± 1.402
0.951AspCys: 0.951 ± 0.514
0.951AspAsp: 0.951 ± 0.514
3.329AspGlu: 3.329 ± 1.42
4.28AspPhe: 4.28 ± 1.792
2.378AspGly: 2.378 ± 0.938
0.951AspHis: 0.951 ± 0.514
3.329AspIle: 3.329 ± 1.275
1.902AspLys: 1.902 ± 0.752
6.657AspLeu: 6.657 ± 1.135
0.951AspMet: 0.951 ± 0.698
0.951AspAsn: 0.951 ± 1.396
1.902AspPro: 1.902 ± 0.752
0.476AspGln: 0.476 ± 0.257
2.378AspArg: 2.378 ± 1.285
4.28AspSer: 4.28 ± 1.73
2.853AspThr: 2.853 ± 1.238
2.853AspVal: 2.853 ± 0.928
0.476AspTrp: 0.476 ± 0.257
1.902AspTyr: 1.902 ± 1.028
0.0AspXaa: 0.0 ± 0.0
Glu
6.182GluAla: 6.182 ± 2.01
0.476GluCys: 0.476 ± 0.257
4.28GluAsp: 4.28 ± 1.591
5.706GluGlu: 5.706 ± 2.255
3.329GluPhe: 3.329 ± 1.42
4.28GluGly: 4.28 ± 1.109
0.476GluHis: 0.476 ± 0.851
4.28GluIle: 4.28 ± 1.623
4.755GluLys: 4.755 ± 1.837
4.755GluLeu: 4.755 ± 1.968
2.853GluMet: 2.853 ± 1.238
1.427GluAsn: 1.427 ± 0.771
5.231GluPro: 5.231 ± 1.67
1.427GluGln: 1.427 ± 0.771
1.902GluArg: 1.902 ± 1.422
4.28GluSer: 4.28 ± 1.407
6.182GluThr: 6.182 ± 1.976
6.182GluVal: 6.182 ± 2.007
0.0GluTrp: 0.0 ± 0.0
2.378GluTyr: 2.378 ± 0.887
0.0GluXaa: 0.0 ± 0.0
Phe
4.28PheAla: 4.28 ± 2.854
0.951PheCys: 0.951 ± 0.698
4.28PheAsp: 4.28 ± 0.937
0.951PheGlu: 0.951 ± 0.721
0.951PhePhe: 0.951 ± 1.702
2.378PheGly: 2.378 ± 1.285
2.378PheHis: 2.378 ± 1.44
0.476PheIle: 0.476 ± 0.257
2.853PheLys: 2.853 ± 0.575
7.133PheLeu: 7.133 ± 3.056
0.476PheMet: 0.476 ± 0.257
0.476PheAsn: 0.476 ± 0.851
0.476PhePro: 0.476 ± 0.257
1.427PheGln: 1.427 ± 0.771
2.378PheArg: 2.378 ± 0.887
4.28PheSer: 4.28 ± 0.937
2.853PheThr: 2.853 ± 0.575
1.427PheVal: 1.427 ± 0.986
0.476PheTrp: 0.476 ± 0.257
1.902PheTyr: 1.902 ± 1.441
0.0PheXaa: 0.0 ± 0.0
Gly
3.804GlyAla: 3.804 ± 0.701
0.951GlyCys: 0.951 ± 0.721
4.28GlyAsp: 4.28 ± 1.003
2.853GlyGlu: 2.853 ± 1.503
2.378GlyPhe: 2.378 ± 0.642
3.329GlyGly: 3.329 ± 1.175
1.902GlyHis: 1.902 ± 1.038
2.378GlyIle: 2.378 ± 1.503
3.329GlyLys: 3.329 ± 1.465
5.706GlyLeu: 5.706 ± 1.288
0.476GlyMet: 0.476 ± 0.257
1.427GlyAsn: 1.427 ± 1.203
2.853GlyPro: 2.853 ± 2.298
1.902GlyGln: 1.902 ± 0.752
1.427GlyArg: 1.427 ± 0.619
4.755GlySer: 4.755 ± 1.876
6.182GlyThr: 6.182 ± 1.045
2.853GlyVal: 2.853 ± 1.343
0.476GlyTrp: 0.476 ± 0.257
0.951GlyTyr: 0.951 ± 0.721
0.0GlyXaa: 0.0 ± 0.0
His
1.427HisAla: 1.427 ± 0.69
0.951HisCys: 0.951 ± 0.698
0.476HisAsp: 0.476 ± 0.257
1.427HisGlu: 1.427 ± 0.771
1.427HisPhe: 1.427 ± 0.69
2.378HisGly: 2.378 ± 0.916
0.951HisHis: 0.951 ± 0.514
0.0HisIle: 0.0 ± 0.0
1.427HisLys: 1.427 ± 0.619
2.378HisLeu: 2.378 ± 0.887
1.427HisMet: 1.427 ± 1.536
1.902HisAsn: 1.902 ± 0.759
1.902HisPro: 1.902 ± 0.752
0.951HisGln: 0.951 ± 0.514
1.902HisArg: 1.902 ± 0.759
2.853HisSer: 2.853 ± 1.513
2.853HisThr: 2.853 ± 0.857
0.951HisVal: 0.951 ± 0.837
0.476HisTrp: 0.476 ± 0.257
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.329IleAla: 3.329 ± 3.148
0.0IleCys: 0.0 ± 0.0
2.853IleAsp: 2.853 ± 0.575
3.804IleGlu: 3.804 ± 0.75
2.853IlePhe: 2.853 ± 1.067
2.378IleGly: 2.378 ± 0.887
1.902IleHis: 1.902 ± 0.759
2.378IleIle: 2.378 ± 2.961
5.231IleLys: 5.231 ± 2.755
3.804IleLeu: 3.804 ± 2.804
2.378IleMet: 2.378 ± 0.755
0.951IleAsn: 0.951 ± 0.514
5.231IlePro: 5.231 ± 1.38
4.28IleGln: 4.28 ± 1.73
2.853IleArg: 2.853 ± 0.575
2.853IleSer: 2.853 ± 2.246
6.182IleThr: 6.182 ± 3.436
2.853IleVal: 2.853 ± 1.084
0.476IleTrp: 0.476 ± 0.851
0.951IleTyr: 0.951 ± 0.837
0.0IleXaa: 0.0 ± 0.0
Lys
5.231LysAla: 5.231 ± 1.51
0.951LysCys: 0.951 ± 0.514
3.804LysAsp: 3.804 ± 1.357
4.28LysGlu: 4.28 ± 1.377
1.427LysPhe: 1.427 ± 0.619
2.853LysGly: 2.853 ± 1.38
2.853LysHis: 2.853 ± 1.542
3.804LysIle: 3.804 ± 1.766
4.28LysLys: 4.28 ± 2.314
8.084LysLeu: 8.084 ± 2.897
0.951LysMet: 0.951 ± 0.514
1.427LysAsn: 1.427 ± 0.756
4.755LysPro: 4.755 ± 1.352
0.476LysGln: 0.476 ± 0.257
1.427LysArg: 1.427 ± 0.771
4.28LysSer: 4.28 ± 2.07
5.706LysThr: 5.706 ± 2.321
7.608LysVal: 7.608 ± 2.29
0.476LysTrp: 0.476 ± 0.257
2.853LysTyr: 2.853 ± 0.845
0.0LysXaa: 0.0 ± 0.0
Leu
5.231LeuAla: 5.231 ± 1.677
0.0LeuCys: 0.0 ± 0.0
6.182LeuAsp: 6.182 ± 1.676
5.706LeuGlu: 5.706 ± 2.76
4.28LeuPhe: 4.28 ± 0.937
5.706LeuGly: 5.706 ± 2.335
2.853LeuHis: 2.853 ± 0.99
6.182LeuIle: 6.182 ± 1.673
6.657LeuLys: 6.657 ± 1.873
8.084LeuLeu: 8.084 ± 2.861
0.476LeuMet: 0.476 ± 0.245
3.804LeuAsn: 3.804 ± 1.739
6.657LeuPro: 6.657 ± 1.739
2.853LeuGln: 2.853 ± 1.542
3.804LeuArg: 3.804 ± 1.135
6.182LeuSer: 6.182 ± 3.416
6.657LeuThr: 6.657 ± 1.221
6.182LeuVal: 6.182 ± 4.485
0.476LeuTrp: 0.476 ± 0.257
2.378LeuTyr: 2.378 ± 0.844
0.0LeuXaa: 0.0 ± 0.0
Met
1.427MetAla: 1.427 ± 0.619
0.476MetCys: 0.476 ± 0.257
0.951MetAsp: 0.951 ± 0.721
2.378MetGlu: 2.378 ± 1.44
0.951MetPhe: 0.951 ± 0.514
1.427MetGly: 1.427 ± 0.771
0.476MetHis: 0.476 ± 0.257
0.951MetIle: 0.951 ± 0.698
1.427MetLys: 1.427 ± 1.535
1.902MetLeu: 1.902 ± 0.641
0.476MetMet: 0.476 ± 0.257
0.951MetAsn: 0.951 ± 0.698
1.427MetPro: 1.427 ± 0.619
0.951MetGln: 0.951 ± 0.514
1.902MetArg: 1.902 ± 1.028
1.902MetSer: 1.902 ± 1.086
0.0MetThr: 0.0 ± 0.0
0.951MetVal: 0.951 ± 0.514
0.0MetTrp: 0.0 ± 0.0
0.476MetTyr: 0.476 ± 0.257
0.0MetXaa: 0.0 ± 0.0
Asn
4.755AsnAla: 4.755 ± 2.065
2.378AsnCys: 2.378 ± 1.285
1.902AsnAsp: 1.902 ± 0.641
1.902AsnGlu: 1.902 ± 0.641
1.902AsnPhe: 1.902 ± 0.752
1.902AsnGly: 1.902 ± 1.992
1.902AsnHis: 1.902 ± 1.674
1.902AsnIle: 1.902 ± 0.759
2.378AsnLys: 2.378 ± 1.285
0.951AsnLeu: 0.951 ± 0.837
0.476AsnMet: 0.476 ± 0.257
1.427AsnAsn: 1.427 ± 1.269
2.378AsnPro: 2.378 ± 0.755
0.951AsnGln: 0.951 ± 0.514
0.476AsnArg: 0.476 ± 0.257
3.329AsnSer: 3.329 ± 3.707
2.853AsnThr: 2.853 ± 1.325
0.951AsnVal: 0.951 ± 0.514
1.427AsnTrp: 1.427 ± 1.535
1.427AsnTyr: 1.427 ± 0.771
0.0AsnXaa: 0.0 ± 0.0
Pro
5.706ProAla: 5.706 ± 2.475
0.951ProCys: 0.951 ± 1.818
1.902ProAsp: 1.902 ± 0.791
5.231ProGlu: 5.231 ± 1.228
0.476ProPhe: 0.476 ± 0.257
2.378ProGly: 2.378 ± 0.887
1.427ProHis: 1.427 ± 2.264
3.329ProIle: 3.329 ± 1.42
5.231ProLys: 5.231 ± 2.075
2.378ProLeu: 2.378 ± 1.955
0.0ProMet: 0.0 ± 0.763
1.902ProAsn: 1.902 ± 0.759
2.853ProPro: 2.853 ± 3.071
1.902ProGln: 1.902 ± 1.028
2.853ProArg: 2.853 ± 1.067
2.378ProSer: 2.378 ± 0.755
2.853ProThr: 2.853 ± 0.575
3.804ProVal: 3.804 ± 0.881
0.476ProTrp: 0.476 ± 0.257
2.853ProTyr: 2.853 ± 0.575
0.0ProXaa: 0.0 ± 0.0
Gln
6.657GlnAla: 6.657 ± 1.522
0.476GlnCys: 0.476 ± 0.257
1.427GlnAsp: 1.427 ± 0.771
4.755GlnGlu: 4.755 ± 1.968
0.951GlnPhe: 0.951 ± 0.698
1.427GlnGly: 1.427 ± 1.269
0.0GlnHis: 0.0 ± 0.0
1.427GlnIle: 1.427 ± 0.771
1.902GlnLys: 1.902 ± 0.752
2.853GlnLeu: 2.853 ± 1.542
0.0GlnMet: 0.0 ± 0.0
0.476GlnAsn: 0.476 ± 0.257
0.951GlnPro: 0.951 ± 0.514
1.902GlnGln: 1.902 ± 1.028
0.951GlnArg: 0.951 ± 0.837
3.329GlnSer: 3.329 ± 0.617
3.804GlnThr: 3.804 ± 1.281
2.853GlnVal: 2.853 ± 1.067
0.951GlnTrp: 0.951 ± 0.514
0.951GlnTyr: 0.951 ± 0.514
0.0GlnXaa: 0.0 ± 0.0
Arg
3.804ArgAla: 3.804 ± 1.94
0.0ArgCys: 0.0 ± 0.0
2.378ArgAsp: 2.378 ± 0.844
4.28ArgGlu: 4.28 ± 2.314
0.476ArgPhe: 0.476 ± 0.257
1.902ArgGly: 1.902 ± 0.791
1.902ArgHis: 1.902 ± 1.687
2.378ArgIle: 2.378 ± 0.755
3.329ArgLys: 3.329 ± 1.42
4.755ArgLeu: 4.755 ± 1.526
0.476ArgMet: 0.476 ± 0.257
4.28ArgAsn: 4.28 ± 1.461
1.902ArgPro: 1.902 ± 0.641
2.853ArgGln: 2.853 ± 0.928
0.951ArgArg: 0.951 ± 0.514
1.427ArgSer: 1.427 ± 0.69
3.329ArgThr: 3.329 ± 1.681
0.951ArgVal: 0.951 ± 1.396
0.951ArgTrp: 0.951 ± 0.514
1.902ArgTyr: 1.902 ± 1.028
0.0ArgXaa: 0.0 ± 0.0
Ser
4.755SerAla: 4.755 ± 1.106
0.0SerCys: 0.0 ± 0.0
4.28SerAsp: 4.28 ± 2.314
2.378SerGlu: 2.378 ± 1.31
4.28SerPhe: 4.28 ± 1.453
3.804SerGly: 3.804 ± 0.75
1.902SerHis: 1.902 ± 0.759
3.804SerIle: 3.804 ± 1.537
6.182SerLys: 6.182 ± 0.971
7.608SerLeu: 7.608 ± 4.04
0.951SerMet: 0.951 ± 0.514
3.329SerAsn: 3.329 ± 1.985
1.902SerPro: 1.902 ± 1.086
2.378SerGln: 2.378 ± 0.916
4.28SerArg: 4.28 ± 2.205
2.853SerSer: 2.853 ± 1.084
4.755SerThr: 4.755 ± 3.667
2.853SerVal: 2.853 ± 1.503
0.951SerTrp: 0.951 ± 0.514
2.378SerTyr: 2.378 ± 0.887
0.0SerXaa: 0.0 ± 0.0
Thr
6.657ThrAla: 6.657 ± 3.692
1.902ThrCys: 1.902 ± 0.759
1.902ThrAsp: 1.902 ± 0.641
5.706ThrGlu: 5.706 ± 1.831
4.28ThrPhe: 4.28 ± 1.1
5.706ThrGly: 5.706 ± 2.26
2.378ThrHis: 2.378 ± 1.285
5.231ThrIle: 5.231 ± 2.581
4.755ThrLys: 4.755 ± 1.244
8.559ThrLeu: 8.559 ± 1.339
2.378ThrMet: 2.378 ± 0.61
3.329ThrAsn: 3.329 ± 2.11
3.329ThrPro: 3.329 ± 1.134
2.378ThrGln: 2.378 ± 0.755
2.378ThrArg: 2.378 ± 2.472
4.28ThrSer: 4.28 ± 1.515
7.133ThrThr: 7.133 ± 4.046
4.755ThrVal: 4.755 ± 1.523
0.476ThrTrp: 0.476 ± 0.257
1.902ThrTyr: 1.902 ± 1.506
0.0ThrXaa: 0.0 ± 0.0
Val
3.804ValAla: 3.804 ± 1.583
1.427ValCys: 1.427 ± 0.619
0.951ValAsp: 0.951 ± 0.514
5.706ValGlu: 5.706 ± 1.842
0.951ValPhe: 0.951 ± 0.514
2.378ValGly: 2.378 ± 0.938
1.427ValHis: 1.427 ± 1.537
3.804ValIle: 3.804 ± 2.752
4.755ValLys: 4.755 ± 1.151
5.231ValLeu: 5.231 ± 3.401
1.902ValMet: 1.902 ± 1.028
1.902ValAsn: 1.902 ± 1.858
3.329ValPro: 3.329 ± 1.217
1.902ValGln: 1.902 ± 1.028
5.231ValArg: 5.231 ± 1.071
4.28ValSer: 4.28 ± 1.941
4.755ValThr: 4.755 ± 2.718
3.329ValVal: 3.329 ± 2.574
1.427ValTrp: 1.427 ± 0.619
2.853ValTyr: 2.853 ± 0.99
0.0ValXaa: 0.0 ± 0.0
Trp
0.951TrpAla: 0.951 ± 0.514
0.0TrpCys: 0.0 ± 0.0
0.951TrpAsp: 0.951 ± 0.698
1.427TrpGlu: 1.427 ± 0.771
0.476TrpPhe: 0.476 ± 0.257
0.476TrpGly: 0.476 ± 0.257
0.0TrpHis: 0.0 ± 0.0
0.951TrpIle: 0.951 ± 0.514
1.427TrpLys: 1.427 ± 0.619
0.951TrpLeu: 0.951 ± 0.514
0.476TrpMet: 0.476 ± 0.851
0.951TrpAsn: 0.951 ± 0.698
0.476TrpPro: 0.476 ± 0.257
0.476TrpGln: 0.476 ± 0.851
0.476TrpArg: 0.476 ± 0.257
0.476TrpSer: 0.476 ± 0.257
0.0TrpThr: 0.0 ± 0.0
0.476TrpVal: 0.476 ± 0.257
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.804TyrAla: 3.804 ± 1.357
0.951TyrCys: 0.951 ± 0.514
0.476TyrAsp: 0.476 ± 0.257
1.427TyrGlu: 1.427 ± 0.771
0.951TyrPhe: 0.951 ± 0.514
0.951TyrGly: 0.951 ± 0.837
0.951TyrHis: 0.951 ± 0.514
3.329TyrIle: 3.329 ± 1.493
0.476TyrLys: 0.476 ± 0.257
3.329TyrLeu: 3.329 ± 1.303
2.378TyrMet: 2.378 ± 1.285
0.951TyrAsn: 0.951 ± 1.396
0.476TyrPro: 0.476 ± 0.257
2.378TyrGln: 2.378 ± 1.387
0.951TyrArg: 0.951 ± 0.837
4.28TyrSer: 4.28 ± 0.937
2.378TyrThr: 2.378 ± 0.887
1.427TyrVal: 1.427 ± 0.69
0.0TyrTrp: 0.0 ± 0.0
0.476TyrTyr: 0.476 ± 0.257
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2104 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski