Amino acid dipepetide frequency for Candidatus Photodesmus katoptron Akat1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.534AlaAla: 3.534 ± 0.133
0.808AlaCys: 0.808 ± 0.062
2.29AlaAsp: 2.29 ± 0.099
3.066AlaGlu: 3.066 ± 0.109
2.544AlaPhe: 2.544 ± 0.1
3.373AlaGly: 3.373 ± 0.115
1.115AlaHis: 1.115 ± 0.059
6.06AlaIle: 6.06 ± 0.171
4.616AlaLys: 4.616 ± 0.132
6.492AlaLeu: 6.492 ± 0.171
1.601AlaMet: 1.601 ± 0.085
3.184AlaAsn: 3.184 ± 0.108
1.404AlaPro: 1.404 ± 0.069
2.087AlaGln: 2.087 ± 0.086
2.912AlaArg: 2.912 ± 0.107
4.091AlaSer: 4.091 ± 0.133
2.769AlaThr: 2.769 ± 0.081
3.391AlaVal: 3.391 ± 0.128
0.561AlaTrp: 0.561 ± 0.049
1.808AlaTyr: 1.808 ± 0.067
0.0AlaXaa: 0.0 ± 0.0
Cys
0.625CysAla: 0.625 ± 0.044
0.164CysCys: 0.164 ± 0.027
0.532CysAsp: 0.532 ± 0.043
0.525CysGlu: 0.525 ± 0.039
0.59CysPhe: 0.59 ± 0.046
0.736CysGly: 0.736 ± 0.055
0.282CysHis: 0.282 ± 0.035
1.118CysIle: 1.118 ± 0.076
0.757CysLys: 0.757 ± 0.063
1.126CysLeu: 1.126 ± 0.06
0.307CysMet: 0.307 ± 0.04
0.654CysAsn: 0.654 ± 0.052
0.407CysPro: 0.407 ± 0.042
0.439CysGln: 0.439 ± 0.039
0.439CysArg: 0.439 ± 0.039
0.925CysSer: 0.925 ± 0.056
0.561CysThr: 0.561 ± 0.048
0.55CysVal: 0.55 ± 0.041
0.132CysTrp: 0.132 ± 0.02
0.418CysTyr: 0.418 ± 0.035
0.0CysXaa: 0.0 ± 0.0
Asp
2.501AspAla: 2.501 ± 0.093
0.518AspCys: 0.518 ± 0.042
1.879AspAsp: 1.879 ± 0.084
2.683AspGlu: 2.683 ± 0.108
2.444AspPhe: 2.444 ± 0.103
2.494AspGly: 2.494 ± 0.101
0.783AspHis: 0.783 ± 0.049
5.431AspIle: 5.431 ± 0.129
3.455AspLys: 3.455 ± 0.094
4.742AspLeu: 4.742 ± 0.134
1.122AspMet: 1.122 ± 0.063
2.512AspAsn: 2.512 ± 0.088
1.454AspPro: 1.454 ± 0.078
1.322AspGln: 1.322 ± 0.063
2.04AspArg: 2.04 ± 0.099
3.241AspSer: 3.241 ± 0.104
2.069AspThr: 2.069 ± 0.082
2.476AspVal: 2.476 ± 0.102
0.579AspTrp: 0.579 ± 0.048
1.651AspTyr: 1.651 ± 0.086
0.0AspXaa: 0.0 ± 0.0
Glu
3.28GluAla: 3.28 ± 0.122
0.493GluCys: 0.493 ± 0.042
2.162GluAsp: 2.162 ± 0.101
3.437GluGlu: 3.437 ± 0.109
2.337GluPhe: 2.337 ± 0.084
2.762GluGly: 2.762 ± 0.102
1.229GluHis: 1.229 ± 0.058
5.599GluIle: 5.599 ± 0.148
5.37GluLys: 5.37 ± 0.15
6.635GluLeu: 6.635 ± 0.146
1.619GluMet: 1.619 ± 0.079
3.291GluAsn: 3.291 ± 0.115
1.429GluPro: 1.429 ± 0.081
2.523GluGln: 2.523 ± 0.095
2.737GluArg: 2.737 ± 0.093
3.277GluSer: 3.277 ± 0.106
2.512GluThr: 2.512 ± 0.087
3.545GluVal: 3.545 ± 0.114
0.518GluTrp: 0.518 ± 0.043
1.901GluTyr: 1.901 ± 0.089
0.0GluXaa: 0.0 ± 0.0
Phe
2.076PheAla: 2.076 ± 0.097
0.579PheCys: 0.579 ± 0.05
2.251PheAsp: 2.251 ± 0.092
2.112PheGlu: 2.112 ± 0.089
2.658PhePhe: 2.658 ± 0.102
2.973PheGly: 2.973 ± 0.106
1.076PheHis: 1.076 ± 0.065
4.613PheIle: 4.613 ± 0.151
3.066PheLys: 3.066 ± 0.093
4.856PheLeu: 4.856 ± 0.15
0.95PheMet: 0.95 ± 0.059
2.776PheAsn: 2.776 ± 0.107
1.629PhePro: 1.629 ± 0.078
1.704PheGln: 1.704 ± 0.082
1.74PheArg: 1.74 ± 0.079
4.767PheSer: 4.767 ± 0.129
2.062PheThr: 2.062 ± 0.085
2.051PheVal: 2.051 ± 0.085
0.461PheTrp: 0.461 ± 0.04
1.572PheTyr: 1.572 ± 0.079
0.0PheXaa: 0.0 ± 0.0
Gly
3.319GlyAla: 3.319 ± 0.12
0.804GlyCys: 0.804 ± 0.06
2.687GlyAsp: 2.687 ± 0.124
3.187GlyGlu: 3.187 ± 0.119
2.909GlyPhe: 2.909 ± 0.098
3.73GlyGly: 3.73 ± 0.152
1.365GlyHis: 1.365 ± 0.076
6.521GlyIle: 6.521 ± 0.149
4.984GlyLys: 4.984 ± 0.13
5.728GlyLeu: 5.728 ± 0.15
1.658GlyMet: 1.658 ± 0.075
3.119GlyAsn: 3.119 ± 0.12
1.415GlyPro: 1.415 ± 0.068
2.087GlyGln: 2.087 ± 0.078
2.751GlyArg: 2.751 ± 0.125
3.552GlySer: 3.552 ± 0.118
3.03GlyThr: 3.03 ± 0.111
3.573GlyVal: 3.573 ± 0.118
0.593GlyTrp: 0.593 ± 0.049
2.43GlyTyr: 2.43 ± 0.093
0.0GlyXaa: 0.0 ± 0.0
His
1.197HisAla: 1.197 ± 0.065
0.289HisCys: 0.289 ± 0.032
0.847HisAsp: 0.847 ± 0.056
0.893HisGlu: 0.893 ± 0.058
1.015HisPhe: 1.015 ± 0.057
1.311HisGly: 1.311 ± 0.084
0.611HisHis: 0.611 ± 0.061
2.033HisIle: 2.033 ± 0.083
1.372HisLys: 1.372 ± 0.065
2.283HisLeu: 2.283 ± 0.091
0.439HisMet: 0.439 ± 0.045
1.176HisAsn: 1.176 ± 0.057
1.004HisPro: 1.004 ± 0.057
0.804HisGln: 0.804 ± 0.054
1.029HisArg: 1.029 ± 0.062
1.658HisSer: 1.658 ± 0.078
1.0HisThr: 1.0 ± 0.072
1.158HisVal: 1.158 ± 0.066
0.247HisTrp: 0.247 ± 0.035
0.875HisTyr: 0.875 ± 0.054
0.0HisXaa: 0.0 ± 0.0
Ile
6.739IleAla: 6.739 ± 0.175
1.108IleCys: 1.108 ± 0.061
5.206IleAsp: 5.206 ± 0.145
6.239IleGlu: 6.239 ± 0.139
3.995IlePhe: 3.995 ± 0.147
6.26IleGly: 6.26 ± 0.169
2.126IleHis: 2.126 ± 0.09
9.158IleIle: 9.158 ± 0.234
7.679IleLys: 7.679 ± 0.178
9.644IleLeu: 9.644 ± 0.218
1.987IleMet: 1.987 ± 0.09
5.871IleAsn: 5.871 ± 0.164
3.934IlePro: 3.934 ± 0.126
3.888IleGln: 3.888 ± 0.126
4.463IleArg: 4.463 ± 0.147
7.943IleSer: 7.943 ± 0.168
4.981IleThr: 4.981 ± 0.133
5.035IleVal: 5.035 ± 0.132
0.836IleTrp: 0.836 ± 0.062
2.884IleTyr: 2.884 ± 0.106
0.0IleXaa: 0.0 ± 0.0
Lys
4.206LysAla: 4.206 ± 0.122
0.59LysCys: 0.59 ± 0.052
3.184LysAsp: 3.184 ± 0.113
5.049LysGlu: 5.049 ± 0.136
2.916LysPhe: 2.916 ± 0.092
3.998LysGly: 3.998 ± 0.127
1.779LysHis: 1.779 ± 0.072
8.061LysIle: 8.061 ± 0.178
8.125LysLys: 8.125 ± 0.214
7.668LysLeu: 7.668 ± 0.177
1.812LysMet: 1.812 ± 0.092
5.914LysAsn: 5.914 ± 0.179
2.319LysPro: 2.319 ± 0.092
3.48LysGln: 3.48 ± 0.129
3.419LysArg: 3.419 ± 0.107
4.945LysSer: 4.945 ± 0.122
4.07LysThr: 4.07 ± 0.13
4.591LysVal: 4.591 ± 0.139
0.604LysTrp: 0.604 ± 0.047
2.508LysTyr: 2.508 ± 0.094
0.0LysXaa: 0.0 ± 0.0
Leu
6.589LeuAla: 6.589 ± 0.163
1.161LeuCys: 1.161 ± 0.059
5.449LeuAsp: 5.449 ± 0.147
6.292LeuGlu: 6.292 ± 0.152
4.62LeuPhe: 4.62 ± 0.16
6.349LeuGly: 6.349 ± 0.141
1.947LeuHis: 1.947 ± 0.083
9.508LeuIle: 9.508 ± 0.231
8.154LeuLys: 8.154 ± 0.168
10.426LeuLeu: 10.426 ± 0.226
2.394LeuMet: 2.394 ± 0.085
6.131LeuAsn: 6.131 ± 0.154
4.073LeuPro: 4.073 ± 0.122
2.837LeuGln: 2.837 ± 0.1
4.238LeuArg: 4.238 ± 0.143
8.6LeuSer: 8.6 ± 0.204
5.356LeuThr: 5.356 ± 0.156
6.128LeuVal: 6.128 ± 0.172
0.915LeuTrp: 0.915 ± 0.066
2.841LeuTyr: 2.841 ± 0.095
0.0LeuXaa: 0.0 ± 0.0
Met
1.519MetAla: 1.519 ± 0.06
0.232MetCys: 0.232 ± 0.026
1.118MetAsp: 1.118 ± 0.062
1.215MetGlu: 1.215 ± 0.072
0.95MetPhe: 0.95 ± 0.061
1.336MetGly: 1.336 ± 0.074
0.504MetHis: 0.504 ± 0.044
2.201MetIle: 2.201 ± 0.091
1.965MetLys: 1.965 ± 0.1
2.544MetLeu: 2.544 ± 0.098
0.675MetMet: 0.675 ± 0.048
1.422MetAsn: 1.422 ± 0.067
0.922MetPro: 0.922 ± 0.056
0.9MetGln: 0.9 ± 0.056
1.168MetArg: 1.168 ± 0.062
1.779MetSer: 1.779 ± 0.073
1.265MetThr: 1.265 ± 0.069
1.411MetVal: 1.411 ± 0.064
0.118MetTrp: 0.118 ± 0.021
0.643MetTyr: 0.643 ± 0.055
0.0MetXaa: 0.0 ± 0.0
Asn
2.987AsnAla: 2.987 ± 0.1
0.761AsnCys: 0.761 ± 0.057
2.251AsnAsp: 2.251 ± 0.096
3.184AsnGlu: 3.184 ± 0.104
2.841AsnPhe: 2.841 ± 0.11
3.062AsnGly: 3.062 ± 0.098
1.454AsnHis: 1.454 ± 0.069
6.128AsnIle: 6.128 ± 0.175
4.974AsnLys: 4.974 ± 0.136
5.928AsnLeu: 5.928 ± 0.153
1.329AsnMet: 1.329 ± 0.068
3.805AsnAsn: 3.805 ± 0.135
2.19AsnPro: 2.19 ± 0.082
2.894AsnGln: 2.894 ± 0.088
2.605AsnArg: 2.605 ± 0.097
4.063AsnSer: 4.063 ± 0.127
2.873AsnThr: 2.873 ± 0.122
2.88AsnVal: 2.88 ± 0.101
0.815AsnTrp: 0.815 ± 0.057
2.194AsnTyr: 2.194 ± 0.091
0.0AsnXaa: 0.0 ± 0.0
Pro
1.626ProAla: 1.626 ± 0.073
0.354ProCys: 0.354 ± 0.033
1.604ProAsp: 1.604 ± 0.073
2.28ProGlu: 2.28 ± 0.074
1.654ProPhe: 1.654 ± 0.076
1.997ProGly: 1.997 ± 0.103
0.607ProHis: 0.607 ± 0.049
3.745ProIle: 3.745 ± 0.124
2.619ProLys: 2.619 ± 0.09
3.194ProLeu: 3.194 ± 0.128
0.75ProMet: 0.75 ± 0.055
2.151ProAsn: 2.151 ± 0.091
0.707ProPro: 0.707 ± 0.046
0.818ProGln: 0.818 ± 0.056
1.058ProArg: 1.058 ± 0.064
2.269ProSer: 2.269 ± 0.101
1.737ProThr: 1.737 ± 0.074
2.19ProVal: 2.19 ± 0.085
0.386ProTrp: 0.386 ± 0.04
1.186ProTyr: 1.186 ± 0.062
0.0ProXaa: 0.0 ± 0.0
Gln
2.369GlnAla: 2.369 ± 0.086
0.418GlnCys: 0.418 ± 0.039
1.558GlnAsp: 1.558 ± 0.07
2.19GlnGlu: 2.19 ± 0.104
1.744GlnPhe: 1.744 ± 0.078
2.13GlnGly: 2.13 ± 0.093
0.711GlnHis: 0.711 ± 0.046
3.63GlnIle: 3.63 ± 0.12
2.837GlnLys: 2.837 ± 0.1
4.216GlnLeu: 4.216 ± 0.128
0.843GlnMet: 0.843 ± 0.05
2.072GlnAsn: 2.072 ± 0.094
1.058GlnPro: 1.058 ± 0.055
1.308GlnGln: 1.308 ± 0.083
1.615GlnArg: 1.615 ± 0.077
2.358GlnSer: 2.358 ± 0.094
1.633GlnThr: 1.633 ± 0.065
2.405GlnVal: 2.405 ± 0.107
0.314GlnTrp: 0.314 ± 0.031
1.433GlnTyr: 1.433 ± 0.071
0.0GlnXaa: 0.0 ± 0.0
Arg
2.333ArgAla: 2.333 ± 0.095
0.45ArgCys: 0.45 ± 0.043
1.969ArgAsp: 1.969 ± 0.081
2.458ArgGlu: 2.458 ± 0.094
2.215ArgPhe: 2.215 ± 0.085
2.326ArgGly: 2.326 ± 0.091
0.868ArgHis: 0.868 ± 0.047
4.431ArgIle: 4.431 ± 0.136
3.387ArgLys: 3.387 ± 0.116
4.699ArgLeu: 4.699 ± 0.136
1.133ArgMet: 1.133 ± 0.055
2.594ArgAsn: 2.594 ± 0.104
1.361ArgPro: 1.361 ± 0.071
1.747ArgGln: 1.747 ± 0.081
2.262ArgArg: 2.262 ± 0.116
2.998ArgSer: 2.998 ± 0.107
2.051ArgThr: 2.051 ± 0.075
2.644ArgVal: 2.644 ± 0.105
0.479ArgTrp: 0.479 ± 0.039
1.701ArgTyr: 1.701 ± 0.085
0.0ArgXaa: 0.0 ± 0.0
Ser
4.023SerAla: 4.023 ± 0.092
0.772SerCys: 0.772 ± 0.06
3.38SerAsp: 3.38 ± 0.109
4.034SerGlu: 4.034 ± 0.138
3.43SerPhe: 3.43 ± 0.125
5.17SerGly: 5.17 ± 0.157
1.333SerHis: 1.333 ± 0.062
7.689SerIle: 7.689 ± 0.188
5.503SerLys: 5.503 ± 0.15
7.325SerLeu: 7.325 ± 0.175
1.862SerMet: 1.862 ± 0.074
4.381SerAsn: 4.381 ± 0.148
2.105SerPro: 2.105 ± 0.094
2.355SerGln: 2.355 ± 0.086
3.001SerArg: 3.001 ± 0.098
5.928SerSer: 5.928 ± 0.14
3.605SerThr: 3.605 ± 0.127
4.27SerVal: 4.27 ± 0.113
0.711SerTrp: 0.711 ± 0.055
2.448SerTyr: 2.448 ± 0.094
0.0SerXaa: 0.0 ± 0.0
Thr
3.012ThrAla: 3.012 ± 0.105
0.565ThrCys: 0.565 ± 0.043
2.251ThrAsp: 2.251 ± 0.077
2.662ThrGlu: 2.662 ± 0.098
2.23ThrPhe: 2.23 ± 0.091
3.28ThrGly: 3.28 ± 0.12
1.04ThrHis: 1.04 ± 0.06
4.72ThrIle: 4.72 ± 0.142
3.427ThrLys: 3.427 ± 0.116
5.42ThrLeu: 5.42 ± 0.14
1.022ThrMet: 1.022 ± 0.058
2.58ThrAsn: 2.58 ± 0.095
1.933ThrPro: 1.933 ± 0.079
1.744ThrGln: 1.744 ± 0.082
2.012ThrArg: 2.012 ± 0.087
3.405ThrSer: 3.405 ± 0.096
2.562ThrThr: 2.562 ± 0.11
2.912ThrVal: 2.912 ± 0.116
0.515ThrTrp: 0.515 ± 0.043
1.411ThrTyr: 1.411 ± 0.066
0.0ThrXaa: 0.0 ± 0.0
Val
3.552ValAla: 3.552 ± 0.126
0.632ValCys: 0.632 ± 0.048
2.841ValAsp: 2.841 ± 0.111
3.155ValGlu: 3.155 ± 0.116
2.701ValPhe: 2.701 ± 0.106
3.627ValGly: 3.627 ± 0.128
1.315ValHis: 1.315 ± 0.072
5.413ValIle: 5.413 ± 0.142
3.927ValLys: 3.927 ± 0.126
5.989ValLeu: 5.989 ± 0.164
1.429ValMet: 1.429 ± 0.061
3.187ValAsn: 3.187 ± 0.117
1.922ValPro: 1.922 ± 0.085
1.729ValGln: 1.729 ± 0.074
2.569ValArg: 2.569 ± 0.106
4.316ValSer: 4.316 ± 0.118
2.73ValThr: 2.73 ± 0.103
3.691ValVal: 3.691 ± 0.152
0.497ValTrp: 0.497 ± 0.046
1.704ValTyr: 1.704 ± 0.076
0.0ValXaa: 0.0 ± 0.0
Trp
0.447TrpAla: 0.447 ± 0.043
0.132TrpCys: 0.132 ± 0.022
0.411TrpAsp: 0.411 ± 0.043
0.4TrpGlu: 0.4 ± 0.039
0.493TrpPhe: 0.493 ± 0.044
0.497TrpGly: 0.497 ± 0.048
0.236TrpHis: 0.236 ± 0.027
1.025TrpIle: 1.025 ± 0.06
0.779TrpLys: 0.779 ± 0.046
1.286TrpLeu: 1.286 ± 0.086
0.229TrpMet: 0.229 ± 0.028
0.679TrpAsn: 0.679 ± 0.044
0.332TrpPro: 0.332 ± 0.036
0.422TrpGln: 0.422 ± 0.037
0.443TrpArg: 0.443 ± 0.038
0.565TrpSer: 0.565 ± 0.046
0.336TrpThr: 0.336 ± 0.034
0.479TrpVal: 0.479 ± 0.039
0.132TrpTrp: 0.132 ± 0.027
0.486TrpTyr: 0.486 ± 0.04
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.776TyrAla: 1.776 ± 0.076
0.461TyrCys: 0.461 ± 0.041
1.526TyrAsp: 1.526 ± 0.082
1.594TyrGlu: 1.594 ± 0.077
1.687TyrPhe: 1.687 ± 0.09
2.03TyrGly: 2.03 ± 0.082
0.861TyrHis: 0.861 ± 0.05
2.887TyrIle: 2.887 ± 0.115
2.24TyrLys: 2.24 ± 0.078
3.809TyrLeu: 3.809 ± 0.132
0.725TyrMet: 0.725 ± 0.049
1.719TyrAsn: 1.719 ± 0.07
1.333TyrPro: 1.333 ± 0.073
1.754TyrGln: 1.754 ± 0.071
1.604TyrArg: 1.604 ± 0.078
2.644TyrSer: 2.644 ± 0.121
1.501TyrThr: 1.501 ± 0.078
1.547TyrVal: 1.547 ± 0.077
0.397TyrTrp: 0.397 ± 0.037
1.233TyrTyr: 1.233 ± 0.065
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 853 proteins (279869 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski