Amino acid dipepetide frequency for Cladosporium cladosporioides virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.96AlaAla: 11.96 ± 2.667
2.701AlaCys: 2.701 ± 1.53
5.015AlaAsp: 5.015 ± 0.346
4.63AlaGlu: 4.63 ± 1.318
3.858AlaPhe: 3.858 ± 1.093
8.102AlaGly: 8.102 ± 1.753
1.543AlaHis: 1.543 ± 0.707
4.244AlaIle: 4.244 ± 1.177
4.244AlaLys: 4.244 ± 2.56
8.873AlaLeu: 8.873 ± 1.72
2.315AlaMet: 2.315 ± 0.966
2.701AlaAsn: 2.701 ± 0.783
7.33AlaPro: 7.33 ± 2.449
3.086AlaGln: 3.086 ± 0.839
8.488AlaArg: 8.488 ± 2.488
9.259AlaSer: 9.259 ± 2.537
8.102AlaThr: 8.102 ± 1.036
6.173AlaVal: 6.173 ± 1.794
1.543AlaTrp: 1.543 ± 0.711
1.543AlaTyr: 1.543 ± 0.636
0.0AlaXaa: 0.0 ± 0.0
Cys
0.772CysAla: 0.772 ± 0.397
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.157CysGly: 1.157 ± 0.679
0.772CysHis: 0.772 ± 0.397
0.386CysIle: 0.386 ± 0.317
0.386CysLys: 0.386 ± 0.33
1.157CysLeu: 1.157 ± 0.952
0.386CysMet: 0.386 ± 0.33
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.386CysGln: 0.386 ± 0.317
0.772CysArg: 0.772 ± 0.503
0.772CysSer: 0.772 ± 0.354
0.386CysThr: 0.386 ± 0.352
1.543CysVal: 1.543 ± 0.327
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.015AspAla: 5.015 ± 0.78
0.386AspCys: 0.386 ± 0.455
3.472AspAsp: 3.472 ± 1.311
3.472AspGlu: 3.472 ± 1.192
1.929AspPhe: 1.929 ± 0.531
5.401AspGly: 5.401 ± 2.143
0.386AspHis: 0.386 ± 0.455
2.701AspIle: 2.701 ± 1.449
1.929AspLys: 1.929 ± 0.55
5.015AspLeu: 5.015 ± 1.215
0.772AspMet: 0.772 ± 0.397
1.157AspAsn: 1.157 ± 0.585
6.173AspPro: 6.173 ± 0.853
0.386AspGln: 0.386 ± 0.455
4.244AspArg: 4.244 ± 1.459
6.559AspSer: 6.559 ± 1.003
2.701AspThr: 2.701 ± 1.074
8.488AspVal: 8.488 ± 1.651
1.157AspTrp: 1.157 ± 0.626
2.315AspTyr: 2.315 ± 0.8
0.0AspXaa: 0.0 ± 0.0
Glu
5.787GluAla: 5.787 ± 2.319
0.386GluCys: 0.386 ± 0.317
0.772GluAsp: 0.772 ± 0.634
1.929GluGlu: 1.929 ± 0.873
1.543GluPhe: 1.543 ± 0.793
1.929GluGly: 1.929 ± 0.758
1.543GluHis: 1.543 ± 0.63
0.772GluIle: 0.772 ± 0.714
2.701GluLys: 2.701 ± 1.288
5.015GluLeu: 5.015 ± 1.321
1.157GluMet: 1.157 ± 0.756
1.543GluAsn: 1.543 ± 0.327
1.929GluPro: 1.929 ± 0.725
1.157GluGln: 1.157 ± 0.625
3.858GluArg: 3.858 ± 1.631
3.858GluSer: 3.858 ± 1.185
2.315GluThr: 2.315 ± 0.463
2.315GluVal: 2.315 ± 0.8
1.543GluTrp: 1.543 ± 0.763
3.086GluTyr: 3.086 ± 0.52
0.0GluXaa: 0.0 ± 0.0
Phe
3.086PheAla: 3.086 ± 0.667
0.772PheCys: 0.772 ± 0.354
3.472PheAsp: 3.472 ± 0.587
1.543PheGlu: 1.543 ± 0.676
1.543PhePhe: 1.543 ± 0.91
4.244PheGly: 4.244 ± 1.752
0.386PheHis: 0.386 ± 0.33
1.157PheIle: 1.157 ± 0.585
0.772PheLys: 0.772 ± 0.397
3.472PheLeu: 3.472 ± 0.587
0.0PheMet: 0.0 ± 0.0
0.772PheAsn: 0.772 ± 0.355
2.315PhePro: 2.315 ± 0.978
0.0PheGln: 0.0 ± 0.0
3.086PheArg: 3.086 ± 0.839
3.858PheSer: 3.858 ± 1.175
1.929PheThr: 1.929 ± 0.526
2.701PheVal: 2.701 ± 0.636
0.0PheTrp: 0.0 ± 0.0
1.157PheTyr: 1.157 ± 0.462
0.0PheXaa: 0.0 ± 0.0
Gly
9.645GlyAla: 9.645 ± 2.227
0.772GlyCys: 0.772 ± 0.355
6.944GlyAsp: 6.944 ± 1.489
1.929GlyGlu: 1.929 ± 0.65
1.929GlyPhe: 1.929 ± 0.621
6.944GlyGly: 6.944 ± 0.72
0.772GlyHis: 0.772 ± 0.354
3.086GlyIle: 3.086 ± 0.654
3.086GlyLys: 3.086 ± 1.42
5.401GlyLeu: 5.401 ± 1.19
0.772GlyMet: 0.772 ± 0.344
2.701GlyAsn: 2.701 ± 0.783
7.33GlyPro: 7.33 ± 0.632
1.543GlyGln: 1.543 ± 1.067
8.488GlyArg: 8.488 ± 2.227
7.33GlySer: 7.33 ± 3.443
4.244GlyThr: 4.244 ± 1.124
6.173GlyVal: 6.173 ± 1.838
0.0GlyTrp: 0.0 ± 0.0
1.929GlyTyr: 1.929 ± 0.873
0.0GlyXaa: 0.0 ± 0.0
His
1.543HisAla: 1.543 ± 0.636
0.0HisCys: 0.0 ± 0.0
0.772HisAsp: 0.772 ± 0.355
1.543HisGlu: 1.543 ± 0.601
0.386HisPhe: 0.386 ± 0.352
4.244HisGly: 4.244 ± 1.835
1.543HisHis: 1.543 ± 0.637
0.772HisIle: 0.772 ± 0.397
0.772HisLys: 0.772 ± 0.661
2.701HisLeu: 2.701 ± 0.681
0.772HisMet: 0.772 ± 0.397
0.772HisAsn: 0.772 ± 0.397
2.701HisPro: 2.701 ± 1.006
0.772HisGln: 0.772 ± 0.547
1.929HisArg: 1.929 ± 1.001
1.543HisSer: 1.543 ± 0.906
0.772HisThr: 0.772 ± 0.547
1.157HisVal: 1.157 ± 0.556
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.787IleAla: 5.787 ± 2.189
0.0IleCys: 0.0 ± 0.0
2.315IleAsp: 2.315 ± 0.463
1.543IleGlu: 1.543 ± 0.636
1.157IlePhe: 1.157 ± 0.991
2.315IleGly: 2.315 ± 0.448
0.386IleHis: 0.386 ± 0.317
3.086IleIle: 3.086 ± 0.839
1.157IleLys: 1.157 ± 0.625
3.858IleLeu: 3.858 ± 0.837
1.157IleMet: 1.157 ± 0.589
1.543IleAsn: 1.543 ± 0.442
2.701IlePro: 2.701 ± 1.53
0.386IleGln: 0.386 ± 0.455
1.543IleArg: 1.543 ± 0.67
2.315IleSer: 2.315 ± 0.489
2.315IleThr: 2.315 ± 1.484
2.315IleVal: 2.315 ± 1.063
0.0IleTrp: 0.0 ± 0.0
1.157IleTyr: 1.157 ± 0.607
