Amino acid dipepetide frequency for Canis familiaris papillomavirus 17

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.491AlaAla: 3.491 ± 0.759
0.499AlaCys: 0.499 ± 0.451
1.995AlaAsp: 1.995 ± 0.976
2.993AlaGlu: 2.993 ± 1.018
4.489AlaPhe: 4.489 ± 1.805
4.489AlaGly: 4.489 ± 1.686
0.998AlaHis: 0.998 ± 0.598
1.995AlaIle: 1.995 ± 0.789
2.993AlaLys: 2.993 ± 0.773
3.99AlaLeu: 3.99 ± 1.031
1.496AlaMet: 1.496 ± 0.772
1.496AlaAsn: 1.496 ± 0.83
4.489AlaPro: 4.489 ± 1.083
2.993AlaGln: 2.993 ± 0.843
1.995AlaArg: 1.995 ± 0.85
4.988AlaSer: 4.988 ± 1.554
3.99AlaThr: 3.99 ± 2.064
3.491AlaVal: 3.491 ± 1.984
0.0AlaTrp: 0.0 ± 0.0
0.499AlaTyr: 0.499 ± 0.433
0.0AlaXaa: 0.0 ± 0.0
Cys
1.995CysAla: 1.995 ± 1.155
0.998CysCys: 0.998 ± 1.311
1.496CysAsp: 1.496 ± 0.701
0.998CysGlu: 0.998 ± 1.311
0.499CysPhe: 0.499 ± 0.405
0.499CysGly: 0.499 ± 0.656
0.998CysHis: 0.998 ± 1.412
0.998CysIle: 0.998 ± 0.727
2.494CysLys: 2.494 ± 1.735
2.993CysLeu: 2.993 ± 1.761
0.499CysMet: 0.499 ± 0.656
1.496CysAsn: 1.496 ± 1.057
0.998CysPro: 0.998 ± 0.811
0.499CysGln: 0.499 ± 0.433
1.496CysArg: 1.496 ± 0.858
1.496CysSer: 1.496 ± 0.967
0.499CysThr: 0.499 ± 0.405
0.998CysVal: 0.998 ± 1.311
0.499CysTrp: 0.499 ± 0.451
0.499CysTyr: 0.499 ± 0.405
0.0CysXaa: 0.0 ± 0.0
Asp
1.995AspAla: 1.995 ± 0.755
1.496AspCys: 1.496 ± 0.73
2.993AspAsp: 2.993 ± 1.093
5.985AspGlu: 5.985 ± 3.237
3.491AspPhe: 3.491 ± 0.815
5.486AspGly: 5.486 ± 2.155
0.0AspHis: 0.0 ± 0.0
2.494AspIle: 2.494 ± 0.735
1.995AspLys: 1.995 ± 0.826
4.489AspLeu: 4.489 ± 1.799
0.499AspMet: 0.499 ± 0.645
0.998AspAsn: 0.998 ± 0.811
6.484AspPro: 6.484 ± 2.635
1.995AspGln: 1.995 ± 0.989
2.494AspArg: 2.494 ± 1.226
3.491AspSer: 3.491 ± 0.554
3.491AspThr: 3.491 ± 0.806
5.486AspVal: 5.486 ± 2.584
0.499AspTrp: 0.499 ± 0.451
0.998AspTyr: 0.998 ± 0.497
0.0AspXaa: 0.0 ± 0.0
Glu
4.489GluAla: 4.489 ± 2.073
0.0GluCys: 0.0 ± 0.0
8.978GluAsp: 8.978 ± 4.473
5.486GluGlu: 5.486 ± 2.621
1.995GluPhe: 1.995 ± 1.425
4.489GluGly: 4.489 ± 1.512
1.496GluHis: 1.496 ± 0.809
3.491GluIle: 3.491 ± 1.489
4.489GluLys: 4.489 ± 2.056
2.993GluLeu: 2.993 ± 1.3
0.998GluMet: 0.998 ± 0.497
2.494GluAsn: 2.494 ± 1.069
3.491GluPro: 3.491 ± 0.775
2.993GluGln: 2.993 ± 1.106
3.491GluArg: 3.491 ± 1.41
4.489GluSer: 4.489 ± 1.032
3.491GluThr: 3.491 ± 1.318
3.491GluVal: 3.491 ± 1.253
0.499GluTrp: 0.499 ± 0.451
0.998GluTyr: 0.998 ± 0.471
0.0GluXaa: 0.0 ± 0.0
Phe
2.993PheAla: 2.993 ± 0.842
0.998PheCys: 0.998 ± 0.896
2.494PheAsp: 2.494 ± 0.697
1.995PheGlu: 1.995 ± 0.86
0.499PhePhe: 0.499 ± 0.405
2.993PheGly: 2.993 ± 0.759
0.998PheHis: 0.998 ± 0.797
1.496PheIle: 1.496 ± 0.864
0.499PheLys: 0.499 ± 0.405
2.993PheLeu: 2.993 ± 0.668
0.0PheMet: 0.0 ± 0.0
0.998PheAsn: 0.998 ± 0.811
1.496PhePro: 1.496 ± 0.535
0.998PheGln: 0.998 ± 0.865
0.998PheArg: 0.998 ± 0.811
1.995PheSer: 1.995 ± 0.971
1.995PheThr: 1.995 ± 0.744
2.993PheVal: 2.993 ± 1.533
0.998PheTrp: 0.998 ± 0.811
1.995PheTyr: 1.995 ± 0.936
0.0PheXaa: 0.0 ± 0.0
Gly
1.995GlyAla: 1.995 ± 0.775
1.496GlyCys: 1.496 ± 0.858
5.486GlyAsp: 5.486 ± 0.624
8.479GlyGlu: 8.479 ± 1.763
1.995GlyPhe: 1.995 ± 1.149
10.474GlyGly: 10.474 ± 3.799
1.995GlyHis: 1.995 ± 0.695
1.496GlyIle: 1.496 ± 0.978
5.486GlyLys: 5.486 ± 1.709
3.491GlyLeu: 3.491 ± 1.188
0.0GlyMet: 0.0 ± 0.0
4.489GlyAsn: 4.489 ± 1.57
4.988GlyPro: 4.988 ± 2.026
1.496GlyGln: 1.496 ± 1.352
10.973GlyArg: 10.973 ± 3.282
9.476GlySer: 9.476 ± 2.261
5.486GlyThr: 5.486 ± 2.45
4.988GlyVal: 4.988 ± 0.876
0.0GlyTrp: 0.0 ± 0.0
0.499GlyTyr: 0.499 ± 0.433
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.499HisGlu: 0.499 ± 0.405
0.998HisPhe: 0.998 ± 0.778
2.494HisGly: 2.494 ± 1.0
0.0HisHis: 0.0 ± 0.0
0.499HisIle: 0.499 ± 0.433
0.998HisLys: 0.998 ± 0.485
0.499HisLeu: 0.499 ± 0.405
0.499HisMet: 0.499 ± 0.405
0.998HisAsn: 0.998 ± 0.596
1.995HisPro: 1.995 ± 1.195
0.998HisGln: 0.998 ± 0.947
2.993HisArg: 2.993 ± 1.882
3.491HisSer: 3.491 ± 2.063
0.998HisThr: 0.998 ± 0.471
0.998HisVal: 0.998 ± 0.471
0.499HisTrp: 0.499 ± 0.405
0.998HisTyr: 0.998 ± 0.485
0.0HisXaa: 0.0 ± 0.0
Ile
1.496IleAla: 1.496 ± 0.858
0.499IleCys: 0.499 ± 0.706
0.998IleAsp: 0.998 ± 0.865
1.995IleGlu: 1.995 ± 0.943
1.496IlePhe: 1.496 ± 0.914
4.489IleGly: 4.489 ± 1.78
1.496IleHis: 1.496 ± 0.766
1.496IleIle: 1.496 ± 0.801
1.995IleLys: 1.995 ± 0.853
3.491IleLeu: 3.491 ± 0.98
0.998IleMet: 0.998 ± 0.475
0.499IleAsn: 0.499 ± 0.433
5.985IlePro: 5.985 ± 1.444
0.998IleGln: 0.998 ± 0.497
1.496IleArg: 1.496 ± 1.315
2.993IleSer: 2.993 ± 1.03
0.998IleThr: 0.998 ± 0.598
4.489IleVal: 4.489 ± 0.818
0.499IleTrp: 0.499 ± 0.405
1.995IleTyr: 1.995 ± 0.695
0.0IleXaa: 0.0 ± 0.0
Lys
1.995LysAla: 1.995 ± 0.993
0.998LysCys: 0.998 ± 0.497
3.99LysAsp: 3.99 ± 1.826
0.998LysGlu: 0.998 ± 0.596
0.499LysPhe: 0.499 ± 0.405
3.99LysGly: 3.99 ± 0.741
0.499LysHis: 0.499 ± 0.405
2.494LysIle: 2.494 ± 1.128
2.993LysLys: 2.993 ± 1.148
3.491LysLeu: 3.491 ± 1.957
0.0LysMet: 0.0 ± 0.0
2.494LysAsn: 2.494 ± 1.196
0.998LysPro: 0.998 ± 0.75
1.496LysGln: 1.496 ± 0.864
6.983LysArg: 6.983 ± 1.477
0.998LysSer: 0.998 ± 0.75
1.995LysThr: 1.995 ± 0.943
4.489LysVal: 4.489 ± 2.223
0.998LysTrp: 0.998 ± 0.596
2.494LysTyr: 2.494 ± 0.955
0.0LysXaa: 0.0 ± 0.0
Leu
3.99LeuAla: 3.99 ± 1.214
1.995LeuCys: 1.995 ± 1.985
4.988LeuAsp: 4.988 ± 1.173
6.484LeuGlu: 6.484 ± 1.599
4.489LeuPhe: 4.489 ± 1.703
5.985LeuGly: 5.985 ± 1.52
1.496LeuHis: 1.496 ± 0.386
1.995LeuIle: 1.995 ± 0.803
4.988LeuLys: 4.988 ± 1.077
4.988LeuLeu: 4.988 ± 2.269
0.499LeuMet: 0.499 ± 0.411
1.995LeuAsn: 1.995 ± 0.695
2.494LeuPro: 2.494 ± 1.051
4.489LeuGln: 4.489 ± 0.597
2.993LeuArg: 2.993 ± 0.758
8.978LeuSer: 8.978 ± 1.835
2.494LeuThr: 2.494 ± 1.638
6.983LeuVal: 6.983 ± 0.879
0.998LeuTrp: 0.998 ± 0.614
1.995LeuTyr: 1.995 ± 0.695
0.0LeuXaa: 0.0 ± 0.0
Met
0.998MetAla: 0.998 ± 0.75
1.496MetCys: 1.496 ± 0.787
1.496MetAsp: 1.496 ± 1.216
0.998MetGlu: 0.998 ± 0.614
0.499MetPhe: 0.499 ± 0.405
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.499MetMet: 0.499 ± 0.451
0.499MetAsn: 0.499 ± 0.405
0.0MetPro: 0.0 ± 0.0
1.496MetGln: 1.496 ± 0.539
3.491MetArg: 3.491 ± 1.188
0.499MetSer: 0.499 ± 0.541
1.995MetThr: 1.995 ± 1.149
0.499MetVal: 0.499 ± 0.451
0.499MetTrp: 0.499 ± 0.451
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.995AsnAla: 1.995 ± 0.789
0.499AsnCys: 0.499 ± 0.656
0.998AsnAsp: 0.998 ± 0.497
1.995AsnGlu: 1.995 ± 1.131
0.998AsnPhe: 0.998 ± 0.811
1.496AsnGly: 1.496 ± 0.565
0.499AsnHis: 0.499 ± 0.541
0.998AsnIle: 0.998 ± 0.75
1.995AsnLys: 1.995 ± 1.211
2.993AsnLeu: 2.993 ± 0.812
0.499AsnMet: 0.499 ± 0.405
2.494AsnAsn: 2.494 ± 1.533
3.99AsnPro: 3.99 ± 1.199
1.496AsnGln: 1.496 ± 0.787
2.993AsnArg: 2.993 ± 1.09
2.993AsnSer: 2.993 ± 0.668
2.494AsnThr: 2.494 ± 0.778
2.494AsnVal: 2.494 ± 1.271
0.499AsnTrp: 0.499 ± 0.405
1.995AsnTyr: 1.995 ± 1.149
0.0AsnXaa: 0.0 ± 0.0
Pro
5.486ProAla: 5.486 ± 1.391
1.995ProCys: 1.995 ± 1.487
3.491ProAsp: 3.491 ± 1.263
4.489ProGlu: 4.489 ± 1.783
0.998ProPhe: 0.998 ± 0.727
5.985ProGly: 5.985 ± 1.49
2.993ProHis: 2.993 ± 1.989
0.499ProIle: 0.499 ± 0.405
4.988ProLys: 4.988 ± 2.125
7.481ProLeu: 7.481 ± 2.334
0.499ProMet: 0.499 ± 0.405
1.995ProAsn: 1.995 ± 0.831
13.965ProPro: 13.965 ± 9.576
3.491ProGln: 3.491 ± 2.52
5.486ProArg: 5.486 ± 1.426
7.481ProSer: 7.481 ± 1.421
7.98ProThr: 7.98 ± 2.038
2.494ProVal: 2.494 ± 0.941
0.499ProTrp: 0.499 ± 0.451
3.99ProTyr: 3.99 ± 1.689
0.0ProXaa: 0.0 ± 0.0
Gln
1.995GlnAla: 1.995 ± 1.131
1.496GlnCys: 1.496 ± 1.067
1.496GlnAsp: 1.496 ± 1.216
0.499GlnGlu: 0.499 ± 0.451
1.995GlnPhe: 1.995 ± 0.626
2.993GlnGly: 2.993 ± 1.106
0.998GlnHis: 0.998 ± 0.485
1.995GlnIle: 1.995 ± 0.863
0.998GlnLys: 0.998 ± 0.596
3.491GlnLeu: 3.491 ± 0.775
2.494GlnMet: 2.494 ± 1.016
1.995GlnAsn: 1.995 ± 0.831
5.486GlnPro: 5.486 ± 2.729
0.998GlnGln: 0.998 ± 0.485
3.491GlnArg: 3.491 ± 1.27
1.496GlnSer: 1.496 ± 0.386
0.998GlnThr: 0.998 ± 0.75
1.995GlnVal: 1.995 ± 0.775
0.0GlnTrp: 0.0 ± 0.0
0.998GlnTyr: 0.998 ± 0.811
0.0GlnXaa: 0.0 ± 0.0
Arg
5.985ArgAla: 5.985 ± 1.44
1.995ArgCys: 1.995 ± 1.397
1.995ArgAsp: 1.995 ± 0.961
4.489ArgGlu: 4.489 ± 2.288
2.494ArgPhe: 2.494 ± 0.743
10.973ArgGly: 10.973 ± 4.427
1.496ArgHis: 1.496 ± 0.864
1.496ArgIle: 1.496 ± 0.932
1.995ArgLys: 1.995 ± 0.653
5.486ArgLeu: 5.486 ± 0.932
2.494ArgMet: 2.494 ± 1.156
1.496ArgAsn: 1.496 ± 1.012
7.481ArgPro: 7.481 ± 1.503
1.496ArgGln: 1.496 ± 0.73
7.481ArgArg: 7.481 ± 1.848
3.491ArgSer: 3.491 ± 1.409
1.995ArgThr: 1.995 ± 0.913
4.988ArgVal: 4.988 ± 2.172
0.499ArgTrp: 0.499 ± 0.656
2.494ArgTyr: 2.494 ± 1.045
0.0ArgXaa: 0.0 ± 0.0
Ser
5.985SerAla: 5.985 ± 1.284
1.496SerCys: 1.496 ± 0.858
4.988SerAsp: 4.988 ± 1.214
2.993SerGlu: 2.993 ± 1.156
0.499SerPhe: 0.499 ± 0.433
5.985SerGly: 5.985 ± 2.06
1.995SerHis: 1.995 ± 0.633
3.99SerIle: 3.99 ± 1.992
0.998SerLys: 0.998 ± 0.497
8.978SerLeu: 8.978 ± 1.816
0.0SerMet: 0.0 ± 0.0
1.496SerAsn: 1.496 ± 0.787
5.985SerPro: 5.985 ± 2.086
3.491SerGln: 3.491 ± 0.815
3.491SerArg: 3.491 ± 1.914
12.469SerSer: 12.469 ± 3.896
11.471SerThr: 11.471 ± 4.11
3.99SerVal: 3.99 ± 2.297
1.496SerTrp: 1.496 ± 0.932
0.499SerTyr: 0.499 ± 0.451
0.0SerXaa: 0.0 ± 0.0
Thr
3.491ThrAla: 3.491 ± 1.476
1.496ThrCys: 1.496 ± 0.755
2.993ThrAsp: 2.993 ± 1.223
4.489ThrGlu: 4.489 ± 0.717
1.496ThrPhe: 1.496 ± 0.766
5.486ThrGly: 5.486 ± 0.969
1.496ThrHis: 1.496 ± 1.071
3.99ThrIle: 3.99 ± 1.885
0.499ThrLys: 0.499 ± 0.433
5.985ThrLeu: 5.985 ± 1.405
1.995ThrMet: 1.995 ± 0.315
3.99ThrAsn: 3.99 ± 1.709
7.98ThrPro: 7.98 ± 1.35
1.995ThrGln: 1.995 ± 1.32
1.496ThrArg: 1.496 ± 0.386
5.486ThrSer: 5.486 ± 1.839
6.484ThrThr: 6.484 ± 1.713
5.985ThrVal: 5.985 ± 1.982
0.998ThrTrp: 0.998 ± 0.902
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.494ValAla: 2.494 ± 1.307
1.995ValCys: 1.995 ± 1.417
4.489ValAsp: 4.489 ± 1.329
4.489ValGlu: 4.489 ± 2.429
1.995ValPhe: 1.995 ± 1.192
3.99ValGly: 3.99 ± 1.42
0.499ValHis: 0.499 ± 0.451
6.983ValIle: 6.983 ± 0.647
2.494ValLys: 2.494 ± 0.982
5.985ValLeu: 5.985 ± 2.437
0.0ValMet: 0.0 ± 0.0
0.998ValAsn: 0.998 ± 0.865
6.484ValPro: 6.484 ± 1.001
1.995ValGln: 1.995 ± 0.653
4.988ValArg: 4.988 ± 0.653
3.99ValSer: 3.99 ± 1.219
5.486ValThr: 5.486 ± 1.693
4.988ValVal: 4.988 ± 1.909
0.998ValTrp: 0.998 ± 0.75
1.995ValTyr: 1.995 ± 1.131
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.998TrpAsp: 0.998 ± 0.596
0.998TrpGlu: 0.998 ± 0.902
0.0TrpPhe: 0.0 ± 0.0
0.998TrpGly: 0.998 ± 0.902
0.0TrpHis: 0.0 ± 0.0
0.998TrpIle: 0.998 ± 0.497
0.998TrpLys: 0.998 ± 0.497
0.0TrpLeu: 0.0 ± 0.0
0.499TrpMet: 0.499 ± 0.405
1.496TrpAsn: 1.496 ± 0.864
0.998TrpPro: 0.998 ± 0.497
0.0TrpGln: 0.0 ± 0.0
1.496TrpArg: 1.496 ± 1.271
0.998TrpSer: 0.998 ± 0.614
1.496TrpThr: 1.496 ± 0.858
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.499TyrAla: 0.499 ± 0.656
1.496TyrCys: 1.496 ± 1.012
0.998TyrAsp: 0.998 ± 0.471
2.993TyrGlu: 2.993 ± 1.09
0.998TyrPhe: 0.998 ± 0.471
1.496TyrGly: 1.496 ± 0.787
0.499TyrHis: 0.499 ± 0.405
0.998TyrIle: 0.998 ± 0.497
0.998TyrLys: 0.998 ± 0.485
1.496TyrLeu: 1.496 ± 0.766
0.0TyrMet: 0.0 ± 0.0
1.995TyrAsn: 1.995 ± 0.93
0.499TyrPro: 0.499 ± 0.451
2.494TyrGln: 2.494 ± 0.982
1.995TyrArg: 1.995 ± 0.633
0.998TyrSer: 0.998 ± 0.811
1.995TyrThr: 1.995 ± 1.329
1.496TyrVal: 1.496 ± 0.766
0.998TyrTrp: 0.998 ± 0.497
1.995TyrTyr: 1.995 ± 1.277
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2006 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski