Amino acid dipepetide frequency for Pseudomassariella vexata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.128AlaAla: 9.128 ± 0.063	1.142AlaCys: 1.142 ± 0.016	4.297AlaAsp: 4.297 ± 0.03	5.087AlaGlu: 5.087 ± 0.048	3.151AlaPhe: 3.151 ± 0.029	5.964AlaGly: 5.964 ± 0.039	1.746AlaHis: 1.746 ± 0.017	4.301AlaIle: 4.301 ± 0.028	4.181AlaLys: 4.181 ± 0.038	7.675AlaLeu: 7.675 ± 0.044	2.074AlaMet: 2.074 ± 0.02	3.094AlaAsn: 3.094 ± 0.024	4.645AlaPro: 4.645 ± 0.039	3.385AlaGln: 3.385 ± 0.028	4.703AlaArg: 4.703 ± 0.033	7.161AlaSer: 7.161 ± 0.044	5.46AlaThr: 5.46 ± 0.032	5.525AlaVal: 5.525 ± 0.031	1.195AlaTrp: 1.195 ± 0.017	2.206AlaTyr: 2.206 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	1.005CysAla: 1.005 ± 0.016	0.29CysCys: 0.29 ± 0.008	0.698CysAsp: 0.698 ± 0.012	0.624CysGlu: 0.624 ± 0.013	0.588CysPhe: 0.588 ± 0.009	1.005CysGly: 1.005 ± 0.018	0.367CysHis: 0.367 ± 0.009	0.755CysIle: 0.755 ± 0.011	0.544CysLys: 0.544 ± 0.011	1.316CysLeu: 1.316 ± 0.017	0.286CysMet: 0.286 ± 0.006	0.46CysAsn: 0.46 ± 0.009	0.69CysPro: 0.69 ± 0.014	0.487CysGln: 0.487 ± 0.009	0.809CysArg: 0.809 ± 0.013	0.996CysSer: 0.996 ± 0.014	0.765CysThr: 0.765 ± 0.012	0.831CysVal: 0.831 ± 0.013	0.232CysTrp: 0.232 ± 0.007	0.373CysTyr: 0.373 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.733AspAla: 4.733 ± 0.03	0.65AspCys: 0.65 ± 0.012	4.23AspAsp: 4.23 ± 0.046	4.476AspGlu: 4.476 ± 0.039	2.223AspPhe: 2.223 ± 0.02	4.239AspGly: 4.239 ± 0.03	1.233AspHis: 1.233 ± 0.017	2.987AspIle: 2.987 ± 0.024	2.439AspLys: 2.439 ± 0.021	4.901AspLeu: 4.901 ± 0.03	1.368AspMet: 1.368 ± 0.015	1.957AspAsn: 1.957 ± 0.02	3.165AspPro: 3.165 ± 0.023	1.84AspGln: 1.84 ± 0.02	2.933AspArg: 2.933 ± 0.031	3.996AspSer: 3.996 ± 0.035	2.926AspThr: 2.926 ± 0.025	3.768AspVal: 3.768 ± 0.031	0.924AspTrp: 0.924 ± 0.013	1.614AspTyr: 1.614 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.285GluAla: 5.285 ± 0.041	0.649GluCys: 0.649 ± 0.013	4.087GluAsp: 4.087 ± 0.038	4.958GluGlu: 4.958 ± 0.054	1.954GluPhe: 1.954 ± 0.02	3.744GluGly: 3.744 ± 0.026	1.363GluHis: 1.363 ± 0.015	2.896GluIle: 2.896 ± 0.028	3.613GluLys: 3.613 ± 0.036	5.031GluLeu: 5.031 ± 0.035	1.507GluMet: 1.507 ± 0.017	2.239GluAsn: 2.239 ± 0.022	2.718GluPro: 2.718 ± 0.035	2.311GluGln: 2.311 ± 0.022	3.705GluArg: 3.705 ± 0.029	4.035GluSer: 4.035 ± 0.036	3.477GluThr: 3.477 ± 0.028	3.578GluVal: 3.578 ± 0.028	0.884GluTrp: 0.884 ± 0.013	1.649GluTyr: 1.649 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.123PheAla: 3.123 ± 0.027	0.584PheCys: 0.584 ± 0.01	2.294PheAsp: 2.294 ± 0.024	2.131PheGlu: 2.131 ± 0.024	1.67PhePhe: 1.67 ± 0.022	2.977PheGly: 2.977 ± 0.033	0.915PheHis: 0.915 ± 0.013	1.859PheIle: 1.859 ± 0.02	1.538PheLys: 1.538 ± 0.02	3.425PheLeu: 3.425 ± 0.034	0.846PheMet: 0.846 ± 0.013	1.499PheAsn: 1.499 ± 0.019	1.946PhePro: 1.946 ± 0.022	1.372PheGln: 1.372 ± 0.016	1.944PheArg: 1.944 ± 0.019	3.002PheSer: 3.002 ± 0.023	2.209PheThr: 2.209 ± 0.02	2.499PheVal: 2.499 ± 0.025	0.695PheTrp: 0.695 ± 0.012	1.116PheTyr: 1.116 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.478GlyAla: 5.478 ± 0.04	0.954GlyCys: 0.954 ± 0.014	3.738GlyAsp: 3.738 ± 0.029	3.622GlyGlu: 3.622 ± 0.026	2.97GlyPhe: 2.97 ± 0.027	6.053GlyGly: 6.053 ± 0.055	1.77GlyHis: 1.77 ± 0.021	3.704GlyIle: 3.704 ± 0.028	3.58GlyLys: 3.58 ± 0.032	6.231GlyLeu: 6.231 ± 0.04	1.735GlyMet: 1.735 ± 0.019	2.768GlyAsn: 2.768 ± 0.025	3.413GlyPro: 3.413 ± 0.031	2.589GlyGln: 2.589 ± 0.027	4.142GlyArg: 4.142 ± 0.03	5.819GlySer: 5.819 ± 0.04	4.256GlyThr: 4.256 ± 0.031	4.528GlyVal: 4.528 ± 0.034	1.229GlyTrp: 1.229 ± 0.017	2.17GlyTyr: 2.17 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.81HisAla: 1.81 ± 0.021	0.369HisCys: 0.369 ± 0.008	1.339HisAsp: 1.339 ± 0.017	1.313HisGlu: 1.313 ± 0.017	0.931HisPhe: 0.931 ± 0.013	1.777HisGly: 1.777 ± 0.019	0.869HisHis: 0.869 ± 0.018	1.213HisIle: 1.213 ± 0.017	0.957HisLys: 0.957 ± 0.014	2.192HisLeu: 2.192 ± 0.02	0.542HisMet: 0.542 ± 0.01	0.885HisAsn: 0.885 ± 0.013	1.599HisPro: 1.599 ± 0.018	0.993HisGln: 0.993 ± 0.013	1.502HisArg: 1.502 ± 0.018	1.798HisSer: 1.798 ± 0.021	1.257HisThr: 1.257 ± 0.015	1.435HisVal: 1.435 ± 0.014	0.348HisTrp: 0.348 ± 0.007	0.701HisTyr: 0.701 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.182IleAla: 4.182 ± 0.031	0.794IleCys: 0.794 ± 0.013	2.818IleAsp: 2.818 ± 0.025	2.788IleGlu: 2.788 ± 0.021	2.034IlePhe: 2.034 ± 0.023	3.279IleGly: 3.279 ± 0.029	1.169IleHis: 1.169 ± 0.015	2.566IleIle: 2.566 ± 0.023	2.26IleLys: 2.26 ± 0.023	4.493IleLeu: 4.493 ± 0.035	1.152IleMet: 1.152 ± 0.015	1.861IleAsn: 1.861 ± 0.02	3.019IlePro: 3.019 ± 0.026	1.866IleGln: 1.866 ± 0.022	2.762IleArg: 2.762 ± 0.024	3.883IleSer: 3.883 ± 0.026	2.926IleThr: 2.926 ± 0.023	3.263IleVal: 3.263 ± 0.023	0.778IleTrp: 0.778 ± 0.012	1.406IleTyr: 1.406 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.34LysAla: 4.34 ± 0.035	0.53LysCys: 0.53 ± 0.011	2.742LysAsp: 2.742 ± 0.026	3.225LysGlu: 3.225 ± 0.029	1.531LysPhe: 1.531 ± 0.021	3.057LysGly: 3.057 ± 0.029	1.144LysHis: 1.144 ± 0.016	2.265LysIle: 2.265 ± 0.024	3.322LysLys: 3.322 ± 0.044	4.142LysLeu: 4.142 ± 0.029	1.121LysMet: 1.121 ± 0.013	1.739LysAsn: 1.739 ± 0.02	2.796LysPro: 2.796 ± 0.025	1.873LysGln: 1.873 ± 0.018	3.334LysArg: 3.334 ± 0.027	3.514LysSer: 3.514 ± 0.026	2.965LysThr: 2.965 ± 0.025	2.93LysVal: 2.93 ± 0.025	0.728LysTrp: 0.728 ± 0.011	1.416LysTyr: 1.416 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.798LeuAla: 7.798 ± 0.043	1.235LeuCys: 1.235 ± 0.015	5.062LeuAsp: 5.062 ± 0.033	5.305LeuGlu: 5.305 ± 0.043	3.323LeuPhe: 3.323 ± 0.032	6.139LeuGly: 6.139 ± 0.034	2.13LeuHis: 2.13 ± 0.021	3.952LeuIle: 3.952 ± 0.03	4.208LeuLys: 4.208 ± 0.032	8.185LeuLeu: 8.185 ± 0.06	1.882LeuMet: 1.882 ± 0.021	3.175LeuAsn: 3.175 ± 0.028	5.357LeuPro: 5.357 ± 0.034	3.665LeuGln: 3.665 ± 0.029	5.498LeuArg: 5.498 ± 0.035	7.077LeuSer: 7.077 ± 0.039	4.817LeuThr: 4.817 ± 0.033	5.601LeuVal: 5.601 ± 0.039	1.265LeuTrp: 1.265 ± 0.017	2.364LeuTyr: 2.364 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.398MetAla: 2.398 ± 0.019	0.276MetCys: 0.276 ± 0.007	1.329MetAsp: 1.329 ± 0.017	1.292MetGlu: 1.292 ± 0.018	0.791MetPhe: 0.791 ± 0.012	1.597MetGly: 1.597 ± 0.019	0.529MetHis: 0.529 ± 0.011	1.047MetIle: 1.047 ± 0.016	1.106MetLys: 1.106 ± 0.015	1.962MetLeu: 1.962 ± 0.021	0.664MetMet: 0.664 ± 0.011	0.869MetAsn: 0.869 ± 0.012	1.385MetPro: 1.385 ± 0.019	0.909MetGln: 0.909 ± 0.015	1.347MetArg: 1.347 ± 0.015	1.935MetSer: 1.935 ± 0.022	1.427MetThr: 1.427 ± 0.016	1.464MetVal: 1.464 ± 0.016	0.3MetTrp: 0.3 ± 0.008	0.575MetTyr: 0.575 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.211AsnAla: 3.211 ± 0.027	0.489AsnCys: 0.489 ± 0.011	2.015AsnAsp: 2.015 ± 0.019	2.056AsnGlu: 2.056 ± 0.02	1.432AsnPhe: 1.432 ± 0.018	3.146AsnGly: 3.146 ± 0.03	0.888AsnHis: 0.888 ± 0.012	2.039AsnIle: 2.039 ± 0.021	1.599AsnLys: 1.599 ± 0.019	3.316AsnLeu: 3.316 ± 0.029	0.944AsnMet: 0.944 ± 0.014	1.553AsnAsn: 1.553 ± 0.022	2.467AsnPro: 2.467 ± 0.023	1.365AsnGln: 1.365 ± 0.015	1.924AsnArg: 1.924 ± 0.019	2.885AsnSer: 2.885 ± 0.025	2.28AsnThr: 2.28 ± 0.023	2.4AsnVal: 2.4 ± 0.022	0.595AsnTrp: 0.595 ± 0.012	1.114AsnTyr: 1.114 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.074ProAla: 5.074 ± 0.047	0.569ProCys: 0.569 ± 0.012	3.162ProAsp: 3.162 ± 0.025	3.658ProGlu: 3.658 ± 0.031	1.998ProPhe: 1.998 ± 0.019	3.972ProGly: 3.972 ± 0.037	1.304ProHis: 1.304 ± 0.017	2.576ProIle: 2.576 ± 0.023	2.688ProLys: 2.688 ± 0.024	4.617ProLeu: 4.617 ± 0.031	1.168ProMet: 1.168 ± 0.015	2.316ProAsn: 2.316 ± 0.024	4.825ProPro: 4.825 ± 0.059	2.433ProGln: 2.433 ± 0.026	3.341ProArg: 3.341 ± 0.03	5.608ProSer: 5.608 ± 0.043	3.948ProThr: 3.948 ± 0.031	3.54ProVal: 3.54 ± 0.034	0.783ProTrp: 0.783 ± 0.012	1.526ProTyr: 1.526 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.355GlnAla: 3.355 ± 0.028	0.458GlnCys: 0.458 ± 0.009	2.048GlnAsp: 2.048 ± 0.017	2.192GlnGlu: 2.192 ± 0.022	1.297GlnPhe: 1.297 ± 0.015	2.493GlnGly: 2.493 ± 0.025	1.074GlnHis: 1.074 ± 0.016	1.891GlnIle: 1.891 ± 0.019	1.956GlnLys: 1.956 ± 0.018	3.407GlnLeu: 3.407 ± 0.027	0.918GlnMet: 0.918 ± 0.014	1.553GlnAsn: 1.553 ± 0.022	2.466GlnPro: 2.466 ± 0.028	2.234GlnGln: 2.234 ± 0.042	2.536GlnArg: 2.536 ± 0.021	3.011GlnSer: 3.011 ± 0.028	2.291GlnThr: 2.291 ± 0.022	2.301GlnVal: 2.301 ± 0.021	0.593GlnTrp: 0.593 ± 0.011	1.196GlnTyr: 1.196 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.476ArgAla: 4.476 ± 0.032	0.764ArgCys: 0.764 ± 0.013	3.338ArgAsp: 3.338 ± 0.031	3.595ArgGlu: 3.595 ± 0.033	2.092ArgPhe: 2.092 ± 0.022	3.808ArgGly: 3.808 ± 0.029	1.604ArgHis: 1.604 ± 0.018	2.877ArgIle: 2.877 ± 0.026	3.4ArgLys: 3.4 ± 0.03	5.282ArgLeu: 5.282 ± 0.035	1.367ArgMet: 1.367 ± 0.017	2.278ArgAsn: 2.278 ± 0.023	3.431ArgPro: 3.431 ± 0.03	2.558ArgGln: 2.558 ± 0.026	4.871ArgArg: 4.871 ± 0.044	4.564ArgSer: 4.564 ± 0.045	3.232ArgThr: 3.232 ± 0.023	3.303ArgVal: 3.303 ± 0.025	0.959ArgTrp: 0.959 ± 0.014	1.616ArgTyr: 1.616 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.498SerAla: 6.498 ± 0.034	0.974SerCys: 0.974 ± 0.015	4.065SerAsp: 4.065 ± 0.035	3.909SerGlu: 3.909 ± 0.032	3.069SerPhe: 3.069 ± 0.026	5.66SerGly: 5.66 ± 0.036	1.933SerHis: 1.933 ± 0.02	4.014SerIle: 4.014 ± 0.03	3.695SerLys: 3.695 ± 0.026	6.945SerLeu: 6.945 ± 0.037	1.841SerMet: 1.841 ± 0.022	3.07SerAsn: 3.07 ± 0.025	5.213SerPro: 5.213 ± 0.049	3.227SerGln: 3.227 ± 0.023	4.964SerArg: 4.964 ± 0.038	8.46SerSer: 8.46 ± 0.065	5.553SerThr: 5.553 ± 0.04	4.584SerVal: 4.584 ± 0.032	1.173SerTrp: 1.173 ± 0.016	2.14SerTyr: 2.14 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.38ThrAla: 5.38 ± 0.039	0.849ThrCys: 0.849 ± 0.014	2.888ThrAsp: 2.888 ± 0.026	3.133ThrGlu: 3.133 ± 0.027	2.262ThrPhe: 2.262 ± 0.023	4.347ThrGly: 4.347 ± 0.038	1.287ThrHis: 1.287 ± 0.016	3.109ThrIle: 3.109 ± 0.03	2.716ThrLys: 2.716 ± 0.024	5.174ThrLeu: 5.174 ± 0.032	1.306ThrMet: 1.306 ± 0.015	2.276ThrAsn: 2.276 ± 0.023	4.221ThrPro: 4.221 ± 0.036	2.128ThrGln: 2.128 ± 0.021	3.167ThrArg: 3.167 ± 0.026	5.423ThrSer: 5.423 ± 0.04	4.47ThrThr: 4.47 ± 0.046	3.824ThrVal: 3.824 ± 0.029	0.9ThrTrp: 0.9 ± 0.015	1.681ThrTyr: 1.681 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.5ValAla: 5.5 ± 0.038	0.874ValCys: 0.874 ± 0.014	3.788ValAsp: 3.788 ± 0.028	3.89ValGlu: 3.89 ± 0.029	2.542ValPhe: 2.542 ± 0.024	4.274ValGly: 4.274 ± 0.033	1.394ValHis: 1.394 ± 0.015	3.027ValIle: 3.027 ± 0.025	2.954ValLys: 2.954 ± 0.026	5.709ValLeu: 5.709 ± 0.034	1.43ValMet: 1.43 ± 0.019	2.307ValAsn: 2.307 ± 0.021	3.597ValPro: 3.597 ± 0.028	2.356ValGln: 2.356 ± 0.02	3.384ValArg: 3.384 ± 0.025	4.656ValSer: 4.656 ± 0.028	3.647ValThr: 3.647 ± 0.027	4.602ValVal: 4.602 ± 0.037	0.925ValTrp: 0.925 ± 0.015	1.765ValTyr: 1.765 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.177TrpAla: 1.177 ± 0.017	0.218TrpCys: 0.218 ± 0.006	0.964TrpAsp: 0.964 ± 0.015	0.855TrpGlu: 0.855 ± 0.013	0.572TrpPhe: 0.572 ± 0.011	1.038TrpGly: 1.038 ± 0.015	0.376TrpHis: 0.376 ± 0.008	0.81TrpIle: 0.81 ± 0.012	0.827TrpLys: 0.827 ± 0.012	1.403TrpLeu: 1.403 ± 0.017	0.402TrpMet: 0.402 ± 0.008	0.665TrpAsn: 0.665 ± 0.012	0.652TrpPro: 0.652 ± 0.013	0.598TrpGln: 0.598 ± 0.009	0.995TrpArg: 0.995 ± 0.015	1.089TrpSer: 1.089 ± 0.017	0.968TrpThr: 0.968 ± 0.014	0.933TrpVal: 0.933 ± 0.014	0.294TrpTrp: 0.294 ± 0.008	0.453TrpTyr: 0.453 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.167TyrAla: 2.167 ± 0.02	0.453TyrCys: 0.453 ± 0.01	1.698TyrAsp: 1.698 ± 0.018	1.575TyrGlu: 1.575 ± 0.018	1.215TyrPhe: 1.215 ± 0.016	2.182TyrGly: 2.182 ± 0.023	0.734TyrHis: 0.734 ± 0.011	1.413TyrIle: 1.413 ± 0.017	1.133TyrLys: 1.133 ± 0.017	2.632TyrLeu: 2.632 ± 0.022	0.647TyrMet: 0.647 ± 0.01	1.156TyrAsn: 1.156 ± 0.015	1.503TyrPro: 1.503 ± 0.017	1.079TyrGln: 1.079 ± 0.016	1.555TyrArg: 1.555 ± 0.019	2.072TyrSer: 2.072 ± 0.023	1.667TyrThr: 1.667 ± 0.021	1.712TyrVal: 1.712 ± 0.017	0.488TyrTrp: 0.488 ± 0.01	0.965TyrTyr: 0.965 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12557 proteins (5490982 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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