0.0IleXaa: 0.0 ± 0.0
Lys
4.63LysAla: 4.63 ± 2.598
0.0LysCys: 0.0 ± 0.0
1.543LysAsp: 1.543 ± 0.67
2.701LysGlu: 2.701 ± 1.107
1.157LysPhe: 1.157 ± 0.462
1.543LysGly: 1.543 ± 0.46
0.386LysHis: 0.386 ± 0.568
0.772LysIle: 0.772 ± 0.661
1.543LysLys: 1.543 ± 0.78
4.63LysLeu: 4.63 ± 1.579
1.157LysMet: 1.157 ± 0.589
0.386LysAsn: 0.386 ± 0.455
2.701LysPro: 2.701 ± 1.183
0.0LysGln: 0.0 ± 0.0
3.086LysArg: 3.086 ± 1.583
2.315LysSer: 2.315 ± 0.725
1.157LysThr: 1.157 ± 0.274
3.086LysVal: 3.086 ± 0.595
0.386LysTrp: 0.386 ± 0.33
0.386LysTyr: 0.386 ± 0.33
0.0LysXaa: 0.0 ± 0.0
Leu
10.417LeuAla: 10.417 ± 2.246
0.772LeuCys: 0.772 ± 0.703
5.015LeuAsp: 5.015 ± 1.56
4.63LeuGlu: 4.63 ± 1.335
3.086LeuPhe: 3.086 ± 0.949
3.858LeuGly: 3.858 ± 1.334
3.472LeuHis: 3.472 ± 0.742
4.63LeuIle: 4.63 ± 1.567
3.858LeuLys: 3.858 ± 2.253
8.873LeuLeu: 8.873 ± 2.35
3.472LeuMet: 3.472 ± 1.227
1.929LeuAsn: 1.929 ± 0.999
4.63LeuPro: 4.63 ± 1.118
1.543LeuGln: 1.543 ± 0.911
5.401LeuArg: 5.401 ± 0.988
10.031LeuSer: 10.031 ± 2.509
5.015LeuThr: 5.015 ± 1.274
4.63LeuVal: 4.63 ± 1.907
0.386LeuTrp: 0.386 ± 0.33
2.315LeuTyr: 2.315 ± 1.193
0.0LeuXaa: 0.0 ± 0.0
Met
3.858MetAla: 3.858 ± 1.873
0.386MetCys: 0.386 ± 0.317
0.772MetAsp: 0.772 ± 0.496
1.157MetGlu: 1.157 ± 0.607
0.0MetPhe: 0.0 ± 0.0
1.157MetGly: 1.157 ± 0.589
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.772MetLys: 0.772 ± 0.661
1.157MetLeu: 1.157 ± 0.474
0.0MetMet: 0.0 ± 0.0
0.386MetAsn: 0.386 ± 0.33
1.929MetPro: 1.929 ± 0.55
1.157MetGln: 1.157 ± 0.736
1.157MetArg: 1.157 ± 0.626
3.472MetSer: 3.472 ± 1.052
1.157MetThr: 1.157 ± 0.556
1.543MetVal: 1.543 ± 0.952
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.543AsnAla: 1.543 ± 0.636
0.0AsnCys: 0.0 ± 0.0
2.315AsnAsp: 2.315 ± 0.548
1.157AsnGlu: 1.157 ± 0.64
1.157AsnPhe: 1.157 ± 0.474
1.157AsnGly: 1.157 ± 0.625
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
1.929AsnLys: 1.929 ± 0.657
0.772AsnLeu: 0.772 ± 0.397
0.772AsnMet: 0.772 ± 0.561
0.772AsnAsn: 0.772 ± 0.354
3.472AsnPro: 3.472 ± 1.58
1.157AsnGln: 1.157 ± 0.589
0.772AsnArg: 0.772 ± 0.355
2.701AsnSer: 2.701 ± 0.816
1.543AsnThr: 1.543 ± 0.522
1.543AsnVal: 1.543 ± 0.793
0.0AsnTrp: 0.0 ± 0.0
1.157AsnTyr: 1.157 ± 0.607
0.0AsnXaa: 0.0 ± 0.0
Pro
7.716ProAla: 7.716 ± 1.991
0.386ProCys: 0.386 ± 0.352
6.559ProAsp: 6.559 ± 0.393
3.086ProGlu: 3.086 ± 1.558
2.315ProPhe: 2.315 ± 0.706
8.102ProGly: 8.102 ± 0.925
2.315ProHis: 2.315 ± 0.908
3.086ProIle: 3.086 ± 0.55
1.543ProLys: 1.543 ± 1.033
4.244ProLeu: 4.244 ± 0.674
0.386ProMet: 0.386 ± 0.352
0.0ProAsn: 0.0 ± 0.0
4.63ProPro: 4.63 ± 2.468
1.543ProGln: 1.543 ± 0.522
7.716ProArg: 7.716 ± 1.623
5.787ProSer: 5.787 ± 1.567
3.472ProThr: 3.472 ± 0.832
6.944ProVal: 6.944 ± 2.025
0.386ProTrp: 0.386 ± 0.33
0.772ProTyr: 0.772 ± 0.496
0.0ProXaa: 0.0 ± 0.0
Gln
0.772GlnAla: 0.772 ± 0.354
0.0GlnCys: 0.0 ± 0.0
0.386GlnAsp: 0.386 ± 0.568
0.772GlnGlu: 0.772 ± 0.496
0.772GlnPhe: 0.772 ± 0.397
2.701GlnGly: 2.701 ± 0.953
1.157GlnHis: 1.157 ± 0.502
0.386GlnIle: 0.386 ± 0.352
0.0GlnLys: 0.0 ± 0.0
3.858GlnLeu: 3.858 ± 1.334
0.0GlnMet: 0.0 ± 0.0
0.386GlnAsn: 0.386 ± 0.352
2.315GlnPro: 2.315 ± 0.703
0.772GlnGln: 0.772 ± 0.661
2.315GlnArg: 2.315 ± 1.07
2.315GlnSer: 2.315 ± 0.8
1.929GlnThr: 1.929 ± 1.001
0.772GlnVal: 0.772 ± 0.703
0.0GlnTrp: 0.0 ± 0.0
0.386GlnTyr: 0.386 ± 0.455
0.0GlnXaa: 0.0 ± 0.0
Arg
10.417ArgAla: 10.417 ± 0.967
0.0ArgCys: 0.0 ± 0.0
6.559ArgAsp: 6.559 ± 1.668
3.086ArgGlu: 3.086 ± 0.472
3.086ArgPhe: 3.086 ± 1.823
7.716ArgGly: 7.716 ± 0.994
2.701ArgHis: 2.701 ± 0.792
2.701ArgIle: 2.701 ± 0.653
1.543ArgLys: 1.543 ± 1.125
6.173ArgLeu: 6.173 ± 1.173
2.315ArgMet: 2.315 ± 1.066
1.157ArgAsn: 1.157 ± 0.585
4.244ArgPro: 4.244 ± 1.98
1.929ArgGln: 1.929 ± 0.455
9.645ArgArg: 9.645 ± 3.939
7.716ArgSer: 7.716 ± 2.443
4.244ArgThr: 4.244 ± 1.129
3.858ArgVal: 3.858 ± 1.483
1.157ArgTrp: 1.157 ± 0.625
1.543ArgTyr: 1.543 ± 0.753
0.0ArgXaa: 0.0 ± 0.0
Ser
7.33SerAla: 7.33 ± 1.576
0.772SerCys: 0.772 ± 0.661
6.944SerAsp: 6.944 ± 0.99
2.701SerGlu: 2.701 ± 0.681
8.102SerPhe: 8.102 ± 2.13
6.559SerGly: 6.559 ± 1.24
2.315SerHis: 2.315 ± 0.845
2.701SerIle: 2.701 ± 1.389
2.315SerLys: 2.315 ± 1.154
9.259SerLeu: 9.259 ± 1.943
1.543SerMet: 1.543 ± 0.91
2.315SerAsn: 2.315 ± 1.457
6.559SerPro: 6.559 ± 2.409
2.315SerGln: 2.315 ± 1.54
8.488SerArg: 8.488 ± 2.437
9.645SerSer: 9.645 ± 4.102
3.858SerThr: 3.858 ± 1.086
8.873SerVal: 8.873 ± 2.046
0.386SerTrp: 0.386 ± 0.568
3.086SerTyr: 3.086 ± 0.654
0.0SerXaa: 0.0 ± 0.0
Thr
4.244ThrAla: 4.244 ± 0.743
0.0ThrCys: 0.0 ± 0.0
2.701ThrAsp: 2.701 ± 0.636
1.929ThrGlu: 1.929 ± 0.669
1.543ThrPhe: 1.543 ± 0.627
6.559ThrGly: 6.559 ± 1.085
1.543ThrHis: 1.543 ± 1.094
2.701ThrIle: 2.701 ± 0.349
1.929ThrLys: 1.929 ± 0.887
4.244ThrLeu: 4.244 ± 1.126
0.772ThrMet: 0.772 ± 0.484
0.772ThrAsn: 0.772 ± 0.354
4.244ThrPro: 4.244 ± 1.218
2.315ThrGln: 2.315 ± 0.467
6.173ThrArg: 6.173 ± 1.926
6.944ThrSer: 6.944 ± 1.091
3.472ThrThr: 3.472 ± 0.637
3.472ThrVal: 3.472 ± 1.961
0.0ThrTrp: 0.0 ± 0.0
0.772ThrTyr: 0.772 ± 0.503
0.0ThrXaa: 0.0 ± 0.0
Val
6.944ValAla: 6.944 ± 1.72
1.543ValCys: 1.543 ± 0.974
6.944ValAsp: 6.944 ± 1.532
5.787ValGlu: 5.787 ± 1.383
1.929ValPhe: 1.929 ± 1.191
3.858ValGly: 3.858 ± 1.167
2.315ValHis: 2.315 ± 0.463
1.929ValIle: 1.929 ± 0.741
1.543ValLys: 1.543 ± 0.637
6.559ValLeu: 6.559 ± 1.58
1.157ValMet: 1.157 ± 0.991
4.244ValAsn: 4.244 ± 1.249
4.244ValPro: 4.244 ± 1.249
1.543ValGln: 1.543 ± 1.19
3.472ValArg: 3.472 ± 0.947
6.559ValSer: 6.559 ± 2.195
6.944ValThr: 6.944 ± 1.665
5.787ValVal: 5.787 ± 1.571
0.0ValTrp: 0.0 ± 0.0
1.157ValTyr: 1.157 ± 0.702
0.0ValXaa: 0.0 ± 0.0
Trp
1.543TrpAla: 1.543 ± 0.63
0.0TrpCys: 0.0 ± 0.0
0.386TrpAsp: 0.386 ± 0.33
0.386TrpGlu: 0.386 ± 0.352
0.386TrpPhe: 0.386 ± 0.352
1.157TrpGly: 1.157 ± 0.626
0.0TrpHis: 0.0 ± 0.0
0.772TrpIle: 0.772 ± 0.634
0.772TrpLys: 0.772 ± 0.661
0.386TrpLeu: 0.386 ± 0.33
0.386TrpMet: 0.386 ± 0.568
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.386TrpArg: 0.386 ± 0.33
0.386TrpSer: 0.386 ± 0.352
0.0TrpThr: 0.0 ± 0.0
0.386TrpVal: 0.386 ± 0.352
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.701TyrAla: 2.701 ± 0.757
0.0TyrCys: 0.0 ± 0.0
0.772TyrAsp: 0.772 ± 0.397
1.157TyrGlu: 1.157 ± 0.64
0.386TyrPhe: 0.386 ± 0.317
2.315TyrGly: 2.315 ± 0.463
1.157TyrHis: 1.157 ± 0.502
1.157TyrIle: 1.157 ± 0.274
0.772TyrLys: 0.772 ± 0.529
2.315TyrLeu: 2.315 ± 0.762
0.386TyrMet: 0.386 ± 0.352
0.772TyrAsn: 0.772 ± 0.354
1.543TyrPro: 1.543 ± 0.442
0.0TyrGln: 0.0 ± 0.0
0.772TyrArg: 0.772 ± 0.354
2.701TyrSer: 2.701 ± 1.072
0.772TyrThr: 0.772 ± 0.354
2.701TyrVal: 2.701 ± 1.485
0.386TyrTrp: 0.386 ± 0.33
0.386TyrTyr: 0.386 ± 0.33
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2593 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski