Amino acid dipepetide frequency for Lolium latent virus (isolate Lolium/USA/US1/-) (LoLV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.918AlaAla: 7.918 ± 2.461
0.396AlaCys: 0.396 ± 0.207
3.167AlaAsp: 3.167 ± 1.055
6.334AlaGlu: 6.334 ± 2.859
3.167AlaPhe: 3.167 ± 0.914
5.146AlaGly: 5.146 ± 0.775
1.979AlaHis: 1.979 ± 0.613
4.751AlaIle: 4.751 ± 1.482
5.542AlaLys: 5.542 ± 1.546
5.938AlaLeu: 5.938 ± 1.864
2.375AlaMet: 2.375 ± 1.241
2.771AlaAsn: 2.771 ± 0.521
4.355AlaPro: 4.355 ± 1.212
4.355AlaGln: 4.355 ± 1.226
4.751AlaArg: 4.751 ± 1.211
8.709AlaSer: 8.709 ± 2.19
3.959AlaThr: 3.959 ± 1.368
6.73AlaVal: 6.73 ± 4.697
0.0AlaTrp: 0.0 ± 0.0
3.959AlaTyr: 3.959 ± 0.961
0.0AlaXaa: 0.0 ± 0.0
Cys
0.396CysAla: 0.396 ± 0.877
1.188CysCys: 1.188 ± 1.133
0.0CysAsp: 0.0 ± 0.0
1.584CysGlu: 1.584 ± 1.059
0.792CysPhe: 0.792 ± 0.414
0.792CysGly: 0.792 ± 0.414
0.396CysHis: 0.396 ± 1.14
0.396CysIle: 0.396 ± 0.877
0.792CysLys: 0.792 ± 1.104
1.584CysLeu: 1.584 ± 1.762
0.792CysMet: 0.792 ± 0.414
0.0CysAsn: 0.0 ± 0.0
0.792CysPro: 0.792 ± 0.592
1.584CysGln: 1.584 ± 0.531
1.584CysArg: 1.584 ± 1.741
1.979CysSer: 1.979 ± 1.095
0.792CysThr: 0.792 ± 1.104
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.188CysTyr: 1.188 ± 0.942
0.0CysXaa: 0.0 ± 0.0
Asp
4.751AspAla: 4.751 ± 1.337
0.396AspCys: 0.396 ± 0.207
3.167AspAsp: 3.167 ± 1.654
3.959AspGlu: 3.959 ± 1.464
2.375AspPhe: 2.375 ± 0.475
2.375AspGly: 2.375 ± 1.78
2.375AspHis: 2.375 ± 0.856
2.375AspIle: 2.375 ± 1.025
1.188AspLys: 1.188 ± 0.522
5.938AspLeu: 5.938 ± 1.985
1.584AspMet: 1.584 ± 0.827
1.979AspAsn: 1.979 ± 0.846
3.563AspPro: 3.563 ± 0.778
2.375AspGln: 2.375 ± 1.241
1.584AspArg: 1.584 ± 1.289
2.771AspSer: 2.771 ± 0.7
1.979AspThr: 1.979 ± 0.694
1.188AspVal: 1.188 ± 0.485
0.792AspTrp: 0.792 ± 0.414
1.584AspTyr: 1.584 ± 0.827
0.0AspXaa: 0.0 ± 0.0
Glu
6.73GluAla: 6.73 ± 1.417
0.396GluCys: 0.396 ± 0.207
2.771GluAsp: 2.771 ± 0.997
2.771GluGlu: 2.771 ± 1.448
1.188GluPhe: 1.188 ± 0.485
3.959GluGly: 3.959 ± 0.741
1.979GluHis: 1.979 ± 1.034
3.959GluIle: 3.959 ± 1.246
4.355GluLys: 4.355 ± 1.725
3.563GluLeu: 3.563 ± 0.726
0.792GluMet: 0.792 ± 0.414
2.771GluAsn: 2.771 ± 0.521
3.167GluPro: 3.167 ± 0.711
4.355GluGln: 4.355 ± 1.146
3.167GluArg: 3.167 ± 0.914
2.375GluSer: 2.375 ± 0.475
4.751GluThr: 4.751 ± 1.241
3.167GluVal: 3.167 ± 1.654
0.792GluTrp: 0.792 ± 0.592
3.563GluTyr: 3.563 ± 0.993
0.0GluXaa: 0.0 ± 0.0
Phe
2.375PheAla: 2.375 ± 1.78
1.188PheCys: 1.188 ± 1.039
4.355PheAsp: 4.355 ± 0.968
3.167PheGlu: 3.167 ± 1.082
0.792PhePhe: 0.792 ± 1.302
0.792PheGly: 0.792 ± 0.414
1.188PheHis: 1.188 ± 0.62
1.584PheIle: 1.584 ± 0.827
1.584PheLys: 1.584 ± 0.827
3.563PheLeu: 3.563 ± 1.292
1.584PheMet: 1.584 ± 0.827
2.771PheAsn: 2.771 ± 1.452
1.584PhePro: 1.584 ± 0.531
1.979PheGln: 1.979 ± 0.673
1.584PheArg: 1.584 ± 0.531
1.979PheSer: 1.979 ± 1.245
1.584PheThr: 1.584 ± 0.562
1.584PheVal: 1.584 ± 0.624
0.0PheTrp: 0.0 ± 0.0
1.584PheTyr: 1.584 ± 0.978
0.0PheXaa: 0.0 ± 0.0
Gly
4.355GlyAla: 4.355 ± 1.901
1.584GlyCys: 1.584 ± 1.551
2.375GlyAsp: 2.375 ± 0.767
2.375GlyGlu: 2.375 ± 1.045
3.167GlyPhe: 3.167 ± 1.19
2.771GlyGly: 2.771 ± 2.122
1.188GlyHis: 1.188 ± 0.62
3.959GlyIle: 3.959 ± 1.417
3.959GlyLys: 3.959 ± 0.88
5.542GlyLeu: 5.542 ± 1.098
0.792GlyMet: 0.792 ± 0.49
1.188GlyAsn: 1.188 ± 0.62
2.771GlyPro: 2.771 ± 0.968
1.979GlyGln: 1.979 ± 1.097
2.771GlyArg: 2.771 ± 0.906
3.167GlySer: 3.167 ± 0.806
2.771GlyThr: 2.771 ± 1.265
3.167GlyVal: 3.167 ± 3.639
0.0GlyTrp: 0.0 ± 0.0
1.584GlyTyr: 1.584 ± 0.562
0.0GlyXaa: 0.0 ± 0.0
His
3.167HisAla: 3.167 ± 1.654
0.792HisCys: 0.792 ± 0.49
0.396HisAsp: 0.396 ± 0.207
1.979HisGlu: 1.979 ± 1.097
1.979HisPhe: 1.979 ± 0.613
2.375HisGly: 2.375 ± 0.748
1.979HisHis: 1.979 ± 1.783
1.188HisIle: 1.188 ± 0.522
1.188HisLys: 1.188 ± 0.522
3.167HisLeu: 3.167 ± 1.264
0.792HisMet: 0.792 ± 0.39
1.584HisAsn: 1.584 ± 0.562
2.771HisPro: 2.771 ± 0.617
1.979HisGln: 1.979 ± 1.214
1.979HisArg: 1.979 ± 1.034
1.584HisSer: 1.584 ± 1.27
1.188HisThr: 1.188 ± 1.133
0.396HisVal: 0.396 ± 0.877
0.396HisTrp: 0.396 ± 0.207
1.979HisTyr: 1.979 ± 0.613
0.0HisXaa: 0.0 ± 0.0
Ile
4.751IleAla: 4.751 ± 2.418
0.0IleCys: 0.0 ± 0.0
2.375IleAsp: 2.375 ± 0.745
3.563IleGlu: 3.563 ± 1.128
2.771IlePhe: 2.771 ± 1.282
2.771IleGly: 2.771 ± 1.017
2.771IleHis: 2.771 ± 0.734
1.979IleIle: 1.979 ± 0.694
1.979IleLys: 1.979 ± 1.08
4.751IleLeu: 4.751 ± 2.504
1.188IleMet: 1.188 ± 0.62
1.584IleAsn: 1.584 ± 0.827
3.167IlePro: 3.167 ± 1.029
1.979IleGln: 1.979 ± 0.694
2.771IleArg: 2.771 ± 0.7
1.979IleSer: 1.979 ± 1.884
5.542IleThr: 5.542 ± 1.296
2.771IleVal: 2.771 ± 1.017
0.0IleTrp: 0.0 ± 0.0
1.979IleTyr: 1.979 ± 1.034
0.0IleXaa: 0.0 ± 0.0
Lys
5.146LysAla: 5.146 ± 0.73
0.0LysCys: 0.0 ± 0.0
2.771LysAsp: 2.771 ± 1.448
2.771LysGlu: 2.771 ± 1.029
1.584LysPhe: 1.584 ± 0.827
3.167LysGly: 3.167 ± 2.073
0.396LysHis: 0.396 ± 0.207
1.188LysIle: 1.188 ± 0.485
1.584LysLys: 1.584 ± 0.562
5.542LysLeu: 5.542 ± 1.373
1.584LysMet: 1.584 ± 0.827
2.375LysAsn: 2.375 ± 0.856
1.188LysPro: 1.188 ± 1.089
3.959LysGln: 3.959 ± 1.33
1.188LysArg: 1.188 ± 0.62
4.355LysSer: 4.355 ± 0.976
4.751LysThr: 4.751 ± 1.421
1.188LysVal: 1.188 ± 0.485
1.584LysTrp: 1.584 ± 0.827
1.188LysTyr: 1.188 ± 0.774
0.0LysXaa: 0.0 ± 0.0
Leu
5.938LeuAla: 5.938 ± 2.205
1.584LeuCys: 1.584 ± 1.748
3.167LeuAsp: 3.167 ± 1.082
4.751LeuGlu: 4.751 ± 2.01
2.771LeuPhe: 2.771 ± 1.017
4.355LeuGly: 4.355 ± 1.212
2.375LeuHis: 2.375 ± 0.91
5.542LeuIle: 5.542 ± 2.272
5.938LeuLys: 5.938 ± 1.622
6.73LeuLeu: 6.73 ± 1.625
0.396LeuMet: 0.396 ± 0.207
5.146LeuAsn: 5.146 ± 1.224
7.918LeuPro: 7.918 ± 3.071
4.355LeuGln: 4.355 ± 1.81
6.334LeuArg: 6.334 ± 3.243
5.146LeuSer: 5.146 ± 1.627
6.73LeuThr: 6.73 ± 1.817
2.771LeuVal: 2.771 ± 1.017
1.584LeuTrp: 1.584 ± 0.531
3.167LeuTyr: 3.167 ± 1.654
0.0LeuXaa: 0.0 ± 0.0
Met
2.375MetAla: 2.375 ± 1.576
0.0MetCys: 0.0 ± 0.0
0.792MetAsp: 0.792 ± 0.414
1.584MetGlu: 1.584 ± 0.531
0.792MetPhe: 0.792 ± 0.49
1.188MetGly: 1.188 ± 0.62
0.396MetHis: 0.396 ± 0.207
0.396MetIle: 0.396 ± 0.207
1.188MetLys: 1.188 ± 0.62
2.375MetLeu: 2.375 ± 1.241
0.396MetMet: 0.396 ± 0.207
0.396MetAsn: 0.396 ± 0.207
0.792MetPro: 0.792 ± 0.414
1.584MetGln: 1.584 ± 0.827
0.792MetArg: 0.792 ± 0.414
2.375MetSer: 2.375 ± 2.233
1.979MetThr: 1.979 ± 1.034
2.375MetVal: 2.375 ± 1.191
0.396MetTrp: 0.396 ± 0.207
0.792MetTyr: 0.792 ± 0.414
0.0MetXaa: 0.0 ± 0.0
Asn
2.375AsnAla: 2.375 ± 0.856
2.375AsnCys: 2.375 ± 0.745
1.188AsnAsp: 1.188 ± 0.62
2.375AsnGlu: 2.375 ± 1.548
1.584AsnPhe: 1.584 ± 0.827
1.584AsnGly: 1.584 ± 0.98
0.396AsnHis: 0.396 ± 0.207
2.375AsnIle: 2.375 ± 1.639
1.188AsnLys: 1.188 ± 0.62
3.959AsnLeu: 3.959 ± 1.507
1.979AsnMet: 1.979 ± 0.652
1.188AsnAsn: 1.188 ± 0.485
2.771AsnPro: 2.771 ± 1.017
0.792AsnGln: 0.792 ± 0.414
1.979AsnArg: 1.979 ± 1.034
3.563AsnSer: 3.563 ± 0.888
2.771AsnThr: 2.771 ± 0.899
3.167AsnVal: 3.167 ± 0.635
0.792AsnTrp: 0.792 ± 1.149
0.792AsnTyr: 0.792 ± 1.104
0.0AsnXaa: 0.0 ± 0.0
Pro
3.563ProAla: 3.563 ± 2.328
0.396ProCys: 0.396 ± 0.207
5.542ProAsp: 5.542 ± 1.798
2.771ProGlu: 2.771 ± 1.033
2.375ProPhe: 2.375 ± 1.78
1.979ProGly: 1.979 ± 0.846
3.167ProHis: 3.167 ± 3.565
3.563ProIle: 3.563 ± 1.128
3.563ProLys: 3.563 ± 1.454
4.355ProLeu: 4.355 ± 2.279
1.584ProMet: 1.584 ± 0.98
1.188ProAsn: 1.188 ± 1.062
4.751ProPro: 4.751 ± 2.532
1.188ProGln: 1.188 ± 1.062
4.751ProArg: 4.751 ± 1.112
6.73ProSer: 6.73 ± 1.417
7.126ProThr: 7.126 ± 1.917
4.751ProVal: 4.751 ± 2.01
1.979ProTrp: 1.979 ± 1.05
1.979ProTyr: 1.979 ± 0.613
0.0ProXaa: 0.0 ± 0.0
Gln
3.959GlnAla: 3.959 ± 0.88
0.792GlnCys: 0.792 ± 0.592
5.542GlnAsp: 5.542 ± 1.917
1.188GlnGlu: 1.188 ± 0.485
1.188GlnPhe: 1.188 ± 0.485
1.979GlnGly: 1.979 ± 0.694
1.188GlnHis: 1.188 ± 0.62
1.979GlnIle: 1.979 ± 0.613
2.375GlnLys: 2.375 ± 1.241
3.167GlnLeu: 3.167 ± 0.711
1.584GlnMet: 1.584 ± 1.059
1.188GlnAsn: 1.188 ± 0.62
5.542GlnPro: 5.542 ± 1.027
1.979GlnGln: 1.979 ± 1.074
1.979GlnArg: 1.979 ± 1.034
2.771GlnSer: 2.771 ± 1.066
4.355GlnThr: 4.355 ± 0.95
2.375GlnVal: 2.375 ± 0.616
1.188GlnTrp: 1.188 ± 0.522
2.375GlnTyr: 2.375 ± 1.113
0.0GlnXaa: 0.0 ± 0.0
Arg
5.542ArgAla: 5.542 ± 1.812
1.979ArgCys: 1.979 ± 2.211
1.979ArgAsp: 1.979 ± 0.846
2.375ArgGlu: 2.375 ± 1.576
1.188ArgPhe: 1.188 ± 1.133
1.584ArgGly: 1.584 ± 1.408
2.375ArgHis: 2.375 ± 1.169
3.167ArgIle: 3.167 ± 0.806
1.979ArgLys: 1.979 ± 0.694
3.959ArgLeu: 3.959 ± 0.856
1.584ArgMet: 1.584 ± 0.827
3.167ArgAsn: 3.167 ± 1.654
4.355ArgPro: 4.355 ± 1.106
4.355ArgGln: 4.355 ± 0.928
3.959ArgArg: 3.959 ± 1.692
3.167ArgSer: 3.167 ± 2.366
3.959ArgThr: 3.959 ± 1.821
4.355ArgVal: 4.355 ± 1.031
0.396ArgTrp: 0.396 ± 0.207
2.375ArgTyr: 2.375 ± 0.767
0.0ArgXaa: 0.0 ± 0.0
Ser
4.751SerAla: 4.751 ± 1.646
0.792SerCys: 0.792 ± 0.592
2.375SerAsp: 2.375 ± 0.475
5.938SerGlu: 5.938 ± 0.823
1.979SerPhe: 1.979 ± 1.095
2.375SerGly: 2.375 ± 1.045
1.979SerHis: 1.979 ± 0.514
3.959SerIle: 3.959 ± 1.323
3.563SerLys: 3.563 ± 1.454
7.522SerLeu: 7.522 ± 2.56
1.188SerMet: 1.188 ± 0.999
1.979SerAsn: 1.979 ± 1.096
5.542SerPro: 5.542 ± 0.885
2.771SerGln: 2.771 ± 0.521
5.542SerArg: 5.542 ± 1.633
5.146SerSer: 5.146 ± 5.08
4.355SerThr: 4.355 ± 0.976
2.375SerVal: 2.375 ± 0.856
0.792SerTrp: 0.792 ± 0.414
2.771SerTyr: 2.771 ± 1.209
0.0SerXaa: 0.0 ± 0.0
Thr
6.334ThrAla: 6.334 ± 2.237
0.396ThrCys: 0.396 ± 0.207
4.355ThrAsp: 4.355 ± 4.035
3.563ThrGlu: 3.563 ± 1.246
3.959ThrPhe: 3.959 ± 1.388
4.355ThrGly: 4.355 ± 1.031
3.959ThrHis: 3.959 ± 1.611
2.771ThrIle: 2.771 ± 0.521
2.375ThrLys: 2.375 ± 0.616
6.334ThrLeu: 6.334 ± 1.712
0.396ThrMet: 0.396 ± 1.181
3.563ThrAsn: 3.563 ± 0.888
6.334ThrPro: 6.334 ± 1.967
2.375ThrGln: 2.375 ± 1.025
3.959ThrArg: 3.959 ± 1.196
5.542ThrSer: 5.542 ± 1.916
3.959ThrThr: 3.959 ± 1.327
4.751ThrVal: 4.751 ± 1.562
0.792ThrTrp: 0.792 ± 0.49
2.771ThrTyr: 2.771 ± 0.7
0.0ThrXaa: 0.0 ± 0.0
Val
5.542ValAla: 5.542 ± 2.934
0.396ValCys: 0.396 ± 0.207
1.584ValAsp: 1.584 ± 0.992
3.959ValGlu: 3.959 ± 1.224
2.375ValPhe: 2.375 ± 1.025
4.355ValGly: 4.355 ± 2.586
0.792ValHis: 0.792 ± 0.592
2.771ValIle: 2.771 ± 1.035
1.188ValLys: 1.188 ± 0.485
3.167ValLeu: 3.167 ± 1.453
1.188ValMet: 1.188 ± 1.102
1.584ValAsn: 1.584 ± 0.98
4.751ValPro: 4.751 ± 0.775
2.375ValGln: 2.375 ± 1.241
4.355ValArg: 4.355 ± 1.031
2.771ValSer: 2.771 ± 1.017
4.751ValThr: 4.751 ± 1.337
3.167ValVal: 3.167 ± 1.305
0.396ValTrp: 0.396 ± 0.575
1.979ValTyr: 1.979 ± 0.673
0.0ValXaa: 0.0 ± 0.0
Trp
1.584TrpAla: 1.584 ± 0.562
0.792TrpCys: 0.792 ± 1.635
0.0TrpAsp: 0.0 ± 0.0
1.188TrpGlu: 1.188 ± 0.62
0.396TrpPhe: 0.396 ± 0.207
0.792TrpGly: 0.792 ± 0.49
0.0TrpHis: 0.0 ± 0.0
0.792TrpIle: 0.792 ± 0.414
0.396TrpLys: 0.396 ± 0.207
0.792TrpLeu: 0.792 ± 0.414
0.396TrpMet: 0.396 ± 0.207
0.792TrpAsn: 0.792 ± 0.49
0.396TrpPro: 0.396 ± 0.716
1.188TrpGln: 1.188 ± 0.62
0.792TrpArg: 0.792 ± 0.414
0.0TrpSer: 0.0 ± 0.0
0.792TrpThr: 0.792 ± 1.432
1.584TrpVal: 1.584 ± 0.624
0.396TrpTrp: 0.396 ± 0.207
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.751TyrAla: 4.751 ± 1.713
1.188TyrCys: 1.188 ± 1.039
0.396TyrAsp: 0.396 ± 0.207
2.375TyrGlu: 2.375 ± 0.856
0.396TyrPhe: 0.396 ± 0.207
2.771TyrGly: 2.771 ± 0.906
1.979TyrHis: 1.979 ± 1.214
1.979TyrIle: 1.979 ± 0.613
1.584TyrLys: 1.584 ± 0.531
4.751TyrLeu: 4.751 ± 1.293
0.396TyrMet: 0.396 ± 0.575
1.979TyrAsn: 1.979 ± 0.673
0.792TyrPro: 0.792 ± 0.414
1.188TyrGln: 1.188 ± 1.91
1.979TyrArg: 1.979 ± 1.584
1.584TyrSer: 1.584 ± 0.827
4.751TyrThr: 4.751 ± 1.358
1.979TyrVal: 1.979 ± 0.514
0.792TyrTrp: 0.792 ± 0.749
1.584TyrTyr: 1.584 ± 0.562
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2527 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski